LOCUS       DAVMAH010000001        63215 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVMAH010000001 DAVMAH010000000
VERSION     DAVMAH010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 63215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63215
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.001"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(113..2071)
                     /gene="ftsH"
                     /locus_tag="VYO94_000001"
     CDS             complement(113..2071)
                     /gene="ftsH"
                     /locus_tag="VYO94_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV1758718.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2087..2629)
                     /gene="hpt"
                     /locus_tag="VYO94_000002"
     CDS             complement(2087..2629)
                     /gene="hpt"
                     /locus_tag="VYO94_000002"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV1758719.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2633..3910)
                     /gene="tilS"
                     /locus_tag="VYO94_000003"
     CDS             complement(2633..3910)
                     /gene="tilS"
                     /locus_tag="VYO94_000003"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV1758720.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3907..5175)
                     /locus_tag="VYO94_000004"
     CDS             complement(3907..5175)
                     /locus_tag="VYO94_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV1758721.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVHTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5295..5663)
                     /locus_tag="VYO94_000005"
     CDS             complement(5295..5663)
                     /locus_tag="VYO94_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV1758722.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5656..5922)
                     /locus_tag="VYO94_000006"
     CDS             complement(5656..5922)
                     /locus_tag="VYO94_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV1758723.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5990..9499)
                     /gene="mfd"
                     /locus_tag="VYO94_000007"
     CDS             complement(5990..9499)
                     /gene="mfd"
                     /locus_tag="VYO94_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV1758724.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPIQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFSVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9500..10069)
                     /locus_tag="VYO94_000008"
     CDS             complement(9500..10069)
                     /locus_tag="VYO94_000008"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV1758725.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10140..11255)
                     /gene="ychF"
                     /locus_tag="VYO94_000009"
     CDS             complement(10140..11255)
                     /gene="ychF"
                     /locus_tag="VYO94_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV1758726.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11339..11533)
                     /locus_tag="VYO94_000010"
     CDS             complement(11339..11533)
                     /locus_tag="VYO94_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV1758727.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11598..12734)
                     /gene="dnaN"
                     /locus_tag="VYO94_000011"
     CDS             complement(11598..12734)
                     /gene="dnaN"
                     /locus_tag="VYO94_000011"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV1758728.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12893..14254)
                     /gene="dnaA"
                     /locus_tag="VYO94_000012"
     CDS             complement(12893..14254)
                     /gene="dnaA"
                     /locus_tag="VYO94_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV1758729.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14467..15225)
                     /locus_tag="VYO94_000013"
     CDS             complement(14467..15225)
                     /locus_tag="VYO94_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV1758730.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNDEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15283..16464)
                     /locus_tag="VYO94_000014"
     CDS             complement(15283..16464)
                     /locus_tag="VYO94_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV1758731.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16647..17126
                     /gene="rlmH"
                     /locus_tag="VYO94_000015"
     CDS             16647..17126
                     /gene="rlmH"
                     /locus_tag="VYO94_000015"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV1758732.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17170..17243
                     /locus_tag="VYO94_000016"
     tRNA            17170..17243
                     /locus_tag="VYO94_000016"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17204..17206,aa:Arg,seq:tct)
     gene            17408..17533
                     /gene="comC"
                     /locus_tag="VYO94_000017"
     CDS             17408..17533
                     /gene="comC"
                     /locus_tag="VYO94_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV1758733.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRISRIILDFLFLRKK"
     gene            17554..18879
                     /locus_tag="VYO94_000018"
     CDS             17554..18879
                     /locus_tag="VYO94_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1758734.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYVFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVMVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18876..19628
                     /locus_tag="VYO94_000019"
     CDS             18876..19628
                     /locus_tag="VYO94_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1758735.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19680..19751
                     /locus_tag="VYO94_000020"
     tRNA            19680..19751
                     /locus_tag="VYO94_000020"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19713..19715,aa:Glu,seq:ttc)
     gene            19757..19830
                     /locus_tag="VYO94_000021"
     tRNA            19757..19830
                     /locus_tag="VYO94_000021"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19791..19793,aa:Asn,seq:gtt)
     gene            complement(19871..20413)
                     /locus_tag="VYO94_000022"
     CDS             complement(19871..20413)
                     /locus_tag="VYO94_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV1758736.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSIDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20541..22152
                     /locus_tag="VYO94_000023"
                     /pseudo
     CDS             20541..22152
                     /locus_tag="VYO94_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
     gene            complement(22182..24734)
                     /locus_tag="VYO94_000024"
     CDS             complement(22182..24734)
                     /locus_tag="VYO94_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV1758737.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYIIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24796..26418)
                     /locus_tag="VYO94_000025"
     CDS             complement(24796..26418)
                     /locus_tag="VYO94_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1758738.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26624..27649
                     /gene="trpS"
                     /locus_tag="VYO94_000026"
     CDS             26624..27649
                     /gene="trpS"
                     /locus_tag="VYO94_000026"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV1758739.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27801..29279
                     /gene="guaB"
                     /locus_tag="VYO94_000027"
     CDS             27801..29279
                     /gene="guaB"
                     /locus_tag="VYO94_000027"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV1758740.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29330..30427)
                     /gene="recF"
                     /locus_tag="VYO94_000028"
     CDS             complement(29330..30427)
                     /gene="recF"
                     /locus_tag="VYO94_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV1758741.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGD"
     gene            complement(30430..30798)
                     /gene="yaaA"
                     /locus_tag="VYO94_000029"
     CDS             complement(30430..30798)
                     /gene="yaaA"
                     /locus_tag="VYO94_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV1758742.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30957..32207
                     /locus_tag="VYO94_000030"
     CDS             30957..32207
                     /locus_tag="VYO94_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1758743.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMCPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKGWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            32204..33487
                     /locus_tag="VYO94_000031"
     CDS             32204..33487
                     /locus_tag="VYO94_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1758744.1"
                     /translation="MTKVVFEKKYYPAVKEMIYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33529..34350
                     /locus_tag="VYO94_000032"
     CDS             33529..34350
                     /locus_tag="VYO94_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1758745.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34361..34906
                     /gene="pgsA"
                     /locus_tag="VYO94_000033"
     CDS             34361..34906
                     /gene="pgsA"
                     /locus_tag="VYO94_000033"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV1758746.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIILIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34903..35730
                     /locus_tag="VYO94_000034"
     CDS             34903..35730
                     /locus_tag="VYO94_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1758747.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35715..36554
                     /locus_tag="VYO94_000035"
     CDS             35715..36554
                     /locus_tag="VYO94_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1758748.1"
                     /translation="MGIALENVNFTYQEGTPLALAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36547..37341
                     /locus_tag="VYO94_000036"
     CDS             36547..37341
                     /locus_tag="VYO94_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1758749.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37400..38218
                     /gene="mreC"
                     /locus_tag="VYO94_000037"
     CDS             37400..38218
                     /gene="mreC"
                     /locus_tag="VYO94_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV1758750.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38218..38712
                     /gene="mreD"
                     /locus_tag="VYO94_000038"
     CDS             38218..38712
                     /gene="mreD"
                     /locus_tag="VYO94_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV1758751.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38806..39984
                     /locus_tag="VYO94_000039"
     CDS             38806..39984
                     /locus_tag="VYO94_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV1758752.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40208..40987
                     /gene="rpsB"
                     /locus_tag="VYO94_000040"
     CDS             40208..40987
                     /gene="rpsB"
                     /locus_tag="VYO94_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV1758753.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41066..42106
                     /locus_tag="VYO94_000041"
     CDS             41066..42106
                     /locus_tag="VYO94_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV1758754.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            complement(42227..43153)
                     /gene="cysK"
                     /locus_tag="VYO94_000042"
     CDS             complement(42227..43153)
                     /gene="cysK"
                     /locus_tag="VYO94_000042"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV1758755.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEFEV"
     gene            complement(43438..44073)
                     /locus_tag="VYO94_000043"
     CDS             complement(43438..44073)
                     /locus_tag="VYO94_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV1758756.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            44129..45427
                     /locus_tag="VYO94_000044"
     CDS             44129..45427
                     /locus_tag="VYO94_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1758757.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLLCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            45424..46086
                     /locus_tag="VYO94_000045"
     CDS             45424..46086
                     /locus_tag="VYO94_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV1758758.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFYIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            46166..46714
                     /gene="raiA"
                     /locus_tag="VYO94_000046"
     CDS             46166..46714
                     /gene="raiA"
                     /locus_tag="VYO94_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV1758759.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            46850..48823
                     /locus_tag="VYO94_000047"
     CDS             46850..48823
                     /locus_tag="VYO94_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV1758760.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            48820..49272
                     /gene="rplI"
                     /locus_tag="VYO94_000048"
     CDS             48820..49272
                     /gene="rplI"
                     /locus_tag="VYO94_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV1758761.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            49316..50668
                     /gene="dnaB"
                     /locus_tag="VYO94_000049"
     CDS             49316..50668
                     /gene="dnaB"
                     /locus_tag="VYO94_000049"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV1758762.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            50670..50936
                     /locus_tag="VYO94_000050"
     CDS             50670..50936
                     /locus_tag="VYO94_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758763.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            51025..52371
                     /gene="cbpD"
                     /locus_tag="VYO94_000051"
     CDS             51025..52371
                     /gene="cbpD"
                     /locus_tag="VYO94_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV1758764.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLNGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGHSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      52454..52556
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            52627..52917
                     /locus_tag="VYO94_000052"
     CDS             52627..52917
                     /locus_tag="VYO94_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV1758765.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            52880..53638
                     /locus_tag="VYO94_000053"
     CDS             52880..53638
                     /locus_tag="VYO94_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1758766.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            53677..54684
                     /locus_tag="VYO94_000054"
     CDS             53677..54684
                     /locus_tag="VYO94_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1758767.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            54684..55412
                     /locus_tag="VYO94_000055"
     CDS             54684..55412
                     /locus_tag="VYO94_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1758768.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            55531..55989
                     /locus_tag="VYO94_000056"
     CDS             55531..55989
                     /locus_tag="VYO94_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV1758769.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALERVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            55991..58423
                     /locus_tag="VYO94_000057"
     CDS             55991..58423
                     /locus_tag="VYO94_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1758770.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEAL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQVYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            58744..59397
                     /gene="rr06"
                     /locus_tag="VYO94_000058"
     CDS             58744..59397
                     /gene="rr06"
                     /locus_tag="VYO94_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV1758771.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            59394..60725
                     /gene="hk06"
                     /locus_tag="VYO94_000059"
     CDS             59394..60725
                     /gene="hk06"
                     /locus_tag="VYO94_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV1758772.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            60808..61335
                     /locus_tag="VYO94_000060"
     CDS             60808..61335
                     /locus_tag="VYO94_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV1758773.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDVMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            61414..>63215
                     /gene="pspC"
                     /locus_tag="VYO94_000061"
     CDS             61414..>63215
                     /gene="pspC"
                     /locus_tag="VYO94_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV1758774.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVAVASLFMGSVVHATENEGIA
                     QVVTSSNMANTEHRKAAKQVDEYIEKMIQLDRRKHTQNVGLFTKLGAIKTEYLRGLSV
                     SKEKSTAELPSEIKAKLTAAFEQFKKDTLPTEPGKKVAEAKKKVEEAEKKVAEAKKKA
                     KAQKEEDHRNYPTITYKTLDLEIAEFDVKVKEAELELVKKEADESRNEGTINQAKAKV
                     ESEKAEATRLKKIKTDREKAEEEAKRRADAKEQDESKRRKSRGKRGALGEQATPDKKE
                     NDAKSSDSSVGEETLPSPSLKPGKKVAEAEKKVEEADKKAKAQKEEDRRNYPTNTYKT
                     LELEIAESDVKVKEAELELVKEEAKESRNEEKIKQAKAKVESKKAEATRLEKIKTDRK
                     KAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAEEPENPVPAPKPENPAEQPKAE
                     KPADQQAEEDYARRSEEEYNRLTQQQPPKPEQPAPAPKIGWKQENGMWYFYNTDGSMA
                     TGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGD
                     MATGWLQYNGSWYYLNANGDMATGWFQYNGSWYYL"
BASE COUNT        19847 a        10755 c        12594 g        20019 t
ORIGIN      
        1 ctgaatatca aaaaagaaag gacaaaattt gtcctttctc gagcttagct gacttcaacc
       61 cactacagtt gacaaagagc caaaaaaaga gaggctccag cctctctcag ggttattttt
      121 cgtcattcat ttttgacttt acttcatcat aggatagtgc atgagattcc tcttctactg
      181 cttcaggcat ctttcctgtt tcgtaaagag ctttaatttg tgtactatcc aatgtttcgt
      241 atttcaataa tgcttctgca attaacttgt gagtttcacg atttgactga ataatttcag
      301 cagctttatt tcgtgcctca tttaataatg aacgaacctc ttcatcaatt tcataagctg
      361 tttgttctga aattgatttt tgaggactct gtgcaccaag catagcatgg tttccttcat
      421 attgtactgg gccaagtttt tcactcatac cgtactctgt aaccattgca cgtgccattt
      481 gtgtcgcttg ttcaaagtcg tttgaagctc ctgtagtttg gacattaaag ataatttctt
      541 cagctacacg tccacccatt aagccagcca attgctcttt catatcttct ttagatagaa
      601 gcatttgatc ctctttagga agtgcaatca tgtatccgcc tgcacggccg cgtggtacaa
      661 ttgtaacctt atggacaacg cgagcattcg acaagactag accaacaatg gtatgtcctg
      721 cctcatggta agcaaccaat tctcgttctt tttgtgaaac tgtcttatct ttcttagaag
      781 gtccagcaat aactctatct tctgcttcat caatatctga agcatcaatt atcgatttat
      841 tgcgacgagc agcaactaaa gctgcttcat tcaagacatt ctctaaatca gcaccaacaa
      901 agcctggagt ttgttgagcc actaatttca aatcaacatc ttctgctaaa ggcttgttct
      961 tagcgtgaac tttcaagatt gcttcacgac ctttaacatc aggacggcca accaatactt
     1021 ttctatcaaa acgtcctgga cgcaaaaggg caggatcaag tacatctgaa cggtttgtcg
     1081 cagcgatgac gataatccct tcatttccct caaaaccatc catctcaatc aaaagttggt
     1141 tcaaggtttg ttcacgttcg tcattacctc cgccgagacc gactccacgt tgacgtccaa
     1201 cagcatcaat ttcatcgata aagatgatag ctggtgctgc ttttttggca tcctcaaaaa
     1261 gagagcgaac acgactagct ccaactccga caaacatttc tacaaagtca gaacctgaga
     1321 tactaaagaa tggaacacct gcttctccag cgactgcctt agcaagcaaa gtcttacctg
     1381 tccccggagg tccctccaaa agaacacctg ctggaatacg ggctccaagt tttgtgaatc
     1441 gttttggatc ttttaagaac tcaacaactt caactagttc ttgtttttct tcctcagctc
     1501 cagcaacatc tgaaaatctt actttaatat cttctttatt tgctgcttta gccttactac
     1561 gtccaaaact cattggatta cggccattgc ctcctcccat atttcccatc atagagaata
     1621 ggaagaagaa tagaattcca aatggcacaa tggatacgag tagattaatc catataccac
     1681 ttgaactttc atgcttaaca gttacttctg ctttatggtc agtagcaagt ttttgcaatt
     1741 ctgatacggt agtatctgca ggaagaatag tgctggtaaa tttctctacc ttagtaacag
     1801 atggcgtgaa aaactgaata cctgttcctt ctttacttgt tttaggattt ttatagacac
     1861 cagaaacttc gataacacta ccatttggtt ggtaagttaa ttcttttaca ttaccatcgg
     1921 taatttcttg taccaactca gtatagttga tttgctgact tcctcctgag ttattcccag
     1981 aatagaaata ctggaatcct gtcacaagga aaaagataaa taataaccat agaaaaggat
     2041 ttttaattaa accattattt tgttttttca ttaaagatta ttctttctaa tttgaataca
     2101 cttcctcttt caatactcca atataaggaa gattacgata attttctttg tagtctaaac
     2161 cataacctac tacaaactca tttgggatag taaagcaggt atagtctgcc tcaatttcta
     2221 caacacgtcc ttctggttta tccaacaagg ttgcaatttt aacagaagct gcttctcttt
     2281 ctttaaacat atctcgcaaa ttcttcaaag tttgacctgt atcaatgata tcttctacaa
     2341 atagaacatg tcttcctttg atatcttgag tcacatcttg tttaatattg ataacaccac
     2401 tacttgctgt tccaccatgg tagctagaaa ccatcatgaa gtccatttca atatgtgtat
     2461 caatatgttt gaccaattca gccataaaag gaatagatcc ttttaaaatc ccaactaaga
     2521 ttggattttt tcctgcatag tctttagtta attgagcacc tagtttttta gctgcttctg
     2581 taatttcatc gtgtgaaacg aggacttttt taatatcgtt ttctaacatt ttttacctat
     2641 ctattttttc tatataaagt acagtgttca ttatatcatt tttcgttttt ttactcaaat
     2701 tattggtcgc aattcccaaa attgagacaa tttcaccaaa ttgctcaata ataagagcag
     2761 agtttctctt ttccataggg attttcaaat caataaataa acgtctgagt ttttttctat
     2821 gcccattttg aatcaaaaca tctcctgttt ttcgatgacg aatgtgtatg gatgtttcac
     2881 gtgaaacagg tatttgttga attgattcac cttctaatgg aagtccaaag gaaaataaat
     2941 atccttgata agctacctga ttttgatagt gtaacacaag ttcatcttcc tcttcatcag
     3001 cctgcggact gattttacaa atctgaaact gttggtactc ttttatcaat tcatagccat
     3061 ttttaatcgg atgacgatac tggcttttag attttaaaat ctgctgaact tcagcaaact
     3121 gagcttttgt aagattcaaa tctggaaaac gattcagata agtttgaagt aaaactcttt
     3181 gtgtagactc agagtaagaa aataactgct gtaaatcttc cacattaata ttgttagata
     3241 attcagctat tgccaaatca taatctaaaa tttcattgcc gatgcctaag attgcatccc
     3301 taaatcgagg attttctttt tccaattctg gtaagtaaga atttcgaata cgatttcgaa
     3361 aataatgatt ctcctgattt gatgtatctt caaagtgaaa aattgatgga aagtcttttt
     3421 tctgaaaatg caagaaggga cgaatgattt ctatctctcc gactacttgc ttctccttaa
     3481 ttcctgatag atagcgcaag cgagttcctc gaatcaagcg catcaaaatc gtttccacct
     3541 gatcatcagc atggtgggca gtgactaaag ctgtcgcacc tgtctttttc atgacctctt
     3601 gaaaaaaatc ataacgaaaa tttcgtgcac gcgcttctga aaattctcct gaaaaattgc
     3661 tgatataaat aggaagctct gcttcagcag ccaacttcct taattccttt tcttcccaat
     3721 ctgattcaat tctctgctta tgattcacat gagctagaat caattcaatc tctaactctt
     3781 tttgataagt agacaatacc ttaaatagaa acatggaatc taatccacca gaaagagcta
     3841 gaaccgcctt agcatgcttt ttgaaatatc ccttcttgag aaaatgattt aaaaaatctg
     3901 gttccctcat tttagaacct cataaacatc cttggctatc ttagaaatcg tatcataatc
     3961 agaattctta gtgaaaatag aaagaataaa tggagaatct gcatagacaa cacccgtatc
     4021 atgcttaaat tcatccgcat ctccaatttt atgagctact ttaacagaaa cacctttggc
     4081 aattcgctga ctatcaaaat ctgttttagt caaagactct agcacaaatc cattttgatt
     4141 ataaatagct tccataaact tcccggccat cttagaagaa atcaattttt cttttggatc
     4201 ccaatcatct cccataatgg cagacatctt ggatttgaat gtggcatcag attggtttga
     4261 aatgtaatat cccaatagat tatgagctac attatcagat tcttttgata ctttcgtaat
     4321 taaatccttt aaagaatatt ctttattatc ttctttttta ggaagactac cacttccctc
     4381 tggtttataa gaacctggaa aatcattgac tgcagatacg tattttacag tcgtatctaa
     4441 ctgataaaga ccctcattta ttttttcttg cgtataatag agataggaga gtttcaaaac
     4501 gctggctgca tacatctttt catcttgatt gataccagct tcttttccag tagtcagttg
     4561 cttaacataa atagagaaag aatctttctg atatttttca gataacattt cttgaacttt
     4621 actcatccga ttatcttctt cagaagttga ttctttagct acccatccag cctgatcaat
     4681 atgtagaaat tctcttcctt ctacaaacat ggtcttgtcg attgatactt gcgaataagc
     4741 tgataaggat gatttcactt cttttaaatc ataaggacta ttgtacagtt taaagtcaga
     4801 ttctaaccat gcttttttta ttgttggagt tacctctgat tgatcatata aaaatcgttt
     4861 gtccgcagct ataaattgat gatttgatag cttaaatact ggaattcctt gtttatttaa
     4921 gcgccactcg gttatttgaa aacttgtttt gggagtcaat ttcccagatt ccactactaa
     4981 atcttcattc gcataaacag gaacctctcc ataaaccatg ggagaactta atttttctct
     5041 aaaataaata ccaaagtcag attgtgaaag gtaataaatt tctttcgaag tatggacgac
     5101 ttctttttct gtgctaacga cttttgaaat ggtcaaaaaa cttggtagca acaaaataat
     5161 taagaattta cgcattcttc ctttcctttt cttcttgtaa acgcaataat tgatttttat
     5221 cagccaattc ttccagcttt tcatctgaca aactcaaaaa ttgctctatt acgtctaata
     5281 aattttccat tttatcacct ttgaagcaag tcaggaatcg tataaacttt ttccctcgac
     5341 ttagaataat agtacttcgc tcgtgtatat ttagcagcat aatcttcatc tttcaacttg
     5401 gtagcaaatg ctgtctcctt atccttttca tcactcaaag tttgatactg agtttgcaag
     5461 tctgctaatt gctgacgtct ttggagtaat tgctgataac tctgcgctaa attaaaagtt
     5521 ggcaagataa ataatagcat aatcaaaatc aatacccctc ccataaaacg attccgtttt
     5581 tgtcgttctt tcatcaggta gcgacgacgt tggtattcat tttgaataaa agaattattc
     5641 aattgtacaa tatttttaga cattttcttc tacccgtgtt tcactgataa tttcatacat
     5701 tcctgctgca tcttcttttt ttgtactatc tttcatctct agtactttta caagcagcaa
     5761 cttattgcca aagcgaattt caacttggtc attaactttc aagtccgttg aacttttggc
     5821 caagattcca ttaaccttga ttctaccttt atctgctact tcctttgcga ctgtacgacg
     5881 cttgataatt cgcgatactt ttaaatattt atctaatctc atccttatta cctcaattta
     5941 ttattgtacc atttttatct atttttatct attttataga agaaaaatat caaatggaat
     6001 tttcttcctt aaactctttt atctctaata aactttctcc aaaaatcagc agaccttcta
     6061 aaatttcata atctttctta ttttggacat caaatacaag ctccattaat cccttattct
     6121 cagcgatgcc tgcttttaag ttcgttacgg ataaagcttt aaaataatct tgagctaaaa
     6181 acaatcgttg agtgactttt tcaaattgaa ttgtaatttt attatctttt ctttccacac
     6241 gttgaacaaa gaccttgtcc aagtatgatt taaccaaacc aatctctaaa agataggcta
     6301 ctacatctgg gtattctcca aaacggtcta tcaactcctc ttgtaactct tcataattga
     6361 cacggttgtc aatttgacga attttcttgt aaatttcaat cttatgtcgt tgatcagaaa
     6421 tataagtatc aggaagatag gcatcaattt gcaaaatcaa ctcagcattc cctttggttc
     6481 ttgtgttagc gttagcatta ccgtttcgtt tagcaatagc ttcctctaat aactgcgaat
     6541 acaattcaaa accaacagaa tcaatgaaac cagactggga ttttcctaaa agatttcctg
     6601 ctccacgaat cgaaagatct cgcattgcaa tcttaaagcc agagcccaat tctgtaaatc
     6661 ctttaatcgc ttctaatctc ttttcagaga cttcactgat tgatttttct ggacgataca
     6721 tgagataagc ataagcaata cgattactac gaccgactct tcctcttaac tgatataagg
     6781 ttgacaagcc catatggtcc gcattttcaa taaataaagt attagcattt ggaatgtcca
     6841 cccctgtctc aataatagta gtcgtcacca agatatcgta ttgtccctca ataaagtcta
     6901 atagagtatt ttccaactgg acttcactca ttcgaccatg aacatatcca atcgaagcct
     6961 ccggaatcaa ctcctgtaat tctgaaacct tctgaacaat tgtgtcaact ttgttgtaaa
     7021 gataataaac ttgacctcca cgctccattt cacgcaagac agcatcacga atgacactat
     7081 cattcttttc caaaacatag gtctgaacag gatagcgatt agtcggcgga gtttcaataa
     7141 cagataaatc tctgattccc agcatagaca tatggagggt acgagggatt ggcgtagcgg
     7201 tcaaggttag gacatccact tgtttcttca gttctttcaa agtttcctta tgcttgacac
     7261 caaatcgctg ttcctcatca ataatcatca agcccaaatc agcaaacaca acatcttttg
     7321 acaaaacacg atgtgttcca atcaaaatat cgacttgacc gtttttcaat ttttcaagtg
     7381 ttgcagtctg ctctttttta cttctaaagc gactcaacac atcaatatta actgaaaaat
     7441 tttggaatcg ttccttaaaa ttcgtatagt gctgttgcgc taaaaccgtc gtcggaacta
     7501 gaatgacaac ctgtttgtga tcattgactg ctttaaaggc tgcacgcata gcaacttcag
     7561 tctttccaaa accaacatcc ccaactaaaa gtcgatccat tggctgagaa gcctgcatat
     7621 ccctcttgat ttcctcaata ctacgaagtt gatcatccgt ttcaacataa gggaaagcat
     7681 catcaaaggc atcttgatca tcatcatcag ctgagaaagc aaaacccttc aactgactac
     7741 gttcagagta gagtttgatt aaatcatcag ctatatcctc tacctggttc ttaacctttt
     7801 gcttggcctt tttaaaatga ccgtcattta atttattgag ttttggagct ttaccatcac
     7861 ttgaaatata tttggacagt agatgaatct gttccacggg gatagaaatt tgatcaccat
     7921 tttggtattg gacactgaca taatcgcgat gaattccctt gatttcaatg gtttcaattc
     7981 ctagatattg accaatccca tggatatgat ggacaacata gtcccctttt tcaagttcat
     8041 tgtaatcttt taatctctct gcatttgaaa catgttgtct tcgaaaacga cgctttaatt
     8101 tcttttgaaa aatctcatgt tcagttatca ataaaatctt ttcatctaca aaatgaaaac
     8161 catgtctgag attaccctct attaaattta cagattcttt acagatactt gtcttatctc
     8221 tagaatccaa tttaatctga tattcctcta acatatcctc caatgtttta cttcccattg
     8281 aattgctaga ctgcagaata atggtgtaat ccattttttt atatcgttca atttcttctt
     8341 ttagaaaaga aaactgattg aaaaattcct gtataggata ttgattgaat tgataaattt
     8401 tgtcaaattt gagatttcct aaaccctttt gaagattaga gaaaaaggtc actggacttt
     8461 gttttttata gatttgttca atatcagaaa aatactgcat atcagaaaat gctttactat
     8521 tctgtaattc ttctgtaaag tactgcgcta attctctttc aaagacttca tactgattca
     8581 tcaatttttg ataatcatca aagaatattg gagtatcttt ttcaatataa tcaaagacag
     8641 tccatgtctt atcatagcac aaagataaaa acttccgaga atctgcatga ctttgttttt
     8701 ggtgaaaact tgaaagaatt tcttctaggt atgatttcaa aataggtgat aaagtttttg
     8761 aaatttgttt ttctaaagct gactgtcctc gttgataatc cttttctctc aaaagcatat
     8821 cactagctgg aaagatagtg agttctgtct tattttcttt cgataattgt gtttctactt
     8881 caaatgacct gataccatca atttcatcac caaaaaactc aattcgacaa ggttctaact
     8941 gggatatttc aaaaatatct aaaatatctc ctcgaagact aaattcgccc tgagtttgta
     9001 cttgagtaac ttttcgatag ccattttcct ttaactgatg gataaacgcg tgttgagcat
     9061 attcttcacc aactgagatt tttacaatac tatctttgaa tgcattggga gacggtaaaa
     9121 tcaatcgact tgctgcgata ttacaaacta aaatcccttt cttagatgaa tcagtcaaaa
     9181 aacgcaaggc ttcaacccgt gaaataattt tttcctgtga agacatcaaa aactccacca
     9241 taggagcatc atctaccaaa aatggataga cgagttcctc acccaagata gaaataagat
     9301 cactaacaag tccttctgct tctccataag ttgacgtcaa taacacaatc ctatcttctt
     9361 tttctaaact gcttgcaatt gcaagagcct tagtagatgt tgataaacca agtattagtt
     9421 gtcttttctt atctgttaaa ttttgatgcc attttttaat ctgatcattt tctgagaata
     9481 aatctaataa ggtcaccatt tatccgttat acctctgcat tgttttctca aaatttttct
     9541 cttgtaaata gtagtttaca gaatcgtcaa ctttgtcaac agactgtaaa ataccgatat
     9601 aatcatccct gtcaaactta ctcaaaacat gatgaacaac tgacatacca tttttaggtc
     9661 ttccaattcc aatcttaaca cggttaaaga cctgagttcc tatatgttga ataatagact
     9721 tgataccatt atgaccacct gctgagcctt ttgctcttaa acgaattttc ccaacttcca
     9781 tgtcaagatc atcgtaaatg ataagtaaat cgtcaatatc caaaccatag taagttaata
     9841 aagcatgaac tgcttttcca ctttcattca taaaggtcgt tggtttaacc agataaattt
     9901 tttctccatt taggaaaaag gatgctaggt cagcttgaaa tatcttatcg tgtgtaaaag
     9961 tgacattctg tttcttcgct agttgatcaa tcaacataaa accaacattg tgttttgttt
    10021 caaaatattt atcccctgga tttcccaaac ctacaagtaa tttggtcatt tatttttcct
    10081 ttcaaaagcc aaaagggttg gaattttttt ccaacctaat tgacaccatt tattaatttt
    10141 tagacattaa agcggaattc catgatgtcg ccatcttgaa cgatatattc ttttccttct
    10201 tcacgcaagc gtccagcttc ttttacggcc ttttcagatc cgtatttcac tagatcttca
    10261 tatgacatgg ttactgcacg aataaagcct ttttcaaagt ctgagtggat aataccagct
    10321 gcttgaggag ccttcatacc acgtttgaaa gtccaagcgc gaacttcttt ttcaccagct
    10381 gtgaagtaag ttcccaatcc aagcaagtgg taagctgcac gcgtcaactt atctacacct
    10441 gattctgtca aaccaatggc ttcaagaaac tcttttttat cttcatcatc caattcagaa
    10501 atttcttcct cagcacgcgc agaaataacg actacttcag cattttctgt cgctgcaaat
    10561 tcacgaattt gtttgacata gtcgatagag tcaggttctg aaaccacatc ctcgtccaca
    10621 ttagctacat aaagaactgg tttagtcgtc aaaaggaaaa gacctttgac aaccttttgt
    10681 tcctcatctg taaattcaat ggtacgagct gatttcccgt cttctaggac tggtttaatc
    10741 ttttgaagaa cattgaattc tgctactgat tctttatctt tttgcgtacg tgccatcttt
    10801 tctacacgcg catatcgttt gttcactgat tctaagtcag caagaattaa ttccagatta
    10861 attgtatcaa tatctgcaag tggatctaca aaggcgtctt cacgtccttg ctcgcgcatc
    10921 acattttcat catcaaaagc acgaactacg tgaacaatcg catctacttc acgaatattg
    10981 gccaagaatt tattccctag cccttctcct tttgaagctc cttttacaat ccctgcaata
    11041 tccgtaaatt caaatgttgt gggaactgtc tttttaggag ttatcatttc agttagtttt
    11101 tgtaggcgtt catctggaac ttccaccatt ccaacatttg gatcaatcgt cgcaaatggg
    11161 tagtttgctg cctctgctcc tgcttttgta attgcattaa atagtgttga tttaccaacg
    11221 tttggcaaac caacgatacc tgctgtcaaa gccatatttc tcattctccg ttttcatttc
    11281 aatccctaat attataacac aaaaagggat aaagtgctaa ccctctaact aagggttctc
    11341 agtcaataat tttattcatt tttcgctcaa aatcatatcg ccccatcatg acaacatgct
    11401 cacaattact gcattttatt ttgatatctg ctcctacacg tgtaatttcc caacgattag
    11461 cctttttacc agtcgacttg attgtacaag cgtgtgattt tttcatctca acaaaatttc
    11521 caacttgata catactactc tccttttctt tttcgattat atcataaaag aggcgagcca
    11581 ggctcaacct ctttcactta atttgtacga actggtgtaa tgagctgcat gaagtcttcg
    11641 tcagtatctg ctggcacaag agtaaatgga cgaacagctg agataaagct aatggtcacc
    11701 ttttcgctat ttaaagcttt aagagaatca atcaagtaag ttgggttgaa actaatggtc
    11761 aaatcttcac cagtaacctg atcagtatcg atttcttcgt ttactttacc aacttctgga
    11821 gagtgaacat gggcgctaac aaccccatcc ttaatttcaa gtttcacagt accattttga
    11881 gtcgcacttg ataaaagacg ggcacgctcc attgactggc gtaagtttac cacattaaaa
    11941 gtaatagtag tgttaaagtc tgttggaatc aagcgatctg tatcaggata gtttccttct
    12001 aggagacgag tatagaagct aatattttcg cttctaaaga ggatttggtt attggcaaag
    12061 aaaatctcta cagtttcgat atcatctgta aataccgctg aaaattcgcg tagagaacgg
    12121 ctaggaatta cgacatcaaa atcatcacta tttttttcaa gagtcaattt tttctggctt
    12181 aggcgatgag agtctgttgc aactgttttt aactctttgt gttgactcaa tacgaagtgg
    12241 acacctgtta aaatcggacg actctcttgt gtacttgcag caaaggctgt ttcattaata
    12301 attttcttga gtaattttgt ttcaagtatt aaaggagtgc ttgctgaaat ttcttggatt
    12361 cgtggatatt gttcgctatc ttttcctttt agggtaattt ctgatttgcc actggttaaa
    12421 acaatttgat tttgttcaat ttctttaaaa tcaagagtta catcaggtaa actagatact
    12481 acattgataa agaaagaagc ttcaagaagg atcgaaccta aagaagtaat taacaaacca
    12541 gcatcttcat ttttttgaga aataaaattt tcaattgaaa tttgaccatt tgaaccaatt
    12601 aaagtaatac cttcattggt cacgtcaatt tttactgttg ataaaatagg aatggcattt
    12661 ttagaactaa tagctctctt agtagtattt aatgcttgta gaaataaatt tttattaatt
    12721 gaaaaatgaa tcatggattc tcctttattt atttttagta ttagaaagat aatagtaata
    12781 atagagtctg tgaaatctgt ggaaaacagc ctttaaacaa gtcatatcaa gttttttagc
    12841 ttgtttaaaa aatgtggata aaaaagataa aaaactaaaa gttatccaca aattatttga
    12901 ttttcttttt gattgattca atttctaaac gtaaattatc gtcttgatca atcaaagatt
    12961 ttattttggc atgggcatga atgactgtgg tatgatcttt tcccccaaat tccttcccaa
    13021 tttttggaag actattatct gttagttctc tagataaata catggctact tgacgggcca
    13081 aaacaatatt ttgaaggcgt ctacttccct tcatttcttt gatactaaca ccataaaagt
    13141 taccaacttc agtttggatt ttatcaattg ggatgacgag catttggcta acatcttgtt
    13201 tgcgggctct aatggcttct gcagcaatat caatagtgat atccttgatt ttttttactc
    13261 tggcaattaa agtgatgtcg ttgatggctc cctcaagatc tcgaacattt gaatcaaatt
    13321 gcccagctag gtattctaga gtatcacttt ggaaattgta gcctaaatgt tccgttttac
    13381 tttgtaaaat ggcaatacgt gtttcaaagt cagggggtgt gatagtttgt gtcaatcccc
    13441 aactaaaacg cgtgacaagc ctctcctcga gcccttctag atgttttgga ctacgatcac
    13501 tcgttaggac aatctgtttt tgcttgtcat gaagggcgtt aaaggtattg aaaaattctt
    13561 cctgagttgc gacttttttt ccgctgagtg actggatatc atcgattaac aaaagatcaa
    13621 gactacgata ggtcttttta aacttttcca tttccccaag tcttaggtga tcaagaaagt
    13681 cattaataaa gctttcggca gggatatatt taacacgcgc attaggaata ttttttagaa
    13741 tttcatttcc aatagcgttt aataagtgag tcttaccaag gcctggtcct ccatagataa
    13801 aaagagggtt ataggtcaga gccaaatctt cagagacagc taaagcggct gacacagccc
    13861 aaacatttcc atccccttga ataaagttat caaaggtata cttttctttt aatcccgtat
    13921 ctgaataagg aatagatact aactttggac tatagttata aagagttaaa tttgtagctt
    13981 cttcaacttg tgagctagtc gtatcttgag gtttggtgaa aatatagtgg ggagttattt
    14041 cagcgtcata aatttcaaaa ccagctacta caataatatc ttttagttgt ttttcccaga
    14101 ccatttccat ttcagagcga ggtagaaata tagtggcaac attttcctct accttgatga
    14161 gttcagcttg aatagcatag aaatcataca tggatcgagt cagtctttct tgtgcaaatt
    14221 ctaatatacg attccaaaat tgtttttctt tcaatccttt ctcctccttt actatttaaa
    14281 agtttaatac tagagatatt ttaccataga tagcaagaat tttccacaag ctgtgaaaaa
    14341 taatccacaa tgttaccaaa ctttatccac aggttgggga taaaagaaga aattattgat
    14401 ttattaagct ttttattgaa aaacatagtg gataaccttg tgagataaaa aaataaaaga
    14461 acagccttat ttcaggctgt tgataattct actatattct tcttgatttg aaaaagaaat
    14521 aatgattttt ccactgtctt ttttagatag tttaatttct acatctaatc cgagtagttt
    14581 tcttaactgt ttttcatcat tttgtatgaa atgattagtt ttttgctgtt tcttttgttt
    14641 tttctctgtc agaagagctt ctaatttcct tacagaaata tcttcttcta taatccgttg
    14701 aaagaaatag tcttgttgtt ccttatttaa cccaactagg gaacgcgcat gggcttgtga
    14761 tagtttgcca ttttctactt ctgaaagaat ctgttctggc aaggaaagta aacgaatgga
    14821 gttgctgata tatggacgag acttgcccat cttatctgca atttcagcat gggtgaatcc
    14881 tttctctacg agagattcat aggcgcgtgc ttcttctatt gggtttaaat tttctctctg
    14941 taaattttca ataatggact ggaccatcat ctcttggtct gaaatctgtt taacaacagc
    15001 tgggatagac cgtagaccag ctaaaagtga agcccgatag cgtctctctc ctgcaaggat
    15061 ttcataacca ataacaggag attgacgaac aataatcggt tgaatgaccc cattttcttt
    15121 gatagactgt gctagttcat ctagtttttc tctatcaaat tcttttcggg gttgataggg
    15181 atttttttgt atatctgtga tagaaatcat ttcaaatttt tccatgattc tacactaaca
    15241 catcttttct cttatgtaaa gctttcttta catagatgtc aattaagatt ctaaatcacc
    15301 tgaactcttg ttaagtttga tagaggtagt ttcttctttc ccgttacgat agtaggttat
    15361 cttaatggtg tctccgatag aatggttgta aagagcactt tgtaagtctg ttgatgaagc
    15421 aatctctttg tcatctactt ttgtaattac atcgtatttt tcaaggtgac cattggcagg
    15481 catattactt tgtaccgaac gaacaactac accagatgta acattacttg gaatattgag
    15541 tcttctgatg tcgcttgtac tcacattaga taaattaacc atctggattc ccaaagctgg
    15601 acgcgtcact tttccgtttt tttctaactg ttcaataata ttgatagcat catttgcagg
    15661 aattgcgaaa ccaagacctt ctacagatgt tcctccattt gtagcaattt tacttgaggt
    15721 aattccgata acctgccctt gaatattgat cagtgggccg ccagagttac ctgggttaat
    15781 agcagtatca gtttggatgg cttttgtaga aatagcttgt ccatcttccg attttaagga
    15841 tacatttcta ttgagactgg atacgatacc ttgagtgaca gtatttgcat attcagaacc
    15901 taacgggcta ccgatggcaa tagcagtttc tcctacagtt aacttactag aatcaccaaa
    15961 ctcagctact gttgtcactt tttctgaaga gatttttacg acagcaatat cagagaaagt
    16021 gtcagctccg acaatttctc caggtacttt agtcccatct gacaatcgaa tatctacttt
    16081 gctggcgcca tttataacgt gattgttggt gacgatgtaa gcttctttat cattcttttt
    16141 ataaataact ccagatcctt cactagagat tcgctgagaa tctgtgtcag tatcatcatt
    16201 gccaaatacg ctattttgtc tgtttgccga ataagtaata acagaaacaa cagcatcttt
    16261 tactttgtta acagcctgtg ttgttgaatt ttcgttctta taggcagttt gtgtaatagt
    16321 actattgttg ttagagttgt ttacactact tttttgagtt agttgagtta ttgaaaaact
    16381 acccaaggct ccactaaaaa agctaatgac gataacgact aataattgaa accatttttt
    16441 gtaaaatgtt tttagatgtt tcatatttgc ctccatatgt ttgaattact gaaagtataa
    16501 actgactagc ttaattataa cttaaacaca aaagttttac acaaactgtg gataactctt
    16561 ttgaaactgt gattttctta attgaaatct attttttatt ttgtgaataa gatgtgaaaa
    16621 aatagagaat atgttagaat agagtcatga aaattaaagt tgtaacagtt gggaaactga
    16681 aagaaaagta tttaaaagat ggtatcgcag agtattcaaa acgaatttct agatttgcta
    16741 agtttgaaat gattgagtta tcagatgaaa aaacaccaga taaggccagt gaatcagaaa
    16801 atcaaaagat tttagaaata gaaggtcaga gaattttatc aaaaattgct gaccgtgatt
    16861 tcgttattgt gttagccatt gaagggaaaa ctttcttctc agaagaattt agtaagcagt
    16921 tagaagaaac ttctataaaa ggattttcta ctcttacttt tattattggg ggaagtttag
    16981 gattatcatc atctgtaaaa aatagagcca atctttctgt cagttttggt cgcctaacct
    17041 tgcctcatca gttaatgaga ctagttcttg ttgaacaaat ctatcgcgct tttacgattc
    17101 agcagggatt cccctaccat aaatagaaaa ttgactttta attgaatttt tggtagaata
    17161 attgtgttag gtctcatagc tcagctggat agagcattcg ccttctaagc gaacggtcgc
    17221 aggttcgaat cctgctggga tcaatataat agcaaagctg ggaattttcc tggctttttt
    17281 cttaaaaaag tacactttgg gagaaaaaaa tgacagttga gagaatttta tctaaaacga
    17341 aattccattt tgtataatgg tttttgtaag ttagcttaca agaaaaaaca ttttaggaga
    17401 ttttattatg aaaaacacag ttaaattgga acagtttgta gctttgaagg aaaaagactt
    17461 acaaaagatt aaaggtgggg agatgaggat ttcaagaatc atccttgatt ttcttttcct
    17521 acgaaaaaag taatgaaata aggagaaaga gtaatggatt tacttggatt tgggacagtt
    17581 attgttcatt ttttaattat tagtcacagt taccgtttaa tttgtaaagg tcgaataaat
    17641 agaaaagaat tatacgtttt tggtgcttat acattactaa ctgaaatagt acttgaattt
    17701 tccttttatc ttctatattt agataaaata gggattgaaa gatttttatt tcctttgggc
    17761 ttatattcct attttcgatg gatgaaacag tatgagaggg atagaggact attcctaagt
    17821 ttactactat ctcttttata tgagagcact cataactttc tgtccgtaac tttctcctct
    17881 ataacaggag ataattttgt tttacaatat catttcccat tctttttcgt tgtgacggtg
    17941 ttaacctatt ttgttacatt aaaaatcatt tattatttcc atttggaact agcctatttt
    18001 gacaaggact acctttatcc tttcttgaaa aaagtatttt ttgctttact attgctacat
    18061 attgtatctt tcgtttcaga tatggtaagt acgattaaac atttgaatag ttttggaagt
    18121 attttgtcat ctattgtctt tatctctctc cttttgacct tctttgcaat gaattctcat
    18181 aaagttcaaa tggagaaaga gattgctttg aagcagaaga aatttgaaca gaaacattta
    18241 cagaattaca cagatgaaat tgttggtctg tataatgaaa tccgtggttt tcgacatgat
    18301 tatgctggaa tgcttgtcag catgcagatg gcaattgaca gtggtaattt acaggaaatt
    18361 gacagaattt acaatgaagt tttagtcaaa gcaaatcata aattgcgttc agataagtac
    18421 acttactttg atttgaacaa catagaagac tcagctttac gaagtttggt tgctcagtca
    18481 attgtctatg ctcgaaataa tggtgtagag tttacactgg aagtaaaaga tacgattacc
    18541 aagcttccaa ttgaactatt ggatttggtt cgtatcatga gcgttttatt gaataatgct
    18601 gtcgaaggat cggctgatag ctataaaaag cagatggaag tagcagttat taagatggaa
    18661 actgaaacag ttatggtgat tcagaattca tgtaaaatga cgatgactcc ttcaggagat
    18721 ctatttgcct taggattctc cactaaggga agaaatcgcg gagtcggatt aaataatgtg
    18781 aaagaactac tagataagta caacaatatt attttagaaa cagagatgga aggcagtaca
    18841 tttagacaaa tcattagatt taagagggaa tttgaatgaa agttttaatt ttagaagatg
    18901 ttattgaaca tcaagtgaga ctagagagaa tattggatga aatttcgaaa gaatcgaata
    18961 ttccaatatc atacaagaca acgggaaaag tccgtgaatt tgaagaatac attgaaaatg
    19021 atgaagtaaa tcagctttat ttcctagata tcgatattca tggaattgag aaaaagggat
    19081 ttgaagtggc tcagctcatt cgtcattaca atccttacgc tattatcgtc tttatcacta
    19141 gtcgatcaga gtttgcgact ctaacctata aataccaggt atcagcccta gattttgttg
    19201 ataaggatat caatgatgag atgtttaaga agagaattga gcaaaatatc ttctacacga
    19261 agagtatgtt acttgaaaat gaagatgttg tagattattt cgactacaat tacaagggaa
    19321 atgatttaaa aattccttac catgatattt tgtatattga aacaacaggg gtatctcata
    19381 aattgcgcat tattggtaag aattttgcaa aagagtttta tggtaccatg acagatattc
    19441 aggaaaagga caaacatact cagcgatttt attctcctca caagtcattt ttggtaaata
    19501 taggcaatat cagagaaatt gatcgaaaaa acttagaaat tgttttctat gaagaccatc
    19561 gttgtcctat ttcaagatta aaaattagaa aattaaaaga tattttagag aaaaaatctc
    19621 aaaagtgatt gacaattagc aagaaattga tataatggtt atatctgcta cagatagaag
    19681 gtccgttggt caaggggtta agacaccgcc ttttcacggc ggtaacacgg gttcgaatcc
    19741 cgtacggact attttatccg ccatagctca gttggtagta gcgcatgact gttaatcatg
    19801 atgtcgtagg ttcgagtcct actggcggag tatagataaa agggaacaca gctgtgttcc
    19861 tctttttgta tcaatttgta tcaccaagca ttttcataag gaagtctgtt atttcttgag
    19921 aactttcttt ttttccatgt gcaatccaag tttggcagac accaaaaagt gcatgagtta
    19981 gatagatgct actatattct aattcagtgg tatttagatt cagttgcata aatcgctttt
    20041 gtaaatctat actgagcatg atatgaagtt tatttcgtaa gaaattttgg atttctttag
    20101 tcccattttc agaaagaagg gcagccagaa gtggttctga ctctagatat tcaaagactt
    20161 ctaaaatagc gtctcttttg tgatgagcat gtttttgaaa aatatattca aatgtatgga
    20221 atagtttgct ttgatagtgc tcaatcatat catacttatc cttatagtga gtatagaagc
    20281 tggaacgact aattccggct ttttctacta atttgacagt agaaatttta tcaaatggct
    20341 gttccatcag taattgtacc atagcatttt caatagttcg ctttgttttt aagcgtttgt
    20401 tactttcttg catatttcct ccttgtaaac aaattagact atatgtctaa aaatagattt
    20461 tttatcttgt aatttagatt ttttaatgta taatctatta tatcaaaatt ttagacaata
    20521 tgtttaaaaa aggagaaact atgtttaaag aatggaaagc aatttaaaaa aacaaccttt
    20581 attattgtca tgatcgggat ttctcttatt ccagctctgt acaatatcat atttttgtca
    20641 ttaatgtggg atccatatgg gcaattgtct gacttacctg tggcagttgt aaataatgat
    20701 aaagaggctt cctataatgg taatactatg gcaataggaa aagacatggt gtccaattta
    20761 aaagaaaata aaaccttgga ttttcatttt gtagatgaag aggaaggaaa gaagggattg
    20821 gaagatggcg attactatat ggtagtgact ttaccaagtg atttatctaa aaaaacaact
    20881 acattatcca atattcaatc gacagcagct tatcaatcat tgacaagtga gcaacaaact
    20941 gggataagtg attctgtatc tcaaaattca actgatagta ttcaatcggc tcagtcaatt
    21001 gtagctttag tacaaggttt acagggaagt ttagaaaact tacaaaatca atcttctaat
    21061 ctttcgactt taaaaaatca agctaatcaa gtattaccta ttacttctac ttctttgata
    21121 ggattgtcaa gtggattaac agagatacaa ggagctgtta ctagcaaatt agttcctgcc
    21181 agtcagttga ttgcatcagg tgtaaacgca tatactacag gtgttgataa agtttctcag
    21241 ggcgcaagtc aactaagtga aaaaaatgcc accttgacac aaaaatcttc tagattgaca
    21301 gcaggagttg ataaattaca atcaggatct gggcaattag cagacaaatc cagtcagtta
    21361 ctttcaggtg cttcttcatt agagaatgga gctaataaat tggcagatgg atctgggaaa
    21421 ctagcagaag gtggaacaaa gttaacttct ggattggaag atttacagac aggacttgct
    21481 tctttaggac aaggactagg taatgctagt gatcaactca aatcagtatc aacagaatct
    21541 aaaaatgcag agattttgtc aaatccactc aatctttcaa aaagcagaca atgatcaagt
    21601 tcttgtaaat ggaatcgcaa tagctcctta tatgatatca gttgctcttt ttgttgcagc
    21661 aatatcaaca aatatgatat tttcgaaatt gccttcagga cgtcatccag agatccgttg
    21721 ggcttggttg aaatctcgag ctgaaataaa tggtattata gctgttttgg caggaatttt
    21781 ggtatatgga ggagttcatc ttattggttt aactgctaat catgagatga gaatatttat
    21841 tctcatcatc ctaacaagtt tagtattcat gtctatggtg accactttaa caacgtggaa
    21901 tagccgtata ggagctttct tctcacttat tttgctttta ctacagttag catcaagtgc
    21961 aggtacttat ccacttgctt tgacaaatga tttctttaaa tctattaatc cctggttacc
    22021 aatgagctat tcagtttcgg gattacgaca aacaatctcc atcaacaagt cattttccta
    22081 gctgtcatac tagctctatt tactggttta ggtatactag cctatcaaca taagaaaatg
    22141 gaagaagatt aaaaaaatcg accgattaac tggtcgattt tttatgcctt agatgacttt
    22201 cgtctgtgat tatagattcc aaatagtaag agagaagtaa aggaacagat tgctccagta
    22261 ataaaaccat tgggaatgaa ggaaagtgta atagttcctt tccccttggg aatgtcaact
    22321 ttcataaatc cagtttgagc ttgtttaatt tctattttct taccatcttg gtaggcagac
    22381 caacctttgt cataaggaat ggtgaagaaa atagatgtat cttgttggac atcatatgta
    22441 gcaaaaacct tgtttttaga agttgatact gtgacaggtt gttctttaat tttttgaatt
    22501 gcctcggtga aagttttggt atctaaacga tagaaggtag gagattcaaa tgatacttgt
    22561 gaatttccag ggaaactaac attgatattg aaagtttttt tctctttagt atatcctaga
    22621 ttaaagaagg agaagacatt atcagttgta aaagtctttt tttcaccatt tacaaggatg
    22681 tcaaccttct tttgtttatc gttagaaaag tgaaggttta tgaaagagag ataaacttgg
    22741 ctgttttctg gaacttcaat ttgatactgg attgctgcat cttcatttga agaacttgtg
    22801 acactaatca aatcattagt attttctatt ttttctgttt tttcataagg tattggagaa
    22861 aaataatcaa aattgacgtt agcaagttga tttaaaaatg aggcctgatt atccaaggta
    22921 tgttcattga acttgacatc attgtaaaca gattgactag caactgcaat cggaagagag
    22981 tattgatttt catatagggt aagattatct ttttgataga tatctttaaa gccatactta
    23041 tcaataggac tgtctgagat attgtactgg ataccaaata aactatcagc caaaatacta
    23101 ttatttgcat atcggagatt gagattagtc ccagaggatt taaaaccaag tttatctaaa
    23161 gtagagcttg atgaacgatt tcgaacagat gaaaattgag agattccatt gtagttgaat
    23221 ttcatactgt catttcctgt ctgagtttgt agtttttcag tacgagtaaa ttgatttcca
    23281 atatatgttg agaaagattc catagctggg atatctcgac tataagcact tcgagaagca
    23341 aatccccatt ccttagcaat tccgtccatt tgagatgaag catttaaact catttcaacc
    23401 agtataaata aagagattag aatggcaaat agattcacag atataaactt tttgataact
    23461 gcaaggagta aaagagaata gacaaccaaa aattcaagag taagcagaat attcaaatct
    23521 gttaaaaaag aataatgcga ttttagatag atggtagcta aaaatcctgt tactacaaga
    23581 aaaagcgaaa ctaaaaaatt ccagacttta agttctttca gacgctttaa gacttctgct
    23641 gctgtgtaaa ttaacaaggt agagaaaatc caagcatagc gatgtaaaaa catgtttgga
    23701 gtatgcatgc cttgccaaaa taagtcaaga gcttctatgt aaaagcttgc aattagaaat
    23761 gcaaagaata ttatatatat gagtttcacg tgaaacttaa tagatttcag cgtaaaaaat
    23821 aaaatggtca aaataaaggg aagtagtcca acaaaaatca ttgggatggc cccatacttt
    23881 gttgtgtcaa aggaaccaat gaattgctta gcaaagagat caagatacca gctactttca
    23941 gtttgaaact ttgtaacttc agtcaatttt tccccatgtg tctgtaaatc aaacagagtg
    24001 ggaagagtca taatcaaact agccatacca gctaaaaagg agataactat gaaatcaaga
    24061 acagatgatt ttcgagtctt aaagtcccac gaaatttgac agagatacca gaaaataaga
    24121 aacaatactg tcatatatcc aaaataataa ttttgaataa ataagattga cagacttgta
    24181 aagtacaata ggagtttctt ttcagttatc agtagatgta aaccagttat aattaaagga
    24241 atcaagataa aaacatctag ccaggttttt atctctaatt gactgacagt gaaactcatc
    24301 agagcatagg aagtagataa ggctagtttt aaagtctgag ggatagattg aaacaattta
    24361 ttcaaactaa aaaaggttga cagaccaatc aatccaaatt ttaagagagt ggtcagatag
    24421 acagcatctg gcatattcgt tagatcaaaa aagtaaacta gaggcgcgag aaaactaccc
    24481 aagtaataac tagatagggc atagaagttt agccctagac cacttgtaaa ggtgtaaaac
    24541 agactactat ttccatgtag gatatttcgt aaggctacat caaaaataac gtattgatga
    24601 aagccatctc ctaatagagg agagttgtcg ctattccagt agataccttg agatagatat
    24661 actccagaca taatcactac aggaatgatg aaagaaataa aataggttcg atatgttttt
    24721 aaaaatgatt tcatgttacc tcgtagaatg atagaaaact cagttggtta acccaactga
    24781 gttttgaagt tttatttagt ctttccaaag ttctttaact tttgcttgta cttctgcatt
    24841 ttctaggaat tcatcgtagg tttcatcgat acggtcaatg acgccatttt tagataagac
    24901 aatgatatgg ttagccaaag tttgaataaa ttcgtggtca tggctagcaa agatgattga
    24961 ttctttaaag tttttcaatc catcattcaa gcttgagata gattccaagt ccaagtgatt
    25021 tgttggatca tcaagtacaa ggacatttga ttttaagagc atgagttttg aaagcatgac
    25081 acgaactttt tctccccctg acaagacatt tacaggtttg ttaacttcat ctccagagaa
    25141 gagcatacgg ccgaggaaac cacgtaggaa agtattgtca tcttcttctt tacttgcgaa
    25201 ttgacgcaac cagtcaagaa ttgattctcc tcctgcaaaa tcagctgagt tatcttttgg
    25261 taggtaagat tgactagttg taactcccca cttgacagtt ccttcatagt caatatctcc
    25321 catgattgca cgaattaatg cagttgtttg aatatcattt tgtccaataa gtgctgtctt
    25381 atcatctgga cgcaagatga aactaatatt atccaagata gtttcaccat caatctttac
    25441 agttagattt tctactgtca agagatcatt accaatctca cgttccgctt taaagttgat
    25501 aaatggatat ttacgactag atggtacaat ctcttctagc tcaatcttat caagcatttt
    25561 cttacgtgat gttgcctgcc ttgacttaga agcattggca gagaaacgag caacgaattc
    25621 ttgcaattgt ttaatttttt cttctgcttt agcattacgg tctgctagca atttagcagc
    25681 aagctcagaa gattccttcc agaagtcgta gtttccgaca tagagtttga tttttccaaa
    25741 gtcaaggtcg gccatgtgag tacaaacttt gtttaagaag tgacggtcgt gggatactac
    25801 gataactgtg ttatcaaagt caattaagaa gtcttctaac caagtaatcg attggatatc
    25861 caaaccgtta gtaggctcgt ccaagagaag aacatctggt ttaccaaaaa gtgctttggc
    25921 gaggagaacc tttacttttt caccgttggc caattcgctc atgttttggt agtgtaattc
    25981 ttctggaatg tttaggtttt gaagtagttg agaggcttca ctctctgctt cccaacctcc
    26041 aagttcggca aactctcctt cgagttcggc agcacgaacc ccgtcctcgt ctgagaaatc
    26101 ttccttcatg tagatagcat ctttctcttt catgatgcta taaagttttt catttcccat
    26161 gataacgaca tcaatggcac gttcatcttc gtagtcaaag tgattttgac gaagaacaga
    26221 gagacgttca tctggaccaa gagagatgtg accagtagta ggttcgatat ctccagctaa
    26281 aatttttaaa aaggttgatt ttccggcacc attagcaccg attaatccgt aagtatttcc
    26341 ttctgtaaat ttgatattga catcatcaaa aagtttgcga tcactaaaac gtagtgaaac
    26401 atcagatact gtaagcaata tttttctcct atatgtgtaa tatatttatt ctactagaaa
    26461 atacagaaat attcaaattt ttatttgtca attttgtgta aattatattt acagtatcct
    26521 ttacacaaat ctgtaaaaag caaggctgat ttattttgat aaattacggt tatttcatta
    26581 aaaaaatgct ataattgaaa ggactatatc gaaggagaac aaaatgacta aacccattat
    26641 tttaacagga gaccgtccaa caggaaaatt gcatattgga cattatgttg gaagtctcaa
    26701 aaatcgagta ttattacagg aagaggataa gtatgatatg tttgtgttct tggctgacca
    26761 acaagccttg acagatcatg ccaaagatcc tcaaaccatt gtagagtcta tcggaaatgt
    26821 ggctttggat tatcttgcag ttggattgga tccaaataag tcaactattt ttattcaaag
    26881 ccagattcca gagttggctg agttgtctat gtattatatg aatctagttt cgttagcacg
    26941 tttggagcga aatccaacag tcaagacaga gatttctcag aaaggatttg gagaaagcat
    27001 tccgacagga ttcttggtct atccaatcgc tcaagcagct gatatcacag ctttcaaggc
    27061 taattatgtt cctgttggga cagatcagaa accaatgatt gagcaaactc gtgaaattgt
    27121 tcgttctttt aacaatgcat ataactgtga tgtcttggta gagccggaag gtatttatcc
    27181 agaaaatgag agagcagggc gtttgcctgg tttagatgga aatgctaaaa tgtctaaatc
    27241 actaaataat ggtatttatt tagctgatga tgcggatact ttgcgtaaaa aagtaatgag
    27301 tatgtataca gatccagatc atatccgcgt tgaggatcca ggtaagattg agggaaatat
    27361 ggttttccat tatctagatg tttttggtcg tccagaagat gctcaagaaa ttgctgatat
    27421 gaaagaacgt tatcaacgag gtggtcttgg tgatgtgaag accaagcgtt atctacttga
    27481 aatattagaa cgtgaactgg gtcctattcg tgagcgccgt attgaatttg ctaaggatat
    27541 gggagaagtt tataatatga ttcaaaaagg tagtgaaaga gcgcgtgaag ttgcgggtca
    27601 aaccctatct gaggtaaaag gggcaatggg acttcattac tttaactaag tttattttac
    27661 aagaaactat cttttctatc tcgaagaaaa gatagttttt tatttacccc tgtaacattt
    27721 gacaaatttt tatagaatgg tatgatagat acaatataaa aagagtcaag ctcaaaaaga
    27781 aagaaaagag gaaacttcga atgtctaatt gggacactaa atttttgaaa aaaggtttta
    27841 cctttgatga tgtattgctt attccagctg aaagtcatgt gttgcctaac gatgcagatt
    27901 taacaactaa attggcagat aatttgactt taaatatccc aattattacc gctgccatgg
    27961 acacagttac agagagtcaa atggccattg ctattgctcg tgcaggcggt ctcggagtta
    28021 tccataaaaa catgtcaatt gctcaacaag cagacgaggt tcgtaaggta aaacgttctg
    28081 aaaatggagt tattattgat ccgttcttct tgacgcctga acatacaatt gctgaagcag
    28141 atgagcttat gggtcgttac cgcatcagtg gtgttccagt tgttgaaaca cttgaaaatc
    28201 gtaaattggt tggtattttg acaaaccgag atcttcgttt tatttcagat tataatcaac
    28261 caatttcaaa ccatatgact agtgaaaatc ttgttactgc tcctgtgggt acggatcttg
    28321 caacggctga gagtattctt caagagcatc gtattgaaaa acttccgttg gtcgatgaag
    28381 aaggcagtct ttctggtttg atcactatca aagatattga aaaagttatt gagtttccaa
    28441 atgcggctaa agatgagttt ggtcgtcttc tagttgcagg tgcagtaggt gttacttcag
    28501 atacatttga acgtgcagag gctctttttg aggcaggagc ggatgcgatt gttattgata
    28561 ctgcacatgg tcattctgca ggtgtcttgc gtaaaattgc cgagattcgt gctcatttcc
    28621 cagatcggac tttgattgct ggaaatattg ctactgctga aggtgcacgt gccctttatg
    28681 aagcgggtgt agacgttgtt aaggttggta ttggaccagg ttctatctgt actactcgtg
    28741 tgattgctgg tgttggtgtt ccgcaagtaa cagctatcta cgatgctgca gctgttgcgc
    28801 gcgaatatgg taaaacgatt attgctgacg gtgggatcaa gtattctgga gatattgtaa
    28861 aagcacttgc tgcaggtgga aatgctgtta tgcttggatc tatgtttgct ggaactgatg
    28921 aagctccagg cgaaactgaa atcttccaag gacgtaaatt caagacttac cgtggtatgg
    28981 gatcaattgc tgctatgaag aaaggttcaa gcgaccgtta tttccaaggt tctgtcaatg
    29041 aagcaaacaa gcttgttcca gaaggaattg aaggtcgtgt tgcttataaa ggagcggcag
    29101 ctgatattgt tttccaaatg attggtggta ttcgctctgg tatgggttac tgtggtgcag
    29161 ctaaccttaa agaactacac gataatgctc aatttattga aatgtctggt gctggtttga
    29221 aagaaagcca tcctcatgat gtgcaaatta ctaatgaggc accaaattat tctatgtaaa
    29281 aaacaatgaa aagaactcca gtgaaaacag gagttctttt acaatgttgt caatctccat
    29341 ttacagcagc tttaccatcc tgaatagtga agatacttag attttctggc agattttgaa
    29401 gatggtctaa gcttgttgtt gtgataaagg tttggattga ttgagaaatc gtttctaata
    29461 attttaactg tctagtgttg tcaagttcac tcatcacatc gtcaagcagt aatataggag
    29521 attctgtggt aatgctttcc attaattcga tttctgctaa ttttatcgag aggacgagac
    29581 tacgatgttg accttggctt ccgaaactag catccatccc atttatataa aaagaaatgt
    29641 catctcgatg aggaccgaca ccagtattct ttttaaataa atctctggat ctactttttt
    29701 ctaaagcaat tttgaaagat tcggataagt tttgtttgtc agttatattg acagaagatt
    29761 gataggatat tgacaactct tcgatctgat tagagagttc aaaatgtttc ttacgcccaa
    29821 atgattctag tttttttatg aaatctaagc ggtgattcat tacacgacat ccataatcaa
    29881 ctagctgatc atctaacaca gaaaggaatg tttcatctat tttttgagct gattttaggt
    29941 aagtgtttct ttgctttagg atgtggttat aattggttaa gtcagataaa tagattggct
    30001 taatttgccc aagttccata tcaatgaatt ttcgtcgaat cgaaggtgct cctttaatta
    30061 gttgtaaatc ttcaggagca aataagacaa cattcatgtg tcctacataa tctgaaaggc
    30121 gtgcctgttt taagtgatta acttttgtta cacggccttt ttgtgttagt tcgatttcta
    30181 ggggaatgga tccagttttt ttctgaacga gacctgaaag atgaagttgt tcctcatcaa
    30241 aatgaatgag atttttatct gttcgagttc gatgactacg cgttaaggct aaaaaataga
    30301 tagcctctaa catgtttgtt tttccttgtg cattacgtcc caaaaagaca ttcaatttag
    30361 gattaaagtc tattttcgtt tctttgtaat tacgaaaagt cttgagagat agatgttgta
    30421 gccacatgat tatctaccag ggaatcgtgg agcttgttgg cttttaggtg atgaagcagg
    30481 tttcgatttg tcttttttaa ctcccttatt catctttttg acaagtttag cgatccgttc
    30541 tttttcaact ttatcagctt ggtattcatc ttgttcttca gaagtaggtt gtgtcaacaa
    30601 gatgtcaatg ttcatgtcag ggatgtcaac tttatcgcca atacgaagtt tttttccacg
    30661 ccgactctct aattccctat taaagtaaac agaatgttca gagagaaatg atttaatagc
    30721 tcctccgcta tgtgtaattc caagttcttt gagtagtgct tggagggtaa taaattcttc
    30781 aaataatttg tattccataa ttcacctcaa tctttggtat tataccatat tttcctaaaa
    30841 atagtgagag agacagcgag aaatgtaagc gatttttatt tcaaaagtgt tacaggaaac
    30901 aagaaaattt caggttttcg tgatataata gaagtctgta tataaggagg taaatcatgg
    30961 agttagtgca tggaatttca acacatttta tccaatcaaa aaagtttaaa acaaacaaaa
    31021 ttaccgtgcg ttttaccgct ccattatccc ttgatacgat tgcaggtcac atgttgagtg
    31081 caagtatgct agagactgct aatcagatgt gccccacttc tcaagatttg aggagacact
    31141 tggccagtct atacggtaca gatatgtcaa ccaattgttt cagaagaggg caaagccata
    31201 ttatagaatt gacatttacc tatgttcgtg atgagttttt aagtaggaaa aacgtgctaa
    31261 cctctcagat tttggaactt gtaaaagaaa ctcttttttc acccgtagta gttgataatg
    31321 ggtttgatcc ggccttattt gaaattgaga aaaaacaatt gctagcaagt ttagcagctg
    31381 atatggatga ttctttttat tttgcacata aagaattgga taaattgttt tttcatgatg
    31441 aacgtcttca attggaatat agtgatttac gaaatcgtat tttagctgaa actccacaaa
    31501 gttcttattc ttgtttccaa gaatttttag ccaatgatcg aatagatttc tttttcctag
    31561 gtgattttaa tgaggttgaa attcaaaatg tattagaatc atttggcttt aaaggtcgaa
    31621 aaggagatgt gaaggttcag tattgtcaac cttattctaa tatccttcag gaaggtatgg
    31681 ttcggaaaaa tgtgggacaa tccattttgg aattaggtta tcattaccgt tctaaatatg
    31741 gtgatgagca acatttaccc atgattgtaa tgaatggttt acttggtgga tttgctcact
    31801 ctaagctctt tacaaatgtc cgtgaaaatg ctggattagc ttataccatt tcaagtgagc
    31861 ttgatttatt tagtggattc ttgaggatgt atgctggtat caatcgagaa aatcgtaacc
    31921 aggctcgtaa aatgatgaat aatcaactgc ttgatttaaa aaaaggttat tttacagagt
    31981 ttgagttaaa tcagaccaag gaaatgattc gttggtcgtt gttactttct caagataatc
    32041 aatcttcatt gattgaacgt gcttatcaaa atgccttatt tggaaaatct tcagcagact
    32101 ttaaaggttg gattgcaaaa ctcgagcaag ttgacaaaga tgctatttgt agagcagcta
    32161 ataatgtgaa actacaggcg atttacttta tggaaggaat agaatgacaa aggttgtttt
    32221 tgaaaaaaaa tactatccag ctgtaaaaga aatgatttat cgaactcgtt tggccaacgg
    32281 attgacagtt gctcttttgc ctaaaaagga atttaaagag gtttacggga gtgtcactgt
    32341 acagtttggt tcggtagata cgtttgtcac agaagttgac ggagatgtaa aacaatatcc
    32401 tggaggaatt gctcattttc ttgaacataa attatttgag agagaagatt ctagtgattt
    32461 gatgtcggct tttacgagtc taggtgcaga tagtaatgcc tttacaagct ttacaaaaac
    32521 aaactatctt ttttcagcaa cggattattt tttagaaaat ttagatttac ttgatgaatt
    32581 ggtaacatca gcacacttta ctgaagcttc cattctgaca gagcaggata ttattcagca
    32641 agaacgagaa atgtaccaag atgatccaga ttcgtgttta ttcttttcaa ctttagcgaa
    32701 tttgtatcct ggtacacctt tagcaactga tatagttgga agtgaggagt ccatttccca
    32761 aatcaatcta actaatttgc aagaaaattt tacaaagttt tacaaacctg taaacatgtc
    32821 tctgttttta gttggtaatt ttgatgtgga gcgagtacag gactattttg aaagcaaaga
    32881 actgaaagat tcagattttc aggaagtagc aagagaaaag ttgtttttac agcctgtaaa
    32941 gccaacagat agtatgagaa tggaagtatc ttctcccaaa ctagcgattg gagttagagg
    33001 taagcgagaa gtttctgaag cggattgcta tcgacatcat attttattaa aattattgtt
    33061 tgcaatgatg tttggttgga cttcggatcg ttttcaaaaa tgttatgaat caggtaaaat
    33121 tgatgcgtcc ttatctctgg aagttgaaat aacaagtcgc tttcattttg tcatgttgac
    33181 aatggatacg aaagagccag ttgctttgtc tcatcaattt aggaaggcta ttcgtaattt
    33241 tacaaaggat ttagatatta cagaggaaca tttagatatt atcaaaagag agatgtttgg
    33301 cgaatttttc agtagcatga actctcttga atttattgca acgcaatatg atgcttttga
    33361 aaatggtgag acaatttttg atttgccgaa aattttacag gaaattactt tagaggatgt
    33421 ccttgatgct ggacatcatt taatagatga tggtgacata gttgatttta caatattccc
    33481 atcgtagtaa cctatcataa tagacactag aaagaaggga tgacaagtat gagaaaaaaa
    33541 acaattggag aggttttacg attagctaga atcaatcagg gattgagttt agatgaattg
    33601 cagaaaaaga cagaaatcca gttagatatg ttggaagcaa tggaagcaga cgatttcgat
    33661 caacttccaa gtccttttta cacgcgttct ttcttgaaaa aatatgcatg ggctgttgag
    33721 ttagatgacc aaattgtttt ggatgcttat gattctggga gtatgattac ttatgaggaa
    33781 gtagatgttg atgaagatga gttgacaggt cgtagacgtt caagtaagaa aaagaagaaa
    33841 aaaacatcat ttttaccttt attttatttt atcctttttg ctttatcgat tttaattttt
    33901 gttacttatt atgtttggaa ctatattcaa actcaaccag aggagccttc tctttctaat
    33961 tacagtgtgg ttcaatcaac aagttcaact agctctgttc cccactcctc aagtagtagt
    34021 tcttctagta tagaatcagc tataagtgta tcaggcgaag gaaatcatgt agaaatcgct
    34081 tataagacaa gtaaggaaac agttaaattg caattggcag tttcagatgt tacaagttgg
    34141 gtcagtgttt cagaaagcga acttgagggc ggtgtaacct tatcgccaaa gaagaaaagt
    34201 gcagaagcaa cagttgcaac taaaagtcct gtaacaatta cgttaggtgt tgtaaaaggt
    34261 gttgatttga cagtagataa tcagactgtt gatttatcga aattaacagc tcagactgga
    34321 caaatcactg taacctttac taaaaattaa ggaaaaacga atgaaaaaag aacaaattcc
    34381 caatctctta acaataggtc gaattctctt tatacctatt tttatcttta ttttaacgat
    34441 aggaaattcg atagagagtc atatagttgc agctattatc tttgctgttg ccagtattac
    34501 cgactattta gatggatatt tagctcgtaa atggaatgtg gtcagtaatt ttggtaaatt
    34561 tgcagatcct atggcggata agttactagt tatgtcggct tttattatct tgattgagtt
    34621 aggtatggct ccggcttgga ttgttgcagt gattatctgt cgtgagttag ctgtgacagg
    34681 tttaaggctt ttattggttg aaactggtgg aacaatttta gcagcagcaa tgcctggaaa
    34741 aattaaaact tttagtcaga tgtttgctat tattttcttg ctattacatt ggactttgct
    34801 tggtcaagtt ctactttatg tagccttatt tttcactatc tactctggct atgactattt
    34861 caagggtagt gcctatgtat ttaaagggac atttggttcg aaatgaaatc aataattgat
    34921 gtaaaaaatc tttcttttcg ctataaagaa aatcagaact actacgatgt gaaggatatt
    34981 acgtttcacg tgaaacgtgg agaatggctt tcgattgtag ggcataatgg tagtggtaaa
    35041 tcaactacgg ttcgattaat tgatggctta ctggaagcag aatccggaga gattgtaatt
    35101 gatggccaac gtttgactga ggaaaatgtt tggaatatac gtcgtcaaat cggtatggtt
    35161 tttcaaaatc cagacaatca atttgttgga gcgactgttg aagatgatgt tgcttttggt
    35221 ttggaaaatc agggactttc tcgtcaagaa atgaaaaaga gagtggaaga agctctggct
    35281 ttagttggca tgttggactt taaaaagaga gagccagcgc gtctatcagg tggccaaaag
    35341 caacgtgtgg ccattgcagg tgttgtagcc ctaagaccag ctattttaat cttagatgaa
    35401 gcaacgagta tgttggatcc tgaggggcgt agagaactta ttgggacagt aaaaggaatt
    35461 cgaaaagact atgatatgac ggtcatttct attacccatg atttggaaga agtcgccatg
    35521 agtgatcgcg tattggtcat gaaaaaaggg gaaattgaat caactagtag tccaagggag
    35581 cttttctctc gaaatgattt agatcaaatt ggattagacg atccttttgc taatcaatta
    35641 aaaaaatctt tgagccagaa tggctatgat ttacctgaaa attatttgac agaaagtgag
    35701 ctagaggata agctatggga attgctctag aaaatgtgaa ttttacatat caagaaggta
    35761 ctcccttagc tttagcagct ttgtcggatg tttctttgac gattgaagat ggctcttata
    35821 cagctttaat tgggcacaca ggtagtggta aatcaactat tttacaactc ttaaatggtt
    35881 tattggtgcc aagtcaaggg agtgtgaggg tttttgatac cttaatcacc tcgacttcta
    35941 aaaataaaga tattcgtcaa attagaaaac aggttggctt ggtatttcag tttgctgaaa
    36001 atcagatttt tgaagaaacg gttttgaagg acgttgcttt tggaccgcaa aattttggag
    36061 tttctgaaga agatgctgtg aagactgcgc gtgagaaact ggctctggtt ggaattgatg
    36121 aatcactttt tgatcgtagt ccgtttgagc tgtcaggggg acaaatgaga cgtgttgcca
    36181 ttgcaggcat acttgccatg gagccagcta tattagtctt agatgagcca acagctggtc
    36241 tagatcctct agggagaaaa gagttgatga ccctgttcaa aaaactccac cagtcaggga
    36301 tgaccatcgt cttggtaacg catttgatgg atgatgttgc tgaatatgca aatcaagtct
    36361 atgtaatgga aaagggacgt ttagtaaagg ggggcaaacc aagtgatgtc tttcaagacg
    36421 ttgtttttat ggaagaagtt cagttgggag tacctaaaat tacggccttt tgtaaacgat
    36481 tggctgatag aggcgtgtca tttaaacgat taccgattaa gatagaggag ttcaaggagt
    36541 cgctaaatgg atagtatgat tttggggcgt tatatcccag gggattcgat tgttcaccga
    36601 ttggatccac gtagcaaatt gcttgctatg atgctactga ttttgattgt gttttgggct
    36661 aataacccct tgacgaatct gattcttttt atagcgacag ggatatttat tgccttgtca
    36721 ggagtatctc tttcattttt tattcagggc ttgaagtcta tgtttttctt gattgccttc
    36781 acaactattt ttcaactatt tttcatttct aatgggaatg ttttatttga gttttcgttt
    36841 gtgagaatca cggattatgc tttgcaacaa gctgggatta ttttttgtcg ctttgtattg
    36901 attattttct tttcaacttt gttaacctta acaaccatgc ctttaagttt ggcatcagct
    36961 gtcgaagctt tattagcacc tttaaagcgt gtgaaagttc cagttcatga aattggattg
    37021 atgctgtcta tgagtttgcg ttttgtccca accttgatgg atgatacgac gcggattatg
    37081 aatgcacaga aagctcgtgg agtggatttt ggagaaggaa gcatcgttca aaaagtaaag
    37141 gcgatgattc ccattttgat tcctcttttt gcgacaagtt taaaacgtgc agattccttg
    37201 gctatcgcta tggaagcgcg tggctatcag ggtggaaaag gcagaagtca ataccgacaa
    37261 ttgaaatgga ctctaaagga tacgctgacc attcttgtta ttctcgtact tggttgttgt
    37321 ttatttttct taaaatctta gtagctttca ggaattgata aaaagttact gtaacagttt
    37381 ttgatataaa ggtagggata tgaaccgttt taaaaaatca aaatatgtca ttattgtttt
    37441 tgtcactgtt ctgcttgtgt cagctctttt agcgacgact tattcaagta caattgtgac
    37501 aaaattagga gatggaatct cattggttga tagagttgta caaaaacctt ttcagtggtt
    37561 tgattctgtc aaatcagatt tggctcattt gacacgaaca tataatgaaa atgaaagttt
    37621 gaagaaacag ctttaccaat tagaagttaa atcaaacgag gtggaaagtt taaagacaga
    37681 aaatgaacaa ctgcgccaat tgcttgatat gaagtctaaa ttgcaagcca caaagacttt
    37741 agcagcagat gttattatgc gttctccggt atcttggaag caggagttga ccttagatgc
    37801 aggtagatca aaaggtgctt ctgagaacat gttagctatt gcaaatggtg gcttgattgg
    37861 gagtgtttca aaagtagagg agaactctac tatagtcaac cttctgacaa atacggaaaa
    37921 tgctgataag atttctgtta aaattcaaca tggctctact acaatttatg gaattattat
    37981 tggctatgac aaggaaaatg acgttcttaa aattagccaa ttaaatagta atagcgatat
    38041 tagtgcggga gataaggtga ctactggtgg attaggaaac tttaacgttg ctgatattcc
    38101 tgttggtgaa gtggttgcca caacgcatag tacagactat ttgacacgag aagtaactgt
    38161 taaattgagt gcagatactc ataatgtaga tgtgatagaa ttagtgggga attcataatg
    38221 agacagttga agcgagttgg agtattttta ttgcttcctt tctttgttct aattgacgcc
    38281 catattagcc agcttctggg ctcatttttc ccccatgtac atttggctag tcattttctt
    38341 tttttatttc tcttatttga gacgatagaa gtatcagagt atctctacct agtctattgt
    38401 tttgttatag gcttggttta tgatgtttac tttttccatc taatagggat tacaactctc
    38461 ttatttatct tattgggagc cttccttcat aaattgaata gtgttatttt gttgaatcgt
    38521 tggacaagaa tgctagctat gattgtgctg acattcctgt ttgaaatggg tagttatctt
    38581 ttggctttta tggtagggtt gacagtagat agcatgtcga tttttatagt ctatagcttg
    38641 gtaccgacga tgattttaaa ttttttatgg attactgttt ttcaatttat ttttgaaaaa
    38701 tattatctat aagaacgaca tataaatgta acaaaggcgt aatatttatt aggccttttt
    38761 ttggtatact agtattgtct ttaaaagaag gagtatctac gtaatatgaa gaaaaaaatc
    38821 ttagcgtcac ttttattaag tacagtaatg gtttctcaag tagctgtttt aacaactgcg
    38881 catgcagaaa cgactgatga caaaattgct gctcaagata ataaaattag taacttaaca
    38941 gcacaacaac aagaagccca aaaacaagtt gaccaaattc aggagcaagt atcagctatt
    39001 caagctgagc agtctaactt gcaagctgaa aatgatagat tacaagcaga atctaagaaa
    39061 ctcgagggtg agattacaga actttctaaa aacattgttt ctcgtaacca atcgttggaa
    39121 aaacaagctc gtagtgctca aacaaatgga gccgtaacta gctatatcaa taccattgta
    39181 aactcaaaat caattacaga agctatttca cgtgttgctg caatgagtga aatcgtatct
    39241 gcaaacaaca aaatgttaga acaacaaaag gcagataaaa aagctatttc tgaaaaacaa
    39301 gtagcaaata atgatgctat caatactgta attgctaatc aacaaaaatt ggctgatgat
    39361 gctcaagcat tgactacgaa acaggcagaa ctaaaagctg ctgaattaag tcttgctgct
    39421 gagaaagcga cagctgaagg ggaaaaagca agtctattag agcaaaaagc agcagctgag
    39481 gcagaggctc gtgcagctgc ggtagcagaa gcagcttata aagaaaaacg agctagccaa
    39541 caacaatcag tacttgcttc agcaaacact aacttaacag ctcaagtgca agcagtatct
    39601 gaatctgcag cagcacctgt ccgtgcaaaa gttcgtccaa catacagtac aaacgcttca
    39661 agttatccaa ttggagaatg tacatgggga gtaaaaacat tggcaccttg ggctggagac
    39721 tactggggta atggagcaca gtgggctaca agtgcagcag cagcaggttt ccgtacaggt
    39781 tcaacacctc aagttggagc aattgcatgt tggaatgatg gtggatatgg tcacgtagcg
    39841 gttgttacag ctgttgaatc aacaacacgt atccaagtat cagaatcaaa ttatgcaggt
    39901 aatcgtacaa ttggaaatca ccgtggatgg ttcaatccaa caacaacttc tgaaggtttt
    39961 gttacatata tttatgcaga ttaatttaca gagggactcg aatagagccc tcttttcagg
    40021 ttttaccgtg acaatcccta ttaaaaatta tatcaaaata gcttgaaaat attggaaaag
    40081 tatggtagaa tgaaaattgt cgtgtgaacg ataatactca ttcttgatga attgtgaagc
    40141 agttgccctt gggtcgtttt gcgagttgaa gtcaagaaga ggaaaaaaac aaaaaggaga
    40201 aatactcatg gcagtaattt caatgaaaca acttcttgag gctggtgtac actttggtca
    40261 ccaaactcgt cgctggaatc ctaagatggc taagtacatc tttactgaac gtaacggaat
    40321 ccacgttatc gacttgcaac aaactgtaaa atacgctgat caagcatacg acttcatgcg
    40381 tgatgcagca gctaacgatg cagttgtatt gttcgttggt actaagaaac aagcagctga
    40441 tgcagttgct gaagaagcag tacgttcagg tcaatacttc atcaaccacc gttggttggg
    40501 tggaactctt acaaactggg gaacaatcca aaaacgtatc gctcgtttga aagaaattaa
    40561 acgtatggaa gaagatggaa ctttcgaagt tcttcctaag aaagaagttg cacttcttaa
    40621 caaacaacgt gcgcgtcttg aaaaattctt gggcggtatc gaagatatgc ctcgtatccc
    40681 agatgtgatg tacgtagttg acccacataa agagcaaatc gctgttaaag aagctaaaaa
    40741 attgggaatc ccagttgtag cgatggttga caccaatact gatccagatg atatcgatgt
    40801 aatcatccca gctaacgatg acgctatccg tgctgttaaa ttgatcacag ctaaattggc
    40861 tgacgctatt atcgaaggac gtcaaggtga ggatgcagta gcagttgaag cagaatttgc
    40921 agcttcagaa actcaagcag attcaattga agaaatcgtt gaagttgtag aaggtgacaa
    40981 cgcttaattt atacaaatag taattaccta ggagggcggg gcttagcccg gctctcctat
    41041 tttcaaaaaa tataggagaa ttaaaatggc agaaattaca gctaaacttg taaaagagtt
    41101 gcgtgaaaaa tctggtgccg gtgttatgga cgctaaaaaa gcgcttgtag aaacagacgg
    41161 tgacatcgaa aaagcgattg aattgcttcg tgaaaaaggt atggctaagg cagctaagaa
    41221 agctgaccgt gttgctgcag aaggtttgac tggtgtttat gttaacggta atgttgcagc
    41281 agttattgaa gtaaacgctg aaactgactt cgttgcaaaa aacgctcaat tcgttgaatt
    41341 ggtaaatact acagctaaag tcattgctga aggaaaacct gctaataatg aagaagctct
    41401 tgctttgata atgccttcag gtgaaactct tgaagctgca tacgtatctg caacagcaac
    41461 tatcggagag aaaatctcat tccgtcgctt tgcattgatt gaaaaaacag acgcacaaca
    41521 ctttggagca taccaacata acggtggacg tatcggtgtt atttcagttg ttgaaggtgg
    41581 agacgaagca cttgctaaac aattgtcaat gcacatcgca gcgatgaaac caacagttct
    41641 ttcttacaaa gaattggatg agcaattcgt taaagatgag ttggcacaat tgaatcacgt
    41701 tatcgaccaa gacaacgaaa gccgtgcaat ggttaataaa ccagctcttc cacacttgaa
    41761 gtatggatca aaagctcaat taactgatga tgttattgct caagctgaag ctgacatcaa
    41821 agctgaattg gctgcagaag gcaaaccaga aaaaatctgg gacaaaatta tcccaggtaa
    41881 aatggatcgc ttcatgcttg ataatactaa agttgaccaa gcttacacac ttcttgcaca
    41941 agtttacatc atggatgaca gcaagacagt tgaagcatac cttgaatcag ttaacgcttc
    42001 ggtagttgag tttgctcgct ttgaagttgg tgaaggtatc gagaaagctg caaacgactt
    42061 cgaagctgaa gttgcagcta caatggcagc agccttgaat aactaataat agaaaggaag
    42121 caatttgctt ccttttttgt atgcagtcga tccttatagg gagagcttcc tattttcaag
    42181 gtaaaaataa aaagccctat aataagggcc aattgtattt aggagactaa acttcaaatt
    42241 catagagtgc tgtagagaga taacgttcac cgttatctgg tgctagagca aggacttttt
    42301 tacctgtacc taattttttg gcaacctcga tggctccgta gatagctgca gctgaggaaa
    42361 tccctacaag gaagccttct tttccaccaa tttcacgtcc gagtgcaaga gcgtcatctg
    42421 atgttacacg aacgatacca tcataggctt tagtatcaag tgtatcagga ataaatccag
    42481 ctgagatacc ttgaattttg tgaggaccgg gtttttcacc agatagaata gcagattcat
    42541 ctgcttctac tgcaaaaact tgaatgttag aattttctga tttgagtgca tgagaaacac
    42601 cagaaatcgt tccaccggta cctactccag caacaaaggc atctaatcca tctttaccga
    42661 aagcagctag tatctcagct cctgttgttc tttcgtgtac ttctggatta gctggattgt
    42721 caaattgaag aggaaggaaa ccatcacgtt cagcagcgat ttcttgagcc ttagcaatag
    42781 cacctttcat tccctcgcta ccaggagtta ggacgagttc agcaccataa gcttggataa
    42841 ttttacgtcg ttctacactc atagtttcag gcataacgat gacgacttta taccctttag
    42901 cagcacctac ccatgaaagt ccaataccag tgtttccact tgttgcttca acaatagtag
    42961 aaccaggttt cagaatacca tcttgttcag ctttttcaat catgctaagg gcaatacggt
    43021 cttttacaga tgaaccagga ttaaatgctt caagctttat atagacgtct gcagcacctt
    43081 ctggcacgat gttgttaagt ttaacaattg gtgtttgacc gattaattca gtaatgttgt
    43141 tataaataga catatgaata cctctttgta taagatatct ttagtataac gctatctata
    43201 ccatttgtaa aatatagaaa tcctatcgaa gcgataggat ttctatatat catagatcaa
    43261 agtcattaat tttcaagtga ttgcgttcag ctaattctag taaataggtg tgaaggaaaa
    43321 cgatatcagg tttcgtttga attgcttcat tttctagtat attttggtac gcatcttttt
    43381 attttgctcg ctaaagtagt tgtgagaatg tcaacgaaac gctgtattat tcattgttta
    43441 cactaagttt acaggaactt caacctctcg taaaccttgg tcagttaaag tgacttttcc
    43501 attaaaaaac tccacaagtg cagctttaat agtttctttt tcttctttat caacataaat
    43561 catcgtatcg acttgatctg taaagtttgt atccagctcc atgagatcat gttctttaag
    43621 gaagttactg tactcttggt actgagcata agacatttga atagcaatgc cagcctgttc
    43681 ttttatttca ataataccaa tttctttgac agctaaggcg acactgccgg cgtaagcacg
    43741 aattagtcct ccagcaccta gtttaatacc accaaagtag cgtgtcacga ccacacagac
    43801 attggtgaga ttgtgatttt ctagtacccc aagcatggga acaccagcag taccactagg
    43861 ctcaccatca tcacttgtac gtttaatttc actacgttct ccaataataa aggcagagca
    43921 gttatgtgtc gctttgtagt gttctttttt gatggcagta atgaagtcac gagcctcttc
    43981 ttcgctataa acacgcttgg catggcagat aaagcgagat tttttgattt cttcttggac
    44041 ttggccgtcc tctttaattg tcctaaattc catgatttaa ttgtactaaa aaatcatcta
    44101 aagtgctagt ttttacgaat aaagaagtat gaaagtaaat ttagattatc tcggtcgttt
    44161 atttactgag aatgaattaa cagaagaaga acgtcagttg gcggagaaac ttccagcaat
    44221 gagaaaggag aaggggaaac ttttatgtca acgttgtaat agtactattc tagaagaatg
    44281 gtatttgccc atcggtgctt actattgtcg agagtgcttg ctgatgaagc gagtcagaag
    44341 tgatcaaact ttatactatt ttccgcagga ggattttccg aagcaagatg ttctcaaatg
    44401 gcgcggccaa ttaactcctt ttcaagagaa ggtgtcagag ggactgcttc aagcagtaga
    44461 caagcaaaag ccaaccttag ttcatgcggt aacaggagct ggaaagacag aaatgattta
    44521 tcaagtagtg gctaaagtga tcaatgcggg tggtgcagtg tgtttggcta gtcctcgcat
    44581 agatgtttgt ttggagctgt acaagcgcct gcaacaggat ttttcttgcg ggatagcttt
    44641 gctacatgga gaatcggaac cttattttcg aacaccacta gttgttgcaa caacccatca
    44701 gttattgaag ttttatcaag cttttgattt gctgatagtg gatgaagtag atgcttttcc
    44761 ttatgttgat aatcccacgc tttaccatgc tgtcaagaat agtgtaaagg agaatggatt
    44821 gagaatcttt ttaacagcga cttcgaccaa tgagttagat aaaaaggtcc gtttaggaga
    44881 actaaaaaga ctgaatttac cgagacggtt tcatggaaat ccgttgatta ttccaaaacc
    44941 aatttggtta tcggatttta atcgctactt agacaagaat cgtttgtcac caaagttaaa
    45001 gtcctatatt gagaagcaga gaaagacagc ttatccgtta ctcatttttg cttcagaaat
    45061 taagaaaggg gagcagttag aagaaatctt acaggagcaa tttccaaatg agaaaattgg
    45121 ctttgtatct tctgtaacag aggatcgatt agagcaagta caagcttttc gagatggaga
    45181 actgacaata cttatcagta cgacaatctt ggagcgtgga gttaccttcc cttgtgtgga
    45241 tgttttcgta gtagaggcca atcatcgttt gtttaccaag tctagtttga ttcagattgg
    45301 tggacgagtt ggacgaagca tggatagacc gacaggagat ttgcttttct tccatgatgg
    45361 gttaaatgct tcaatcaaga aggcgattaa ggaaattcag atgatgaata aggaggctgg
    45421 tctatgaagt gcttgttatg tgggcagact atgaagactg ttttaacttt tagtagtctc
    45481 ttacttctga ggaatgatga ctcttgtctt tgttcagact gtgattctac ttttgaaaga
    45541 attggggaag agaactgtcc aaattgtatg aaaacagagt tgtcaacaaa gtgtcaagat
    45601 tgtcaacttt ggtgtaaaga aggagttgaa gtcagtcata gagcgatttt tacttacaat
    45661 caagctatga aggatttttt cagtcggtat aagtttgatg gagacttcct gttaagaaaa
    45721 gttttcgctt catttttaag tgaggagttg aaaaagtaca aagagtatca atttgttgta
    45781 attcccctaa gtcctgatag atatgctaac agaggattta atcaggttga gggcttggta
    45841 gaggcagcag gctttgagta tctggattta ttagagaaaa gagaagagag agccagttct
    45901 tctaaaaatc gttcagagcg cttggggaca gaacttcctt tctatattaa aagtggagtc
    45961 actattccta aaaaaatcct acttatagat gatatctata ctacaggagc aactataaat
    46021 cgtgttaaga aactgttgga agaagccggt gctaaggatg taaaaacatt ttcccttgta
    46081 agatgaggaa aaaatttgca aaaatagaat gaaagcgtta taataaaatc ataaaaacaa
    46141 aaatgtttag aaagaaggta ctcatatgat taaatatagt atccgtggtg aaaacctaga
    46201 agtaacagaa gcaattcgtg attatgtagt ttctaaactc gaaaagatcg aaaagtactt
    46261 ccaaccagaa caagagttgg atgcccgaat taacttaaaa gtttatcgtg aaaaaacggc
    46321 taaagtggaa gtaacgattc cgcttggatc tattactctc cgcgcagaag atgtatctca
    46381 agatatgtat ggttcaattg accttgtaac tgataaaatt gaacgtcaga ttcgtaaaaa
    46441 taaaacaaaa atcgagcgta aaaataaaaa taaggtagca actggtcaat tatttacaga
    46501 tgctttggtg gaagattcaa atattgtcca gtctaaagtt gttcgttcaa aacaaattga
    46561 tttaaaacca atggatttgg aagaagcaat tctacaaatg gatttattgg ggcatgattt
    46621 ctttatctat gtggatgttg aagatcagac aaccaatgtg atttatcgtc gtgaggatgg
    46681 cgaaattggt ttgttagagg ttaaagaatc ttaatttcaa tatgtgtaaa ggtaggttta
    46741 ctgaattgta aactaccttt ttcttataat tgatagaatt actgattaca cttttaaaaa
    46801 gtcgcttttt gaggggtatt atggtataat gggtgccaag aggttttgaa tgaaaaaatt
    46861 ttatgtaagt ccaatttttc ctattctagt aggattgatt gcgtttggag tcttatccac
    46921 tttcattatt tttgttaata ataatctgtt gacggtttta attttgtttc tttttgtagg
    46981 aggctatgtt tttttattta agaaactgag agtgcattat acaaggagtg atgtagaaca
    47041 gatacagtat gtaaaccacc aagcggaaga aagtttgaca gctctattgg aacagatgcc
    47101 tgtaggtgtt atgaaattga atttatcttc tggagaggtt gagtggttta atccctatgc
    47161 tgaattgatt ttgaccaagg aagatggtga ttttgattta gaagctgttc aaacgattat
    47221 caaggcttca gtaggaaatc cgtctactta tgccaagctt ggtgagaagc gttatgctgt
    47281 tcatatggat gcttcttccg gtgttttgta ttttgtagat gtatccaggg aacaagccat
    47341 aacagatgaa ttggtaacaa gtcgaccagt gattgggatt gtctctgtgg ataattatga
    47401 tgatttggag gatgcaactt ctgagtcaga tattagtcaa atcaatagtt ttgtagctaa
    47461 ttttatatca gagttttcag aaaaatacat gatgttttct cgtcgggtaa gtatggatcg
    47521 attttatcta tttactgact acacggtgct tgagggcttg atgaatgata aattttctgt
    47581 tattgatgct ttcagagaag agtcgaaaca gagacagttg cccttgacct taagtatggg
    47641 attttcttat ggcgatggaa atcatgatga gatagggaaa gttgctttgc tcaatttgaa
    47701 cttggctgaa gtacgtggtg gcgaccaggt ggttgttaag gaaaacgacg aaacgaaaaa
    47761 tccagtttat tttggtggtg ggtctgctgc ttcaatcaag cgtacacgga ctcgtacgcg
    47821 cgctatgatg acagctattt cagataagat tcggagtgta gatcaggttt ttgtagtcgg
    47881 tcacaaaaat ttagacatgg atgctttggg ctctgctgta ggtatgcagt tgttcgccag
    47941 caatgtgatt gaaaatagct atgctcttta tgatgaagaa caaatgtctc cagatattga
    48001 acgagctgtt tcattcatag aaaaagaagg agttacgaag ttgttgtctg ttaaggatgc
    48061 aatggggatg gtgaccaatc gttctttgtt gattcttgta gaccattcaa agacagcctt
    48121 aacattatca aaagaatttt atgatttatt tactcaaacc attgttattg accaccatag
    48181 aagggatcag gattttccag ataatgcggt cattacttat atcgaaagtg gtgcaagtag
    48241 tgccagtgag ttggtaacgg aattgattca gttccagaat tctaagaaaa atcgtttgag
    48301 tcgtatgcaa gcaagtgttt tgatggctgg tatgatgttg gatactaaaa atttcacctc
    48361 gcgagtaact agtcggacat ttgatgttgc tagctatctc agaacgcgcg gaagtgatag
    48421 tattgctatc caggaaatcg ctgcgacaga ttttgaagaa tatcgtgagg tcaatgaact
    48481 tattttacag gggtgtaaat taggttcaga tgtactaata gcagaggcta aggacacgaa
    48541 atgctatgat acagttgtta ttagtaaggc agcagatgcc atgttagcca tgtcaggtat
    48601 tgaagcgagt tttgttcttg cgaagaatac acaaggattt atctctatct cagctcgaag
    48661 tcgtagtaaa ctgaatgtac aacggattat ggaagagtta ggcggtggag gccactttaa
    48721 tttggcagca gctcaaatta aagatgtaac cttgtcagaa gcaggtgaaa aactgacaga
    48781 aattgtatta aatgaaataa aggaaaagga gaaagaagaa tgaaagtaat ctttttagca
    48841 gatgttaaag gaaaaggtaa aaaaggcgaa attaaggaag taccaacagg gtatgcgcaa
    48901 aactttctta tcaaaaagaa tctagccaaa gaagcgactg ctcaagctgt aggtgaactt
    48961 cgtggtaaac aaaaatcgga agaaaaagct cacgctgaga tgattgcaga aggaaaagca
    49021 attaaagcac aacttgaagc agaagaaact gttgtagaat ttgttgaaaa agttggtcca
    49081 gatggtcgta cctttggttc tattaccaat aagaagattg cagaagaatt gcaaaagcaa
    49141 tttggaatta agattgataa acgtcatatt caagtacaag ctccgattcg agcggttggt
    49201 ttgattgatg tgccagtgaa aatctatcaa gatatcacaa gtgtaatcaa tcttcgtgtg
    49261 aaagaaggat aagtttacac cttcttgaca agattgtaaa aggaagggaa gtctgatggc
    49321 ggaagtagaa gagttacgag tacaacctca agatatctta gctgagcaat ccgttttagg
    49381 ggctatcttt attgatgaga gtaaacttgt ttttgtgcga gaatacattg agtctcggga
    49441 cttttttaag tatgcccatc gtttgatttt ccaagccatg gtcgatttat ccgatcgtgg
    49501 tgatgccata gatgcaacaa cggttcgtac tatccttgat aatcaaggtg atttgcagaa
    49561 tattggtggc ttgtcttact tggttgagat tgtcaattct gtgccaactt ctgctaatgc
    49621 ggagtattat gctaagattg ttgcagaaaa agcaatgcta cgtcgtttaa ttgccaagtt
    49681 gacagaatct gtcaaccaag cttacgaagc gtcacaacca gctgatgaaa ttattgctca
    49741 ggcagaaaaa gggctgattg atgtcagtga aaatgcaaat cgaagcgggt ttaagaacat
    49801 tcgagatgtg ttgaatctca actttggaaa tctggaagct cgctcgcaac aaacgaccga
    49861 tattacaggt attgcgacag gttatcgtga tttggatcat atgacaacag gacttcatga
    49921 ggaggagttg attatcttag cagctcgtcc agcagttggt aagacagcat ttgccttgaa
    49981 tatcgctcag aacattggga ctaagttgga caaaacggtt gctatttttt cactcgaaat
    50041 gggtgcggaa agcttggtag accgtatgtt agctgcagaa ggcttggtgg agtcacattc
    50101 tatccgtaca gggcaattga cagatgagga gtggcaaaaa tatactattg ctcagggtaa
    50161 tctagctaac gccagtatct atatcgatga tacgccaggt attcggatta cagagattcg
    50221 ttctcgttct cgtaaattgg ctcaagaaac tggaaatctt ggtttgattt tgatagacta
    50281 tttgcaactt atcacgggaa ctggtcgaga aaatcgtcaa caagaagttt ctgaaatttc
    50341 tcgtcagttg aaaatactag ccaaggaatt gaaggttcca gtaatcgctc tgagtcagct
    50401 ttctcgtggt gtagaacaac gtcaggacaa gagaccggtc ttgtctgata ttcgtgaatc
    50461 tgggtctatt gagcaggacg ctgatatcgt agcttttctc tatcgcgatg actactatga
    50521 acgtggtggt gaagaagagg agggtatccc aaataataag gtggaagtta ttatcgagaa
    50581 aaaccgtagt ggagctcgtg gaacagtgga attgattttc caaaaagaat acaataaatt
    50641 ttcaagtatc tcaaagaggg aggcataaga tgtcagatgc atttacagat gtagccaaga
    50701 tgaaaaaaat caaagaagaa atcaaggcac atgagggaca agtcgtagaa atgactttgg
    50761 agaatggtcg taagcgccaa aaaaatagat tgggtaagct aattgaagtt tatccatctc
    50821 tatttattgt ggagtttggg gatgtggaag gagataaaca agttaatgtt tacgttgaat
    50881 cctttactta ctcagatatt cttacagaaa agaatttgat tcattatctt gactaaagtg
    50941 agaaattttc tcactttttc ttttttctcc gaataattta ggtgaaggca atcatcgctt
    51001 tatattattt ttcaaggagg aagaatgaaa attttaccgt ttatagcaag aggaacaagt
    51061 tattacttga agatgtcagt taaaaagctt gttccttttt tagtagtagg attgatgcta
    51121 gcagctggtg atagtgtcta tgcctattcc ggaggaaatg gatcgattgc gcgtggggat
    51181 gattatcctg cttattataa aaatgggagc caggagattg atcagtggcg catgtattct
    51241 cgtcagtgta cttcttttgt agcctttcgt ttgagtaatg tcaatggttt tgaaattccg
    51301 gcagcttatg gaaatgcgaa tgaatgggga catcgtgctc gtcgggaagg ttatcgtgta
    51361 gataatacac cgacgattgg ttccattact tggtctactg caggaactta tggtcatgtt
    51421 gcctgggtat caaatgtaat gggagatcag attgagattg aggaatataa ctatggttat
    51481 acagaatcct ataataaacg agttataaaa gcaaacacga tgacaggatt tattcatttt
    51541 aaagatttga atggtggcag tgttgggaat agtcaatcct caacttcaac aggcggaact
    51601 cattatttta agacaaagtc tgctattaaa actgaacctc tagttagcgg aactgtgatt
    51661 gattactatt atcctgggga gaaggttcat tatgatcaga tacttgaaaa agacggctat
    51721 aagtggttga gttatactgc ctataatgga agctatcgtt atgttcaatt ggaggctgtg
    51781 aataaaaatc ctctaggtca ttctgttctt tcttcaacag gtggaactca ttattttaag
    51841 accaagtctg ctatcaaaac tgaaccccta gttagcggaa ctgtgattga ttactattat
    51901 cctggggaga aggttcatta tgatcagata cttgaaaaag acggctacaa gtggttgagt
    51961 tatactgcct ataatggaag tcgtcgctat atacagctag agggagtgac ttcttcacaa
    52021 aattatcaga atcaatcagg aaatatctct agctatggat ccaataatag ttcaactgtc
    52081 ggttggaaga aaataaatgg tagttggtat catttcaaat caaatggttc taaatcaaca
    52141 ggatggctga aagacggttc tagctggtat tatttgaaat tatctggtga aatgcagaca
    52201 ggatggttaa aggagaatgg ctcgtggtat tatctgggta gttcaggggc aatgaaaaca
    52261 ggctggtacc aggtctctgg taagtggtat tattcttact cttcaggcgc cttagctgtt
    52321 aatacgacgg tggatggcta cagagtaaac agtgatggag aacgagtata gaaaattgga
    52381 gtaggagaaa tttcctgctc ttttctgtaa gcagtttcct tgacattttt cttattttgc
    52441 gctatcatat atacatataa tatatgggag tctgtgtaca gtctgagagg aagtgttaaa
    52501 cttcgaccgc acctgatctg ggtaatgcca gcggagggaa cgatacttag tctaattttg
    52561 caccttttcc atgtatggta aaggtttttc ttttttttaa aaggaaaacg agaagaggag
    52621 gttcttatga aagcaagcat tgccttgcaa gttttacccc tagcacaggg gattgatcgg
    52681 atagctgtta ttgatcaggt cattgcttat ctgcaaactc aagaagtgac gatggtagtg
    52741 acaccatttg aaacggtctt ggaaggggag tttgatgagc ttatgcgcat tctaaaagaa
    52801 gcgctggaag tggcagggca ggaggcagac aatgtctttg ccaatgtcaa aataaatgta
    52861 ggagagattt taagtattga tgagaaactt gagaagtata ctgagacgac acattagtct
    52921 attgggcttt ctcggagtat tgtcaatctg gcagttagca ggttttctta aacttctccc
    52981 caagtttatc ctgccgacac ctcttgaaat tctccagccc tttgttcgtg acagagaatt
    53041 tctctggcac catagctggg cgaccttgag agtggcttta ctggggctga ttttgggagt
    53101 tttgattgcc tgtcttatgg ctgtgctcat ggatagtttg acttggctca atgacctgat
    53161 ttaccctatg atggtggtca ttcagaccat tccgaccatt gccatagctc ctatcctggt
    53221 cttgtggctg ggttatggga ttttgcccaa gattgtcttg attatcttaa cgacaacctt
    53281 tcccatcatc gtcagcattt tggacggttt taggcattgc gacaaggata tgctgacctt
    53341 gtttagtctg atgcgggcca agccttggca aatcctgtgg cattttaaaa ttccagtcag
    53401 cctgccctac ttttatgctg gtctgagggt cagtgtctcc tacgctttta tcacaacagt
    53461 ggtatctgag tggttgggag gctttgaggg gcttggtgtt tatatgattc agtccaagaa
    53521 attgtttcag tatgatacca tgttcgctat tattattctg gtatcgatta tcagcctttt
    53581 gggtatgaag ttggtcgata ttagtgaaaa atatgttatt aaatggaaac gttcgtagaa
    53641 ttagaatgtt tctgaaaaag aaaagaggaa atcaaaatga agaaaacatg gaaagtgttt
    53701 ttaacgcttg taacagctct tgtagctgtt gtgcttgtgg cctgtggtca aggaactgct
    53761 tctaaagaca acaaagaggc agaacttaag aaggttgact ttatcctaga ctggacacca
    53821 aataccaacc acacagggct ttatgttgcc aaggaaaaag gttatttcaa agaagctgga
    53881 gtggatgttg atttgaaatt gccaccagaa gaaagttctt ctgacttggt tatcaacgga
    53941 aaggcaccat ttgcagtgta tttccaagac tacatggcta agaaattgga aaaaggagca
    54001 ggaatcactg ccgttgcagc tattgttgaa cacaatacat caggaatcat ctctcgtaaa
    54061 tctgataatg taagcagtcc aaaagacttg gttggtaaga aatatgggac atggaatgac
    54121 ccaactgaac ttgctatgtt gaaaaccttg gtagaatctc aaggtggaga ctttgagaag
    54181 gttgaaaaag taccaaataa cgactcaaac tcaatcacac cgattgccaa tggcgtcttt
    54241 gatactgctt ggatttacta cggttgggat ggtatccttg ctaaatctca aggtgtagat
    54301 gctaacttca tgtacttgaa agactatgtc aaggagtttg actactattc accagttatc
    54361 atcgcaaaca acgactatct gaaagataac aaagaagaag ctcgcaaagt catccaagcc
    54421 atcaaaaaag gctaccaata tgccatggaa catccagaag aagctgcaga tattctcatc
    54481 aagaatgcac ctgaactcaa ggaaaaacgt gactttgtca tcgaatctca aaaatacttg
    54541 tcaaaagaat acgcaagcga caaggaaaaa tggggtcaat ttgacgcagc tcgctggaat
    54601 gctttctata aatgggataa agaaaatggt atccttaaag aagacttgac agacaaaggc
    54661 ttcaccaacg aatttgtgaa ataatgacag aaattagact agagcacgtc agttatgcct
    54721 atggtcagga gaggatttta gaggatatca acctacaggt gacttcaggc gaagtggttt
    54781 ccatcctagg cccaagtggt gttggaaaga ccaccctctt taatctaatc gctgggattt
    54841 tagaagttca gtcagggaga attgtccttg atggtgaaga aaatcccaag gggcgcgtga
    54901 gttatatgtt gcaaaaggat ctgctcttgg agcacaagac ggtgcttgga aatatcattc
    54961 tgcccctctt gattcaaaag gtggataagg cagaagctat ttcccgcgcg gataaaattc
    55021 ttgcgacctt ccagctgaca gctgtaagag acaagtatcc tcatgaactt agcggtggga
    55081 tgcgccagcg tgtagcctta ctccggacct acctttttgg gcacaagctc tttctcttag
    55141 atgaggcctt tagcgccttg gatgagatga caaagatgga actccacgct tggtatcttg
    55201 agattcacaa gcagttgcag ctaacaacct tgatcatcac gcatagtatt gaggaggccc
    55261 tcaatctcag cgaccgcatc tatatcttga aaaatcgccc tgggcagatt gtttcagaaa
    55321 ttaaactaga ttggtctgaa gatgaggaca aggaagtcca aaagattgcc tacaaacgtc
    55381 aaatcttggc agaattaggc ttagataagt agaaaaatag ggagttggtg aagattatcc
    55441 tttaccagcg ccctttttct tttaaaaatg agaaaatttc ggtataatag tcaaacaagg
    55501 tcaaggtcta aagagagagg tgggtttgtt atgagattta aaaatacatc ggatcatatt
    55561 gaggcctaca tcaaggcgat tttagatcaa tctggtatcg tggagttgca acggagtcag
    55621 ttggcagata cctttcaggt tgttcctagt cagattaact acgtgatcaa gacacgcttt
    55681 acggaaagta gaggctactt ggttgaaagt aagcgtggtg gcggaggcta cattcgtata
    55741 ggacggattg agttttctag tcatcatgaa atgctccggg agctgcttta ctcgattggt
    55801 gagcgagtca gtcaagaaat ttatgaggat attctccagc ttttggttga gcaggaattg
    55861 atgaccaagc aggagatgaa tttgctagaa tcagtagctt tggagcgcgt tttaggagaa
    55921 gaagctccag ttgttcgagc aaacatgcta cgtcagatca tacaagaggt agatagaaaa
    55981 gggaagtaag atgaactatt caaaagcatt gaatgaatgt atcgaaagtg cctacatggt
    56041 tgctggacat tttggagctc gttatctaga gtcttggcac ttgttgattg ccatgtctaa
    56101 tcacagttat agtgtagcag gggcaacttt aaatgattat ccgtatgaga tggaccgttt
    56161 agaagaagtg gctttggaac tgactgaaac ggactatagc caggatgaaa cctttacgga
    56221 attgccgttc tcccgtcgtt tgcaggttct ttttgatgaa gcagagtatg tagcgtcagt
    56281 ggtccatgct aaggtactag ggacagagca cgtcctctat gcgattttgc atgatggcaa
    56341 tgccttggcg actcgtatct tggagagggc tggtttttct tatgaagaca agaaagatca
    56401 ggtcaagatt gctgctcttc gtcgaaattt agaagaacgg gcaggctgga ctcgtgaaga
    56461 tctcaaggct ttacgccaac gccatcgtac agtagctgac aagcaaaatt ctatggccaa
    56521 tatgatgggc atgccgcaga ctccgagtgg tggtctcgag gattatacgc atgatttgac
    56581 agagcaagcg cgttctggca agttagaacc agtcatcggt cgggacaagg aaatctcacg
    56641 tatgattcaa atcttgagcc gtaagactaa gaacaaccct gtcttggttg gggatgctgg
    56701 tgtcgggaaa acagctctgg cccttggtct tgcccagcgt attgctagtg gtgacgtgcc
    56761 tgcggaaatg gctaagatgc gcgtgttaga acttgatttg atgaatgtcg ttgcagggac
    56821 acgcttccgt ggtgactttg aagaacgcat gaataatatc atcaaggata ttgaagaaga
    56881 tggccaagtc atcctcttta tcgatgaact ccacaccatc atgggttctg gtagcgggat
    56941 tgattcgact ctggatgcgg ccaatatctt gaaaccagcc ttggcgcgtg gaactttgag
    57001 aacggttggt gccactactc aggaagaata tcaaaaacat atcgaaaaag atgcggcact
    57061 ttctcgtcgt ttcgctaaag tgacgattga agaaccaagt gtggcagata gtatgactat
    57121 tttacaaggt ttgaaggcga cttatgagaa acatcaccgt gtacaaatca cagatgaagc
    57181 ggttgaaaca gcggttaaga tggctcatcg ttatttaacc agtcgtcact tgccagactc
    57241 tgctatcgat ctcttggatg aggcggcagc aacagtgcaa aataaatcaa agcatgtaaa
    57301 agcagacgat tctgacttga gtccagctga caaggccctg atggatggca agtggaaaca
    57361 ggcagcccag ctaatcgcaa aagaagagga agtacctgtc tacaaagact tggtgacaga
    57421 gtctgatatt ttgaccacct tgagtcgctt gtcaggaatc ccagttcaaa aactgactca
    57481 gactgacgct aagaaatatc taaatcttga agcagaactc cataaacggg ttatcggtca
    57541 agatcaagct gtttcaagta ttagtcgtgc gattcgccgt aatcagtcag gaattcgcag
    57601 tcacaagcgt ccgatcggtt cctttatgtt cctaggaccc acaggtgtcg gtaagaccga
    57661 gttggccaag gctttggcag aagctctctt tgatgacgaa tcagccctta tccgctttga
    57721 tatgagtgag tatatggaga aattcgcagc cagccgtcta aatggagctc ctccaggcta
    57781 tgtgggttac gaagaaggtg gggagttgac agagaaggtt cgcaataaac cctattccgt
    57841 tctcctcttt gatgaggtag agaaggctca cccagatatc tttaatgttc tcttgcaggt
    57901 tctggatgac ggtgtcttga cagatagcaa gggacgcaag gtcgattttt caaataccat
    57961 tatcattatg acatcgaacc taggtgcgac tgcccttcgt gatgataaga ctgttggttt
    58021 tggggctaag gatattcgtt ttgaccagga aaatatggaa aaacgcatgt ttgaagaact
    58081 gaaaaaagct tatagaccgg aattcatcaa ccgtattgat gagaaggtgg tcttccatag
    58141 cctatctagt gaccatatgc aggaagtggt gaagattatg gtcaagcctt tagtggcaag
    58201 tttggctgaa aaaggcattg acttgaaatt acaagcttca gctctgaaat tgttagcaaa
    58261 tcaagtatat gacccagaga tgggagctcg cccacttcgc agaaccctgc aaacagaagt
    58321 ggaggacaag ttggcagaac ttcttctcaa gggagattta gtggcaggca gcacacttaa
    58381 gattggtgtc aaagcaggcc agttaaaatt tgatattgca taaaagaata aaagtatcag
    58441 catctgacca taagtcacag tggagtgaaa ctcaatgaaa atcaaagagc aaactaggca
    58501 gctagccgca ggttgctcaa aacactgttt tgaggttgca gatagagctg acgtggtttg
    58561 aagagatttt tgaagagtat aagctgcaag atgaatgatt ttcttgtatt gacgttgttg
    58621 ttgacaaaaa gtagcggata aatgaaatcc attccattat catagatgat aggctggtag
    58681 gaaattttca aatagcatac aggaaataga tgtatggagt tctggtagta gaaagggaga
    58741 gagatgaaca ttttagttgc agatgacgag gaaatgatta gagaaggaat tgcagcattt
    58801 ctgacagaag agggttatca tgtcattatg gctaaggatg gacaagaggt cttggaaaaa
    58861 tttcaagatc tccctatcca tctcatggta ctggatttaa tgatgcctag gaagagtggt
    58921 tttgaagtgt taaaagaaat caatcaaaag cacgatattc ctgtcatcgt cttgagtgct
    58981 ctgggagatg aaactactca gtcacaggta tttgatctct atgctgatga tcatgtgaca
    59041 aaaccttttt ctttggtact gcttgtcaag cgtattaagg cgcttatcag acgttactac
    59101 gtcatagagg atctttggcg atatcaggat gtaacagtgg attttacctc ttacaaagca
    59161 cattataaaa atgaagaaat tgatctcaaa ccaaaggaat tactggtact aaagtgtttg
    59221 attcagcata aaaatcaagt tttaagtaga gagcagatat tggaagaaat ttcaaaagat
    59281 gtagctgatt taccttgtga tagggtcgtt gatgtctata ttcgtactct tcgcaaaaaa
    59341 ttagctttag attgtatcgt gactgtgaaa aatgttgggt ataagattag cttatgataa
    59401 aaaatcctaa attattaacc aagtcttttt taagaagttt tgcaattcta ggtggtgttg
    59461 gtctagtcat tcatatagct atttatttga cctttccttt ttattatatt caactggagg
    59521 gggaaaagtt taatgagagc gcaagagtgt ttacggagta tttaaagact aagacatctg
    59581 atgaaattcc aagcttactc cagtcttatt caaagtcctt gaccatatct gctcacctta
    59641 aaagagatat tgtagataag cggctccctc ttgtgcatga cttggatatt aaagatggaa
    59701 agctatcaaa ttatatcgtg atgttagata tgtctgttag tacagcagat ggtaaacagg
    59761 taacagtgca atttgttcac ggggtggatg tctacaaaga agcaaagaat attttgcttt
    59821 tgtatctccc atatacattt ttggttacaa ttgctttttc ctttgttttt tcttattttt
    59881 atactaaacg cttgctcaat cctctttttt acatttcaga agtgactagt aaaatgcaag
    59941 atttggatga caatattcgt tttgatgaaa gtaggaaaga tgaagttggt gaagttggaa
    60001 aacagattaa tggtatgtat gagcacttgt tgaaggttat tcatgagttg gaaagtcgta
    60061 atgagcaaat tgtaaaattg caaaatcaaa aggtttcctt tgtccgcgga gcatcacatg
    60121 agttgaaaac ccctttagcc agtcttagaa ttatcctaga gaatatgcag cataatattg
    60181 gagattacaa agatcatcca aaatatattg caaagagtat aaataagatt gaccagatga
    60241 gccacttatt ggaagaagta ctggagtctt ctaaattcca agagtggaca gagtgtcgtg
    60301 agaccttgac tgttaagcca gttttagtag atattttatc acgttatcaa gaattagctc
    60361 attcaatagg tgttacaatt gaaaatcaat tgacagatgc taccagggtc gtcatgagtc
    60421 ttagggcatt ggataaggtt ttgacaaacc tgattagtaa tgcaattaaa tattcagata
    60481 aaaatgggcg cgtaatcata tctgagcaag atggctatct ctctatcaaa aatacatgtg
    60541 cgcctctaag tgaccaagaa ctagaacatt tatttgatat attctatcat tctcaaatcg
    60601 tgacagataa ggatgaaagt tccggtttgg gtctttacat tgtgaataat attttagaaa
    60661 gctatcaaat ggattatagt tttctccctt atgaacacgg tatggaattt aagattagct
    60721 tgtagacaga ttagtttttt attaaagttc atatagggtt aacataagtg tgttattctt
    60781 tgtgtagata aaagaaagga tactaatatg gtattagcga ttattttagt aacattcttt
    60841 attcgattga tttttttaaa gcgttcgata gagaatgaga aacgaatcct tagcaatggc
    60901 gggaaagaat ttggagttga gaatacaaaa cgattaacta tggctcatat tgttttttat
    60961 ctctcttgct tggttgaggc aatggtgcac aagacaattt ttgatgtcat gggcatggtt
    61021 ggtttagtct tgcttatttt ttctatgctg atgttgatgt tggtgattca cttgttggga
    61081 gatatttgga cagtgaagct tatgcttgtc aataatcaca aatatgtaga tcatatcttg
    61141 tttaggacag taaaacatcc taattacttt ttaaatattc ttcctgagtt gattggcttg
    61201 accttgttga gtcatgctta tgtgactttt gttttagttt ttccagttta tgcagttatt
    61261 ttgtatcgac gaatagctga agaggaaaag ctattacatg aagttataat cccaaatgga
    61321 agcataaaga gataaataca aaattcgatt tatatacagt tcatattgaa gtgatatagt
    61381 aaggttaaag aaaaaatata gaaggaaata aacatgtttg catcaaaaag cgaaagaaaa
    61441 gtacattatt caattcgtaa atttagtatt ggagtagcta gtgtagctgt tgccagtctt
    61501 tttatgggaa gtgtggttca tgcgacagag aacgagggaa ttgcccaagt agtcacttct
    61561 tctaatatgg caaatacaga acataggaaa gctgctaaac aagtcgatga atatatagaa
    61621 aaaatgatcc aattagatag aagaaaacat acccaaaatg tcggcttatt cacaaagttg
    61681 ggcgcaatta aaacggagta tttgcgtgga ttaagtgttt caaaagagaa gtcgacagct
    61741 gagttgccgt cagaaataaa agcaaagtta accgcagctt ttgagcagtt taaaaaagat
    61801 acattaccaa cagaaccagg aaaaaaggta gcagaagcta agaagaaggt tgaagaagct
    61861 gagaagaagg tagcagaagc taagaaaaaa gccaaggctc aaaaagaaga agatcaccgt
    61921 aactacccaa ccattactta caaaacgctt gaccttgaaa ttgctgagtt cgatgtgaaa
    61981 gttaaagaag cggagcttga actagtaaaa aaggaagctg acgaatctcg aaacgagggc
    62041 acaattaacc aagcaaaagc gaaagttgag agtgaaaaag ctgaggctac aaggttaaaa
    62101 aaaatcaaga cagatcgtga aaaagcagaa gaagaagcta aacgaagagc agatgctaaa
    62161 gagcaagatg aatcaaagag gcgaaagagt cggggaaaac gaggagctct tggagagcaa
    62221 gcaacacctg ataaaaaaga aaatgatgcg aagtcttcag attctagcgt aggtgaagaa
    62281 actcttccaa gcccatccct gaaaccagga aaaaaggtag cagaagctga gaagaaggtt
    62341 gaagaagctg ataaaaaagc caaggctcaa aaagaagaag atcgccgtaa ctacccaacc
    62401 aatacttaca aaacgcttga acttgaaatt gctgagtccg atgtgaaagt taaagaagcg
    62461 gagcttgaac tagtaaaaga ggaagctaag gaatctcgaa acgaggaaaa aattaagcaa
    62521 gcaaaagcga aagttgagag taaaaaagct gaggctacaa ggttagaaaa aatcaagaca
    62581 gatcgtaaaa aagcagaaga agaagctaaa cgaaaagcag cagaagaaga taaagttaaa
    62641 gaaaaaccag ctgaacaacc acaaccagcg ccggctcctc aaccagaaaa accagctgaa
    62701 gagcctgaga atccagttcc agctccaaaa ccagagaatc cagctgaaca accaaaagca
    62761 gaaaaaccag ctgatcaaca agctgaagaa gactatgctc gtagatcaga agaagaatat
    62821 aatcgcttga ctcaacagca accgccaaaa ccagagcaac cagctcctgc accaaaaata
    62881 ggctggaaac aagaaaacgg tatgtggtac ttctacaata ctgatggttc aatggcgaca
    62941 ggatggctcc aaaacaatgg ctcatggtac tacctcaaca gcaatggcgc tatggcgaca
    63001 ggatggctcc aaaacaatgg ttcatggtac tatctaaacg ctaatggttc aatggcaaca
    63061 ggatggctcc aaaacaatgg ttcatggtac tacctcaacg ctaatggtga tatggcgaca
    63121 ggatggctcc aatacaatgg ttcatggtac tacctcaacg ctaatggtga tatggcgaca
    63181 ggatggttcc aatacaatgg ttcatggtac tacct
//
LOCUS       DAVMAH010000002        61370 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVMAH010000002 DAVMAH010000000
VERSION     DAVMAH010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61370
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.002"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..215
                     /locus_tag="VYO94_000062"
     CDS             <1..215
                     /locus_tag="VYO94_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV1758775.1"
                     /translation="WYYLNANGDMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYY
                     VNGSGALAVNTTVDGYGVNANGEWVN"
     gene            complement(445..1425)
                     /gene="dusB"
                     /locus_tag="VYO94_000063"
     CDS             complement(445..1425)
                     /gene="dusB"
                     /locus_tag="VYO94_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV1758776.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1412..2284)
                     /gene="hslO"
                     /locus_tag="VYO94_000064"
     CDS             complement(1412..2284)
                     /gene="hslO"
                     /locus_tag="VYO94_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV1758777.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2449..3876
                     /locus_tag="VYO94_000065"
     CDS             2449..3876
                     /locus_tag="VYO94_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1758778.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGAEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDRTRHYDLLVTNNPIHKRE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            4034..5542
                     /gene="glpK"
                     /locus_tag="VYO94_000066"
     CDS             4034..5542
                     /gene="glpK"
                     /locus_tag="VYO94_000066"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV1758779.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5584..7410
                     /gene="glpO"
                     /locus_tag="VYO94_000067"
     CDS             5584..7410
                     /gene="glpO"
                     /locus_tag="VYO94_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV1758780.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7480..8184
                     /locus_tag="VYO94_000068"
     CDS             7480..8184
                     /locus_tag="VYO94_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1758781.1"
                     /translation="MMSELFGEFLGTLILLLLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8481..8684
                     /locus_tag="VYO94_000069"
     CDS             8481..8684
                     /locus_tag="VYO94_000069"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758782.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(8771..9358)
                     /locus_tag="VYO94_000070"
     CDS             complement(8771..9358)
                     /locus_tag="VYO94_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758783.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            10469..11746
                     /gene="ltrA"
                     /locus_tag="VYO94_000071"
                     /pseudo
     CDS             10469..11746
                     /gene="ltrA"
                     /locus_tag="VYO94_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            12202..13380
                     /locus_tag="VYO94_000072"
     CDS             12202..13380
                     /locus_tag="VYO94_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1758784.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            13694..13825
                     /locus_tag="VYO94_000073"
     CDS             13694..13825
                     /locus_tag="VYO94_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV1758785.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13846..15396
                     /gene="dltA"
                     /locus_tag="VYO94_000074"
     CDS             13846..15396
                     /gene="dltA"
                     /locus_tag="VYO94_000074"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV1758786.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQRHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISDFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15393..16637
                     /gene="dltB"
                     /locus_tag="VYO94_000075"
     CDS             15393..16637
                     /gene="dltB"
                     /locus_tag="VYO94_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV1758787.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16651..16890
                     /gene="dltC"
                     /locus_tag="VYO94_000076"
     CDS             16651..16890
                     /gene="dltC"
                     /locus_tag="VYO94_000076"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV1758788.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16883..18151
                     /gene="dltD"
                     /locus_tag="VYO94_000077"
     CDS             16883..18151
                     /gene="dltD"
                     /locus_tag="VYO94_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV1758789.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            18306..18746
                     /gene="adcR"
                     /locus_tag="VYO94_000078"
     CDS             18306..18746
                     /gene="adcR"
                     /locus_tag="VYO94_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV1758790.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18746..19450
                     /locus_tag="VYO94_000079"
     CDS             18746..19450
                     /locus_tag="VYO94_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1758791.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19443..20249
                     /locus_tag="VYO94_000080"
     CDS             19443..20249
                     /locus_tag="VYO94_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1758792.1"
                     /translation="MLNLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            20259..21764
                     /gene="adcA"
                     /locus_tag="VYO94_000081"
     CDS             20259..21764
                     /gene="adcA"
                     /locus_tag="VYO94_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV1758793.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22891..23664)
                     /locus_tag="VYO94_000082"
     CDS             complement(22891..23664)
                     /locus_tag="VYO94_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1758794.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            23840..25243
                     /locus_tag="VYO94_000083"
     CDS             23840..25243
                     /locus_tag="VYO94_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV1758795.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDLSLLPEIVSEGNVLGRIKEE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLSGSTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLKLESYYSQKN"
     gene            25358..25996
                     /locus_tag="VYO94_000084"
     CDS             25358..25996
                     /locus_tag="VYO94_000084"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV1758796.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            26008..26448
                     /locus_tag="VYO94_000085"
     CDS             26008..26448
                     /locus_tag="VYO94_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV1758797.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSVSCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            26441..26872
                     /locus_tag="VYO94_000086"
     CDS             26441..26872
                     /locus_tag="VYO94_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1758798.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            26863..27333
                     /locus_tag="VYO94_000087"
     CDS             26863..27333
                     /locus_tag="VYO94_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1758799.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            27358..28131
                     /locus_tag="VYO94_000088"
     CDS             27358..28131
                     /locus_tag="VYO94_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1758800.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            28128..28928
                     /locus_tag="VYO94_000089"
     CDS             28128..28928
                     /locus_tag="VYO94_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1758801.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            28987..31281
                     /locus_tag="VYO94_000090"
     CDS             28987..31281
                     /locus_tag="VYO94_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1758802.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSSALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            31291..34407
                     /locus_tag="VYO94_000091"
     CDS             31291..34407
                     /locus_tag="VYO94_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1758803.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYERDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDSNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            34464..36230
                     /locus_tag="VYO94_000092"
     CDS             34464..36230
                     /locus_tag="VYO94_000092"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV1758804.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            36376..37527
                     /locus_tag="VYO94_000093"
     CDS             36376..37527
                     /locus_tag="VYO94_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV1758805.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            37672..38556
                     /locus_tag="VYO94_000094"
     CDS             37672..38556
                     /locus_tag="VYO94_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1758806.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(38674..38751)
                     /locus_tag="VYO94_000095"
                     /pseudo
     CDS             complement(38674..38751)
                     /locus_tag="VYO94_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            39057..39206
                     /locus_tag="VYO94_000096"
     CDS             39057..39206
                     /locus_tag="VYO94_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
                     /protein_id="HEV1758807.1"
                     /translation="MGDQPVQDTETSSALILSHYLDEQDLSEKLKSDLQWFELENKLL
                     NLWEY"
     gene            39194..39484
                     /locus_tag="VYO94_000097"
     CDS             39194..39484
                     /locus_tag="VYO94_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758808.1"
                     /translation="MGVLGYYEAFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKVVKDEVAQI"
     gene            complement(39667..39794)
                     /locus_tag="VYO94_000098"
                     /pseudo
     CDS             complement(39667..39794)
                     /locus_tag="VYO94_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(39889..41220)
                     /locus_tag="VYO94_000099"
     CDS             complement(39889..41220)
                     /locus_tag="VYO94_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV1758809.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(41242..42753)
                     /locus_tag="VYO94_000100"
     CDS             complement(41242..42753)
                     /locus_tag="VYO94_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV1758810.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(42962..43909)
                     /gene="arcC"
                     /locus_tag="VYO94_000101"
     CDS             complement(42962..43909)
                     /gene="arcC"
                     /locus_tag="VYO94_000101"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV1758811.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVEADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(44074..45090)
                     /gene="argF"
                     /locus_tag="VYO94_000102"
     CDS             complement(44074..45090)
                     /gene="argF"
                     /locus_tag="VYO94_000102"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV1758812.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(45148..46381)
                     /gene="arcA"
                     /locus_tag="VYO94_000103"
                     /pseudo
     CDS             complement(45148..46381)
                     /gene="arcA"
                     /locus_tag="VYO94_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
     gene            47137..48816
                     /locus_tag="VYO94_000104"
     CDS             47137..48816
                     /locus_tag="VYO94_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1758813.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGE
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIHWIGNERGH
                     AGDPLWQKMNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMIIEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(48856..50940)
                     /locus_tag="VYO94_000105"
     CDS             complement(48856..50940)
                     /locus_tag="VYO94_000105"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV1758814.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNPLMLFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFQPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            51112..52392
                     /locus_tag="VYO94_000106"
     CDS             51112..52392
                     /locus_tag="VYO94_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV1758815.1"
                     /translation="MVYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VATTKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADTKRLQYEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            52483..55128
                     /locus_tag="VYO94_000107"
     CDS             52483..55128
                     /locus_tag="VYO94_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV1758816.1"
                     /translation="MENIVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTACYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            55212..56081
                     /locus_tag="VYO94_000108"
     CDS             55212..56081
                     /locus_tag="VYO94_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1758817.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            56075..57955
                     /locus_tag="VYO94_000109"
     CDS             56075..57955
                     /locus_tag="VYO94_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1758818.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            58197..58559
                     /locus_tag="VYO94_000110"
     CDS             58197..58559
                     /locus_tag="VYO94_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758819.1"
                     /translation="MPKTKTLAELADVILWSFDFVNAHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFLFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(58611..59075)
                     /locus_tag="VYO94_000111"
     CDS             complement(58611..59075)
                     /locus_tag="VYO94_000111"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1758820.1"
                     /translation="MRRKYKSIALKKELANDSGKKKCHAMKAQAIVTSQGRIVSLDIT
                     VNYCHDMKLFKMSRRNIGQAGKILTDSDYQGPMKIYPQAQTPRKASKLKPLTAEDKAC
                     NHALSKDRSKVENILAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(59419..59595)
                     /locus_tag="VYO94_000112"
                     /pseudo
     CDS             complement(59419..59595)
                     /locus_tag="VYO94_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            59930..>61370
                     /gene="pcpA"
                     /locus_tag="VYO94_000113"
     CDS             59930..>61370
                     /gene="pcpA"
                     /locus_tag="VYO94_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV1758821.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGS"
BASE COUNT        18614 a        11181 c        13369 g        18206 t
ORIGIN      
        1 catggtacta tctaaacgct aatggtgata tggcgacagg ttgggtgaaa gatggagata
       61 cctggtacta tcttgaagca tcaggtgcta tgaaagcaag ccaatggttc aaagtatcag
      121 ataaatggta ctatgtcaat ggctcaggtg cccttgcagt caacacaact gtagatggct
      181 atggagtcaa tgccaatggt gaatgggtaa actaaaccta atataactag ttaatactga
      241 cttcctgtaa gaacttttta aagtattccc tacaaatacc atatcctttc agtagataat
      301 atacccttgt aggaagttta gattaaaaaa taactctgta atctctagcc ggatttatag
      361 cgctagagac tacggagttt ttttgatgag gaaagaatgg cggcactcaa gagactcttt
      421 aagagagtta cgggttttaa actattaagc cttctccaat tgcaagagag cttcaatctc
      481 tgccagggtg ctagcttgcg aaatggctcc acggagtttg gcagcgccag atgttccacg
      541 gaggtagtga ggagcgaggc cacggaattc acgaactgcg acgttttctc ctttgaggtt
      601 aatcaatcgt ttcaagtgtt cgtaggcgat cttcatcttg tcttcaaagg tcaaatcagg
      661 taggatttct cctgtttcaa agtaatggtt gatttggttg aagaggtaag gatttcccat
      721 ggcagctcgg ccaatcatga ctgcgtcagc accaacttct tcgatgcgtt gcttggcttc
      781 ttggacagta cggatatcac cgttggcgat gaatggaatc ttggttagag cttgggcaac
      841 cttgtaaagg gtctcaaggt ctgcgtggcc agtatacatt tgttcacggg tacggccatg
      901 catggcgagg gcagaaacac ctgcagcctc agcagcgagg gcattttcta ctgcaagaga
      961 tgggtccgcc cagccggtac gcattttgac agtaagtggg atatcaagga cagactggac
     1021 cttgttgatg atagagtaga tcttgtcagg atccttgagc cacatagctc cagcttcgtt
     1081 cttcacgatt ttgttgacag ggcagcccat gttgatatcg acgatatcgg tcttagtgtt
     1141 ttcttggata aattctgctg cgcgtgctag gctgtcttca tcgctaccaa aaagttggat
     1201 agagacaggg ttttcgccct catcgatatg aagcatgtgc agggtttttt cgttgttgta
     1261 ttggattccc ttgtcagaga ccatttccat tacaacgagt ccagctccga gctcctttgc
     1321 gatagtacga aaggctgagt tggtcacgcc agccataggc gctaaaacgg tacgattggg
     1381 aatctcaata ttgccaatca taaaaggtgt attaagattt gtcacgaatg agttcctcca
     1441 ggtccttttc atcaaagttg taagtagttt ggcagaattg acaagtgatt tctgccccgt
     1501 ggtcttcctc tttcatttcc tgtaagtctg agcttggaag gctggcaaga gcgttcataa
     1561 agcgttcatg gctacagtca cattggaaac ggatttcttc ttcagaaaga cgcttgtagg
     1621 cttcgtcccc gtagatagcc ttgaggaggg cttcgatatg gtcgtcgctt tcgagaagag
     1681 tagagatagc tggcatttct tggatgcgtt tttcaaagcg agcaatctct tctttcttgg
     1741 ctcctggcaa gacttgaact aggaaaccac ctgcaacctt gaccttgtct tcctcgtcca
     1801 aaaggacatt gaggccgacc gctgaaggcg tttgttggct ttcagtaagg taaaaggcaa
     1861 ggtcttcacc gatttctcca gagatgaggg gagttataga gttgtaagga tttccagtac
     1921 cgtagtctgt gataacgagg aattgaccat ttccaacaaa aggtccgact aggacttcac
     1981 cagtcgcagt ctttttgatg tcaacaccag ggttttgaac atagcctttg acgttcccct
     2041 tggtatcagc gacggtgata atagcaccta gagagctaga tcccaacacc ttaactgtaa
     2101 gtttggtatt tcctttttca ttggctgcga gaatctggct agcgataaga gttcgaccaa
     2161 gcgctacagt tgagctagct tgggtttgat gtttttcttg agcagtgcgg acggtttcag
     2221 tgctatcaag gacaaaagca cgaaaggctc cgctttctga tatagtttta ataattttat
     2281 ccatagctac tattttagca taaaaatgcc caaaggggga gccgtgtgtt tactgatttt
     2341 caggataatg gaccaggaaa tcagcatgaa aataaaaaga gaaacagatt attttagcat
     2401 ttgtcagatt tatgctatgc ttaaggtaga aaatgaaagg gataacaaat gtatttagga
     2461 gatttgatgg agaaagccga gtgtggtcaa ttttcaatcc tttcctttct attacaagag
     2521 tctcagacga ccgtcaaggc tgtaatggaa gaaacaggat tttcaaaagc aaccctaacc
     2581 aaatatgtca ccctgctcaa tgacaaggct ttggatagtg gcttagaact gactattcac
     2641 tcagaagatg aaaatctgcg tctgtctatc ggtgcagcta ccaaggggag agatattcgg
     2701 agcttgtttt tggagagtgc tgttaaatac cagattttgg tttatcttct ctaccaccaa
     2761 cagtttttag cccatcagct ggctcaagaa ttggtgatta gcgaggctac gcttggtcgt
     2821 cacttggctg gtttaaatca gattttgtca gaatttgatt tatccatcca aaatggccgt
     2881 tggcgaggtc cagagcatca gattcgctat ttctatttct gtcttttccg aaaggtctgg
     2941 tcgagtcagg aatgggaagg tcacatgcag aaaccagaga gaaaacagga gattgccaat
     3001 ttagaggaaa tctgcggtgc aagtttgtct gcggggcaga aattggactt ggttctctgg
     3061 gctcacatca gtcaacaacg tcttcgggtc aatgcttgtc agtttcaagt catagaagag
     3121 aaaatgcgag ggtattttga caatatcttc tatcttcgtt tgctgagaaa ggttccgtcc
     3181 ttttttgctg ggcaacatat tccactagga gctgaggatg gtgagatgat gatattcttc
     3241 tcttttctcc tatctcatcg tattcttccc cttcatacta tggagtatat tcttggtttt
     3301 ggagggcagt tggcagattt actgacgcaa ttgattcaag aaatgaagaa ggaggaacta
     3361 ttgggggatt atacagaaga ccatgtcacc tatgaactca gtcagctttg tgctcaagtc
     3421 tatctctata agggctatat tttacaggat cgctacaagt accagttaga gaatcgtcat
     3481 ccatatttac tgatggaaca tgattttaaa gagacagcag aggagatttt tcatgctcta
     3541 cctgcttttc aacaggggac agatttagat aagaagattc tctgggaatg gctccagtta
     3601 atcgaatata tggctgaaaa cggtggccag catatgcgga ttggtctgga tttgacatct
     3661 ggttttcttg tcttttcaag gatggcagcc attttgaaac ggtatttgga atacaatcgt
     3721 tttattacca ttgaagccta tgaccgaact cggcattatg atttgctggt tacaaataat
     3781 cctattcata agagggaaca gacaccagtc tattatttaa aaaacgactt ggatatggaa
     3841 gatttggcag ggattcgcca gttattattc acttaaaagg cttggtgctt ccaggtcttt
     3901 ttgtgaaatt cacacaatct cctcacattt ttttaaaaat taaaaaaagt tgataaacaa
     3961 gaaagcgctt tattttgtat actagtaagt gtaaagagga aacacctcaa gatctttatc
     4021 aggaggacag tacatgtcac aagaaaaata catcatggcc attgaccagg gaactacaag
     4081 ttctcgtgcc atcattttca acaaaaaagg ggaaaaggtt agctcgagtc aaaaagagtt
     4141 tacccagatt ttccctcagg caggttgggt tgagcacaat gccaatgaaa tttggaactc
     4201 tgttcagtca gttattgcgg gtgctttcat cgaaagtggt gtcaagccaa atcaaatcga
     4261 ggcaatcggg attaccaacc aacgtgaaac aacggttgtc tgggataaga aaacaggact
     4321 tcctatctac aatgctatcg tttggcagtc acgccagaca gcacctttgg ctgagcaact
     4381 aaaaagccaa ggttatgtgg aaaaattcca tgaaaagact ggtttgatta ttgatgctta
     4441 cttctctgct accaaggttc gttggatttt ggatcatgta gaaggtgctc aagagcgagc
     4501 agaaaaaggg gaattgctct ttggtactat cgatacttgg ttggtttgga aattgactga
     4561 cggtgcggct cacgtgactg actactcaaa tgcagctcgt accatgcttt ataacattaa
     4621 agaactcaaa tgggatgatg agattttgga aatccttaac attccgaagg ctatacttcc
     4681 agaagttcgt tctaactccg aaatctacgg caagacagct ccattccatt tctacggtgg
     4741 agaggtgcca atctcaggta tggctgggga ccaacaagca gccctctttg gacagttggc
     4801 ttttgagcca ggtatggtta agaatactta tggaacaggc tctttcatca tcatgaatac
     4861 tggggaagag atgcagttgt ctgaaaacaa cctcttgaca accattggtt acggaatcaa
     4921 cggtaaggtt tattatgcct tggaaggttc tatcttcatc gcaggaagtg ctattcagtg
     4981 gcttcgtgac ggtcttcgca tggttgaaaa ttcaccagaa tctgaaaaat acgctcgtga
     5041 ttctcacaac aacgatgaag tttatgtcgt tccagccttt acaggtctag gcgctccata
     5101 ctggaaccaa aatgctcgtg gttccgtctt tggtttgact cgtggaacaa gcaaagaaga
     5161 ctttatcaag gcgactttgc aatctattgc ttatcaagtg cgtgatatca tcgacaccat
     5221 gcaagtggat actcagaccg ccattcaagt actgaaggtg gatggtggtg cagccatgaa
     5281 caacttcctc atgcagttcc aggcggatat tttaggcatt gacattgcac gtgctaaaaa
     5341 cttggaaaca acagctctag gagcggcctt cctagcaggt ttgtcagtag ggtactggaa
     5401 agacttggac gagttgaaac tcttgaacga gacaggagaa ctctttgagc catctatgaa
     5461 cgaatctcgc aaggaacaac tctacaaggg ctggaagaag gctgtgaaag caactcaagt
     5521 ctttgcggaa gtagacgact aatactggca gaataaagcg atttatttag aaagtgtgta
     5581 aatatggaat tttcaaaaaa aacacgtgaa ttgtcaatta aaaaaatgca ggaacgcacc
     5641 ctggacctct tgattatcgg tggaggaatc acaggagctg gtgtagcctt gcaggcggca
     5701 gctagcggtc ttgagactgg tttgattgaa atgcaagact ttgcagaagg aacatctagt
     5761 cgttcaacaa aattggttca cggaggtctt cgctacctca aacaattcga cgtagaagtg
     5821 gtctcagata cggtttctga acgtgcagtg gttcaacaaa tcgctccaca cattccaaaa
     5881 ccagatccaa tgctcttacc agtttacgat gaagatggag caacctttag cctcttccgt
     5941 cttaaagtag ccatggactt gtacgacctc ttggcaggtg ttagcaacac accaactgcg
     6001 aacaaggttt tgagcaagaa agaagtcttg gaacgccagc caaacttgaa gaaggaaggc
     6061 ttggtaggag gtggagtgta tcttgacttc cgtaacaacg atgcgcgtct cgtgattgaa
     6121 aacatcaaac gtgccaacca agacggtgcc ctcattgcca accacgtgaa ggcagaaggc
     6181 ttcctctttg acgaaagtgg caagattaca ggtgttgtag ctcgtgatct cttgacagat
     6241 caagtatttg aaatcaaggc ccgtctggtt attaatacaa caggtccttg gagtgataaa
     6301 gtacgtaatt tgtctaataa gggaacgcaa ttctcacaaa tgcgcccaac taagggagtt
     6361 cacttggtag tggattcaag caaaatcaag gtttcacagc cagtttactt tgacacaggt
     6421 ttgggtgacg gtcgtatggt ctttgttctc ccacgtgaaa acaagactta ctttggtaca
     6481 actgatacag actacacagg tgatttggag catccaaaag taactcaaga agatgtagat
     6541 tatctacttg gcattgtcaa caaccgcttt ccagaatcca acatcaccat tgatgatatc
     6601 gaaagcagct gggcaggtct tcgtccattg attgcaggga acagtgcctc tgactataat
     6661 ggtggaaata acggtaccat cagtgatgaa agctttgaca acttgattgc gactgttgaa
     6721 tcttatctct ccaaagaaaa aacacgtgaa gatgttgagt ctgctgtcag caagcttgaa
     6781 agtagcacat ctgagaaaca tttggatcca tctgcagttt ctcgtgggtc tagcttggac
     6841 cgtgatgaca atggtctttt gactcttgct ggcggtaaaa tcacagacta ccgtaagatg
     6901 gctgaaggag ctatggagcg cgtggttgac atcctcaaag cagaatttga ccgtagcttt
     6961 aaattgatca attctaaaac ttaccctgtt tcaggtggag aattgaaccc agcaaatgtg
     7021 gattcagaaa tcgaagcctt tgcgcaactt ggagtttcac gtggtttgga tagcaaggaa
     7081 gctcattacc tagcaaatct ttacggttca aatgcaccga aggtctttgc acttgctcac
     7141 agcttggaac aagcgccagg actcagcttg gcagatactt tgtcccttca ctatgcaatg
     7201 cgcaacgagt tggctcttag cccagttgac ttccttcttc gtcgtaccaa ccatatgctc
     7261 tttatgcgtg atagcttgga tagcatcgtt gagccagttt tggatgaaat gggacgattc
     7321 tatgactgga cagaagaaga aaaagcaact taccgtgctg atgtcgaagc agctctcgct
     7381 aacaacgatt tagcagaatt aaaaaattaa gaaaaaataa aagaggtgga gggcagcatt
     7441 ccttgtcgcc cgtcccttct ttttaatgga gacagaaaga tgatgagtga attatttgga
     7501 gaatttctag ggactttaat cctgcttctt ctaggaaatg gtgttgttgc aggtgtggtt
     7561 cttcctaaaa ccaagagcaa tagctcaggt tggattgtga ttactatggg ttgggggatt
     7621 gcagttgcgg ttgcagtctt tgtatctggc aagctcagtc cagctcattt aaacccagct
     7681 gtgaccatcg gtgtggcctt aaaaggtggt ttgccttggg cttccgtttt gccttatatc
     7741 ttagcccagt tcgcaggggc catgctgggt cagattttgg tttggttgca attcaaacct
     7801 cactatgagg cagaagaaaa tgcaggcaat atcctggcaa ccttcagtac tggaccagcc
     7861 atcaaggata ctgtatcaaa cttgattagc gaaatccttg gaacctttgt tttggtgttg
     7921 acaatctttg ctttgggtct ttacgatttt caggcaggta tcggaacctt tgcagtggga
     7981 actttgattg tcggtatcgg tctatcacta ggtgggacaa caggttatgc cttgaaccca
     8041 gctcgtgacc ttggacctcg tatcatgcac agcatcttgc caattccaaa caagggagac
     8101 ggagactggt cttacgcttg gattcctgtt gtaggccctg ttatcggagc agccttggca
     8161 gtgcttgtat tctcactttt ctagtttata ctcttcgaaa atcaaattca aaccacgtca
     8221 gcgtcgcctt accgtactca agtacagctt gcggctagct tcctagtttg ctctttgatt
     8281 ttcattgagt attagaaaac aattattttg atagagcttg ggcaagagcc caatttcagc
     8341 aaaaaatgaa gtaaatcttc tcataataaa acgcatcata tcaagcacga aaattccacg
     8401 aggtcaacta cagtcagaaa gctgaacaac aagccaaaac gcccaaaaaa ggcggcaaaa
     8461 agcaagcacc tgcaagcaac gtgccgaaat ggtcaaatcc tgattatgtc aacgaattag
     8521 acccaaaaat cgttgatatg ctagtagaat ttcacaagtc acaaggcact ttggaaactc
     8581 ccgaggcgca agcagaaatc gcccaaaaac gtgaagaaat cgagcaaagg agagctgagc
     8641 ttgagggtaa aaaacaagag cttttgaacc gcttgaacaa atagagtttc gcaagtatta
     8701 tgcttacaaa ttacttgagc aattaactaa aatataaacc ctgcctttat atctaggcag
     8761 ggtttatatt ttagaaattc acataggttg ttacggtttt tacataccca gtatagtttg
     8821 agtttctata gtattcagtg ataaacttcc attttctttg agcaacatgg atataagtac
     8881 ttgttatgta gtatggatat gggctttgtg aatccaagta agactgataa gcttgtatac
     8941 caaaatatgc tccaccaatt attgcacccc atggcccccc caataaagca cctatcctac
     9001 caatcatata actgattcca gcaccagtca tgaagttagc gaatgtgtta gcttgtttat
     9061 tcccatgtat tgtgttgacg taattccaaa cattaggatc gtatgatcta aaagatatat
     9121 ttaggtcgat ttcattcttt tgataagcca tataaaatgc cccattgata tagacgccgt
     9181 cagcacgtcg ttcaatagtg tctacacttc catctggatt gacaacctca agaacttcat
     9241 cgcttaaaat atttacttgc gtatctccga accgcactga tgagccattc tcaaactgag
     9301 cctcaccaga tacaacttta gagtttgccg ataagctatc atcagcaaaa acaaacaagc
     9361 gacggggaaa tgctagacat acagaaaaca gacataacta gcaaacacat gcatttaaac
     9421 atcttagaca taacggaaac tcctttgtat ttttgatttt tttcaacttt tattatacaa
     9481 taaaaccaaa taaaaagaaa gcggtaacaa tatgcttaat gcgaaaattt tttatatatt
     9541 tttatgtttg atcgttatcg aaactacagg cttgttgttg ttgaaaagag gtctcgaaat
     9601 gggttattta gacacagaag ctattatcct cgcagttttt tcatttgctt tttacaacct
     9661 atgttcattc gcttgggtct gctctacaat aaaaaacaat aaaaaataaa tagacgtatt
     9721 ttcaaaaaaa aaaaaaatgc atattcatct tagcaaaacg acgatttaaa tcgtcgtttt
     9781 tttgtagtac gacgggcatg tcgtatatct gaggtgtaag tcctcggtgg gcacctgcta
     9841 ccggtgaacc caatagcgat tcccaagcct gactatcgtg aggtagcagg gagaggaagg
     9901 gatagcgaaa tcgtggctct acgaacagga acgtgatagt aaggcgtata tagcggataa
     9961 ggaggcttca aactctaaag tccaaaaagg tagtcgtaac ctatatgcgt aaatcacgag
    10021 agtaattgaa ttcggactaa ggtttgtgtg aaaagataaa tctttctaga gtctaaagac
    10081 tctgcgtcag atttcctatt ttcactgtaa ccttttaacg tcctcatatc ttgtataaac
    10141 gaggaaagat gtacgactta tcccgtgagg tctcatgagt gctgaaagcg tagtaacaac
    10201 gaatcatgag aagtcagccg aacccatagt agtgaggaaa cttccgtaat ggaagtggag
    10261 cgaaggggtg aatactcaaa tagtctgggg agagactgtt tgaggtctgt cgctagaaag
    10321 agaaaacgac agattgaagt aatcctactt cacttgtgtc tgtaaaacga gaggtctgat
    10381 agaactggag tctgtcacgt attgactaga tgaaggctca ccaatataag atgtccctca
    10441 ggcaccaaaa caagaaagga atacgcacat gtcaaaattg ctagataaga tattatcacg
    10501 cgaaaatatg ctggaagcct acaatcaagt aaaatccaat aaaggctcag ctgggattga
    10561 tggaatgact atcgaagaga tggataatta tctcagacaa aactggcgct tgactaagga
    10621 actgataaaa cagagaaaat ataagcctca accagttctt agagttgaga tacctaaacc
    10681 agacggaggt atccgtcaac taggaattcc aacagttatg gatagaatga ttcaacaggc
    10741 cattgtctaa gtcatgagcc ccatttgtga accccatttc tcagatacga gttatggttt
    10801 cagaccaaat aggtcatgtg aaaaagccat catgaagctc ttagaatact taaatgacgg
    10861 ctatgagtgg atagtggata tagacctaga gaaatttttc gatacagttc ctcaagatag
    10921 attgatgtcc ttagtacata acattatcga agacggagat acggaatcct tgattcgtaa
    10981 gtatcttcat tcaggtgtta tcattaatgg tcaacgttat aaaacactag ttggtacacc
    11041 acagggagga aatttatctc ctctcttatc caatgtcatg cttaatgaat tggacaagga
    11101 attagaaaag aggggacttc gatttgtgcg ctacgcagat gattgtgtga ttacggtcgg
    11161 aagcgaggca gcctctaagc gtgtgatgta ttcagtcagt cgttttattg agaaacggct
    11221 aggtttgaaa gtaaacatga ccaagactaa gattaccaga ccaagagagt tgaaatatct
    11281 aggttttggg ttctggaaat catcagatgg ttggaaaagc cgtccacatc aagatagtgt
    11341 tcggagattt aagtttaaat tgaagaaact aacacagagg aaatggagta tagacctaac
    11401 aagacgtatt gagcaactga atttgtctat tcgaggatgg ataaactatt tctcattggg
    11461 aaatatgaaa agtatagtcg ccagcataga tgagcgcttg cgtactcgcc tacgagtgat
    11521 tatctggaag caatggaaga agaaatcgag acgattatgg ggattgctta agttaggagt
    11581 tcctaaatgg atagcagata aggtatctgg ctggggcgac cattatcaat tagtagctca
    11641 gaagtcggta cttaaacgtg ctatatcaaa accagtcctg gaaaaacgtg gactggtttc
    11701 gtgtttggat tattaccttg aacgacatgc gttaaaagtt agttgaaccg ccgtatgccg
    11761 aacggcacgt acggtggtgt gagaggggct agagattatc ccctactcga ttaactcccc
    11821 tgaaatttat tttaattatg caaatttcac gtatttttga tgctgagacg acgatcctgg
    11881 gaacttttca gatatttttt tgactatcta aatctatcat tagaaaagct tagagcgcca
    11941 aaggatttga gcgtttttct gatttttaag actttttcca gtctcttttt cgattgaaga
    12001 tgtaattatt ctactaacta actaacttct tagtactagc caacaacgat aatcataatt
    12061 cctcctaaaa ttaggaataa taaaggcaat agtttttgtt ttttcatgta aaaaacctca
    12121 cttttgtttt ctgctatttt atgctaaaat attaaaaatc aaatttaatt ccaaagtttg
    12181 taactaaagg gggagcgcta catgtctaat tcatttgtca agttgttagt ctctcaatta
    12241 tttgcaaatt tagcagatat tttctttaga gtaacaatca ttgctaacat atacattatt
    12301 tcaaaatcag taattgccac atcactagtt cctatcttaa taggaatatc ctcttttgtt
    12361 gcgagtcttt tagttccgtt ggttactaaa aggttagcgc taaatagggt tttatcttta
    12421 tctcaatttg gaaagactat attattggcg atactggtag gaatgtttac cgtaatgcaa
    12481 tccgtagcgc ctttggtgac ctatctattt gttgttgcaa tttccatact agatggtttt
    12541 gcagcacccg tttcctatgc tattgtgcca cgctatgcga ccgatttggg taaggctaat
    12601 tcagccttat caatgactgg tgaagctgtt caattgatag gttggggatt aggtggactc
    12661 ttgtttgcaa caattggtct gttacctacc acgtttatca ttttagtctt gtatatcatt
    12721 tctagctttc tgatgttatt tcttcctaac gctgaagtgg aggtgttaga gtcagaaact
    12781 aatcttgaaa ttttgctcaa aggttggaag ttagttgcta gaaatcctag attaagactt
    12841 tttgtatcag caaatttatt ggaaattttt tcaaatacga tttgggtttc ttccattata
    12901 cttgtttttg taacggagtt attaaataaa acggaaagtt actggggata ttctaataca
    12961 gcatactcta ttggtattat aattagtggc ttaattgctt ttaggctatc cgaaaagttc
    13021 cttgctgcta aatgggaaag tattcttttt cctcttgtag ctatggcaat agtgacactg
    13081 actattctat attttccaaa cgcacagatg tttttattat tttcagcttt agttggtatg
    13141 ttatcgcaac taaaagaagt tcctgaaagt gtatttcttc aggaaacagt agaggaaaat
    13201 catttagtta atgtctattc cgttcttgaa gtgatttcta cattagcatt ttcagtattt
    13261 gttttgctaa tgagctatat tactgagagt tttggtatta gcatcagttt ttggctatca
    13321 gccatttgtc tgatgataga agctatttta atttatatca gacgagatta ttttaaatga
    13381 gagagtggtt aaaaagtctt taaaaatcag aaaagcgcat agtatcaggt gttgaaaaaa
    13441 cttgatattg tgtgttttat tatgggaaga tttacttcat tgtctcctga aatggagttt
    13501 tgaagcagga tcactctatt tgaaaatata catagaaaaa ccgcataatc cttaaaataa
    13561 gctgaaatct attggaaaca tacggtaaac aattgaaaag atactatata aagtggtaca
    13621 atggtagaaa aataagctag taagaatcac tcttatttta gcgaaaaatt acagaaatga
    13681 atggtttttc ttgatgaaac agagaaaaga attgtacctc tttcttggtc ggacagcctt
    13741 gtattttctt atctttctag ggctgcttta cttctttagc tatcttggtc agggtcaagg
    13801 aagctttatc tataatgaat tttaacttga aggagaatcc ctattgtgtc aaataaacca
    13861 atagcagata tgattgaaac cattgagcat tttgctcaga cacagcctag ctatcctgtc
    13921 tataatgttt tggggcagag acacacttat ggcgatttaa aggctgattc ggatagtttg
    13981 gctgcagtca ttgaccaact aggcttgcct gagaagtctc ctgtggttgt ttttggtggc
    14041 caagaatatg aaatgttggc aacctttgta gcgctgacta agtcaggtca tgcctacatt
    14101 ccaattgata gccattcggc cttggagcga gtttcagcta ttttagaagt agcagagcca
    14161 agcttgatta ttgccatttc agactttccc ttggagcagg tttctacacc aatgataaat
    14221 ctagctcagg ttcaagaagc ctttgcccaa gggaacaact atgaaatcac gcatccagtc
    14281 aagggagatg ataattacta cattatcttt acttctggta cgactggtaa gccaaaggga
    14341 gtgcagattt cacatgataa tctcctcagc tttacaaact ggatgattac ggataaggaa
    14401 tttgcgacac cgagtcgtcc gcaaatgctg gcacagccac cttattcttt tgacttgtct
    14461 gtcatgtatt gggcaccgac cttggcactt ggtggtacgc ttttcactct tccttcagtc
    14521 atcactcagg actttaagca actctttgcg gctatctttt cattgccaat cgctatctgg
    14581 acatcaacac catcctttgc agatatggcc atgttgtctg aatacttcaa cagtgagaaa
    14641 atgcctggaa tcacgcattt ctactttgat ggtgaagaat tgacggtcaa aacagctcaa
    14701 aaactgcgcg agcgtttccc aaatgcccgt atcatcaatg cttacggccc aacagaagcg
    14761 acagtagctc tgtcagcagt tgccgtgaca gacgagatgt tagcgactct caaacgccta
    14821 ccaatcggct ataccaaggc tgattctcca acctttatca ttgacgagga aggaaataaa
    14881 ctgccaaatg gcgaacaggg agaaatcatt gtttctgggc cagctgtttc aaaaggttat
    14941 atgaacaatc ctgaaaaaac agcagaagcc ttctttgagt ttgaaggtct gccagcctat
    15001 cacacaggcg atgtgggaac catgacagat gagggcttgc ttctctacgg cggacgcatg
    15061 gacttccaga ttaagtttaa cggttaccgc attgagttag aagatgtctc tcaaaacctc
    15121 aacaagtctc gctttatcga atctgctgtc gcagtaccgc gctataacaa ggaccacaag
    15181 gtacaaaatc tattggctta tgtcatctta aaagacagtg ttcgtgagca gtttgagcga
    15241 gatatcgata ttaccaaggc catcaaggaa gacctgacgg acatcatgat gtcctatatg
    15301 atgccatcta aattccttta ccgagacagt ttgccactaa ctccaaatgg aaagattgac
    15361 atcaaaggat tgattaacga ggtgaataag agatgatgga gttttttcaa cagcttcctc
    15421 atttagagcc atatggcaat cctcagtatt ttgtttatgt gattgctgca accttgccca
    15481 tctttatagg cctctttttc aagaaacgct ttgcctggta tgaagtgttg gtaagtctct
    15541 tctttattgt caccatgttg gtgggtggaa agaccaatca actagctgcc ttgggtattt
    15601 acctttgctg ggaaatattg ctcctgcttt tctacaagca ttatcgaaaa agcaaggatg
    15661 gcaagtgggt cttctactta gttagttttc tgtccctact tccgattatc tttgtcaagg
    15721 tgcaaccagc tatcaatgga acgcagtctt tgcttgggtt cttgggaatt tcttacctga
    15781 cctttcgttc ggttgggatt atcatcgagc tgagagatgg agtgattaag gattttaccc
    15841 tctgggaatt cctccgtttc cttctcttca tgccaacttt ctcgagtggt ccaatcgatc
    15901 gctttaagcg atttaatgaa aattatcagg ccattcctga gcgagatgag ttgatggata
    15961 tgctggatga atctgtccgc tatatcatgc ggggcttttt gtataagttt atcctagctc
    16021 atgttttagg agagacctta ctacctcctc tgaagaattt agccttgcag tcaggtggct
    16081 tctttaatct ctatgccttg gcagttatgt atacttttgg tctggagctc ttctttgact
    16141 ttgcaggtta ttctatgttt gctttggcca tctcaaactt gatgggaatc cgtagcccta
    16201 tcaactttaa caagcccttt ttatcaaggg atttaaagga gttttggaat cgctggcata
    16261 tgagtctgtc cttctggttc cgtgactttg tctttatgcg aatggtgatg gtgttaacca
    16321 gaaagaaagt ctttaaaaat cgtaatgtaa cctcaagcat ggcctacatt gtaaatatgc
    16381 tgattatggg attttggcat ggtgtgacct ggtactatat cgcctatgga ctctttcatg
    16441 gactaggctt ggtcatcaat gatgcctggg ttcgcaagaa aaaaacgctc aataaggaac
    16501 ggaaaaaagc agggaaggct gccctacctg agaatcgctg gattcagttg cttggcatgg
    16561 ttgtcacttt ccatgttgtc atgttgtcat tcttaatctt ttctggattc ttgaataatc
    16621 tatggtttaa aaaataaaag gaaataaaat atggatatca aatcagaagt tattgaaatt
    16681 attgatgagt tgtttatgga agatgtttct gacatgatgg atgaagatct ttttgatgca
    16741 ggtgtcttgg atagtatggg aacggttgag ttgattgtgg agattgagaa ccgttttgac
    16801 attcgtgtcc ctgtaacaga gtttggtcgt gacgactgga atacagctaa taaaatcata
    16861 gctggtattg tggagctaca aaatgcttaa acgcttatgg atgatcttcg gaccggtctt
    16921 gatcgctggt ttgttggttt ttctgctcat tttcttttat cctactgaga tgcatcataa
    16981 tctaggagct gaaaagcgtt cagcagtggc tactactatc gatagtttta aggagcgaag
    17041 tcaaaaagtc agagcactat ctgatccaaa tgtgcgtttt gttcccttct ttggctctag
    17101 tgaatggctt cgttttgacg gtgctcatcc tgcggtatta gctgagaaat acaatcgttc
    17161 ctaccgtcct tatcttttag gacagggggg agctgcatcg cttaaccaat attttggaat
    17221 gcaacagatg ttaccacagc tggagaataa acaagttgtg tatgttatct cacctcagtg
    17281 gttcagtaaa aatggctatg atccagcagc cttccagcag tattttaatg gagaccagtt
    17341 gactagtttt ctgaaacatc aatctgggga tcaggctagt caatatgcag cgactcgctt
    17401 actgcaacag ttcccaaacg tagctatgaa ggacctggtt cagaagttgg caagtaaagg
    17461 agaattgtcg acagcagaca atgaaatgat tgaattattg gctcgtttta atgaacgcca
    17521 agcctccttt tttggtcagt tttcggttag aggctatgtt aactacgata agcatgtagc
    17581 taagtattta aaaatcttgc cagaccagtt ttcttatcaa gcaatagaag atgttgtcaa
    17641 agcagatgct gaaaaaaata cttccaataa tgagatggga atggaaaatt atttctataa
    17701 tgagcagatc aagaaggatt tgaagaaatt aaaggattct cagaaaagct ttacctatct
    17761 caagtcgcca gagtataatg acttgcagtt ggttttaaca cagttttcta aatctaaggt
    17821 aaacccgatt tttatcattc cacctgttaa taaaaaatgg atggactatg ctggtctacg
    17881 agaggatatg taccaacaaa cggtgcagaa gattcgctac cagttagaaa gtcaaggttt
    17941 taccaatata gcagattttt ctaaggacgg cggggagcct ttctttatga aggacaccat
    18001 tcaccttggt tggttgggtt ggttggcttt tgacaaggca gttgatcctt tcctatccaa
    18061 tcccacacca gctccgactt accatctgaa tgagcgcttt ttcagcaaag attgggcgac
    18121 ttatgatgga gatgtcaaag aatttcaata gataatataa tatagaagag ttcaagaatg
    18181 aaactagttt tcacgttttt tcttgactct ttttttgctt gtgatataat taactggtaa
    18241 acaaaatgtc aaagaatagt atttttctct taaaaaagag aagtctaaaa ggaaaggagt
    18301 cagatatgag acagctagca aaggatatca atgctttttt gaatgaggtg attttgcagg
    18361 cggaaaatca gcatgaaatc ctaataggtc attgcactag cgaggtggcc ctgaccaata
    18421 ctcaggagca tatccttatg ctcttgtcag aggaatcttt aacaaattca gaattggccc
    18481 gtcgtctcaa tgtcagtcag gcggcagtta ccaaggccat taagtctttg gtcaaggaag
    18541 ggatgttgga aacatctaaa gattctaaag atgcgcgtgt gattttttat cagttgactg
    18601 acttggctcg tccaatcgct gaggagcacc accatcacca tgagcataca cttttaacct
    18661 atgaacaagt ggcgactcag tttactccaa atgaacaaaa agtgattcag cggtttttga
    18721 ctgctttagt aggagaaatc aaataatgag atatattacg gtagaggatt tgtccttcta
    18781 ttatgataag gagcctgttc ttgaacatat caattattgt gttgatagtg gggaatttgt
    18841 taccttgact ggggaaaatg gagcggctaa gacgacgctc atcaaggcta gtcttggaat
    18901 tctgcaacca cgcattggaa aggtggctat ttcaaagaca aatacgcaag gtaagaaatt
    18961 gagaatagcc tatcttcctc aacaaattgc cagttttaat gctggttttc caagtacggt
    19021 ctatgaattt gtcaagtcgg gtcgctatcc gagaaaaggc tggttccgtc gtttgaatgc
    19081 tcatgatgag gagcatatca aggctagtct ggactcagtt ggcatgtggg aacatcgaga
    19141 caaacgcttg gggtctctat ctgggggaca aaagcagcga gcggtaattg cgcgtatgtt
    19201 tgcttctgac cctgatgtgt ttatcctaga cgagccgaca acggggatgg atgcaggaag
    19261 taaaaatgaa ttttacgaac tcatgcacca cagcgcccat catcatggca aggctgtttt
    19321 gatgattacc catgaccctg aagaagttaa ggattatgcg gatcgcaata ttcatctagt
    19381 ccgtaaccaa gactcgccat ggcgttgttt caacgttcat gagaatggcc aggaggtggg
    19441 ccatgcttaa tttattatct tacgacttta tacaacgcgc ctttttggcg gttattgcta
    19501 tgagtctttt ctcaccggta ttgggaacct tcctcatctt gcgtcgtcag agtttgatga
    19561 gtgataccct tagccacgtc tcactttcag gtgtagcctt tggtctggtt ttggggattt
    19621 ctccaactgt ttctactatt gccattgtct tgattgcggc ggtctttctg gagtatctcc
    19681 gtacggttta caagagcttt atggaaatcg ggacagctat cctcatgtca acaggtctgg
    19741 ctgtttctct gattgtcatg agcaagggta aaagctcgag ttcaatgagt ttggaccaat
    19801 atctctttgg ttcgattgtg actatcagtg aagaacaggt catttccctc tttgtcattg
    19861 cggcggttgt tttgattttg acctttctct ttcttcgtcc tatgtatatc ttaacttttg
    19921 acgaagatac ggcctttgtg gatggcttgc cagttcgtac catgtccatt ctttttaaca
    19981 tggtgacagg ggtggctatt gcccttatga ttcctgcagc aggagctctt ctggtatcga
    20041 ccattatggt cttgccagct agtattgccc tgcgtctggg gaaaaacttt aaatcggtta
    20101 tgctgcttgc cagtgcgatt ggctttttgg gaatggtagc aggactttac atttcctact
    20161 atgcagaaac acctgcaagt gcaagtatta ccattatttt tgtaactgtc tttatactaa
    20221 tcagtttagt aagacgtttt atcaaatagg agacgaacgt gaaaaaaatt agcttattac
    20281 tagccagtct atgtgccttg tttttagtgg cttgttccaa tcaaaaacag gcagatggta
    20341 aactcaatat cgtgacaacc ttttaccctg tctatgaatt taccaagcaa gtcgcaggag
    20401 atacggctaa tgtagaactc ctaatcggtg ctgggacaga acctcatgaa tacgaaccat
    20461 ctgccaaggc agttgccaaa atccaagatg cagatacctt cgtttatgaa aatgaaaaca
    20521 tggaaacatg ggtacctaaa ttgctagata ccttggataa gaaaaaagtg aaaaccatca
    20581 aggcgacagg cgatatgttg ctcttgccag gtggcgagga agaagaggga gaccatgacc
    20641 atggagaaga aggtcatcac catgagtttg acccccatgt ttggttatca ccagttcgtg
    20701 ccattaaact agtagagcac atccgcgaca gcttgtcagc agattatcct gataaaaaag
    20761 agacctttga gaagaatgca gctgcctata tcgaaaaatt gcaagccttg gataaggctt
    20821 acgcagaagg cttgtctcaa gcaaaacaaa agagctttgt gactcaacac gcagccttta
    20881 actatcttgc cttggactat ggactcaaac aagtcgcaat ctcaggactt tctccagatg
    20941 cagagccatc agctgctcgc ttggcagaat tgacagagta tgtcaagaaa aataaaatcg
    21001 cctatatcta ttttgaagaa aatgcctcac aagcccttgc taacacactt tcaaaagaag
    21061 caggtgtcaa aactgatgtc ctcaatcctt tagaaagtct gacagaagag gacaccaagg
    21121 ctggagaaaa ttacatctct atcatggaga aaaacctcaa ggctttgaaa caaacaacag
    21181 accaagaagg cccagcgatc gagcctgaaa aggcagagga taccaagaca gtccaaaatg
    21241 gttacttcga ggatgcagct gtcaaggacc gcaccttgag tgactatgca ggtaactggc
    21301 aatcagttta tcctttcctt gaagacggca cgtttgacca agtctttgac tacaaggcta
    21361 agttgactgg taagatgacc caggctgagt acaaggctta ctatacaaaa ggctatcaga
    21421 cagatgtgac taagattaac attactgata atactatgga atttgttcaa ggtggacaaa
    21481 gcaagaaata tacttacaag tatgtcggta agaaaatttt gacttacaag aaaggcaatc
    21541 gtggcgtgcg tttcctcttt gaagccacag atgctgacgc tggacaattc aagtatgttc
    21601 agtttagtga ccacaatatc gccccagtta aggcagaaca tttccatatc ttctttggag
    21661 gcacaagcca agaagccctc tttgaagaaa tggacaactg gccaacctac tacccagata
    21721 acctatctgg ccaagaaatc gctcaagaaa tgttggcgca ttgatgagaa atcgactagt
    21781 tcataagagc tagtcggttt tttgatacta gatggctaac ttcattatag acctttcaga
    21841 actaagggaa cctgaaaaaa taaataaaac tcttgaaata tctgggctta tatgctagaa
    21901 tgtagttagt gtataaggtt cattagaaca ccaaagcccc taactagtgc catagttaag
    21961 ggcttttttg acgtatctta gcgatttaac gggtgtttat aggctagtca gtcggtctac
    22021 ttcttaccat ctagccattt gcagacgaaa tacaagataa ttccagctat aacatctgct
    22081 ataatagtaa gagcaagctc tggtataagg ctcattagtt tcacctcctc tcacgaaccg
    22141 taaggaacgt aatcggtaac cgatgacaaa aatagtatat cacattaaat ttagatcatc
    22201 aacattgctt aatgcttgaa atattaggac ttatatgcta aaatgtagtt aattgataag
    22261 gttcattaga acaccaaagc ccctaactat ggccgtagtt aagggctttt ttgacgtatc
    22321 ttagcgattt aacgggtgtt tataggctag tcagtcggtc tactccttac tatctagcca
    22381 tctgcagacg aaatacaaga taattccagc tataacatcc gctataatag taagagcgag
    22441 ctctatgata aggctcatta gtttcacctc ctctcacgaa cccataggaa cgtaatcggt
    22501 aaccgatgac aaaaatagta taccacaata catttagatc atcaaggtca cttaattctt
    22561 gaaatatagg gtctaggcga caaagtcttt aaaatcagaa aaacgcataa tatcaggtgt
    22621 gcaaaaactt gatactatgc gttttattgt gggaatattt gccccatttc tcctgaaatt
    22681 gagtttttgt ccagcctctg tttttagggt tgctaagaaa ataatgtcat gtggtgaata
    22741 tttgtaaatc agtcagcaga cagaacgata ctcttcgaaa atctcttcac atcatgtcag
    22801 cttcgtcttg ccgtgtccat gggggccttg acttcatcag ttttcaaatc tgtactgtga
    22861 gcaagctgag actagcttcc tatttgattt ttattgaata tcagaaaccc attctccatc
    22921 aaataattcg actgcgtcta ataatttttg gtctggcaag gtgtcagaaa taaaggttgt
    22981 gtatttggat aggggattaa ttttaaaaaa tccagtcttg taaaatttag aactatcaat
    23041 cagtaagatg gtttcatggg ctttgtcaat aatattcttt tttgaaatag cttggctgag
    23101 agaagcttca taaacatatt ggtcatcaat acctcttgct gaacaaaatg ctaaatcgat
    23161 attaaaatga tctaataaag aattttcctt atcatagttg accacggaac aggattgatg
    23221 tttgacctcg ccagatgtga taaagatttt ggagctatct ttaacagttt cagatagggt
    23281 ttgtgcagta tgtaaaccat ttgtaaaaat aatcaaatta tcaagttcag aaagataggg
    23341 acaaagttcg tagacagtag tactagaatc tagatagata cacataccag accgaataaa
    23401 gtctttagcg agactagcga ttagtctttt ttgcctagta ctttctcctt cccgtatttg
    23461 atgagaaagt tcaattgtgt tcatagagga cagggtcacg tatccgtgct ttcttttgat
    23521 aagaccttga ttttctaaga aaattaaatc acgacgtaag gtacttgtgc tggagaaagt
    23581 gatttctgcc agctctttta cggcaattct ttttttcttt ttgataattt caatcaattc
    23641 aagtacacgt tcatctttta tcataagctc ctcctaattt atcatttcaa ctatattata
    23701 gcacaaattg gaggaatgtg aattattttt atgaatattg ggttaacatt tgaacattat
    23761 tcaagtaagc gttcacatat tgaaaaaata aaacgtgggg attataataa acttaatcaa
    23821 ggacgaagag agaagaaaaa tggaagcggt tttagcaata gatttaggtg cgacttctgg
    23881 aagagcaatc gttggttacc tttctgaaaa taaactagta atggaagaaa taaatcgctt
    23941 ttctaatcta cctattagag taaaagggca tttatcttgg gatattgact ttctactagc
    24001 taaaattctt gaaagtatcc gcttggctaa tactagttac aagattttat ctatcggtat
    24061 tgacacatgg ggagttgatt ttggactgat tgataatgaa ggtaagctgt tatcacaacc
    24121 tgttcattat cgtgatgaaa gaacaaaggg agtgttaaag gaaatatctg aaatgactga
    24181 attagaaaaa ctgtattcag agacaggaaa tcagattatg gagataaata ccttgtttca
    24241 actctttaag gcacgtcaag aatctcctga ctctttctat aagaccaata agattctttt
    24301 aatgccagat ttgtttaatt atctcttgac aggtaagttt gctacagaaa aaagcattgc
    24361 ttcaacaact caattatttg atcctaggag tcaaaattgg aatcagaata tcttaaaact
    24421 atttgaattg gatttatctt tacttcctga aattgtttca gagggaaatg ttcttggaag
    24481 gataaaagag gagtatggtt taggcgatat tcctgttgtg aatgtttgta gtcatgatac
    24541 agcaagcgcg attgtctcag tacctaagac agaaggtagt ttatttattt catcaggtac
    24601 ttggtctttg gttggagtgg aacttacttc accgcttctt actaccgaat ccttcagtta
    24661 tggatttaca aatgaagtcg gtaaagatgg agtgattaca tttctgaaga attgtacagg
    24721 gttgtggatc atagaggaac taagacgttc atttgaacga agagggaaag cctattcttt
    24781 tgatgatatt aggacaatgg tggagaaaga aaaagaaaat cttcctctga ttgatactga
    24841 atcaactgaa tttgcaacag aatctgatat gcacaagact ttgacagaat atctagctta
    24901 tcatcatgaa actagagagt ggacagatgg acaactattt aagattgttt atgaaagcct
    24961 agctgaaacg tataggaaag cgatagagtt attagaagaa ctaactcata aggtttataa
    25021 gaggatatat gtgattggag gaggtgctag agccagttat tttaaccaaa tgattgctga
    25081 tagaactggt aaagaagttc tatcaggttc aactgaggct acagctgtgg ggaatattgt
    25141 tgtgcagctc atagctatgg gacaattaaa agggatggaa gaagctcacc atgttattga
    25201 ggagttccta aaattagaga gttattactc ccaaaagaat taaaaagatt gagagtttgt
    25261 aaatttgcct ccctccccct tcttaagttt tgtacaagaa ggggggataa ttggtgaatt
    25321 gaaaaatctt tagtgttttg atatgaggag gacaaggatg tcagatgtaa aacaagaatt
    25381 aattaaatat ggtaagaagc tagtagaaac agatttgacg aaaggaacag gtgggaatct
    25441 cagcgttttc gatcgtgaaa aacaattgat ggcaattacc ccgtcgggta ttgatttctt
    25501 tgaaatcaaa gaatccgata ttgtagtgat ggatattaat ggaaatgttg tagagggaga
    25561 acgcttgcca tctagcgaat ggtatatgca tttgattcaa tatcaaactc gtgatgatat
    25621 cgatgcaatt atccatgctc atacaactta tgcaacagta ttagcttgtc tcagagaacc
    25681 acttccagcg agtcattata tgattgcagt ggcagggaaa gatgttcggg tagctgagta
    25741 tgcaacatat ggcacgaaag aattggctgt gaatgcagct aaagcaatgg aaggtcgtag
    25801 agcagtttta ctagcgaatc atggaatttt agcaggtgca caaaatttat tgaatgcatt
    25861 taatattgtt gaagaagttg aatattgtgc aaaaatttat tgtttagcta agaattttgg
    25921 agagccagta gttcttcctg atgaggagat ggaattgatg gcagaaaaat ttaaaacata
    25981 cggtcagaga aaatagggag gatattaatg ttaaaacata taccgaaaaa tatttctcca
    26041 gatttattga agactttaat ggaaatggga catggagatg aaatagtatt agctgacgcg
    26101 aattaccctt ccgtctcatg tgcgaataaa ttaattcgtt gtgatggtgt aaatattcca
    26161 gaattattag attccattct gtatttaatg ccattagata gttacgtcga tagttcaatt
    26221 cagtttatga acgttgtttc gggtgatgat attcctaaga tatggggtac ctatagacag
    26281 atgattgaag gtcatggtac agatcttaaa acgattactt atcttagaag agaagacttt
    26341 tatgaacgta gtaagaaagc ttatgctatt gttgctacag gagaaacttc actttatgct
    26401 aatattatcc ttaagaaagg agtagttgtt gaaagagaaa atgtttaata gaggaatttt
    26461 agttgccagt catggtaatt ttgctagcgg agctctcatg accgcagaaa tgtttgttgg
    26521 tgagacaaca aatgatagag ttaggacatt aggtttgatg cctggagaga atattgtaga
    26581 gtttgagcat tattttaaaa atcaagtgga tgaactgtta gactcaaatc aagaggttat
    26641 cgttttgact gacttgattg gaggaagtcc taataatgtt gctttgtcac ggtttttaaa
    26701 tttggattca gttgatattg taacagggtt taatatccct ctcctagtgg aattaatatc
    26761 aaattatgat tcaaaaatca atttagaaga aattgttcac aatgctcaaa atagtttgtt
    26821 taatgttaaa caacaactta acgtagagga ggaagaagat ttatgtctat agagtttgtt
    26881 cgtattgatg accgtctggt acatggtcaa gttgtcacta cgtggctaaa aaagtatgat
    26941 attgagcaag ttatcattgt taatgatcgc atctcagaag ataaaacacg acaatctatt
    27001 ttaaagattt ctgcaccagt aggtttaaaa attgttttct ttagtgtaaa acggtttgtg
    27061 gaagttttaa actctgtgcc aataaaaaag agaacaatgc tgatatatac aaatccaaaa
    27121 gatgtgtatg attctattga aggaaattta aaattggagt acctcaatgt aggacagatg
    27181 agtaaaacgg aggaaaatga aaaggtaacg ggaggtgtag ctctaggtga agaagacaaa
    27241 tattatttta agaaaatagt tgataaggga acgagagttg aaattcaaat ggttcctaat
    27301 gataaagtta caatgttgga aaaattttta taaaaataat ttaaggaggt acagtatatg
    27361 ctattcacac aagcattact ggtgacatta gttgggatta ttgccactat tgactataat
    27421 ggaccgttat ttatgattca ccgtccgtta gttacaagtg caatggttgg cttagtctta
    27481 ggagatttca cccaaggtgt tcttattggt tcagctcttg aattaacttg gctcggtgta
    27541 acaggtattg gaggttacac tccaccagat actatttcag gtgcgattat tggtactgca
    27601 tttggtattt tatctggtca aggagaaact gctggtatcg ctatagcagt tccaattgca
    27661 gttgctaccc aacagttgga tgttcttgca aaaactttag atgtttattt tgtgaaaaaa
    27721 gctgataatg atgctaaaaa cggagattat tcaaagatcg gtttttatca ttattcaagt
    27781 ttagttttaa tcacgttatt taaaattgta ccaattttcc tagctattat gcttggaggg
    27841 gaatatgtgg cagacttgtt tgctaaggtt ccaccaatcg ttatgcaggg acttaactct
    27901 gcaggtgctt tactaccttc aattggtttt ggtatgcttt taaatatgat gctcaagaaa
    27961 aatatgtggg tattcttgtt gattggattc atttgttctg tgtatggagg aatgtcaacc
    28021 attgggatct cactagttgg tattgcggta gcatacttct acgatatgat tggaagtaaa
    28081 ccacaagaaa caacttcaag tagtgatgtt gaggaggatc ttgatctatg atgaataata
    28141 aagtaactaa agttgaactt aaaaaagttt tcaaacgaag ttttatgtat ggttcttcat
    28201 ggaactatga gagaatgcag aacctaggtt ttctatatac aattcttcca gtattgaaaa
    28261 aactataccc agacaaagat tcagcttctc ctgcaatgaa acgtcacctt gagtttttca
    28321 atactcatca aacagcggca ccatttattc ttggagttac ttccgctatg gaagaacaag
    28381 aaggaaatga aggtgcagct tcaattactg gtattaaagt tggcttgatg gggccactgg
    28441 ctggtctagg agatagtttg ttctggctga cactagttcc tatctgtttt agtattggtg
    28501 cgtcttattc taaagacggc ggtgctttag gtatctttat cgccttaata ttgtttaata
    28561 ttattaatat tcctgttaaa tatttcggtt tgaaatatgg gtatactaag ggttctagtc
    28621 ttatccaaga aaataataca aaaggaacat tgaatcgcgt tacgagtatg gcgacagcat
    28681 tagggctagt actagtgggt ggtttgattc catcaatggt tggtattaat tttggattag
    28741 aatttaagca gggggaactt gttatttctg ttcaagaaat gattacaaaa ttaattccag
    28801 gatttatccc tatggctttg actttattaa tgtgtaaatt aattagaaaa ggaaagaatc
    28861 cggttgtact aatctttagt gttatggcta ttggagttat cctagttgtt ttaggaattt
    28921 tgaagtagta gaaagtgtgg aggtggtatt tgggatatca cctccatttt ggaagagagg
    28981 taaagagtga aattatggta taagaaagct gccgcaaatt ggaatgaagc cttgccgatt
    29041 gggaacggtc atttaggtgg tatgatttat ggttcagcta caaaagaatg tattcaacta
    29101 aacgatgaga ctatttggta tagaggaaag tcagatagaa ataatccaga ctcactattg
    29161 catcttaaaa aaattcggga atatctttta gatggagaaa ttcagaaagc cgaagaattg
    29221 ataaagttaa caatgtttgc taccccaaga gatcaaagcc actatgaatt acttggggaa
    29281 ctttacattg agcatataga tattcagtct tctgctcttt cattgtatga aagagagcta
    29341 gatttagata cagctatttc taatgttgtg tttgagccta atagttgtaa tttacaaata
    29401 aaaagagaat attttacgag ttttaataag aatattttat gctgccgtat agtgtcatca
    29461 gttcaaaaca cattaaattt aaacattaat ttgggtagaa ataaacggtt taatgacgaa
    29521 gtatctaaac tggattcaag tacaatttta atgtcggcct ctgctggagg tagaaaaggt
    29581 gttcagttta aagtagtatg tcattctaaa gttacggatg gtgaagtaag tgtattggga
    29641 gagacaatag ttattcggaa tgctacagag gtatttcttt atctcaaatc aatgacggat
    29701 tattggggaa atatagatat ttcttctctt cagggagaat ttagtagtat tgattacttt
    29761 acagaaaaag atgaacatgt aaaaaaatat caggagcaat ttaatagagt tgattttaaa
    29821 ctagactata gtaaagattg tcttagcatt ccaacgaatc tacttcttga aaacactaaa
    29881 aagtatagta actacttgac taacttgtta tttcattatg gaagatatct gttaatatcg
    29941 tctagtcaac cgaatggttt acctgccaat cttcaaggaa tatggtgtga tgaattaaat
    30001 ccaatttggg gttctaaata tacgattaat attaatactc aaatgaatta ttggatggta
    30061 ggtccatgtg atttaccaga agtagaatat ccattatttg atatgctcga aagaatgaga
    30121 gaaccgggaa gactaaccgc taagaaaatg tatggagcta gaggttttac agcacatcat
    30181 aatacggatg gttttggcga tacggctccc caatctcatg ccatgggggc tgcaatttgg
    30241 gtattaacta ttccatggtt atgtactcat atttgggaac actatttata tttccaagat
    30301 gagcgtattc ttacggaaca ttttgaaatg ataaaagaag catttctttt ctttgaagat
    30361 tatttatttg aggtggatgg ctacttgatg acaggtccaa gtgtctcacc ggaaaataaa
    30421 tatcgcttaa aaaatggtat tgaaggaaat gcttgtctat catctacaat tgataatcaa
    30481 attctaagat atttttgtga ttcatgcatt ggcattgcaa aacaattagg agacaattcg
    30541 gattttatta gtcgtgtgaa ggagttaaaa aagaaactac ctaaaacaaa aataggtagt
    30601 aatgggcaaa tccaagaatg gttagaagat tatgaagaag tagagcctgg gcatagacac
    30661 atttcacctc tatttgggct ttatccttat aatgagattg atattcataa aactccggaa
    30721 ttagcagaag cagctaaaat cactatcaat aggagattat caaacgctaa ctttttatct
    30781 tcacaggaga gggagcaagc gattaataat tggttagtaa gtggtttgca tgctagtaca
    30841 caaacaggtt ggagtgctgc atggctgatt catttttttg cgagactata tcaaggtgaa
    30901 cctgcttata accagattaa tggtttgtta aataatgcga ctcttggcaa tttatttctt
    30961 gaccatccac catttcaaat tgatggtaat ttaggtttgg tgagtggaat ttgtgaatta
    31021 ttagtacaga gtcatcataa ttggttatca ctaattccag ctttaccttc tgcttggtca
    31081 gaaggagaag tgaaaggttt cagagtaaga ggaggatata aggtatcgtt tgcttggaaa
    31141 aatggggata taacattcct aaaattggaa ggaggaaaca aagatcaaaa agtaagagta
    31201 agaatatatg gcaaaaatac tgatgtacaa aatattgaat tggtatttaa ttcagaaaaa
    31261 attattgagt taaattttta ggtataagtc atgaataaag aaaaaataaa aagaaaatta
    31321 atcacaatac tgtttgtatg tattgggatg ttatgttttg gattgttagc aggagttaag
    31381 gctgataatc gtgttcaaat gagaacgacg attaataatg aatcgccatt gttgctttct
    31441 ccgttgtatg gcaatgataa tggtaacgga ttatggtggg ggaacacatt gaagggagca
    31501 tgggaagcta ttcctgaaga tgtaaaacca tatgcagcga ttgaacttca tcctgcaaaa
    31561 gtctgtaaac caacaagttg tattccacga gatacgaaag aattgagaga atggtatgtc
    31621 aagatgttgg aggaagctca aagtctaaac attccagttt tcttggttat tatgtcggct
    31681 ggagagcgta atacagttcc tccagagtgg ttagatgaac aattccaaaa gtatagtgtg
    31741 ttaaaaggtg ttttaaatat tgagaattat tggatttaca ataaccagtt agctccgcat
    31801 agtgctaaat atttggaagt ttgtgccaaa tatggagcgc attttatctg gcatgatcat
    31861 gaaaaatggt tctgggaaac tattatgaat gatccgacat tctttgaagc gagtcaaaaa
    31921 tatcataaaa atttggtgtt ggcaactaaa aatacgccaa taagagatga tgcgggtaca
    31981 gattctatcg ttagtggatt ttggttgagt ggcttatgtg ataactgggg ctcatcaaca
    32041 gatacatgga aatggtggga aaaacattat acaaacacat ttgaaactgg aagagctagg
    32101 gatatgagat cctatgcatc ggaaccagaa tcaatgattg ctatggaaat gatgaatgta
    32161 tatactgggg gaggcacagt ttataatttt gaatgtgccg cgtatacatt tatgacaaat
    32221 gatgtaccaa ctccagcatt tactaaaggt attattcctt tctttagaca tgctatacaa
    32281 aatccagctc caagtaagga agaagttgta aatagaacaa aagctgtatt ttggaatgga
    32341 gaaggtagga ttagttcatt aaacggattt tatcaaggac tttattcgaa tgatgaaaca
    32401 atgcctttat ataataatgg gagatatcat attcttcctg taatacatga gaaaattgat
    32461 aaggaaaaga tttcatctat attccctaat gcaaaaattt tgactaaaaa tagtgaggaa
    32521 ttgtctagta aagtcaacta tttaaactcg ctttatccaa aactttatga aagagatggg
    32581 tatgctcagc gtgtaggtaa ttcctggtat atttataata gtaatgctaa tatcaataaa
    32641 aatcagcaag taatgttgcc tatgtatact aataatacaa agtcgttatc gttagatttg
    32701 acgccacata cttacgctgt tgttaaagaa aatccaaata atttacatat tttattgaac
    32761 aattacagga cagataagac agctatgtgg gcattatcag gaaattttga tgcatcaaaa
    32821 agttggaaga aagaagaatt agagttagcg aactggataa gcaaaaatta ttccatcaat
    32881 cctgtagata atgactttag gacaacaaca cttacattaa aagggcatac tggtcataaa
    32941 cctcagataa atataagtgg cgataaaaat cattatactt atacagaaaa ttgggatgag
    33001 aatacccatg tttataccat tacggttaat cataatggaa tggtagagat gtctataaat
    33061 actgaaggga caggcccagt ccctttccca acaccagata aatttaatga tggtaatttg
    33121 aatatagcat atgcaaaacc aacaacacaa agttctgtag attacaatgg agaccctaat
    33181 agagctgtgg atagtaacag aaatggtaat tttaactctg gttcggtaac acacactagg
    33241 gcagataatc cctcttggtg ggaagtcgat ttgaaaaaaa tggataaagt tgggcttgtt
    33301 aaaatttata atcgcacaga tgctgagact caacgtctat ctaattttga tgtgattcta
    33361 tatgacaata atagaaacga agttgctaag aaacatgtta ataatttgtc gggtgaatct
    33421 gttagtctag atttcaaaga aaaaggagca agatatatta aagttaaatt actaacgagt
    33481 ggagtgcctt tgagtttagc agaagtagag gtttttagag aatcagatgg taagcaatct
    33541 gaagaggata tagataaaat aacagaagat aaagtagtct ctacaaataa ggtagctact
    33601 caaagttcaa ccaattatga gggtgtagct gctttagcag ttgatggtaa taaagatgga
    33661 gattacggac atcattcggt gactcatact aaggcagatt ctaacgcttg gtggcaggtc
    33721 gatctgggag aagagtttac ggtttctaaa gttgatattt ataatagaac agatgccgaa
    33781 cctcagcgtt tatctaattt tgatgttatt tttctatctt catcaggaga agaagttttt
    33841 agaagacatt ttgataaagt agttgatggt ttgttatctt taaaagtacc ttctgtaggg
    33901 gctaagctag tcaaaataga attaaaatca gcagctattc cgttaagttt agcggaagtt
    33961 gaagtctatg gttcaaagag aactccgaag aaactttcta atattgcatt aaccaaagaa
    34021 actcgacaga gttcaacgga ttacaatggt ttttctcgtc tagcagttga tggaaataaa
    34081 aacggagatt atggtcatca ttcagtgact cataccaaag gagattctcc ttcatggtgg
    34141 gagatagatt tagcacaaac cgaagaatta gaaaagttaa ttatttataa tagaacagat
    34201 gctgaaattc agagattatc aaattttgat attattatat atgattcaaa taatcatgaa
    34261 gtttttaaac aacatattga cagtttagaa agcaataatc tatccataga cttaaaaggg
    34321 ctgaagggaa aaaaggttag aatttctttg agaaacgcag gaattccttt aagtttggca
    34381 gaggtagagg tttatactta taagtaattt taaaaattat catcggtagt atgaaagaaa
    34441 cagaaaaata agaggaaaat agtatgattc aacatccacg tattgggatt cgtccgacta
    34501 ttgatggtcg tcgtcaaggt gtacgcgaat cacttgaagt gcaaacaatg aacatggcta
    34561 aaagtgtggc agatttgatt tcaagcacat tgaaatatcc agatggggaa cctgtggaat
    34621 gcgtgatttc tccatctact attggccgtg ttccagaggc tgcagcttcc catgagttgt
    34681 ttaaaaaatc aaatgtttgc gcaacaatta cagttacacc atgctggtgt tatggtagtg
    34741 aaactatgga tatgtctcca gatattcctc atgctatttg gggatttaat gggacagaac
    34801 gcccaggagc tgtctatctt gcagctgtac tagcttcaca tgctcaaaaa gggattccag
    34861 cctttgggat ttatggtaga gatgttcagg aagctaatga tacagatatt ccagaagatg
    34921 tcaaagaaaa acttttacgt tatgcgcgtg cagctcttgc aactggcttg atgagagaca
    34981 ctgcttacct atcaatgggt agtgtttcga tggggattgg tggttctatt gtaaatccgg
    35041 atttcttcca agaatactta ggaatgcgaa atgaatcggt agatatgacg gagttcacac
    35101 gccgtatgga ccgtggtatt tacgaccctg aagagtttga acgtgctatg gtttgggtaa
    35161 aagaacatat caaagaagga gttgaccgaa atcgtgagga tttgattctt tctaaagaag
    35221 agaaagaaaa acaatgggaa tttgttatta agatgttcat gattggacgt gacttaatgg
    35281 ttggtaaccc aagacttgct gaacttggtt ttgaggaaga agcagttggt caccatgctt
    35341 tagtagctgg tttccaaggt caacgtcagt ggacagacca tttcccaaat ggggacttta
    35401 tggaaacttt cctcaatact cagtttgact ggaatggtat tcgaaaacca tttgtatttg
    35461 cgacagagaa tgattcacta aatggtgtgt ctatgctctt taattatcta ttaacaaata
    35521 ctccacaaat ctttgctgat gtgcgtactt attggagccc agaggctgtt aaacgtgtaa
    35581 cgggacatac tttagagggt cgtgctgcag ctggcttctt acatctaatc aattctggtt
    35641 cttgtacatt ggatggtaca ggtcaagcta ctcgagatgg caaacctgtt atgaaaccat
    35701 tctgggagtt ggaagaaagt gaagtgcagg ctatgcttga aaatacagac ttcccaccag
    35761 caaaccgcga atacttccgt ggaggaggat tctcaactcg tttcttgacg aagggggata
    35821 tgccagtaac aatggtacgt ctcaatcttc taaaaggggt tggtccagtg ctacaaattg
    35881 cagaaggtta cacacttgaa cttcctgaag atgttcacca tactttagat aatcgtacag
    35941 atccaggatg gccaactact tggtttgctc cacgtttgac aggaaaaggt gctttcaagt
    36001 ctgtctatga cgtcatgaat aattggggag ctaatcacgg agccataaca tatggacaca
    36061 ttggagcaga cttgattacc ttggcttcta tgttgagaat tcctgtcaat atgcataatg
    36121 tacctgagga agatatcttt agacctaaaa attggtcctt atttggaaca gaagatctag
    36181 aatcagcaga ctatcgtgca tgtcagttgt tgggaccact acataaataa aacttgttta
    36241 tataggaggt gaacttacgt ccctcctatc cttttaaaaa gatttgttaa acaattcaca
    36301 aataattgaa aacgaataca aaaagtaata taatgatgtt aaatagatag cgcggaggcg
    36361 caggaggaaa attatatggc tatattttat gttccggcag tcaaccttat tggaaaaggt
    36421 gttgtaaatg aagtggggcc ttatatcaag gaacttggct ataaaaaggc acttttggtg
    36481 acagataagt acatcgaagg cagtgatatt ttacctaaga ctttaaaacc actggataca
    36541 gaaggaatcg aatatgtcat ctttagcgat gtagagccaa accctacttg taaaaatgtc
    36601 acagatgggg tagctgcttt gcaagaacat ggctgtgact ttatcatcag tcttggcggg
    36661 ggttctccac aggatgcagc tagttgtatt tctatcatgg ctacaaatgg tggaaaacca
    36721 caggattatg aagggcttca taagtctgct aaaaaaggct tgccagttgt ggctatcaat
    36781 acaacggcag gtacatcagc agaaattacc attaactatg tgattactga tgaagaacgc
    36841 aaggttaaga tggtaatggt tgacaagaat agccttgctc ttatctctgt taatgacccg
    36901 gaactcatgc tttccaaacc taaaggcctg actgctgcta ctggtatgga tgctctgact
    36961 cacgctgttg aagctttggt aacacctggt gcttatgatg taaccaagaa actgtctatt
    37021 ggtgctattg agcttatcaa ggaatatctt cctcgtgctg tagaaaatgg acatgatatt
    37081 gaagcgcgtg aaggtatggt caatgccatc ttccttggtg gtatgagctt taataatgct
    37141 ggtcttggtt atgttcactc aatggctcac caactcggtg cagtatataa tttgccacat
    37201 ggtgtttgct gtgccatgtt gctaccagtt atagaacgtg aaaatgctaa acgtgtacca
    37261 gaagctttcc gcaatgttgc caaagccttg ggacttcatg tagaaggtaa atcagatcaa
    37321 gaatgtgccg attatgcgat tgttgagatt gagaagcttt ctgagacagt aggtattcct
    37381 aagaaactga ctgaacttgg tattgaagaa aaagatttcg actttgaata cctttctaag
    37441 aatgccttga ttgatgcctg cgcaccagga aatccattta tgccaacctt agaagaaacg
    37501 attgcctttt ataaagagtt attttagcaa gagattggac gacaatagga caattcacct
    37561 ctaattattg acatttcagg aaaaatcgca gtaaaaacgg cacagccttc tttaaatgtg
    37621 ctataatact agaaaaatac ttgtggaggt tccattatgg caatattttt catgattttt
    37681 ctgattgttt gtgtgctcct attggtgata gtcacactga gtacagttta tgtggttcgt
    37741 cagcagtcgg tggcgattat tgaacgcttt gggaaatacc aaaaggttgc caatagcggt
    37801 attcatattc gcttgccttt tgggattgac tcgattgcag cacggattca gttgcgcttg
    37861 ttgcaaagtg atattgtggt tgagactaag accaaggaca atgtgttcgt tatgatgaat
    37921 gtagcgactc agtaccgtgt caacgagcag agcgtgacag atgcttacta taaactcata
    37981 cgtccagaat ctcagattaa atcttatatc gaagatgctc ttcgctcttc tgttccaaaa
    38041 ttaaccttgg atgaattgtt tgagaaaaaa gatgagattg cccttgaagt tcaacaccaa
    38101 gtagcagaag aaatgaccac ttacggctac attatcgtga aaaccttgat taccaaggtc
    38161 gaaccggatg cagaagttaa gcaatccatg aatgaaatca atgcggcgca acgtaagcgg
    38221 gtcgcagcac aagaattggc ggaagctgac aagattaaaa ttgtcactgc agctgaagcc
    38281 gaagcagaaa aagaccgcct tcatggtgtg gggattgccc aacaacgtaa ggcgattgtg
    38341 gatggattgg cagagtctat caccgaactc aaggaagcca atgttggcat gacagaagaa
    38401 caaatcatgt ctatcctctt gaccaaccag tatttggata ccttgaatac ctttgcctct
    38461 aaaggaaatc aaactatctt tttaccaaat actccaaatg gtgtggatga tatccgaaca
    38521 caaatcttgt cagcccttcg cgctgagaag aaataataga ctaatactct tcgaaaatct
    38581 cttcaaacca cgtcagcgtc gccttgccgt atagatgtta ctgacttcgt cagttctatc
    38641 tgcaacctca aaacagtgtt ttgagctgac ttcgtcagtc ttatctacta cctcaaaacg
    38701 gtgttttgag caacctgtgg ctagtttcct agtttgctct ttgattttca ttgagtacaa
    38761 agagcttggc aacaggctct ttttgtattg cgtttattaa gaaaaacaaa aaacatcgat
    38821 atacatttaa ctaaaaatta ttgtatgtta tctcccttaa ttaggaatga taagggaata
    38881 actagaaaga tttgtgaata caaactattt ctgatataca aaatatacag taataatgaa
    38941 tgatgggaga tgggatgaaa gaatttcaat ttgagagaaa gccgcgtttt tctttgaggc
    39001 catatgcaat aggagcttgt taggtcttgc taggaacgag tttatttttt gctggtatgg
    39061 gtgatcagcc tgtacaggat acagaaacga gttcagcact aattttaagt cattatttgg
    39121 atgagcagga tttatctgaa aagctgaaat ctgatttgca atggtttgaa ttagaaaaca
    39181 agcttttgaa cttatgggag tattaggtta ctatgaagca tttgttcctt atgtttcaaa
    39241 tcaatacaaa aaccaagctg aagaagaagg caaaccgcta tctgataaat atattttcga
    39301 aaaaatatta ggaaaaacat atgcagcctt caaaaaagat caaattaatg agcgtgtcga
    39361 gaaattaggt aagttaaaac ctattacaat aaattacaac ggaaaatcag aagtaattga
    39421 tagtaaagaa aaattacaag agcttatgaa taaagtcgtt aaagacgaag tggctcaaat
    39481 atagtaaaat gaaataagaa caggacaaat cgatcaggac agtcaaatcg atttctaaaa
    39541 atgttttaga agtagaggtg tactattcta gtttcaatat actataaaat caggcaatac
    39601 catggctaaa aagtttgagt ttatcgaaac accagtgcaa aaactgaaaa aagcgattta
    39661 taaagctcat ctcaaagatt cagatgactt tagaccagaa acatccacac aaatcttttt
    39721 gaaagctgtt tgaagctttg tccttgtttt cttagttcat agatctgaac tttatcttca
    39781 taactcaatt tcataataaa acaccccaaa agttagattt attctgtcta acttttgggg
    39841 tgcagttcat taatcggtcg attttttttg gtagaaacag ttgcctgatt aagttgcaag
    39901 tcgatagacg gcttcggcat aaatatccat agcacggtac aaatcttcta gaacggcaca
    39961 ttcatttgcc tgatgttctg tttgcttcgc tcctgggaat aaggcgccga aggctacaca
    40021 atttggcatg gtgcgagcaa aagtggcacc accggatgaa atagcaggac tgttatcgcc
    40081 agtcttttct tggtagattt gcatcagtgt gctaacgagt ttactgtctt ttgcgacgta
    40141 tagaggcgct agatagtcaa actcttcgta gcggagttgg tagttttgtg cacatcttgt
    40201 aagcaactct actagttctt ccttgtcagc taagacagga gtccgaatgt caatacggat
    40261 ttcagaacgt tcatgattga tcatgagacc tgcgacatta aaggataggt gaccagaagg
    40321 ttcatctgct atatcaccaa agatttgtct tcctgtgccg tcttgacctg cttgtgttgc
    40381 aagaaaactg agagcagggt gttcttggag aggagcaaga atggtagcta gtcggatgac
    40441 agcattgata ccttgactag catccttagc atgctttggc actccgagaa ccgttacggt
    40501 ttgttcagtg gattggtaat cataaccagc ttctttgaga tcgttacaaa cctgttcata
    40561 gaggggacct tggtagttgg ccttgtctgg tacaacgtta aaggcgcctc ctacttcaag
    40621 ctctagttga tccgatccag ggccatgaag tttgacctgt agaagccctt tttcagcata
    40681 ggtcagagga aaagatgagt caggtgcaaa gcccatgctg gcctgttctt cgatggtatt
    40741 gtagcgtgcc atgcagcgcc agagggtttc ctcatcggta ccaaagataa agcgtacgcg
    40801 ctttttgaac tgaatacctt ggtccagcaa gctttttact gcatagagag ctgcgagcga
    40861 agggccttta tcatcttgga caccacgtcc gaatacccag ccgtctttga tagttgcttc
    40921 aaatggcggt gtctgccaat ctgcttcatc acctgatgga acaacatcca aatgacagag
    40981 aatggccaga agctctgctc cctgaccgat ttctgcatat ccgtaataac ctttagggtc
    41041 aagataggta gtgaaaccta tgtctcgaca aatctctaaa gttttttcta ggacatcttg
    41101 gattgcttgt ccaaaaggtg ttccattttc tccttcattg agtactgaag gataggaaat
    41161 caaggttttt aatgatataa gaaattcatc tttaacttga tttgttatat ctattttcat
    41221 ggaatcacct cactcactat tttataggaa tggaaggaag gttccaagga gaagaagggc
    41281 gatggtcact acaataatag cgactacgag tttgcccatg aatttccacc aagtaccaat
    41341 gttgatacgt ccaagtgcaa gagctcccat cacaatacca gatgttggtg caatcaagtt
    41401 caagacacct gaagcagatt ggtaagcagt gataatcaag ctaggacgga catttacaaa
    41461 ttctccaagt ggagccatga tacccatagt tgcgctggca agaccagatg aagatgggat
    41521 caagaatgac ataggtagat agaagatata agttacaacg ataaagactt gtgaagatag
    41581 accgctcaag ccttctttac cccagttgag gattgtatcg gtaatcatac cgtcgttcat
    41641 gataacttga ataccacgag caatcgctac gatcaaggca acactgagca agtcagcagc
    41701 accattcatg aaggaagaga taatcttatc ttctttaaga ccataaataa caccaatcag
    41761 gatacccata aaggcaaaga gcattgcgcc ttctgggaag taccaagtac ctagtgcaga
    41821 agtagatgaa ccgacaatat taccaataac tggaagacca gtcaaccaag cattaaagtc
    41881 atcaaaaatg gtaacgccaa ggtctgtcca tggaatgaag ctcaatacca tcaagatgaa
    41941 tgtcaacaca aataagaaga gaactgattt ttgtttgctg ctaagtgtag attctacaga
    42001 tgaagattct tctacgttaa agtgtttcaa atcttctttg cgagtactat aaaccagtga
    42061 cttagtcgga tctttttgaa tcttatccgc ataacggtaa acaaaccaag tactaagagc
    42121 agtcaaggta acccagaaga tcagacgaag tacgataccg tcccctgtac caactcccgc
    42181 agtcgctgaa gcaatacctg tcgcaaatgg attcagagta gatgccaaac agccgatttg
    42241 agaaccgagc aaaataattg caacaccagt caggctatca aaaccaacgg ccatcataac
    42301 tggcacaagg agtggataga aggccattgt ttcttccccc ataccataag ttgtaccacc
    42361 gagggcaaac aaaggcatca gtaccaaaat taacattttt tcgcggccct tatacttctt
    42421 cacgatagag gcaatcccta cgtcaagagc accagttttg ttgacaatgc caaggaaacc
    42481 accaaccata aggatgaaga aggctacatc aatcgctgcg ctcgtttctt taatgagcga
    42541 accttcctct ggatgagtac ctagcatagc ccgaatcggt gccatgagga catcccaaat
    42601 cccttgtgga ttttgaggct gagcctcgta aataccttct ataaaagccc ctgcagggat
    42661 aaaccaagtt agcactgcca taatagcaat gattatcaat aatacggtgt aagatgaagg
    42721 catcttaaac ccttttttag ctttttcact catttgtttt tcctcctgat gtctaacaaa
    42781 gtgtaaaaaa ccaactactt tcttaaataa acattcaaga aaacgctttc tatttatatt
    42841 tgttttacca tattaaagtc taaaactagt atcttttgaa atattgtaca tgttttcaag
    42901 aataatttct aatttgatat aaagatacta gaaatagaat acatcttatt agtaaaacaa
    42961 cttatccttt ttcaataatt gttccgcttt cagattcaat caaggcgcct agattttcaa
    43021 gggaagtaat aactgctttt ccttctggac gaccattgac aaaagcgata gctgcttcta
    43081 cttttggaag catgctacct ggtgcaaact gatcttgttt gatatattct tccagctggg
    43141 caacattcac atgttccaat ttttcctggt ttggcttgtt gtagttaaca aatacataat
    43201 ctacacctgt caaaacgatg aagaggtctg cctcaaccaa ttctgccaaa cgttgggaag
    43261 cgaagtcttt atcaataacc gcttcgacac cagtcaaatg tccattgttt tctttgacga
    43321 cgggaatacc gccaccacct gcagctacga cgacttgacc actatttaaa agagtacgga
    43381 tggtttcaat ttctttgatg tcaacaggtt ttggtgaggc aacgacctta cgccagccac
    43441 ggccagcatc ttccttgaaa gtcgctccgc tcttttcggc ttctgctttt gcttcttctt
    43501 ctgaatagaa aggaccgatt ggtttactca aattaacaaa agctggatca tttttatcta
    43561 cgacaacttg cgttacaaca gaggcaacat ttttttcgat gccttcatcc aagagagcat
    43621 tttgcaaagc atttttcaac cagaaaccga tgctaccttc tgtcatagcg acaagtgagt
    43681 cgagtgggaa ggcagggttc ttttcagagt ctgatgccaa atgttggagc aagagattcc
    43741 caacttgagg tccattaccg tgagtgataa tcagatcatc tccattttta atcaatttta
    43801 caagatgctt agctgtttca actaaagctt cttgttgagc ctttgctgat gggtcagaag
    43861 aaagaatcgc atttcctccc aaagctacta caattttacg atttgccata aattctcctt
    43921 tatcacactc aatagaatgc gtttagattt caatttaatg atttttcaca tattttataa
    43981 gaaataatag attaccatta cataaaagag gaccggacta aagctattag tcgcagccct
    44041 catagctgtt ggtagacggt ttattatcta aaattatact ttaggaatat aaaggttacc
    44101 aagtgtagca gccataacag ctttgatagt gtgcatacgg ttttctgctt gatcgaagtg
    44161 gcgagcgtac ttgctgcgga agacttcgtc tgttacttcc atttcttcta caccaaattt
    44221 ttcagcaacg tctttaccat aaacagtgtg agtatcgtgg aatgctggca agcagtgtag
    44281 gaagatcaag ttttcattgc ctgctttttt aactaagtcc atattgactt ggtaaggttt
    44341 aagaagagct acacgttctg cgaatttgtc ttcttcaccc attgataccc aaacgtctgt
    44401 gtaaagaacg tctgcatctt taactgcttc atcagcatct tcagtgatga gaacatgtgc
    44461 gccactttct ttagcaaatc cttctgccaa ttcaacgatt tctttttctg ggaagagttc
    44521 ttttggtgag aagatgtgaa cattgacacc aaggatagca cctgttacga gcaagctgtt
    44581 ggcaacgttg ttacgtccat caccacagta taccaatgtc aagccttcca agcgaccgaa
    44641 gttttcttga acagtcaagt agtcagcgag catttgagtt gggtgccatt cgtcagttag
    44701 accgttccat actggaacgc ctgagaattc tgccaattct tcaaccatac gttggctgaa
    44761 tccgcggaat tcaatcccgt caaacatacg tcccaatact ttagcagtat cttcagtaga
    44821 ttctttttta cccaactgaa tatcatttgc tccgaggtat tctgggtgag caccaaggtc
    44881 gatagccgca gttgtaaagg ctgcacgagt acgagtagat gttttttcaa ataggagagc
    44941 gatattcttg ccagcaaggt agtggtgttg aatattgcgt tttttcaaat ctttcaagtg
    45001 agctgaaaga ccaataaggt attctaactc tgcacgggta aagtcttttt ctgctaagaa
    45061 gctgcgtcct tggaatactg aatttgtcat tttattattt cctctttcta ttttttacat
    45121 tttctattga cgaataccga acagcgatta cacttcttca cgttcaaatg gcatagacat
    45181 acaacgaggt ccaccacggc cccgaaccaa ttcacttccg cgaatcttaa tcaagcgaag
    45241 cccgtattct tccaaaatct tattggtcac ggtattgcgg tcataaacaa ctaccacacc
    45301 aggtgcgatg gtcaaagtgt tagaaccgtc gttccattgt tcacgcgcag ctgctacgat
    45361 attgccacca ccgcaacgaa tcaaatgaac tttttctaca ccaaggtttt gagcaagaag
    45421 ttcagctaag tcacctttct cttcaacgat tttaagtttt tcgttttcgt aagtaactga
    45481 gtaaacgtga aggtcgcctt cgatttctgg gtgaatagtg aacttgtcat agtctaccat
    45541 agtgaagaca gtatccaagt gcatgaattt acggttgtta gcaaattcaa aggccaaaac
    45601 tttcttgaag ccaacatttt tcttgaagat gttggcttca agaaagtttt tcgatagaag
    45661 ctgcgtctgt acgttgagag atacctactg caaggacgtc tttagaaaga actagctcgt
    45721 ctccaccttc gatacgcgta tcttcttcac ggttgtagac caaatccact tttccgccat
    45781 agattgggtg gtatttgaag atatacttac cgtagagtgt ttcacggtta cgagtgtctg
    45841 caaacatgtg gttaagcgat acggcgtttc caattgttgc aaatgggtcg cgagtgaaat
    45901 agaggtttgg catcgggtca attgcaaatg gataatcgga ttcaactaag tcagttagat
    45961 ctttagcttc gtcaggaatt tctggcaatt caactttttg aatcccagcc attgtttttt
    46021 caaccaattc ttggttgtcc ttgatgccgt gaagtaattc acgaatagca accttggttt
    46081 gacgatcacg gatgttggct tcgtctaagt attcctcgat aaattgatcg cggatttctg
    46141 gagaggtcaa tgattcagca gcgagttgtt ctaggtagag aacctcaatt ccttcatcgc
    46201 gaagagcttg ggcaaatgca tcatgttctt tttgagcatc ttccaagaaa ggaatatcat
    46261 caaaaagaag cctttcaaga tagtccggca acaagttttc taactccttg cctggacggt
    46321 gtaacataac ttttttcagt ttcccaattt ctgagaagac ctgaattgga tgtgaagaca
    46381 tgtattttcc tccttaaaaa ttttgacttg gcaccatttt gggtaccgct tacatgtatg
    46441 ttataacgca attcctaggt aatgtcaatg gctataattt ctcggaaaat aatataaatt
    46501 atgatattta gcacaatttt atgttattat acacaacata ggatgtaata catatataca
    46561 aatgcataaa cttctattaa aaaggatata aaattttttt aaaaaatttt tcaaaaaata
    46621 tacaaatgac caaaaagtgt ccaattatca tctggttatc acttggatct gtataaagag
    46681 aaatgtttgt gtgaaaggat aaaaagatgc aacattcttt tgaagataga ttttggagaa
    46741 gcatttcttg ttcaattgta caaattatag aatcttttct gagtatttag gaagagataa
    46801 ttatcttatt gaccctcttt ttattttttg ttatagtcga cgaggtgata gtttagaata
    46861 atcacttatt cacaatctgt ggaaaagtct ggagagtgaa tggtcttcac acaatgacct
    46921 gaaagaagcc tgagaataat tatggagagt agcattctga gaggtgttag cagaaccata
    46981 tgacagagtt gtttgaagag ggaatattga ggagagaaat cctgagccta ccagttggag
    47041 ttggaaagag ctggctgtta gatcatggtt tattatccac aacctgtgga taaccttgtg
    47101 aacaagagaa gttgctaaag aaggagatat ataacgatga agaaaatcaa accgcatgga
    47161 ccgttaccaa gtcagactca gctagcttat ctgggagatg aactagcagc ttttatccac
    47221 ttcggtccta atacctttta tgaccaagaa tgggggactg gacaggagga tcctgagcgc
    47281 tttaacccga gtcagttgga tgcgcgtgag tgggttcgtg tgctcaagga aacgggcttc
    47341 aaaaagttga ttttggtggt caagcaccac gatggctttg tcctttatcc gacagctcac
    47401 acagattatt cggttaaggt cagtccttgg aggagaggag agggcgactt gctccttgaa
    47461 gtatcccaag ctgccacaga gtttgatatg gatatggggg tctacctgtc accgtgggat
    47521 gcccatagtc ccctctatca tgtggaccga gaagcggact acaatgccta ttatctggct
    47581 cagttgaagg aaatcttatc aaatcctaac tatgggaatg ctggtaagtt cgctgaggtt
    47641 tggatggatg gtgccagagg agagggcgcg caaaaggtta attatgaatt tgaaaaatgg
    47701 tttgaaacca ttcgtgactt gcagggcgat tgtttgattt tttcaacaga aggcaccagt
    47761 atccactgga ttggcaatga acgagggcat gcaggtgatc cactgtggca aaagatgaat
    47821 cctgataaac taggaacaga agcagagctg aactatcttc agcacgggga tccctcgggc
    47881 acgatttttt cgatcggaga ggcagatgtt tccatccgtc caggctggtt ctaccatgag
    47941 gatcaggatc ctaagtctct cgaggagttg gtcgaaatct actttcactc agtagggcga
    48001 ggaactccac tcttgcttaa tattccgccg aatcaagctg ggctctttga tgcaaaggat
    48061 attgaacgac tttatgaatt tgcgacctat cgcaatgagc tctataaaga agatttggct
    48121 ctgggagctg aggtatctgg tccagctctt tccgcagact ttgcttgtcg ccatttgaca
    48181 gacggccttg agaccagctc ttgggcaagc gatgcagact tgcccatcca gttagaactc
    48241 gatttaggtt ctcctaaaac ttttgatgta attgagttaa gagaagattt gaagctaggg
    48301 caacgaatcg ctgcttttca tgtgcaagta gaggtggatg gtgtctggca ggaatttggc
    48361 aggggcttca cagttggtca taagcgcctc ttgcgaggtc cgctagtaga ggcacaaaag
    48421 gtgcgcgtga tgattatcga ggcacaatct attcctgtat tgaccaagat ttccctttat
    48481 aaaactcctg gattatcaaa aaaagaagtt gttcaggaac tagcatttgc agaaaaaagc
    48541 ctagctgtgg caaagggaga gactcttcat tttaggattg aacgtagtga aagtagctcc
    48601 tctttagagg ctaagatttc gattcaaccg gggacaggtg tccatggtgt cgcctatcag
    48661 gatgagattc aagtccttgc gtttcaagct ggtgagactg aaaaaaggct gacgctacca
    48721 accttgtatt tcgcaggaga taaaaccttg gatttctatc tgaacctaac ggtggatggt
    48781 cagcttgtgg atcaacttca agtccaagtt tcataaaaga agaacctttg cgcgatgcaa
    48841 aggttctttt ggttattagt gatttggtag ccagctgagg gtgaaagtta gttgttcagc
    48901 ttttaggagg tcttggtgtt gaatagttga tacgagtgtt ttgtccagtc ggcattcttt
    48961 gacaaagtta aaatggttgt ggttttgttt agtatggata tccagccatt tatcttcttt
    49021 agctaagtag actcgtagat ggtcaaagag agggattccg aggtcatagc ttggttttcc
    49081 tggacaggtt ggataaaatc cgagagctga ccagatgtac caagcagaga gactaccatt
    49141 gtcttcatct ccaggatagg cttcccaact tggctgaaaa gctttctgac ggagcgtctt
    49201 gataagaagg gcagtgtagt cagggtaatc gctgtagcgg aagagataag ggatgtggaa
    49261 actaggctgg ttggaaatgg ctatttgtcc aaaaggagca gtagccatct cgctcatttc
    49321 gtgaatttca taaccatagc ctgttgtttc aaagagggga gcatcttgac aagctttcaa
    49381 aagatagttg ctaaaggttt cttttccacc cataagttgg attaagccag ggatgtcgtg
    49441 gagaacgcct aaagtagctt gaatggcaga gcattcagcg tagtctcgcc cccaactata
    49501 aggagagaag tcagggtgaa agtttccttg attgtctcgt gctcgcatgt aacctgtctc
    49561 agcgtcaaat agctggcggt aattttgtga agcagccttg taggtttcag cgatttctat
    49621 gttctctagt tttttggcac agctagcgat acaaaagtca ctataggcat agtctagagt
    49681 atggctaaca ctttcgtggt ggtcggtaga gaggtaacct agttcttggt attgggctag
    49741 tccgtggcgg ccattgattc cgagagggtc ggctttgctg gctgtttcga gcatggcttg
    49801 gaagagttct ccttctaggt caggggccat gtccttgcag gcgctatctg cgataatacc
    49861 gtctaaaagt gtacctggca tcataccccg ttcatctgga gccagccatt ttggaaggaa
    49921 accagtatcg cggtagctat tgaggaaacc ttctaaaaag cgttgatagt gctccggtat
    49981 gataagggca aagaggggga aggtggtgcg gaaggtatcc cagaaaccat tgttgctaaa
    50041 gaggacacca ggcttgacag taccagtagc cagatccatg tggatggctt gccctgactc
    50101 atcaacctca taaaaagtct gtgggaagag gaagagtctg tagaggcagt ggtcaaagaa
    50161 ggttcggtca gcctctcctg tctctataat gtcaaaacga tggaggagat tttcccaatc
    50221 cgcttgggca cttgttttac agctatcaaa atcttcttga ggtagattga ttagagcttg
    50281 agaaggagag atgaaagaag tggctagttg catctcggtt tgactacttg ctaagtcaat
    50341 tcgccagtct ccagcttctt ggctgatagc aagaatatcc gtgttcattt gcagggcagt
    50401 gaagagcatc agtggatttt tattggtctc tgttttccct tcttgtctga gagccagagt
    50461 ccgcttatct acctgctcaa ctgttagttc atctgctgcg tgaagataga gggagagggc
    50521 tttgccttgc ttttgcttca aacgaataga agcaccatag caagtcggtg tgagctgggt
    50581 ttcaatctga tagcgtaggg agaaaatctt tagataatga ggttggaaag aggccttatc
    50641 cctatcatag gaagattggc ggtgaaagag gctgtctcca cccagttgac tggtgacagg
    50701 tgtcagaagg agccaagagt agtccccaat ccaaggactg ggctggtgag ttaatcgaat
    50761 cccctgaaag ataggcagat gcggatcgaa gaaccaagat ccatcctggt cactggtctg
    50821 gggcacaaag taattcatcc caaaaggtac gcctgtgtat ggcagggtat ttccccgaga
    50881 aaaggcatgc ttgttggtag ttccaaagcg ggtatcgatg gtttcaagta gtggtttcat
    50941 agtctttcct ttagctgttt ttctacatta tatcagaaaa agagggcctt tagaaaagga
    51001 gtttcaaaga taactatttt gtagaaaaat gtctatcatt tgtgtatgta ttttctgtct
    51061 caaaagctat atactgaaca tgaaacttgt ttgaaagagg taaaatttaa aatggtttat
    51121 tcgaaagaaa tcgtcagaga gtggctggat gaagtagcag agcgggctaa ggaccatcca
    51181 gagtgggtgg atgttttcga gcgttgctac accgatacct tggacaatac ggttgaaatc
    51241 ttagaagatg gttcaacttt tgtcttgact ggggatattc ctgccatgtg gcttcgagat
    51301 tcgacagccc aactcagacc ctaccttcat gtagctaaaa gagatgccct cctgcgtcag
    51361 accattgcag gtttggtcaa acgtcagatg accttggtac tcaaggatcc ctatgctaac
    51421 tccttcaaca ttgaggagaa ctggaaaggg caccacgaga ctgaccacac agaccttaac
    51481 ggctggatct gggagcgcaa gtatgaggtg gattcacttt gctatccttt gcagttggct
    51541 tatctcctct ggaaagagac tggcgagact agtcagtttg atgagacttt tgttgcaacg
    51601 actaaggaaa ttctccatct atggacagtt gaacaagacc acaagaactc tccttatcgt
    51661 tttgtccgag atacggaccg taaggaagac accttggtaa atgatggctt tggacctgac
    51721 tttgcagtga caggtatgac ttggtcagcc tttcgtccga gtgatgactg ttgccagtat
    51781 agttacttga ttccgtcaaa tatgtttgct gtagtagtct tgggttatgt gcaagaaatc
    51841 ttcgcagcat taaacctagc tgatagccag agtgttattg ctgataccaa gcgtcttcag
    51901 tatgaaatcc aagaaggaat cgaaaactac gcttacacca ccaacagcaa gggcgaaaag
    51961 atttacgctt ttgaagtgga tggcctagga aatgccagca tcatggatga tccaaatgta
    52021 ccaagtctac tagctgcgcc ctatctgggc tactgttcgg tcgatgatga agtgtatcaa
    52081 gctactcgtc gtaccatttt gagctctgaa aatccatact tctaccaagg agaatacgct
    52141 agcggtctag gaagttctca taccttctat cgctatatct ggccaatcgc cctttctatc
    52201 caaggattga caacaagaga taaggcagag aaaaaattct tgctggatca gctggttgcc
    52261 tgcgatggtg gtacaggtgt catgcacgaa agcttccacg tagatgatcc gaccctctac
    52321 tctcgtgaat ggttctcttg ggctaacatg atgttctgtg agttggtctt agattacttg
    52381 gatattcgct aaggggctcg ctttagctca accgattctt atcagaatca caagtttaca
    52441 tttaaaacgt taaaatttaa atttagaatg aggttttact tcatggaaaa tattgttgta
    52501 catattatct cacatagtca ctgggaccgt gagtggtact tgccttttga aagccatcgt
    52561 atgcagttgg tggaattgtt tgacaatctc tttgatctct ttgaaaatga ccctgagttc
    52621 aagagtttcc acttggatgg acaaactatt gtccttgacg actacttaca aattcgccct
    52681 gaaaatcgtg acaaggtcca acgctacatt gacgagggca aacttaaaat tggtcccttt
    52741 tacatcttgc aggatgacta cttgatctcc agtgaagcca atgtccgcaa taccttgatt
    52801 ggtcaacaag aagctgccaa atggggtaaa tcaacccaga ttggctactt tccagatacc
    52861 tttggaaata tgggacaagc gcctcaaatt cttcaaaaat caggcattca cgtggcggcc
    52921 tttggtcgtg gtgtgaagcc gattggattt gacaaccaag ttcttgaaga tgagcagttt
    52981 acatcccagt tttcagaaat gtactggcag ggtgtggatg gtagtcgtgt tttaggtatt
    53041 ctctttgcca actggtacag taatgggaat gaaatcccag ttgacaaaga tgaggccttg
    53101 accttctgga aacaaaaatt gtcagatgtg cgtgcctacg cttcgaccaa ccaatggttg
    53161 atgatgaacg gctgtgacca ccagcctgta cagaaaaatc tgagcgaagc cattcgtgtg
    53221 gcaaatgaac tcttcccgga tgtaatcttt gttcatagtt cttttgatga atatgttcaa
    53281 gctgtagaag gtgcgcttcc tgaacactta tcaactgtta caggcgagtt gaccagtcag
    53341 gaaacagatg gctggtacac acttgccaac acttcttcat cccgcattta cctaaaacaa
    53401 gccttccaag aaaatagcaa cctcctagag caagtggtag aacccttgac tattatcact
    53461 ggtggacaca accacaagga ccagttgacc tatgcttgga aaacactttt gcagaatgcg
    53521 ccacatgata gtatctgtgg ctgtagcgtg gacgaagttc accgcgagat ggaaacgcgt
    53581 tttgccaagg tcaaccaagt aggaaacttt gttaaaagta atttgctcaa cgagtggaag
    53641 ggtaaaattg ctacggataa ggctcaaagt gactatctct ttactgtcat taacacaggc
    53701 ttgcatgata aggtcgatac tgtcagcaca gtgattgatg tggcgacttg tgatttcaag
    53761 gaattgcacc caacagaagg ctacaaaaag atggctgctc ttatcttgcc aagttaccgt
    53821 gtggaggact tggatggtcg tcctgtagag gctacaatcg aagacctcgg agctaatttt
    53881 gaatacgatt taccaaaaga taagttccgc caagctcgta ttgctcgaca agtgcgtgtg
    53941 accattccag ttcacctagc gccgctttct tggacaacct tccaattgct ggaaggaaaa
    54001 caagaacacc gtgagggtat ttaccaaaac ggagtgattg atacaccatt cgtaacggtg
    54061 agtgtggatg acaacatcac agtctatgac aagacaactc acgaagccta tgaagacttt
    54121 atccgctttg aagaccgtgg ggacatcgga aacgagtata tctatttcca accaaaagga
    54181 acagagccaa tctttgcaga gcttaagggc cacgaggtct tggaaaacac agcttgctat
    54241 gctaaaatct tgctcaaaca tgaattgacc gtgcctgtca gcgcggatga aaagctagaa
    54301 gaagagcaac aaggtatcat cgagtttatg aagcgtgagg ctggacggtc agaagaattg
    54361 acaaacattc ctctggaaac tgagttgatt gtctttgttg acaatccaca aatccgcttc
    54421 aagactcgct ttactaacac tgccaaggat caccgtatcc gtctcttggt caagactcat
    54481 aacacgcgtc caagtaatga ttctgaaagt atctatgagg tggtgacacg accaaacaaa
    54541 ccagctgctt catgggaaaa tcctgaaaat cctcaacacc aacaagcttt tgtcagtctg
    54601 tatgacgatg aaaaaggggt gactgtatcc aataagggat tgaatgaata cgaaatcctt
    54661 ggggataaca ccattgccgt gaccattttg cgtgcatcag gtgagctagg tgactggggc
    54721 tacttcccaa cgccagaagc acaatgcttg cgtgagtttg aagtcgaatt tgcgattgaa
    54781 tgccaccaag cccaagaacg cttctcagcc tatcgtcgtg ccaaagcctt gcagacaccg
    54841 tttaccagcc ttcagcttgc tagacaggaa ggaagcgtgg ttgcgactgg tagcctcttg
    54901 agccattctg ttctcagcat accgcaagtt tgtccaacag cctttaaagt ggcggaaaat
    54961 gaagaaggct atgtcctccg ttactataat atgagtcaag aaaatgtgcg catatcagaa
    55021 catcagcaaa ccattcttga cttacttgag cgaccatatc cagttcattc aggactattg
    55081 gctccacaag agattcgtac agaattcatc aaaaaagaag aaatttaatt tcaaaaagta
    55141 aacatcaaaa gaaaggaggg gcgaaaaggt aagaactaac tactgattcg ccccttttta
    55201 tggtaaaaac aatgaccatt gcaacgattg atatcggagg gactgggatt aagtttgcca
    55261 gtctgactcc tgatgggaaa atactggata agacaagtat ttcaacgcct gaaaacttgg
    55321 aggatttact agcgtggcta gatcaacgct tgtcagaaca ggattacagt gggattgcta
    55381 tgagcgttcc aggtgcggtc aatcaagaga caggtgtgat tgatggcttc agtgcggtgc
    55441 cctatatcca tggcttttct tggtatgagg cgcttagctc ttatcagcta cctgtccatt
    55501 tagaaaatga tgccaactgc gttggactca gtgaactact agctcatcca gagcttgaaa
    55561 atgcagcctg tgtcgtgatt gggacaggga ttggcggagc catgattatc aatggtagac
    55621 ttcatcgagg tcgccacggt ctgggtggag aatttggcta catgacaacc cttgcccctg
    55681 ctgaaaaact taataactgg tcgcaactag catcaactgg gaatatggta cgatacgtga
    55741 ttgaaaaatc tggtcatact gattgggacg gtcgcaagat ttaccaagag gccgcagctg
    55801 gtaatgctct ttgtcaagaa gccattgagc gcatgaaccg caatctggcg caaggcttgc
    55861 tcaatatcca gtatctgatc gatccagatg tcatcagtct gggtggctct atcagtcaaa
    55921 atccagattt tatccaagat gtcaagaagg ctgttgataa ctttgtcgat acctacgaag
    55981 aatacacggt cgcaccagtt atccaggcct gcacctatca cgcagatgcc aatctctacg
    56041 gtgctcttgt caactggcta caggaggaaa agcaatggta agatttacag gacttagtcc
    56101 caaacaaacg caagctattg aggttttaaa aggtcacatt tctctaccag atgtggaagt
    56161 ggctgtcact cagtctgacc aagcctctat ctctatcgag ggtgaggaag gtcactatca
    56221 attgacctac cgcaaacctc accaacttta tcgtgcctta tccttgttgg taacagttct
    56281 agcagaagct gataaagtag agattgagga acaagcagct tacgaagatt tggcttacat
    56341 ggttgactgt tctcgaaatg cggtgctgaa tgtggcttct gccaagcaga tgattgaggt
    56401 cttggctctc atgggctact caacctttga gctttacatg gaagacactt accagattga
    56461 aggacagcct tactttggct atttccgtgg agcttattca gcagaggagt tgcaggaaat
    56521 cgaagcctat gctcaacagt ttgacatgac ctttgtacca tgcatccaga ccttggccca
    56581 cttgtcggcc tttgtcaaat ggggtgtcaa ggaagtgcag gagctccgtg atgtagagga
    56641 cattcttctc attggcgaag aaaaggttta tgacctgatt gatggcatgt ttgccacgtt
    56701 gtctaaactg aagactcgca aggtcaatat cgggatggac gaagcccact tggttggttt
    56761 gggacgctac ctgattttga acggtgttgt ggatcgtagt ctcctcatgt gccaacactt
    56821 ggagcgcgtg ctggatattg ctgacaaata tggtttccac tgccagatgt ggagtgatat
    56881 gttcttcaaa ctcatgtcag cggatggcca gtacgaccgt gatgtggaaa ttccagagga
    56941 aactcgtgtc tacctagacc gtctcaaaga ccgtgtgact ctggtttact gggattatta
    57001 tcaggatagc gaggaaaaat acaaccgtaa tttccgcaat catcacaaga ttagccatga
    57061 ccttgcattt gcagggggag cttggaagtg gattggcttt acacctcaca accattttag
    57121 ccgtctagtg gctatcgagg ctaataaagc ctgccgtgcc aatcagatta aagaagtcat
    57181 cgtaacgggt tggggagaca atggtggtga aactgcccag ttctctatcc taccaagctt
    57241 gcaaatctgg gcagaactca gctatcgcaa tgacctagat ggtttgtctg cgcacttcaa
    57301 gaccaatact ggtctaacgg ttgaggattt tatgcagatt gaccttgcca acctcttacc
    57361 agacctacca ggcaatctca gcggtatcaa tcccaaccgc tatgtttttt atcaggatat
    57421 tctttgtccg attcttgatc aacacatgac acctgaacag gacaaaccgc acttcgctca
    57481 ggctgctgag acgcttgcta acattaaaga aaaagctgga aactatgctt atctctttga
    57541 aactcaggcc cagttgaatg ctattttaag tagcaaagta gatgtgggac gacgcattcg
    57601 tcaggcctac caagcggatg ataaagaaag tttacaacaa atcgccagac aagaattacc
    57661 agaacttaga agccaaattg aagacttcca tgccctcttt agtcaccaat ggctgaaaga
    57721 aaacaaggtc tttggtttgg atacagttga catccgtatg ggcggactct tgcaacgcat
    57781 caaacgagca gaaagccgta tcgaggttta tctggctggc cagcttgacc gcatcgacga
    57841 gctggaagtt gaaatcctac catttactga cttctacgca gacaaggatt tcgcagcaac
    57901 tacagctaac cagtggcata ccattgcgac agcttcgacg atttatacga cttaatactc
    57961 ttcgaaaatc tcttcaaacc acgtcagctt cctagtttgc tctttgattt tcattgagta
    58021 taaaaacaag aacaccttgc ttggcgcagg gtgtttcgcg tgaaacagaa gaattatctg
    58081 gtttcaaatg ctacagttaa aattagtaaa acaagaaata gaagctgaaa agccagcatc
    58141 tgtagaagct tggatcattt ccgtcaaatt aaaaaggtta ctaccgacat atatagattc
    58201 caaaaacaaa aacgttagcg gaactagcag atgtgatttt atggagtttc gattttgtaa
    58261 atgctcatgc tcacgcattt ttcatggata atgttgagtg gagtcatgca gattcttact
    58321 ttcttagctt tgttagtgac gatgttgaag aacgttacac agaaaatgtc tatctggata
    58381 gcctaagtgt caaacaaaaa tttaagtttc ttttcgactt cggtgatgaa tggcgttttg
    58441 aatgccaagt actgagagaa atcgagacag aggacgaaga agcttatctc gtacgttcgg
    58501 ttggaacgtc gccagaacaa tatccagatt atgatggttt tgactatgaa gaatggtaaa
    58561 attgaaatca gtctgtgtag gcttagtatt tcaatagact tcctgcaaaa ctagaatcct
    58621 agttcatgat tgataatacc agcaatcaaa ttcattcgta atccgaagcg tttacgatga
    58681 tttcgatagg ttgttgaaaa cattttaaac gtttttactt tggcaaggat gttctcaacc
    58741 ttgcttctat ccttagatag tgcatggtta caggctttat cttcagctgt tagcggtttg
    58801 agtttgctgg ctttacgtgg agtttgtgct tgaggatata tcttcatggg cccttgataa
    58861 tcactgtcag tcaagatttt accagcttgt ccgatatttc tgcgactcat tttgaacaac
    58921 ttcatatcat gacaatagtt cacagtgata tccaaagaaa caattctccc ttgacttgtg
    58981 acaatcgctt gagccttcat agcgtggcat ttctttttac cagaatcatt cgctaattct
    59041 ttttttaggg cgattgattt atacttccgt cgcatcaata atcattatcg tgtcctcaga
    59101 gctgagagga gttcttgaaa tcgtaacacc actttgaaca agagttactt caacccattg
    59161 gctccgacgg agtaagttgc tttcgtggat accaaaatca gccgcaattt cttcataagt
    59221 tcgatattct cgcacatagt gaagagtggc cataagaagg tcttctaggc ttaatttagg
    59281 ttttcgtcca ccttttgcgt gtttaagttg ataagctgtt tttaatacag ctaacatctc
    59341 ttcaaaagtc gtgcgttgaa caccaacaag acatttaaat cgtgcatcag ttagttgttt
    59401 acttgcttca taattttgtt tcgcagggag tctattgact ctttggtagg tgtcaatgtt
    59461 tttttcatct atcccgagaa ttattttccc gccatttgta tttgcaaatg ctgagtaggt
    59521 ttcccagaaa gactctggaa gattgttttt agcttttttg tattctaaat caaccccttc
    59581 aaattttaag tccatatttt tcctttacat ctgttttttg tggttctggt atttgttcaa
    59641 gttaagtgat aatatagcga attgaatttc gagagttttt actcagttaa tttctttttt
    59701 aacccacttt aatttctttt ttaacacggg ttaaaaaaga aattaaagtg ggttaatttt
    59761 ccttgactta aaatttaaaa atgatatact gtgtttatgg agagatgaca atttataaaa
    59821 tgtactactc tattctacta gataatgatt gaataaaact ttttataaca acggctagca
    59881 aagttataat tttatatcta ttagaaaata aatatgtaag gaaatttaaa tgaaaaaaac
    59941 tacaatatta tcattaacta cagctgcggt tattttagca gcatatgtcc ctaatgaacc
    60001 aatcctagca gatactccta gttcggaagt aatcaaagag actaaagttg gaagtattat
    60061 tcaacaaaat aatatcaaat ataaggttct aactgtagaa ggtaacatag gaactgttca
    60121 agtgggtaat ggagttactc ctgtagagtt tgaagctggt caagatggaa aaccattcac
    60181 gattcctaca aaaatcacag taggtgataa agtatttacc gttactgaag tagctagtca
    60241 agcttttagt tattatccag atgaaacagg tagaattgtc tactatccta gctctattac
    60301 tatcccatca agcataaaaa aaatacaaaa aaaaggcttc catggaagta aagctaaaac
    60361 tattattttt gacaaaggca gtcagctgga gaaaattgaa gatagagctt ttgatttttc
    60421 tgaattagaa gagattgaat tgcctgcatc tctagaatat attggaacaa gtgcattttc
    60481 ttttagtcaa aaattgaaaa agctaacctt ttcctcaagt tcaaaattag aattaatatc
    60541 acatgaggct tttgctaatt tatcaaattt agagaaacta acattaccaa aatcggttaa
    60601 aacattagga agtaatctat ttagactcac tactagctta aaacatgttg atgttgaaga
    60661 aggaaatgaa tcgtttgcct cagttgatgg tgttttgttt tcaaaagata aaactcaatt
    60721 aatttattat ccaagtcaaa aaaatgacga aagttataaa acgcctaagg agacaaaaga
    60781 acttgcatca tattcgttta ataaaaattc ttacttgaaa aaactcgaat tgaatgaagg
    60841 tttagaaaaa atcggtactt ttgcatttgc ggatgcgatt aaacttgaag aaattagctt
    60901 accaaatagt ttagaaacta ttgaacgttt agccttttac ggtaatttag aattaaaaga
    60961 acttatatta ccagataatg ttaaaaattt tggtaaacac gttatgaacg gtttaccaaa
    61021 attaaaaagt ttaacaattg gtaataatat caactcattg ccgtccttct tcctaagtgg
    61081 cgtcttagat tcattaaagg aaattcatat taagaataaa agtacagagt tttctgtgaa
    61141 aaaagataca tttgcaattc ctgaaactgt taagttctat gtaacatcag aacatataaa
    61201 agatgttctt aaatcaaatt tatctactag taatgatatc attgttgaaa aagtagataa
    61261 tataaaacaa gaaactgatg tagctaaacc taaaaagaat tctaatcagg gagtagttgg
    61321 ttgggttaaa gacaaaggtt tatggtatta cttaaatgaa tcaggttcaa
//
LOCUS       DAVMAH010000003        60016 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVMAH010000003 DAVMAH010000000
VERSION     DAVMAH010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 60016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60016
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.003"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(44..997)
                     /locus_tag="VYO94_000114"
     CDS             complement(44..997)
                     /locus_tag="VYO94_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1758822.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(1065..2283)
                     /gene="sstT"
                     /locus_tag="VYO94_000115"
                     /pseudo
     CDS             complement(1065..2283)
                     /gene="sstT"
                     /locus_tag="VYO94_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            2422..2982
                     /locus_tag="VYO94_000116"
     CDS             2422..2982
                     /locus_tag="VYO94_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV1758823.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            3039..3947
                     /locus_tag="VYO94_000117"
     CDS             3039..3947
                     /locus_tag="VYO94_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1758824.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            3899..4489
                     /locus_tag="VYO94_000118"
     CDS             3899..4489
                     /locus_tag="VYO94_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV1758825.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGVGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            4492..5598
                     /gene="yqeH"
                     /locus_tag="VYO94_000119"
     CDS             4492..5598
                     /gene="yqeH"
                     /locus_tag="VYO94_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV1758826.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAYEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            5812..6123
                     /gene="yhbY"
                     /locus_tag="VYO94_000120"
     CDS             5812..6123
                     /gene="yhbY"
                     /locus_tag="VYO94_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV1758827.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            6175..6804
                     /locus_tag="VYO94_000121"
     CDS             6175..6804
                     /locus_tag="VYO94_000121"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV1758828.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRAFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            6804..7397
                     /gene="yqeK"
                     /locus_tag="VYO94_000122"
     CDS             6804..7397
                     /gene="yqeK"
                     /locus_tag="VYO94_000122"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV1758829.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            7398..7898
                     /locus_tag="VYO94_000123"
     CDS             7398..7898
                     /locus_tag="VYO94_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1758830.1"
                     /translation="MKTAFIIINVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            7911..8264
                     /gene="rsfS"
                     /locus_tag="VYO94_000124"
     CDS             7911..8264
                     /gene="rsfS"
                     /locus_tag="VYO94_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV1758831.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            8367..9113
                     /locus_tag="VYO94_000125"
     CDS             8367..9113
                     /locus_tag="VYO94_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1758832.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEAFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            9123..10220
                     /locus_tag="VYO94_000126"
     CDS             9123..10220
                     /locus_tag="VYO94_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV1758833.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILARLGIDSLAFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVVLFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            10458..10688
                     /locus_tag="VYO94_000127"
     CDS             10458..10688
                     /locus_tag="VYO94_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV1758834.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            10957..12570
                     /locus_tag="VYO94_000128"
     CDS             10957..12570
                     /locus_tag="VYO94_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV1758835.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            12700..13326
                     /gene="gmk"
                     /locus_tag="VYO94_000129"
     CDS             12700..13326
                     /gene="gmk"
                     /locus_tag="VYO94_000129"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV1758836.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            13351..13665
                     /locus_tag="VYO94_000130"
     CDS             13351..13665
                     /locus_tag="VYO94_000130"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV1758837.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            13731..16127
                     /locus_tag="VYO94_000131"
     CDS             13731..16127
                     /locus_tag="VYO94_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV1758838.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQINFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QESNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMDCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            16140..17075
                     /locus_tag="VYO94_000132"
     CDS             16140..17075
                     /locus_tag="VYO94_000132"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV1758839.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELIKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGALFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMEIASFLNGVGRTLTVGERFGD"
     gene            17068..18381
                     /gene="rsmB"
                     /locus_tag="VYO94_000133"
     CDS             17068..18381
                     /gene="rsmB"
                     /locus_tag="VYO94_000133"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV1758840.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            18396..19136
                     /locus_tag="VYO94_000134"
     CDS             18396..19136
                     /locus_tag="VYO94_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV1758841.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            19133..21112
                     /gene="pknB"
                     /locus_tag="VYO94_000135"
     CDS             19133..21112
                     /gene="pknB"
                     /locus_tag="VYO94_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV1758842.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENSSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            21227..21985
                     /locus_tag="VYO94_000136"
     CDS             21227..21985
                     /locus_tag="VYO94_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1758843.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAKPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            21987..22436
                     /locus_tag="VYO94_000137"
     CDS             21987..22436
                     /locus_tag="VYO94_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1758844.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            22498..23122
                     /locus_tag="VYO94_000138"
                     /pseudo
     CDS             22498..23122
                     /locus_tag="VYO94_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            23190..23438
                     /locus_tag="VYO94_000139"
     CDS             23190..23438
                     /locus_tag="VYO94_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758845.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            23569..24741
                     /locus_tag="VYO94_000140"
     CDS             23569..24741
                     /locus_tag="VYO94_000140"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV1758846.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            24741..26015
                     /locus_tag="VYO94_000141"
     CDS             24741..26015
                     /locus_tag="VYO94_000141"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV1758847.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(26050..27015)
                     /locus_tag="VYO94_000142"
     CDS             complement(26050..27015)
                     /locus_tag="VYO94_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1758848.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(26996..28450)
                     /locus_tag="VYO94_000143"
     CDS             complement(26996..28450)
                     /locus_tag="VYO94_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1758849.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAIQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            28826..30709
                     /locus_tag="VYO94_000144"
     CDS             28826..30709
                     /locus_tag="VYO94_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1758850.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            30858..31745
                     /locus_tag="VYO94_000145"
     CDS             30858..31745
                     /locus_tag="VYO94_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1758851.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(32065..32682)
                     /locus_tag="VYO94_000146"
     CDS             complement(32065..32682)
                     /locus_tag="VYO94_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV1758852.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(33097..33316)
                     /locus_tag="VYO94_000147"
                     /pseudo
     CDS             complement(33097..33316)
                     /locus_tag="VYO94_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(33801..33881)
                     /locus_tag="VYO94_000148"
                     /pseudo
     CDS             complement(33801..33881)
                     /locus_tag="VYO94_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            33997..34890
                     /locus_tag="VYO94_000149"
     CDS             33997..34890
                     /locus_tag="VYO94_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1758853.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            34887..36086
                     /locus_tag="VYO94_000150"
     CDS             34887..36086
                     /locus_tag="VYO94_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1758854.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMASRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(36499..37266)
                     /locus_tag="VYO94_000151"
     CDS             complement(36499..37266)
                     /locus_tag="VYO94_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758855.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(37283..37978)
                     /locus_tag="VYO94_000152"
     CDS             complement(37283..37978)
                     /locus_tag="VYO94_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1758856.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(37983..38348)
                     /locus_tag="VYO94_000153"
     CDS             complement(37983..38348)
                     /locus_tag="VYO94_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1758857.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            38488..38961
                     /gene="nrdR"
                     /locus_tag="VYO94_000154"
     CDS             38488..38961
                     /gene="nrdR"
                     /locus_tag="VYO94_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV1758858.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            38962..40131
                     /locus_tag="VYO94_000155"
     CDS             38962..40131
                     /locus_tag="VYO94_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV1758859.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     EQKAKTQKQNQTAPAKTNIPKWSNPEYKNTSSAEELEEMERQTLELLAKLDNGGD"
     gene            40132..41028
                     /gene="dnaI"
                     /locus_tag="VYO94_000156"
     CDS             40132..41028
                     /gene="dnaI"
                     /locus_tag="VYO94_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV1758860.1"
                     /translation="MESVGDVLKRQPSRFHYQDLVQKIMKDPDVAAFVQQESLNQDEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKKRLNLINFPSSLKNVSFLDVYRDDVQRLTVLKRMIEFVNDYPNNLKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSDVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            41025..41738
                     /locus_tag="VYO94_000157"
     CDS             41025..41738
                     /locus_tag="VYO94_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV1758861.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            41752..43062
                     /gene="der"
                     /locus_tag="VYO94_000158"
     CDS             41752..43062
                     /gene="der"
                     /locus_tag="VYO94_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV1758862.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            43153..43488
                     /locus_tag="VYO94_000159"
     CDS             43153..43488
                     /locus_tag="VYO94_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758863.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            43522..44313
                     /locus_tag="VYO94_000160"
     CDS             43522..44313
                     /locus_tag="VYO94_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758864.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            44306..44947
                     /locus_tag="VYO94_000161"
     CDS             44306..44947
                     /locus_tag="VYO94_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758865.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            44951..45583
                     /locus_tag="VYO94_000162"
     CDS             44951..45583
                     /locus_tag="VYO94_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1758866.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDIEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            45611..45898
                     /locus_tag="VYO94_000163"
     CDS             45611..45898
                     /locus_tag="VYO94_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758867.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFLPWGSPILGGKIDLFS
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFILFAILPILGN"
     gene            46044..48557
                     /gene="secA"
                     /locus_tag="VYO94_000164"
     CDS             46044..48557
                     /gene="secA"
                     /locus_tag="VYO94_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV1758868.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            48638..49669
                     /locus_tag="VYO94_000165"
     CDS             48638..49669
                     /locus_tag="VYO94_000165"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1758869.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            49671..50702
                     /locus_tag="VYO94_000166"
     CDS             49671..50702
                     /locus_tag="VYO94_000166"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1758870.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            50741..51109
                     /locus_tag="VYO94_000167"
     CDS             50741..51109
                     /locus_tag="VYO94_000167"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV1758871.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            51099..52202
                     /locus_tag="VYO94_000168"
     CDS             51099..52202
                     /locus_tag="VYO94_000168"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV1758872.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVV
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHIKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            52221..54236
                     /gene="recG"
                     /locus_tag="VYO94_000169"
     CDS             52221..54236
                     /gene="recG"
                     /locus_tag="VYO94_000169"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV1758873.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQTLKSENRIQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIVKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            54552..55532
                     /locus_tag="VYO94_000170"
     CDS             54552..55532
                     /locus_tag="VYO94_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV1758874.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVDDQVYNWLCGSEIPFKYLK"
     gene            complement(55886..56074)
                     /locus_tag="VYO94_000171"
     CDS             complement(55886..56074)
                     /locus_tag="VYO94_000171"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758875.1"
                     /translation="MVDKTDEVSSKHCFEVVDKTDKVSSKHRFEVADRTDEVSSKHRF
                     EVADRTDEVSNIYTARRS"
     gene            56427..56654
                     /locus_tag="VYO94_000172"
     CDS             56427..56654
                     /locus_tag="VYO94_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758876.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            56942..59839
                     /gene="nanA"
                     /locus_tag="VYO94_000173"
     CDS             56942..59839
                     /gene="nanA"
                     /locus_tag="VYO94_000173"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV1758877.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGNSNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLIFPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHKIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT        17939 a        11484 c        13690 g        16903 t
ORIGIN      
        1 aacatatata cagcaaggtg aagctgacgt agtttgaaga gtattactgt ctatattttt
       61 ggtaaaaatc aacttttact tggatgaagg ttttggcttc acgtaggagt tgaagaaggg
      121 tggcgcgggt ttcaaattct tctcttgtct tgggcagact gcggttccgg aagacttcca
      181 gataacgttc aatttcatct agcaaatcag aagcaggatt ggtctggctc agttgacctg
      241 caatttttga aaagagttgc gctaagatca ggctttcact ggcggcaagg tgacaagtgt
      301 taatctgttg ggccatgttt ctcaggatac gactttgtcg ctgtctcatc tcaaagtagt
      361 ggatatggta gtctgtctgg tgaaagaggt ggtcagagtg atccaaatag accagtctga
      421 gggcttcttt caaaagcgtg tctaattctg ctaccagctg tgctcggttg cgtccgtctc
      481 ctctggataa atagtatttg aagcgctgga ggatatcttt taacttttct tccaccagcg
      541 tgtggtagtg ctggatttcc tcttctcgtg aaggcatata gagattaaca agcaaggcaa
      601 atcctgtacc aatagcaaag agaaggaatt cgttgactaa gaggtctgga gaggttgact
      661 cttgaaccaa gagatggcta accaaaaccg tgcttggtgt gatgccaatt tcccagccca
      721 tcttgtaggc taaaggaacg tagaaggcca gatagaggcc gagactccag atatgaaatc
      781 cgctcaagtg aaaagctaga acaccgatag ccagagctag aagcatagaa aaaagacgat
      841 tgcgagccag ttttaaagta cttctacgcg tatcagatag gctcaagaga gcgataattc
      901 cagccgaaac tgctgacgaa agattgagaa aataagcaag caggcaggca agacaggtag
      961 ctaagatgag cttggtcgta cgttggctaa tagacataag aatttcctaa taagttagaa
     1021 taaaagcgta aaagacaaga catgagcagg cttgccttga tgagttattt tttacgggtt
     1081 gctgcgtatt cggcaacggc ggtaaagagg acatctgtag aagagttaag ggctgtttca
     1141 catgagtctt ggatgacacc aatcacaaaa ccaaccccaa caacttgtat ggcaatatcg
     1201 ttagaaatac cgaaaaggct acaagcaact gggataagaa ggagggaatc tccggcaata
     1261 cctgaagcac cacaggctga gatagctgct accacactga ggacaaaggc tgtggcaaag
     1321 tcaacaggaa ttccaagagt gttaactgta acaagggtca aaacgttaat ggtaatcgct
     1381 actccagcca tattgatagt agaaccgagt gggatagaaa cagaataggt atctgggttg
     1441 agtccaaggt catggcagag tttcatgttg acaggaatgt tagtcgcaga actacgagtg
     1501 aaaaaggctg tcacaccgct gacacggagg cagttccaaa ctagagggta aggattgcgt
     1561 ctcataaaga agaaggcaat caaagggttg accacagggg caacaaaaag catagtcgtt
     1621 actaatggaa ccaataaaat accatagttg gcaaggcttc cgactccctt gtcagaaatg
     1681 gttttaaaaa caagaccaag gattccaaat ggagccagat tgatgatcca ttcgacaatt
     1741 ttagaagtca cgtcagcgat agtttttagc aattctttac tatttttact ggttttactg
     1801 gcttctctca tagcgattcc aaaaatgact gcccaagata agattccaat atagttagca
     1861 gtaagcaggg cgttgactgg gctgtcaacc agtttgagca agaggttgct gaggacctgc
     1921 ccaatcccat ctggtggtgc aatttcagta ttggcactat ttagggtaat ttcaataggg
     1981 acgatgaaac ttgctagtac agctacaaga gcagcggcga aagtccctat cataggatat
     2041 acaagaaaac aacagttttc atattgctat cttgtccctt ttgatgttgg gaaagggcat
     2101 tggcaacgag ggcaaagact aggataggag caacagcttt tagacctcca acgaataaat
     2161 ccccaagtag cccaatccct gagagattag gaagggtcag tcctaggatt ccccacaaag
     2221 cataccaatc aagatacgct tgacaaggct tgccttattc caagcatgaa tgattctttt
     2281 cataataatc tcctttttgt gtagtgatta tgattatagt ataaatgata gacaaaatca
     2341 agaattttct gtctattttt tgaatattta tggagaatga gactgatgaa aatatggtat
     2401 aatgaaataa aggagtttta tatgcaaaaa tttattcagg cttatattga aaagctagat
     2461 gtgacaacca ttatcgagaa tattctaacc aaggtcattt ctcttttact gcttttgatt
     2521 gtattttata ttgctaaaaa aatgcttcat accatggtgc agagaattgt caaaccttct
     2581 ctaaaaatgt ctcgtcatga tgtcggacgc caaaaaacca tctcacgttt actagaaaat
     2641 gtgtttaatt atacgctata tttcttttta ctctactgca ttttgtcgat tttaggtttg
     2701 ccagtttcta gtttgctggc tggagctggt attgctgggg tagcgattgg tatgggagcc
     2761 caaggctttc tgtctgatgt catcaatggc tttttcattc tctttgaacg tcaactggat
     2821 gtgggagatg aggtcgttct gacaaatgga ccgattactg tatcgggtaa ggttgtcagt
     2881 gtgggaattc gtacgacaca gcttcgtagc gaggagcaag cccttcattt tgtccctaac
     2941 cgaaatatca cagttgttag caatttctca cgcacagact agacctgtta ttttaagtaa
     3001 tttgtggtac aatagaggga gtttaataag gagaaaagat ggttttagaa aagcagttgg
     3061 gcaatggttg tacctggata gacctagacc taggaaagtt gaataaacta gaagaccttt
     3121 ctgaaattta cggtttggac aaggaaacca ttgaatacgc actggataga aacgagcgcg
     3181 cccacatgga ctaccaccgt gaaagtggga cggttacctt tatctataat gtcctagacg
     3241 taaaaaagga caaggcctac tatgagactt ttcccatgac ctttatcgtc gagcatcgtc
     3301 gcctgattac cattagtaat accaagaacg cctatgtcat tgaacagatg actcgttatc
     3361 tggagagcca tgacacgctt tcgatttata agtttctctt tgccagtctg gaaatcatca
     3421 gcaatgccta ctatcctgtc attgagcaga tggacaagag tagggatgag gtcaatgacc
     3481 tcttgcgcca gcgaactacc aagaaaaacc tctttgccct gtctgatttg gagactggta
     3541 tggtttatct aacggcagct gccaaacaaa atcggatttt gttagagcat attcaaggtc
     3601 atgccttgta tcgtagtttt gatgagattg agagagaaca gtttgatgat gccatgattg
     3661 aggctcatca gctggtatcc atgacagacc taatctctca gattttacag cagctttcag
     3721 cctcttacaa caatattcta aacaataatc tgaatgacaa tttgacaacc ttgactatca
     3781 tttcagtctt gctagctgtt ttggcagtcg tgacaggctt tttcggaatg aatgttccct
     3841 tacctttaac agatgagccc catgcttggc tctatatcag tttggctagt gcaggtttgt
     3901 ggattgtttt atccttgtta ctaaggaaaa ttgcgaaaaa aagttaagaa aaggagccag
     3961 aatggcgatt gaaaattata taccagattt tgctgtggaa gcagtctatg atctgacagt
     4021 cccaagcctg caggcgcagg gaatcaaggc tgttttggtc gatttggata ataccctcat
     4081 tgcttggaac aaccctgatg gaacgccaga gatgaagcaa tggctacatg accttcggga
     4141 cgcgggtgtt ggcattatcg tagtgtcaaa taacaccaaa aaacgcgttc aacgagcagt
     4201 tgagaaattt gggattgatt acgtttactg ggccttgaag cccttcacat ttggtattga
     4261 ccgtgccatg aaggaattcc actatgacaa aaaggaagtg gtcatggttg gcgaccagct
     4321 catgacagat atacgagcag cccaccgtgc agggattcgg tcaattttgg tcaaaccctt
     4381 ggtccaacat gactcaatca aaacgcagat taaccgaact cgtgagcgtc gtgttatgag
     4441 aaaaatcact gaaaagtacg gaccgattac atataaaaaa ggaatttaac tatggaagaa
     4501 attctctgta ttggttgtgg agcaaccatt cagacgacag ataaagctgg tcttggtttt
     4561 accccccagt cggcacttga aaaaggtttg gagactggcg aagtctattg ccaacgctgt
     4621 ttccgtctcc gccactacaa tgaaatcaca gatgtccagt tgacgaacga tgatttcctc
     4681 aagctcttgc acgaggtggg agacagtgat gctttagtgg tcaatgtcat tgatatcttt
     4741 gattttaatg gatctgtcat cccaggttta ccacgtttcg tctcgggcaa tgatgtcctc
     4801 ttggtaggaa ataaaaaaga tatccttcct aagtcagtta agtctggtaa gattagccag
     4861 tggctcatga aacgtgccta tgaagaaggt cttcgtccag tcgatgtggt cctaacttca
     4921 gcacaaaata aacatgccat taaggaagtc attgacaaga ttgaacacta ccgtaagggc
     4981 cgcgatgtct atgtggtcgg tgtgaccaac gttggaaaat caactctaat caatgctatt
     5041 atccaagaaa tcacgggtga tcagaatgtc atcactactt cacgcttccc agggacaacc
     5101 ttggacaaaa tagagattcc gcttgacgac ggatcttata tttacgatac gccgggaatt
     5161 atccaccgcc accagatggc tcactacttg acggccaaaa acctcaagta tgtcagtcct
     5221 aaaaaggaaa tcaagcctaa gacctatcag cttaatcctg agcaaaccct atttttaggt
     5281 ggtttgggac gctttgactt tatagcagga gaaaagcaag gatttactgc tttctttgat
     5341 aatgaactca aactccatcg tagcaagctt gaaggagcta gtgctttcta cgataagcac
     5401 ctgggaactc ttctgacacc accaaatagc aaggaaaaag aagatttccc aaggctagtc
     5461 cagcatgtct ttaccattaa agataagaca gacctagtca tctcaggcct aggctggatt
     5521 cgtgtaacag gcatagcaaa agtcgccgtc tgggcaccag agggcgtcgc cgtcgtcaca
     5581 cgaaaagcaa ttatttaaaa caaaatcgct gagcgaacaa agtgagctca tatagcgata
     5641 gttattgccg tggtgtgatt gccaatctgt agattggcaa ggggcacaat tgagaccaag
     5701 gctcaattgt gaggtcagga aatccatttt tcaaagatga aatctttgga aaattagttc
     5761 cgaccgtccc tcaccaccta aaataactat caaaaaacaa ggaagaaaat tatgtcatta
     5821 acatcaaaac aacgtgcctt cctcaacagc caggcacaca ccctcaaacc tatcatccaa
     5881 atcgggaaaa atggactcaa cgaccaaatc aaaaccagcg tccgtcaagc tcttgatgcg
     5941 cgtgaattaa tcaaggttac tctcttacaa aacacagatg aaaacatcca cgaagtagct
     6001 gaaattttgg aagaagaaat cggtgtggat acagtccaaa aaataggacg catcttgatt
     6061 ttgtttaaac aatctagcaa gaaagaaaat cgcaagattt ctaagaaagt caaagaaatc
     6121 taagaccgaa actccaaata actgttttta tagagaaata aaggggacta gcctatgaca
     6181 atcgaactat tgactccctt taccaaggta gagttggagc cagaaatcaa ggagaaaaaa
     6241 cgcaaacaag ttgggatttt aggggggaat tttaaccctg ttcacaatgc ccatctcatt
     6301 gttgcggatc aagtacggca acagttggga ctggatcaag ttcttctcat gcctgaatac
     6361 caacctcctc acgttgataa aaaggaaacc atccctgaac accatcgtct caagatgctt
     6421 gagttggcaa ttgagggaat tgacggccta gtcattgaaa ccattgagtt ggagcgcaag
     6481 ggtatttcct acacctacga caccatgaag attttgacag agaagaatcc agatacggat
     6541 tattacttta tcatcggtgc cgacatggtt gactatctgc ctaagtggta ccgaattgat
     6601 gaactggttg acatggttca gtttgtgggg gttcagcgtc cacgctacaa ggcagggact
     6661 tcctatccag ttatctgggt ggacgtaccg ctcatggata tctcgtccag catggtgcgt
     6721 gccttccttg cccaaggtcg gaaacccaac tttctcctac ctcagccagt gctagactac
     6781 atcgagaagg aggggctcta ctgatgtcct atcaagacta tatcaactgc tcccgtgagg
     6841 ccttgttgga aaaaatggca gagcttctac ctgagaaacg tctaacccat tgtctaggtg
     6901 tggagcgtgc cgctatggaa ttagctcagc gctttggtgt agatgttgag aaagcaagtc
     6961 tagcaggtct tcttcatgac tatgctaaaa agttgtcaga tcaggaattt ctagacttga
     7021 ttgaccgtta ccagctagac cctgacctca aaaactgggg caataatgtc tggcatggta
     7081 tggtcggaat ttacaaaatt caggaagatt tggatttgca tgattcagaa atcctgcgag
     7141 ccattgaagt ccatacagtc ggtgctggtc aaatgacaga cctagataag gtcatctacg
     7201 tcgcagacta tatcgagcac aatcgagcct ttcctggagt agatgtggcg cgtgagattg
     7261 caagtctatc gctcaataag gcggtggcct acgaaacagc tcgtaccgtg gagtatctag
     7321 ctcatcaggg attccccatc tatccccaaa cccttgaaac ctataacgcc tttgtgcact
     7381 atttgaaaga gaactaaatg aagacggctt ttataatcat taatgttcag aatgttttag
     7441 tagaaactgg attccagaca aaaagtctat tgggaaaaat ttcttattta caaaaccagg
     7501 ctagaagcaa gaatattgaa attatctatg ttcaacatat tgagaactct gaagctcaaa
     7561 catcagaaga ttggcagtta tctgcgcttt taaatcgaaa acctgctgaa aaggtctttc
     7621 agaagaaata taacagtatt ttcaaagaaa ctggcttaaa agaatacttg gataagcagg
     7681 ggattgaaaa attagtttta tgtggtatgc agacagaata ttgtgtggat acctctgtca
     7741 aggttgcctt tgaatatggc tatcagctta ttgttccaga aggtgctgtc acaacctttg
     7801 atggggatga cattccagca gaaacgatta atgaatttta tgaggacatt tgggaggagc
     7861 gctttgcaga tgtcctagat tacaaacata ttttctaaaa agaggattaa atgaacgaaa
     7921 aagaattact agaactagtc gtgaaagcgg ctgatgagaa acgtgcggag gatatcctcg
     7981 cacttgatgt acaagatttg actagtgtga cggactactt tgtcatcact agctcaatga
     8041 atagccgtca gttggacgct atcgcagcta atatccgtga aaaagtagct caagcaggct
     8101 ttaaaggtag ccatgtcgaa ggcgatgcag ctggaggctg ggtcttactg gacctcggtg
     8161 ctgttgtcgt gcatatcttt tcagaagaaa tgcgtgccca ttataaccta gagaagctat
     8221 ggcatgaggc gaattcagta gatatttcag aagctcttgc ttagaagatg aactcagttg
     8281 tagtcaactg ggtttctttg cttattttag aaaaattgat agaaaggtaa agggctagtg
     8341 gtgtttacca tggagctctt agtatcatga ttatggcgac ttatgaaacc tttgcggcgg
     8401 tctatgatgc ggtcatggac gatagtttat acgacaaatg gacgaatttt tctctgcgtc
     8461 atttgcctaa gaccaaggag agaaagaaac tcttggaatt ggcttgtggg acaggaattc
     8521 aatcagtgcg cttctctcag gctggttttg atgtgactgg acttgacttg agtgcggata
     8581 tgttgaagat tgcggagaag agagcaactt cagccaagca aaagattgct tttatagaag
     8641 gtaatatgct gaatttgtcc aaggcaggga aatacgattt tgtcacgtgt tattcggact
     8701 ctatctgcta tatgcaggat gaggtggaag taggggacgt ctttaaggac gtgtacaatg
     8761 cgctgaatga agagggagtt ttcatctttg acgtgcactc gacctaccag acagatgaag
     8821 cattccctgg ctattcctac catgaaaatg cggaagattt tgccatgctt tgggatacat
     8881 atgaggacga agttcctcac tccattgtgc atgagctgac tttctttatc aaggaggctg
     8941 acggttcctt tagtcgccac gatgaagtac atgaggagag gacctatgag atcttgacct
     9001 atgatatctt gctggaacag gctggattta agtccttcaa actctatgca gactttgagg
     9061 ataaggagcc aacagaaact agcacccgtt ggttttttgt ggcgcagaag taggagaaca
     9121 tcatgaccat cacaggtatt atcgcggagt tcaatccttt tcataatggc cataaatacc
     9181 tgctggatca ggcagaggga ctgaaaattg ttgccatgtc agggaatttc atgcagcgtg
     9241 gagagcctgc tattgtggat aagtggacaa gggcccagat ggcgctggaa aatggcgcag
     9301 acttggtagt ggaattgccc tttttagtca gtgttcaggc ggcagatttt ttcggtcaag
     9361 gggccgtgga tatcttagct cggttgggca tagatagcct cgcttttggg acagaagaag
     9421 ttctagatta tcaaaaaatc gctgacttat acacagagaa aggtgctgag atggagaaat
     9481 ttgtgaaaaa tctgcctgat tccctttcct atccccagaa aacccaagct atgtggaagg
     9541 aatttgctgg tcttgatttt tcaggtaata cccccaatca tgttcttgct ctggcctatg
     9601 ccaaggcggt tgcaggacgg aatatcaagc tgcatccgat tcagcgtcag ggggcaggtt
     9661 accattctgt gaataaagat gtggactttg cctcggcgac agccctccgt caacatcaga
     9721 aggaccaaga tttcttagaa cgttttatgc cttctgttgt cctatttgag caggccagta
     9781 aggtgatctg ggaagactat tttcccttgc tccgctatca aatcttgtca aatcccgacc
     9841 taaccaccat ctatcaggtc aatcaagaaa tggctgtgcg cattaaagaa gctattaaaa
     9901 cagcccagtc tgtagaagaa ttggtcgagt tagtgactac caaacgttac accaaggcgc
     9961 gtgtcagacg cctattgacc tatattttga tgcaggctag agaaagtgac ttgccagaag
    10021 ccattcatgt ccttggattt actgaaaaag gtaggcaaca tctcaagtct ttgaaaggtc
    10081 aggtcagtct agtcagccga attggcaaag aaccttggga tgctatgact caaaaggttg
    10141 accagattta ccaactagga aagccaagta tagcagagca aaattttggc agagtgccga
    10201 ttagaataga aacaaactaa gtctactgaa aggtaggctt tttgagattt tttacgaata
    10261 atactcttcg aaaatcaaat tcaaatcgcg tcaacgtcgc cttgccgtac tcaagtacag
    10321 cctgcggcta gtttcctagt ttgctctttg attttcattg agtataaata gatagaaaag
    10381 aaaatcttgt acaagttcct gacaatttct ttcttttcgt gtataatagt ggaaaagagc
    10441 taaaacgagg tatggttatg gaagcagtcc tttactcaac attccgaaat catttaaagg
    10501 actacatgaa gaaggtaaat gatgaatttg agcctttgac ggtggtcaat aaaaatccag
    10561 atgaggacat tgtagttctt tcaaagagcg aatgggacag tattcaggaa accctgagaa
    10621 tcgcccaaaa taaggagtta tcagacaagg ttttgcgagg aatggataaa attcgcgcag
    10681 gacactagtc tcatttacag agaatacctg agtgaaatct tgctgttgtt agaaacaaac
    10741 ttcttgtatt gcataatcat tactaagtct actgcaaagt aggctttttc tcaagtctct
    10801 actaaactac tatttctaaa caacaagttt attttggtaa atgtgttcca aattccccaa
    10861 aacatattct attttaggtt tgtgaaaatc acttttttat ggtagaatgt aaaagaatgt
    10921 atgtcattcg gaataacaat aaaatgaggt aaaaacatgg aaatcatgtc gcttgcgatt
    10981 gctgtttttg ccgtcatcat tggtttagtc attggatatg tcagcatctc agctaagatg
    11041 aaatcatctc aggaagctgc agagttgatg cttttaaatg ctgaacaaga agcaactaat
    11101 ttacgtggac aagctgagcg tgaagcggat ttacttgtta atgaagccaa acgtgaaagc
    11161 aagtctctta aaaaagaagc actattggag gccaaagaag aagccagaaa ataccgtgaa
    11221 gaagtggacg ctgaattcaa atcagaacgt caagaactca aacaaatcga aagtcgtttg
    11281 acagagagag ctactagcct tgaccgtaag gacgacaatt tgacgagtaa agaacaaaca
    11341 cttgaacaaa aagaacaaag tatttctgat agagcgaaaa accttgatgc gcgtgaagag
    11401 caattagagg aagtcgaaag acaaaaagaa gcagaactag agcgtattgg tgctctgtct
    11461 caggcagaag cacgagatat tatcttggct cagacagagg aaaacttgac cagggagatt
    11521 gccagtcgca ttcgcgaagc tgagcaagag gtcaaggaac gttctgacaa aatggccaag
    11581 gacatcttgg ttcaagctat gcaacgtatc gctggtgaat atgtagcgga gtcaacaaac
    11641 tcaacggttc atctgccaga cgatactatg aagggacgca ttattggtcg tgaaggtcgt
    11701 aacattcgta cctttgaaag tttgacaggg gtcgatgtga ttatcgacga tacaccagaa
    11761 gtggtgacct tgtcaggatt tgatccgatt cgtcgtgaga ttgcccgtat gactatggaa
    11821 atgttgctca aagatggtcg tatacatcca gctcgtatcg aagagttggt tgagaaaaac
    11881 cgtcaagaga ttgacaataa gattcgtgaa tacggtgagg ctgctgccta tgaaattggt
    11941 gcgccaaacc ttcatccaga cttgatgaag attatgggac gtttgcagtt ccgtacttca
    12001 tatggacaaa atgttttgcg ccattcgatt gaggttgcta agttggctgg tatcatggcg
    12061 agcgaacttg gtgaaaatgc ggctcttgcc cgtcgtgctg gattccttca cgatatcggg
    12121 aaagccattg accatgaggt tgaaggtagc cacgttgaaa tcggtatgga attggcccgt
    12181 aagtacaagg aacccccagt tgtggtgaat acgattgcta gtcaccacgg agatgttgaa
    12241 gctgagagcg tgatagcagt tatcgtcgct gcagcagatg ccttgagcgc agcccgtcca
    12301 ggtgctcgta gtgagtctct tgaaagctac atcaagcgtc tccatgattt ggaagaaatt
    12361 gctaacggct ttgaaggagt gcaaactagc tttgcccttc aagcaggacg tgaaattcgt
    12421 atcatggtca atccaggaaa aatcaaggac gacaaagtca caatcttggc tcacaaagtt
    12481 cgtaagaaaa ttgaaaacaa tctcgattat ccaggaaata tcaaggtaac cgtgattcgc
    12541 gagcttcgtg cagtagatta tgctaaataa ataagaaaga gcagttgaaa aattactgct
    12601 tttttgttac actagataga aagactgtaa aggataatct ggctttttgc cattattcta
    12661 gagaaatgtt atttcacaga ttgactaaaa ggagacacaa tggcagaccg aggcttacta
    12721 atcgtttttt ctggtccttc aggggttgga aaaggaacgg ttagaagaga gatttttgag
    12781 agttctgaaa accaatttca atactctgta tcgatgacga cacgcgcaca acgtcctgga
    12841 gaagtggacg gtgttgacta tttcttccgt actcgtgaag aatttgaaga gctgattcgt
    12901 caaggacaga tgttggaata cgcagaatat gtcggtaact actatggaac tcctctgacc
    12961 tatgtcaatg aaaccttgga caagggaatc gatgttttcc ttgaaattga agttcagggt
    13021 gctcttcagg tcaagaaaaa ggttccagat gctgtcttta tcttcctgac accaccagat
    13081 ttggatgaat tgcaagatcg cttggtaggt cgtggaacag atagtgcaga agtgattgcc
    13141 caacgaatcg aaaaggccaa ggaagaaatt gccctcatgc gtgagtatga ttatgcgatt
    13201 gtcaacgatc aggtgcccct agctgctgaa cgtgtcaaat gtgtgattga agcagaacac
    13261 ttctgtgtgg atcgtgtcat tggtcactat caggagatgt taccaaaatc tccaactacc
    13321 cgataaaatt tagaaaatag gtacaagcaa atgatgttaa aaccctctat tgataccttg
    13381 ctcgacaagg ttccttcaaa atattcactc gtaatcttgg aagcaaaacg tgcccacgaa
    13441 ttggaagcag gtgccccagc aactcaaggt ttcaagtctg aaaaatcaac tcttcgcgct
    13501 ttagaagaaa tcgaatcagg aaacgttaca attcacccag atccagaagg aaaacgtgaa
    13561 gcagtgcgtc gccgtatcga agaagaaaaa cgccgcaaag aagaagaaga aaagaaaatc
    13621 aaagagcaaa ttgctaaaga aaaagaagat ggtgaaaaaa tttaaggttg gggggactca
    13681 atcttatttt ttctattgca agaatgtact gacaaggagg aggtgagaag atggccctag
    13741 ctaagattat cgtagatgtg cccttgatgc agacggacca gccctatagt tacaggattc
    13801 cggaggaatt tgagggaatg ctggaagttg ggatgcgggt tcatgtgcct tttggtaagg
    13861 ggaatcgcct gattcaaggg attgttcttg gtttggagtc ccaatcagat ggagaagaga
    13921 tggagcaaga tttaaaagat attgcagagg tgctggattt ttctcctgtt ctcacgccag
    13981 aacaactctg gctggctgag gagttacgca aatctgtctt ctcctacaaa atttctatcc
    14041 tcaaggccat gcttccagga tttctgaatt ctagctatga caagattctc tatcctctgg
    14101 aaggcttgag tcaggaagaa cgagtgcgcc tgtttggttc agaagattcg ctagcctttt
    14161 cttcactaga ccttgccaag caagctgaaa tgatgcgttt gactagaaaa ggcctgcttg
    14221 gtctggaata tcaggcagtc gatcaaaaga aggtcaagac ccagtcttgg tatgaggttg
    14281 accatgctca attagaaggt gttgagattt ctacacgtgc caagaaaaag ttggaactga
    14341 gagattatct gctgtctcat ccagagagcg cttccttggc tagcttgtta gagtcctact
    14401 cgcgagagca aatcaacttc tttgtggatc aaggtgctgt taccatagtc caaaaggaag
    14461 ttcaacgctc ggctgcttat tttgaaggaa ttgaagcaag tagacctttg gagttaaatc
    14521 cagaacaaag acaggcgcgt gatgcggttg tgagttctat tggcagttct caacctccct
    14581 ttctacttca agggattaca ggaagtggga agaccgaggt ttacttgcag attatccaag
    14641 gtgccctgga taagggcaag acagctattt tgctggtacc tgagatttcc ttgactcctc
    14701 aaatgaccga gcgttttata gcacgctttg gggacaaggt agccattctt cactcaggat
    14761 tatccaatgg tgaaaagtat gatgaatggc gcaaggtgga gcgtggcgat gcccaagttg
    14821 ttgttggtgc cagatctgct atctttgctc ctctgaaaaa tctgggtgtc atgattattg
    14881 atgaagagca tgaagcggct tataagcagg aaagcaatcc ccgttaccat gccagagagg
    14941 tagctatttt acgggctcag tataatcaag caactctggt acttggatct gcaacgccga
    15001 gcttagagag ccgggcgcgt gctggcaaag gcgtctatca acacttacgt ctaacccaac
    15061 gtgccaatcc tttggctaca atccctgagg ttcaagtgat tgactttcga gactatatcg
    15121 gacaaaatga gacgtcaaac tttacgcctc ctttgctaga ggctatccaa gaccgtctgg
    15181 ttaaaaaaga gcaggtggtt ctcatgctca atcgccgtgg ttattctagc tttgtcatgt
    15241 gtcgggagtg tgggacggtg gatacttgtc ccaactgcga tatttctctg accttgcata
    15301 tggataccaa gactatggac tgccattatt gtggtttctc gaaggatatt cctcaggtct
    15361 gtcctaactg taagagccac agtattcgtt actatgggac gggaactcag aaggcttatg
    15421 atgagctagc agaactcttt ccccaagctc gcattctgag gatggatgtg gatacgactc
    15481 gaaagaaagg cagtcaccaa gccttgcttg accagtttgg gcgaggggaa gcggatattt
    15541 tacttggtac tcagatgatt gcaaagggtt tggattttcc caatgttacc ctagtcggag
    15601 ttctaaatgc ggatacggcc ttgaatctgc ctgatttccg ttcttctgag agaaccttcc
    15661 agctcttgac tcaggtggca ggtcgagcag gtcgggctga aaaggcaggt caagtcttga
    15721 tacagtccta caatccgcag cactatgcta ttcgatttgc caaggatcaa gattacgaag
    15781 gcttttatgc ctatgaaatg ggaatcagac gacaactcgg ctatccacct tactatttca
    15841 cgattggtat taccctttct cacaagaaag aagaagaggt tttcaaacgt gcctatgaag
    15901 tcatgaacat tttgcggtca ggcttgtcag agaccagtcc cattctgggg ccaacgccaa
    15961 aaccgattgc ccgtacccac aacctctatc attaccagat tttaattaaa taccgtttag
    16021 aagatgagct ggggccgacc ctcaaccagg tcttggcctt gactcaagaa cgggaaaata
    16081 gtgagctccg tctcagcatt gaccatgagc cgcagcaatt tttataaaaa ggagaagata
    16141 tgacaaaact aatctttatg gggacccccg acttttcagc aacagtctta aaaggacttt
    16201 tgacagatga ccgttacgaa attctagccg ttgtgaccca gccagaccgt gctgttggtc
    16261 gtaaaaaagt tatccaagaa accccagtca agcaggctgc caaggaagca ggactatcta
    16321 tctaccaacc tgaaaaatta tctggaagtc cagagatgga agaacttata aagctaggag
    16381 cagatggaat tgtgactgct gcttttgggc agtttctccc aagcaaactc cttgatagca
    16441 tggactttgc tgtcaacgtt catgcctccc tccttcctag acaccgtggt ggtgcgccta
    16501 tccattatgc cttgattcaa ggggatgagg aagctggtgt gaccatcatg gaaatggtta
    16561 aggaaatgga tgcaggagat atgatttctc gtcgcagcat tccgatcaca gatgaggaca
    16621 atgttggcgc cttgtttgaa aaattggcgc tagttggtcg tgatttgctt ttggacactc
    16681 tgcctgccta tattgctggt gatatcaaac ctgaaccgca ggatacgagt caggttacct
    16741 tctctccaaa tataaagcca gaggaagaaa aactggactg gaacaaaacc aatcgtcaac
    16801 tctttaacca aattcgtgga atgaacccct ggcctgttgc ccatactttc cttaagggcg
    16861 accgctttaa gatttatgaa gccctaccag tagaaggtca gggaaatcca ggtgagattc
    16921 tctctatcgg caagaaagaa ttgattgtcg caacggctga aggggctcta tccctcaaac
    16981 aagtgcagcc agctggtaag cctaagatgg agattgcttc cttcctcaac ggagttggac
    17041 gtacattgac tgtaggagaa cgatttggtg actaaagtag aaacggctag aagtttagct
    17101 ctagcagtgc tagaggatgt ttttgtgaac caagcatatt caaatatcgc cttaaataag
    17161 catctaaagg gaagtcaact tttggcagca gacaagggct tagtgaccga gctggtctat
    17221 ggaacggtag cccgtaaact gactctggaa tggtacctat cccactttat cgaagacaga
    17281 gaccagttag acagctggct ctatgtcctt cttctcatga gtgcctacca actccgctat
    17341 ttggacaaga ttccagatca tgctgtggtt aatgaagcag tggaattggc caaactccgt
    17401 aaaaaaggca gtgaaaaatt ggtcaacgct gtccttcgcc gtatcttgcg tgaaggctgg
    17461 ccagatattg ctagcatcaa gcgaaaaaac aagcgtgact ccattgccta ttctctccca
    17521 gtttggctag ttgccaaact caaggaagaa tacggagagg agagagcaaa agccatcttt
    17581 gaaagcctgt tagtgcgaaa caaagccagt attcgtgtaa cagacctaag tcgaaaagag
    17641 gaaatccaag ccttgttgga ggcgaatgat tcccttttag caaccactgg tctggttaag
    17701 gagcaggggc attttgcagg gcataatttg tttgcggatg gagccattac catccaagac
    17761 gagtccagtc agctggttgc tccgacgctt gatttacaag gtgatgagcg agtgcttgat
    17821 gcctgtgcgg ctccaggtgg gaaaacagcc catatagcct cttatcttac gacaggtcag
    17881 gttactgctc tggacttgta cgaccacaag ttggatttaa ttcaagaaaa tgcccaacgt
    17941 ctgggagttg cagatcgggt tcaaactcaa aaattggatg ccagaaaggt gcatgagttt
    18001 tttgaccagg attcctttga taagattttg gtggatgctc cttgttcagg aatcggtctt
    18061 ttgcgccgaa aaccagatat caaatacaat aaagaaacgg cagatttcgc gtccttgcag
    18121 gaaattcagt tagaaatatt aggtagtgtt tgtcaaatac taggcaaagg tggtataata
    18181 acttatagca cctgcactat cgtctcagag gagaattttc aagtcgttaa ggccttttta
    18241 gagagtcatc ccgagttcga gcaggtaaaa ctagaacatg aatgtaagga tatcatgaaa
    18301 gacggctgta tcctcattac acctgaattg tatggaagtg atggattctt catcagtcaa
    18361 tttcgcaaga tatcggatta ggaaggaact gacacatgga aatttcatta ttaacagatg
    18421 ttggtcagaa acgaacaaat aaccaagact atgtcaacca ctatgtcaat agagctggac
    18481 gtaccatgat tattttagct gatgggatgg gaggtcatcg cgcagggaat atcgctagtg
    18541 aaatggcggt cacagacctg ggtgtagctt gggttgatac ccagattgat acagtcaatg
    18601 aagtgcgtga atggttcgcc cattacctag aaattgaaaa tcaaaagatt caccagcttg
    18661 gtcaggatga agcttacaga ggcatgggaa ctactttgga agtccttgct attattgata
    18721 atcaggctat ctatgctcat attggtgatt cgcgtatcgg cttgattcgt ggagaagaat
    18781 accatcagtt gacgagcgat cattccttgg ttaatgaatt gctcaaggct ggtcaattga
    18841 caccagaaga ggcagaagct catccgcaaa aaaatattat cacccagtct attgggcaaa
    18901 aagatgaaat tcagcctgat tttgggacag ttatccttga gtcaggtgac tatcttttgc
    18961 tcaatagtga cggcttgacc aacatgattt caggcagtga gattcgtgat attgtaacca
    19021 gtgatattcc tttagcagat aaaacggaga cacttgttcg ttttgctaac aatgcaggag
    19081 gtttagacaa cattacggtt gcccttgttt ctatgaacga ggaggatgca gaatgatcca
    19141 aatcggcaag atttttgccg gacgctatcg gattgtcaaa cagattggtc gaggaggcat
    19201 ggcggatgtc tacctagcca aagacttaat cttagatggg gaagaagtgg cagtgaaggt
    19261 tctgaggacc aactaccaga cggacccgat agctgtagct cgttttcagc gtgaagcgag
    19321 agctatggca gatctagacc atcctcatat cgttcggata acagatattg gtgaggaaga
    19381 cggtcaacag tatcttgcaa tggagtatgt tgctggacta gacctcaaac gctatatcaa
    19441 ggaacattat cctctttcta atgaagaagc agtccgtatc atgggacaaa ttctcttggc
    19501 tatgcgcttg gcccatactc gaggaattgt tcacagggac ttgaaacctc aaaatatcct
    19561 tttgacacca gatgggactg ccaaggtcac agactttggg attgctgtag cctttgcaga
    19621 gacaagtctg acccagacta actcgatgtt gggctcagtt cattacttgt caccagagca
    19681 ggcgcgtggt tcgaaggcga ctgtgcagag tgatatctat gccatgggga ttattttcta
    19741 tgagatgttg acaggccata tcccttatga cggggatagc gcggtgacca ttgccctcca
    19801 gcatttccag aaacccctgc cgtccgttat tgcagaaaat tcatctgtac ctcaggcttt
    19861 agaaaatgtt attatcaagg caactgctaa aaagttgacc aatcgctatc gctcggtttc
    19921 agagatgtat gtagacttgt ctagtagctt gtcctacaat cgtagaaatg aaagtaagtt
    19981 aatctttgat gaaacgagca aggcagatac caagactttg ccgaaggttt ctcagagtac
    20041 cttgacatct attcctaagg ttcaagcgca gacagaacac aaatcaatca aaaacccaag
    20101 ccaggctgtg acagaggaaa cttaccaacc acaagcaccg aaaaaacata gatttaagat
    20161 gcgttacctg attttgttgg ccagccttgt attggtggca gcttctctta tttggatact
    20221 atccagaact cctgcaacca ttgccattcc agatgtggca ggtcagacag ttgcagaggc
    20281 caaggcaacg ctcaaaaaag ccaattttga gattggtgag gagaagacag aggctagtga
    20341 aaaggtggaa gaagggcgga ttatccgtac agatcctggc gctggaactg gtcgaaaaga
    20401 aggaacgaaa atcaatctgg ttgtctcatc aggcaaacaa tccttccaaa ttagtaatta
    20461 tgtcggccgg aaatcttctg atgttatcgc ggaattaaaa gagaaaaaag ttccagataa
    20521 tttgattaaa attgaggaag aagagtccaa tgagagtgag gctggaacgg tcttgaagca
    20581 aagtctacca gaaggtacga cctatgactt gagcaaggca actcaaattg ttttgacagt
    20641 agctaaaaaa gctacgacga ttcaattagg gaactatatt ggacggaact ctacagaagt
    20701 aatctcagaa ctcaagcaga agaaggttcc tgagaatttg attaagatag aggaagaaga
    20761 gtccagcgaa agcgaaccag gaacgattat gaaacaaagt ccaggtgccg gaacgactta
    20821 tgatgtgagt aaacctactc aaattgtctt gacagtagct aaaaaagtta caagtgttgc
    20881 catgccgagt tacattggtt ccagcttgga gtttactaag aacaatttga ttcaaattgt
    20941 tgggattaag gaagctaata tagaagttgt agaagtgacg acagcgcctg caggtagtgt
    21001 agaaggcatg gttgttgaac aaagtcctag agcaggtgaa aaggtagacc taaataagac
    21061 tagagtcaag atttcaatct acaaacctaa aacaacttca gctactcctt aaaagcagat
    21121 ggataatcaa aatgagtaat caatctttgt catgatttca tggcaaagat tttttttgag
    21181 tccggatttg tgatagaata gagggagttg ataaaaggag gaaagcatgg aagaatcaaa
    21241 agaattaaat gccgtcattg atgtgattat gctagcgggg actattctcc ttaaaagtgg
    21301 ctcagaaatc catcgtgtag aagataccat gattcgaatc gcgcattcgc aggggattgt
    21361 ggattgcaat gtccttgcca tgcctgccgc tatctttttc tctattgaaa ataccaatat
    21421 ttcgcgcatg aagcgcgtga cctcctcttc ttataacatc gaaaaagtct gcgatgtgaa
    21481 ccagatttct cgtcagctag ttggggggca gattgactta gaaacagcct ttaagcaatt
    21541 gacggccttg caagccaaac cccttcccta tactaagttg caggtaactc tggctgcgac
    21601 ctttagtgct cctttctttt cagttatgtt tagcggaaat atctacgacg cacttggggc
    21661 aggagtggcg accttatttg gttttgcctt ttccctctat gtggaaaaat ttatccgaat
    21721 tccctttgtg acagcctttg ctggagcctt tgtctttggg ataattgccc agttttgggc
    21781 tcgctacaca ggttttcctt caacggcaga tttgattata gctggtgcgg tcatgccgtt
    21841 tgtaccaggt attgccttga ccaatgcggt ccgtgatatt atgaccaacc acataaactc
    21901 tggtatgagt aagatgtttg aatccctgct cattaccctc gctttagggg caggaacttc
    21961 tgtcgccttg gtattgatga actaatatga cactaacaac ctttttatta caagcagtag
    22021 caagttttct tgccattatc acttttttaa tcgtactcaa tgtgcaacgg tctatgctct
    22081 tacctggagg gattttgggc atgactgtct ggctaatcta tctcttgctc aaggaaccga
    22141 ccaatgtcat tgtagctacc ttcattgcag ccattattgg ttcttgtgtc agccagattt
    22201 taagtattct ttataagaca cctgctgtgg tctttatctt ggccattttg gcaccgctgg
    22261 ttccaggtta tctctcctac cgaacaactg ccttttttgt gacaggggac tataataaag
    22321 cactggcaag tgcgaccttg gttgtcatgt tggctttggt aatctctatt ggaatggcta
    22381 gcggaacagt gattctcaga ctgtatcatt atataaaaac acatcgagta tcgtagactt
    22441 tacagaaata aaagaatttt ctgaaaaatg agataaataa attaacaacg ctttctatat
    22501 gtgcgagaat accgcactta tgaagaaatt gcggctgatt ttggtatcca cgaaagcaac
    22561 ttactccgtc ggagccaatg ggttgaagta actcttgttc aaaggtggtg ttacaatttc
    22621 aagaactcct ctcagttctg aggacatggt aatgattgat gtgacggaag taaaaatcaa
    22681 tcgccctaaa aaacaattag cgaattattc tggtaaaaag aaatgccacg ctatgaaggc
    22741 tcaagcgatt gtcacaagtc aagggagaat tgtttctttg gatatcactg tgaactattg
    22801 tcatgatatg aagttgttca aaatgagtcg cagaaatatc ggacaagctg gtaaaatctt
    22861 ggctgacagt ggttatcaag ggaccatgaa gatatatcct caagcacaaa ctccacgtaa
    22921 atccagcaaa ctcaagccgc taacagctga agataaagcc tataaccatg cgctatccaa
    22981 ggagagaagc aaggttgaga atatctttgc caaagtaaaa acgtttaaaa tgttttcaac
    23041 aacctatcga aatcatcgta aacgcttcgg attacgaatg aatttgattg ttggtattat
    23101 caatcatgaa ctaggattct agttttgcag gaagtctact attttcctta ttgtctgtaa
    23161 gtctactgac cttgttgttt atcccagtca tggtttctag ttcgggctca gagtttcaaa
    23221 gtggatggca agagcatcaa ttgattgctg agaaggttag taaaacactt gacaagacat
    23281 ttgataagga tgtcagagaa attccgacca gtcagtttta tcaaaaattt gtagatgaga
    23341 tgggaaggac ttactcagga aatttgatcc tccaggagct gataactgtg aatggagctt
    23401 ataaagctac ttatataggt gaactctcta gcaactaatc attctttaaa atgatgacca
    23461 ataagaggct tgatttggtg aatcaagtct tttttctctc ttttactgcc atttgtgata
    23521 aaatagtata gaacgatttt ttacatgaat gataaaacag aggtaaatat gacaatcggt
    23581 attgataaga ttggttttgc gaccagtcaa tatgtcttga aattacaaga cttagcagaa
    23641 gcgaggggga ttgaccctga aaaattaagt aaaggactct tactcaagga attgagtatt
    23701 gcgcccctaa ctgaggacat cgtgaccttg gcggccagtg ctagtgactc tattttaact
    23761 gagcaagaaa gacaagaagt tgacatggtc attgtggcga ccgagtcagg aattgaccag
    23821 agtaaggctg cggccgtctt tgtgcatggc ttgctgggca tccagccctt tgctcgtagt
    23881 ttcgagatta aagaagcctg ctatggggcg acagctgccc tccattatgc caaattgcat
    23941 gtggaaaatt ctccggagtc caaggtattg gtcattgcca gtgatattgc caaatatggt
    24001 attgaaactc cgggagaacc aactcaaggt gctggaagtg tagctatgtt gattacacaa
    24061 aatccacgca tgatggcctt taataatgac aatgtagctc agacccgtga catcatggat
    24121 ttctggcgac caaattactc gacaactcct tatgtaaatg gtgtctattc tacccaacaa
    24181 tacttggata gtttgaaaac gacttggctt gaatatcaaa aacgctacca gcttactttg
    24241 gatgattttg cggctgtttg tttccacttg ccttatccta aattagcgct aaaaggcttg
    24301 aaaaaaatca tggataagag cctgcctcaa gagaaaaaag acctcttgca aaagcatttt
    24361 gaccagtcta ttctctacag tcaaaaggtg gggaatatct acacaggttc acttttcctt
    24421 ggacttttgt ctctcttgga aaatacagat agcttgaaag ctggggataa aatcgccctt
    24481 tatagttacg gaagtggagc tgtggctgag ttcttcagtg gtgaattggt tgaaggatat
    24541 gaagcttatt tggataaaga ccgtttgaac aagctcaacc aacgaactgc cctatccgtt
    24601 gcagactatg aaaaggtctt ttttgaggaa gtaaacttgg atgaaacaaa ctctgcccag
    24661 tttgctggct atgaaaatca agattttgcc ttggttgaaa ttcttgacca ccaacgccgt
    24721 tatagcaagg ttgaaaaata atgaagataa gttggaatgg attttctaaa aaatcatacc
    24781 aagagcgcct cgagctgcta aaagctcagg cgctccttag tcctgagaga caagctagtc
    24841 tggagaagga tgaacagatg agtgtgactg tggcagacca gctgagtgag aatgtggtgg
    24901 gaactttttc tctgccttat tcgctggttc cggaggtact tgtcaacggt caggaataca
    24961 ccgttcccta tgtgacagaa gaaccctctg tggttgcggc ggccagctat gccagcaaaa
    25021 tcatcaagcg tgcaggtggt tttactgcac aagtccatca gcgccagatg attgggcagg
    25081 tagcccttta tcaagttgct aatcctaaac tagcgcaaga gaagattgcc agcaagaaag
    25141 cggagctctt ggagcttgcc aatcaagcct atccttctat cgttaaacgt gggggtgggg
    25201 cgcgtgatct gcatgtcgag cagataaaag gcgaaccaga ctttctcgtt gtttatattc
    25261 atgtcgatac ccaggaagcc atgggtgcca atatgctcaa caccatgctg gaagccttga
    25321 aaccagtctt agaagaactc agtcagggac agagtctcat gggaatcctg tccaactacg
    25381 cgactgattc tctggtgact gcaagctgtc gcatcgcctt tcgctacttg agccgccaaa
    25441 aggatcaagg acgagagatt gcggagaaaa ttgcgttggc tagtcagttt gcgcaggctg
    25501 atccttaccg agctgctact cataataaag gaatttttaa tggtattgat gcgattttga
    25561 ttgccactgg taatgactgg cgtgccatcg aagctggggc ccatgccttt gccagtcgag
    25621 atggacgcta tcaaggtctt agttgctgga cgctggacct tgaaagagaa gaattggtcg
    25681 gtgagatgac cctgcccatg cctgtagcga ctaagggtgg ctctatcggc ctcaacccac
    25741 gtgtagctct cagtcatgat ctactaggaa atccttctgc cagagaatta gcccagatta
    25801 tcgtgtccat cggtcttgcc caaaattttg cagccctcaa agccttggta agtacgggca
    25861 tccagcaagg ccacatgaaa ctacaggcca aatccctagc tctcctagct ggggctagtg
    25921 aatctgaagt tgctccccta gtagagcgcc tcatctcaga taaaaccttt aatctagaga
    25981 cagcccagcg ctatctcgaa aatttaagat cataaaaact cagacgaatc ggtctgagtt
    26041 ttcttgtgtt taaatacttt ttcctggtaa tagtgtaact ggtaagaagt aaccagttgt
    26101 ggcgacttcc ttgccttcaa tcttttgcaa gagaagatca atagtgagac aagcaatctc
    26161 ttccaaaggt tgcttgatag tagccaattg agggtagtaa ttttcgataa agtaggtccc
    26221 atcatagcca atgaccttga gctcttttgg gacagaaatg cccaattctt gagcgatttt
    26281 aatgaccaga atagctgtca aatcatccga agcaaaaatg gcatctggtt tttcccgggt
    26341 caagatattc ttgatttcca tttcttttct gacgggagaa aagtcactgg aaacattgat
    26401 aataggagct tttgggagta cggatgcaaa accagcgtgg cgcagtccgg ttggcgaatt
    26461 ggaattgtca ttccctgtaa tcatgatgat agactgggca cctgtcttga ccaaggtttg
    26521 ggcagcaaga accccaccag catagttgtc agaggagaca acagggatgt ctggcgatag
    26581 gtttcggtca aaggaaataa tcggcgctgt cacacgattg tagtcttcga ttcctaggtt
    26641 gtgactacca gaaatgatgc cgtctacctg attggcttcc aacatttcga tgtattcgcg
    26701 ttccttctca gaatcatgtt cactgttgca gatgatggtc ttgtaaccat ttttgaagag
    26761 ttggtgttcc aatttatcaa tcaattctgc atagaaaaca ttggaaatat tggggaaaat
    26821 caagccgatt aacttagctg attttccttg cagactacga gccaggttgt tgggtttata
    26881 gcctaattct ctcatggctt cattgacttt ttggatggtt ttctcagata gatatccttt
    26941 tttattgata acccgagaaa cggtagtagg actgacgcct gcaagtttgg cgacatcagt
    27001 tagttttgcg accataatct aattcatagt aagttccagt tgggtttcca gatttgatca
    27061 ggataccatt ttggtccgca tgtgggaaga cacgaccaga aaatactttt tctcctttat
    27121 tgatgaaaat ttcaaagaca gagttatcga tgaagattgt agcagtagta gcctgattct
    27181 cgatagggca agaacgagtt gtcccaaatt cttgggcata ttgttctcca gcctggctac
    27241 gatccactgt cacttgaccg tttacaaggt caaagttgat tgaaagtccc ttaccttctt
    27301 tatcagcaag taagacaatc tcgctctggc tattagcttc caagttgagt tcaagttcgt
    27361 aagtgttctt ggtttgggaa cggtttgaga aggcttcttc agaagcacga aggtccttaa
    27421 tagcagcgac tggatactgg tagagcttgt cgtctttgat agtgagttcc ttgaccaaag
    27481 agaaggttcc ttggtgatca aaacagtcag atgggtaaga aacatctggc aaaccaagcc
    27541 agctaactgc tagagcacgc ccatcaggag cgttgaaggc ttgagttgca taggcttcga
    27601 aaccgtaatc catgttttga agttgagaca catctaccat tttggcattt ttagggtcaa
    27661 aggaagcccc aatcttatac atatttggaa agatattatc gtagtctaga actttcttat
    27721 ccaatccttg tggacagtag agaaggacag gctgttcctc tacaaagacc agattaggac
    27781 attccatcat gtaggcagta cggtcgttag caaagtcaag gtcgccaact gcttgccagt
    27841 ttgtgtagtc gttattgaca gccttgtaga gacggacgaa gccttttttc tccaagtcct
    27901 gtccaccgac gacagcatag tattgacctt taaagttaaa aatttgtgga tcgcggaagt
    27961 ggtcagtaga gtctgctggc tggtcaatca agatcttgtc aatctttgta atcttaccct
    28021 ccttgtccat caaagcaccg atctggtatg ggtgacggat ccagttttca tcgcgaacat
    28081 ttcctgtata aaataggaat aagttatcgc caaattgtat ggcagaacca gagtaggcac
    28141 cgtggctatc taatggagta tctggtaaaa ctttgattcc agtttcttta aagtgaacca
    28201 aatcatcact ttctagctgt gcccaagatt tcaaaccgtg ggctgcacca aaaggaaaat
    28261 tctggtaaaa gaggatccac ttgccatcaa agtaagaaaa gccatttggg tcgttgagaa
    28321 gtcctgtttt tggctcaaca tggtaatgag tatgccatgg agattgtgcc atattttcct
    28381 ttatatgttg aatttcttct tgcgtccaat cttgataaag tctgtaacga cgctcagttg
    28441 tccattccat tcattcctcc aaaaatctta tcacttttaa tagtaactgt tttcgataaa
    28501 aaatgcaagc cttttatgtt aaaaaagagg aaaaactgtc aaacgattat cataaaataa
    28561 atacaggaaa tcaattaaat ttttacgaaa atgtgaaaga taatgaaata aaatactttt
    28621 taaccaaggt ttcaaactta tttttcaagg aattcctgat gaaacagtca aaaacaatca
    28681 atctaaagct tgcccactaa gtggatagaa tatttttatg caaaacgctt gacatatttt
    28741 taaaacatga taaaataata gtcgtaaggg cgaataaaat cgctttcaaa caagaacaaa
    28801 atgttatata aggagatttt tgcaaatgaa caatcaggaa attgcaaaaa aagtcatcga
    28861 tgccttgggc ggacgtgaaa atgtcaatag tgttgcccac tgtgcgactc gtctacgtgt
    28921 catggtcaaa gatgaagaga aaatcaataa agaagtgatt gagaacttgg aaaaagttca
    28981 aggtgctttc tttaactcag ggcaatacca aattatcttt ggtacaggta cagttaacaa
    29041 aatgtacgat gaagttgttg tacttggatt accaacatca tctaaggatg acatgaaagc
    29101 agaagttgct aaacaaggga actggttcca acgtgctatc cgtacttttg gtgatgtttt
    29161 cgttccaatc atcccagtta tcgtagcgac aggtctcttc atgggtgtgc gtggtctttt
    29221 caacgctctt gaaatgccac ttccaggtga ctttgcaact tacacacaaa tcttgacaga
    29281 tacagccttc atcatcttgc caggtttggt tgtgtggtca accttccgtg tatttggtgg
    29341 aaatcctgcc gttggtatcg ttcttggtat gatgcttgtc tctggctcac ttccaaacgc
    29401 ttgggcagtt gctcaaggtg gtgaagtaac agcgatgaac ttttttggtt tcatccctgt
    29461 tgttggtttg caaggttccg ttcttccagc cttcatcatc ggggttgtcg gagctaaatt
    29521 tgaaaaagct gtccgcaagg ttgttccaga tgtcattgac ctcttggtaa caccattcgt
    29581 gacacttttg gtcatgtcta tccttggact ctttgtcatt ggaccagttt tccacgttgt
    29641 tgaaaactac atccttattg ctacaaaagc gattcttagc atgccatttg gtcttggtgg
    29701 tttcttgatt ggtggggttc accaattgat cgtcgtgtca ggtgtgcacc acatcttcaa
    29761 cttgcttgaa gtgcaattac ttgctgctga ccatgctaac ccattcaacg ctatcatcac
    29821 agctgctatg acagctcaag gtgctgctac tgttgcggtt ggtgttaaaa caaaaaatcc
    29881 aaaactgaaa acacttgctt tcccggctgc tctttctgcc ttcctaggta ttacagagcc
    29941 tgctatcttc ggggtgaact tgcgcttccg taaaccattc ttcctttcat tgattgctgg
    30001 tgcaatcggt ggtggattgg cttctatcct tggacttgct ggtactggta atggtatcac
    30061 catcatccct ggtacaatgc tttatgttgg taacggacaa cttccacaat accttcttat
    30121 ggtagctgta tcatttgccc ttggttttgc tcttacttac atgtttggtt acgaagatga
    30181 agtagacgca actgcagctg caaaacaagc tgaagtggct gaagaaaaag aagaagttgc
    30241 gccagcagct cttcaaaatg aaacacttgt aactcctatc gtcggtgatg ttgtcgctct
    30301 tgctgatgtc aatgacccag tcttctcaag tggagctatg ggacaaggta tcgctgtgaa
    30361 accaagccaa ggcgtggtct atgcaccagc tgatgctgaa gtttcaattg cctttccaac
    30421 agggcacgct tttggtttga aaacaagaaa tggtgctgaa gttttgattc acgttggtat
    30481 tgacactgta tctatgaacg gtgacggttt tgaagcaaaa gttgctcaag gtaataaggt
    30541 gaaagctggc gatgttcttg gaacatttga ctcaaacaaa atcgctgcag ctggacttga
    30601 tgatacaaca atggttatcg ttacaaatac aggtgactac gcttcagtag ctccagtcgc
    30661 aacaggttca gttgctaagg gggatgctgt gatcgaagtg aaaatctaat caatcctctc
    30721 taatgtgaaa acgaacaaat gacatgtttg ttcgttttta ttagatagta agatttacag
    30781 aggaaaatct aaaaaataga gacatttaga ctttcgaagt atgctataat aaagaaaata
    30841 aaaacaagag gtttatcatg acaaaattat atggaagctt ggaagcgggc ggtacaaagt
    30901 ttgtctgtgc tgtcggtgat gaaaacttta acgttgtaga aaaaacacaa tttccaacaa
    30961 caactccaat cgaaacaatc gataaaacca ttgagttctt ctcaaaattc gataaccttg
    31021 ctggtcttgc agttggttca tttgggccga ttgatattga caaaaactca aaaacttatg
    31081 gctttatcac gacgactcca aaaccaaact gggcaaatgt ggacttgctt ggtgcccttc
    31141 gtcgcgccct aaacgtgcca atgtacttca caacagacgt aaacagctct gcttacggtg
    31201 aagtggttgc ccgtaacaat gctggtggtc gtatcgaaaa cttggtttac tacacaatcg
    31261 gtacaggtat cggtgcaggc gtcatccaac gtggtgagtt tatcggtggt gtgggtcacc
    31321 ctgaaatggg tcattattat gttgctagac acccaatgga tattgaaaaa gagtttaagg
    31381 gtgtttgtcc tttccataag ggatgtctag aaggttatgc agctggtcca agtttggaag
    31441 ctcgtacagg tgtacgtggg gaaactattg aactcaacaa ccctgtttgg gatgttcaag
    31501 cctactatat cgctcaagct gcggttaatg cgacagtgac tttccgccca gacgtgattg
    31561 tctttggtgg aggggtcatg gctcaacaac atatgctgga ccgtgtccgt gagaaattta
    31621 catctcttct taatggttac ctaccagtac cagatgtgcg tgactatatc gtgacgccag
    31681 cagtcgcagg aaatggttct gccacacttg ggaactttgt tcttgcaaaa gaagtttcaa
    31741 aataaagcac aaaatccgct tgggaaacca aacggatttt gtggttgaaa acaatatttt
    31801 tgagcctttc cttaagtgat tacggacggt agcgactttc ttcgaaattc catacctaaa
    31861 ctttgagcct agtgtctcaa agtttccgaa tacctgaaac cattagattt caggtgtttc
    31921 tatcacggcg gaaaggctag gtaagtcctc gcctcactat cgaaaaatat gcatgatttc
    31981 cataccaaag tatatttagt atcaagctat agttaatcta cgctttaaaa atccacttgg
    32041 gaaaccaaac ggatttttta cgtgtcaaag catttgccag aaaaagtcaa taatataggt
    32101 cagaccgtag gtataaacca cgagggtaaa gggtttggtc agaatgatga tggtcatgta
    32161 gcgcttgaaa ctcatcttgg tcagggcagc cagcatacag agaaagtcag ctgggctaat
    32221 gggccaaatc atcataaaaa taaagaagcg gtcaaaacga ttgcccttat ctagccagcc
    32281 gatgtacttg tcgtaggtgc gcttgctgac gacagactgg acaaaggcag ctccgtatag
    32341 gcgcactaga taaaagataa tggcacagcc aatcacgatg ccgatatagt tgtagatagt
    32401 cccgatgatg tgcccgtaga taaagacccc agccaccgag gtcaaggccc ctggaatgat
    32461 agggacgaca gtctgtaaaa tctgtaaaaa gataaagaga ggtggacccc agatgcctgc
    32521 ctgctggata aaggcagaga gggtttcctt ggattgtaaa atcccagcct gataagccca
    32581 aatacagaaa atcaaactcc caaccccacc gacaatcgat gagatattga taactcgctg
    32641 cagaagggga gaaacagctt tcatttgttt atcctgtgac atgtaaactc ctcatagata
    32701 gtatatttct actataccat attttggagg agaaaggggg aatgagtctt ttttgataag
    32761 gaatagaaag taaatagccc ttcgagactt agaataggtc tgtcaactaa aggttatatg
    32821 cattctaggt ttcgaataat cgcaattcca taaatttaaa agcattctaa gtttcgaata
    32881 gcttatctga gataattttg aggcattcgc gctttcgaat agtcattttc cctaaagttt
    32941 agatgtattc tgaagctaga aagactaaaa tctaaaagta gtaagagtct ctctctgatg
    33001 gacgtaattt atggctagta tgaatccttt gaattgttag ttaattttaa tattaatcag
    33061 ttctgaaata attactaaat atagttagat ggtgaattaa ttattgctaa atttcaagtt
    33121 caagttcaag ttagtcatcc agaagtcttc tctgggggac ttgtagttca agcatttttt
    33181 aggatagttg ttaatccact tttcgatgaa tgcgacttcc tttgtagtcg ttttcttagt
    33241 tccctgaggt aaccatctat gaatgaactt gttgtgattt ttattagatc ctatagtggt
    33301 gtgcataata gatataatag attgaaacta gaatagtacg catctacttc taaaacattg
    33361 ttagaaatcg atttgactgt cccgatctat ttgtcctgtt tttatttcat tttactatat
    33421 aatccttaga aaacatatcg gacaagcggt tgaattccgt tccgtccatt agtagataaa
    33481 ggattactcc ttcttgaaat gacagatgaa cttgtttctt ataaaaatgt tgtctgaaac
    33541 tattcgcttt tttccagaag ttttagagga agaaaacttt atgaggaaaa aggagttact
    33601 caaataacaa ttcaggatta aaaatagaca gttgaggagc ggaaggtata aattaagttt
    33661 gctactgtat aatggattta tcactaatac tcttcgaaaa tctcttcaaa ccacgtcagc
    33721 ttcgccttgc cgtagatata gttactgact tcgtcagttc tatccacaac ctcaaaacag
    33781 tgttttgagc tgacttcgtc agttttatct gcaacctcaa agctgtactt tgagcagcct
    33841 acggctagct tcctagtttg ctctttgctt ttcattgagt ataaaagtgc tccaggccat
    33901 attttacaca gcaatagtct tctaaaaatg gacaaaaaca ttgtaaaggc tatcaaaaag
    33961 gagtataatg agtgcaagaa atttcggagg tgaaagatgc tagaagtaag aagtctagag
    34021 aaaagttttg gctccaagca agttttgttt ggtattgact ttcaagcgcg accaggtcgt
    34081 attttgggac tagtcggaaa aaatggtgct ggaaaaacaa cgattttcca tagtattttg
    34141 aaattcctag aatatcaggg agaaatcggt ctggatggtc aggatattcg tcaggagacc
    34201 tatgctcgga ttggttatct gcctgaagaa cgcagtctca tgcctaaatt gacagttctt
    34261 gaacaagttc gctacttggc gactctaaaa ggcatggatg ccaaagaagt caaagaaaaa
    34321 ctccctcaat ggatgaagag gttggaagtg aaaggaaagc tgacagataa aatcaagagt
    34381 ctgtcaaaag gaaatcagca gaagattcag ctcattatta ctctgattca tgaaccagac
    34441 ctgattatct tggatgagcc ttttagtgga ttggacccag ttaatacaga attgctcaaa
    34501 caagtcattt ttcaggaaaa agagcgcgga gcaaccatta tcttttctga ccatgtcatg
    34561 accaatgttg aggaactttg tgacgatatt ctgatgatcc gagatggccg tgtggtcttg
    34621 cacggaccag ttcaggatgt ccgcaatcaa tacgggaaaa cgcgtctctt tgtttcaagt
    34681 gaacgaagca aggaagaatt ggaaaatctt cctcatgtca aacaggtgag cttgaccaaa
    34741 caaggcagtt ggaaattgat tttggaggat gagagcgctg gaagggaact cttcccaatc
    34801 ttgactcaag gtcaatatat cgcaacattt gaccaacaag cgccaactat cgatgaaatc
    34861 tttaaactag aatcaggagt ggaagtatga gaaatatgtg ggttgtaatc aaggaaacct
    34921 atcttcgaca tgtcgagtca tggagtttct tctttatggt gatttcgccg ttcctctttt
    34981 taggaatctc tgtaggaatt gggcatctcc aaggttcttc tatggctaaa aataataaag
    35041 tggcagtagt gacaacagtg ccatctgtag cagaaggact gaagaatgta aatggtgtta
    35101 acttcgacta taaagacgaa gcaagtgcca aagaagcaat taaagaagaa aaattaaaag
    35161 gttatttgac cattgatcaa gaagatagtg ttctaaaggc agtttatcat ggcgaaacat
    35221 cgcttgaaaa tggaattaaa tttgaggtta caggtacact caatgaactg caaaatcagc
    35281 ttaatcgttc aactgcttcc ttgtctcaag agcaggaaaa acgcttagcg cagacaattc
    35341 aattcacaga aaagattgat gaagccaagg aaaataaaaa gtttattcaa acaattgcag
    35401 caggtgcctt aggattcttt ctttatatga ttctgattac ctatgcgggt gtaacagctc
    35461 aggaagttgc cagtgaaaaa ggcaccaaaa ttatggaagt cgttttttct agcataaggg
    35521 caagtcacta tttctatgcg cggatgatgg ctctgtttct agtgatttta acgcatattg
    35581 ggatctatgt tgtaggtggt ctggctgccg ttttgctctt taaagatttg ccattcttgg
    35641 ctcagtctgg tattttggat cacttgggag atgctatctc actgaatacc ttgctcttta
    35701 ttttgatcag tcttttcatg tacgtagtct tggcagcctt cctaggatct atggcttctc
    35761 gtcctgagga ctcagggaaa gccttgtcgc ctttgatgat tttgattatg ggtggttttt
    35821 ttggagtgac agctctaggt gcagctggtg acaatctcct cttgaagatt ggttcttata
    35881 ttccctttat ttcgaccttc tttatgccgt ttcgaacgat taatgactat gcggggggag
    35941 cagaagcatg gatttcactt gctattacag tgatttttgc ggtggtagca acaggattta
    36001 tcggacgcat gtatgctagt ctcgttcttc aaacggatga tttagggatt tggaaaacct
    36061 ttaaacgtgc cttatcttat aaatagaaga gccttgcgaa agcgaggttt ttaaaggtga
    36121 aaagggtgga atcacgaacc taattatgta cacattatgt aaacaagttg cttgaaaact
    36181 caattgtata gtgaactgaa tctggaatag gataatatta cttctaaaac attcttacaa
    36241 attgatttga attccaaaat cccatcgttc cgttcttatt tcattttgcg atatagtgaa
    36301 aggaaataag tcagctcaca aaaaacgcat aatatcaagg attttttgaa ctgcccccca
    36361 aaagttagat tttttctgtc taacttttgg ggggcagttc atattcaaca cttgatacta
    36421 tgcgttttct aattttaaag actttttgcc tggtctcttt tgttctatga gtatgttaca
    36481 tatctaggta aaaattattt aaagcaaatt aaccttattt ctcaagatgt agtaggttcc
    36541 gagataaaag atagctatga atatgagttc ttcaacaatg gctatacctg ctcccatata
    36601 gaaatggtca ttgagtccta ccagtgaatt gacatagaaa ttagaactaa gattgaagaa
    36661 aagttcaata aatccaatga cgatttggat accaatgtag actgcaacag cgagtgctgt
    36721 acggtattca ttgaaaagct gtccaatgga aatagccagg tagatgcaga ggattcctga
    36781 aatggtattt agtaggaagg atatacctgt aagaaagatc tgagggagat gtgtttctac
    36841 aaatgtaatc acataagaaa gaggaatcca ttctggagct gttaaagcca gaataataac
    36901 agcacttaga gccaatacag cggtgctaat caatgaccag ataaaggcac cgattagttt
    36961 ggctgtgatg atatggtgtt cagaaactgg caaggtcaaa gtcagatagc cttgtcggtc
    37021 gtagacacta cctttgaagc gtttaataat caagaaaatg gttgaaatcg caagtgtaag
    37081 catcaagcca ccaaagactg tagctagaaa aagtagcata gtagcctgac tttcttggta
    37141 aggtagattt ttaaagcctt gtgtctgtat tccgatgagg gcagaaagga ctagcacggc
    37201 tgcgtagagg gctaaatacc acttgttaac atttttaaat tcgtagtgaa ctaaattcca
    37261 aaacataaat aatctccttt gcttaggcct taaattcctg acggaagagt tggtcaatgg
    37321 attcacctga ctcgtagcga atatcatcta catttccttg acggacgact tttccgtctt
    37381 ttaggaagac aatttcatcc aagattggct cgatatcaga aatcaagtgg gtagaaatca
    37441 aaacggtaga agttggtgag tagttgttga taatggtatt gaggatataa gcacgggctg
    37501 ctggatccac cccaccaatg ggttcatcca aaacatagag acgagcatca cggctcataa
    37561 ccaaaatcag ttgaaccttt tctttgtttc cttttgatag tttcttgaga cgactatttt
    37621 catcaatgcc caggtctgca agtagatgat gggcgcgttc aagattgaaa tctttataga
    37681 aggtcttgaa gtaggttagg gcttctttga ccttcatttg ctcattgaga taggtcgtat
    37741 caggcaaata agctacaacg gccttggttg ctgggcttgg gtccatgtcg ttgatgagga
    37801 cacgtccttg atctggttgt aagaggccat taattagttt aatcagggtt gtttttcctg
    37861 agccgtttgg cccaagaagg ccgacaattt ttccagctgg aatgtcaaga gaaacatttt
    37921 caagggctgg tgttgctcca tatgatttgg atacattttc aaatgctagt aatgacatag
    37981 gcttaaactc ctttaatata atcactgact acgcctggta gttcttcttt ttcatagcca
    38041 aaatgggtca tggaggaaac gaagtgttcc aattcttctt ctgataattg tttgcgtgac
    38101 tgggcgatta gctccttatc cttagtcaca aatcgtccag ttgttcgctt gctgtagaca
    38161 aatccttctc gttcaaggtc tgataaggct ctttggatgg tattgggatt gacaccagcc
    38221 tcgctagcta gctccctcac ggttggaagt tgttgattgg gttccagtgt atgggaaaca
    38281 atctgaagct tgattttttc cataatctgt aaatagatgg gttttttgtt gtcaaatgtc
    38341 caggacatct tggtctcctt tctcttaccc ttttgtctta attaaataat acaacaaaac
    38401 aaaaaacttg tcaagcaaaa agaagaattg ttttgggaat cgcttaaaaa atggtataat
    38461 gaaaagaaaa cgataaggag ggaaaggatg cgttgtccaa aatgtggggc taccaagtca
    38521 agtgttatcg atagtcgcca agcagaagaa gggaacacca ttcgtagaag acgtgagtgc
    38581 gacgaatgcc aacaccgttt tacaacctac gaacgagtag aagaaagaac cttagtggtt
    38641 gttaaaaaag atggcacacg ggaacaattc tccagagata aaatctttaa tgggattatc
    38701 cgctcagccc agaaacgtcc tgtgtcaagt gatgaaatca acatggtagt caatcgtatc
    38761 gaacagaaac tccgtggtcg aaatgaaaat gaaattcaaa gtgaggacat tggttcactc
    38821 gtcatggagg agttggctga attggacgag attacctatg tacgttttgc tagtgtctat
    38881 cgtagtttta aggatgtcag tgagttagag agcttgctcc aacaaatcac ccagtcctct
    38941 aaaaagaaaa aggaaagata aatgaagcca attgaccgtt tttcttatct aaagaataat
    39001 cgggtgtcgc aagatacctc atctctggta cagtgctacc tcccgattat cggtcaggag
    39061 gcactgagcc tttatcttta tacgattagt ttttgggata atggtagaaa ggaatatctt
    39121 ttttcaagta tcctcaatca tcttaacttt ggaatggata gactgataaa atcattgaaa
    39181 atcttatctg cttttaatct cttgactctc tatcaaaagg gggatgttta tcagctagcc
    39241 ctccatgctc ctctatctag tcaagacttc ttggggcatc ctgtttatcg cagactctta
    39301 gagaaaaaga ttggggactc tgctgtggag gatttgaaag ttgaaagtgc tgatggtgaa
    39361 gaaatacctg tctcactcaa tcaagtcttt ccagaattgg cagaactagg cagtcaagaa
    39421 gaccttggtc tcaagaagaa agtggccaat gattttgact tggaacattt tcgccagctg
    39481 atggctcgag atggacttcg ttttgcggat gagcagtccg atgtcttaaa cctctttgct
    39541 attgccgagg agaagaaatg gacttggttt gaaacctatc aattggccaa gtcaacagct
    39601 gtttctcagg ttatttcaac caaacgcatg cgtgaaaaaa ttgctcaaaa accagtttcc
    39661 tctgacttta gtcttaagga aacaaccatt atcaaagaag ccaaaagtaa aactgccctg
    39721 cagttcttgg cagaaatcaa gcaaacacgc aagggaacca ttacccaaac agaaagagaa
    39781 ctcttgcaac agatggctgg cttgggcttg ctggacgaag tcatcaatat cattctttta
    39841 ttgaccttta ataaggtcga ttcggcaaat atcaatgaga aatatgccat gaaggtagcc
    39901 aatgactatg cctatcaaaa gattcattcg gcagaaaagg cagtcttgcg catccgtgag
    39961 cgagaacaga aagcaaaaac acaaaaacag aatcagactg ccccagcaaa aaccaatatt
    40021 cctaaatgga gtaatcctga atataaaaat acgtcatccg ctgaggaatt agaagagatg
    40081 gaacgccaaa ccctagaatt attagcaaaa ttagataacg gaggtgatta gatggaaagt
    40141 gtcggagatg tactcaaacg tcaaccaagt cgttttcact atcaagattt agttcagaaa
    40201 atcatgaagg atcctgatgt tgcggccttt gtccagcaag aatccctcaa tcaggacgag
    40261 ttgaaccgta gtatttccaa gtttaaccaa tacatcactg agagagataa attcctccga
    40321 ggagatacag attatattgc caaaggctac aagcctatat tagtcatgaa ccatggctat
    40381 gcggatgttt cttatgaaga aactcctgaa ctaatcgcag ctgaaaaaga agcggctatc
    40441 aagaaacgtc tcaacttaat taattttcca tctagcctga aaaatgtcag ttttttagat
    40501 gtttatcgtg atgatgttca gcgcttaact gttctaaaaa gaatgataga atttgttaac
    40561 gattacccca ataatttgaa aggtctttac ttgtatggag actttggtgt gggtaaaagt
    40621 ttcatggtgg ctgccctagc tcatgattta tcagaaaaac gtggtgtatc atccactctc
    40681 ctccactatc ctagctttgt cattgatgtc aaaaatgcta tcagtgatgg caatgttaag
    40741 accttggtgg atgagattaa gctgtctgat gtcctgattt tagatgatat tggcgccgag
    40801 caatcaaccg tttgggtgcg tgacgaaatc ctgcaggtca ttctccaata tcggatgcag
    40861 gaaaatttac cgaccttttt cacatccaac ttcaactttg aagatttgga gaagcatttt
    40921 gcgaaagtga aacatggaaa tgacgaaacc tgggaagcca gacgggtcat ggaacgcatc
    40981 cgttatttgg ctgaggagac tcgtttagaa ggagtaaacc gtcgatgaca gaaaccatta
    41041 aattgatgaa ggctcatact tcagtgcgca ggtttaaaga gcaagaaatt ccccaagtag
    41101 acttaaatga gattttgaca gcagcccaga tggcatcatc ttggaagaat ttccaatcct
    41161 actctgtgat tgtggtacga agtcaagaga agaaagatgc cttgtatgaa ttggtacctc
    41221 aagaagccat tcgccagtct gctgttttcc ttctctttgt cggagatttg aaccgagcag
    41281 aaaagggagc ccgacttcat accgacacct tccaacccca aggtgtggaa ggtctcttga
    41341 ttagttcggt cgatgcagct cttgctggac aaaacgcctt gttggcagct gaaagcttgg
    41401 gctatggtgg tgtgattatc ggtttggttc gatacaagtc tgaagaagtg gcagagctct
    41461 ttaacctacc tgactacacc tattctgtct ttgggatggc actgggtgtg ccaaatcaac
    41521 atcatgatat gaaaccgaga ctgccactag agaatgttgt ctttgaggaa gaataccaag
    41581 aacagtcaac tgaggcaatc caagcttatg accgtgttca ggctgactat gctggggcgc
    41641 gtgcgaccac aagctggagt cagcgcctag cagaacagtt tggtcaagct gaaccaagct
    41701 caactagaaa aaatcttgaa cagaagaaat tattgtagaa agtgagaaat tatggcccta
    41761 ccaactattg ccattgtagg acgtcccaat gttgggaaat caaccctatt taatcggatc
    41821 gctggtgagc gaatctccat tgtagaagat gtcgaaggag tgacacgtga ccgtatttat
    41881 gcaacgggtg agtggctcaa tcgttctttt agcatgattg atacaggagg aattgatgat
    41941 gtcgatgctc ctttcatgga acaaatcaag caccaggcag aaattgccat ggaagaagca
    42001 gatgttatcg tctttgtcgt gtccggtaag gaaggaatta ccgatgcaga cgaatacgta
    42061 gcccgtaagc tttataagac ccacaaacca gttatcctcg cagttaacaa ggtagacaac
    42121 cctgagatgc gaaatgatat ctatgatttc tatgccctcg gtttgggtga accactgcct
    42181 atctcatctg tccatggtat cggtacaggg gatgtactag atgcgattgt ggaaaacctt
    42241 ccaaatgaat atgaagaaga aaatccagat gtcattaagt ttagcctgat tggtcgtcca
    42301 aacgttggaa aatcaagctt gatcaatgct atcttgggcg aagaccgtgt tattgctagt
    42361 cctgttgctg gaacaactcg tgatgccatt gatacccact ttacagatac agatggtcaa
    42421 gagtttacca tgattgatac ggctggtatg cgtaagtctg gtaaggttta tgaaaatact
    42481 gagaaatact ctgttatgcg tgccatgcgt gctattgacc gttcagatgt ggtcttgatg
    42541 gtcatcaatg cggaagaagg cattcgtgag tacgacaagc gtatcgcagg atttgcccat
    42601 gaagctggta aagggatgat tatcgtggtc aacaagtggg atacgcttga aaaagataac
    42661 cacactatga aaaactggga agaagatatc cgtgagcagt tccaatacct gccttacgca
    42721 ccgattatct ttgtatccgc tttgaccaag caacgtctcc acaaacttcc tgagatgatt
    42781 aagcaaatca gcgaaagtca aaatacacgt attccatcag ctgtcttgaa cgatgtcatc
    42841 atggatgcca ttgccatcaa cccaacaccg acagacaaag gaaaacgtct caagattttc
    42901 tatgcgaccc aagtggcaac caaaccacca acctttgtca tctttgtcaa tgaagaagaa
    42961 ctcatgcact tttcttacct gcgtttcttg gaaaatcaaa tccgcaaggc ctttgttttt
    43021 gagggaacac cgattcatct catcgcaaga aaacgcaaat aaaaaagtag aatctggaat
    43081 gacagttccg gatttttttg atataataaa ataatagaaa acgctatcaa aagaaggagg
    43141 gtgatgtcgg tgatggaaca tttgtttaaa ttcttacttt tagcaccgta cttttatttt
    43201 gataactgga ttgaaaaggc caacagaaat agtaagtttt ttccaatttt ttattatttt
    43261 tactggtttt acatcccctt ctattctctt tttagccttg cttggacagt tgtttcagtt
    43321 ctgtttttca ataccgtctt gagaaatgtg acagatatca agttatgggg catttggttt
    43381 ctttttattc tgctagctat tggtatgaat tggttaactt attcctgttt caaagaaatg
    43441 tttcgcttga gacaggaact agggaagtct aagggtggaa ggcattgatt tatatcggtt
    43501 tctatttgta ggaggtggct tatgaagatt cctctcttaa ctttggcaag gcataaattt
    43561 gtttatgtct tgcttacttt gctttttctt gctttggttt atcgtgatgt tttgatgact
    43621 tatttctttt ttgatattca tgcgcccgat ctagctaaat tcgatggaca agcaattaaa
    43681 aatgacttat taaaatcagc attagatttt cgtattctcc agttcaatct aggtttttat
    43741 caatcattta ttattccaat tatcattgtt ttgctaggtt ttcaatatat tgagctgaaa
    43801 aataaagttt tacgattgag tattggaaga gaagtgagct atcaagggtt aaaaagaaag
    43861 ttgactttgc aagttgcaag tatcccttgt ttgatatatt tagtgactgt gctgataatt
    43921 gcaattataa cctatttctt tgggactttt tctcctcttg gatggaattc tctattttct
    43981 gatggaagtg gtttacaaag actcctagat ggagagataa aaagctattt gttctttact
    44041 tgtgtcctac taatcggtat tttcatcaat gcaatctatt ttttacaaat agttgattat
    44101 gtggggaatg tgactcgttc ggcaatcacc tatttgatgt ttctttggct tggttctatg
    44161 ctgctctata gtgccttgcc ttactatatg gttcctatga cgagtttgat gcaagctagc
    44221 tatggggatg taagtttgat gaaactcttt actccttata tcctttatat tgtcccttac
    44281 atggtgcttg aaaaatatga agataatgtt taagaatttt aacaatattt tgctaaagag
    44341 aaagattgtt ttactacttc gtatagttct gatgatgatt ttgataaacc atctattgtc
    44401 aacagcggtt caaaagcagg atgctgttat ctttttcaag agagaattga tttcaatttt
    44461 ttcctataat gactattctg aagcgaattt agaaatcccc aaactcttgt taaacctttc
    44521 gcttttcatg gtaggatggc tctctgtcat tttacttgaa agtgatttgg cagaccatta
    44581 ccatcacttg attcgctatc aatcaagctc ctttttcgat tatacaagga aacgattggt
    44641 tgtcatttct aaatttttta ctcaagattt gtttgtctgg tttcttggtt tacttcctct
    44701 aggaattcat ttcaaaacag tcgcactttt ctttttactt gctcagttaa tgatgttgta
    44761 cttactactg tcttatctga tagcactgat tagtgcgggc gctggttttt ccttttttct
    44821 ctatttttta gcatttgtgg gacaagaatg gatgatggat catattgtaa cagtgtattt
    44881 actactctta agtttattag ttatgttgat tgttagtcgc ttggaagaga aatttaagaa
    44941 aggataaacg atgagacttg aaattataaa tggacagaaa atttatggga aaagacctat
    45001 tttaaatcag ttgaatttgg tgtttcaatc aggaaaaatt tatggactta aaggtgataa
    45061 tggatctggc aagacggttc ttttaaagat acttgctggt tatattaagc ttgacaaagg
    45121 aaaagttctt caagatggta aagtttacgg ggtaaaaaat cattatattc aggatgcagg
    45181 aattttaatt gaaaaagtcg agtttttatc tcatttatcc ctgagagaaa atttggaact
    45241 gttaaggtat ttttcatcta aagttacgga aaaaagaatt gcctattgga ttcaatacta
    45301 tgatttacag gaatttgaag acattgaata ccgtcattta tccttaggaa caaagcaaaa
    45361 aatggccttg attcaagcct ttatttcctc tccttctata ctctttctcg atgaacctat
    45421 gaatgctttg gatgagaaga gtgtgaggtt aaccaaacag gtcattttat cttacctgaa
    45481 aaaagaaaat ggtctggtta tcctgacgtc gcacatatcg gaagatattt cagacctttg
    45541 tacagatgta ttagttgtcg aaaatggaca tatacaaatg taaaggatat acaatcctag
    45601 gagatggctt atggcacatc taaaatcatt tattacacgc tattccaagg tttatattgg
    45661 tttagttctg ctgatctggc tgtctttctt ctttcttcct tggggcagtc cgattctggg
    45721 ggggaagatt gacctcttca gcatacagaa agtcttgcta gtttttggca ttctgtccat
    45781 tttgatggcc ttgctgtcca agaaagtcag tctctttgtt tttggattga tctgctgtct
    45841 ttctctttgg attaacttat ttatcctatt tgctattttg ccgattcttg gcaattaaag
    45901 tatcataaaa gtcagagagg ttagcttgga aactaacctc tttttccttt tcaaaatggg
    45961 gattcttcct tgaaaataat cagtaattgt gctaaaatta aaggaacatt ctaaaatatt
    46021 cggaatttaa agtaaggaaa aacatggcta atattttaaa aacaattatc gaaaatgata
    46081 aaggagaaat ccgtcgtctg gaaaagatgg ctgacaaggt tttcaaatac gaagaccaaa
    46141 tggctgcttt gactgacgac caactaaaag caaaaacagt tgaatttaag gaacgttatc
    46201 aaaatggaga atcactggat tcattgcttt acgaagcatt tgcggttgtc cgtgaaggtg
    46261 ccaaacgtgt cctaggtctc ttcccttata aggttcaggt catggggggg attgttcttc
    46321 accatggtga cgtgccagag atgcgtacag gggaagggaa aaccttgact gcgaccatgc
    46381 cggtatacct caatgccctt tcaggtaaag gggttcacgt agttacggtt aatgaatacc
    46441 tgtcagaacg tgacgcgact gagatgggtg aattgtactc ttggcttggt ttgtcagtag
    46501 ggattaactt ggctaccaaa tctccaatgg agaaaaaaga agcctatgag tgtgatatta
    46561 cttactcaac taactcagaa atcggatttg actaccttcg tgacaacatg gtcgttcgcg
    46621 ctgaaaacat ggtacaacgt ccgcttaact atgccttggt cgatgaggtt gactctatct
    46681 tgattgacga ggctcgtaca cctttgattg tatcaggtgc caatgcggtt gaaaccagtc
    46741 agttgtatca catggcagac cactatgtaa aatctttgaa caaagatgac tacatcatcg
    46801 atgtgcagtc taagactatt ggtttgtctg attcagggat tgacagggct gaaagctact
    46861 tcaaacttga aaacctctat gacatcgaaa acgtggcttt gacccacttt atcgataacg
    46921 cccttcgtgc caactacatc atgcttctcg atattgacta tgtggtgagc gaagagcaag
    46981 aaatcttgat tgtcgaccaa tttacaggtc gtaccatgga aggtcgtcgt tattctgatg
    47041 gattgcacca agctattgaa gccaaagaag gtgtgccaat ccaggatgaa accaagacat
    47101 ctgcctcaat cacgtaccaa aaccttttcc gtatgtacaa gaaattgtct ggtatgacgg
    47161 gtacaggtaa gactgaggaa gaagaattcc gtgaaatcta caacattcgt gttattccaa
    47221 tcccaacaaa ccgtcctgtt caacgtattg accactcaga ccttctttat gcaagtatag
    47281 aatctaagtt taaagcggtt gtcgaagacg ttaaggctcg ttaccaaaag ggtcaacctg
    47341 tcttggttgg tacagtagcg gttgaaacta gtgactacat ttctaagaaa ttggttgcag
    47401 ctggtgttcc tcacgaagtc ttgaatgcca aaaaccacta tagagaagcc caaatcatca
    47461 tgaatgctgg tcaacgtggt gccgttacca tcgcaaccaa catggcgggt cgtggtaccg
    47521 acatcaagct tggtgaaggt gttcgtgaac ttggaggact ttgtgttatt ggtacagaac
    47581 gtcatgaaag tcgtcgtatc gataaccagc ttcgtggacg ttcaggtcgt caaggagatc
    47641 caggtgagtc acaattctac ctatctcttg aagatgattt gatgaaacgt tttggttctg
    47701 aacgcttgaa gggaatcttt gaacgcttga acatgtctga agaggcgatt gagtctcgca
    47761 tgttgacgcg tcaggttgaa gcagctcaga aacgtgtcga aggaaataac tacgataccc
    47821 gtaaacaagt ccttcaatac gacgatgtca tgcgtgaaca acgtgagatt atctatactc
    47881 aacgttatga tgtcattact gcagaccgtg acttggcacc tgaaattcag tctatgatca
    47941 aacgcacgat tgaacgtgtc gttgatggtc atgcgcgtgc caaacaagat gaaaaactag
    48001 aggcaatttt gaactttgct aagtacaact tgcttcctga agattctatt acgatggaag
    48061 acttgtcagg cttgtctgat aaggccatca aggaagagct tttccaacgt gccttgaagg
    48121 tttacgatag tcaggtttca aaactacgcg atgaagaagc agttaaagaa ttccaaaaag
    48181 ttttgattct acgagtggtg gataacaagt ggacagatca tatcgatgcc cttgatcaat
    48241 tgcgtaacgc ggttggactt cgtggctatg ctcagaacaa ccctgttgtt gagtatcagg
    48301 cagaaggttt ccgtatgttt aatgatatga ttggttcgat tgagtttgat gtgacacgct
    48361 tgatgatgaa agcacaaatt catgaacaag aaagaccaca ggcagaacgt catatcagta
    48421 caacagcgac tcgcaatatc gctgctcacc aagcaagtat gccagaagat ttggatttga
    48481 gccagattgg acgcaatgaa ctttgcccat gtggttctgg taagaaattt aaaaactgtc
    48541 acggtaaaag acaataaaat gagatagttt agaggcggat atcttgtgaa aagtaaattt
    48601 ttactgggta tccgtttgct ttataaggag atgagttatg gtatttacag caaaaagctc
    48661 taaaataaat atagaagaag ttcgtgcctt gtcaaaatta gaaggtcagg ctttggagag
    48721 gaaatcacag cgagatcaag agctagaagc cattatacgt ggagaagacc agcgaattct
    48781 cttggtaatc gggccatgct catctgacaa cgaagaagct gtccttgaat acgctaagcg
    48841 tttggcagtc ctacaagaag aagtggcaga tcgtatcttt atggttatgc gtgtttatac
    48901 tgccaaaccc cgtaccaacg gagatggcta taagggcttg attcaccagc ctaacgcgac
    48961 agaagcgcct agtcttatca atggaatcaa agccgttcgc catcttcact atcgtgtcat
    49021 cacagaaaca gggatgacaa ctgctgatga aatgctttat cctgaaaacc ttccgcttgt
    49081 agatgatttg atttcttaca tggcagttgg tgcccgttca gttgaagacc agcaacaccg
    49141 ctttgtggca agtggggcag gattttctac tggttttaaa aatccaacct ctggaaatct
    49201 caatgtcatg tttaatggga tttatgctgc tcaaaacaaa caaagtttcc ttttcttagg
    49261 aaaagaagta gaaacaactg ggaacccgct ttcacacgct attcttcgtg gtgctcttaa
    49321 tgagtatgga aaaaatattc ccaactacta ttatgacaat ttaattgata ccattgccca
    49381 gtatgagaaa atgggcttgg aaaatccttt tatcatcatt gataccaatc atgacaattc
    49441 tggtaagcag tatattgaac agatccgaat tgtccgccag accttgatta accgtgcttg
    49501 gaatgaaaaa attaagcagt tcgttcgtgg ttttatgatt gagtcttatc tggaagatgg
    49561 tcgacaaaat gagccagaag tatttggtaa gtctatcaca gacccttgcc tgggttggga
    49621 taacacagaa gctcttgtca gagaaattta caaaacgtta ggagaataag atggcattta
    49681 ttgaaaaagg tcaagaaatc gatatggaag tcatcaaggc tgaaacccaa ttgtctgcgg
    49741 aagccttgag actcaaggaa agccgtgaca gggaattggc agatattatt tcaggggaag
    49801 atgaccgtat tctcttggtg attggtcctt gctcttctga taatgaagag gcggtcttgg
    49861 aatatgctcg ccgtttatcc gccttgcaaa agaaggtagc ggataagatt ttcatggtca
    49921 tgcgcgtgta tactgctaag cctcgtacca atggagacgg ctataaagga ttagttcacc
    49981 agccagatac ttctaaggct ccaagcctga ttaatggctt gcaggctgtg cgccagttgc
    50041 actaccgcgt gattacagag actggtttga caacggcaga tgagatgctt tatccgtcaa
    50101 atctgatctt ggtggatgac ttggtcagct accatgccgt tggagctcgt tctgtggaag
    50161 accaagagca ccgctttgtg gcttctggga ttgatgcacc agtagggatg aaaaatccaa
    50221 cctcaggaaa tttgggtgtt atgtttaacg ccatctatgc tgctcaaaac aagcaaacct
    50281 tcctttatca tgggcaggaa gttgagacat caggtaatcc tttggcccat gttatcctcc
    50341 gtggagcagt caacgagtat ggcaattata tgccgaatta ctactatgaa aacctactcc
    50401 aagccattga acgctatgaa accatgggac ttgaaaatcc ttttatcctc attgacacca
    50461 accatgataa ctcaggcaag caatatatgg agcagattcg aattgttcgc cagaccttgc
    50521 agaatcgtga ttggaatgag aaaattaaaa agacggttcg aggatttatg attgaatctt
    50581 acctagcaga tggtcgtcaa aaccaaccag agatctttgg ttgctctatt actgaccctt
    50641 gcctaggttg ggaaaataca gaggccttgg tagaagagat ttatgttacc ttgacaaaat
    50701 aagtgaaaag gatggagttg gggaatctca actccttttg atgagaatga tagttggaca
    50761 cggaattgac atcgaagaat tggcttcgat agaaagcgca gttacacgac atgaaggatt
    50821 tgctaagcgt gtactgaccg ctcaggaaat ggagcgcttc accagtctca aaggacgcag
    50881 gcaaatagaa tatttagctg gtcgctggtc ggctaaggag gccttttcca aggctatggg
    50941 aacgggcatt agcaagctcg gttttcagga tttggaagtc ttgaacaatg aacgtggggc
    51001 gccttatttt agtcaggcac cattttcagg aaagatttgg ctgtctatca gccacaccga
    51061 tcagtttgtg acagccagtg tcattttgga ggaaaatcat gaaagctagt ccacatagac
    51121 caaccaaggc tctgattcat ctgggagcta ttcgacaaaa tattcagcaa atgggggctc
    51181 atatccctca aggaacgctc aagttggctg tggttaaggc caatgcttat ggtcatggag
    51241 ctgttgccgt tgccaaggca attcaagatg atgttgatgg cttttgcgtt tccaatatcg
    51301 atgaagccat tgaactcaga caagctggac tcagcaagcc aatcctcatt ttaggagttt
    51361 ctgaaatcga agctgttgct ctagctaaag aatatgactt caccttgaca gtggctggac
    51421 tggagtggat tcaagcactc ttagataagg aagtggacct aactggattg acagtccacc
    51481 tcaagattga ttcagggatg ggacggattg gttttagaga ggccagtgag gttgagcagg
    51541 ctcaagattt gctccaacaa cacggtgttc gtgttgttgg aatctttacc cactttgcta
    51601 ctgctgatga ggaatcagat gactatttta atgcccagtt agaacggttt aaaactattt
    51661 tagctagtat gaaggaagtt ccagagctgg ttcatgctag caattctgca acgactcttt
    51721 ggcatgtaga gactattttc aatgcggttc gtatgggaga tgccatgtat ggtctcaatc
    51781 caagtggagc ggtcttggat ttgccttatg atttgatacc ggccttgacc ttggagtctg
    51841 ctctggttca tataaagaca gttccagctg gagcttgcat gggctatgga gcaacttatc
    51901 aagcggatag cgagcaagtc atcgcgaccg tgccaatcgg gtatgcagat ggatggacaa
    51961 gagacatgca aaatttctct gtcttggtag atggccaagc ttgcccaatt gttggcaggg
    52021 tttcgatgga ccaaatcact attcgattgc ctaagcctta cccactcgga accaaggtaa
    52081 ccttgattgg ctccaatggg gataaggaaa tcactgcaac tcaggtagcg acctaccgcg
    52141 taaccattaa ctatgaggtg gtttgcctcc tcagcgaccg tattccgaga gaatattatt
    52201 agaaaagaaa ggagtggagc atgaatctac atcaaccctt gcatgtcttg cctggtgtgg
    52261 gaccaaagtc agcagaaaaa tacgccaaac taggaattga aaacttgcaa gatctcttgc
    52321 tctactttcc tttccgttat gaagacttca aaaccaagca ggtgctggag ctggaagacg
    52381 gtgagaaggc agttctttct ggtcaggtag tgactcctgc tagtgtccag tattatggtt
    52441 tcaagcgcaa tcgcctgcgt tttagtctca agcagggaga ggtcgttttt gcggtgaatt
    52501 tctttaacca gccctatctg gctgataaaa tagagttggg agcaaccctt gctgtctttg
    52561 gaaaatggga ccgcgctaag gctagtctga ctgggatgaa ggttctggct caggtagaag
    52621 atgacctcca gcctgtttat cgtctggctc agggaatcag tcaggccagt ctggttaagg
    52681 tcatcaagac ggcttttgat cagggactgg acctcttgat agaagaaaat ctgccccagt
    52741 ctttactaga caaatacaaa ctcatgtccc gttgtcaggc agtccgagct atgcattttc
    52801 caaaggattt ggcagaatac aagcaggctc ttcgccgtat aaagtttgag gaactctttt
    52861 atttccaaat gcagctgcag acgctcaagt ctgaaaatag aattcaggga agtggtctgg
    52921 ttctggattg gtctcaggaa aaagtgacag cagttaaagc aagtcttcct tttgccctga
    52981 cccaagctca ggaaaagagt ttgcaggaaa ttttaactga tatgaagtcc gaccaccaca
    53041 tgaatcgtct cctacaaggg gatgtgggga gtggaaaaac ggtagtcgct ggcttggcca
    53101 tgtttgcggc agtgacagca ggttatcagg ctgccctaat ggtaccaaca gaaatcctcg
    53161 cagagcaaca ctttgagagt ttacagaacc tttttcccaa tttgaaactg gctctcttga
    53221 caggttcctt gaaagctgca gaaaagagag aagtcttgga gaccattgtc aagggtgagg
    53281 ctgatttgat tataggaact cacgctctga tacaagatgg ggtggagtat gctcgtcttg
    53341 gtttgattat tatcgatgag cagcaccgtt ttggtgtagg gcaaaggcgt attttacggg
    53401 aaaaaggtga caatccagat gtcctcatga tgacggcgac tcccattcca cggacgcttg
    53461 ccatcacagc ctttggagat atggatgttt ccattatcga ccagatgcca gcaggtcgga
    53521 agcctattgt gacgcgctgg atcaaacatg agcaactacc tcaggtcttg acttggttag
    53581 agggggaaat tcaaaaaggt tcccaagcct atgtcatctc tcctttgatt gaagaatcag
    53641 aagctctaga tttgaaaaat gccattgcct tatcagagga gttgacgact cattttgcag
    53701 gcaaggcaga ggtggctctt ctacatggta ggatgaagag tgacgaaaaa gaccagatca
    53761 tgcaggattt caaggagaga aagacggata ttctggtttc gacgacggtt attgaggttg
    53821 gggtcaacgt tcccaatgcg actgtcatga ttatcatgga tgccgatcgc ttcggtctca
    53881 gtcaacttca ccagcttaga ggtcgtgtcg gtcgggggga caagcagtcc tacgctgttc
    53941 tcgttgccaa tcccaagacg gattctggga aagaccgcat gcgcatcatg acagaaacga
    54001 ccaatggatt tgtccttgcg gaggaagatt tgaaaatgcg tggttctggt gagatttttg
    54061 gaaccagaca gtcaggactt ccagagttcc aagtggctga tattatcgaa gattttccga
    54121 ttttagaaga agcaagaaag gttgctagct acattagttc tatagaagct tggcaagaag
    54181 atccagagtg gcgcatgatt gcccttcatc tggaaaagaa agaacatctg gattaagctt
    54241 tctctaagga aaacttaagc tagtttttag gtttggctct tatactaaag tcatcaaaaa
    54301 gaaacgagga ctctcatatg acagtaacga ttaaagtaaa ttaccaaacc actttccaaa
    54361 agaaggaagc aaaaaactag tataaacaga agagagagcg aaatgctctt tttcgtttct
    54421 aaaactactt tcagcccatc atcctaaaag taaagaatct aaattcactt tctatttatc
    54481 cttctttctt gcattgatta catagatatg ctacagttgt ggtaacgatt acaaaataaa
    54541 aggagcatgc tatgaaaaat ccagctttgc tagaagaaat taagacctat agaggaaggg
    54601 atgaggttcc ggaagacttt gatgctttct gggatgggga agtgaaaaat gtttccacac
    54661 ctccatccta ccacttggag gaaagagatt tccacattcc tcaagtcaag tgctatgagt
    54721 taacatttga aggaagcaag gaaggaaagg tctatgcacg cattgttctt ccaaagagtg
    54781 aggagaaggt tccactaatc ttccattttc atggttatat gggacgtggc tgggactggg
    54841 ccgacatgct gggcttcacc gtagctggtt atggtgttgt ttccatggat gtgcggggcc
    54901 agtcaggtta ctcacaagac ggcttgcgtt ctcctttagg aaataccgtg aaggggcata
    54961 ttatccgtgg tgctatggaa ggtcgggacc acctctttta taaggatgtt tatctggata
    55021 tttaccagtt ggtcgaaatt gttgctagtc tgtctcaggt tgatgagaag cgtctttcta
    55081 gctatggtgc ctcacaagga ggggctctag ctctagttgc agcagcgctc aatcctcgaa
    55141 ttcagaaaac agttgccatt tatcccttct tgtcagactt cagacgggtg attgagattg
    55201 gtaatactag cgaggcttac gacgaacttt tccgttattt caagtttcac gaccccttcc
    55261 atgaaacaga ggaggaaatc atggcgaccc ttgcctatat cgatgtcaaa aatcttgccc
    55321 atcgtatcca aggtgaggtt aagatgatta cgggcttgga cgacgatgtt tgctatccca
    55381 ttacccagtt tgcgatttat aatcgtctga cctgcgataa aacctatcgc atcatgcctg
    55441 agtatgctca cgaagccatg aatgtatttg tcgatgacca agtctacaac tggctctgtg
    55501 ggagtgagat tccttttaaa tatctaaaat aaggagtcga ctctaagcac aaaatcttaa
    55561 aaattacaaa tacgcatagt atcaggggat taagaaaact tgatactatg cgttttatca
    55621 tggaaatata gtaaaatgaa ataaaaacag gacaaatcga tcaggacagt caaatcgatt
    55681 tctaacaatg ttttagaagc aaaggtgtac tattctagtt tcaatctatt gtatttataa
    55741 aattttttgt tgctagattt gtcaaattgc ttaaaataat ttttttcaga aagcaaaagc
    55801 cgatacctat cgagtagggt agttcttgct atcgtcaggc ttgtctgtag gtgttaatac
    55861 ttttcaaaaa tctcttcaaa ccacgtcagc ttcgccttgc cgtatatatg ttactgactt
    55921 cgtcagttct atctgccacc tcaaaacggt gttttgagct gacttcgtca gttctatctg
    55981 ccacctcaaa acggtgtttt gagctgactt tgtcagtctt atctaccacc tcaaaacagt
    56041 gttttgagct gacttcgtca gtcttatcta ccacctcaaa acagtgtttt gagcatcatg
    56101 cggctagctt cttagtttgc tctttgattt tcattgagta taaaaacaga tgagtttctg
    56161 ttttcttttt atggactata aatgttcagc tgaaactact ttcaaggaca ttattatata
    56221 aaagaatttt ttgaaactaa aatctactat attacactat attgaaagcg ttttaaaaat
    56281 gaggtataat aaatttacta acacttataa aaagtgatag aatctatctt tatgtatatt
    56341 taaagataga ttgctgtaaa aatagtagta gctatgcgaa ataacagata gagagaaggg
    56401 attgaagctt agaaaagggg aataatatga tatttaaggc attcaagaca aaaaagcaga
    56461 gaaaaagaca agttgaacta cttttgacag tttttttcga cagttttctg attgatttat
    56521 ttcttcactt atttgggatt gtccccttta agctggataa gattctgatt gtgagcttga
    56581 ttatatttcc cattatttct acaagtattt atgcttatga aaagctattt gaaaaagtgt
    56641 tcgataagga ttgagcagga agtatggtgt aaatagcata ggctgatgtc catcatttgc
    56701 ttataaagag atattttagt ttaattgcag cggtgtcctg gtagataaac tagattggca
    56761 ggagtctgat tggagaaagg agaggggaaa attggcacca atttgagata gtttgtttag
    56821 ttcatttttg tcatttaaat gaactgtagt aaaagaaagt taataaaaga caaactaagt
    56881 gcattttctg gagtaaatgt cttatttcag aaatcgggat atagatatag agaggatcag
    56941 tatgaatcgg agtgttcaag aacgtaagtg tcgttatagc attaggaaac tatcggtagg
    57001 agcggtttct atgattgtag gagcagtggt atttggaacg tctcctgttt tagctcaaga
    57061 aggggcaagt gagcaacctc tggcaaatga aactcaactt tcgggggaga gctcaaccct
    57121 aactgataca gaaaagagcc agccttcttc agagactgaa ctttctggca ataagcaaga
    57181 acaagaaagg aaagataagc aagaagaaaa aattccaaga gattactatg cacgagattt
    57241 ggaaaatgtc gaaacagtga tagaaaaaga agatgttgaa accaatgctt caaatggtca
    57301 gagagttgat ttatcaagtg aactagataa actaaagaaa cttgaaaacg caacagttca
    57361 catggagttt aagccagatg ccaaggcccc agcattctat aatctctttt ctgtgtcaag
    57421 tgctactaaa aaagatgagt acttcactat ggcagtttac aataatactg ctactctaga
    57481 ggggcgtggt tcggatggga aacagtttta caataattac aacgatgcac ccttaaaagt
    57541 taaaccaggt cagtggaatt ctgtgacttt cacagttgaa aaaccgacag cagaactacc
    57601 taaaggccga gtgcgcctct acgtaaacgg ggtattatct cgaacaagtc tgagatctgg
    57661 caatttcatt aaagatatgc cagatgtaac gcatgtgcaa atcggagcaa ccaagcgtgc
    57721 caacaatacg gtttgggggt caaatctaca gattcggaat ctcactgtgt ataatcgtgc
    57781 tttaacacca gaagaggtac aaaaacgtag tcaacttttt aaacgctcag atttagaaaa
    57841 aaaactacct gaaggagcgg ctttaacaga gaaaacggac atattcgaaa gcgggcgtaa
    57901 cggtaactca aataaagatg gaatcaagag ttatcgtatt ccagcacttc tcaagacaga
    57961 taaaggaact ttgatcgcag gtgcagatga acgccgtctc cattcgagtg actggggtga
    58021 tatcggtatg gtcatcagac gtagtgaaga taatggtaaa acttggggtg accgagtaac
    58081 cattaccaac ttacgtgaca atccaaaagc ttctgaccca tcgatcggtt caccagtgaa
    58141 tatcgatatg gtgttggttc aagatcctga aaccaaacga atcttttcta tctatgacat
    58201 gttcccagaa gggaagggaa tctttggaat gtcttcacaa aaagaagaag cctacaaaaa
    58261 aatcgatgga aaaacctatc aaatcctcta ccgtgaagga gaaaagggag cttataccat
    58321 tcgagaaaat ggtactgtct atacaccaga tggtaaggcg acagactatc gcgttgttgt
    58381 agatcctgtt aaaccagcct atagcgacaa gggtgatcta tacaagggta accaattact
    58441 aggcaatatc tacttcacaa caaacaaaac ttctccattt agaattgcca aggatagcta
    58501 tctatggatg tcctacagtg atgacgacgg gaagacatgg tcagcgcctc aagatattac
    58561 tccgatggtc aaagccgatt ggatgaaatt cttgggtgta ggtcctggaa caggaattgt
    58621 acttcggaat gggcctcaca agggacggat tttgatacca gtttatacga ctaataatgt
    58681 atctcactta aatggctcgc aatcttctcg tgtcatctat tcagatgatc atggaaaaac
    58741 ttggcatgct ggagaagcgg tcaacgataa ccgtcaggta gacggtcaaa agatccactc
    58801 ttctacgatg aacaatagac gtgcgcaaaa tacagaatca acggtggtac aactaaacaa
    58861 tggagatgtt aaactcttta tgcgtggttt gactggagat cttcaggttg ctacaagtaa
    58921 agacggagga gtgacttggg agaaggatat caaacgttat ccacaggtta aagatgtcta
    58981 tgttcaaatg tctgctatcc atacgatgca taatggaaaa gaatacatta tcctcagcaa
    59041 tgcaggtgga ccgaatcgtg aaaatgggat ggtccacttg gcacgtgtcg aagaaaatgg
    59101 tgagttgact tggctcaaac acaatccaat tcaaaaagga gagtttgcct ataattcgct
    59161 ccaagaatta ggaaatgggg agtatggcat cttgtatgaa catactgaaa aaggacaaaa
    59221 tgcctatacc ctatcattta gaaaatttaa ttgggacttt ttgagcaaag atctgatttt
    59281 tcctaccgaa gcgaaagtga agcgaactag agagatgggc aaaggagaga tgggcaaagg
    59341 agttattggc ttggagttcg actcagaagt attggtcaac aaggctccaa cccttcaatt
    59401 ggcaaatggt aaaacagcga ctttcctaac ccagtatgat agcaagacct tgttgtttgc
    59461 agtagataag gaagatatcg gacaggaaat tattggtata gctaaaggaa gcatcgaaag
    59521 tatgcataat cttcctgtaa atctagcagg tgccagagtt cctggcggag taaatggtag
    59581 caaagcagcg gtgcatgaag ttccagaatt tacaggggga gttaatggta cagagccagc
    59641 tgttcataaa atcgcagagt ataagggatc tgattcgctt gtaactctta ctacaaaaga
    59701 agattatact tacaaagctc ctcttgctca gcaggcactt cctgaaacag gaaacaagga
    59761 gagtgacctc ctagcttcac taggactaac agctttcttc cttggtctgt ttacgctagg
    59821 gaaaaagaga gaacaataag agaagaattc taaacatttg attttgtaaa aatagaagga
    59881 gatagcaggt tttcaagcct gctatctttt tttgatgaca ttcaagctga tacgaaatca
    59941 taagaggtct gaaactactt tcagagtagt ctgttctata aaatatagta gattgaaata
    60001 agatgtgaac aactct
//
LOCUS       DAVMAH010000004        58587 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVMAH010000004 DAVMAH010000000
VERSION     DAVMAH010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.004"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            53..826
                     /locus_tag="VYO94_000174"
     CDS             53..826
                     /locus_tag="VYO94_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000878698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1758878.1"
                     /translation="MLAACSGGAKKEGQAASKKEIIVATNSSPKPFNYEENGELTGYE
                     IEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAVNNISYTKERAEKYLYAAPT
                     VKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQLEDYNKQHSDNPTILNYTKA
                     NLQQIMGHLSDGQFDYKIFDKITVETVIKNQGLDNLKVIDLPSDQQPYVYPLLAKGQD
                     ELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK"
     gene            867..944
                     /locus_tag="VYO94_000175"
                     /pseudo
     CDS             867..944
                     /locus_tag="VYO94_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            1047..1877
                     /locus_tag="VYO94_000176"
     CDS             1047..1877
                     /locus_tag="VYO94_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1758879.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2031..2885
                     /locus_tag="VYO94_000177"
     CDS             2031..2885
                     /locus_tag="VYO94_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1758880.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            2985..4358
                     /locus_tag="VYO94_000178"
     CDS             2985..4358
                     /locus_tag="VYO94_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV1758881.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMTFLKRFFFDLALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4351..5412
                     /locus_tag="VYO94_000179"
     CDS             4351..5412
                     /locus_tag="VYO94_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV1758882.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5414..6106
                     /locus_tag="VYO94_000180"
     CDS             5414..6106
                     /locus_tag="VYO94_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1758883.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6136..6705)
                     /locus_tag="VYO94_000181"
     CDS             complement(6136..6705)
                     /locus_tag="VYO94_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1758884.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAQLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            6840..7454
                     /locus_tag="VYO94_000182"
     CDS             6840..7454
                     /locus_tag="VYO94_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1758885.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLVGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7456..9102
                     /locus_tag="VYO94_000183"
     CDS             7456..9102
                     /locus_tag="VYO94_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1758886.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPVGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMVVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9114..10400
                     /locus_tag="VYO94_000184"
     CDS             9114..10400
                     /locus_tag="VYO94_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1758887.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGHPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVSITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10452..10985
                     /locus_tag="VYO94_000185"
     CDS             10452..10985
                     /locus_tag="VYO94_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1758888.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11063..11533
                     /gene="nrdI"
                     /locus_tag="VYO94_000186"
     CDS             11063..11533
                     /gene="nrdI"
                     /locus_tag="VYO94_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV1758889.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(11826..13088)
                     /locus_tag="VYO94_000187"
     CDS             complement(11826..13088)
                     /locus_tag="VYO94_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV1758890.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13398..13856)
                     /locus_tag="VYO94_000188"
     CDS             complement(13398..13856)
                     /locus_tag="VYO94_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV1758891.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(13853..14293)
                     /locus_tag="VYO94_000189"
     CDS             complement(13853..14293)
                     /locus_tag="VYO94_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1758892.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKSDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVPKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14649..16598
                     /gene="mutL"
                     /locus_tag="VYO94_000190"
     CDS             14649..16598
                     /gene="mutL"
                     /locus_tag="VYO94_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV1758893.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(16923..17390)
                     /locus_tag="VYO94_000191"
     CDS             complement(16923..17390)
                     /locus_tag="VYO94_000191"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV1758894.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17391..18596)
                     /locus_tag="VYO94_000192"
     CDS             complement(17391..18596)
                     /locus_tag="VYO94_000192"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV1758895.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18616..19251)
                     /gene="ribE"
                     /locus_tag="VYO94_000193"
     CDS             complement(18616..19251)
                     /gene="ribE"
                     /locus_tag="VYO94_000193"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV1758896.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19236..20336)
                     /gene="ribD"
                     /locus_tag="VYO94_000194"
     CDS             complement(19236..20336)
                     /gene="ribD"
                     /locus_tag="VYO94_000194"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV1758897.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20470..20584)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            20741..21334
                     /gene="ruvA"
                     /locus_tag="VYO94_000195"
     CDS             20741..21334
                     /gene="ruvA"
                     /locus_tag="VYO94_000195"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV1758898.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21344..21907
                     /locus_tag="VYO94_000196"
     CDS             21344..21907
                     /locus_tag="VYO94_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV1758899.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKIVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            21904..22581
                     /locus_tag="VYO94_000197"
     CDS             21904..22581
                     /locus_tag="VYO94_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1758900.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(22736..23767)
                     /locus_tag="VYO94_000198"
     CDS             complement(22736..23767)
                     /locus_tag="VYO94_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV1758901.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDNNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(24022..24705)
                     /locus_tag="VYO94_000199"
     CDS             complement(24022..24705)
                     /locus_tag="VYO94_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV1758902.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24717..25661)
                     /locus_tag="VYO94_000200"
     CDS             complement(24717..25661)
                     /locus_tag="VYO94_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1758903.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            25793..28624
                     /gene="uvrA"
                     /locus_tag="VYO94_000201"
     CDS             25793..28624
                     /gene="uvrA"
                     /locus_tag="VYO94_000201"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV1758904.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAITQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28617..29678
                     /locus_tag="VYO94_000202"
     CDS             28617..29678
                     /locus_tag="VYO94_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1758905.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLTQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            29810..30208
                     /gene="spx"
                     /locus_tag="VYO94_000203"
     CDS             29810..30208
                     /gene="spx"
                     /locus_tag="VYO94_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV1758906.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30274..30843
                     /locus_tag="VYO94_000204"
     CDS             30274..30843
                     /locus_tag="VYO94_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1758907.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSNYISDRLANGATEQ"
     gene            30930..31196
                     /locus_tag="VYO94_000205"
     CDS             30930..31196
                     /locus_tag="VYO94_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV1758908.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31200..31619
                     /gene="ruvX"
                     /locus_tag="VYO94_000206"
     CDS             31200..31619
                     /gene="ruvX"
                     /locus_tag="VYO94_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV1758909.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31635..31940
                     /locus_tag="VYO94_000207"
     CDS             31635..31940
                     /locus_tag="VYO94_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV1758910.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32195..33445
                     /locus_tag="VYO94_000208"
     CDS             32195..33445
                     /locus_tag="VYO94_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1758911.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33442..33987
                     /locus_tag="VYO94_000209"
     CDS             33442..33987
                     /locus_tag="VYO94_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV1758912.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDID
                     GTYTGRDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVN
                     GNQIVVDDMDRDPSDQIVLTK"
     gene            34133..35665
                     /gene="cls"
                     /locus_tag="VYO94_000210"
     CDS             34133..35665
                     /gene="cls"
                     /locus_tag="VYO94_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV1758913.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            35743..35886
                     /locus_tag="VYO94_000211"
     CDS             35743..35886
                     /locus_tag="VYO94_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758914.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            35923..37461
                     /locus_tag="VYO94_000212"
     CDS             35923..37461
                     /locus_tag="VYO94_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1758915.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFVHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37581..39788
                     /gene="nrdD"
                     /locus_tag="VYO94_000213"
     CDS             37581..39788
                     /gene="nrdD"
                     /locus_tag="VYO94_000213"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV1758916.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            39800..39940
                     /locus_tag="VYO94_000214"
     CDS             39800..39940
                     /locus_tag="VYO94_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758917.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            39984..40490
                     /locus_tag="VYO94_000215"
     CDS             39984..40490
                     /locus_tag="VYO94_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1758918.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPANRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            40483..41073
                     /gene="nrdG"
                     /locus_tag="VYO94_000216"
     CDS             40483..41073
                     /gene="nrdG"
                     /locus_tag="VYO94_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV1758919.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41070..41687
                     /locus_tag="VYO94_000217"
     CDS             41070..41687
                     /locus_tag="VYO94_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV1758920.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            41954..42262
                     /gene="rpsJ"
                     /locus_tag="VYO94_000218"
     CDS             41954..42262
                     /gene="rpsJ"
                     /locus_tag="VYO94_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV1758921.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42478..43104
                     /gene="rplC"
                     /locus_tag="VYO94_000219"
     CDS             42478..43104
                     /gene="rplC"
                     /locus_tag="VYO94_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV1758922.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43129..43752
                     /gene="rplD"
                     /locus_tag="VYO94_000220"
     CDS             43129..43752
                     /gene="rplD"
                     /locus_tag="VYO94_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV1758923.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            43752..44048
                     /locus_tag="VYO94_000221"
     CDS             43752..44048
                     /locus_tag="VYO94_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV1758924.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44066..44899
                     /gene="rplB"
                     /locus_tag="VYO94_000222"
     CDS             44066..44899
                     /gene="rplB"
                     /locus_tag="VYO94_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV1758925.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            44991..45272
                     /gene="rpsS"
                     /locus_tag="VYO94_000223"
     CDS             44991..45272
                     /gene="rpsS"
                     /locus_tag="VYO94_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV1758926.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45284..45628
                     /gene="rplV"
                     /locus_tag="VYO94_000224"
     CDS             45284..45628
                     /gene="rplV"
                     /locus_tag="VYO94_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV1758927.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            45641..46294
                     /gene="rpsC"
                     /locus_tag="VYO94_000225"
     CDS             45641..46294
                     /gene="rpsC"
                     /locus_tag="VYO94_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV1758928.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46298..46711
                     /gene="rplP"
                     /locus_tag="VYO94_000226"
     CDS             46298..46711
                     /gene="rplP"
                     /locus_tag="VYO94_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV1758929.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            46721..46927
                     /locus_tag="VYO94_000227"
     CDS             46721..46927
                     /locus_tag="VYO94_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV1758930.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            46952..47212
                     /gene="rpsQ"
                     /locus_tag="VYO94_000228"
     CDS             46952..47212
                     /gene="rpsQ"
                     /locus_tag="VYO94_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV1758931.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47238..47606
                     /gene="rplN"
                     /locus_tag="VYO94_000229"
     CDS             47238..47606
                     /gene="rplN"
                     /locus_tag="VYO94_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV1758932.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            47684..47989
                     /gene="rplX"
                     /locus_tag="VYO94_000230"
     CDS             47684..47989
                     /gene="rplX"
                     /locus_tag="VYO94_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV1758933.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48013..48555
                     /gene="rplE"
                     /locus_tag="VYO94_000231"
     CDS             48013..48555
                     /gene="rplE"
                     /locus_tag="VYO94_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV1758934.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48573..48842
                     /gene="rpsN"
                     /locus_tag="VYO94_000232"
     CDS             48573..48842
                     /gene="rpsN"
                     /locus_tag="VYO94_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV1758935.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49056..49454
                     /gene="rpsH"
                     /locus_tag="VYO94_000233"
     CDS             49056..49454
                     /gene="rpsH"
                     /locus_tag="VYO94_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV1758936.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            49646..50182
                     /gene="rplF"
                     /locus_tag="VYO94_000234"
     CDS             49646..50182
                     /gene="rplF"
                     /locus_tag="VYO94_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV1758937.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50266..50622
                     /gene="rplR"
                     /locus_tag="VYO94_000235"
     CDS             50266..50622
                     /gene="rplR"
                     /locus_tag="VYO94_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV1758938.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            50640..51134
                     /gene="rpsE"
                     /locus_tag="VYO94_000236"
     CDS             50640..51134
                     /gene="rpsE"
                     /locus_tag="VYO94_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV1758939.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51106..51330
                     /gene="rpmD"
                     /locus_tag="VYO94_000237"
     CDS             51106..51330
                     /gene="rpmD"
                     /locus_tag="VYO94_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV1758940.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            51475..51915
                     /gene="rplO"
                     /locus_tag="VYO94_000238"
     CDS             51475..51915
                     /gene="rplO"
                     /locus_tag="VYO94_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV1758941.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            51928..53238
                     /gene="secY"
                     /locus_tag="VYO94_000239"
     CDS             51928..53238
                     /gene="secY"
                     /locus_tag="VYO94_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV1758942.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53389..54027
                     /locus_tag="VYO94_000240"
     CDS             53389..54027
                     /locus_tag="VYO94_000240"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV1758943.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54144..54362
                     /gene="infA"
                     /locus_tag="VYO94_000241"
     CDS             54144..54362
                     /gene="infA"
                     /locus_tag="VYO94_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV1758944.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54387..54503
                     /gene="rpmJ"
                     /locus_tag="VYO94_000242"
     CDS             54387..54503
                     /gene="rpmJ"
                     /locus_tag="VYO94_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV1758945.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54521..54886
                     /gene="rpsM"
                     /locus_tag="VYO94_000243"
     CDS             54521..54886
                     /gene="rpsM"
                     /locus_tag="VYO94_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV1758946.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            54904..55287
                     /gene="rpsK"
                     /locus_tag="VYO94_000244"
     CDS             54904..55287
                     /gene="rpsK"
                     /locus_tag="VYO94_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV1758947.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55330..56265
                     /locus_tag="VYO94_000245"
     CDS             55330..56265
                     /locus_tag="VYO94_000245"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV1758948.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDNRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56277..56663
                     /gene="rplQ"
                     /locus_tag="VYO94_000246"
     CDS             56277..56663
                     /gene="rplQ"
                     /locus_tag="VYO94_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV1758949.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            56928..57194
                     /locus_tag="VYO94_000247"
     CDS             56928..57194
                     /locus_tag="VYO94_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV1758950.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57204..58541
                     /locus_tag="VYO94_000248"
     CDS             57204..58541
                     /locus_tag="VYO94_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV1758951.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGKEGDMIEFGGLLGTAPVMRVNGASSVDFISRGGQIPAPIHSFKN"
BASE COUNT        17656 a        11112 c        12970 g        16849 t
ORIGIN      
        1 aaaaatcgtt aaatactcat ctcttgctgc cctagggctt gttgctgcag gtgtgctagc
       61 agcttgctca ggtggtgcta agaaagaagg acaagcagct agcaagaaag aaattattgt
      121 tgcaactaat tcttcaccaa aaccattcaa ctatgaagaa aatggcgaat tgactggtta
      181 cgagattgaa gtcgttcgcg ctatctttaa agactctgac aagtatgatg tcaagtttga
      241 gaagacagag tggtcaggtg tctttgcggg tcttgacgct gaccgttacc aaatggctgt
      301 taacaatatc agctacacta aagaacgtgc ggagaaatac ctttatgcag ccccaactgt
      361 taaagaccct aacgttcttg tagtcaagaa agacgattct agcatcaaat cgcttgatga
      421 tgttggtgga aaatcaacag aagttgttca aggaacaaca tctgctaaac agttagaaga
      481 ctacaacaaa caacactcag ataatccaac tatccttaac tatactaaag caaacttaca
      541 acaaatcatg ggccacttga gcgatggtca gtttgactac aagatttttg ataaaatcac
      601 tgttgaaaca gtcatcaaga accaaggttt ggacaacttg aaagtcatcg atcttccaag
      661 cgaccaacaa ccgtacgttt acccacttct tgctaaaggt caagatgagt tgaaaacatt
      721 tgtagacaaa cgtatccaag aactctacaa agacggaact cttgaaaaat tgtctaaaca
      781 attcttcgga gacacttacc taccggcaga agctgatatt aaataatttc ttgaaatcat
      841 ccattctgag taagatgggt gatttttcag ttcgctaccg caatctagtc ggaacagttc
      901 tctttggagt ggtcttgatt gccatcttgc gtttggtctt ttaaattacc cataaaaaaa
      961 cttatcacag agatagatat catataatgg cgtaaatgct ctttttctgt taagattata
     1021 aggtattcta ttttggagga aatgacatga aaaaaatcgt taaatactca tctcttgctg
     1081 ccctaggact tgttgctgca ggtgtgcttg cggcttgctc agggggtgct aagaaagaag
     1141 gagaagcagc tagcaagaaa gaaatcatcg ttgcaaccaa tggatcacca aggccattta
     1201 tctatgaaga aaatggcgaa ttgactggtt acgagattga agtcgttcgc gctatcttta
     1261 aagattctga caaatataat gtcaagtttg aaaagacaga atggtcaggt gtctttgctg
     1321 gtcttgatgc tgaccgttat aatatggctg tcaacaatct tagctacact aaagaacgtg
     1381 cggagaaata cctctatgcc gcaccaattg cccaaaatcc taatgtcctt gtcgtgaaga
     1441 aagatgactc tagtatcaag tctctcgatg atatcggtgg aaaatcgacg gaagtcgttc
     1501 aagccactac atcagctaag cagttagaag catacaacgc tgaacacacg gacaacccaa
     1561 ctatccttaa ctatactaag gcagatttcc aacaaatcat ggtacgtttg agcgatggac
     1621 aatttgacta caagattttt gataaaatcg gtgttgaaac agtgatcaag aaccaaggtt
     1681 tggacaactt gaaagttatc gaacttccaa gcgaccaaca accgtacgtt tacccacttc
     1741 ttgctcaggg tcaagatgag ttgaaatcat ttgtagacaa acgcattaaa gaactctaca
     1801 aagacggaac gcttgaaaaa ttgtctaaac aattcttcgg agacacttat ctaccggcag
     1861 aagctgatat taaataattt cttgaaatca tccattctga gtaaggtggg tggtttctca
     1921 gtttttaggg atatagtttt aaactatata tctgactatc taataacaat ttgtgaaatc
     1981 aaacaaattg tgagatacta gtacggtatt atttttaagg agaaagaatc atgaaaatca
     2041 aaaaatggct tggcctagca gcccttgcta cagtcgcagg tttggctctt gcagcttgcg
     2101 gaaattcaga aaagaaagca gacaatgcaa caactatcaa aatcgcaact gttaaccgta
     2161 gcggttctga agaaaaacgt tgggacaaaa tccaagaatt ggttaaaaaa gacggaatta
     2221 ccttggaatt tacagagttc acagactact cacaaccaaa caaagcaact gctgatggcg
     2281 aagtagattt gaacgctttc caacactata acttcttgaa caactggaac aaagaaaacg
     2341 gaaaagacct tgtagcgatt gcagatactt acatctctcc aatccgcctt tactcaggtt
     2401 tgaatggaag tgccaacaag tacactaaag tagaagacat cccagcaaac ggagaaatcg
     2461 ctgtaccgaa tgacgctaca aacgaaagcc gtgcgcttta cttgcttcaa tcagctggct
     2521 tgattaaatt ggatgtttct ggaactgctc ttgcaacagt tgccaacatc aaagaaaatc
     2581 caaagaactt gaaaatcact gaattggacg ctagccaaac agctcgttca ttgtcatcag
     2641 ttgacgctgc cgttgtaaac aataccttcg ttacagaagc aaaattggac tacaagaaag
     2701 cacttttcaa agaacaagct gatgaaaact caaaacaatg gtacaacatc attgttgcga
     2761 aaaaagattg ggaaacatca cctaaggctg atgctatcaa gaaagtaatc gcagcttacc
     2821 acacagatga cgtgaaaaaa gttatcgaag aatcatcaga cggtttggat caaccagttt
     2881 ggtaataaga aacagggagg tgggagagag aattccacct cttgcttttg tatagagcac
     2941 ggagtgtaaa gaagactatt cgttcataga aaggtagaga gaatatggtt tttcctagcg
     3001 aacaagaaca gattgaaaaa tttgaaaagg atcatgtagc ccagcattat tttgaggttt
     3061 tgcgtacctt gatttctaag aaatcagtct ttgcccagca ggttggactc aaggaagtcg
     3121 caaattatct gggtgagatt ttcaagcgtg ttggagctga agtggagatt gatgagagct
     3181 atacagcgcc ctttgtcatg gcacatttca agagttcgcg tccagatgcc aagaccttga
     3241 ttttctataa ccactatgac actgtgccag cggatgggga tcaggtctgg acagaggatc
     3301 cttttacgct ttcggtccgc aatggcttca tgtatgggcg tggggttgat gacgacaagg
     3361 gtcatatcac agctcgcttg agtgctttga gaaaatatat gcagcaccat gatgatttac
     3421 ctgtcaatat cagctttatc atggagggag cggaggaatc ggcttcaaca gacctagata
     3481 agtatttgga aaagcatgca gacaaactcc gtggggcgga tttgttggtc tgggaacaag
     3541 ggaccaaaaa tgccttggaa cagctggaaa tttctggtgg caataagggg attgtgacct
     3601 ttgatgccaa ggtaaaaagc gctgatgtgg atatccactc gagttatggt ggtgttgtgg
     3661 aatcagctcc ttggtatctc ctccaagcct tacagtctct tcgtgctgcg gatggccgta
     3721 tcttggttga aggcttgtac gaagaagtac aagagcccaa tgaacgagaa atggccttgc
     3781 tagaaactta tggtcaacga aacccagagg aagttagtcg gatttatgga ttggagttgc
     3841 ctctcttaca ggaggagcgg atgacctttc taaaacgttt ctttttcgat ctagcgctta
     3901 atatcgaagg aatccagtct ggttatcaag gtcagggtgt taagactatt ttacctgcag
     3961 aagccagtgc caagctagag gttcgtctgg ttccgggcct agaaccgcat gatgttctgg
     4021 aaaaaattcg gaaacagcta gacaaaaatg gctttgataa ggtagaatta tactatacct
     4081 tgggagagat gagctatcga agcgatatga gcgcaccagc cattctcaat gtgatcgagt
     4141 tggccaagaa attctatcca cagggcgttt cagtcttgcc gacgacagcg gggacaggac
     4201 ctatgcatac ggtctttgat gccctagagg tgccaatggt tgcattcggt ctaggaaatg
     4261 ccaatagccg agaccacggt ggagatgaaa atgtgcgaat cgctgattat tacacccata
     4321 tcgaattagt agaggagctg attagaagct atgagtagag atattatcaa gttagatcag
     4381 atcgatgtga cttttcacca aaagaagaga accatcacag cggttaagga tgtgactatt
     4441 cacatccaag aaggggatat ctacggaatc gttggatatt ctggagcagg gaaatcaacc
     4501 cttgtacggg tgattaacct cttgcaaaaa ccatctgcag ggaaaattac cattgacgac
     4561 gatgtgattt ttgatggtaa ggtcaccttg acggcagagc agttgcgtcg taaacgtcaa
     4621 gatatcggga tgattttcca gcattttaac ctgatgagcc aaaagacagc agaggagaat
     4681 gtagcctttg cccttaaaca ctctggactt agcaaggaag aaaagaaggc taaagtagct
     4741 aagttgttgg acttggttgg tttggcagat cgtgctgaaa actacccttc acaactatct
     4801 ggagggcaaa aacagcgtgt ggcaattgcg cgtgccttgg ccaatgatcc aaaaatcttg
     4861 atttcagacg agtcaacttc tgcccttgac cctaagacaa ccaagcagat tttggccttg
     4921 ttgcaagatt tgaaccaaaa attaggcttg actgttgtct tgattacgca tgaaatgcag
     4981 attgtcaaag acattgccaa ccgtgttgca gttatgcagg atgggcattt gattgaagag
     5041 ggtagtgtgc ttgaaatctt ctcagaccct aaacaacctt tgactcaaga ctttatctca
     5101 acagctacag gtattgacga agccatggtc aaaatcgaga agcaagaaat cgtggaacac
     5161 ttgtctgaaa acagtctctt ggtgcaactc aagtacgctg gagcttcaac agacgagcca
     5221 cttttgaatg aattgtacaa gcattaccaa gtaatggcta atattctcta tgggaatatc
     5281 gaaattctcg atggtactcc tgttggagaa ttggtggtgg tcttgtcagg tgaaaaagca
     5341 gcgttggcag gtgcccaaga agccattcgt caagcaggtg tacaactaaa agtattgaag
     5401 ggagtacagt aagatggaat cattgattca aacctattta ccaaatgtct ataaaatggg
     5461 ttgggctggt caggcaggct ggggaacggc tatctactta actctttata tgacagttct
     5521 ttccttcatt atcggaggct tcttggggct agtggcaggt ctctttctcg tcttgacagc
     5581 gccaggtggt gtcttggaga ataaagtcgt attctggatt ttagacaaaa ttacctcaat
     5641 ttttcgtgcg gttcccttta tcatcctctt ggcaatcttg tcaccacttt ctcacttgat
     5701 tgttaaaaca agtatcgggc caaatgcagc ccttgtccca ctttcttttg cagtctttgc
     5761 cttctttgcc cgtcaggtgc aggttgtctt ggctgaattg gatggcggtg tcattgaggc
     5821 ggctcaagcg agcggagcga ctttctggga catcgtgggt gtttacctat cagaaggtct
     5881 tccagatttg atccgtgtga cgactgtgac cttgatttcc cttgttgggg aaacagctat
     5941 ggccggtgcg gttggagctg gtggtatcgg taacgtagcc atcgcttatg gatttaaccg
     6001 ctacaatcac gatgtgacca tcttggcaac catcattatc attttgatta tctttgcaat
     6061 ccaattcttg ggagatttct tgactaagaa attgagccat aaataaaaaa gagccgcgtg
     6121 gctcttttta actgatcaga ttttctgtgc aaatttttta ctcaaggctt gtccaatcaa
     6181 ggcacccact agggctccga tgacaatact tgcgataaat agaaggacag ttccagggtt
     6241 tggagcgacc atgatacggt cgatatattc ttgggatttt cctcttgcca gaagagtagc
     6301 catataggct ttgggcgcaa tccacataag caagattggt cctgttgtac taaaggcgaa
     6361 aataatgaaa gaaaggaagt tctttgtttt gtccttgtat tttcctaatt gagctacttc
     6421 atctgctagg aggccacaga taattccagg aaggaaggaa ccagcaccgt gtttagttcc
     6481 caagaaaaag agggcaatga caaggccgat agtggtaatg gctccaaagc gcggaacttt
     6541 tgcgactagg atcatataga cgctaccgcc gacaagggca gtaaaggcag gcgcataaaa
     6601 catgtttcca gtttggtcaa agagattgcc caaaaggaca ccaatcccca tgcagaggaa
     6661 gtaaagaact gcaaaaagca gtgtagttaa gatagatttc ttcatgaatt gtctcctgat
     6721 aattttttca caattctcat tgtaccacgg tttggtggga ttgtaaatgg atactagaag
     6781 tttttgaaaa cgcttgaaat atgatataat ggtttcatag ttatttttag gggaatatca
     6841 tgggtagatt tttagacttt gtctttaatc gtttcttttt agggatgatt gcgacagcct
     6901 tcttttggct attaacttta gtaggaggga ttatccttgg tctagcgccg gctagtgcca
     6961 ccttgatgag cttatatgca gaacatggtt atagctttcg ggaatacagt ttgaaggagg
     7021 cttggtctct ttacaagcaa aattttgtct caagcaacct gattttctat agctttttag
     7081 gtgtgggtct agttttgacc tatggtttgt atctcttggt gcaattgcct catcagacca
     7141 ttgttcattt gattgcgacc cttttgaatg tcctagtagt tgccctgatc tttttggctt
     7201 atacagtatc tttaaaatta caagtttatt ttgccttgtc ctatcgaaat agtctcaaat
     7261 tatccttgat tggcatcttt atgagtctag cagctgttgc caaggttctc cttgggactg
     7321 tgctacttgt agcaattggt tactatatgc ctgccctgct attttttgta ggaattggga
     7381 tgtggcattt ctttatcagt gatatgttgg aacctgtcta tgaaatcatc catgaaaaat
     7441 tggcgacaaa atagaatgaa gcagttttgg ctacatacgc ttctaagaac ctatagttca
     7501 gtgatgatca ttatcattgc gagttttgca atcttactct cttacgctga ctgggattca
     7561 cgtgaaaagg aagcccagag agtagcccag cgtgtaactg ctagaacagt gagtgaaatt
     7621 gaatattacc atagagagtc aacccagata gctcaggctt tagttgaaaa tcaagctcgt
     7681 attgagggaa tctataaata ctttagcctt agcatgccag actattttta ctggcaatta
     7741 gagcggaaag cttcgcctta tatatcagtc tctctgtatg aaaatgttga tgacctctat
     7801 gttcgaaatg attttgtaac tggagtggcc attgcttttc aagattacaa ggaagtctat
     7861 gtttctacta aagacaaacg tagtggagaa aaaatcaggg ctgaggattt caaaccagta
     7921 ggaaatagtt ttgccattcc ggtgtcagat ccagtgtcag atcaagattt aggagtgatt
     7981 tacatctcct tggatcctgc tgttttatac catgccattg ataatactag aggtcatact
     8041 ccgatggtag taacagtgac ctcacctttt gatacggaga tttttcatat tggtgagaca
     8101 gttgataagg agagtgaaaa ttggctagtt ggcttaactt ctcatggata tcaggttcag
     8161 gtggcagttc ctaaaaactt tgttttacaa ggaacagtga ctagctctgc tttgattgtg
     8221 ggtttgagcc ttctctttat tgtcattctt tatctgactt tgaggcagac ttttgctaat
     8281 taccaaaagc aggtagtgga tttagtagaa tccattcaag tcattgctca aggcgaagag
     8341 gggcgtcgga ttgacatttc cgagaaagat caggaattac tcctaatcgc ggagacgacc
     8401 aatgatatgt tggatcgatt ggaaaagaat atccatgata tttaccagtt agagcttagt
     8461 caaaaagatg ccaatatgcg agccttgcag gcgcaaatca atcctcattt tatgtataat
     8521 acgctggagt tcttgcgcat gtatgcagtt atgcagagtc aagatgagtt ggcagatatc
     8581 atttatgaat tcagtagtct cttgcgtaac aatatttccg acgaaagaga gaccctcctc
     8641 aaacaggaat tagaattttg ccgtaaatac agctatctct gcatggttcg ctatcccaag
     8701 tccattgcct atggtttcaa gatagatcca gagttagaga atatgaagat tcccaagttt
     8761 accttgcaac cgctggtaga aaactatttc gcgcatggtg ttgaccacag gcggacagat
     8821 aatgtgatta gcatcaaggc tcttaaacag gatgggtttg tggaaatttt ggtggtcgat
     8881 aatggtagag gaatgtcggc tgaaaagttg gcaaatatcc gagaaaaatt aagtcagaga
     8941 tattttgaac accaagccag ctacagtgat caaaggcagt ctatcgggat tgtcaatgta
     9001 cacgagcgtt ttgtgctcta ttttggagac cgctatgcca ttactataga gtctgcagag
     9061 caagccggtg ttcagtatcg tattacaatt caagatgagt agaaagggag aaaatgtata
     9121 aagtattatt agtagatgat gagtacatgg tgacagaagg tctgaagcgt ttgattccct
     9181 ttgataagtg ggatatggag gtcgtcgcaa cagccagtca tgccgatgaa gctctagaat
     9241 atgttcagga aaatcctgtc gatgtcatca tttccgatgt caatatgcca gacaaaacag
     9301 gacttgatat gattcgggag atgaaagaga tcttaccaga tgctgcctat atcctgctct
     9361 caggttatca ggagtttgat tatgtaaaaa gagcaatgaa ccttagtgtg gtggactatt
     9421 tggtcaagcc tgttgataag gtagagctgg gaaatctgct ggagaagatt gcaggtcagc
     9481 tcggcgagag agggaagaaa agtcagactc ttagtcaaga attagacgag gctggatttg
     9541 ttagttattt aggggataag gagaattggt ggataggtct atccaaggaa aaacaaggtt
     9601 ccttcaccat tccctactat gtcttgggtc aagactggca gattttcatt tctggccacc
     9661 ccctagatgg tttagtcgtt acaccttttg aagctcctta tcaagaacat tttgaacgct
     9721 ggaagctgaa tgctgagaaa accctctttt acggttctgt aaatctgcag cagtctgaga
     9781 gtctctttgc ctattacgaa ccgatttata gggttatcat tcagggaaat ctcaatcaaa
     9841 tcgtagaaga gttaaatctc ttggagaagg tagttcttga aaatacacct cgtgtttcga
     9901 ttactaaaca gctttttatc cagtttgtca tggatgtttt ccatttattt gaacatctca
     9961 aagctgatga tatgacggac attgtcaaaa ccattcatgc tattcaatcc ttcgatgaat
    10021 tggtttctta tatcaaggaa actctgatca gctttttcgg tcaataccgt atgaatgaaa
    10081 atgtggtcag tgtgctggaa gtcattggtc gtgattacca aaaagagctt tccctcaagg
    10141 atatcagtaa ggccctcttt atcaatcctg tctatctagg gcagttgatt aagcgtgaaa
    10201 ccgattcgac ctttgcagag ttactaaata aacaacgtat taaggctgcc cagcagctct
    10261 tgctttcaac tagtgacagc atcgaagata tttgttatgc tgttggttac agtaaccttg
    10321 gatatttcta taaagttttc cgaaaattgt gcggaaaatc gccaaaagcc taccgaaaac
    10381 aggtagaaac tatactataa gatttgtatt cctttacaaa aggtgctata atattatcag
    10441 gaggtcctat catgaaaaag aaaccaattt atctatgggt tttgctaatc ttgtctgccc
    10501 ttatttcagt tccgtctctg tttggaattg tgagtccctt gcctagtaaa gaagcccttc
    10561 gtgctgctca gaaacaagtt gcaggggtca atgctcagca attagaagac cagcttaatt
    10621 atacctatag agtagcagaa gcatctcatt ctatttttaa tgttgctttg attgtgctat
    10681 ctactatttt agtggtcgta gcgattgtct tccttgttcg taaaaatttg caatatgcaa
    10741 actatactta cgttggctat gttttgttag ctattattgg ttcgatttat ggctatgttg
    10801 gtttacaaga cgctgtgcag ttggttcaag atgagagcat gcgtttgaca gtgagtattg
    10861 gttcaaaagc tgttagcatt ttctatatcg tcatcaatgt tctcttccta gcgcttgtct
    10921 tctataagat gtggcgacaa cagaaagcct tggcagaaga agaggaaaca gaagagcttg
    10981 cctaagtatt gacaaaaaag aactatcaag atacaatctt ggtagttgtt ttttgattat
    11041 agataaaatc atggaggtac atatgaagac aatttcttta gtttatatta gtttgagtgg
    11101 caacactgaa agttttgtga cgcgattgaa agactatctc ttgtcccagt acaaagggat
    11161 tgaggttcaa aagattcata tcaaggattt agtcaaggaa ggcaaaaatt tctatgaaat
    11221 ggaccatccc tatgtcgctt ttttgccgac ctatctcgaa ggtgggaatg gcgtggataa
    11281 cggagatgtt gagattttga cgacaccggt gggagatttt attgcctatg gtaacaatgc
    11341 tagtaagtgt tttggtgtgg ttgggtcagg aaatcgtaac tttaataacc aatactgcct
    11401 aacagccaag caatacagtc aacgctttgg cttccctgta ttggctgact ttgaaatgcg
    11461 aggcatgctg gaagatatca aacatgtcgc agctattatc gcagatttgt atgagttgga
    11521 aaaggagaat taatactcaa tgaaaatcaa agagcaaact aggaagctag tcgcaggttg
    11581 ctcaaagcac agctttgagg ttgcagatag agctgacgtg gtttgaagag attctcgaat
    11641 agtataaagt tcttataaga ggtggttgaa gttgttcaac tgttttttga gtataaacag
    11701 tttttaagaa cgtaaaaaag cataagttca ggtcttcaaa accttgttct tatgcttttt
    11761 atcatagaaa tatttgctga attttctctt gaaatgaaac cttatcttca tctcgcgctt
    11821 gtcccttacc ctgcttttcc gattgcgagt gcgtagataa agaagatggc gaagccaaag
    11881 aggaaaatca atcccgcaat ggcaaggtgt ttgagccaag aaggaagatt tttgttttca
    11941 cgcgttacca aggcgtaatt caaaagagca aagaaaggtg ttgtcaggaa agagccaatc
    12001 atggcaaagc ggagcatggt tgaaacctga ccagcgaaga acttgataat gacgataccg
    12061 atgatagcag tgatggtcat ccagatgttc aaagatttac gattgtcctc tttttgactg
    12121 attagcagtc ggagagattc ctgattaacg cgagaatagc catcgataac agttataact
    12181 gttccaaaga tacagaggaa ggcaataaag gtaatcaagt aacgggacca ttcgccaaga
    12241 acagaggcat acatgcccac gaattgagag atgtatttgg ctgaagcagc ttcaaccgcc
    12301 tgccctgtag gatactgaat cagtgctccc agtgccacaa agaagacggc taggatagct
    12361 gttccaatat aaccagtgtt aaagtcaaac agagcgtctt ctgtgttaaa gttgacggtc
    12421 tttctctttt cagctgacca aagtgaattg atggctgaaa tttcaatagg agccggcatc
    12481 catcctagga gggagacgat gaagggcaga gctgccattt gccaaggtgt cttctcgaca
    12541 aaatcagaac tgtattctgg atgcttgacc gccgcaatga taactgcaag aacagtcgca
    12601 atggttaagg cagacataat ccatttgacc atgccgtcta aaagtttgta gcctccaaag
    12661 agtagcatag cccaaatgat tgcaacgaga atgagggacc actgagtaat gctaagtcca
    12721 atcattggga aggcactggc gatgatagct gagcacagaa tggcaacacc agccgtgttg
    12781 accatagccg aaaagacatt gaggataaag aaaatccaga gatagagttt tcctttttcg
    12841 gcataacctt caaccaaagt ctttccagta tcagctgtgt attcagcacc aaaacggaaa
    12901 aatggatatt taaagacatt ggctaagatg accaagagaa gtagagacca accgtaagaa
    12961 ccgccagctt gagttgagga tacaatgtgg gaacctccaa cagcggcagt tgccattagg
    13021 attccaggtc ccattgcttt tagcttgctt gcccaggttg attgatttaa ggaaatagct
    13081 tgcgacatga taaatactcc tttttgaatt ttcagaataa tctgtatatg taatctatat
    13141 tctacaaaaa attttgaaaa aatgcaagag tattttgaaa aaagatagaa aatttacaaa
    13201 gaaaatctga aataactgtt atgatataga ggattgaaac tagaatagta cacctctgct
    13261 tctaaaacat tgttagaaat cgatttgact gtcctgatcg atttatcctg ttcttatttc
    13321 atttcactat agtaaggtgc agcaggataa agaaaaaccg agaagtttct ttctcggatt
    13381 tgcttattat gaggttccta ttttctatgc tccaagagtt gattgatgtg atctactttt
    13441 ttagcctctc ttttatagag aatagcccag atgatgagat agacaatcgc aaactcgata
    13501 atgagctgga ggtagaaaat ccagtggaaa gggaaccaac cagcaagagt tgctagtggg
    13561 acaaagccag ccagcataag gaagaaatga gtcagagtgg cacgaagcat gctccagtca
    13621 cggctaaata agcggttgcc aaagttgaag agcataccga tggttgccca gataagtgtg
    13681 cagtagagca agaccagggc accgtgaacc tgatgctgat ccatcacttg gccgatgaga
    13741 gagtagggat ttagtggtgc gtaggtattt ggtgcataaa tgagtgaaaa gaggatagag
    13801 aggatgaggc cgataagaac accggtagct gcatcgtgaa atacttgttt tttcatagtt
    13861 ctaatttctc cttgatggtt tttagataac ggcgtgaaga gtaggtgaag ctttcgtttt
    13921 tcaagaaaat ttctaccaga ccgtttggcg tgagcttgag gtgagagatg gaatcgatat
    13981 tgatgatttc tgattgggaa atttggataa aattgcttgg caagagttta ggaacctgat
    14041 agagtcgcaa atcaatgctg taggtctgac tcgcggtttc tgctagaacc ttccgattct
    14101 cgatatagaa gcgctgaatc ttgccaatct caactagata gacctgatca tcgcttttcc
    14161 ctttgatttt ttctctttgg tccagatttt ctgcgaactc gatgactttc tggactttat
    14221 ctgtcggctg aggtgcttgg acaatcagct tttcctcctc gtaagtctca ctaatctgta
    14281 gttctacttt cataaatttc tctccttgtt tttcatacaa aattaatctc acttcttgta
    14341 cacctttatt aatactcttc aaaaatctct tcaaaccacg tcagcgtcgt cttgccgtag
    14401 gatagttgtt gactttgtca gttttatcta caacctcaaa acagtatttt gaactgtctg
    14461 cgcctagctt tctagtttgc tctttgattt ttattgagta taccactatt ttactccctc
    14521 tggcaaggga ctttgtctat gtggagggat tgggctccta tgtggtggag cttttctgtt
    14581 ctttctgaaa tatggtataa tagcactaat taatttctag gaaaatagat acagaaaggg
    14641 gctgaaagat gtctcatatt attgaattgc cagagatgct ggcaaaccaa atcgcagctg
    14701 gagaggtcat tgaacgtcct gccagtgtgg tcaaagagtt ggtagaaaat gccattgacg
    14761 cgggctctag tcagattatc attgagattg aggaagctgg tctcaagaag gttcaaatca
    14821 cggataacgg tcatggaatt gcccacgatg aggtggagtt ggccctgcgt cgccatgcga
    14881 ccagtaagat aaaaaatcaa gcagatctct ttcggattcg gacgcttggt tttcgtggtg
    14941 aagccttgcc ttctattgcg tctgttagtg tcttgactct gttaacggcg gtggatggtg
    15001 ctagtcatgg aaccaagtta gtcgcgcgtg ggggtgaagt tgaggaagtc atcccagcga
    15061 ctagtcctgt gggaaccaag gtttgtgtgg aggatctctt tttcaacacg cctgcccgtc
    15121 tcaagtatat gaagagccag caagcggagt tgtctcatat cattgatatt gtcaaccgtc
    15181 tgggcttggc ccatcctgag atttctttta gcttgattag tgatggcaag gaaatgacgc
    15241 ggacagcagg gactggtcaa ttgcgccaag caatcgcagg gatttacggt ttggtcagtg
    15301 ccaagaagat gattgaaatt gagaactctg acctagattt cgaaatttca ggttttgtgt
    15361 ctttacctga gttgactcgg gctaaccgca attatatcag cctcttcatc aatggccgtt
    15421 atatcaagaa cttcctgctc aatcgtgcta ttttggatgg tttcggaagc aagcttatgg
    15481 ttggacgttt tccactggct gtcattcaca tccatatcga cccttatcta gcggatgtca
    15541 atgtgcatcc aactaagcaa gaggtgcgga tttccaagga aaaagaactg atgaccctgg
    15601 tttcagaagc tattgcaaat agtctcaagg aacaaacctt gattccagat gccttggaaa
    15661 atcttgccaa atcgaccgtg cgcaatcgtg agaaggtgga gcaaactatt ctcccactca
    15721 aagaaaatac gctctactat gagaaaactg agccgtcaag acctagtcaa actgaagtag
    15781 ctgattatca ggtagaattg actgatgaag ggcaggattt gaccctgttt gccaaggaaa
    15841 ccttggaccg attgaccaag ccagcaaaac tgcattttgc agagagaaag cctgctaact
    15901 acgaccagct agaccatcca gagttagatc ttgctagcat cgataaggct tatgacaaac
    15961 tggagcgaga agaagcatcc agcttcccag agttggagtt tttcggacaa atgcacggga
    16021 cttatctctt tgcccaaggg cgagatggac tttacatcat agatcagcac gctgctcagg
    16081 aacgggtcaa gtacgaggag taccgtgaaa gcattggcaa tgttgaccag agtcagcagc
    16141 aactcctagt gccctatatc tttgaatttc ctgcggatga tgccctgcgt ctcaaggaaa
    16201 gaatgcctct cttagaggaa gtgggcgtct ttctagcaga gtacggagaa aatcaattta
    16261 ttctacgtga acatcctatt tggatggcag aagaagagat tgaatcaggc atctatgaga
    16321 tgtgcgacat gctccttttg accaaggaag tttctatcaa gaaataccga gcagagctgg
    16381 ctatcatgat gtcttgcaag cgatctatca aggccaatca tcgtattgat gatcattcag
    16441 ctagacaact cctctatcag ctttctcaat gtgacaatcc ctataactgt cctcacggac
    16501 gtcctgtttt ggtgcatttt accaagtcgg atatggaaaa gatgttccga cgtattcagg
    16561 aaaatcacac cagtctccgt gagttgggga aatattaaaa gtataaaaaa gtctgggaaa
    16621 aattttcaaa atcagaaaaa cgcataaaat caggtgttca aaaaccttga ttttatgcgt
    16681 tttatcatgg aaatagttac ttcatgtttt cctaattctt ttcgaaactc tttttaaacc
    16741 acgtcagttt tatcagtaat ctcaaaacag tgttttgagc taattttgcc agttttgtct
    16801 gtaacatcga agttgtgttt taccactctg cgactggttt cctagtttgc tctatgattt
    16861 tcacagagta ttaaattgcg attttgccaa gtttctttat tcgtctaaaa gtagagtctg
    16921 ttctatgcgt ctaatgtacg aattaggttg accatttcaa tagctccttg tgcacactca
    16981 gaacccttat ttcctgcttt ggtaccagct cgttctatgg cttgttcaat tgtatctgtc
    17041 gttagcacac caaacataac aggaatttcg ctatttaaac tgatttgggc gattccctta
    17101 gatacctcgc tacatacata atcataatga cttgtattcc ctctaatgac agctcccaag
    17161 cagataattg catcatattt tttacttttt gccatttttg atgcaatcag tggtatttca
    17221 aaagctcctg gaacccaggc tacctctata tctttctcgt ttacattctc tcttttgaga
    17281 ttatctagtg ctccagataa taattttgaa gttataaatt cattaaatct cgctacaaca
    17341 atacctattt taatattgtt tgctactaaa ttaccttcat aagtgttcat ttatttttcc
    17401 tccatattta aaatgtgacc cattcgattt ttctttgttt ctaaataaaa actatcgtaa
    17461 ggattggctt ctatttcgat tgatattcta ctggaaatgg taattccata tttttctaac
    17521 tgttcaacct tgtcaggatt atttgtcagt aaatgaagtg actgaagtcc cagatcttta
    17581 agcatttgtg ctccaatatg atattctctt aaatcacctt caaagcctaa tgcaagattg
    17641 gcatcaagcg tatccatgcc ttgatcttgt aaatgatagg cttttaattt attgataagt
    17701 ccaattcctc gtccctcctg tcgcaagtaa agtaagacac ccgaaccatt ctcaacaatc
    17761 attttcatag ctttatcgaa ttgctgtcca caatcgcaac gtaaagagcc taaaacatct
    17821 cctgttaaac attcggagtg gacccgacat aatacattgg cttcatcctc tatgtttccc
    17881 ataataagag caagatgatg ttccccattt agtttatcta tatagctaat tgctttgaaa
    17941 ttaccgtatc tagtaggcat attgacagtt gaaactcgtt ctaccagctg atcatatact
    18001 tttctatatt cttgtaattc tttgatggta attagtggaa tgttgtgttt cttcgaaaac
    18061 tgaattaaat catctgttct catcattttg ccatcatgat tcattatttc acaacatagg
    18121 ccacactctt ttagtccagc taattttaat aaatcaacag ttgcttctgt gtgtccattt
    18181 ctttctagaa caccaccttt ttttgcaatt aaaggaaaca tgtgtcctgg cctgcgaaaa
    18241 tcagagggtg ttatatcttc agctacacac atacgtgcgg tcagtcctct ttcctcggca
    18301 gaaatacctg tggtcgtttc tttataatca attgaaactg taaaagcagt cttatgatta
    18361 tctgtattgt tttcaaccat aggtgaaagc attaattgat tagctaaact ttcgctcata
    18421 ggcatacaaa ttaatccttt ggcataagta gccataaaat taacattttc tgttgtagct
    18481 gcttgtgcag aacaaattaa gtctccttca ttttctctat ccttgtcgtc tataacaaga
    18541 acaagtcgtc ccttctgcaa tgcttctaat gcttcttgta tttttcgata ttccattgac
    18601 tgattatcct ttctgctaaa atccattttg atataatagt tccttagata tttctgattt
    18661 tggagagtta tccatcagtt tttgcacata tttacctaag atatcatttt caagatttac
    18721 tgtactcccg acttgtttac tcttaagaat ggtttgttcc aaggtatgag ggataacaga
    18781 tactgaaaag tttactttgg agactttagc gacagtcaga ctaatgccgt caattgtaat
    18841 agatcctttt tcaactatta aatctaaaat ttctttttgt gtgttgattt gataccatac
    18901 agcattatca tcttttttta ttgacgagat ttttcctgta ccatcaatgt gtcctgtaac
    18961 gacgtgaccc ccaagtcgac cgttgacaga taaggctctt tctagattca cctcacttcc
    19021 atgttttaat agagtaagag ctgttcgact ccatgtttca ttcattacat caactgtaaa
    19081 ggattgatga ttgaaatgag taactgtaag acagatacca tttactgcta tactatcacc
    19141 taaatggata tccgttaata tttttgaggc tttaattgat agtttacaat tacgagagtc
    19201 tttctgtatt ctttcaactt ttccgatttc ttcaattatt cctgtgaaca tggataaatc
    19261 acttcacttt ctatgagata gtcatttcct atttgagaaa aagcataagg tttcaatcta
    19321 atagcgtcat ttggcaaaga aatgccttca cctccgacag gaaacttggc actgcctcca
    19381 aaaatttttg gtgcaatata tattttcagc tcatcaacaa tttgttgttc caaagcactc
    19441 caattcatta gactgccccc ttctagaact aggctatcaa tctgcatgtt tcctagatgt
    19501 tgcattaaac tcgataagtc tatatgattg ccttttttct ttatggaaag tatttcacag
    19561 ccatgatttt gatatagctt cattttattt ttgtcttcag aggaagtggc aatgtaagtt
    19621 ttaatatcat ttgctgtttt tacgatttta gaggtaagag gagttcgtaa atgtgtatcg
    19681 catatgatac ggataggatt tttcccttcc tccaatctac atgtcagcaa aggatcgtct
    19741 tgaataacag tattgactcc caccataatt gcactaacat ggtgtcgtaa ctgatgcaca
    19801 tgctttcttg cttcttcttc agtaatccat ttggattgat ttgttttagt ggctattttt
    19861 ccatccattg acattgcata tttcataaaa acatagggta catgctgggt aatatacttt
    19921 ctaaaacttt ttattaagtt aagacactca ttttctaaaa ttccaacagt aacttgaaga
    19981 ttattttcct caagtatctt tactcctttt ccagatacaa taggattaca gtctaggctt
    20041 ccaatgacta ctcttgtaat accactatcg attatagcat ctatacaggg aggtgttttc
    20101 ccgaagtgac aacagggttc aagtgttaca taaagcgtcg ctccgacagg ggattttcta
    20161 cagtttttaa gagcatttct ctcagcatgt gggccaccaa aaaactcatg ataaccttgt
    20221 ccgataatgt gattatcttt tacaataatt gcgccaacca taggattggg attgacgtaa
    20281 ccagcccctt tttgtgccag ttttattgct aatttcatat attttgaatc gctcatctca
    20341 ctacctccaa aaaaatatac cttgaatagg ggactactca aggcatacaa aagaaaactt
    20401 atgcgattaa caaaaatgct ctgaaatgac aagtaatcat ttcagagcac gcaaaaagca
    20461 caaatatact tttatcttct ttcatccaga ctatactgtc ggctttggaa tttcaccaaa
    20521 tcatgccttt cggctcgtgg gctataccac cggtagggaa ttgcaccctg ccctgaagat
    20581 agttattcaa ttacagatga ttatagtact taattttgaa tatgtcaaca gataaatacc
    20641 gattgttttt gatatactgt atttgtgata atcgattctc gctcctcgga taaagaaaat
    20701 atgatatact agataaacga aataagagag aaggaacact atgtacgcat atttaaaagg
    20761 aatcattacc aaaattactg ccaaatacat tgttcttgaa accaatggta ttggttatat
    20821 cctgcatgtg gccaatcctt atgcctattc aggtcaggtt aatcaggagg ctcagattta
    20881 tgtgcatcag gttgtgcgtg aggacgccca tttgctttat ggatttcgct cagaggatga
    20941 gaaaaagctc tttcttagtc taatttcggt ctctgggatt ggtcctgtat cagctcttgc
    21001 tattatcgct gctgatgaca atgctggctt ggttcaagcc attgaaacca agaacatcac
    21061 ctacttgacc aagttcccta aaattggcaa gaaaacagcc cagcagatgg tgctggactt
    21121 ggaaggcaag gtagtagttg caggagatga ccttcctgcc aaggtcgcag tgcaagcaag
    21181 tgctgaaaac caagaattgg aagaagctat ggaagccatg ttggctctgg gctacaaggc
    21241 aacagagctc aagaaaatca agaaattctt tgaaggaacg acagatacag ctgagaacta
    21301 tatcaagtcg gcccttaaaa tgttggtcaa ataggagcag agaatgacaa aacgttgttc
    21361 gtgggtcaag atgaccaacc cgctctacat cgcctatcat gatgaggagt ggggccagcc
    21421 cctccatgat gaccaagcat tgtttgagtt gttgtgtatg gaaacctatc aggcaggcct
    21481 gtcttgggaa acggtactca acaaacgcca agctttccga gaagcatttc atagctatca
    21541 aattcactca gtcgcagaga tgactgacac tgaattggaa gccatgctgg agaatccagc
    21601 tatcattcga aatagagcca agatttttgc tacacgcgct aacgcccaag cttttctaca
    21661 gttacaggca gagtacggct cttttgatgc ctatctttgg tcttttgttg aggggaaaat
    21721 tgtcgttaac gatgttcctg attatcgcca agcgccagct aaaacaccct tatctgagaa
    21781 attagccaaa gatctcaaaa aacgaggctt caagttcaca ggcccagtcg ccgtattgtc
    21841 ttttctacag gctgcagggc tagttgatga ccacgagaat gattgtgagt ggaaaggtct
    21901 taaatgatgt ctaacaaaaa taagggaatt ctgatttttg cgattctcta tacagtcctc
    21961 tttgtgtttg atggcgttaa attgctggct tctttaatgc catctgtcat tgcaaattat
    22021 cttgtttatg tagttttagc tttatatggc tccttcttgt tcaaggatag attgatccaa
    22081 caatggaagg agattagaaa gactaaaaga aaattcttct ttggcgtctt aacaggatgg
    22141 ctctttctca ttctgatgac tgttgtcttt gaatttgtat cagagatgtt gaagcagttt
    22201 gtgagactag atggacaagg tctaaatcag tctaatattc aaagtacctt tcaagaacaa
    22261 ccactactga tagctgtttt tgcttgtgtc attggacctc tggtagaaga attatttttc
    22321 cgtcaggtct tattgcatta cttgcaggaa cggttgccag gtttactaag cattattctg
    22381 gtaggacttg tttttgctct gactcatatg cacagtttgg ccctatcaga gtggattggt
    22441 gcagttggtt acttaggtgg aggccttgcc ttttctatta tttatgtgaa agaaaaagag
    22501 aatatctact atcccctact tgttcacatg ttaagcaaca gcctctcctt aatcatttta
    22561 gctatcagta tagtaaaatg aaataagaac aggacaaatc aatcaggaca gtcaaatcga
    22621 tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaataca ctgtaacatg
    22681 tgatgaaaat gccagtaatg ataccgagaa aaaagctgag aaacttttcc cagctttatt
    22741 tgttatagtc aaagcgaatg acttgttcct gtgcatctac atgagcatgg accccaaagg
    22801 gtacaattgc tcttggagtt gcgtggccga cattcagatt atagacaatc gggatattgt
    22861 tgtcaatgat atccaatagt gcctctttat agtcgtcatg gaaagtttca tccataggtt
    22921 ttccgaccaa gagtccattg atgaccgcga atatgccagt gtcctttaaa gttagcaaca
    22981 tctttttgaa gtcttctggc ttaggctttt cttcgcttgt ttcgagcaag aggattttcc
    23041 cttcccagtc tgacaagtca gggaaaagtt tgtatttttg gcagagctcc gtgctatctg
    23101 cgtatcgaga gttgtcaaag atatcgtaga gggattcgag gcaaccaccg aggattttcc
    23161 cctcgaactg agcacttcct tgcaacaagt caaaacctgt atttgtatga ctgacacgag
    23221 gtgttcccag ggccgtggga ctaaaatcag ttcgttcctc ataccaaacg tcactagggc
    23281 ggatttctga aattcttccc gtctcaatca attctttaaa gtagtgaagg ctataggcta
    23341 gcatttcttt gtctaattca caaatgtctg ctaaaaagga ttgaccataa aaagtcttga
    23401 ttcctaattt atgcaacatg aggtggttca tggttgtatc cgagaagcca agaaaaattt
    23461 tttgcttgat aaccttttgg agttggtcat tttcaaaaag ataaggtagc aagcgatagg
    23521 tatcgtctcc accgatggca cataggatca tgtcgatgct atcatcagaa aaggcatgaa
    23581 tcaaatcctc tgcacgagct tcaggatggt ccttgataaa gtctaatcct tttaacgaat
    23641 ggggcaaaaa gatgggattg agtcccagat ccttgagacg ttggataccc aagtccactt
    23701 cgtgtttgac aaaatcctct ccgataatgc cactagataa actaacaata ccaatagtag
    23761 aaaccatatc tcatcctcct agaaatagat tgagcctatt ttatcacaaa atataagaga
    23821 aagctatgtg ggatttcaga agaatacttt taatactctt cgaaaatctc ttcaaaccac
    23881 gtcagtttta tctgcaacct caaagctgtg ctttgagcaa cctgcagcta gcttcctagt
    23941 ttgctctttg attttcattg agtataactc aaaaaagtaa gtgaaaaagc aaccgcacct
    24001 gcagttgctt ttatcgtttt cttattcttg atagcgtgtt ggtcctgcac ttgcactacg
    24061 gatattcaag cgtttcttga gatagaagcg aagggctagg agggctgctc caataatagc
    24121 tagtggcaat ggatccagta ctgggttaag gctagctggt aggaagcttg ttgcaaagaa
    24181 gacaagcaac caaaggaaca tagaagctag gataactagt acagatttcc agaaaggtgg
    24241 acgttgactg cgatccatat ctggtccata gtattggtaa acaaagtagt acatcaagta
    24301 gaaggcaaat ccaccaacca gtccaactaa tagaagagta atcaatccat agccgaaagc
    24361 ttggtctgcc gcaaagaagg ttgtgagggc gctgacaagg gcaaagaggc tagtgatgaa
    24421 aagagctgag tccataatca tcagttttgg gtcatcattt tcttttggat gctctttttc
    24481 gtactgctct ttgacagtga agctatgagc ccaatgagtt ggtgcgccgt atagggaacg
    24541 ggcagttgta cctttagatt gctcctcaag gatttgggga atgacttcct caaaaatagt
    24601 ctggatttca gcgtctgttt tcccatcttt gatgaattgt tgggtagcaa tgtggacaaa
    24661 ctcttggttt ttcttagtta atttttgtag atcaatttga gacataggaa ctcctcttag
    24721 aaccattttt tatggatgag atagagagtg agcgagacac tcatagcaaa ggcgataaag
    24781 acgattaacc agaaggcatt tggctctccg tttaggggga tttcattatc cttaaagttc
    24841 atcccgtagg cagaaaagac catggttggg atggacatga cgatggtcac aagggccaag
    24901 gttttcatga tgttgttctg gttgttagaa atgatagagg caaaggtctc tgtcatagaa
    24961 tgcaagacgt ttccataaat atctgccatc tcgatggcct gttgggtttc aatcagggtg
    25021 tcttcaagca ggtcttcgtc ctcaaggtat ttcttgatat tgctggttga actggtcaat
    25081 ttcttaatca cgcgctcatt tgttttgagg gaggccttga aatagacgat agttttttcc
    25141 aattccatga gctcaatcaa ttcttcatta cgagttgatt gatgcagttg actttcgatt
    25201 tgttcactct tgcggtcgat tgaacgaagg gctgttaggt aaagctctgc attgcgataa
    25261 agaatttgaa agataaaacg tgaacgcatg aaggtataga aattacgcaa tcgacggttg
    25321 ataaagacat caaggacagg tagtggttcc aaacacgtag tgataatggt ttcctcagtg
    25381 atgataatac caagcgggat ggttacgtag taggtgcggt tatttctttc ctccgtgacc
    25441 ggcacgtcta cgataatcag ggtatactcg tcttcaatgg taatacgaga catttcttcc
    25501 gcatcgagcg gtgctcgaag gtcggcaata tcaatatcga aggtgttggc gatttcgagt
    25561 gattcatttt gagtcggatt gacgagattg atccaagtac ccggttcaag cgtatcgatc
    25621 tctttaaatt cagttgttgt agagagaaaa acttgtttca tatcccttat cctttctcat
    25681 ttttcagatt ttttcacact gtactattat actacaaaat cggccttttg ggtaatagaa
    25741 tctcactttt tttggtataa tggtaagcaa taatggacta gaaagaacaa agatgcaaga
    25801 taaaattgtc attcatgggg cgcgtgccca taatttaaaa aatattgatg tggagattcc
    25861 gcgagacaag ttggttgtcg tgactggctt gtcaggttca gggaagtcca gtctggcttt
    25921 tgatactctc tatgcggagg gacaacgtcg ctatgtagag agtttgtccg cctacgctcg
    25981 tcagttcttg ggaaatatgg aaaaaccaga tgtagatgcc attgatggtc tcagcccagc
    26041 tatttccatc gaccagaaaa cgactagtaa aaatcctcgc tcgacggtgg gaacgacgac
    26101 tgaaatcaat gactatctgc gtctcctcta cgcacgtgtg gggacgcctt actgtatcaa
    26161 cggacatgga gctatcaatg cttcttctgt ggagcaaatc gttgataagg ttttggagtt
    26221 acctgaacgc cagcgcttgc agatcttggc tcctgtcatc cgcaagaaaa aaggtcaaca
    26281 taagagtgtt atcgagaagg ttcagaaaga cgggtatgtt cgtgttcgtg tggatgggga
    26341 agtctatgat gtgaccgaag tgccagagtt gtctaagagc aagcaacaca atatcgatgt
    26401 cgtggttgac cgtattgtta tcaaggaggg cattcgtagt cgtctctttg attccattga
    26461 ggctgccctt cgtattgcag aaggttatgt cattatcgac accatggacg attcggagtt
    26521 gctcttctct gagcattatg cctgtccagt ttgtggtttt actgtcccag agttagagcc
    26581 tcgtctcttc tctttcaatg ctccttttgg ctcttgtagt gagtgtgacg gcttgggcat
    26641 caagctggag gtggatactg atttggtagt gccagatgcc agcaaaacct tacatgaggg
    26701 agcgctggca ccttggaatc ctatctcatc caactactat ccaaacatgt tagagcaggc
    26761 catgaaagtc tttggagtgg ctatggataa gccttttgag gacctgtcag aagaagataa
    26821 gaacttgatt ctctacggct cagatggtaa ggaattccat ttccattatg aaaatgaatt
    26881 tggtggtgtg cgcgatatcg acattccgtt tgagggagtt atcaataata tcaaacgtcg
    26941 ttaccatgaa accaatagcg attacactcg cactcagatg cgtctctaca tgaatgagct
    27001 gacctgcgga acctgtcaag gctatcgtct caatgaccag gccttgtctg tccgtgtggg
    27061 cggccagcaa gggccacata ttggagaaat ctcagacctg tctatcgctg accacttgga
    27121 cttggtgagc cagttaactt tgtctgaaaa tgaagccatc attgctcgtc ccattctcaa
    27181 ggaaatcaag gatcgtttga ccttccttaa taatgtgggt cttaactatc taaccctgtc
    27241 acgttcagca ggaacccttt caggtgggga aagtcagcgc attcgtttgg caacccagat
    27301 tggttccaac ctatcaggtg tcctctatat cctagacgag ccgtcaatcg gtcttcacca
    27361 gagggacaat gaccgcctga ttgccagtct gaaaaagatg cgtgacttgg gcaatactct
    27421 tatcgtggtg gaacacgacg aagataccat gcgtgaagct gattatctga ttgacgttgg
    27481 tcctggtgcc ggtgtttttg gtggtgagat tgttgcagca ggtacaccta agcaagtggc
    27541 tcgcaacagc aagtctatca caggtcagta cttgtcaggc aaacgtgtca tcccagtacc
    27601 agaagagcgc cgtgtcggaa atggtcgttt tattgaagtg acaggagcgc gtgagaacaa
    27661 cttgcaaaat gtcacggctc gctttccact aggaaaattt atcgcagtga caggtgtgtc
    27721 gggttcaggg aaatcgactc taatcaacag cattctcaaa aaagccatta cccagaagct
    27781 caaccgtaat tcagacaaac ctggtaagtt taagactatt acagggattg agcatgtcga
    27841 ccgtttgatt gatattgacc agagccctat cggacggacg ccgaggtcta acccagctac
    27901 ctatacagga gtttttgacg atatacgtga cctttttgct cagacaaatg aagccaagat
    27961 tcgaggctac aagaaggggc gcttcagttt caacgtcaag ggaggtcgct gtgaagcttg
    28021 ctcaggtgac gggattatca agattgagat gcacttcttg ccagatgttt atgtggcttg
    28081 tgaagtttgc cacggaaccc gctataacag tgaaacccta gaagttcact acaaggaaaa
    28141 gaatatttcg caggtcttgg atatgacggt caacgatgcg gtagaatttt tccaacacat
    28201 tccgaaaatt caacgcaaac tccagaccat caaggatgta ggtctaggct atgtgacctt
    28261 gggacagcca gctaccaccc tttctggggg agaagcccaa cgtatgaagt tagctagcga
    28321 actccacaaa cgctcgacag gaaaatcttt ctacattctg gatgagccga cgacagggct
    28381 tcatacagag gacattgctc gcctgctcaa ggttttagct cgctttgtag acgacggcaa
    28441 tacagtcctc gtcatcgagc acaatctgga tgttatcaag acggcagacc atatcattga
    28501 cttgggacct gagggcggtg tcggtggtgg aaccatcatc gtaacaggaa ctccagaaga
    28561 agtagctgcc aacgaagcca gctatacagg acactatttg aaaggaaagt tacatcatga
    28621 ataaacgcgt acaagcattt ctagctaaaa tgcaagaaaa agaactagat ggtatcatca
    28681 tcaacaatct taaaaacgtc tattatttga ctggtttttg gggctcaaac ggaacagtct
    28741 ttatcagccg tgaccgtcag gtcttagtga cagactctcg ctatatcatc gcagctaagc
    28801 aagaaaccag tggttttgag attgtggctg atcgtgatga attggctgtc attgcaggaa
    28861 ttgttaagga catgaacttg actcgtatcg gttttgaaga tgagatttca gtgtcttatt
    28921 accaccgtat gcaggcagct tttgcaggtt tgaacttgct tacacaaact cagtttgtgg
    28981 aaggtcttcg tatgattaag gatgaggcag agattgcagc gattcgcaag gcttgttcta
    29041 tctcagacca agctttccgc gatgcgcttg actttatcaa accaggaaaa actgaaattg
    29101 agattgccaa cttccttgac ttccgcatgc gtgagttggg agcatctggc ttatcttttg
    29161 atacgatcct agctagcggt atcaattctt ctaaacccca tgcccatcca atgcacaaac
    29221 cagtggagtt gggagaagcc attaccatgg acttcggctg tctctatgac cactatgtca
    29281 gtgatatgac ccggactatc tatctagggc atgttagcga tgagcaggca gagatttaca
    29341 atacggttct aaaagcaaac caagccttga ttgaccaagc taaggcaggc ttaggtttcc
    29401 gtgactttga caaaatccct cgtgatatta tcattgaggc aggttatggc gactacttta
    29461 ctcacggcat tggccacggt attggtctgg atatccatga ggaaccctac tttagccaga
    29521 cttctacaga aactattaag acaggtatgg ccttgaccga tgaaccaggt atctatatcg
    29581 aaggcaaata tggcgttcgt atcgaggatg atatcctgat tacagagaca ggttgtgaat
    29641 tattgaccct agctccaaaa gagttgatag tcatttagtt gtttgtcaag aaaaaagtac
    29701 gaaaatgacg aaaaaagtca aaaaaaatta aaaataggtc gcaagtcgga tgttttttat
    29761 ggtataatag actaaactga tagtaacatg tagcgaaagg ggtaggtaca tgattaaaat
    29821 ttatacagtc tcaagttgta ctagctgtaa aaaagcaaaa acctggctca atgcccacca
    29881 gttaagttat aaagaacaaa accttggtaa agaaggaatt acgagagaag aattactgga
    29941 tattctaacc aaaacagata acggaatagc cagcatcgtt tcgtctaaaa atcgctatgc
    30001 caaagccctt ggagtggata ttgaagattt gagtgtcaat gaagttctca atctgattat
    30061 ggaaacaccg agaattttaa agagcccaat ccttgtagat gaaaaacgcc tgcaagttgg
    30121 ctacaaggaa gacgatattc gtgccttcct accacgctct gtccgtaatg tagaaaatgc
    30181 agaagcacgt ttgcgtgcag ctctataaac atcaaggctg ggagcacttc ccagtcttat
    30241 tctattttaa tttcaaaaag aaagaagaaa gaaatgaaaa aaatagttct tgttagtcta
    30301 gctttccttt ttgtcctggt tggttgcgga cagaaaaaag aaactggacc agctacaaaa
    30361 acagaaaaag atacgcttca gtcggcattg ccagttattg aaaatgctga gaagaataca
    30421 gttgtaacta agactttggt cttgcccaag tcagatgatg gtagccagca gacacaaaca
    30481 attacttaca aagacaagac ttttttgagt ctaactatcc aacaaaaacg tccagtctct
    30541 gatgagttga agacttatat tgaccaacat ggagtggagg aaactcaaaa agctcttctt
    30601 gaagcggagg agaaggataa gtctatcatt gaagctcgta aattggcagg tttcaaactt
    30661 gaaacaaaac tattgagcgc aacggaactt caaacaacga ctagttttga ttttcaagtt
    30721 ctggatgtca agaaggcttc ccagttggaa catctgaaga atattggttt ggaaaatctt
    30781 ttgaaaaatg aaccaagcaa ctatatttca gatagattgg caaatggcgc gacagaacaa
    30841 tagaaaatcc aaataaatag actgcctgaa ttgtagaagg taaggaatta tgctataatg
    30901 gtactattct aaggaaagag ggtgttagaa tgggatttac tgaagaaaca gtacgtttta
    30961 aattggacga ttccaataaa aaagaaatta gcgaaacttt gacagatgtt tatgcttcgt
    31021 tgaacgataa gggttacaac ccaattaacc aaatcgtagg ttacgtattg agtggagacc
    31081 ctgcctacgt tcctcgttat aataatgcac gaaatcaaat ccgtaagtat gagcgtgatg
    31141 aaatcgttga ggaattggtt cgctactacc tcaaaggaca aggagtcgat ctataaccta
    31201 tgagaattat gggattggac gtcggttcaa aaacggtagg ggtggcgatt agcgatccgc
    31261 ttggttttac agctcaaggg cttgaaatca tccagataaa tgaagaacaa ggccaatttg
    31321 gttttgaccg cgttaaggaa ttggttgata cttacaaggt ggaacgattt gtagtgggct
    31381 tgcctaaaaa catgaacaat acaagtggac cgcgcgtaga agctagtcaa gcctacggag
    31441 caaagctaga agagtttttt ggtttaccag tagactatca ggatgaacgc ttgacaacag
    31501 tggctgctga gcgcatgttg attgaacaag cagatatcag tcgcaataag cgcaagaaag
    31561 tcattgataa gttagcagct cagctgattt tacaaaatta tttagataga aaattttaat
    31621 ataaaggaga ggctatgtca cacgatcata accacgacca cgaagaacgt gaactaatca
    31681 cactagtaga tgagcaagga aatgaaacct tgtttgaaat ccttttgaca attgatggaa
    31741 aagaagaatt tggtaaaaac tatgttcttc tagtaccagt taacgcagaa gaagacgaag
    31801 acggacaagt tgaaatccaa gcttactcat tcattgaaaa tgaagatgga acagaaggcg
    31861 aattgcaacc aatcccagaa gactcagaag acgaatggaa catgattgaa gaagtcttca
    31921 acagctttat ggaggagtaa aaacgtccgg gggacgtttt tagccctgcg ctagaaatta
    31981 gaaacgcagg tagtctggga gactgtatca gcccaactcc agaaatgggg aagagttgga
    32041 acgtccagtg aacattttta ccccatattc acattcatag tggctagtta ttagctaacc
    32101 aggtaagagg tcgggacgaa aatcctggcc ttgtttttat tagtaaccat actttaatgc
    32161 gataattgat tggacttttg tcaaggagat gtgtatgttt gaagtagaag aatggctcca
    32221 tagtcggatt ggtttgaatt ttcgatcagg tttgggccga atgcagcaag cggtggattt
    32281 gttaggaaat cctgagcagt cttaccctat tatccacgta acagggacta atgggaaagg
    32341 atctaccatt gcttttatga gggaattatt tatggggcat ggcaaaaaag ttgcgacctt
    32401 tacctcccct catatcgtct ctatcaatga ccgaatctgc attaatgggc aacctatagc
    32461 agacgcagac tttatccgtt tgactgatca ggtcaaggag atggagaaaa cgcttctgca
    32521 aactcctgcc cagttgtcct tttttgaatt gctgacctta gttgcttttc tttattttag
    32581 ggagcaagag gtggatttgg ttttattaga agtgggaatt ggtggcttac ttgacacgac
    32641 caatgtggta actggagagc ttgctgtcat cacctccatt gggcttgacc atcaagaaac
    32701 cttgggtgat agtctagaag caattgcaga gcagaaagct ggtattttca aggctggtaa
    32761 gaaggcagtg attgcgaaat tgcctccaga agctaggctt gtctgtcaga aaaaagccga
    32821 atctttagct gttaaccttt atcaggcagg tcaagatttt ttaatgctga atggtgattt
    32881 ttcaagctct ttactaaatc tttcacagct gaacataggc ttagaaggag tctatcagca
    32941 ggagaatgca gccttggcgt tgcaaacttt tcttcttttt atgggagaag gaaaggaagc
    33001 tgttgatgaa caggctgtaa gaaaggcctt ggaacagacc cattgggctg gtcgcttgga
    33061 gcgtattcgc ccacagattt acttggatgg tgctcataac ctccctgcct tgactcgctt
    33121 ggttgagttt atcaaagaaa aagagcagga aggctatcga cctcaaatcc tttttggagc
    33181 cttgaaacgg aaggattatc aagggatgtt aggttacctg actgaaaaat tgcctcaggt
    33241 ggaactcaag gtgaccggct ttgactatca gggggctttg gacgaaaggg atgtgacagg
    33301 ttacgatata gtttcttctt accgagaatt tatcagcgat tttgaagaaa gagcagatgc
    33361 tcaggatttg ctgttcgtta cagggtctct ctattttatc tcagaagtac ggggctacct
    33421 gctggaccgt gagcagataa attgaccccc ttgtttgaac ttgttatact aggggaattg
    33481 ctggttagag aaaatttctc taaattggta gcagaaagga aattcatcat gaaattaaaa
    33541 agattcacac tttctcttgc ttctctagca agttttagtc tcttagtagc ttgttcacaa
    33601 agagctcaac aggttcaaca gcctgttgct cagcagcagg tccaacagcc tgctcaacag
    33661 aataccaata ctgcaaatgc aggaggtaac caaaatcaag cggctccagt acaaaaccaa
    33721 cctgttgctc aaccgaccga tattgatggg acttatactg gtcgggatga cggagaccgt
    33781 atcactttag tggtaactgg aacgactggt acatggactg agctcgaatc tgacggggat
    33841 cagaaagtca aacaggttac atttgattca gcaaatcaac gcatgattat tggcgatgat
    33901 gtcaaaattt acactgtaaa cggtaatcaa atcgtcgtag atgatatgga tagagaccca
    33961 tcggaccaaa tcgttttaac taaataagac tatgcaagta gaaagggctg gatttttcag
    34021 cctttttact tttacctaga aaataatcat aaatacttgc cttctaccga atacctgcgt
    34081 tatactagta tcaattactt gtttttagca ttcaaactat caaggagggg atatgaaata
    34141 taggaaattt caattattga tgtccaagta tggctttagt ctttcgatta tgctacttga
    34201 actttgtctt gtttttggtc tctttcttta tttaggacgc atggctccca ttttatggat
    34261 tactgtcctc attctactga gtatcatcac aatcatttcg atagtcaacc gtaatacgac
    34321 tcctgagaat aaggtaacct ggttgttagt agcctttgtg ccagtatttg gtcccttgct
    34381 ctatctgatg tttggtgaaa ggcgattgtc caaaaaagaa atcaaacaac tgaagaagct
    34441 aggctctatg catttccaag aagcaaatag ccagctacta aaagagaaat taaaagaaag
    34501 tgacaaggca gcttatggag tcatcaagtc cttattgagt atggatacca atgctgacat
    34561 ctatgatcaa actgcctcta cattttttcc taacggagaa gctatgtgga aaaagatggt
    34621 agaagatctt aaaaaggctg agaaatttat tttcttggaa tattacatta tagaagaagg
    34681 tttgatgtgg aatcgcatac tagatatact agagcaaaag gtagctcagg gtgtagaggt
    34741 taagatgctc tatgatgata tcggctgtat ggctacttta acaggagatt atgcacatcg
    34801 acttcgtcag ctgggcatcg aggcccataa attcaataaa gttattcctc gtttgacagt
    34861 ggcttataat aacagagatc atagaaaaat attgattgtt gatggtcaga tagcctatac
    34921 tggtggggtc aatctggcag atgagtacat taaccacgtc gagagatttg gttattggaa
    34981 ggatagtgga attcgcttag acggactagc agtaaaagcc ctgacacgct tatttttgac
    35041 cacttggtac attaatcgag gagaaattag tgattttgat caatatcatt tagaaaatca
    35101 ttctatcccg agtgacggtt taaccattcc atacggaagt ggacccaagc caatttttcg
    35161 agcgcaggta gggaaaaaag tttatcagag tttaatcaat caagcaacag aatcggtcta
    35221 tattacgaca ccttatttga ttatagatta tgatttaaca gagacaatca aaaatgcagc
    35281 tatgagaggg gtcgatgttc gaattatcac cccttacata ccagataaga agttcattca
    35341 gttagtcacg agaggagctt atcccgacct tctttctgct ggtgttcgga tttatgagta
    35401 tagtccaggt tttattcata gtaagcagat gttggtagac gaagattttg cggtggtggg
    35461 gacaatcaat ctcgactacc ggagcttggt acaccattat gaaaatgcag tcttactcta
    35521 taaaactcct tctataaggg aaatcgcccg agattttcga aatatatttg cagattctca
    35581 ggaagtctat cctcattcta tcaaaacgag ctggtatcaa aagcttgtaa aagaaatcgc
    35641 ccagctattc gcccctatct tataagaaat ctagaactta ggatacaaac cagacctatt
    35701 tttcttgtct tttacgaata gaaagaaaga ggaggggaat tcatgctaac taaggaagaa
    35761 gtgaatgata tgattgagtt caaacagaca catttacacc gctttcggga aattgaaacc
    35821 tttgtgaaac tatgcaaaaa atcactcaaa cagccatcgc aagctgacaa tcctaggact
    35881 ttttgatata ctaagacaga taaattgaac aggagaaacg atatgagtgt gtatggtaga
    35941 gtagaagaag ttcataagga gaatcgtgaa cctctagaat accaaatcga acaagaatcg
    36001 catcatcgtg aatcaagtcg tcttcctttg gtgaaaattt tactatggag tacgcttgta
    36061 acggggataa ctctaggagt accgctatta ctcgacttaa tgagtgcaca agaagtgcag
    36121 gatttttatg caggttgggc gcttcatcag acagggaaga tttacagcga ctattatgga
    36181 agtcaaggtt tgctttatta tttgctgact tacgtgagtc agggcggatt tttctttgcc
    36241 atctttgagt ggttagcctt ggtagcagga ggatttttcc tttttagatc agcggacacc
    36301 ttgacagagc aaggagacca agctggacat ctggtgacta ttttttacat gctagttaca
    36361 ggtcttgctt ttggtggagg ctatgcgact cttttagcgc ttcctttctt attcgcagcc
    36421 tttagtttag ttgcggctta cctaagcaat ccaagccatg ataagggatt tgtacggatt
    36481 gggctagctt tggcaggcgg atttttcttt gctcccttat catcgctcct gtttattgct
    36541 gtagtgagtt taggcttgtt ggtctttaac cttgggcata gacgttttgt gcatgggttt
    36601 tatcagtttc ttgcagtggc tttaggtttt tcacttgtct tttatccaac tgcctactat
    36661 agtgctgcaa caggaagttt tggggatgcg attagtggta ttcgttatcc tattgacagt
    36721 attcgctttg attttacttc taaaatttta gagaatatgt ttttttatgg cttgttgtcc
    36781 cttggtttgg gatttgtggt ttgtatcttt ttaggtctct ttcaatccaa accctttaaa
    36841 ctatacgtca tttcggttcc tgcaagtctt gtggtaattt taggtttgat tttacttttc
    36901 ttttcacaag agcctctgca cgcttcttat ttgatggtcg tcttccctgt tttcctactt
    36961 ttattggtaa ccaatattaa gagtcaacag agggggcgta gtgctagaag aagccgaaga
    37021 gaaacgccag ttagcctatg gagtcgtttc ttcaaaggaa atctatatct gctagttttt
    37081 gggtttgtct atcttttgtc tgttcctttt ttgatgaagt ttgtccttta tccagtacct
    37141 tatcaagaac gtaatcgtct tgctgatttg gtaaaagagg agacaaatac ggaagatgct
    37201 atctatgcat gggatgatac tgcgactctt tatcgtaaga gtgagcgctt gtcgccatcg
    37261 gcgattttgt ccccgttgca ctatacagca actgaagaaa atcgtaataa gttacttaat
    37321 gacttgaaag aaaaacaacc taaggtgatt gtggtaaatg acaaggtggt agtctggtct
    37381 gaagtggaaa cactcttaaa agaaaattac caacaagtaa agactgatta ctcagagttt
    37441 aaagtctata aaattaaata accaaatcaa tatcttgtgt atttttaaaa attttaggat
    37501 ttttaacaca agatattgat ttttcttttt agagtggtat aatacttttt agaaagaaca
    37561 ttttagaaaa gagcatgcat atgattgcac tagaagaaaa aattacaatt ttgccaactc
    37621 tcttcgtcga gaaacgagat gggagacgtg ttgtatttga tgtggacaag attgacaagg
    37681 ctctccacaa ggcggctgac aaggttatgg atgtgacacc cctggttgaa aaacgcctca
    37741 atgatctgac tgagcgaatt attacagaaa ttcatagtcg ctttccacag ggaattaaga
    37801 tttacgaaat tcaaaatatc gtagaacatg aactccttga agccaaagaa tatgcgctgg
    37861 ctgaggagta tattacttat cggacacaga gggattttga gcgctcaaaa gcgacggata
    37921 tcaactttag tattcataaa cttctcaaca aagaccagac agttgtcaat gaaaatgcta
    37981 ataaagacag tgatgtcttt aacactcagc gtgatttgac agcagggatt gttgggaaat
    38041 caatcggact gcaaatgctt cctaagcacg tagccaatgc ccaccaaaag ggggatatcc
    38101 actatcacga tttggactac agtccctata cccctatgac caactgctgt ttgattgatt
    38161 ttaagggtat gttggaaaat ggttttaaga ttggaaatgc agaggtagag agtcccaagt
    38221 ctatccagac tgcgacagca cagatttctc aaatcattgc caacgttgct tctagccagt
    38281 acggtggctg ttcagctgac cgtatcgatg aaattttggc gccttatgca gagaagaatt
    38341 atcaaaaaca tctcaaagat gcagaagagt gggtattgcc tgaaaaacgg gaagattacg
    38401 cttggaagaa aacgcaaaag gacatctacg atgccatgca atctcttgag tatgaaatca
    38461 atactctctt cacttcaaat ggacaaacac cttttacttc gttaggtttt ggtctgggaa
    38521 ccagtcgttt tgaacgagaa attcaaaaag ctattttaaa cattcgcatc aagggtcttg
    38581 gttcagaaca ccgtacggct atctttccta aacttatttt cactctgaaa agaggcctta
    38641 atttagagga aggaactccc aactacgaca tcaagcagtt ggctcttgag tgtgcaacca
    38701 aacggatgta tccagatgtt ttatcttacg ataagattgt tgacttgaca ggatccttca
    38761 aggtgcctat gggttgccgt tctttcctcc aaggatggaa ggatgaaaat ggtgtagaag
    38821 tcaattcagg tcgcatgaat ctgggtgttg tgacggttaa tctgcctcgt attgctcttg
    38881 agtctgaagg tgatatgaat aagttctggg aaatcttcaa cgagcgaatg aatatcgcag
    38941 aagatgctct tgtttaccgt gtcgaacgca ctaaagaggc gacaccagca aatgctccta
    39001 ttctttatca gtacggtgct tttggccatc gtctaggtaa agaagaaagt gttgaccagc
    39061 tctttaagaa tcgtcgtgct accgtttcgc tgggctatat cggcttgtat gaagtagcga
    39121 cagttttctt tggtaacagc tgggaaagta atccagatgc taaggaattc acgctagaca
    39181 tcattcacga tatgaaacgc cgtgtagaag agtggtcaga ccaatatggc taccatttct
    39241 ctatctactc aacaccatcc gaaagtctga cagaccgttt ctgccgacta gatatagaca
    39301 agtttggctc tattcctgat atcacagaca aggaatacta caccaactct ttccactacg
    39361 atgttcgtaa aaatccaaca ccgtttgaaa aattggactt tgagaaagtc tatccagaag
    39421 caggtgcgtc aggtggtttc atccattatt gtgagtatcc agtccttcag caaaatccaa
    39481 aggccttgga agctgtctgg gattatgctt atgaccgtgt aggctatcta ggcaccaata
    39541 ctccgattga ccgttgctac aagtgtgact ttgaagggga ttttgaacca actgagagag
    39601 ggtttgcttg tccaaactgt ggcaatagcg accctaaaac agtagatgtg gtgaagcgaa
    39661 cttgtggcta cctaggtaat cctcaagcaa gaccgatggt caacgggcgt cacaaggaaa
    39721 tcgctgcgcg tgtcaaacat atgaatggtt caacgattaa aatagctggg catcaagtaa
    39781 caaattagaa agaaatgaaa tgggaaaata tcaactagac gataaggggc gcgcacaagt
    39841 gacccgttat cacgagaaac actctaaagg tggagctggt aagaaagaac gcttgcttag
    39901 cttcagagaa caatttttaa acaagaacaa gaaaaaataa aagtgagagc cagctctcgc
    39961 ttttctcata gtgggaggta aggatggaat tacgcagacc aagattagcg gataagaaag
    40021 ctgttttaga tatgatgaca gagtttgaaa aatttcagtc gcctcacgac ggcggtttct
    40081 gggatacaga gaactttgtg tatgaagact ggttagaaag caatcaggaa caggaaatgg
    40141 gaattaatct gcctgaagga tgggttcctg caattcagtt agtggctttt tctgagaaag
    40201 gtcaagcagt tggatttctt aatctccggt tgcgcctcag taactttcta ctagaagaag
    40261 gtgggcacat tggctactcc atccgtccat ctgaaagagg caagggttat gcaaaagaga
    40321 ctctccgtca gggcttgcaa gttgctaagg aaaagaacat caagaaagct ctggtgacct
    40381 gtagcgtgaa taatcctgct aacagagcag tcattctagc aaatggtgga atatttgagg
    40441 atgctcgcaa tggagtcgag cgttattgga tagaggtagc gaatgaataa tccaaaacca
    40501 caagaatgga aaagcgagga acttagtcaa ggtcgtatca ttgactacaa ggcctttaac
    40561 tttgttgatg gcgaaggcgt gcgtaactct ctctatgtag caggctgtat gtttcactgc
    40621 gagggatgtt ataatgttgc gacttggtct tttaatgctg gcattcccta tacagcagaa
    40681 ttagaagagc agatcatggc agaccttgcc caaccctatg ttcaaggctt gactttgctg
    40741 ggaggggagc cttttctcaa tactggcatt ctcttgcctc tagttaaacg catccgaaag
    40801 gaattgccag acaaggacat ttggtcctgg acgggctaca cttgggaaga aatgatgttg
    40861 gaaactccag ataaactgga actcttgtca ctgattgaca ttcttgtcga tggaagatat
    40921 gatcgaacta agagaaatct tatgctccag tttcgaggtt cgtccaacca acgaattatc
    40981 gatgtgcaaa aatcgctcaa aagtgggcaa gtagtgattt gggacaagct caatgacgga
    41041 aaagaaagct atgaacaggt gaagagagaa tgaagaaaaa agacttagta gaccaactag
    41101 tctcagagat cgagacgggg aaagtcagga cactgggaat atacggtcat ggagcttcag
    41161 gtaaatcaac ctttgcacag gaattgtacc aagctttaga ttctactaca gtaaatttgc
    41221 tagaaacaga tccctatatc acctccggac gctatttggt agtacccaag gacgcgccga
    41281 atcaaaaggt gacagccagt ctgccagtgg cgcatgaact ggagagtttg cagagagata
    41341 tccttgcctt gcaggcgggt atggatgtct tgacaattga agaaccttgg aaggctagtg
    41401 aggtcttgtc tggagccaaa ccaattttga ttgtcgaagg gatgtctgtt ggctttctac
    41461 ccaaggaact ctttgaaaaa accatctgtt tctacacgga tgaggagacc gaattaaagc
    41521 gacgccttgc tagagatacg actgtgagaa atcgcgatgc atcctttata ttggctagcc
    41581 atcagatgag acgggagcag tatctgcgat actataaaga aactgagtct aaggcggata
    41641 tcttagtgga ccaatcagaa gataaatttg atgtcaagag gacttaactt atgtatagaa
    41701 gaaatataga agaaaatccc taattttaga aagaaaaagt aggaaaacag tttcatccca
    41761 aaaaaacgaa aaaacagcaa caaatccctt gcaatcgcag gggctttgtg ttattctatt
    41821 atggtgctgt aaattacagc cttagttttg atgcaagagg ttgcgacacg ctcggttgca
    41881 ttgccacgca acaccgcgtc ggttttcttg tggagctagc ctattatctt aaatagacga
    41941 aaaggagaaa aagatggcaa acaaaaaaat ccgtatccgt ttgaaagctt acgaacaccg
    42001 tacgcttgac acagcggctg caaaaatcgt agaatcagct actcgtacag gtgcacaagt
    42061 tgcgggtcca atcccacttc caactgaacg tagcctctac acaatcattc gtgcgactca
    42121 caaatacaaa gactctcgcg aacaatttga aatgcgtaca cacaaacgtt tgatcgatat
    42181 cgttaaccca actcaaaaaa cagttgatgc cttgatgaaa ttggatcttc caagtggtgt
    42241 aaacgtagaa atcaaacttt aatctaaaat ataaaagagc agaggctggt gtttcaatct
    42301 aattgaacac gggctaaact cggtgtgaaa aagataaact tcctcgcgtc tgctagacac
    42361 tgtgtcagtt tcctattttc acgttgagtt tgacgccctt tgtatcttag acttgagcat
    42421 aaaaaacgct cgttaaaaac tttttgaata aaaatataga aaaggaacta ttttctcatg
    42481 acaaaaggaa tcttagggaa aaaagtggga atgactcaaa tcttcactga agctggcgaa
    42541 ttgatccctg taacagttat tgaagcaact ccaaacgttg ttcttcaagt taaaactgtt
    42601 gaaacagacg gatacaacgc tatccaagtt ggtttcgatg acaaacgcga agtattgagc
    42661 aacaaacctg ctaaaggaca tgtagcgaaa gctaacacgg ctcctaagcg cttcattcgt
    42721 gaattcaaaa acgttgaagg cttggaagtt ggtgctgaaa ttacagttga aacattcgca
    42781 gctggagacg ttgttgacgt aacgggtact tctaaaggta aaggtttcca aggtgttatc
    42841 aaacgccacg gacaatcacg tggaccaatg gctcacggtt ctcgttacca ccgtcgtcca
    42901 ggttctatgg ggcctgttgc acctaaccgc gtattcaaag gtaaaaacct tgcaggacgt
    42961 atgggtggcg accgcgtaac aattcaaaac cttgaagttg tacaagttgt tccagaaaag
    43021 aacgttatcc ttatcaaagg taacgtacca ggtgctaaga aatctcttat cactatcaaa
    43081 tcagcagtta aagctggtaa ataataaaga aaggggaaat cagtcacaat ggcaaacgta
    43141 acattatttg accaaactgg taaagaagct ggccaagttg ttcttagcga tgcagtattt
    43201 ggtatcgaac caaatgaatc agttgtgttt gatgtaatca tcagccaacg cgcaagcctt
    43261 cgtcaaggaa cacacgctgt taaaaaccgc tctgcagtat caggtggtgg acgcaaacca
    43321 tggcgtcaaa aaggaactgg acgtgctcgt caaggttcta tccgctcacc acaatggcgt
    43381 ggtggtggtg ttgtcttcgg accaactcca cgttcatacg gctacaaact tccacaaaaa
    43441 gttcgtcgcc tagctcttaa atcagtttac tctgaaaaag ttgctgaaaa caaattcgta
    43501 gctgtagacg ctctttcatt tacagctcca aaaactgctg aatttgcaaa agttcttgca
    43561 gcattgagca tcgattctaa agttcttgtt atccttgaag aaggaaatga attcgcagct
    43621 ctttcagctc gtaaccttcc aaacgtgaaa gttgcaactg ctacaactgc aagtgttctt
    43681 gacatcgcaa atagcgacaa acttcttgtc acacaagcag ctatctctaa aatcgaggag
    43741 gttcttgcat aatgaatttg tatgatgtta tcaaaaaacc tgtcatcact gaaagctcaa
    43801 tggctcaact tgaagcagga aaatatgtat ttgaagttga cactcgtgca cacaaacttt
    43861 tgatcaagca agctgttgaa gctgctttcg aaggtgttaa agttgccaat gttaacacaa
    43921 tcaacgtaaa accaaaagct aaacgtgttg gacgttacac tggttttact aacaaaacta
    43981 aaaaagctat catcacactt acagctgatt caaaagcaat cgagttgttt gctgctgaag
    44041 ctgaataatc taaggaggaa atatcgtggg aattcgtgtt tataaaccaa caacaaacgg
    44101 tcgccgtaat atgacttctt tggatttcgc tgaaatcaca acaagcactc ctgaaaaatc
    44161 attgcttgtt gcattgaaga gcaaggctgg tcgtaacaac aacggtcgta tcacagttcg
    44221 tcaccaaggt ggtggacaca aacgtttcta ccgtttggtt gacttcaaac gtaacaaaga
    44281 caacgttgaa gcagttgtta aaacaatcga gtacgatcca aaccgttctg caaacatcgc
    44341 tcttgtacac tacactgatg gtgtgaaagc atacatcatc gctccaaaag gtcttgaagt
    44401 aggtcaacgt atcgtttcag gtccagaagc agatatcaaa gtcggaaacg ctcttccact
    44461 tgctaacatc ccagttggta ctttgattca caacatcgag ttgaaaccag gtcgtggtgg
    44521 tgaattggta cgtgctgctg gtgcctctgc tcaagtattg ggttctgaag gtaaatacgt
    44581 tcttgttcgt cttcaatcag gtgaagttcg tatgattctt ggaacttgcc gtgctacagt
    44641 tggtgttgtc ggaaacgaac aacatggact tgtaaacctt ggtaaagcag gacgtagccg
    44701 ttggaaaggt atccgcccaa cagttcgtgg ttctgtaatg aaccctaacg atcacccaca
    44761 cggtggtggt gaaggtaaag caccagttgg tcgtaaagca ccatctactc catggggcaa
    44821 acctgctctt ggtcttaaaa ctcgtaacaa gaaagcgaaa tctgacaaac ttatcgttcg
    44881 tcgtcgcaac gagaaataat atttaagcaa ctagtaaatc cgccagctcg gtagcgctcc
    44941 ataggagtgc aagccgctgt ggtacaacat ttaaaggaga aaatataaaa atgggacgca
    45001 gtcttaaaaa aggacctttc gtcgatgagc atttgatgaa aaaagttgaa gctcaagcta
    45061 acgacgaaaa gaaaaaagtt attaaaactt ggtcacgtcg ttcaacgatc ttcccaagtt
    45121 tcattggtta cactattgca gtttatgacg gacgtaaaca cgtacctgtt tacatccaag
    45181 aagacatggt aggccacaaa cttggtgaat ttgcaccaac tcgtacttac aaaggtcacg
    45241 ctgcagacga caagaaaaca cgtagaaaat aaggagaaca taaatggcag aaattacttc
    45301 agctaaagca atggctcgta cagtacgtgt ttcacctcgt aaatcacgtc ttgttcttga
    45361 taacatccgt ggtaaaagcg tagccgatgc aatcgcaatc ttgacattca ctccaaacaa
    45421 agctgctgaa atcatcttga aagttttgaa ctcagctgta gctaacgctg aaaacaactt
    45481 tggtttggat aaagctaatt tggtagtatc tgaagcattc gcaaacgaag gaccaactat
    45541 gaaacgtttc cgtccacgtg cgaaaggttc agcttcacca atcaacaaac gtacagctca
    45601 catcactgta gctgttgcag aaaaataagg aggtaaaatc gtgggtcaaa aagtacatcc
    45661 aattggtatg cgtgtcggca tcatccgtga ttgggatgcc aaatggtatg ctgaaaaaga
    45721 atacgcggat taccttcatg aagatcttgc aatccgtaaa ttcgttcaaa aagaacttgc
    45781 tgacgcagca gtttcaacta ttgaaatcga acgcgcagta aacaaagtta acgtttcact
    45841 tcacactgct aaaccaggta tggttatcgg taaaggtggt gctaacgttg atgcactccg
    45901 tgcaaaactt aacaaattga ctggaaaaca agtacacatc aacatcatcg aaatcaaaca
    45961 acctgatttg gatgctcacc ttgtaggtga aggaattgct cgtcaattgg agcaacgtgt
    46021 tgctttccgt cgtgcacaaa aacaagcaat ccaacgtgca atgcgtgctg gagctaaagg
    46081 aatcaaaact caagtatcag gtcgtttgaa cggtgcagat atcgcccgtg ctgaaggata
    46141 ctctgaagga actgttccgc ttcacacact tcgtgcagat atcgattacg cttgggaaga
    46201 agcagatact acatacggta aacttggtgt taaagtatgg atctaccgtg gtgaagttct
    46261 tccagctcgt aaaaacacta aaggaggtaa ataaccaatg ttagtaccta aacgtgttaa
    46321 acaccgtcgt gagttccgtg gaaaaatgcg cggtgaagca aaaggtggaa aagaagtagc
    46381 attcggtgaa tacggtcttc aagctacaac tagccactgg atcactaacc gccaaatcga
    46441 agctgctcgt atcgccatga ctcgttacat gaaacgtggt ggtaaagttt ggattaaaat
    46501 cttcccacac aaatcataca ctgctaaagc tatcggtgtg cgtatgggat ctggtaaagg
    46561 ggcacctgaa ggttgggtag caccagttaa acgtggtaaa gtgatgttcg aaatcgctgg
    46621 tgtatctgaa gagattgcac gtgaagcgct tcgacttgct agccacaaat tgccagttaa
    46681 atgtaaattc gtaaaacgtg aagcagaata aggagaaggc atgaaactta atgaagtaaa
    46741 agaatttgtt aaagaacttc gtggtctttc tcaagaagaa ctcgcgaagc gcgaaaacga
    46801 attgaaaaaa gaattgtttg aacttcgttt ccaagctgct actggtcaat tggaacaaac
    46861 agctcgcttg aaagaagtta aaaaacaaat cgctcgtatc aaaacagttc aatctgaagc
    46921 gaaataatag actagggaag gagaaatttc aatggaacgc aataatcgta aagttcttgt
    46981 tggacgtgtt gtatctgaca aaatggacaa gacaatcaca gttgtagttg aaacaaaacg
    47041 taaccaccca gtctatggta aacgtattaa ctactctaaa aaatacaaag ctcatgatga
    47101 aaacaatgtt gccaaagaag gcgatatcgt acgtatcatg gaaactcgcc cgctttcagc
    47161 tacaaaacgt ttccgtcttg tagaagttgt tgaagaagcg gtcatcatct aatcaaacct
    47221 gaaaggagaa aactgaaatg attcaaacag aaactcgttt gaaagtcgca gacaacagcg
    47281 gtgctcgcga aatcttgact atcaaagttc ttggtggttc aggacgtaaa tttgcaaaca
    47341 tcggtgatgt tatcgtggca tctgtaaaac aagctactcc tggtggtgcg gttaaaaaag
    47401 gtgacgttgt taaagcagtt atcgttcgta ctaaatcagg tgctcgtcgt gctgatggtt
    47461 catacatcaa atttgacgaa aacgcagcag ttatcatccg tgaagacaaa actcctcgcg
    47521 gaacacgtat ctttggccca gttgcacgtg aattgcgtga aggtggcttc atgaagatcg
    47581 tgtcacttgc tccagaagta ctttaatttt taggaacaaa ctagtcccct agcttcaagc
    47641 tagggtgccc ttatgggcgt aagaaaaatc aaggagaaac ctaatgtttg taaaaaaagg
    47701 cgacaaagtt cgcgtaatcg ctggtaaaga taagggaaca gaagctgttg tccttactgc
    47761 ccttccaaaa gtaaacaaag ttatcgttga aggtgttaac attgttaaga aacaccaacg
    47821 tccaactaac gagcttcctc aaggtggtat catcgagaaa gaagcagcta tccacgtatc
    47881 aaatgttcaa gttttggaca aaaatggtgt agctggtcgt gttggttaca aatttgtaga
    47941 cggtaaaaaa gttcgctaca acaaaaaatc aggcgaagtg cttgattaat cacgaaggaa
    48001 aggagaagta taatggcaaa tcgtttaaaa gaaaaatatc ttaatgaagt agttcctgct
    48061 ttgacagaac aattcaacta ctcatcagtg atggctgtgc ctaaagtaga taagattgtt
    48121 ttgaacatgg gtgttggtga agctgtatca aacgctaaaa gccttgaaaa agctgctgaa
    48181 gaattggcac ttatctcagg tcaaaaacca cttatcacta aagctaaaaa atcaatcgcc
    48241 ggcttccgtc ttcgtgaagg tgttgcgatc ggtgcaaaag ttacccttcg tggtgaacgt
    48301 atgtacgaat tcttggataa attggtatca gtttcacttc cacgtgtacg tgacttccac
    48361 ggtgtcccaa caaaatcatt tgatggacgc gggaactata cacttggtgt gaaagaacaa
    48421 ttaatcttcc cagaaatcaa cttcgatgac gttgacaaaa ctcgtggtct tgacatcgtt
    48481 atcgtaacaa ctgctaacac tgacgaagag tcacgtgcat tgcttacagg ccttggaatg
    48541 ccttttgcaa aataatatag gaggtaaatc taatggctaa aaaatcaatg gtagctagag
    48601 aggctaaacg ccaaaaaatt gttgaccgtt atgctgaaaa acgtgctgca ttaaaggcgg
    48661 caggggacta cgaaggttta tctaaattac ctcgcaacgc ctcaccgact cgtttacata
    48721 atcgttgtag agttacgggg cgcccacatt cagtttaccg caaatttggt ctgagtcgta
    48781 tcgcttttcg cgaacttgcg cataaaggtc aaattcctgg tgtaacaaaa gcatcttggt
    48841 aatatcatga tacaaagagc gtaacaacca cagcgaaaat aggaaatttg gtgagggagc
    48901 gatgctccaa aacaaattta tcttttttgc acaggttgta gctcgtgttc aaataagagt
    48961 tctctcgttt gaatgtgtca atactatctg agcccagctc aatcattaac tagcaagtgc
    49021 aacttgcaaa ctactagtaa gaggagaaaa acaaaatggt tatgactgac ccaatcgcag
    49081 acttcctaac tcgtattcgt aatgctaacc aagctaaaca cgaagtactt gaagtacctg
    49141 catcaaacat caaaaaaggg attgctgaaa tccttaaacg cgaaggtttt gtaaaaaacg
    49201 ttgaaatcat tgaagatgac aaacaaggcg tcatccgtgt atttcttaaa tacggaccaa
    49261 atggtgagaa agttatcact aacttgaaac gtgtttctaa accaggactt cgtgtctaca
    49321 aaaaacgtga agaccttcca aaagttctta acggacttgg aattgccatc ctttcaactt
    49381 ctgaaggttt gcttactgat aaagaagcac gccaaaagaa tgttggtggt gaggttatcg
    49441 cttacgtttg gtaaaatcaa gatacaaagc tcgtaaagaa caaagcaaaa ttaggaagtt
    49501 ggagaagttt gtttacaaac aagccaactt atctattttg cacagttctt agagcgtgtt
    49561 cagttcagct cttgaactaa ataagtatct gaaccccgtg aaaactggcc gttctggcct
    49621 gacaatttaa caggagaaaa taaacatgtc acgtattggt aataaagtta tcgtgttgcc
    49681 tgctggtgtt gaactcgcta acaatgacaa cgttgtaact gtaaaaggac ctaaaggaga
    49741 acttactcgt gagttctcaa aagatattga aatccgtgtg gaaggtactg aaataactct
    49801 tcaccgtcca aacgattcaa aagaaatgaa aactatccac ggaactactc gtgccctttt
    49861 gaacaacatg gttgttggtg tatcagaagg attcaagaaa gaacttgaaa tgcgtggggt
    49921 tggttaccgt gcacagcttc aaggatctaa acttgttttg gctgttggta aatctcatcc
    49981 agacgaagtt gaagctccag aaggaattac ttttgaactt ccaaacccaa caacaatcgt
    50041 tgttagcgga atttcaaaag aagtagttgg tcaaacagct gcttacgtac gtagccttcg
    50101 ttcaccagaa ccatataaag gtaaaggtat ccgttacgtt ggtgaattcg ttcgccgtaa
    50161 agaaggtaaa acaggtaaat aatgttgagt ggttgatcat caaccaccaa cctattttcc
    50221 aactttgtgc atagcacacg atttaaaact aaagaggtga aaactgtgat ttcaaaacca
    50281 gataaaaaca aactccgcca aaaacgccac cgtcgcgttc gcggaaaact ctctggaact
    50341 gctgatcgcc cacgtttgaa cgtattccgt tctaatacag gcatctacgc tcaagtgatt
    50401 gatgacgtag cgggtgtaac gctcgcaagt gcttcaactc ttgataaaga agtttcaaaa
    50461 ggaactaaaa ctgaacaagc cgttgctgtc ggtaaactcg ttgcagaacg tgcaaacgct
    50521 aaaggtattt cagaagtggt gttcgaccgc ggtggatatc tatatcacgg acgtgtgaaa
    50581 gctttggctg atgcagctcg tgaaaacgga ttgaaattct aataggagga cactagaaaa
    50641 tggcatttaa agacaatgca gttgaattag aagaacgcgt agttgctgtc aaccgtgtta
    50701 caaaagttgt taaaggtgga cgtcgtcttc gtttcgcagc tcttgttgtt gttggtgacc
    50761 acaatggtcg cgtaggattt ggtactggta aagctcaaga agttccagaa gcaatccgta
    50821 aagcagtaga tgatgctaag aaaaacttga tcgaagttcc tatggttgga acaacaatcc
    50881 cacacgaagt tctttcagaa ttcggtggag ctaaagtatt gttgaaacct gctgtagaag
    50941 gttctggagt tgccgctggt ggtgcagttc gtgccgttgt ggaattggca ggtgtggcag
    51001 atattacatc taaatcactt ggttctaaca ctccaatcaa cattgttcgt gcaactgttg
    51061 aaggtttgaa acaattgaaa cgcgctgaag aaattgctgc ccttcgtggt atttcagttt
    51121 ctgatttggc ataagaaagg ggataaaatg gctcaaatta aaattacttt gactaagtct
    51181 ccaatcggac gcattccatc acaacgtaaa actgttgtag cacttggact tggcaaattg
    51241 aacagctctg ttattaaaga agataacgct gctatccgtg gtatgattac agcagtatct
    51301 cacttagtaa cagttgaaga agtaaactaa tgaagtttta ggggatgtgc actgtaccat
    51361 cccctaaaac tagatatagt catctatgat gacatcgtat aggcgagttg atgggggaga
    51421 caaccttttc tcccttatcg gcgctagcat tttacaaaag aggagaaaat aaaaatgaaa
    51481 cttcatgaat tgaaacctgc agaaggttct cgtaaagtac gtaaccgcgt tggtcgtggt
    51541 acttcatcag gtaacggtaa aacatctggt cgtggtcaaa aaggtcaaaa agctcgtagc
    51601 ggtggcggag ttcgccttgg ttttgaaggt ggacaaactc cattgttccg tcgtcttcca
    51661 aaacgtggat tcactaacat caacgctaaa gaatacgcaa ttgtgaacct tgaccaattg
    51721 aacgtctttg aagatggtgc tgaagtaact ccagttgttc ttatcgaagc aggaattgtt
    51781 aaagctgaaa agtcaggtat taaaattctt ggtaacggtg agttgactaa gaaattgact
    51841 gtgaaagcag ctaaattctc taaatcagct gaagaagcta tcactgctaa aggtggttca
    51901 gtagaagtca tctaagagag gtgacctatg ttttttaaat tattaagaga agctcttaaa
    51961 gtcaagcagg ttcgatcaaa aattttattt acaattttta tcgttttggt ctttcgtatc
    52021 ggaactagca ttacagttcc tggtgtgaat gccaatagct tgaatgcttt aagtggatta
    52081 tccttcttaa acatgttgag cttggtgtcg gggaatgccc taaaaaactt ttcgattttt
    52141 gccctaggag ttagtcccta tatcaccgct tctattgttg tccaactctt gcaaatggat
    52201 attttaccca agtttgtaga gtggggtaaa caaggggaag taggtcgaag aaaattgaat
    52261 caagctactc gttatattgc tctagttctc gcttttgtgc aatctatcgg gattacagct
    52321 ggttttaata ccttggctgg agctcaattg attaaaactg ctttaactcc acaagttttt
    52381 ctgacgattg gtatcatctt aacagctggt agtatgattg tcacttggtt gggtgagcaa
    52441 attacagata agggatacgg aaacggtgtt tccatgatta tctttgccgg gattgtttcc
    52501 tcaattccag agatgattca gggcatctat gtggactact ttgtgaacgt cccaagtagc
    52561 cgtatcactt catctatcat tttcgtaatc attttgatta ttactgtatt gttgattatt
    52621 tactttacaa cttatgttca acaagcagaa tacaaaattc caatccaata tactaaggtt
    52681 gcacaaggtg ctccatctag ctcttacctt ccgttaaagg taaaccctgc tggagttatc
    52741 cctgttatct ttgccagttc gattactgca gcgcctgcgg ctattcttca gtttttgagt
    52801 gccacaggtc atgattgggc ttgggtaagg gtagcacaag agatgttggc aactacttct
    52861 ccaactggta ttgccatgta tgctttgttg attattctct ttacattctt ctatacgttt
    52921 gtacagatta atcctgaaaa agcagcagag agcctacaaa agagtggtgc ctatatccat
    52981 ggagttcgtc ctggtaaagg tacagaagaa tatatgtcta aacttcttcg tcgtcttgca
    53041 actgttggtt ccctcttcct tggtgtgatt tccattttac cgattgcagc taaagatgta
    53101 tttggtcttt ctgatgttgt tgcctttggt ggaacaagtc tcttgatcat tatctctaca
    53161 ggtatcgaag gaatcaagca attggaaggt tacctattga aacgtaagta tgttggtttc
    53221 atggacagaa cagaataaaa gtatttactg aatcagtaaa tactgaggga gtggaggttt
    53281 aaactctgac atttgtaaga gttggatctc ccctcttcta ttttgttttt aaataggggt
    53341 gaaaagactt tttgcttcta tttaaaaata aaataaggag atcaaatcat gaatcttttg
    53401 attatgggct tacctggtgc aggtaaggga actcaagcag caaaaatcgt agaacaattc
    53461 catgttgcac atatctcaac aggtgatatg ttccgcgctg caatggcaaa tcaaactgaa
    53521 atgggtgttc ttgctaagtc atatattgac aagggtgaat tggttcctga cgaagttaca
    53581 aatggaatcg taaaagaacg cctttcacaa gatgatatta aagaaacagg attcttattg
    53641 gatggttacc cacgtacaat tgaacaagct catgccttgg acaaaacatt ggctgaactt
    53701 ggcattgaac tagaaggtat tatcaatatt gaagtgaacc ctgacagcct cttggaacgt
    53761 ttgagtggcc gtatcatcca ccgcgtaact ggagaaactt tccacaaggt ctttaaccca
    53821 ccagttgact ataaagaaga agattactac caacgtgaag atgataagcc tgagacagta
    53881 aaacgtcgtt tggatgttaa tattgctcaa ggagaaccaa tcattgctca ctaccgtgcc
    53941 aaaggtttgg ttcatgacat cgaaggtaat caagatatca atgatgtctt ctcagatatt
    54001 gaaaaagtat tgacaaattt gaaataaagc gtttttcaca cttgcaaaaa tccgctacaa
    54061 atgttatact gaaatagtct gacttataat tgttgtctct gtgtctagag gcatcgaatc
    54121 gaaatttatg gaggtgcttt tgcgtggcaa aagacgatgt gattgaagtt gaaggcaaag
    54181 tagttgatac aatgccgaat gcaatgttta cggttgaact tgaaaatgga catcagattt
    54241 tagcaacagt ttctggtaaa attcgtaaaa actatattcg tattttagcg ggagatcgtg
    54301 ttactgtcga aatgagtcca tatgacttga cacgtggacg tatcacttac cgctttaaat
    54361 aatcgaaaaa cttggaggga taagaaatga aagtaagacc atcggtcaaa ccaatttgcg
    54421 aatactgtaa agttattcgt cgtaatggtc gtgttatggt aatttgccca gcaaatccaa
    54481 aacacaaaca acgtcaagga taagatagaa aggagaaaac atggctcgta ttgctggagt
    54541 tgatattcca aatgacaaac gcgtagtaat ctcattgact tatgtttatg gtatcggact
    54601 tgcaacatct aagaaaattt tggctgctgc tggaatctca gaagatgttc gtgtacgtga
    54661 tcttacatca gatcaagaag atgctatccg tcgtgaagtg gatgcaatca aagttgaagg
    54721 tgaccttcgt cgtgaagtaa acttgaacat caaacgtttg atggaaatcg gttcataccg
    54781 tggtatccgt caccgtcgtg gacttcctgt ccgtggacaa aatactaaaa acaacgctcg
    54841 cactcgtaaa ggtaaagctg ttgcgattgc tggtaagaaa aaataatata ggaggtaaaa
    54901 gtcttggcta aaccaacacg taaacgtcgt gtgaaaaaga atatcgaatc tggtattgct
    54961 catattcacg ctacatttaa taacactatt gttatgatta ctgatgtgca tggtaatgca
    55021 attgcttggt catcagctgg tgctcttggt ttcaaaggtt ctcgtaaatc tacaccattc
    55081 gctgctcaaa tggcttctga agctgctgct aaatctgcac aagaacacgg tcttaaatca
    55141 gttgaagtta ctgtaaaagg tccaggttct ggtcgtgagt cagctattcg tgcgcttgct
    55201 gccgctggtc ttgaagtaac agcaattcgt gatgtgactc cagtgccaca caatggtgct
    55261 cgtcctccaa aacgtcgccg tgtataatca tcgcattaca ctgcttttcg tttaagaggg
    55321 agtaactaaa tgatcgagtt tgaaaaacca aatataacaa aaattgatga aaataaagat
    55381 tatggcaagt ttgtaatcga accacttgaa cgtggctacg gtacaactct tggtaactct
    55441 cttcgtcgtg tacttctagc ttctctacca ggagcagctg tgacatctat caacattgat
    55501 ggtgtgttac atgagtttga cacagttcca ggtgttcgtg aagacgtgat gcaaatcatt
    55561 ctgaacatta aaggaattgc agtgaaatcg tacgttgaag acgaaaaaat catcgaactg
    55621 gatgttgaag gtcctgctga agtaacagct ggtgacattt tgacagatag cgatattgaa
    55681 attgtaaatc cagatcatta tctctttaca atcggtgaag gttcttctct aaaagcgact
    55741 atgactgtta acagtggtcg tggatatgta cctgctgatg aaaataaaaa ggataatgca
    55801 ccagttggaa cacttgctgt agattctatt tatacaccag ttacaaaagt caactatcaa
    55861 gtggaacctg ctcgtgtagg tagcaatgat ggtttcgaca aattaaccct tgaaatcttg
    55921 acaaatggaa caattattcc agaagatgct ttagggcttt cagcacgtat tttgacagaa
    55981 catcttgatt tgtttacaaa tcttactgag attgctaagt caactgaagt gatgaaagaa
    56041 gctgatactg aatctgacaa ccgtatttta gatcgtacga ttgaggaact ggacttgtct
    56101 gtgcgttcat acaactgttt aaaacgtgcc ggtatcaata ctgtgcatga tttgacagaa
    56161 aaatctgaag cagagatgat gaaagtacga aatcttggac gcaagagttt ggaagaagtg
    56221 aaactcaaac tcattgattt gggtcttgga ttaaaagata aataaaggag gaatacatgg
    56281 cttaccgtaa actaggacgc actagctcac aacgtaaagc aatgcttcgc gatttgacaa
    56341 ctgacctttt gatcaacgaa tcaatcgtga caactgaagc tcgtgctaaa gaaatccgta
    56401 aaactgttga aaaaatgatt actctaggta aacgtggtga tttgcatgca cgtcgtcaag
    56461 cagctgcttt cgtacgtaat gaaatcgcat ctgaaaacta tgatgaagca actgataagt
    56521 acacttctac tacagcactt caaaaattgt tctcagaaat cgcacctcgt tatgctgaac
    56581 gtaacggtgg atacactcgt atccttaaaa ctgaaccacg tcgtggtgat gcagcgccaa
    56641 tggcgatcat cgaattagta taaaatcatc aattttgttg agtgttatga tgatggagtc
    56701 ttgtgctctt agtctagctc tggtctaccg ctaggatttc ggtcctagcg ggaacactca
    56761 tcataagttg ggatagtaga cgcttgttta cgaaattgtt tttttcttaa gaacaacttc
    56821 gtaagcaggc gtttttgagt attttcgtta gaattatgct atactatttg aaaagaatcc
    56881 tgtttaatgt taaggtttct tattttaaga agaattggag tttacttatg aaagcgatta
    56941 taactgttgt tggtaaagat aaatctggaa ttgttgcagg tgtttctggt aaaattgcag
    57001 aattaggatt gaatattgac gatatctctc aaactgtatt ggatgaatat tttacgatga
    57061 tggctgttgt atctagtgat gaaaagcaag attttaccta tcttcgtaat gaatttgaag
    57121 cttttgggca aactttgaat gtaaaaatca atattcagag tgcagcgatt ttcgaagcta
    57181 tgtataatat ctaggaggtc atcatggata ttagacaagt tactgaaacc atcgccatga
    57241 ttgaggagca aaacttcgat attagaacca ttaccatggg gatttctctt ttggactgta
    57301 tcgatccaga tatcaatcgt gctgcggaga aaatctatca aaaaattacg acaaaggcgg
    57361 ctaatttagt agctgttggt gatgaaattg cggctgagtt gggaattcct atcgttaata
    57421 agcgtgtatc ggtgacacct atttctctga ttggggcagc gacagatgcg acggactacg
    57481 tggttctggc aaaagcgctt gataaggctg cgaaagagat tggtgtggac tttattggtg
    57541 gtttttctgc cttagtacaa aaaggttatc aaaagggaga tgagattctc atcaattcca
    57601 ttcctcgcgc tttggctgag acggataagg tctgctcgtc agtcaatatc ggctcaacca
    57661 agtctggtat taatatgacg gctgtggcag atatgggacg aattatcaag gaaacagcaa
    57721 atctttcaga tatgggagtg gccaagttgg ttgtattcgc taatgctgtt gaggacaatc
    57781 catttatggc gggtgccttt catggtgttg gggaagcaga tgttatcatc aatgtcggag
    57841 tttctggtcc tggtgttgtg aaacgtgctt tggaaaaagt tcgtggacag agctttgatg
    57901 tagtagccga aacagttaag aaaactgcct ttaaaatcac tcgtatcggt caattggttg
    57961 gtcaaatggc cagtgagaga ctgggtgtgg agtttggtat tgtggacttg agtttggcac
    58021 caacccctgc ggttggagac tctgtggcac gtgtccttga ggaaatgggg ctagaaacag
    58081 ttggcacgca tggaacgacg gctgccttgg ccctcttgaa cgaccaagtt aaaaagggtg
    58141 gagtgatggc ctgcaaccaa gtcggtggtt tatctggtgc ctttatccct gtttctgagg
    58201 atgaaggaat gattgctgca gtgcaaaatg gctctcttaa tttagaaaaa ctagaagcta
    58261 tgacggctat ctgttctgtt ggattggata tgattgccat cccagaagat acgcctgctg
    58321 aaaccattgc ggctatgatt gcggatgaag cagcaatcgg tgttatcaac atgaaaacaa
    58381 cagctgttcg tatcattccc aaaggaaaag aaggcgatat gattgagttt ggtggtctat
    58441 taggaactgc acccgttatg agggttaatg gggcttcgtc tgtcgacttc atctctcgcg
    58501 gtggacaaat cccagcacca attcatagtt ttaaaaatta agaaaatagg agaaatttta
    58561 agttctattt aagattagat gtgtata
//
LOCUS       DAVMAH010000005        50714 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVMAH010000005 DAVMAH010000000
VERSION     DAVMAH010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50714
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.005"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(95..1114)
                     /gene="adhP"
                     /locus_tag="VYO94_000249"
     CDS             complement(95..1114)
                     /gene="adhP"
                     /locus_tag="VYO94_000249"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV1758952.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(1453..2265)
                     /locus_tag="VYO94_000250"
     CDS             complement(1453..2265)
                     /locus_tag="VYO94_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1758953.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            2455..3873
                     /locus_tag="VYO94_000251"
     CDS             2455..3873
                     /locus_tag="VYO94_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV1758954.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIYWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            3926..4633
                     /locus_tag="VYO94_000252"
     CDS             3926..4633
                     /locus_tag="VYO94_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1758955.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGISIVVLVLFIIGARKTQLASFNFSFFRTKDLARLGLSYLVIICSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGLVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            4728..5702
                     /gene="folP"
                     /locus_tag="VYO94_000253"
     CDS             4728..5702
                     /gene="folP"
                     /locus_tag="VYO94_000253"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV1758956.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            5704..7026
                     /locus_tag="VYO94_000254"
     CDS             5704..7026
                     /locus_tag="VYO94_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1758957.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALGDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            7007..7561
                     /gene="folE"
                     /locus_tag="VYO94_000255"
     CDS             7007..7561
                     /gene="folE"
                     /locus_tag="VYO94_000255"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV1758958.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            7604..8416
                     /gene="folK"
                     /locus_tag="VYO94_000256"
     CDS             7604..8416
                     /gene="folK"
                     /locus_tag="VYO94_000256"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV1758959.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(8461..8778)
                     /locus_tag="VYO94_000257"
     CDS             complement(8461..8778)
                     /locus_tag="VYO94_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV1758960.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            9135..9581
                     /gene="rplM"
                     /locus_tag="VYO94_000258"
     CDS             9135..9581
                     /gene="rplM"
                     /locus_tag="VYO94_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV1758961.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            9601..9993
                     /gene="rpsI"
                     /locus_tag="VYO94_000259"
     CDS             9601..9993
                     /gene="rpsI"
                     /locus_tag="VYO94_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV1758962.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(10255..10677)
                     /locus_tag="VYO94_000260"
     CDS             complement(10255..10677)
                     /locus_tag="VYO94_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1758963.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            10824..11000
                     /locus_tag="VYO94_000261"
     CDS             10824..11000
                     /locus_tag="VYO94_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758964.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            11401..13614
                     /locus_tag="VYO94_000262"
     CDS             11401..13614
                     /locus_tag="VYO94_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV1758965.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFATEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(13836..14312)
                     /locus_tag="VYO94_000263"
     CDS             complement(13836..14312)
                     /locus_tag="VYO94_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV1758966.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQR
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINTFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            14535..17738
                     /locus_tag="VYO94_000264"
     CDS             14535..17738
                     /locus_tag="VYO94_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV1758967.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNREKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            18118..18503
                     /gene="tnpA"
                     /locus_tag="VYO94_000265"
                     /pseudo
     CDS             18118..18503
                     /gene="tnpA"
                     /locus_tag="VYO94_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(18882..19511)
                     /locus_tag="VYO94_000266"
     CDS             complement(18882..19511)
                     /locus_tag="VYO94_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV1758968.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(19521..20522)
                     /locus_tag="VYO94_000267"
     CDS             complement(19521..20522)
                     /locus_tag="VYO94_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV1758969.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(20553..21194)
                     /locus_tag="VYO94_000268"
     CDS             complement(20553..21194)
                     /locus_tag="VYO94_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV1758970.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(21213..22028)
                     /locus_tag="VYO94_000269"
     CDS             complement(21213..22028)
                     /locus_tag="VYO94_000269"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV1758971.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            22299..22733
                     /locus_tag="VYO94_000270"
     CDS             22299..22733
                     /locus_tag="VYO94_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1758972.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            22745..23935
                     /locus_tag="VYO94_000271"
     CDS             22745..23935
                     /locus_tag="VYO94_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEV1758973.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            23946..24437
                     /locus_tag="VYO94_000272"
     CDS             23946..24437
                     /locus_tag="VYO94_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1758974.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            24452..25231
                     /locus_tag="VYO94_000273"
     CDS             24452..25231
                     /locus_tag="VYO94_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1758975.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            25218..26036
                     /locus_tag="VYO94_000274"
     CDS             25218..26036
                     /locus_tag="VYO94_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1758976.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            26036..26329
                     /locus_tag="VYO94_000275"
     CDS             26036..26329
                     /locus_tag="VYO94_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1758977.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            26351..28252
                     /locus_tag="VYO94_000276"
     CDS             26351..28252
                     /locus_tag="VYO94_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV1758978.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLIDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKGYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            28312..29313
                     /locus_tag="VYO94_000277"
     CDS             28312..29313
                     /locus_tag="VYO94_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1758979.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(29423..29758)
                     /locus_tag="VYO94_000278"
     CDS             complement(29423..29758)
                     /locus_tag="VYO94_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758980.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(29769..30011)
                     /locus_tag="VYO94_000279"
     CDS             complement(29769..30011)
                     /locus_tag="VYO94_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1758981.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(30027..30221)
                     /locus_tag="VYO94_000280"
     CDS             complement(30027..30221)
                     /locus_tag="VYO94_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1758982.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWKEDF"
     gene            30387..31337
                     /gene="rsmH"
                     /locus_tag="VYO94_000281"
     CDS             30387..31337
                     /gene="rsmH"
                     /locus_tag="VYO94_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV1758983.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMEMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            31349..31666
                     /gene="ftsL"
                     /locus_tag="VYO94_000282"
     CDS             31349..31666
                     /gene="ftsL"
                     /locus_tag="VYO94_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV1758984.1"
                     /translation="MAERMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            31670..33922
                     /locus_tag="VYO94_000283"
     CDS             31670..33922
                     /locus_tag="VYO94_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEV1758985.1"
                     /translation="MKWTKKVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGSKGNGITY
                     ANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQ
                     MNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTKDFVWRDILYQSNYE
                     PGSTMKVMTLAAAIDNNTFPGGEVFNSSELKVADATIRDWDVNEGLTGGGMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGIPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNNQSVRKSQKEIVGNPVSKDAA
                     SQTRTHMVLVGTDPRYGTMYNHSTGKATVNVPGQNVALKSGTAEIADEKNGGYLVGST
                     NNIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERAVAMKDSLNLQSTA
                     KTLDQVTNQSAYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKESSVEEGSNLAP
                     NQQVLLLSDKAEEVPDMYGWTKATAEAFSKWLNIELVFEGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            33924..34904
                     /locus_tag="VYO94_000284"
     CDS             33924..34904
                     /locus_tag="VYO94_000284"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV1758986.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIKFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLIASVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVVFYLFYERGGDMLSVFGYQVHLGIFYILFALFWLVGF
                     SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            35513..37618
                     /locus_tag="VYO94_000285"
     CDS             35513..37618
                     /locus_tag="VYO94_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1758987.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASINDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(37914..38396)
                     /locus_tag="VYO94_000286"
     CDS             complement(37914..38396)
                     /locus_tag="VYO94_000286"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV1758988.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(38491..39975)
                     /locus_tag="VYO94_000287"
     CDS             complement(38491..39975)
                     /locus_tag="VYO94_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV1758989.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            40128..41738
                     /locus_tag="VYO94_000288"
     CDS             40128..41738
                     /locus_tag="VYO94_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV1758990.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDFLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEEINVQEALANSDSIFYTYQKL
                     IQIRKENSWLIRADFKLLDTADKVFAYIRKDGDRRFLVVANLSNDKQNFSVDGKVRSV
                     LIENTAAKEVLEKQVLTPWDAFCVEMTD"
     gene            complement(41816..42650)
                     /locus_tag="VYO94_000289"
                     /pseudo
     CDS             complement(41816..42650)
                     /locus_tag="VYO94_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(42598..43983)
                     /locus_tag="VYO94_000290"
                     /pseudo
     CDS             complement(42598..43983)
                     /locus_tag="VYO94_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            44160..45605
                     /locus_tag="VYO94_000291"
     CDS             44160..45605
                     /locus_tag="VYO94_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1758991.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYFNLVVTALVLLVALVGLLLIIHKKAAKFTIFLLVLSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNIDLT
                     VNQSSSYLATYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDIHYYVRLNFTSFLKLIDLLGGVDVYNDQ
                     DFTSLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDHDRGRNQQKVIAAILQKLTSS
                     EALKNYSMIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGRGRTDLPSY
                     AMPDSNLYMMEINDSSLASVKTAIQDVLEGR"
     gene            45607..46338
                     /locus_tag="VYO94_000292"
     CDS             45607..46338
                     /locus_tag="VYO94_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV1758992.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLGKLEKNRIPTLNNS
                     RYALIEFSMNTPYRDIHSALIKILMLGITPVIAHIERYDALENNEKRVRELINMGCYT
                     QVNSSHVLKSKLFGEPYKFMKKRAQYFLERDLVHVIASDMHNVDSRPPHMAEAYDLVS
                     QKYGETKAQDLFIDNPRKIVMDQLI"
     gene            46347..47039
                     /locus_tag="VYO94_000293"
     CDS             46347..47039
                     /locus_tag="VYO94_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEV1758993.1"
                     /translation="MKEQNTIEIDVFQLLKTLWKHKLIILLVALVTGAGAFAYSIFIV
                     KPEYTSTTRIYVVNRNQENKPGLTNQDLQAGTYLVKDYHEIILSQDVLEKVATNLKLD
                     IPVKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSIREVAAEKIIAVTRVSDVT
                     TLEEARPATTPSSPNVRRNTLVGFLGAAAVTVITVLLIELFDTRVKRPEEVEDVLQMP
                     LLGVVPDFNKMK"
     gene            47049..47738
                     /locus_tag="VYO94_000294"
     CDS             47049..47738
                     /locus_tag="VYO94_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV1758994.1"
                     /translation="MPTLEISQAKLELAKKTEEYYNALCTNLQLSGDDLKVFSISSVK
                     AGEGKTTTSTNIAWAFAHAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPIALLQSKNFSTMLGTLRKYFDYIVVDTAPIGIVI
                     DAAIIIQKCDASILVTKAGETKRRELQKAKEQLEQTGKSCLGVVLNKFDTSVDKYGFY
                     GSYGSYRKQKK"
     gene            47753..49114
                     /locus_tag="VYO94_000295"
     CDS             47753..49114
                     /locus_tag="VYO94_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1758995.1"
                     /translation="MNEKLAKSSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYIL
                     HYFVFYISDYGRNFFKRRYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LLLHVFLVYMLNLFIKWYWKRAYPNFKGSKKVFLLTATSHVEKVLDRLIESDDVVGEL
                     VAVSVLDKPDFQHDDLKVVAEGEIVNFATREVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDWARNKQICEMAGLNVVTFSTTFYKTSHVIAKRVIDIIGSLVGLILCG
                     LVSIVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMCVDAEDKKRELMEQNTMQG
                     GMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQK
                     RRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVVYIDGWTIWKDIEILLKTVKVVLMKD
                     GAK"
     gene            49146..50324
                     /locus_tag="VYO94_000296"
     CDS             49146..50324
                     /locus_tag="VYO94_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV1758996.1"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNDAICYNIDVPNIGPARAIAYDIAAVNKAIEIAKKNKDEAPIF
                     YILACRIGPFIARLKKKIQAIGGTLFVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKYA
                     DLLVCDSKNIEKYIQNDYKQYQPKTTYIAYGTDTSPSILKSEDLKIRSWYQEKGLSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSKKDFVLITNVEQNKFYDQLLQETGFDKDPRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWRKDNLHKVIEESEQKTIEEIKEIDILSTEQVEKRFTWDFIVNEYENLFLLGK
                     "
BASE COUNT        15231 a         9094 c        11274 g        15115 t
ORIGIN      
        1 tgagtttttg aggagtaatc ttgaattctt atttaaaatt taatataaaa aagttggaag
       61 aagcttccaa cttttaaaat aggtttctat taaattagtg ggtgaagtcg agtaccatac
      121 gtccttggat ttggcctttt tccatttcgt cgaaaatggc aacagcatct tctactggac
      181 gtttttgaac aactgggact accagacctt ctgcaccaaa ttggaaggct tcttctaagt
      241 ctttacgagt tccgacaaga gaaccgatga cttggattcc atcgaggact gttttaacga
      301 tgctgagttc catcatttca gaaggaagac caacagcgac gacgcgacca ccagcacgaa
      361 tggagtcaac agcctggttg aaggcaactt tagacacagc agttacgaca gctgaatgag
      421 ctcctccatc agttttttct ttaatgagtc cagctacatc ttcaacttcg aggccgttaa
      481 tcacaatgtc agcgcctact tcttttgcaa gggtaagttt gtcattgttg atatcgactg
      541 cgataacatg agcattgaat acttttttag cgtattgaac agcgaggtta ccaagtccac
      601 cagcaccgta aagaacaacc cattggcctg gttcaacttt tgcttctttg atagctttat
      661 aggttgttac tccagcacat gtgatagaag aagcttgggc tggatcaagt ccgtcaggaa
      721 ctttgacagc atagtcagca gttacgatac attgttcagc cataccaccg tctactgagt
      781 agccagcatt tttcactgta cggcaaaggg tttcgcgacc agttgtacag tattcgcaag
      841 tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc accgacttta aggcttttca
      901 catctggagc aatctcttta acgataccga taccttcgtg cccaagaaca cgtcctggga
      961 cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg gcaaacgcca cagtattcaa
     1021 cttctacaag tgcttcccca gtttcaagtg gacggagtac tttttcttca atagcaacac
     1081 cagtgctttc tggatttaca acaacagctt tcatagctat cctccttgat attgaccgag
     1141 aacagggaca acgggactgg attgattttt tgtcaacaga gtcgagtgtg acgagctctc
     1201 ttgtatttat atgtgaagta tatcacaaaa gaaagccttt tccaaggttt tggagacaaa
     1261 aagtagaaca atcgattaac tggttgatga gactgtgaaa agagcacaaa gaccagcttg
     1321 caagctggtc atactcttcg aaaatctctt caaaccacgt cagcttcatc tacaacctca
     1381 aagcagtgct ttgagcaacc tacggctagc ttcctagttt gctctttgat tctcattgag
     1441 tatcagtgta ggctataaga ataagtcttg tagggttttg gcaaccccat cttggtcgtt
     1501 ggtaagggaa atttgctcat ctgcataagg gagtagctct ggattggcat ttttcatggc
     1561 ataacctttc ccagcaaaag cgagcatttc ggtatcattg tgttcatctc caaaggcaat
     1621 caaatctttt ttgtcacgat tcattatctt gagcaagtag tccaaagcaa aggccttgtt
     1681 gacacctttt ggggtacatt caaggatatt gagcggacct ccccaggtat tgatagaaag
     1741 ttgatgctgg tagaaggcgt tcatgtcttt tgccaaggca tatttgtcac tggctctggt
     1801 ctgcaagagg atacagttag ggtccttggt caccaattca ggctggaatt gatcttcagg
     1861 ctggaaagct tctacaccaa atagtttggg attggcaatc tcttcattgg gatttgtaat
     1921 gtagaatttt ttacgatatt ctccagcgat aaaatcggct tgaatgtcct ctgaacgttg
     1981 aaccatatct agcagatatt ttttgtctac agtcaaacac ttttcaaaat cccaaacttg
     2041 gtctggtaaa tgagtaaggg atccgttgaa gttaatcata ggagtgtcta agcccagttc
     2101 acggtaaaaa tcttttgaca tacggtaagg gcgacctgtc gtaataataa cctgatggcc
     2161 tttttcagca acttttttga tggttttttt ggtaaagtca gaaatttgac tgtctgagtt
     2221 gagcagggtt ccatccaggt caactgcaat aatttttttc gtcatatgga cctttctagt
     2281 gtgttttcag ataagatgtc ttctattata acagaaagca ggcagaaaag cagattccaa
     2341 acaaaaaatg aaattggatt aatttcttaa acaaatcaaa caaagacatt gaaaaagtga
     2401 atgataaatg atataattct attattgttc gtaaaaatta aaaggagatt gatgatggac
     2461 aaattattta aactaaaaga gaacggtaca gacgttcgta cagaggttct cgctggttta
     2521 acaactttct ttgcaatgag ctatattctc tttgtaaacc cacaaatact ttcacaaaca
     2581 ggaatgcctg ctcagggcgt cttcctagcg acgattattg gtgcagtagc gggtaccttg
     2641 atgatggctt tttatgctaa cttaccttat gcccaagcgc caggtatggg actcaatgcc
     2701 ttctttacct ttacagttgt attcgggctt ggttattctt ggcaagaagc cctagctatg
     2761 gtcttcatct gtgggattat ttcattgatt attaccttga caaatgttcg taaaatgatc
     2821 attgaatcga ttcccaatgc tcttcgctca gctatttcag ctggtatcgg tgtcttcctt
     2881 gcctatgtag ggattaagaa tgctggactt ttgaaattca cgattgatcc aggcaactat
     2941 actgttgtag gagaaggggc tgacaaagct caagcaacga ttgcagcaaa ctcttcagca
     3001 gttccaggat tggtcagctt taataatcca gctgttttag tggctcttgc aggacttgcc
     3061 attactatct tctttgtcat caaagggatt aaagggggaa ttattctctc tatcttgaca
     3121 acaactgttc ttgctattgc agttggtttg gttgatttgt ctagtatcga ttttgctaat
     3181 aaccatgttg gtgcagcttt tgaagatttg aagacaatct ttggtgcagc tcttggttca
     3241 gaaggtttgg gagctttggt ttcagataca gctcgcttgc ctgaaactct gatggccatt
     3301 cttgccttct cattgacaga tatttttgac acaattggta ccttgatcgg tacaggtgaa
     3361 aaagttggta ttgtagcgac aaatggtgaa aatcaccaat cagccaaatt ggataaggct
     3421 ctttactctg atttgattgg aacgacagtc ggtgccattg caggtacttc aaacgtaacg
     3481 acttatgttg agtctgctgc tggtatcggt gcaggtggac gtactggttt gacagccttg
     3541 gttgtagcta tctgttttgc gatttcaagc ttctttagcc cacttctagc gatcgtacca
     3601 acagcggcta cagctccaat cttgattatc gttgggatta tgatgcttgg tagcttgaaa
     3661 aatatctatt gggatgatat gtctgaagca gttcctgcct tcttcacatc tatctttatg
     3721 ggattcagct actctatcac tcaagggatt gcagttggtt tcttgactta cactttgact
     3781 aagcttgtca aaggtcaagt taaagatgtt catgccatga tttggatttt ggatgccttg
     3841 tttatcctta actacatcag catggcctta taatagaatg acccaggggg attttccccc
     3901 ttttttaata caaaggagat aggtgatgaa agagaaaaat atgtggaaag aattgttgaa
     3961 tcgtgcaggc tggattttgg tctttttact tgccgtcctt ttatatcagg ttcccctagt
     4021 ggttacctct attttgactt taaaagaagt agccctgcta cagtcagggc tgatagttac
     4081 tggtatttct attgtggttc tggtgctatt tattattgga gctcgtaaaa cgcaattggc
     4141 aagttttaat ttttcttttt ttagaactaa ggatttggca cgtttgggct tgagttattt
     4201 agtcattatc tgttcaaata tacttggttc tatcttgttg caactgtcaa atgagacgac
     4261 aacagctaac cagtctcaga ttaacgatat ggttcagaat agttctctga tttctagctt
     4321 cttcttgcta gccttgcttg ctccaatttg tgaggaaatc ttgtgccgtg ggcttgttcc
     4381 taaaaagatt ttccgaggca aggagaactt gggatttgta gtcggtacga ttgtgtttgc
     4441 tttattgcat caaccaagta atttaccttc tttattgatt tatggaggta tgtcgacagt
     4501 tctatcttgg acggcctaca agacccaacg tttggaaatg tcgatcttgc ttcacatgat
     4561 tgttaatggg attgctttct gtttgttggc tcttgtggtg attatgagtc ggacattagg
     4621 aatttctgtt taaaagtttt tatgtaggaa ccgacctctt tctactaggg aaagatgaat
     4681 gcaatcgtgt ccatcttttt ctttttatgg taaaatagaa aaataatatg atgaaaatcc
     4741 ttgagggagt gaccgatatg tcaagtaaag ccaatcatgc aaagacagtt atttgcggaa
     4801 ttatcaatgt aaccccagac tccttttcgg acggtggtca attttttgct cttgagcagg
     4861 cactccagca ggctcgtaaa ttgatagcag aaggagccag tatgctcgat atcggcggag
     4921 aatcgactcg gccgggaagt agctatgttg agatagaaga ggaaatccag cgtgttgttc
     4981 cagtgatcaa agcgattcgc aaggaaagtg atgtcctcat ctctattgat acttggaaga
     5041 gtcaagtagc agaggctgct ttggctgctg gtgccgatct agtcaatgat atcactggtc
     5101 tcatgggtga tgaaaaaatg gcccatgtgg ttgctaaagc tggagcgaaa gtggtcatca
     5161 tgtttaaccc agttatggct cgacctcagc atcctagttc gcttatcttc cctcattttg
     5221 gctttggtca aacctttaca gaaaaagagt tagctgactt tgaaacattg ccaatcgaag
     5281 acttgatggt ggctttcttt gaacgagcac tagcgagagc ggcagaagct ggtattgcac
     5341 cagaaaatat cctgttggat ccaggaattg gctttggtct gaccaagaaa gaaaatcttc
     5401 tccttttacg ggacctggat aaactacatc agaagggcta tccaatcttt ctcggagtgt
     5461 cgcgcaagcg atttgtcatc aatatccttg aagaaagtgg gtttgaagtc aatcctgaga
     5521 cagagcttgg tttccgaaat cgggacacgg cttcggctca tgtaactagt atcgctgcga
     5581 gacagggtgt agaagtggtg cgcgtgcatg acgtagctag tcacaggatg gcagttgaaa
     5641 ttgcctctgc cattcgtctg gctgatgaag cggaaaattt agatttaaaa caatataaat
     5701 aagatgaaag aaattgaaaa caatcagtgg attgctaact accggacgga tcaaccgcat
     5761 tttggcttgg aacgaatggt ggaactgtta gctttgcgtg gcaatcccca tcttaaactc
     5821 aaggttctcc atatcggagg gactaacggc aagggctcga ctattgcttt tttgaaaaag
     5881 atgctagaaa agctagggct gagagttggc gtgtttagtt cgccctatct cattcattac
     5941 acagaccaga ttagcatcaa tggggaatcg atctcagaag cgaggctaga agctctcatg
     6001 gcagactatc agtctttgct ggagggagaa gcggtcgcca atttacaggg cacaaccgag
     6061 tttgagatta tcacagccct agcctatgac tactttgcct cagagcaagt agatgtggct
     6121 atcatggaag ttggcatggg tggacttttg gatagtacca atgtctgtca gcccattttg
     6181 acaggaatta caactattgg cttggatcat gtggccctac ttggtgacac cttggaggcc
     6241 atagcagagc agaaggcagg tattatcaaa caagggatgc ccttggtaac agggcgtatt
     6301 gctccagaag ccttgactgt gattgaccgc attgcggaag ggaaagatgc gccgagactt
     6361 gcctacggga cagattatca ggttcgtcat caagaaagtg tggtgacagg ggaagtcttt
     6421 gactatacaa gtgctgtcag acaaggtcgc ttccagacta gcctgcttgg tttgtaccaa
     6481 atagagaatg ctgggatggc catagcttta cttgatactt tttgtcaaga agatggtcga
     6541 gagctagcaa gcaatgactt tcttggtcaa gccttggaag aaacaagttg gccagggcgt
     6601 ttggaaatcg tgtcaagaga tcccttgatg attttggatg gagcccataa tccccatgct
     6661 atcaaggcct tgttggtaac cttgcaagaa cgttttgcgg attatcataa ggaaatcctc
     6721 ttcacttgta tcaaaaccaa agccttgggg gatatgttgg acttgctggg agctatgcca
     6781 gataccgagc ttactctaac acattttgcg gatagtcggg cgacggatga aagcgtgctg
     6841 aaagaggcag ctaagtctag aaatctcagc taccaagatt ggcatgattt tctagagcag
     6901 aatttgacag ataaaaaaga agagaaacaa acagttagga ttgtcacagg ttccttgtat
     6961 ttcttgagcc aagtgagggc ctatctgatg gagaggaaga acgagaatgg atacacaaaa
     7021 gattgaagca gctgtaaaaa tgattatcga ggctgtagga gagaacgcta atcgcgaggg
     7081 cttgcaggaa acacctgctc gtgtagcccg tatgtatcaa gagatttttt caggtcttgg
     7141 tcaaacagca gaggaacatt tgtcaaaatc ctttgaaatt attgacgata atatggtggt
     7201 agaaaaggat atctttttcc ataccatgtg tgaacaccac ttcttgccat tttatggtag
     7261 agcgcacatt gcctacattc cagatggtcg tgtggcaggc ttgtctaagc tagcccgtac
     7321 ggttgaagtt tattcgaaaa aaccacaaat tcaagaacgt ttgaatatcg aagtggccga
     7381 tgccttgatg gactatctag gtgctaaagg agcctttgtt gtcattgagg cggaacatat
     7441 gtgtatgagt atgcgtggtg ttagaaaacc aggcactgca accttgacga cagtagctcg
     7501 tggtctattt gaaacagata aggacctccg cgaccaagct tatcgtttaa tggggctata
     7561 aaaagaatcc gtttcaagcg gatttttcta gaaaggaatc attatggatc aactgcagat
     7621 taaggatttg gaaatgtttg cctatcatgg tctttttcct agtgagaaag aattggggca
     7681 gaaatttgtc gtttcagcca tcctatccta tgatatgacc aaggcagcta cagacttgga
     7741 tttaacagcc tctgtccatt acggagaatt gtgtcagcag tggacgactt ggtttcagga
     7801 aacgagtgaa gatttgattg aaacggtagc ctataaactg gtggaacgta cctttgagtc
     7861 ttatcctctt gtccaagaaa tgaagttgga actgaaaaaa ccttgggcac cggtgcattt
     7921 gtcactagat acttgctcgg taaccattca tcgccgcaag caacgagcct ttatcgccct
     7981 aggaagcaat atgggagata aacaagcaaa cttgaagcaa gccattgaca aactgcgagc
     8041 tcgtggcatc tatattctca aagagtccag tgtcttagcg acggagcctt ggggtggagt
     8101 ggagcaggat agctttgcca atcaagtggt tgaggtggaa acctggctac cagcacaaga
     8161 cttgttagaa accttgttag ccattgagtc agagctggga cgggtgagag aagtgcattg
     8221 gggacctcgt ttgattgatt tggacttgct ctttgtggag gaccagatcc tttatacaga
     8281 cgacctcata ttgcctcatc cttacatagc ggaacgcctt tttgtccttg agtccttaca
     8341 ggaaattgcg cctcatttta tccatccgat attaaaacaa ccgatccgta acttgtatga
     8401 tgctttgaaa aaatagaaaa actctagttt tcagttactt gcaactgaag gctagagttt
     8461 ttaaaatagg tcattttctt ctgggaggag gatagtttct ctaccgtcca tgtctaaaac
     8521 cagtactctt gggggataac gagggtcgaa aggatggtta aagtcaaaat caatggctgt
     8581 agggaggtgt tgacttgaaa agtggaaggt aatctttcct tggttattaa gcaattgaaa
     8641 ctcgagttct tcttccaatt caaagacatt ttttaagaaa tggtcgataa tataccaaaa
     8701 agagtcaatg atgtcatcag gcaagctggt aacaatgcca aaactagcag accgcatgtg
     8761 ggtattggta aaagccatat ctctgtctcc tttcttttcc cttatcatac agcaaatagg
     8821 attaaaaatc aagaaaaggt gattttttga aaaggatttt aactacaggg aaaaagaagg
     8881 aaaaaaattc ccaaaaatct accgaagtta ataggtaaat tcccaaatta acttgattat
     8941 ataactttca gttactttga gaagttaccg aaaaatattt ttcatatcta ttgactttta
     9001 ggggtgaaat ttggtatgat agtaggcggt attgtttacc ccatttgaaa ggccccggaa
     9061 ccttccaaat acttttcgat gggaaggaac acccatcacc gtaaacaaaa atcgaactat
     9121 atataggaga aatcatgaac aaaacaacat ttatggctaa accaggccaa gttgaacgta
     9181 aatggtacgt agttgacgca actgatgtac cacttggacg tctttctgca gtagttgcta
     9241 gcgtacttcg cggaaaaaac aaaccaacat ttacaccaca cactgataca ggtgacttcg
     9301 tgattgttat caatgctgaa aaagttaaat tgactggtaa aaaagcaact gataaaatct
     9361 actacactca ctcaaaccac ccaggtggat tgaaacaaat ctctgcaggt gaacttcgtt
     9421 ctaaaaatgc agtacgtttg attgagaaat cagttaaagg tatgcttcca cacaatacac
     9481 ttggacgcgc tcaaggtatg aagttgaaag tatttgttgg agctgagcac actcatgctg
     9541 cacaacaacc agaagttctt gacatttcag gacttatcta aggaaaggaa caaataaagt
     9601 atgtcacaag cacaatatgc aggtactgga cgtcgtaaaa acgctgttgc acgcgttcgc
     9661 cttgttccag gaactggtaa aatcactgtt aacaaaaaag atgttgaaga gtacatccca
     9721 cacgctgacc ttcgtcttgt catcaaccaa ccattcgcag ttacttcaac tgtaggttca
     9781 tacgacgttt tcgttaacgt tgtaggtggt ggatacgctg gtcaatcagg agctatccgt
     9841 cacggtatcg ctcgtgccct tcttcaagta gacccagact tccgcgattc attgaaacgc
     9901 gcaggacttc ttacacgtga ctcacgtaaa gttgaacgta agaaaccagg tcttaagaaa
     9961 gctcgtaaag catcacaatt tagtaaacgt taattcgaaa gaattactat acttatacag
    10021 agcacctttc ggggtgttct ttttttatac tttcttacta aattggtgca attgacacag
    10081 ttgttgcgac tttagtcgct tacaaatgtg gctgcaacct gacaaggtca gttgcctcaa
    10141 aacgttaatc aatacaatta tatcaacgtt tcaaagcact caagagttta cctcatgggt
    10201 gcttttttta tgttttttga aaaagttcac ctcaaagttt accttatttt caccttattg
    10261 ttttagagac tgtaaggcaa attcaccgac ggccataggg actacattag aagtattgac
    10321 ataaatctgt gttgtacctg tgtcgctatg tattagagct tcagaaatgg cttctaagct
    10381 cattcctgct tgtttagcga gcgttgctcc ggtatgacgt agtttgtgtg gcgtagcgtg
    10441 tgtaagctct gggtgtcgtt ttctgatagt tttcatctta ttattgagat agtcagaatg
    10501 taaaggttta ttgatattgc ctttggtatc tatgtaagta aagatgaatt gttctggatt
    10561 actgatgata ccaaactttg ccagttcata tttttgttgt tttttccatg aagttagaag
    10621 ttgaagtaag tcattagaaa tagagaaaat gggaaatgtt tccacaataa aacgcatatt
    10681 atcagatggt taatgcgttt tatatttggg tttgaggctt ataaaatagg ataagcgtac
    10741 tgaaaactta gatatgacaa acaaaataaa atttttaaaa gctacagaga aacatggtat
    10801 aatgtatcta aaggaggtag catatgtcct tagatataga taaagaaaag atgacaatca
    10861 tgggaatagc ttttgaaaac cgatccgttt ttaagagtgt ttggtatgct ttaagtacaa
    10921 atatgattga aggatggcga cctacggtta gtgatgttga aaaattacga gatgaagctc
    10981 ttgctctggg gatgacttaa tgaagcgcaa ctgttatgag tcttatgact atgttgatcc
    11041 ggataattta tataccgatc cgggttcttc agttctaaga aataagcagg aaggaaaaaa
    11101 gcacgcgagc ttgaatatcg tatgattgct agtaagagtt tgaaattatt tatcaatcct
    11161 atcttagtta atagtttaaa agtagtttgt ttcacaactg cataagctta gaaaagttga
    11221 aaagtgataa ctctttaata aactcttggt ttgttaaaag atattttgtc cactacattt
    11281 tttcaattga ctattatttg tcatagatat aacagataga acattgcatt cagaataatg
    11341 aaaaacgcat caaaaatggt gcgttctgtt tttatgctac cataaaagga ggaaaacaaa
    11401 ttgaaaattt ttaagggaga gttttatcga atctctgtat taacagacaa gctagtaagg
    11461 ttagaatact ctcaaactgg aagttttgag gatagaacga cacaacttat ctataataga
    11521 gattttggcc aagtttcgtt agattatatc gagacatcaa acgtactaga tattatgacg
    11581 gactattttc atctgcactt taataaagga gaatttaacg ccgaaaattt atttatagaa
    11641 ttaaaaggaa attttgccgt atatggtagt cgctggtatt ttggtgaatc tattgaaacg
    11701 ttaaaaggaa cagctcggac tctggataag gcagatggag caatctcgtt agaagatgga
    11761 attattagcc gaaatggtat agccttattg gatgattctc aaggatttat ttgggatgaa
    11821 caatctggtt atattgagag agaaaatcaa attgacctgt atttctttgc ctatgggcat
    11881 gattatagag gagcaatcag agacttttac catttgactg gttcaacacc cttgttgcca
    11941 agatatgctt taggcaattg gtggagtaga tattggcctt atacgtcgga tgaatacttg
    12001 gatttaatag acagatttgc aacagagaaa attccattat ctatcggtgt gttagatatg
    12061 gattggcata taactgacat tccagctcgt tttggaagtg gctggacagg atatagttgg
    12121 aatagaaact taataccaaa tccagaacag ttattgcaac aacttcatga tagaaagtta
    12181 aaactctcct taaatgtcca tcctgctgat gggatacggg cttatgaaga agcttatcct
    12241 caaatcgcaa aacggttggg gttaaatgta gaactagaag aacctgctat ttttgatttt
    12301 tttaatccct cttttaggga agcctacttt aaagatgttc attatgagct agaaaagcag
    12361 ggagtagatt tttggtggat tgactggcaa caggggacac aaggcatgct agatccactt
    12421 tggcttttaa accattatca ctatcaggat agttgtaaaa atgcagaagg tggtttgatt
    12481 ttatcaagat atgcaggtcc tggtagtcac cgctaccctg ttggtttttc aggggatact
    12541 attatcagtt ggaattcctt aagatttcaa ccctatttta cagcgacagc atctaatatc
    12601 ggttatagtt ggtggagtca tgatatcggt ggacatatgt tgggggatta tgacgaagag
    12661 ctacaaacta gatggctaca gtttggtgtt tttagtccga ttactcgatt acatagttct
    12721 agaagtcctt ttaatagtaa agaaccttgg tttttttcag aaacaacatc taagattatg
    12781 aagaaatacc ttcgtttgag acatcagatg attccttatc tatataccat gaatgtaaag
    12841 acacatgagg aaggtgcccc attaatcagt ccaatctatt atttctatcc agagaatgat
    12901 gagagctata atgttccaaa ccaatacttt tttggaacag aactgatggt ggctcccatt
    12961 gtagaaaaga tggatttgac attccaatct gcaaaagtag atgtatggtt ccctgaaggt
    13021 gaatggtatg acttcttttc agagaaaaaa tacacaggtg gtgtgaagtt aagtgtttat
    13081 agggacatct cgactacgcc tgtgtttgca aaaagtggtg caatcattcc cttggttggt
    13141 tctgagatag gtatgggtgt tgatttacct gaggttgtag attggtatgt attcccaggg
    13201 aaacaacatt cttttgaaat gcttgaagat caaaatggtc aaagatataa aacaagatta
    13261 tcaatcgatt gggaaatggg aatggtagag ttagcattac aaggagattc tagtatcgtt
    13321 ccaagcaata gaaaacatag aattcatttt aaaggaacga atgtgtctat aattgaattg
    13381 ccaaataaga atgatacagc taaatttgaa tggaaagata ataaaaggac atctttaaat
    13441 gacgaagttt ttagactact aaagacagct tctcttccat atgaattaaa agatagattg
    13501 ttaaatcaat tcatcaatgc gaaaaactct catgacttaa tgaatatctt gcatcatcag
    13561 gataaggaat tgagagggcg tttgttggaa atgatattta ctagccaaaa ctaattgaaa
    13621 taattagaaa gtcatttgtt tagtgtatat gaagattctg tatggtattc gttatcactg
    13681 gtcacattga aaatgtgaaa taagcaccta caacatagac tttacaacac ttcatgtttc
    13741 atatcatggg gtgtttttct atttaagtca aagccaatca aaaaatctca ctattcatca
    13801 ggttaaagga aacctaatca tagtgagatt gtgaattata gtagagtttg tatcgcctct
    13861 tcaatttgtt ttgggtctgt ttttgaagaa aagcgttcaa agacttgccc atcacgacca
    13921 atgagaaact tagcgaaatt ccattcgatt cgttttccta gtgggccaga tttatggtct
    13981 tttaaccaga catagagagg gtctgcttcc ttaccgttga ccttaatctt ggcaaaacgt
    14041 gggaaggtgg tttgaaaatg taggctacag aaggtgttga tttcctctgc gctgccgggt
    14101 gcttgtccca taaactgatt gcaagggaaa tccaatattt cgaagccctg atcttgatag
    14161 cgttcataga gttcttgaag tctctggtac tggggcgtta aaccacatcc agtagcagtg
    14221 ttgacaatca agagaacttt gccacgatag ctatccaagg gagttgcttg gttgttttgg
    14281 ttcaaaacgg aaaaatcata aagtgaagtc atgagggcct cttttctttt tctacattgt
    14341 aacagttttt acttttttcg tcgagtcgga tggaagatat tgttgaagaa taagccctca
    14401 atatgataga aaccgtttac aaataacttt aaaaatggta tgatttaatt aaaccgattt
    14461 actttgttgc tataaatctc taatttgaga tttagttcct attgatttta caatatgttt
    14521 attggagtgt atacatgcaa acaaaaacaa agaagctcat tgtgagtttg tcttcacttg
    14581 ttttatcagg atttttatta aaccattata tgacagttgg agcggaagaa acgactacga
    14641 ataccattca gcaaagccag aaggaagttc agtatcagca aagggataca aaaaatttag
    14701 ttgaaaatgg tgattttggt cagacggagg acggaagcag tccgtggaca ggaagcaaag
    14761 ctcaggggtg gtcagcttgg gtagaccaga agaatagttc tgcagatgcc tcaactcgag
    14821 tcattgaggc taaggatggg gctatcacta tctcaagccc tgagaaatta agggcagcgg
    14881 ttcaccgtat ggttcctatt gaagctaaga aaaagtataa actgcgtttc aagattaaaa
    14941 cagatcataa agtcgggatt gccaaggttc gtatcattga ggaaagtggt aaggacaagc
    15001 gattgtggaa ttctgcaacg acgtcaggaa caaaggactg gcagaccatt gaagcagact
    15061 atagcccgac tttagatgtt gataaaatca agctggagtt attctatgaa acaggaactg
    15121 ggactgtttc ctttaaggat attgagctgg tagaggtagc agcccagctt tctgaggatt
    15181 ctcaaacaga taaacagctt gaggaaaaga ttgatttacc aattggaaaa aaacatgttt
    15241 tttctcttgc ggactatact tataaggtag aaaatcctga cgttgcttca gtcaaaaatg
    15301 gaattttaga acctcttaag gaagggacaa ccaatgtcat tgtcagtaaa gatggcaagg
    15361 aagtgaaaaa gattcctttg aagattctag cctctgttaa ggatgcatac acagcccgtt
    15421 tggatgactg gaatggcatc atcgctggga atcaatacta tgattctaaa aatgaacaga
    15481 tggccaaatt aaaccaggaa ttggaaggaa aggtagctga tagcctatct agtatttcaa
    15541 gtcaggcgga ccgcacctat ttgtgggaaa aattttcaaa ttataaaatg tctgcaaatc
    15601 tgactgccac ttatcggaaa ttggaggaga tggccaagca agtgaccaat ccttcttctc
    15661 gttattatca agatgaaact gtcgttcgaa cagtcaggga ttccatggaa tggatgcata
    15721 aacatgtcta caatcgtgaa aagagcattg ttgggaactg gtgggattat gaaatcggta
    15781 cacctcgtgc catcaacaat accttgtctc tgatgaaaga atacttctct gatgaggaaa
    15841 ttaaaaaata tacagatgtg attgaaaaat ttgtaccaga tcccgaacat ttccgaaaga
    15901 cgactgataa cccatttaag gctctaggtg gaaacttagt tgatatggga agagtaaaag
    15961 taatagctgg tttactgcgt aaggatgatc aagaaatttc ttctaccatt cgctcgattg
    16021 agcaagtgtt caagttggta gaccaaggtg aaggttttta tcaagatgga tcctatatcg
    16081 accacaccaa tgttgcctat acgggtgctt atgggaatgt tttgattgat ggcctgtctc
    16141 aactgttgcc agtcattcaa aagaccaaga atccaatcga taaagataaa atgcaaacca
    16201 tgtaccactg gattgataaa tcgtttgctc ctttgctggt gaatggagag ctgatggata
    16261 tgagtcgtgg acgctcgatc agtcgtgcaa atagcgaggg gcacgtggcc gcagtagaag
    16321 tactaagagg gattcaccga atagcggata tgtctgaagg agaaaccaaa caacgtttgc
    16381 agagtcttgt gaagaccatt gttcaatcgg atagttatta tgatgtcttt aagaatttga
    16441 agacttataa ggatatcagt ttgatgcaat ccttgttaag tgatgcagga gtcgcaagtg
    16501 ttccaagaac aagttaccta tctgccttta acaagatgga taaaacagcc atgtacaatg
    16561 cagagaaagg gtttggattt ggcttgtcac tcttttccag tcgtaccttg aattacgaac
    16621 acatgaacaa ggaaaataaa cgtggttggt atacgagtga tgggatgttc tatctttaca
    16681 atggcgattt gagtcactat agcgatggct actggccaac agttaatcca tataagatgc
    16741 ctggtacaac agagacggat gctaagagag cggatagcga tacaggtaaa gttttaccgt
    16801 ctgctttcgt tggaacgagc aaactagatg atgccaatgc gacagcaacc atggatttca
    16861 ccaactggaa tcaaacattg actgctcata agagctggtt tatgctaaag gataagattg
    16921 cctttttagg aagcaatatc caaaacactt caacagatac tgctgcaact acaatcgacc
    16981 agagaaaact ggaatcaagt aatccatata aagtctatgt caatgataaa gaagcctccc
    17041 ttacagaaca agaaaaggat tatcctgaaa cccaaagtgt ctttttagaa tcgtccgatt
    17101 cgaaaaagaa tattggttac tttttcttta agaagagttc aatcagcatg agtaaggctt
    17161 tgcaaaaggg agcctggaag gatatcaatg aaggacagtc agacaaggaa gttgaaaatg
    17221 aatttcttac gattagtcag gctcataagc aaaatggaga ttcttatggc tatatgctca
    17281 ttcctaacgt ggatcgtgcc accttcaatc aaatgataaa agagttagaa agtagcctca
    17341 tcgaaaataa cgaaaccctt cagtctgttt atgatgccaa acaaggagtt tggggcattg
    17401 tgaaatatga tgattctgtc tctactattt ccaaccaatt ccaagttttg aaacgtggag
    17461 tctataccat tcgaaaagaa ggggatgaat ataagattgc ctactataat cctgaaaccc
    17521 aggaatcagc tccagatcag gaagtcttta aaaagctaga gcaagcagct cagccacaag
    17581 tacagaattc aaaagaaaag gaaaaatctg aagaggaaaa gaaccattcg gatcaaaaga
    17641 atctccctca gacaggagaa ggtcagtcaa tcttggcaag tctagggttc ttgctacttg
    17701 gggcgtttta tctattccgt agaggaaaga acaactaatt tgttcatcat ctagatgaat
    17761 tacatgaaac tgtggaaaat agaaaaaatc cgaagaaggc caaatatctt cggatttttc
    17821 ttttaaaaaa ggataagttg atacttatcc tttttacttc attatgtgac tatagcgttt
    17881 tgaaactaga ataggacatc ataactgcta aaagatttct ataaattcat ttgattttcc
    17941 taatcaattt gttcgtatcc tatttcactc cactatatta gtccgtctcg ctccgtgagg
    18001 tgcgagacaa aacaaccacc cgctatacgg gtgcgcgtcg aaggttatac caaaaaaact
    18061 ccaaacgcga tacaataaag gtgttcaatc cacttgtaaa gcgaaaggag aaaaaatatg
    18121 gcacaaaagg ctcatagttt atctcacaca aagtggaggt gttctatcac attgtgttca
    18181 cccctaagta tagacgaaaa gtcatctata atcaatatag aagtagttta ggcgaaatat
    18241 ttcatcgctt gtgtagttat aaaggtgttg aaatgatcga gggtcactta atgccagacc
    18301 atgtacacat gttagtcagt attccgtcga ggctaagtgt ttcaagtttt atggggtatt
    18361 taaaaggcaa aagtgcactc atgatgtttg acaaacacgc caatctcaag tacaagtttg
    18421 ggaatcggca tttctgggcg gaaggttatt atgtaagtcc agtagggctt aatgaagcca
    18481 caattaagaa atatagtcaa gattaaagaa attatccagt ggatgatttc ttcacgagta
    18541 tgaaaatttg agaacgagta aagtatgata tatagtaaaa tgaaataaga acaggacaaa
    18601 atcgatcagg acagtcaaat cgatttttaa caatgtttta gaagtatagg tgtactattt
    18661 cagtttcaat ctactatagc actagataaa ttgagtgtaa aagaatatga ggatcccttt
    18721 agggatagtg gtaagtaata ccaaagtctc ttaaagaggc aagtgacgag tcaagagcaa
    18781 taaggcttga acaacgtgaa agccagcgtc tttaggcgct ggctgatgat ttgggcttat
    18841 agctctgaga taaaccaccc gttagacggg tagttatgat tttatctgag tgtaatatac
    18901 tgttgggcaa tctcgctgat gcggtcaaag ttgccttggg aagcgagttt attgagttcg
    18961 ccaccaattc caacggcatc tgcaccagca gcgaaccatt gagggatgtt gtttaggccg
    19021 actcctccgg ttaccattac ggaaacttgt gggatcggtg ccttgactgc agagatatat
    19081 gctggactga gagtactacc tgggaagagt ttgatgattt cactaccggc ttcaagtgca
    19141 gtcgtgatct ctgtgagggt aatacagcct ggaatgtacg gtgtgctgta gagattgcac
    19201 attttcgcag tttcagcatg gaaagatgga gaaacaacgt aatttgctcc agctagaatg
    19261 gcatctctag cagttacggc atcaagcaca gtacctgcac cgatacaaac actctgatcg
    19321 tcctgataca agtctacaag ttccttgatg atttgtcctg catactgatt ggtataggcg
    19381 atttcaatag ctttgatacc gcccttgata caagcaatcg aggcttgtag tccttcttcc
    19441 tttgtatttc ctcgaatgac agcgacaatt ttctgttttt ttagttcaat aatcgtatct
    19501 gatttggtca tgtaattctc ctaacgaatg atatcttgtg catttgccag taaattttca
    19561 atactagttg cggaagtgga gagatggtct cctggaagag tgcatttgag agttgcgctc
    19621 gcaactgcaa agtcaatggt agtttttagg gaggaatgat ggagtagttg gtaaagggca
    19681 ccagatataa aggcatcccc gctaccaatt cgttgataga ctgcagtttt tagttggaca
    19741 gactcttcaa atcgttcttc cagagcatag gcttgataga catttttgtc ttgctcatca
    19801 ctagatcgga gggtatggaa aatggccttg aaaccatagg cttcttttaa aagtcgcatg
    19861 cgattttcca cctcttctag gctagcactg tctcttggaa acatctctag attttggtca
    19921 tcaatcatga gaggatcaat accgaagcaa tagtcagtaa aacgtgcaaa cttagaaaat
    19981 tcatacttgg cttctaggac tgaaatcatc tttgttctca gattgagatc cattgaaacg
    20041 acaattcctc ggcgcttggc ttcttccaag agtaggagaa ggatcgcacg gacctcttga
    20101 ccgatagcta tggtgattcc actaaaatga aaatggctaa tcccctgaaa gagagaatcc
    20161 atatctagca tgtttggccg aatctggctg atactcgtat gcttacgatc gtagaaaact
    20221 tcactttgac gacaaccaaa gccgttctcc aaatagtaga ggccgattcg atcgccaagc
    20281 cgacagattg aactggtatc gatttggtgc tgtttcaaga atgtgagaaa acgatctcca
    20341 atctcgttgg cagggagtgc ggtaaagact ttcgttgaga tacccagggc ttgcaaatta
    20401 caagcgatgt taatttctga tccgccaaaa taagtcgaac tggcaacatg atcgccgata
    20461 ctggtggcat ctaatggtga gattcgaatt aatggttcgc caaacagtaa tattttcgtc
    20521 atccattagt tcctttctgg tttagaatag ctttacttgg ctaatacttc tttcaaataa
    20581 gcagcgactt catcatcttg gcagttttca aagaagtatt cttggaagta tttgccagag
    20641 atggtgtctt tgaggaagtc ttggtcgatt gttttaagga tggtcatcaa atcattgtgg
    20701 gtgatttgtt tcacctcgtt taagatacga gcgttgcgtt gttcagggat tacacgttct
    20761 cttgggtagc caccgcccat ttcttcagca aataagcgtt caaacatcaa tttgagggtc
    20821 agttctgccc cccagccaaa tcctttggca taagggatag acaaggcgtt accaccattg
    20881 atttgagaat aaaggtaagc gtcagttggg tccactgcta gaccacagac aacaccaggg
    20941 aagctgttta aagcaagcat agcccctaca cccgtaccac agccggtaac aacaaagtca
    21001 actgcctttg tatttaaaag gatggcagcc attagtccgt tctgcacata agttaattga
    21061 ctttctcctt cttctccacg cataccatag ttaaataatt ggtagccttt tttatctgtc
    21121 gcttctttta gactatcgta aataatgtga ttcttgctag cttgactatt ttcattgatt
    21181 aatgcgattt tcataagatc ttctttctat ttttactcag gttgttttcc gatgtaggct
    21241 aagataccgc catctacata taggatgtgg ccattgacaa aattgctggc atcactagcg
    21301 agaaagacag cagggcccat caaatcttca ggatttcccc aacgtgcagc aggtgttttt
    21361 gcaatgatga actggtcaaa tgggtggcga gaaccatctt cttgcaactc acgaagaggt
    21421 gctgtttgag gagtggcaat ataacccggt ccaattccgt tacattggat attggctcca
    21481 ccgtattcag acgcaatgtt gcgggtcaac attttcaagc cccctttagc agcagcataa
    21541 gcgctaactg tttcacgtcc cagttcgctc atcatcgaac aaatattgat aatctttcca
    21601 tgccctttct ttatcataga aggaataact gcctttgaaa cgataaatgg tgcgtttaag
    21661 tcaatatcga tgaccttacg gaaatcagcg gcgctcattt cgcacattgg aactcggcgg
    21721 ataataccag cgttattaac gaggatgtca atgacaccaa cctcttgttc gatttgcttg
    21781 accatggctt ggataccgtc ctcgtctgtc acgtcacaga catatccatg ggcttcgatg
    21841 ccaacttcac gataagcttc aatcccttta ttgaccagat cttgattgat atcgttaaag
    21901 acaatagtag cgccggcttc agcgtaggat ttggcaatag caaatccaat tccataagaa
    21961 gcgccggtga tgagagcaat ttttcctttt aaagaaaact gctcaattga gaatgatgta
    22021 tttgtcattt gatacttcct ttcaaatttg ttaagacttc tctataacca aattatattc
    22081 tagtaaaccg gttttgtcaa taaataaata tttttattta taaaaagatt tattttcctt
    22141 aaaaatgtaa tattttgaaa tttctgtcta ttaaaatgat taaaaagata atgaaagcgc
    22201 taatattttt ttaaaaaaac tattgacaag ataaaaataa aggattacaa tggggaatat
    22261 aaagtaaacc ggtaaaccta aacaagaaag gagaaaagat gaaaattgta cttgtagggc
    22321 atggacattt tgctacaggg atttatagtt ctttacaatt gattgcaggt aatcaagaaa
    22381 atgtggaggc gattgacttt gtggaaggaa tgtcagcaga tgaactcaag caaaaaatct
    22441 tacttgcaat ttcaaatgaa gaagaagttt taatcctaag tgatctcttg ggaggatcgc
    22501 cattcaaggt ttcttctacc ataatgggag aaaatccagc caaaacaatg aatgttctct
    22561 cgggtttgaa cttagccatg ttaatggaag cagtctttgc tagaatggct catagctttg
    22621 atgaggttgt taataaatca gtagtggcgg cccagggcgg agtcgtaaat ggtaaagaat
    22681 tgttttcaac ggatgcagag gaagaggaag aagatttcga atcgggtatt taaagggtaa
    22741 aagaatgata aaaaaggtta cgattgaaaa aataaaatcg cctgagcgct tcttagaagt
    22801 accacttctg acgaaagaag aagtcggcca ggcaatcgat aaggttattc ggcagttaga
    22861 actcaacctt gactatttca aggaagattt cccgacgcca gctacctttg ataatgtcta
    22921 tccaatcatg gataacacgg aatggaccaa tggtttctgg acaggagaac tgtggttggc
    22981 ttatgaatac agtcaacagg atgcatttaa aaacatcgct cataaaaatg ttctttcttt
    23041 cctggatcgt gtcaataaga gagtagaatt ggatcaccat gatctcggct tcttgtacac
    23101 accgtcttgt atggctgaat ataagataaa tggagatgga gaggctagag aagcaacctt
    23161 gaaagctgca gataagttga ttgaacgcta tcaagaaaaa ggtggtttta ttcaagcttg
    23221 gggagacttg ggcaagaaag agcattaccg tttgattatc gactgcttgc tcaatatcca
    23281 actcttattc tttgcttatc aagaaacagg cgatcaaaaa tactacgata ttgcagaaag
    23341 tcatttctat gcttcagcta ataatgtaat ccgtgatgac gcttcgtcct tccacacctt
    23401 ctattttgat cctgagacag gtcaaccctt taaaggtgta acgagacaag ggtatagtga
    23461 tgattcatgc tgggcacgtg gtcaatcatg gggagtctat ggtattcctt tgacttatcg
    23521 tcacttaaaa gacgagtcct gctttgactt gtttaagggt gtgaccaatt atttcttgaa
    23581 tcgtctgcca aaagatcatg tgtcctattg ggatttgatt tttaatgatg gtagtgatca
    23641 atcacgagat tcttcagcaa cagctatcgc cgtctgtggg attcatgaaa tgctaaaaca
    23701 tctcccagag gtggatgctg acaaagatat ttataaacat gctatgcatg ccatgcttcg
    23761 ttccttgatc gaacattatg caaatgatca atttacccct ggtgggacaa gtctcctcca
    23821 cggtgtgtac tcatggcatt caggtaaagg agtggatgaa ggcaatatct ggggtgacta
    23881 ctattaccta gaagccctta tccgtttcta caaagactgg aacctatatt ggtaggagga
    23941 gaaatatgac aatgccaaat attattatga cccgtatcga tgaacggttg attcatgggc
    24001 aaggacaact ttgggtaaaa tacctaggtt gtaatacggt cattgttgcc aatgacgaag
    24061 taagcacgga caagatgcaa caaactctga tgaaaacagt tgtgccagac tcagttgcca
    24121 tgcgtttctt ccctttgcaa aaggtgattg atatcattca caaggctaat cctgctcaaa
    24181 cgatctttat cgttgtaaag gatgtgaagg atgctttaac cttggtagaa ggtggtgtcc
    24241 ctatcaaaga aatcaatatt gggaacattc acaatgctac tggtaaagag caagtgacac
    24301 gctccatctt cctgggtgaa gaggacaagg cggccctcaa ggaattgagc caaactcatc
    24361 aagtaacatt taatacgaaa acaactccaa caggaaatga tggagctgtt caagtcaaca
    24421 ttatggacta tatttaaaag aggagatcgt tatgtcgatt aatgtatttc aagcgatttt
    24481 aattggatta tggacagctt tctgttttag tggaatgctg ttaggaattt acaccaatag
    24541 atgtattgtt ctgtcatttg gtgtcggaat tattctaggt gatctgccta ctgctcttgc
    24601 aatgggagct attggtgaat tggcttatat gggattcggt gttggtgctg gaggtactgt
    24661 tccaccaaac ccaatcggac ctggtatctt tggtaccttg atggctatca ctagtgctgg
    24721 taaagtcagt ccagaagcgg ctcttgccct ctctactccg attgctgtgg cgattcaatt
    24781 cttacaaact ttcgcctaca ctgtacgtgc tggtgcgcct gaaacagcga tgaagcactt
    24841 gaaaaaccat aatttgaaga aattcaagtt cactctaaat gcaacaattt ggttgtttgc
    24901 ctttattgga tttaccttgg gttgcttggg tgccctttca atggatacct tgttgaaact
    24961 cgtagactac attccaccgg tattgcttac aggtttgaca gttgctggta aaatgctccc
    25021 agctatcggt tttgcgatga tcttgtcagt gatggctaag aaagagttga ttccctttgt
    25081 cttgttggga tatgtttgtg cagcttatct aaacatccca acaattggta ttgcaattgt
    25141 aggtactatc tttgctttga ttgaatttta taacaagcca aaaacagcgg atcatgtggt
    25201 agaggaggaa gcacacgatg actggatcta acaaattaac aaaacgtgat tatcttaaaa
    25261 cgtctttgcg ggcattcttt tgtcaaaatg gatttaacta tagtaactat caagggttgg
    25321 gatatgccaa tgtgatgtat cctgctttga aaaaacacta tggagaggat caggaaggtt
    25381 tctaccaagc cttggaagaa aactgtgaat tctataatac caacccacac ttcctgcctt
    25441 ttattaccag cttgcatctt gtaatgttgg aaaatggccg tccggcaaaa gaaacacgta
    25501 gcatcaagat ggccttgatg ggaccattgg caggtattgg ggattctctt tctcaattct
    25561 gtttagctcc attgttctca accatcgcag cttcgtttgc tcaagaaggc ttggttgtcg
    25621 gtccaatctt gttcttcctt gcgatgaata cgattttaac agcgattaaa ttgtcaactg
    25681 gtctgtatgg atacaaacta ggaacaactg tgattgataa actaagcgaa cagatggcaa
    25741 cgatttctcg tattgccaat attatcggtg taaccgtaat tgctggtttg gcagcgacat
    25801 ctgttaagat tatggtgccg attacctttg ctgcagggga agttaaagca gacgctaaac
    25861 aaagtatcgt aagtattcag ggaatgcttg ataaggttgc tccagctctt ctaccagccc
    25921 tatttacact tttagtttac tacttgatca aagaaaagaa atggacaaca tataaactcg
    25981 ttattttaac agttatcatc ggaattatcg gaagctggct taagattata gcttaatgga
    26041 tacaacattg ttttatggaa tagtgattgt cttggcagtg agtccccttt tactgtcaag
    26101 ctttcattct attcgtcagc aaaagttgct tcgcaaacag atggagcaac gacaagagta
    26161 tttagcttct ttaacatctg gtgatgaagt gttgttattg tctggaattc atggaaaaat
    26221 catttctatc caagatgact tggtctcctt gcagattgca aaaggtgtgg tcatctatgt
    26281 agaaaaggaa agtgtaatgg gaaagacaaa agaactgctt tttaagtagt tctttttctg
    26341 gtaatagata atgaaagaag aaagaagaca attttttgaa agagtcgatg gaaaccaatg
    26401 tcgtgattat atcttgtccc actgttcaaa agactatgag aaagtcaaga gttcccttga
    26461 acgcttgata gacaatcgtt ttatgtttga tagtccttgg gatatggagc cttgttcaaa
    26521 aatccatcaa atccagccga tggtatggga tcaagtattt gaagatgatc cagaatggtc
    26581 ttatatgctc aatcgacaag aatatctctt gcagtttatg atagggtatc tggtagaagg
    26641 agataagggc tatatccaaa agtgcaagtt ctttctattt gattggattg agcaggtgag
    26701 agaattttct cctcaatcct tgatgactag aaccttggat acgggtattc gttcctttac
    26761 ttggttgaaa ctactcttgc tcctcttgaa atttgacttg ctagaggaga aagaactaga
    26821 gaaaattttg gtcagtctag aaaagcagat tgactttatg aaaagccact atcgcgccaa
    26881 gtacaccctt agtaactggg ggattttaca aacaattccg atgcttgcta tctattattt
    26941 cttttcagat aagatggacc tagaagaagc ttaccatttt gcttcagagg agttgaaaca
    27001 gcaaattgag acacagattt taggagatgg aagccagttt gaacagtcga ttctctatca
    27061 tgtagaggtt tataaagcct tgctggattt gtgtctcttg cttccagact tgcaagatag
    27121 ttaccgagag ttgctggaaa agatggcgac ctatattcaa atgatgacag gcttagatgg
    27181 acgaactttg gcttttggtg atagcgattc tacagaaacg acagaaattt tgagcctgtc
    27241 tgctgtggtt ttgaacaagg aagaccttct taacggtctg gatgttaaag tcgatttgct
    27301 tagcctcttg ttcctggggc gagaaaaggt caagcgactg caggaatttg aaaggagagc
    27361 ttggcagcct aagtccatga tctttgaaga ctctggacat gtctgcatta aggatgaaca
    27421 tcgttatcta tttttcaaaa atggtccgct aggaagtgcc catagccata gtgacgagaa
    27481 tagtttttgc ttacagtatc aaggccaacc tattttcata gatgctgggc gttattctta
    27541 tcgggagata tatgaacgtt atctcttaaa gagtgcttgg agtcattcga cctgcattgt
    27601 agatgggaaa gctccggaaa gaatcacggg atcctgggaa tatgaatact atcctcactc
    27661 cctgttttgt caccataaag aaagggaggg agtgcattat attgaggggg cttattggtc
    27721 agcagaacct gatttgcctt atcttcacaa gagaaaaatc ctcatgttgg tagaggatgt
    27781 ctggctcttg gtagatgaca tcaggtgtca aggtcagcat gaggcgttga ctcagtttat
    27841 ccttgacaag gatgtgacct atcaagatgg gaaaatcaat cagttgagac tatggagtga
    27901 agttgatttt gatttggaag ataccatcat ttctcctaaa tacaatgagc ttgaaagaag
    27961 tagcaaactc accaagcgcc aattctttga gaatcagatg ctggattata ccatcattgc
    28021 gcatgagagt tttgaaatta tccgtcattc tgtctaccag acagatgatc gtgaagtgga
    28081 aaatgctctg gcttttgaag tgaaaaatga cgaaacagac aagctgattc tgttattaag
    28141 cgaggatatt ggtgtaggtg aaaaattgtg cctcgttgac ggaacaaaaa tgcgtggaaa
    28201 atgtctagta tatgataaaa taaatgagag aatgattcgc ttgcagtgct agaaataggc
    28261 attttgaata gtgaatatgt tataataagt attagtagga ggtgttttag attggagaag
    28321 aaactgacca taaaagacat tgcggaaatg gctcagacct cgaaaacaac cgtgtcattt
    28381 tacctaaacg ggaaatatga aaaaatgtcc caagagacac gtgaaaagat tgaaaaagtt
    28441 attcatgaaa caaattacaa accgagcatt gttgcgcgta gcttaaactc caaacgaaca
    28501 aaattaatcg gtgttttgat cggtgatatt accaacagtt tctcaaacca aattgttaag
    28561 ggaattgagg atatcgccag ccagaatggc taccaggtaa tgataggaaa tagtaattac
    28621 agccaagaga gtgaggaccg gtatattgaa agcatgcttc tcttgggagt agacggcttt
    28681 attattcagc cgacctctaa tttccgaaaa tattctcgta tcatcgatga gaaaaagaag
    28741 aaaatggtct tttttgatag tcagctctat gaacaccgga ctagctgggt taaaaccaat
    28801 aactatgatg ccgtttatga catgacccag tcctgtatcg aaaaaggtta tgaacatttt
    28861 ctcttgatta cagcggatac gagtcgtttg agtactcgga ttgagcgggc aagtggtttt
    28921 gtggatgctt taacagatgc taatatgcgt cacgccagtc taaccattga agataagcat
    28981 acgaatttgg aacaaattaa ggaattttta caaaaagaaa tcgatcccga tgaaaaaact
    29041 ctggtattta tccctaactg ttgggcccta cctctagtct ttaccgttat caaagagttg
    29101 aattataact tgccacaagt tgggttgatt ggttttgaca atacggagtg gacttgcttt
    29161 tcttctccaa gtgtttcgac gctggttcag ccctcctttg aggaaggaca acaggctaca
    29221 aagattttga ttgatcagat tgaaggccgc aatcaagaag aaaggcaaca agtcttggat
    29281 tgtagtgtga attggaaaga gtcgactttc taaaatgaag gaaaatgact tgcaatttct
    29341 gttaagaaat aaaataatcc cacctagaac aagctaggtg ggattatttg cctatgaaat
    29401 gagaaattat gggagcaagc tcctaaatca actgtttttg atctacttct ttaactactt
    29461 gataaaagtt atagaagtag gccaaacttg aaatgatggt tacgactagg aatattgaaa
    29521 atttccattg gacagggttg gttaaaagtt gtggaaagga tatgaggaga aagaagaggg
    29581 ctgcgttgag gacaggtatc cgttttgatt gtattttctc aagtccttta ttgagcgcag
    29641 gaagaaagag gagtaggagt agtaaaactg tatgagaaac agctcctgaa ataagggcga
    29701 agaaaaggaa aatactgata aaaacatgaa tgatcagtag tctagctagt gatttcataa
    29761 ggcacctcct aatcctggtc ttttttagct cttgcaatac gaagtgagtc gacaatatgt
    29821 atcatcactc cgaaaaagaa agctcccagt atagttttaa aaatatgttt tgtatttaga
    29881 agagaactga taaaatttgg attttcactt gttagggtat caatgagtgg aattataaaa
    29941 aatatcactg ttccataaat cgaacctgct ttcagaccag gataacgtaa ctgtttcttt
    30001 tcttttttca tgagtttgct ccttttttaa aaatcttcct tccaaaagag actgttgagg
    30061 tcagtttgga ggctgcgagc gagattgaga cagagttcca gagttggatt gtacttgtcg
    30121 ttttcaatca tattgatggt ctgtctcgag acaccgatat ccttggcgag ctcgagctgg
    30181 gaaatgccca gttccttgcg aaattctttc acacgattca tctggtctcc tttctgattt
    30241 gtgtcgtata tatttgactt tattatagtc ttttaaacat aaagtgtcaa gtatttttga
    30301 catatttttt gaagaaatag tagtctcctt gtcctatttg tctgacaagt gcaagctggt
    30361 cggatttgtg gtaaaataga taagatatga caaaagaatt tcatcatgta acggtcttac
    30421 tccacgaaac gattgatatg cttgacgtaa aacctgacgg tatctacgtt gatgcgactt
    30481 tgggtggagc aggccatagc gagtatttat taagtaaatt aagtgaaaaa ggccatctct
    30541 atgcctttga ccaggatcag aatgccattg acaatgcgca aaaacgcttg gcaccttaca
    30601 ttgagaaggg aatggtgacc tttatcaagg acaacttccg tcatttacag gcacgtttgc
    30661 gcgaagctgg tgttcaggaa attgatggaa tttgttatga cttgggagtg tctagtcctc
    30721 aattagacca gcgtgagcgt ggtttttctt ataaaaagga tgcgccactg gacatgcgga
    30781 tgaatcagga tgctagtctg acagcctatg aagtggtgaa caattatgac tatcatgact
    30841 tggttcgtat tttcttcaag tatggagagg acaaattctc taaacagatt gcgcgtaaga
    30901 ttgagcaagc tcgagaagtc aaacctatcg agactacgac tgaattggca gaaattatca
    30961 agtcggccaa acctgccaag gaacttaaga agaagggtca tcctgccaag cagattttcc
    31021 aggctattcg aattgaagtc aatgatgaac tgggagcggc agatgagtcc atccagcagg
    31081 ctatggagat gttggctctg gatggtagaa tttcagtgat tacctttcat tccttggaag
    31141 accgcttgac caagcaattg ttcaaggaag cttcaacggt tgaagttccc aaaggtttgc
    31201 ctttcatccc agatgatctc aagcctaaga tggaattggt gtcccgtaag ccaatcttgc
    31261 caagtgcaga agaattagaa gccaataacc gctcgcactc agccaagttg cgcgtggcca
    31321 gaaaaattca caagtaagag gaaaaaagat ggcagaaaga atggaaaaaa caggtcaaat
    31381 actacagatg caacttaaac ggttttcgcg tgtggaaaaa gctttttact tttccattgc
    31441 tgtaaccact cttattgtag ccattagtat tatttttatg cagaccaagc tcttgcaagt
    31501 gcagaatgat ttgacaaaaa tcaatgcgca gatagaagaa aagaagaccg aattggacga
    31561 tgccaagcaa gaggtcaatg aactattacg tgcagaacgt ttgaaagaaa ttgccaattc
    31621 acacgatttg caattaaaca atgaaaatat tcgaatagcg gagtaagata tgaagtggac
    31681 aaaaaaagta atccgttatg cgaccaaaaa tcggaaatcg ccggctgaaa acagacgcag
    31741 agttggaaaa agtctgagtt tattatctgt ctttgttttt gccgtttttt tagtcaattt
    31801 tgcggtcatt attgggacgg gcactcgctt tggaacggat ttagcgaagg aagctaagaa
    31861 ggttcatcaa accacccgta cagttcctgc caaacgtggg actatttatg accgaaatgg
    31921 agtcccgatt gctgaggatg cgacatctta taatgtctat gcggtcattg atgagaacta
    31981 taagtcagca acgggtaaga ttctttacgt agaaaaaaca caatttaaca aggttgcaga
    32041 ggtctttcat aagtatctgg acatggaaga atcctatgta agagagcaac tctcgcaacc
    32101 taatctcaag caagtttcct ttggttcgaa gggcaatggg attacctatg ccaatatgat
    32161 ggctatcaaa aaagagttgg aaactgcaga ggtcaagggg attgatttta caaccagtcc
    32221 caatcgtagt tacccaaacg gacaatttgc ttctagtttt atcggactag ctcagctcca
    32281 tgaaaatgaa gatgggagca agagtttgct gggaacttct gggatggaga gttccttgaa
    32341 cagtattctt gcagggaaag acggtattat tacctatgaa aaagatcgtc tgggtaatat
    32401 tgtccccgga acggaacaag tttcccaaca aacggtagat ggcaaggatg tttatacaac
    32461 tatttccagc acccttcagt ccttcatgga gacccagatg aatgcctttc aagaaaaagt
    32521 aaaaggcaag tatatgacgg ctaccttggt cagtgctaaa acaggggaaa ttcttgcaac
    32581 aacgcaacgg ccgaccttcg atgctgatac taaggagggg ctgactaagg actttgtttg
    32641 gcgtgatatc ctctatcaaa gtaactatga accagggtca accatgaagg tcatgactct
    32701 cgctgctgct attgataata acactttccc aggaggagaa gttttcaata gtagtgagtt
    32761 aaaagtagca gatgctacta tccgagattg ggacgtcaat gaaggattaa ctggcggagg
    32821 aatgatgacc ttttctcaag gtttcgcgca ctcaagtaac gttgggatga cgcttcttga
    32881 gcaaaagatg ggagatgcta cctggcttga ttatctcaat cgctttaaat ttggtattcc
    32941 gactcgtttt ggcttgacgg atgaatatgc aggtcaactt ccagctgaca atattgtcaa
    33001 tatcgctcag agttcatttg gacaagggat ttcagtaact caaacacaaa tgattcgtgc
    33061 ctttacagcc attgccaatg atggcgtcat gttggagcct aaatttatta cggccttgta
    33121 tgacccaaat aaccaatctg ttcgtaaatc tcaaaaagaa attgtaggga atcctgtttc
    33181 taaggatgcg gcaagtcaaa ctcggactca tatggtctta gtaggaacgg atcctagata
    33241 tggaactatg tataatcata gtacaggaaa agcaactgtc aatgttccag gtcaaaatgt
    33301 agccctcaag tctggtacag ccgaaatcgc tgacgagaaa aatggaggct acttggttgg
    33361 ttctaccaac aacattttct cagttgtggc tatgaaccct gccgaaaatc ctgattttat
    33421 cttgtatgtg acggtccaac aacctgaaca ttattcaggt atccagttgg gagaatttgc
    33481 caatcctatc ttggaaagag cagtggccat gaaagattcc cttaacctcc aatctaccgc
    33541 taaaacgtta gatcaggtaa ccaatcaaag cgcttatgcc atgcctagca tcaaggatat
    33601 ttcacccggt gatttggcgg aagccttacg tcgcaatatt gtgcaaccaa tcgttgtagg
    33661 aacaggaaca aagattaaag aatcatctgt agaagaagga agcaatcttg ctcctaacca
    33721 gcaagttctt ctcttatctg ataaagcaga ggaagttcca gatatgtatg gttggacaaa
    33781 agcaaccgca gaagcttttt ctaagtggtt aaatatagaa cttgtatttg aaggttcggg
    33841 ctctactgtt cagaagcaag atgttcgtgc taatacagca atcaaggaca ttaaaaaaat
    33901 tacattaact ttaggagact aatatgttta tttccatcag tgctggaatt gtgacatttt
    33961 tactaacttt agtaggaatt ccggccttta tcaaatttta tagaaaggcg caaattacag
    34021 gccagcagat gcatgaggat gtcaaacagc atcaggcaaa agctgggact cctacaatgg
    34081 gaggtttggt tttcttaatt gcttctgttt tggttgcctt cttttttgcc ctatttagta
    34141 gccaattcag caataatgta ggaatgattt tgttcatctt ggtcctttat ggacttgtcg
    34201 gatttttaga tgactttctc aaggtctttc gtaaaatcaa tgaggggctg aatcctaagc
    34261 aaaaattggc tcttcagctt ttaggtgggg tcgttttcta ccttttctat gagcgtggtg
    34321 gcgatatgct ttcagtcttt ggttaccaag tgcatctagg gattttctat attctttttg
    34381 cccttttctg gctagtcggt ttttcaaatg cagtcaactt gacagacgga attgatggtc
    34441 tggctagtat ttctgttgtg attagtttgt ctgcctatgg agttattgcc tatgtgcaag
    34501 gtcagatgga tatccttcta gtgattcttg ccatgattgg tggtctgctt ggtttcttcg
    34561 tctttaacca taagcctgct aaggtcttta tgggtgatgt gggaagtttg gccctaggtg
    34621 ggatgctggc agctatctct atggctctcc accaagaatg gactctcttg attatcggaa
    34681 ttgtgtatgt ttttgaaaca acttctgtta tgatgcaagt cagttatttc aaactgacag
    34741 gtggtaaacg tattttccgt atgacgcctg tacatcacca ttttgagctt gggggattgt
    34801 ctggtaaagg aaatccttgg agcgagtgga aggttgactt cttcttttgg ggagtgggac
    34861 ttctagcaag tctcctgacc ctcgcaattt tatatttgat gtaagaatgg caccctgatg
    34921 tttcagggtg tttttgtgtt taaatacaca atgaaaatca aagaacaaac tagaaagcta
    34981 actttaggct gctcaaaata tagtagattg aaactagaat agtacacatc tacttctaaa
    35041 atattgttag aaatcgattt gactgtcctg attgatttgt cctgttctta tttcgtttta
    35101 atatacagtt ttgagatggt tgatagaact gacgaagtca gctcaaaaca cggttttgag
    35161 gttgtagata aggagaagct gatgtggttt gaagaggttt tcgaagagtg taaaaaaata
    35221 ttggtcagtc aaagtcaaaa ctcttgacct tttctgacca atgtagtata ttatgaacgt
    35281 aaggtaaatg aaagccttac tagaacactt atttaaagta aaatagaaag aggtgggtct
    35341 atgtttcatc tagaaatctt cagaagtaaa gatagtctac tcctgcttga aaaagaaaaa
    35401 ccagaaatag tacgtagggt agcgatctag ctagtctaaa ttttttaaaa caatggtcaa
    35461 agatagtcaa tatcagtaat cataactaag taaacaaaaa gaggtaaaga atatgaataa
    35521 caactttaat aattttaata acatggatga tttatttaac caattgatgg gtggtatgcg
    35581 aggatacagt tctgaaaatc gccgttactt aattaatgga cgcgaagtca cacctgagga
    35641 atttgctcac tatcgtgcga ctggtcaatt accaggaaat gcagaaactg atgtgcaaat
    35701 gccacaacag gcatcaggta tgaaacaaga cggtgtcctt gcaaaactag gtcgaaactt
    35761 aacagcagaa gcgcgtgagg gcaagttgga tcctgttatc ggacgaaaca aggaaattca
    35821 agaaacatct gaaatcctct cacgccgcac caagaacaat cctgttttgg tcggagatgc
    35881 aggtgttggt aagacagcag ttgtcgaagg tctagcgcaa gccattgtga acggagatgt
    35941 tcctgctgct atcaagaaca aggaaattat ttctattgat atctcaggtc ttgaggctgg
    36001 tactcaatac cgtggtagct ttgaagaaaa tgtccaaaac ttagtcaatg aagtgaaaga
    36061 agcagggaat attatcctct tctttgatga aattcaccaa attcttggtg ctggtagcac
    36121 tggtggagac agtggttcta aaggacttgc ggatattctc aagccagctc tctctcgtgg
    36181 agaattgaca gtgattgggg caacaactca agacgaatac cgtaacacca tcttgaagaa
    36241 tgctgctctt gctcgtcgtt tcaacgaagt gaaggtcaat gctccttcgg cagagaatac
    36301 ttttaaaatt cttcaaggaa ttcgtgacct ctatcaacaa caccacaatg tcatcttgcc
    36361 agacgaagtc ttgaaagcag cggtggatta ttctgttcaa tacattcctc aacgtagctt
    36421 gccagataag gctattgacc ttgtcgatgt aacggctgct cacttggcgg ctcaacatcc
    36481 agtaacagat gtgcatgctg ttgaacgaga aatcgaaacg gaaaaagaca agcaagaaaa
    36541 agcagttgaa gcagaagatt ttgaagcagc tctaaactat aaaacacgca ttgcagaatt
    36601 ggaaaagaaa atcgaaaacc acacagaaga tatgaaagtg actgcaagta tcaacgatgt
    36661 ggctgaatct gtggaacgaa tgacaggtat cccagtatcg caaatgggag cttcagatat
    36721 cgaacgtttg aaagatatgg cccatcgctt gcaagacaag gtgattggtc aagataaggc
    36781 cgtagaagct gtagctcgtg ctatccgtcg taaccgtgct ggttttgatg aaggaaatcg
    36841 cccaatcggc agcttcctct ttgtagggtc tactggggtt ggtaagacgg agcttgctaa
    36901 gcaattggca ctcgatatgt ttggaaccca ggatgcgatt atccgtttgg atatgtctga
    36961 atacagtgac cgtacagctg tttctaagct aattggtaca acagcaggct atgtgggtta
    37021 tgatgacaat agcaatacct taacagaacg tgttcgtcgc aatccatact ctatcattct
    37081 cttggatgaa attgaaaagg ctgatcctca agttattacc cttctcctcc aagttctaga
    37141 tgatggtcgt ttgacagatg gtcaaggaaa tacagtaaac ttcaagaaca ctgtcattat
    37201 tgcgacctca aatgctggat ttggctatga agccaacttg acagaagatg cggataaacc
    37261 agaattgatg gaccgtttga aacccttctt ccgtccagaa ttcctcaacc gctttaatgc
    37321 agtcatcgag ttctcgcact tgactaagga agacctttct aagattgtag atttgatgtt
    37381 ggctgaagtt aaccaaacct tggctaagaa agacattgac ttggtagtta gtcaagcggc
    37441 taaagattat atcacagaag aaggttacga cgaagtcatg ggggttcgtc ctctccgtcg
    37501 cgtggttgaa caagaaattc gtgataaggt gacagacttc cacttagatc atttagatgc
    37561 taaacatctg gaagcagata tggaagatgg cgttttggtt attcgtgaga aagcctaaga
    37621 tagaattttg aggataaaaa agaaggagcc agctgaaaaa aactggttcc tttttaggta
    37681 cgacaggcat gtcgtatagt agaagtgtat tattccagtt tcaatatact atagtagctc
    37741 agaagtcggt acttaaacgt gctatatcaa aaccagtcct tgaaaaacgt ggactggttt
    37801 cgtgtttgga ttattacctt gaacgacatg cgttaaaagt tagttgaacc gccgtatgcc
    37861 gaacggcacg tacggtggtg tgagaggggc tagagattat cccctactcg attttaaatc
    37921 acatgacgtt caaaggcatc atctgaaatc ccttgttcca agatgagttt tgcccattct
    37981 ttagcagaga agaggctgtg gtccttgtag tttccgcaag attcgatggt tgtccctggg
    38041 acatcttccc aagtagtagt ttcagcgatt tccttgagcg aatccttgat aacagctgca
    38101 attttagcac tggtgtgacg tccccacata atcatgtgga agcctgtgcg gcaaccaaat
    38161 ggcgaacagt caatcatgcc gtcaatgcgg gtacggatga gtttggctaa gaggtgctcg
    38221 atagtgtgaa ggccggcggt agggatggag tcttcgtttg gttgcaccaa gcgaatatca
    38281 taattggaga tgatgtctcc ttttggtcct gtttcttccc caatcaagcg aacatagggt
    38341 gctttgacaa tggtgtggtc aagttcaaaa ctttcgacaa taacttcttt tgacatggta
    38401 aatcctttca gttttcttct ctcattatat cataaaggtt gctcctgaga cagagagaaa
    38461 acctctccga ggctggagag gttgaaatct ttacttacga tataagcggt cgtattggta
    38521 gtatgggtca aaggttacgt tgatacccag tttacgaagg acattcttgt cttcatcagt
    38581 caagatgatg gttgagtggg cttcgcttcc tttgaggttg ccgagttctt ccatagcgcg
    38641 ggcagcatca ggattttctg tagctgtgat agcaagtgca atcaggattt catttgaatg
    38701 aaggcgtgga ttgcggctac cgagatgatc gattttaaga ccttggattg gcttaacaac
    38761 ttccggctcg attaatttta cttctttagc gatgtcagct gattttttga tggcgttgat
    38821 caaggcagcg gctgtaggcc caaagagttc tgagttctta ccagtgacga tttccccatt
    38881 tggcaattca aaggctaggg ctggtccacc agtttcttct gctttttggc gcgcaacgac
    38941 agcaacctta cggtctgcag gtgtgatacc gaggtcgttc atgagcaact caattttctt
    39001 gacggcagct tcgccaactt tttcagcttt gaagtcaaga actgtttgat agtaacggcg
    39061 gatgatttct tgtttagaag cttcgacagc agcctcgtca tctgtaatag cgaaaccaac
    39121 catgttgaca cccatatctg tcggtgaagc gtatggtgat tttccgagaa tacgttccaa
    39181 catgcgcttg agcactggga agatttcgat atcacggttg tagttgacag tggtttctcc
    39241 ataggtttga agatggaagg ggtcaatcat gttgacatca tcaaggtcag ctgtggcagc
    39301 ttcataagcc aagttaactg gatgatgaag gggaagattc caaacaggga aggtttcaaa
    39361 tttagcgtag ccagatttga tgccattgat ttggtcgtga tacatattgg acatacacgt
    39421 tgccaatttt ccagaaccag gtccaggagc ggttacgaca atcaagttgc gactggtttt
    39481 gatgtagtcg tttttgccca tgccttctgg ggaaatgatg tgatccatat ccgtcggata
    39541 tcctttgatt ggataatgaa gataagaatc aattccgttt ttctcaagtt ggttgcggaa
    39601 ggcatctgca gcgggttggc cagcgtattg tgtaatgaca acggaaccaa caaaaatccc
    39661 taattcattg aatttgtcaa tcaaacgaag aacttcttgg tcataagaaa tgcctaagtc
    39721 gccacgtgct ttggaatgtt caatgttgct agcattaatg gcaatcacaa cctcaacctg
    39781 ctctttcaat tcttgcaaga gcttgatttt gttgtcaggt tcataaccag gaaggacacg
    39841 agcagcgtgg aaatcttcta acattttacc gccaaactct aagtagagct tgccgtcaaa
    39901 ttggttaatg cgctccaaaa tatggtcgcg ttgtaaattc aaatattgtt cagaactaaa
    39961 agcttgtttt ttcatttttt tacctctgga ctctattata ataaaaaatt ggaagttagg
    40021 aaactacgga gctaaaaaag aaattaaaaa gattaagcaa acgcttgcac aaaattttaa
    40081 aaagtgctat catagactat agattatgaa aataatgagg taaacagatg caagaaaaat
    40141 ggtggcataa tgccgtagtc tatcaagtct atccaaagag ttttatggat agtaatggag
    40201 atggaattgg cgatttgcca ggaattacca gtaagttgga ctatctagcc aagctaggaa
    40261 tcacagcaat ttggctttct cccgtttatg acagccctat ggatgataat ggctacgata
    40321 ttgctgatta tcaagcgatt gcaacgattt ttggaaccat ggaggatatg gatcaactga
    40381 ttgcagaagc taagaagcgt gatatccgta tcatcatgga cttggtggtc aatcatacct
    40441 cggatgagca tgcctggttt gtagaggcct gtgaaaatcc taatagccct gagcgagact
    40501 actatatctg gcgcgatgaa cccaatgacc tagattctat ctttagtggg tctgcttggg
    40561 aatacgatga aaagtcaggt caatactatc tccacttttt cagcaagaaa cagccggatc
    40621 tcaactggga aaatgaaaaa cttcgccaga aaatttatga gatgatgaac ttctggattg
    40681 ataaaggtat tggtggtttc cgtatggatg ttattgacat gattggcaaa attcctgacg
    40741 agaaggtagt caataatggt cctatgctcc atccctatct caaggaaatg aatcaggcga
    40801 cctttggaga taaggatttc ttgacagtag gggagacttg gggagcaacg ccagagattg
    40861 ccaagctcta ctctgatcca aaggggcaag aattgtctat ggtcttccag tttgaacata
    40921 tcggtcttca gtatcaggaa ggtcagccta aatggcacta tcaaaaagag ctgaatatcg
    40981 ctaagttaaa agaaatcttc aacaaatggc agacagagtt aggagttgag gacggctgga
    41041 attccctctt ctggaacaac catgacctcc ctcgtattgt ctcaatctgg ggaaatgacc
    41101 aagaataccg cgaaaaatct gccaaagcct ttgcaatctt acttcatctc atgagaggaa
    41161 ctccttatat ctaccaaggt gaggagattg ggatgaccaa ctatccgttt gaaacactgg
    41221 atcaagtaga agatattgaa tctctcaact atgcgcgtga ggctcttgaa aaaggtgttc
    41281 cgattgaaga aatcatggac agtatccgtg ttattggacg agacaatgcc cgtaccccta
    41341 tgcaatggga cgagagcaaa aacgctggtt tctcaacagg tcaaccttgg ttggcggtta
    41401 atccaaacta cgaagaaatc aacgttcaag aagcactggc aaactcagat tctattttct
    41461 atacctatca gaaactcatc cagattcgta aggaaaacag ctggttgatt cgagctgatt
    41521 ttaaattact cgatacggct gataaggtct ttgcttatat ccgtaaggac ggtgaccgtc
    41581 gcttcctagt cgtggctaat ttatccaatg ataaacaaaa cttttcagta gatggaaaag
    41641 ttagatctgt cttgattgaa aacactgcgg ctaaagaagt acttgaaaaa caggtcttga
    41701 ctccatggga tgctttctgt gtggaaatga ctgactagaa tgagcaagag cctgggacaa
    41761 aatagttctc gaccacaaaa aagctagaga tttccaattg tggaactcta gctttttaat
    41821 tttgagtcat tctcttattg tattttagga ggttattggc cataagtacc aatcccatgt
    41881 caattctcac ttgacgcttg cccctcagat tacatctctt gtaacccaaa caagccttta
    41941 tctgcccaaa gacaggttcc acatcaatct tgcgttgagc gaaaatctgt ctaccttggg
    42001 gagataaaag cgcctgacat tctttagctt tcaagttttg atagccttcg ttcatataca
    42061 gtcccctttt gaggggctga ttcaggttcg tcgacgtagt aaaccttgat ttcttgttga
    42121 aagtctgtct gtgttttctg atgtttggta tggtgaaaac gataatacta gccatcagga
    42181 tgtgtatagc tatcctcctt gtcattatag tgccaattcg ctaagtttct agctgactgt
    42241 ttatagcctc tcttctgttc cttatcaaac atggcatatt taatcagatg gtttacctcc
    42301 ttttcatcta aacgaaggag gttctcttca cttccatatc cagcatctgc gacaactgtc
    42361 ttcaagtcat gcggataggt ttcaaggaat ggcagaagag tcttggtatc tgtcggattt
    42421 gaaaagacat catagtgaag aacaaattgg ttttccgtag cgatttgaag attataagca
    42481 gccttgggtt gactattttt catatgttct tccttcatcc gcataaaagt ggcatctgga
    42541 tcggttttgg aaaaactgtt aggcccttga aatgtctcct gatagttctc atatttttca
    42601 gcacgtactg aaaaatcctc ctttaaactc ttcataatcc tttttatttt tatgaagata
    42661 ttgtttgaaa gatgtgagtt tccacggatg ggtttgtgga gggatatact tgcgtctttc
    42721 tttttttgtt ctggttcttg ttcaaggttt ttcgaataga gttcatgatt tagtagctcc
    42781 tttgtgtgat agattttgtc agcgatattg aggtagatgt caccatcaaa tgcttttata
    42841 actaatgctt ttgtctttct gatgaaatag acttcttttc cttgctcggt agggatatag
    42901 caacgatttt ggaatcggat atggtgtcca ctatcgacga ctctctcccg ccagtttagc
    42961 tagaatgaga tttcgttcag agggcttagg agcctcctca aagacagaga gttttgtctt
    43021 gtttccaaac tgttcattaa aggtttggat ataggaaggc agaaaggtat tggcttcttc
    43081 caaggtatga atcttgtttc gttccagttc gataggcagg agagattgta gtatctgatt
    43141 gagtctttcg actctccctt tagcttgagg gatagaggtt gtctcaagga gaattcccag
    43201 ttggtgacag gcgtatccaa attgtgtatg ggtgtcgtcc tccattttct tagagttgga
    43261 ggcttgatag gtaaaaacag ttctcttatc tgttttgatt tgaacaggaa tgccgtggtt
    43321 ggctaagatt tgttcgagga catgatagta agcattcaag gtctcttgtt tgtcaaaata
    43381 agcgcctagg atattgccag aagcatcatc aatggctagg tgtaagttag aggtttctgc
    43441 tccaaaccag gcatgagggc tggcatccat ttggatgagt tctccagcaa atttctttct
    43501 gggtctacta ggatgtacct ttttagggtc ttccaggaag ttttcagccg tcggtaagat
    43561 tggattgtct aggggttgct tggggttcag tttagcttgc tttcttactc tcttctttgt
    43621 ctttctatgg gacttaggcg acaggatatt tttcttatag agtatttttc taacagttgt
    43681 atcagagagc tgaattcctt cttcttcagc tagcaattca cagaaatgac ggacatttgg
    43741 tttatatgtt tcataggaga ggtatttctt taggatacgt tctttgattt catcagggat
    43801 tgcatgtttt ggttttcgat ttctgtttcc gtgtctgaag gcttcttttc ctttctgttg
    43861 ataggctagt agcagacgat tgatttgcct ttcagaaaga ttgagctcga cacaggctcg
    43921 tttctttgtt ttctttcctt gggctatagc ttttatcaca agatattttt tcgtttcatt
    43981 catattcagt tggatccttt acatatgact attctaccaa atgggacatt tttacgttcg
    44041 atttactaaa gacattatca cattcgaatt acacaagatg cagatagtga aaaaaaggtg
    44101 tagacattac cgtaaaaaag tgatataatt gtaagatgtt caatgtatag gtgttaatca
    44161 tgagtagacg ttttaaaaaa tcaggttcac agaaagtgaa gcgaagtgtt aatatagttt
    44221 tgttgactat ttatttattg ttagtttgtt ttttattgtt cttaatcttt aagtacaata
    44281 tccttgcttt tagatatttt aatctagtgg taactgcgtt agtcctacta gttgccttgg
    44341 tagggctact cttgattatc cataaaaaag ctgcaaagtt tactattttt ctgttggtgc
    44401 tctctattct tgtcagctct gtgtcgctct ttgcagtaca gcagtttgtg ggactgacca
    44461 atcgtttaaa tgcgacttct aattactcag aatattcgat cagtgtcgct gttttagcag
    44521 atagtgagat tgagaatgtt acgcaactga cgagtgtgac agcaccgact gggactgata
    44581 atgaaaacat tcaaaaacta ctagctgata tcaaatcaag tcagaatatc gatttgacgg
    44641 tcaatcaaag ttcgtcttac ttggcaactt acaagagttt gattgcagga gagactaagg
    44701 ccattgtctt aaatagtgtc tttgaaaata tcatcgaatc ggagtatcca gattacgcat
    44761 cgaagataaa aaagatttat accaagggat tcactaaaaa agtagaagct cctaagacgt
    44821 ctaagaatca gtctttcaat atctatgtta gtggaattga tacttatggt ccgattagtt
    44881 cggtgtcgcg ttcagatgtc aatatcctga tgactgtcaa tcgagatacc aagaaaattc
    44941 tcttgaccac aacgccacgt gatgcttatg taccaatcgc agatggtggg aataatcaaa
    45001 aagataaatt gacccatgcg ggcatctatg gagttgattc gtccattcac accttagaaa
    45061 atctctatgg agtggatatc cattactatg tccgtttgaa cttcacttct ttcttgaaat
    45121 tgatcgattt gttgggtggg gtagatgttt ataatgacca agatttcaca tctctacacg
    45181 ggaagttcca tttcccagtt ggaaatgtcc acttagattc tgagcaggct ctgggatttg
    45241 ttcgtgagcg ctattcccta gcggatggtg atcatgaccg cgggcgcaat caacaaaagg
    45301 tgattgcggc tatccttcaa aaattaactt cgagcgaagc gctgaaaaat tatagtatga
    45361 tcattgatag cttgcaagat tctatccaaa caaacatgcc ccttgagacc atgataaact
    45421 tggtcaatgc tcagttagaa agtggtggaa cgtacaaagt aaattcgcaa gacttgaagg
    45481 gtaggggacg gacggatctt ccttcctatg cgatgccaga tagtaacctc tatatgatgg
    45541 aaattaacga cagtagcctt gcatctgtca aaactgctat tcaggatgtg ttggagggca
    45601 gatgaaatga ttgatattca ttcgcacatt gtctttgatg tagatgatgg tcccaagtca
    45661 agagaggaaa gtaaggctct cttgacagaa gcctacaggc agggggtgcg aaccattgtc
    45721 tctacctctc accgtcgcaa gggcatgttt gaaactccag aagagaagat agcagaaaac
    45781 tttcttcagg ttcgggaaat agctaaggaa gtcgcgagtg acttggtcat tgcttatggg
    45841 gccgaaattt actacacacc agatgttttg ggtaagctgg aaaaaaatcg gattccgacc
    45901 ctcaataata gtcgttatgc cttgatagag tttagtatga acacccctta tcgcgatatt
    45961 catagtgcct tgattaaaat attgatgttg ggaattactc cagtcattgc ccacatcgag
    46021 cgctatgatg ctcttgaaaa taatgaaaaa cgcgttcgag agctgattaa tatgggctgt
    46081 tacacgcaag taaatagttc acatgtcctc aaatccaaac tttttggaga accttataaa
    46141 ttcatgaaaa aaagagctca gtatttcttg gagcgtgatt tggttcatgt gattgcaagt
    46201 gatatgcata atgtggacag cagacctccc catatggcag aagcatatga ccttgtttcc
    46261 caaaaatacg gagaaacgaa ggctcaggac ctttttatag acaatcctcg aaaaattgta
    46321 atggatcaac taatttagga gaaataatga aagaacaaaa cacgatagaa atcgatgtat
    46381 ttcaattact taaaaccttg tggaaacaca agctaatcat tttattagtg gcacttgtga
    46441 caggggcggg agcttttgca tatagcattt ttattgttaa gccagaatat acaagcacca
    46501 cgcgtattta cgtagtcaat cgtaatcaag aaaataagcc gggactgacg aatcaggact
    46561 tgcaggcagg aacttatctg gtaaaagact accacgaaat tatcctttcg caagatgtat
    46621 tggaaaaggt agcgacaaat ttgaaattgg atattccagt aaaaacgtta actagcaaag
    46681 tgcaagtgac tgtaccagcc gacactcgta tcgtctcaat ctctgtcaag gataaacaac
    46741 cagaggaagc cagtcgcatt gctaattcta tacgagaagt tgctgcagaa aagatcatcg
    46801 ctgtaacgcg agtatctgat gtaacgacgc ttgaagaagc gcgaccagct acgactccct
    46861 cttctccaaa tgttcgacgc aacaccttag ttggttttct tggagccgcc gccgtaacag
    46921 taattactgt tcttttgatt gagttgttcg atacccgtgt aaaacgtcct gaagaagttg
    46981 aagatgtact gcaaatgcca cttctaggag tcgttccaga ttttaataaa atgaaatagg
    47041 aggaagttat gccaacgtta gaaatctcac aggcgaaatt agaacttgcg aaaaagacag
    47101 aggaatatta taatgctttg tgcacgaacc tacagttaag tggagatgat ttgaaagtat
    47161 tttctatcag ttctgtgaaa gcaggagaag gaaaaacaac gacttccacc aatatcgctt
    47221 gggcttttgc gcatgcaggt tacaaaacgc tgctgattga tgcagacatg cgtaactccg
    47281 ttatgtcagg tgtctttaaa tcaagggaaa ggattactgg gctaacagaa tttctatcag
    47341 ggacaacaga cctgtcacag gggctttgcg ataccaatgt tgagaatctc tttgtgattc
    47401 aggctggctc tgtgtcacca aatccgatag cccttcttca aagtaagaat ttcagtacaa
    47461 tgcttggaac cttgcgtaaa tattttgact atatcgtcgt agacactgct cctatcggta
    47521 tcgtgattga tgcggctatc attatacaga aatgtgatgc ttctatttta gtgacgaagg
    47581 caggtgaaac aaaacgacgg gaacttcaaa aagcgaaaga acagttggaa caaactggga
    47641 agtcgtgttt aggagttgtg ttgaataaat tcgatacttc agtagacaaa tacggttttt
    47701 atgggagtta tgggagttac aggaaacaga aaaaataggt tgagggatag agatgaatga
    47761 aaaactagca aagtcttcag tagctatagt ccagagtttt cttgttattt tattgactta
    47821 tctacttagc gctgtgagag aaacagagat tgtttcaaca acagctattg tactttatat
    47881 cctccactat tttgtctttt atatcagtga ttatggacgg aatttcttta aaaggagata
    47941 tttgattgaa cttgtccaga cattgaaata tatcctattc tttgcgctag cgattagtat
    48001 ttctaatttt ttcttagagg atcgatttag tatttccaga cgaggcatga tttacttcct
    48061 cctattacat gttttcttag tctatatgct aaacctattt atcaagtggt attggaagcg
    48121 ggcttatccc aactttaaag gaagtaagaa ggttttccta cttacagcaa cttctcatgt
    48181 cgaaaaggta ctggatagac taatagaatc agatgatgtt gttggggagt tggtagccgt
    48241 cagtgtttta gataaaccag attttcagca tgatgattta aaggttgtag cagaggggga
    48301 gatcgtaaac tttgcgactc gtgaggtggt cgatgaagtc tttatcaatc ttccaagtga
    48361 aaaatacaat attggagagc ttgtctctca gtttgaaacg atgggaattg atgtaacagt
    48421 caatctaaat gctttcgatt gggcacgtaa caagcaaatt tgtgagatgg caggactaaa
    48481 tgttgtgact ttttctacaa cattttataa gactagccat gtgattgcta agcgggttat
    48541 tgatattatc ggttccctgg taggtttgat actatgtggt ctagtcagta ttgtgctggt
    48601 tcctttgatt cgaaaggatg ggggctctgc tatttttgct cagacgcgta taggaaaaaa
    48661 tggccgccat ttcacttttt acaagtttcg ctctatgtgt gtagatgctg aggataaaaa
    48721 gagagaactc atggaacaaa ataccatgca gggtggaatg tttaaggtgg acgatgatcc
    48781 tcgtatcacg aaaattggtc attttatacg gaagacgagc ttggacgagc taccacagtt
    48841 ttataatgtt ctaaagggag atatgagttt ggtaggtaca cgaccaccaa cagtggacga
    48901 gtatgaacac tataccccag aacaaaaacg tcggctaagt tttaaacctg gtataacagg
    48961 cttatggcag gtcagtggac gaagtgaaat caaaaatttc gatgaagttg tcaaattaga
    49021 tgtggtctat attgatggtt ggacaatctg gaaagatatt gaaattttat tgaagacagt
    49081 taaagttgta ttgatgaagg atggagcgaa atagtttgct tttgtttcag actattagga
    49141 gaaaaatgaa gaagtcagtt tatatcattg gttcaaaagg gattcccgct aagtatgggg
    49201 gctttgaaac ctttgttgag aaattaacag aatatcaaaa agatggtaac atccaatact
    49261 atgttgcctg catgcgcgaa aattctgcaa aatcaggatt tacagcagat acatttgagt
    49321 acaatgatgc tatttgttac aacattgatg tgcctaatat tggtcctgct agagccattg
    49381 cttatgatat tgctgctgtg aataaagcga ttgaaatagc taagaaaaac aaagatgaag
    49441 ctcctatttt ttacattcta gcttgtcgta tcgggccttt tatagctaga cttaagaaaa
    49501 agattcaagc tatcggaggt actctgtttg tcaatccaga tggacatgag tggcttcggg
    49561 ctaaatggag cctgccggtt cgaaagtatt ggaaattttc ggaacagttg atggtcaaat
    49621 atgcagattt attggtctgt gatagcaaaa atattgaaaa atatatccag aatgactata
    49681 agcaatatca accaaagacg acttatattg cttacgggac ggatacaagt ccgtctatcc
    49741 tgaaatccga agatctaaaa attcgtagtt ggtatcagga aaaaggactt agcgaaaatg
    49801 gctattatct agtggtggga cgattcgtcc ctgaaaacaa ctacgaaacc atgattcgtg
    49861 aatttatcaa atctaagtcc aagaaggact ttgtcctcat cacaaatgtg gagcagaata
    49921 aattttacga ccagttgtta caggagactg gttttgacaa agatcctagg gttaaatttg
    49981 taggtactgt ctatgaccaa gaattgctta agtacattcg tgaaaatgct tttgcctatt
    50041 tccatgggca tgaggttgga gggaccaacc cttctctact agaagctcta gcatccacaa
    50101 aactgaatct gttgctagat gttggtttta accgtgaggt tggtgaagac ggggctattt
    50161 attggagaaa agataatctt cataaggtta ttgaagagag tgaacaaaaa acaatagaag
    50221 aaataaaaga aatagatatt ctatctacag agcaggtaga aaaaagattt acttgggatt
    50281 ttattgttaa tgaatatgaa aatttatttt tactagggaa ataattatct aagttacaag
    50341 gattttattt gaggaagctt tgatggaagt tcatcacttt cttagacaat tatctaaata
    50401 acttatgtta ttcatgaagt ttttaaaatg atagatattc tccctttttg caaagatact
    50461 aaaattatag agaggaaata tgcccagtag ttgatagtgt ttttgggtag ggttaaacga
    50521 catagtttta agacaaactg gtggagattt aagaaataag tagttcttat taaatcaaaa
    50581 acgtgttctt attctatatt gtcatttagt caaaggtatc aagtatgact attaaaatta
    50641 attatatgtt ttttgtttgt ctctcttttt tcggtatagt tttaagtagt tcacaggtaa
    50701 tagtgaatct gggt
//
LOCUS       DAVMAH010000006        50427 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVMAH010000006 DAVMAH010000000
VERSION     DAVMAH010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50427
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.006"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(17..175)
                     /locus_tag="VYO94_000297"
     CDS             complement(17..175)
                     /locus_tag="VYO94_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV1758997.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(247..393)
                     /locus_tag="VYO94_000298"
     CDS             complement(247..393)
                     /locus_tag="VYO94_000298"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1758998.1"
                     /translation="MEYSLKYEETFKTILKDGHLVLSNNLAERAIKSLVMGRSKRVQW
                     TLLA"
     gene            complement(389..685)
                     /locus_tag="VYO94_000299"
     CDS             complement(389..685)
                     /locus_tag="VYO94_000299"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1758999.1"
                     /translation="MVNCEPLEAYRQLEEAELVGCWAHVRRKFFEATPKQADKSSLGA
                     KGLAYRDQLFALERDWEALPADERLQKRPTPNGRLLCLVPASVSFSRFKTRKGN"
     gene            complement(758..1070)
                     /locus_tag="VYO94_000300"
                     /pseudo
     CDS             complement(758..1070)
                     /locus_tag="VYO94_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523994.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1089..1475)
                     /locus_tag="VYO94_000301"
     CDS             complement(1089..1475)
                     /locus_tag="VYO94_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HEV1759000.1"
                     /translation="MTYPVEREEITYKRKKAKGKRQAILAQFDSEEVHHRLENCICPD
                     CQGELKEIGASLQRQELVFILAQLKRVNHIQHAYKCQTCSKNNPSDKIVKAPIPKAPL
                     AHSLGSASIIAHTIHQKFILKVPNYR"
     gene            complement(1459..1653)
                     /locus_tag="VYO94_000302"
     CDS             complement(1459..1653)
                     /locus_tag="VYO94_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1759001.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLSLFEEEQNMEEDSDLPS"
     gene            complement(1823..2173)
                     /gene="tnpB"
                     /locus_tag="VYO94_000303"
                     /pseudo
     CDS             complement(1823..2173)
                     /gene="tnpB"
                     /locus_tag="VYO94_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(2154..2339)
                     /locus_tag="VYO94_000304"
     CDS             complement(2154..2339)
                     /locus_tag="VYO94_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759002.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2643..4205)
                     /gene="guaA"
                     /locus_tag="VYO94_000305"
     CDS             complement(2643..4205)
                     /gene="guaA"
                     /locus_tag="VYO94_000305"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV1759003.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAVEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRKTVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4347..5045
                     /locus_tag="VYO94_000306"
     CDS             4347..5045
                     /locus_tag="VYO94_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1759004.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQISYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(5088..5984)
                     /locus_tag="VYO94_000307"
     CDS             complement(5088..5984)
                     /locus_tag="VYO94_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1759005.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5993..6928)
                     /locus_tag="VYO94_000308"
     CDS             complement(5993..6928)
                     /locus_tag="VYO94_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV1759006.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSAPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6925..7650)
                     /locus_tag="VYO94_000309"
     CDS             complement(6925..7650)
                     /locus_tag="VYO94_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proteinase"
                     /protein_id="HEV1759007.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNEIFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7734..8369)
                     /locus_tag="VYO94_000310"
     CDS             complement(7734..8369)
                     /locus_tag="VYO94_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV1759008.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEKYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(8371..9198)
                     /locus_tag="VYO94_000311"
     CDS             complement(8371..9198)
                     /locus_tag="VYO94_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1759009.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9220..10146)
                     /locus_tag="VYO94_000312"
                     /pseudo
     CDS             complement(9220..10146)
                     /locus_tag="VYO94_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809127.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10797..11408
                     /locus_tag="VYO94_000313"
     CDS             10797..11408
                     /locus_tag="VYO94_000313"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1759010.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11453..12181
                     /gene="rlmB"
                     /locus_tag="VYO94_000314"
     CDS             11453..12181
                     /gene="rlmB"
                     /locus_tag="VYO94_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV1759011.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(12220..13131)
                     /gene="trxB"
                     /locus_tag="VYO94_000315"
     CDS             complement(12220..13131)
                     /gene="trxB"
                     /locus_tag="VYO94_000315"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV1759012.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQERAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13197..13421)
                     /locus_tag="VYO94_000316"
     CDS             complement(13197..13421)
                     /locus_tag="VYO94_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV1759013.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13499..14242)
                     /locus_tag="VYO94_000317"
     CDS             complement(13499..14242)
                     /locus_tag="VYO94_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1759014.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(14242..15042)
                     /locus_tag="VYO94_000318"
     CDS             complement(14242..15042)
                     /locus_tag="VYO94_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1759015.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15200..15556)
                     /locus_tag="VYO94_000319"
     CDS             complement(15200..15556)
                     /locus_tag="VYO94_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1759016.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15569..16081)
                     /locus_tag="VYO94_000320"
     CDS             complement(15569..16081)
                     /locus_tag="VYO94_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV1759017.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGEPQDLSNLLLAPIGTNFEKRVWSYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(16081..16575)
                     /locus_tag="VYO94_000321"
     CDS             complement(16081..16575)
                     /locus_tag="VYO94_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1759018.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16710..17156
                     /locus_tag="VYO94_000322"
     CDS             16710..17156
                     /locus_tag="VYO94_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV1759019.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            17153..17800
                     /locus_tag="VYO94_000323"
     CDS             17153..17800
                     /locus_tag="VYO94_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV1759020.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLVIIPAII
                     NQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(17821..18402)
                     /gene="pdxT"
                     /locus_tag="VYO94_000324"
     CDS             complement(17821..18402)
                     /gene="pdxT"
                     /locus_tag="VYO94_000324"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV1759021.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18403..19278)
                     /gene="pdxS"
                     /locus_tag="VYO94_000325"
     CDS             complement(18403..19278)
                     /gene="pdxS"
                     /locus_tag="VYO94_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV1759022.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19430..20809)
                     /locus_tag="VYO94_000326"
     CDS             complement(19430..20809)
                     /locus_tag="VYO94_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1759023.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            21103..22026
                     /locus_tag="VYO94_000327"
     CDS             21103..22026
                     /locus_tag="VYO94_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV1759024.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            22086..22691
                     /locus_tag="VYO94_000328"
     CDS             22086..22691
                     /locus_tag="VYO94_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1759025.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEETDGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22710..23954
                     /locus_tag="VYO94_000329"
     CDS             22710..23954
                     /locus_tag="VYO94_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1759026.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLEICLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(24177..24434)
                     /locus_tag="VYO94_000330"
     CDS             complement(24177..24434)
                     /locus_tag="VYO94_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV1759027.1"
                     /translation="MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24476..26512)
                     /locus_tag="VYO94_000331"
     CDS             complement(24476..26512)
                     /locus_tag="VYO94_000331"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV1759028.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEEEFDLDFLDIKGGRVSRGHRFLGQETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKTIEAERGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAEHLENVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26772..27689)
                     /gene="glyQ"
                     /locus_tag="VYO94_000332"
     CDS             complement(26772..27689)
                     /gene="glyQ"
                     /locus_tag="VYO94_000332"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV1759029.1"
                     /translation="MSKKLTFQEIILTLQRFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(27881..28642)
                     /locus_tag="VYO94_000333"
     CDS             complement(27881..28642)
                     /locus_tag="VYO94_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1759030.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMTPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVFDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(28915..29757)
                     /locus_tag="VYO94_000334"
     CDS             complement(28915..29757)
                     /locus_tag="VYO94_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV1759031.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29871..31262)
                     /locus_tag="VYO94_000335"
     CDS             complement(29871..31262)
                     /locus_tag="VYO94_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV1759032.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31497..31874)
                     /locus_tag="VYO94_000336"
     CDS             complement(31497..31874)
                     /locus_tag="VYO94_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1759033.1"
                     /translation="MLCQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGTQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLASHSFIVK"
     gene            31999..32976
                     /locus_tag="VYO94_000337"
     CDS             31999..32976
                     /locus_tag="VYO94_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1759034.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            32973..34055
                     /locus_tag="VYO94_000338"
     CDS             32973..34055
                     /locus_tag="VYO94_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1759035.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(34119..35140)
                     /locus_tag="VYO94_000339"
                     /pseudo
     CDS             complement(34119..35140)
                     /locus_tag="VYO94_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(35524..36720)
                     /gene="tuf"
                     /locus_tag="VYO94_000340"
     CDS             complement(35524..36720)
                     /gene="tuf"
                     /locus_tag="VYO94_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1759036.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(37653..38522)
                     /locus_tag="VYO94_000341"
     CDS             complement(37653..38522)
                     /locus_tag="VYO94_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1759037.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(38745..39265)
                     /locus_tag="VYO94_000342"
                     /pseudo
     CDS             complement(38745..39265)
                     /locus_tag="VYO94_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(39223..40329)
                     /locus_tag="VYO94_000343"
     CDS             complement(39223..40329)
                     /locus_tag="VYO94_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV1759038.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSYRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(40440..40694)
                     /locus_tag="VYO94_000344"
     CDS             complement(40440..40694)
                     /locus_tag="VYO94_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759039.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(41052..41585)
                     /locus_tag="VYO94_000345"
     CDS             complement(41052..41585)
                     /locus_tag="VYO94_000345"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1759040.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(41572..41787)
                     /locus_tag="VYO94_000346"
     CDS             complement(41572..41787)
                     /locus_tag="VYO94_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1759041.1"
                     /translation="MGKERREQEHIERKKRVVKNRKIPLEELKTFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(41754..41897)
                     /locus_tag="VYO94_000347"
     CDS             complement(41754..41897)
                     /locus_tag="VYO94_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV1759042.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KNT"
     gene            42131..43849
                     /locus_tag="VYO94_000348"
     CDS             42131..43849
                     /locus_tag="VYO94_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV1759043.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            43960..44307
                     /locus_tag="VYO94_000349"
     CDS             43960..44307
                     /locus_tag="VYO94_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1759044.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(44586..45422)
                     /locus_tag="VYO94_000350"
     CDS             complement(44586..45422)
                     /locus_tag="VYO94_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1759045.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(45435..46064)
                     /locus_tag="VYO94_000351"
     CDS             complement(45435..46064)
                     /locus_tag="VYO94_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1759046.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(46074..46715)
                     /locus_tag="VYO94_000352"
     CDS             complement(46074..46715)
                     /locus_tag="VYO94_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1759047.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(46861..48090)
                     /locus_tag="VYO94_000353"
     CDS             complement(46861..48090)
                     /locus_tag="VYO94_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV1759048.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(48080..49246)
                     /locus_tag="VYO94_000354"
     CDS             complement(48080..49246)
                     /locus_tag="VYO94_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1759049.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFIAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            49390..50403
                     /locus_tag="VYO94_000355"
     CDS             49390..50403
                     /locus_tag="VYO94_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV1759050.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
BASE COUNT        14982 a        11102 c         9065 g        15278 t
ORIGIN      
        1 ctaatctgga gatttcttat ttgcactttt cttgtacaac tttagtccac ggtaaatagg
       61 cctctaaaac ctctttgttt acgagagttt cctcgtttgg aagacattct agaagatagg
      121 atagatattt ctcactattt agttgatgac gtttagctgt ttccaataag ctcataataa
      181 tagctcttgc tttagctcct tcaaaaactt tgagaaaaca accaccctcg cttttttaaa
      241 ctgagcttag gctaaaagag tccactggac tcttttactc cgtcccataa ccaatgattt
      301 aatggcgcgt tcagctagat tattggaaag gaccagatgt ccgtctttta aaatggtctt
      361 aaaggtttct tcatacttga ggctgtattc aattgccctt cctagttttg aacctgctaa
      421 aactgactga cgccggcact aagcaaagaa gtcttccatt aggggttgga cgtttctgta
      481 gtcgttcatc agctggcaaa gcctcccagt ctctttccaa ggcaaataac tggtcacgat
      541 aggctaaacc tttagctcct aaggatgatt tatctgcttg cttgggggtc gcttcaaaaa
      601 atttccttct cacatgcgcc caacatccaa caagttcagc ttcttccagt tgacgataag
      661 cttctagcgg ttcgcagttt accaagctta gcgtcgcctt gctcctaaac cttagactgc
      721 tatcgcatag gcagaactag aggactaaag ttctaagtta ctgccgcaac atatcacaat
      781 gcatatagcc agaataattt cctaggaatt cttgcactac cgaaccactc cgacgctgat
      841 catggtggta cagcgtaatc ccttgtttct cagctttccc agacaaaaaa gtccaatagt
      901 aagtcagctg actatcactt tctaagaccc gataagaggt ttcatctgca tgaagaagag
      961 cttgttctaa caacttttct cgtaaaaggt tataaaggga ctctaaatag tattgactcg
     1021 ccttgataat gccaattagc aatttcctta cgtgtgattg gtaaacccat cttagcccaa
     1081 tcttcttctt agcgataatt gggtaccttc agaataaact tctgatggat ggtgtgagcg
     1141 ataatagaag ctgagccaag gctatgcgcc aaaggggctt taggaatagg agctttcacg
     1201 attttatcac ttggattatt cttactgcat gtttggcatt tgtaagcgtg ttggatatga
     1261 ttcactcttt ttaattgcgc aagaataaag accaattctt gtcgttgaag gctcgctcca
     1321 atctctttta gctctccctg acagtcaggg caaatgcagt tctctaagcg atgatgaact
     1381 tcttctgaat caaattgggc aagaatagct tgacgtttcc ctttagcttt cttacgttta
     1441 taggtgattt cttctctttc aactgggtaa gtcagagtct tcttccatat tttgttcctc
     1501 ttcaaaaaga ctgagttgtc cagatgggca aacacttttc tcagaggatt ttccatagag
     1561 cttttgcgtt agataagcca cttgttcacg aagaagggca agttcattgg tgagactatc
     1621 aattgtagca ctctgttgtt gaatgatttt caatcttctc ccatagactt tcctccttat
     1681 ttcctaactt tattatatag tgtattgaat ctataacagt acaccttgac tgctaaaata
     1741 tttctataaa ttaatttgac tttcctgata gagatgttca tatcttattt caattcacta
     1801 tactaaaaag aaagtcctca tttcaataga aatcacgact ttctgatgaa tttatttttg
     1861 gagtgataga aaagcccttc ataagccagt ctacttgttc agatgtgaga gctttgacat
     1921 ccttttctgt actgggtcaa gtcagtctgc cgttctcaaa gcgtttatat agtagccaaa
     1981 atccttgacc atcccagtaa agggctttaa agcggtcttt acgtccacca caaaagagaa
     2041 aaacttgacc ggagaaagga tctaattcaa agtgggtttt aaccagataa gccagtgaat
     2101 caatgccttg cctcatatcc gttttcccac atacgagata gacctgccct aggctagata
     2161 gatgaattgt catagagcaa caccttatcc aaaagctgtt ctaccatttc gagattgaga
     2221 gattgaaaaa aacttacttc aagcttgcca atacgaattt taagcagaat atcatttctc
     2281 tttttagaat caaaaggacg agattgtgga atctctacag gaacaatagg ttgtggcatt
     2341 aaaatatcct ccaatagttt tactttacta atagtataca ggaggagctc catgaatgat
     2401 agataccttg ttatgacgcg cttaccatat tagaaagttg gctctctaat taaattaatt
     2461 ctcattatat atatcaaaag accgcagttt gaaaactacg gtctaatttt ttgtccaaat
     2521 gtaaaccact tggaactatt attcaattta ttctttttag caaatgttcc cgttttaatc
     2581 ccagttacag tttttaatcc tctgtaaccg ttgattttac aaagctttta atttttttgc
     2641 gattattccc actcaactgt tgcaggtggt ttacttgtaa tatcgtagac gatacggtta
     2701 acatgatcca cttcatttac gatacgtact gagatttttt gaagtacttc ccatggaatt
     2761 ttggcaaaat cagcagtcat accatcgata gaagtgatag cacggattgc aatcgtgtag
     2821 tcatacgtac gaccgtcacc cataacaccg actgaacgaa cgcctgtgtt aacagtgaag
     2881 tattgccaaa tatcgcggtc aagtccagct ttagcgattt cttcacgaag aatagcgtct
     2941 gattcacgaa cggtttcaag tttctcttca gtgatttcac ccatgacacg gatagcaagt
     3001 cctggtcctg ggaatggttg gcgccatacg atatggtctg gcataccaag ctctgtacca
     3061 agagcacgaa cttcatcctt gtaaagagta ttgagtggtt caatcaattc aaactgcata
     3121 tcttctggaa gaccacccac gttgtggtgt gacttgatag tttgagctgt atccgtacca
     3181 gactcgataa catctgtata taaagtacct tgagcaagga atttcacatc tttgagcttg
     3241 cttgcttcgt catcgaatac atagacaaac tcgttaccga tgattttacg tttttgttca
     3301 gggtcagaaa cgccagcaag tttgtcaagg aaacgtttag cagcgtctgc tttgacgata
     3361 ttcaaaccaa acttaccacc gagcatgtcc ataacttgat cagcttcgcc tttacgaaga
     3421 agaccgtggt ctacgaagat acagatcaat tgatcgccaa tcgctttttg gagaagaacc
     3481 ccaacgacag atgagtcaac accacctgat agaccaagaa ggacacgttt atcaccgacg
     3541 gttttacgaa tttttttgat ctgcatgtca atgaaattat ccattgacca gtcaccttta
     3601 gccttacaaa tgttaagggc aaagttacga aggatatcat ttccgtatac agaatgacga
     3661 acttctgggt ggaattggat accgtaaatg tgtttatctg ggttttcgat ggctgcgtat
     3721 gggcagtcag ctgatgtacc tgtacgaaca aagtcagcag gaatctcagt aaccgcatca
     3781 ccatggctca tcaaaacagt ctgttcatca ggtgttgatt caaaaagcgc tgatggtgtg
     3841 tgagttaggg ttgattgacc gtattcacga tttccagcat cacctgcagg aacaactttt
     3901 cctccaagtt tatgggtcaa taactgcata ccataacaga ttcccaaaat tggaattccg
     3961 agttcgaaga tttctgggtc aatatcaaat gaaccatctt catatacaga atttggacca
     4021 cctgatagaa taattcctac aggattgact tcacgaactt caacagctga aattttatgg
     4081 ctttttagtt ctgaaaaaac accaatctca cggatacggc gtgaaatcag ctggttgtac
     4141 tggctaccat agtccaatac gatgattttt tctacatctt gcaaatcagt tgaaatgttg
     4201 ctcatctttt tcctttctca aaagaaatat cttttctcaa tattctatca caaataaggg
     4261 cgaattacca actaaacaag gcgaagtttg actttttcta gtttattggg gtacaataga
     4321 gaaaagatag aaatgaagtg aaaaatatgc tacctgctta tatgaaaatc catgatcaga
     4381 taaaaaagga tattgacgag caccgttggg ctattggtga gaggcttccc agtgaaagag
     4441 atttagctga gcagtttgcg gtcagtcgca tgaccctccg ccaagccgta tctctattag
     4501 tcgaagaagg cgtcttagag cgccgtgtag gaagcggcac ctttgtttcc agtactcgag
     4561 tacaagaaaa gatgcgaggg acaaccagtt ttactgaaat tgtcaaatcc caaggtaaag
     4621 ttccctctag ccagctcatt tcctacaaaa aaaccattcc caatgagcaa gaagttgcca
     4681 agctaggaat ttttccaacg gacaatatta tccgaatgga gcgggtccgc tatgccgacc
     4741 aagttcccct agtttatgaa gttgcttcta ttcctgaaaa attcattaag gactttaaaa
     4801 aagaagaaat caccagtcat ttcttccaaa ccttgcaaaa acatggctat cgtatcggta
     4861 aatcccaaca gaccatctat gctcgccttg ctaaagaaaa gattgcccac tatttggaag
     4921 ttgaaaaagg acatgctatt cttggattga cccagatttc ctacctagaa gatggtactg
     4981 cttttgaata cgtaaaaagt caatatgtag gcgaacgctt tgaattttat cttgaaaata
     5041 attagattac cacgcaaaaa ctctctgtca cggacaaaga gtctttttta tttttctaag
     5101 aataaatctt tcaaagaaat caaagttaca gcaaacaata tcattgccat accaagaaaa
     5161 tcaatgggat aaaattgttc attcattatt aagaaggcaa agaaaatcgc cgatattggc
     5221 tcaattgaag ccaacaagct tgacttgacc ggtcctatca gactggctcc tttaaggaaa
     5281 gctgtatagg caaagacagt cccgataagg ataatgcctg caaacgcaag gagaaaatca
     5341 agactagtcg ggatatcggc ctgtagaacc cctgtaaaag gaagggcgac caaacctgct
     5401 atgaccattc ccacaccaat gaccaagctg ctcccccact ttttaatcaa ggctatgggt
     5461 aaaatgatat acagagcata agtcaaggca gaaaagagac cccagaacag accagcaggt
     5521 gtcatggata actggtccaa ctgcccatgt gttgcgatca ggaaggttcc tccgatggcg
     5581 aatatgatgg aaactatctc tcccagtgtc ggtgccaccc tatccttgat acagctataa
     5641 attaaaattc cgacaggaca aacatactga agcaccgtcg ctgttcccgc attggtctcc
     5701 tgaatagcag acagataggc gaattggttg agaaaaagac caatcagagc aaaaataaga
     5761 agagacagca aactctttct atcctttaaa aagaccagta ttttatcctt tgcagtagca
     5821 taagccaaga gcatgagaat tccaccagcg attaaaagac gcaagttagt caagaccaga
     5881 gccgaaattc cgtgtgccat taggtattgg ccactcgttc ctgacaaccc ccaagcaata
     5941 ccagccacaa ctgttagtaa agtccctttt aaactatttg acatgtctct ccttactctt
     6001 ctttgcgaat caagttcatc acttgattgc ggtctaatat ccattgagct ctctcgtcct
     6061 tttcataggt acgattcgat agaaaaatag tggcttcttg cttctgacga ttccacatga
     6121 taaaggtacc tgtatagccc gtatggtcta gccaatctcc ttccaaattc catgctaaag
     6181 aacgttcctt gtcatccaaa ggagaaaaat tttgatttaa gtctcttgca aaatcatctg
     6241 ctaaatagtg ttctaaaaag atttgtaaat cctttatagt cgaaaataaa ccagcactcc
     6301 cagcatgtct acccaggaga cgagccttgg gatcatgcac tatgcctgcc tctacacctc
     6361 taactgttgg aacagcaagc tcaactggcc caaacttagt ttccgtcatt ccccaaggtt
     6421 tccagacttg atcctttaaa atcacatcca aatcttgatt aaaaattctt tccaaaataa
     6481 agcccaacag caaaaaatgg acatccgaat aaagaaaggc tggctgactt cgtctgttga
     6541 gatgaaacat cgcttccttt aattcagggg ctgttaaaag atcacgatta ggaataaaag
     6601 gatcaaggtc tgttgcatga gtcaagagct ggcgaatagt gatgtctgga taatcactct
     6661 caggtaaaaa atctattacc agtctatcaa tatctaattg acctatttcc cacaagaagg
     6721 tacaaactgt gccaacccca acaaccttgc tgacactagc taggtcataa actagtcctg
     6781 cctcagtctg caagccatgc tctggggcac tctggcctaa atagaactct gtccattgat
     6841 tgtccttaaa atacgcaaaa gaggctccgg gataaattcc tgcctcgatt tgttcttcta
     6901 tttttttaat aatcttggtc cacttcatac ttcttcaaac cacaattcaa cattatttct
     6961 atctttacca aggaagaatt tttcagactt aggaataaaa tattcagtag actcaaactt
     7021 ctggcgaaga cttgctatgt ctaattcatt gaccaagaac ttgagcatag ataagtccca
     7081 ggtaaccgta ttgtccacag tcaaatcctg cccctgagct ggaataaaat caagggatgc
     7141 cccaatttca gatgattcca agaaactttc gatatcagtt gggagatgta attccataga
     7201 aatctcaaat ttacttaaag aaattgatgc caaatctgtt tgaaattcag gcttttctcc
     7261 tacttctact agacttgctc tgtcatcttc cgcatgaatc aaaatcaaat catcttctgg
     7321 tgagaaaatt tcaaaagcgt agccattttg acctttatat aatcgatgaa tcgaatctgt
     7381 tttagataag attccttcaa tttctaaggg attttccacc ttgacaatca atctagctag
     7441 tttttttctt ccctctacct tacgagtacg catactggga gcttcttcta aaaccagctt
     7501 ttcaagaccc gtttggtcac ctagtgacag aaaggccgat tcttctaaca gggccttcat
     7561 tccaagggtt tcaatataaa atatttcatt taattttcta ttattagctt ttaaagtagg
     7621 aataatccgt acaatctgat ttacattcat aaattcctcc gtcacttttt attttaaagg
     7681 attttagaat tttttacaag atattatgct caaatttaac attatttagc tatttagtaa
     7741 agatagtctt tcaaggcttt tgacaaagcc tgataaccag caatactgag gtgcagtcca
     7801 tcagttgtat attctttttt gagttggcct gcttgatctg tcaaacaatc aaatactggc
     7861 acaaattcca cctgcatata ggcagatgca agctcttgat aggcttgatt ccaattctga
     7921 attttttcat tcgagcggat atagactgcc tgctggtact tctctccctc attgacaggc
     7981 aaaatggaaa gcaatttaat ctctgtcaat ggataatcgc gagcaacgga ttgaatgata
     8041 gcttcgagat tattgagagc ctcattcaca ggaacatcct ttccgatatc atttgtccca
     8101 atcagaagaa aaattttatc tactgctcca ccatatagat gagcatcaag gttctctagt
     8161 aacagtcctg tctgatagcc acgaattcct cgattgacaa tcgtctttga agtcccaaat
     8221 agctcctgta gaggataata ctcgacaatg gaatccccaa taaaaagaat gtttggttct
     8281 acaacagaaa tgtgatttag gtgacgatat ttggtttgaa ttttttcttg ttcctttagg
     8341 agccaatttt ctaataactg tactgccact tcattctcct ttttctaacc agttttccaa
     8401 gacttgataa actcctcctt ggctgttggc tggtgctaga gcagtcgcca cagctttggc
     8461 tttctcatca gcattttcca tcgcataggc aattccagcc atttcaagca tttcaacatc
     8521 attttcacta tcaccaaaag ccatgatttc ttgggatttc aagtcccagc gcttgagtaa
     8581 ttcctccaag ccccatgctt tatgaatccc agcttggagg atatcaatgc aaccatagcc
     8641 actggataca gctcggacac ggccatcaaa gagagcattg atttcttcca aaaccgaact
     8701 caaacgttcc tcaccaacaa ccatgctcat cttgagcaca ccaccaaaga ggtcagatgt
     8761 taattcatcc acaaattgca tccgttggta gaatttttca atcatttctg gagtcataaa
     8821 actttcaaga tctgtaaaaa tcgtaccttc cttgacaaaa tcacccttca tccccgttac
     8881 aacaaactgg tcctgacacg ctcgaccctt gaaatgagcc aaagccttgt tgacaatggc
     8941 gtcatcccat gtctgagcct gaatcaattc attgttttca aaaatacgag cgccattagc
     9001 aacaaccaga accactcgat ccaccaaggg actcagtagt tgtctcatgc ggtgaatttc
     9061 attgcccgtc gcaatgacaa aacgaatgcc cctttgatcc aactgatcta aaatcttttc
     9121 caatcgtggg agatcaagct gacctctagc atccagcaag gtcccatcca tatctgtcgc
     9181 aattacctta atcatcattt actttcctct ggattcaagc taataccact tcaatcccac
     9241 atgttcattc atttctttat aggctgtatc aattcgttcc ttagtcgctt catctaactg
     9301 gtcacgatga ctgccatcct ctataaaatc ttccaaaata taagtttggt aatgatacaa
     9361 gggatatcct tctggtgaaa aggttccctt tggtgttcga ttgacccaag taggatgagc
     9421 tttagctgtt ccgatagttg tttttccatc cttcttcttg atggtgacat ccatgagaac
     9481 accacgttca gtccacttag cattctcttc atctcccata gattcaattc gttgattgga
     9541 aatgaagttc cccatttaat agacaatgag cttcttatct ccatcttttt ccaccgtttc
     9601 agatggttca acaacgtgag gatgccctcc aaagataata tccgctcccc aatcgatcat
     9661 cttgtgataa agagcttttt gttcttcagt tggttccaat cgatactcaa cacccatctg
     9721 aagcatgata atggtgatat ctgcttcctt ctctgcccgt tcaatttcag ccttcatctt
     9781 atcttcgttt aaatctgaaa gataacgatt atagtcttcc ttagaaatat actgctcaat
     9841 tccattgaaa tcataggaat aggctaacaa tgcaaccttg ataccattca cttccttaat
     9901 gaccagcgga gcctgatcac gtggttcgtg cgtataaact ccgattggag tgattccagc
     9961 tttctcaata atatcggccg ttgaaataac tccctcaatt tgcgaatcca aaatatgatt
    10021 atgagctaaa tccagcacat gataacctgc ctccttaata gcatccataa cttcagcagg
    10081 agcattaaag agaagataac ccgctaaata atgatcctta ttaatggttc cttcaaaatc
    10141 accaatagct aaatctgctg cttagtcccc ttgcttgagc caaggagtca catactcaaa
    10201 attttcatga aagtcatagg taccgtcttc ttttttagct gaaaagaaaa gtccatcgtg
    10261 gtagagcaaa tccccgtggg ccataattct ggcagttttt tcctcttcct actcctgaga
    10321 cttttgctta gtcccctctt gagaaatagt atctcgtttt tgactagtca agggattcct
    10381 tggaagcttt caaacaacaa gaccaagccc attgataaat caactgctag caagagtatc
    10441 gccacaaatc ccttattgct ccacttgcga taactcctaa aaagtttacc aagcccttca
    10501 taaaacgaaa agctaaacca ccctgatttc gattttgtct tctttgtatc ttcgttctcc
    10561 ctactttctt atgcaagcct tttcttttta ttatatcaca gataagtatt tctttctcaa
    10621 ttgaattgaa cttcccatct attttctata aatcctaaat gccataatgc tttcaattct
    10681 tgtcattttg tgatatcatg tagaggaaat aaactaatcc acagtggctt attccaagta
    10741 taccacttgg gctttggcag tagctaactg cactaaacat aatataagga gagaaaatgt
    10801 ctgcaataga acgtattaca aaagctgctc acttaattga tatgaacgat attatccgtg
    10861 aagggaatcc tactctacgc acggttgctg aggaagtcac tttcccccta tctgaccagg
    10921 aaatcatcct aggcgaaaag atgatgcaat tccttaaaca ttcccaagat cctgtcatgg
    10981 ctgaaaaaat gggactccgc ggtggtgttg gactggctgc tccccagtta gatatctcaa
    11041 aacgcattat cgctgttttg gtacctaata ttgttgaaga aggcgaaact ccacaggaag
    11101 cctacgattt ggaagccatt atgtacaatc caaaaatcgt ctctcactct gttcaagatg
    11161 ctgctcttgg cgaaggagaa ggttgcctgt ctgttgaccg taacgtgcct ggctatgttg
    11221 ttcgccatgc ccgcgttact gttgactact ttgacaaaga tggagaaaaa caccgtatca
    11281 aactcaaagg ctacaactcc attgttgttc agcatgaaat tgaccacatt aacggtatca
    11341 tgttttacga tcgcatcaat gaaaaagacc catttgcagt taaagatggt ttactgattc
    11401 ttgaataaag aaaatcccgt tgcaagacgg ggttttgtgt tataatagag gcatgaaaac
    11461 aaatgatatt gtctatggtg tccacgccgt taccgaagcc ctccttgcaa atacaggaaa
    11521 caaactctac ctccaagaag atctccgagg taagaatgtt gagaaagtca aggaactagc
    11581 tacagaaaag aaggtgtcca tttcttggac atcaaaaaaa tctctctctg agatgactga
    11641 aggtgctgtt catcaaggtt ttgttctacg agtgtctgaa tttgcctata gcgagctaga
    11701 ttacatcctt gcaaaaacac gccaagaaga aaatccactt ctattgattc tagatggtct
    11761 aaccgatccc cataatctgg gttctatctt gcgaacagcc gatgcgacca atgtttcagg
    11821 tgtcatcatt cccaagcacc gtactgtcgg agtaactcct gtcgttgcca aaacagccac
    11881 aggtgctatt gaacacgttc caattgcccg agtgaccaac ctcagtcaaa ccttagataa
    11941 acttaaggat gaaggtttct ggacctttgg aacggatatg aacggtactc cttgccacaa
    12001 gtggaataca aaagggaaaa tcgccctcat cattggaaat gaaggaaaag gtatctctag
    12061 caacatcaaa aaacaagtcg atgagatgat taccattccg atgaatggac atgttcaaag
    12121 ccttaatgcc agtgttgctg cggccattct catgtacgaa gttttccgaa atagactata
    12181 aaaaagtttc cagtcatctg attggaaact tttttatgat taactatgtt ctgtaatgaa
    12241 tttataggct tcttgaccag cgatagctcc atctccaacc gctgttgtta cttggcgaag
    12301 gtctttcaag cgaacatctc caactgcaaa gataccgtcg actgcagttt tcatgtggtt
    12361 atctgtcaca atccatcctg cctgatcttg gatattcaat tctttaacaa aatcgctaag
    12421 agggtccaaa ccaacataga taaagacacc accgaaggct tgttctgtca cttgacctgt
    12481 tttcacattt tcaaatacga ctgattctac tcggttttca cccttgattt cccttactac
    12541 agaatcccag ataaagctga ttttttcatt cgcaaaggcg cgttcttgta aaaccttttg
    12601 ggcacgaagt tggtcacgac ggtgaacaat ggtaacagtc ttagcaaaac gagtcaagaa
    12661 gagggcttct tcaacagctg aatctccacc accaactacc aataaatctt ggtcacggaa
    12721 gaaagcacca tcacacacag cacagtaaga aacaccacga ctgttcagtt cttcttctcc
    12781 aggcactccc aaaggacggt gtttagaacc agttgctacg ataactgtac gtgtttcata
    12841 tgtttggtca tcagtcatca ctttcttaaa atcaccatgg tcttcgacat tttcaacata
    12901 accataaatg tgctccacac caagattttc aagtggttca aacatctttt cagccaattc
    12961 aggtccacta atattagcgt atcctgggta attttcgata tcagatgtat tattcatctg
    13021 accacctggc agaccacctt caatcaaagc tacttttaga ttgcttcgag cagcatacaa
    13081 ggccgcagtc atccctgcag gtccagcacc gataataata gtatcgtaca tatagattcc
    13141 ttctttcttg ttgtaactat ctttattcta actctttctt gtcaatcacg caaggattat
    13201 gccttgaaaa caagaattaa actcataacc gcaaaggata atactgggac aaccaagact
    13261 ccaatcataa tcatatcata gagatgggct tggcgagcct tggctgtctt atcaactccc
    13321 gacatggctc tcagaccaat ccaaatccct aaaaaaatca gaacaaggat ggtggtcaag
    13381 atcaaactct cgaaatataa agaaaatagt tgcagtagca tgatttctct catttctatc
    13441 ttttttaaag agtaaactca gctagtccaa ctaactgagt tttcctttat ctattatatc
    13501 aaatataagt ccgtttgtaa ctagcgaaga attcttttgt ccgctcttct ttaggggtgt
    13561 ggataatctc atccggtgtt ccagactcga tgattttccc cttatctaag aagagaatct
    13621 tatcagccac ttgggctaca aaggacatgt catgactaac caaaatcatg gtttgacctg
    13681 acttagcagc atctgcaata gacttttcta cttcaccaac caattctggg tcaagggctg
    13741 aagttggttc gtctaagagc aaaacatctg gtttcatagc aagcgcacgc gctagggcaa
    13801 cccgttgctt ctgtccacct gataaatggc gaggataatg gttttcacgg tccgaaagcc
    13861 caaccttagc caactcttcc ttggcaatct tagtcgcttc ttggtcagat aatttcttga
    13921 caacaaccaa gccttctttc acattatcaa gtgctgttcg gcgttcaaac aaattaaact
    13981 gttggaaaac catagacaac ttacgacgta gggcaaggat ttcttcttga gtgattttag
    14041 aaaaatcaac tgaaaaacca tcaatctgaa tagagccact gtcaggtgtt tcaagataat
    14101 tgagactgcg aagaaaggtt gattttccag ctcctgaaga accaatcaag gctacaactt
    14161 cccctttttg aatatccaag tccagatgat ccaagacagt ctgtcctgaa aaggatttgc
    14221 ttaaatttga aatcttaatc attaacgaag gtctcctttc acatctgttt gcactgtatc
    14281 aggtgcagaa atagccattt ttctctcgat gaaacgaccg aggctttcaa ttccgatatt
    14341 gactacccaa taaacaaggg caacggagat gaagcgttca aaatagcgat aatcagctcc
    14401 acctagaatc tgagcttggg caaagacttc cacaacaccc gcactaaaag ctagagatgt
    14461 tcccttggtc aaaccgatga gggaattaat caaggttgga gtagctacca ccgctgcatt
    14521 aggaataatc actcgtcgat aaacttgcgc tcgggtcata cccagactgc gtgccgcctc
    14581 aatctcacca ggattaactg agagaatggc tgcacgaatg gtttcactag cataagctgc
    14641 ctcattaaag gcaaaagcga caatcgcaaa agctgcagct ggaatcgcat tgatattgag
    14701 accagttccc cattgctgat tgagggcttt caaagccaaa gggattccgt agtaggtcaa
    14761 catgagttgc accaaaatcg gtgtcccttt taagaaacta acaaagaagg cctgcaaggg
    14821 atataaaatc ttgacacgat tgatcttcac aatggcaaaa agaagcgcca aaaccaagcc
    14881 aaaaagggca ccaccaattg tcaacataat tgttgttgga agttgttgga caattctagg
    14941 gattccatca aagaccgaac gtaggctaaa cagcttgcca tccggaatca attgcatcaa
    15001 gttttggtac caatctgatg ctaaaatcgt tgtaacattc ataaaaacat cctcttctga
    15061 taatgattca ttctaccatg cttctgccgt caatgaaatt atttgctacg gtcagataca
    15121 gactttgtct acctactagt ttatcatact ttgaaacagg gaagttatat attttatcta
    15181 tcaaagagat agataaaaac tatttcagtc ccagttcttc ataagatttt cgataaccga
    15241 tttgcttaac agttccattt tctactaaaa tgggccgttt taacaacata ccgtcacttg
    15301 ctagcaactc agccgcttct tggtttgaca aacttcctac cttatctttt agccctaatt
    15361 cacggtattt gataccactg gtgttgaaaa attgcttcaa ttcaaatcct gaggtttcta
    15421 gccaattcaa aatgacttct tggctaggtg tttcttccac gatatggacg gctttatagt
    15481 ccacacctaa ttgatttaat tcttgttttg cttttttaca agttgaacat ttggggtatt
    15541 cgataaattc taacatgtgc ttctccttct atttgtttat atctttaaaa tctacgcctt
    15601 catgctccaa gagccaagct ttcttttcca ctcctgcagc atagcctgtc agacgcttgc
    15661 ctgctcccaa cacacgatga caaggtacta ggatagacca aggattgcgt cccactgctc
    15721 caccaattgc ttgagcagaa gccacttgca ggtcttgagc aatttgtcca taggtcactg
    15781 tctgaccata aggaattccc tgtaaatagg accaaactct cttttcaaaa ttcgttccaa
    15841 ttggcgccaa gagcaagttg gataaatcct gaggctcgcc tttaaagtaa tcatctaagc
    15901 aagcaataac tgggtctaaa ataggatgac taacaacttc ttctatcgtt tcatctccta
    15961 gtcccctctc aaaatgcttc tgctcctgaa cccaaattcc atacaaataa tggtcatcag
    16021 ctacaagtga tagaatacca attggtgagg agtagagtat ttttacatac ttcttttgca
    16081 ttatttcttt aatttttgat aggccaagcg ttcgccatct actggcacct taccaacttg
    16141 tttaaaacca agtttttcaa aaatatgttg cataaccttg ttttcagcat gcgtatctga
    16201 gcgaaaatca agataatcaa aaccttcaat caagccctct aagaaggttt gagcaactcc
    16261 ttttccctgc acatctgctg ccacagcaat acggtgaaag actagatact ctgactctcc
    16321 agcttgccag tttccctcat aaatagcttc ataggcctcc tctggactct tggtcacagc
    16381 agcataggct agcagttctc cctcttccaa ggctacgtag gcttgccctg agataatatc
    16441 atcgataata acatctgcat ttggatagcc attttgccac tggtcactac cagcatctgc
    16501 taaacatttt ttggcatcct ccatcacctg catgatggca tctacttcat ttggaaaagc
    16561 taaacgaatt tccatctttt ttcctcattt ctgactagtt tctcccatca tagcataatt
    16621 taagtatttc tacaagcagt taaaacttga ctttgtgttt ttgttatttt ataatctagt
    16681 tatcaaaact atataaaaag gagttgaaaa tgaaaactac cttttcctac ccaaaatggg
    16741 cagaaattcc aaacattgac ctctatctgg accaggtttt gctctatgtc aatcaggtct
    16801 gcgcccctat ctctcctaat aaagacaagg gcctaacagc atctatggtc aacaattatg
    16861 tgaaaaatgg ttacctgaca aagcctgaca aaaaaaaata ccaacgccaa cagattgccc
    16921 gtttgattgc tatcacaacc ctcaagtctg tattttctat tcaagaaata gcccagacac
    16981 ttaatactct acaaactcaa gcaagttcag accaactcta cgatgctttt gtggactaca
    17041 tgaaccaagg aattgaccca gctaacccta ttatccaaac cagctgccaa accgttaaac
    17101 tctatcatca aactctagac ttaatcgatc atactcaaga ggaggtaatc caatgaacac
    17161 tagtcttaaa ctcagcaaac aactcagttt tggagaggag attgctaata gcgtgaccca
    17221 tgctgtgggt gcagtcatca tgcttatctt gctgcctatt tcatccatct atagttatga
    17281 agcacacgga tttttatcct ctatcggcgt ttccattttc gtcatcagtc tctttctcat
    17341 gttcctatca tccaccattt atcactctat ggcctatggt tcgacccaca aatatgtttt
    17401 gcgaatcatt gaccattcta tgatttacgt tgccattgcc ggctcataca cgcccgttgt
    17461 cttgaccttg atgaataact ggtttggcta tctgattatt gtcatccaat ggggaacgac
    17521 catctttggt attctctata aaatctttgc taaaaaggtc aatgagaaat ttagccttgc
    17581 tctttacctg attatgggct ggttggttct ggttatcatt cctgccatta tcaatcaaac
    17641 gacacccgtt ttctggagtc tcatggtaac tggcggactc tgttatacag ttggagctgg
    17701 attttatgcc aagaaaaaac cttatttcca catgatttgg catctcttta tcctagctgc
    17761 gtccgtactc caatacatcg ctattgttta ttacatgtaa aaaagttgag aaattcaatc
    17821 tcaacttttt tctttacaca tattgataaa gtactggtgc aagcgcacat catcagtcaa
    17881 ttctggatga aaagaactta ccaacatatt tttttcttgg gctgcaacaa tttgattgtt
    17941 cactgttgct agaatttcta caccctcacc aacactactg ataatcggac cacggataaa
    18001 ggtcattgga atcttgccaa ctcccttaca ttctgcttcc gtgtagaaac ttcctaattg
    18061 gcgcccataa gcattacgct cgaccaccat atccatagtt cctagatgac tctctttctg
    18121 agaagtgatt tccttagcca acaaaattaa gcccgcacag gtcccaaaca ctggtaagcc
    18181 agatagaatg gcttctcgga tgggaagtag catgttctgg tcacgtaaga gcttgcccat
    18241 ggttgtagac tcaccaccag gcaaaatcaa acccgacaag tcactctgat cttgctgaaa
    18301 atcatctaga tttctgagtt ctacactctc gacacctaat tgatctagca cttttgcatg
    18361 ttctgcaaag gccccttgca aggccaatat tccgattttc atctattttc ctcgttcagc
    18421 catgagaatt tggatttcat tttcattaat accaaccatg gcttctccta aatcttcaga
    18481 gatttgagct aggatttgag gattacggaa gttagtcaca gccttaacaa tggcactcgc
    18541 tcgtttaaca ggatctcctg acttgaaaat acctgaaccg acaaagaccc cctctgcccc
    18601 tagttgcatc attaacgcag catctgctgg cgttgcaaca cctccagcag cgaaatttac
    18661 aactggcaat tttccatgtt catgaacata ttggaccaat tctacaggga cttgcaaatc
    18721 cttggcagca acataaagct cgtcctcacg taagttttga atgcggcgaa tttcctgatt
    18781 catcatacgc atatgacgaa cagcttggac gatatcccct gtccctggtt ctcctttggt
    18841 acgaatcatg gaagcacctt cagcgatacg acgcaaggct tcacccaaat ccttagcacc
    18901 acagacaaaa ggaacttgga attctttctt gtccacatgg aaacggtcat cagctggaga
    18961 tagaacttca ctctcgtcga tataatcaat ttcaatagcc tctaaaatct gagcttcaac
    19021 aaaatgcccg attctgacct tagccattac tggaatacta accgcttctt ggatttcctt
    19081 aatcatcttt gggtcgctca tgcgggaaac tcctccagct gcacgaatat cagccggaat
    19141 tcgttccaag gccatcacag ctgccgcacc agcagcttct gcgatacgag cctgttcagg
    19201 attctgcaca tccataataa caccaccctt gagcatctgt gccaagtttt tatttagttc
    19261 ataacgattt tcagtcattt gttttatcct catcatttgt attggtagct accttttcat
    19321 tttaagtcag aacagaatga agcacaagat aaaaaaacta taattgtatg gggacagatt
    19381 agctaaaaac tatctgacct taacttaagg ccagatagct cattcatttt tatttttcag
    19441 ccgtaagggc agccattgtg atgtagttgt atggtttgtt gaagtgtggc aagaagaaga
    19501 ggtctgtcaa tgccaattta tcaattgtca catgctcttg gatagcaagt gagaacatgt
    19561 ggattcccat gctaattgca atatcatgtg aaaccatttg ggcaccaaga atttcacggc
    19621 tatctttgtc aaagacaatc ttaattgcta cttcatggtt gtcatgtttc atgaattctg
    19681 gtttttgaag atcgttaaag cctgtttcag ttgcgttgta accagcagct ttcgcttttt
    19741 caagagtcaa accagttgaa accatgtgaa gaccgtagat tgagatacca tttgaacctt
    19801 gaacaccgat tccttccaat tcatgtccac aagcgttgta ggcaccaacg ataccagtgc
    19861 gaacagcatt tgaagcaaga gcgatatagc ttgtatcttt acgagcattg tcataaacag
    19921 tcgcacagtc accaacagcg taaacgcctg ggatagatgt ttcttgtttc ttgtctacaa
    19981 ggaaggcacc gttgcggaag agttcgatct taccatctgc aagggctgtg tttggacgga
    20041 aaccaactgc aaggataacc atatccacgt caaagctttc tttgtcagta atcaagcgtt
    20101 caactttacc gtcaccttcg attgctttaa cagtttgacc tagagccaag cggatgttgt
    20161 gatcttccaa gttcttcgcc atcatttgtg tgaagtcttt gtcatagtaa ccgttcaaga
    20221 cagtatcaac gatatcaaca aggacaactt cttttccaag acgttcaaag gcttcagcaa
    20281 gttcaacacc gatgtaacca ccaccaacaa cggcgatacg gtcgaggtgt tggctcttgt
    20341 cagaaagttt attgataact tcttcagcat tttggtacaa tttcacgaat tgtacgtttt
    20401 caagagttgc tttaaattcg cggtttcctt taacaatttc aacaccttcg attggtggca
    20461 agattggtgt agaacctgta gcgaaaatca atttttcgta tgattctttg tgctcttttc
    20521 cttcaacttc cgctgtaact actttgttat catagtcgat tgaaagaaca ggtgagttca
    20581 tgtaaacttt agcaccttta gcttccaatt tttctttatc agaatagaac aagccttcag
    20641 caccgtcaat ttgttcacca atccaaagag ccattccaca tcctaggaaa gagatgttag
    20701 agttttggtc aaatacaaca atttcgttct catttccaaa attatccaac atggtattga
    20761 tacatgctgt accagcgtgg ttagcaccga ctacaacgat tttactcata aaaatttcct
    20821 gccttcattc taaatttacc ttactagtat accatttacc gttagcgttt acaagggggg
    20881 gactattatt tcagcatttt ttatcaaaaa taattcccca tttatcctgt tttcaagcct
    20941 catgaatttt atgagcatat ttcttgactt tttccaaatt ttgtttgtga aaattctaac
    21001 tttatggtat tataataaca tgaaaatgaa atgtaagggc ttcaatttag atgattattt
    21061 gatattacaa cttattttct ataagagaaa ggagttggta gcttgactct tcgttcacat
    21121 tctgaacggc taatggggac tactatcact atttcattag tggatgagca agccgatatc
    21181 tttctccaaa aatcctttga cttgctcaaa gaacttgaat accgcttcaa cgccaatagt
    21241 caagaatctg agttgatgga aatcaattat caagcaggaa tagcccccgt cacggttcat
    21301 ccagacctgt ttgagctgat ttcacttggg ttagagcata gcctagcgct ctctagccac
    21361 ctcaatatca gcattggtcc cttaattcaa acctggcgta tcggtttttc agatgccaaa
    21421 gtcgcccagc ctcaagaaat tgaatcggtg ctgcctctaa tcaatcctca tggtatcgag
    21481 ttagattctt ctacttctac tgtgttttta aaacagaaag gaatgaagat cgatctaggt
    21541 tgtttagcca aaggatacag tgcggataag gttgcccaat ttcttaggaa agagggggtg
    21601 acttctgcct tgatcaatct gggagggaat atcttgacca ttggaaaaaa tcaggcaaga
    21661 ggggataacc catggcaaat cgggattcaa gacccagcca atcctagggg aaatcattta
    21721 atgaccatcc ctgttgtcaa taaatctgtc gtgacttcag gcatttatga acgtcacctg
    21781 accgtcgatg gacaagatta ccatcacatt tttgacagtc aaacaggata tcctgttgaa
    21841 acggaactag cgagtctaac aatcatctct gataaatcag tcgatggcga aatctggacg
    21901 actcgactct ttggagaaag acctgcttct atcctctggc aagtcgaaag tttggagggc
    21961 atcgaagtca tcctcatcga taaagaaggc cacctaagct gttcttcagg aattcctact
    22021 ctatagagac aactgtttca atggaatttt aaaattgtat tatgtaaaaa gagaaaggaa
    22081 atctcatgtt aaaacttatt gctattgttg gaacaaattc aaaacgttct acaaaccgtc
    22141 aattgcttca atacatgcaa aaacactttg ctgacaaagc tgaaattgag cttgttgaaa
    22201 tcaaggccat tcctgtcttc aacaaaccag ctgacaagca agtacctgct gaaatattgg
    22261 aaattgctgc taaaatcgaa gagacagatg gcgttattat cggtactcct gagtatgatc
    22321 actctattcc agctgttttg atgagcgctc ttgcttggtt gtcttatggt atttacccac
    22381 ttttgaacaa accaatcatg attacaggtg cttcttacgg tacgcttggt tcatctcgtg
    22441 cccaattgca acttcgtcaa atcttgaatg ctcctgaaat caaggcaaat gttcttccag
    22501 atgaattctt gctctcacac tctcttcaag catttaaccc aagtggcgac ttggttgacc
    22561 ttgatgttat caagaaattg gatgccatct ttgatgactt ccgtatcttt gtaaaaatca
    22621 cagaaaaatt acgtaatgca caagaattac ttcgcaaaga tgctgaagac tttgactggg
    22681 aaaatttgta agataggaga ccaaaaagaa tgaaatttgt tggacttgtt ggatcaaact
    22741 acgatcaatc atataaccgt aagctcttgg aatttatccg tcgctacttc aaactcaaat
    22801 ttgaattaga agttcttgaa attgacgaag ttccaatgtt taaccaagat gaaaaatggg
    22861 atgaaagttt ccaattacgt tatttatata acaaaattac tcgtgcagat ggtgttatca
    22921 ttgctactcc tgagcataac cacactatct cagcttcact caaatctgta cttgaatggc
    22981 tttcatacga agttcatcca tttgaaaaca agcctgttat gattgtgggt gcatcatact
    23041 atgaccaagg aacatcacgt gctcaagttc accttcgtaa aatccttgat gctccaggtg
    23101 ttaatgccta cacgcttcca ggtaacgaat tccttcttgg taaagctaag gaagcttttg
    23161 ataacaacgg aaatatcacc aacgaaggca ctgttaaatt ccttgaaatt tgcttagata
    23221 actttgttaa atacgtagga gtcgtttcga aattgaaaaa accaaaacca atcgaatcag
    23281 aagacttgga ttgtggaaaa ccaatcgcta caaccatcac agaagttgac cctgacgatc
    23341 cagaatgggt agaaaaagtt gcagcaatca ctggtgctgt ttctggtgat acctatgtca
    23401 aattggacca cggtatccta acagttaacc aaattgatat gttcttgaaa gctatgccat
    23461 ttgaattgac atacgctgac gataacaacc aattcctcta ctacaacaac gctcaccaag
    23521 atccagacac tatgttcgct aaacgtgtac cacctcaatc aggtagccgt atgtcgactg
    23581 ttcatggttc tcttccacca gcacgtatga agaacgtaga gtgggttatc ggaacacttc
    23641 gcaacggaaa ccaagaatac gtccgtacga tcgttccagg ttctcctgca ggtgttatca
    23701 acactcacaa ctaccaagca atgtactatc ctgatggatc atacgctggt atcaatgaaa
    23761 tcgtctttaa cttccaacca tggcttgact ggtacctaaa agagactggt caacgtttgg
    23821 tgggtggtag cggaccattt gctcctgctg ccggaggtca tggagacgcc gatgctactt
    23881 ctggcgcttc tgattcaggg gatgctggag gccacggtgg tgacgcagac gctacagccg
    23941 gtgcaagtta ctaatgatag tttttaggaa ccattatggt tcctttttta gcgaaaaaag
    24001 actagcaaac acaaactgct agtctctttg ttatcgtttc atctatcctt gttaaaagaa
    24061 agaatactta tactcaatga aaatcaaaga gcaaactagg aagctagccg caggctgtac
    24121 ttaagtacgg caaggtgaag ctgacgtggt ttgaatttga ttttcgaaga gtattattat
    24181 gaatttgggt catcaagact acggccatgt aatccttttt cacgttgtac ttggcgtagt
    24241 ttttctggtg taacatcgtt tccttcttcg tccacaattt taattccttc aatgtggtga
    24301 cgaacagcgc ggcgataacc ttcgatgtac tcctcacgta gtttggcttg ttccactttt
    24361 tcttctgatg ttaagccttc tgtttttttc tttttagcaa gctcattgat acgagcaatt
    24421 tttttcggat ccatttcttc tcctttgtaa taagataaag tccgtttatc aaattttatt
    24481 tagtgttaat ttggttaaaa caagcaaact tagctgcttt cttggttagt tgtgacaaga
    24541 ttgccaaacg attttgacgg acagcctgat cttcagccat taccatagta ttttcaaaga
    24601 aagcatcaat gactgggcta agcgcaaaga gttgtttcaa ttgctgactt gcaggtcctg
    24661 ataaaacgag tgtttctact gcttctgcca aagctttttc ttggtcattc tcaaatagtg
    24721 ctgaatcaac cgtagcaacc ccttctgcct tctcagccag gttaaaggca cgagaaagtg
    24781 attcaacaga tggtttaaaa tcttcttcct tgcttacttc tacgagagca cttgctgctt
    24841 ccaacatatc tgccacaaca aagtttgaac ctgcaagaac tgcttccttg atatcttttg
    24901 gagtagagcc catcatctta tcaacacgag ccttgataaa gtccataacc tctgctttat
    24961 tttcataagt caaactgtca aatttcaatg cataaaggct atcaatcagc tcatccatag
    25021 caatgtgcca accaaaggca tccaagatac gaaccacacc ttgagttgca cgacgaaggg
    25081 cataagggtc attagaacct gatggaatca atcctactga gaagaaactc aaaatcgtat
    25141 ccaatttgtc tgcaatggct agaactgcac cgaccttgct ctctggaagt tctccttcag
    25201 ctgatgtagg catgtagtgt tcacgaatag cagctgccac cgctggagtt tcaccagcaa
    25261 gaagggtgta tttttcaccc ataattcctt ggagttcgtc aaattcacca accatacctg
    25321 tcaacaagtc aaacttgtaa atggctgctg cacgagcaag gtcaactgtt tcatccactg
    25381 acaaaccagc tttttctgcc aaaagtacag tgatttgacc cgtacgaatc atgtgttcac
    25441 gaagggaacc aatcttctca tggaaggtga cattgtttaa tttttcaaca agatctgaaa
    25501 tcaccaattt ttggtcttca cgccagaaga attctccgtc ttctaagcga gcgaccaaga
    25561 ctttttcatt acctttgatg acattttcca aatgctctgc atttccgtta cgaacagaaa
    25621 taaagtttgg caatagttta ccgtcttgat cacggacaac aaagtaccgt tggtgttctt
    25681 tcatcgaagt caccaaaact tcttctggga cttcaaggta tttggcatca aaacttccca
    25741 taaaggcagt tgggtattca accaagttca agacttcatt cagcaaatca gcatcaatct
    25801 caatacgtac accacgctca gcttcgattg tcttgatttg gtcaacaatc atttgctcac
    25861 gttcacatgg atctgcgatt acaaactgct tacgaaggtc ttcttcatag ctcaatgctg
    25921 actgaatctt ggtttcttgt cccaaaaaac gatgaccacg actcacacga cctcccttga
    25981 tatcaaggaa atccaaatca aactcttctt catctaaaag aacagttaaa gtgtggacag
    26041 gacgaatgta ttcaaagcta tttcccgccc agtgcatgct gacagggaaa gtcaatgact
    26101 tcaagacatc tacaacacca ggaacaatgg cttcaactgc ttgaccaact tcttccttag
    26161 tgacatagac atattcttca cccttgattt cacggaattc gatatcttca acagtcaagc
    26221 cttttccacg gacaaatcct tgagctgctt tggtgaagtt tccatcacta tccaaggcaa
    26281 ttttctttgc tggtcccttg aaatcttctg tcaaatcaga ctgtttgtct gataaaccag
    26341 tcacacgaac agccaaacga cgtggtgttg agaaggtttg aatggcttca aaagacaggc
    26401 ggttttcctt gaggaaggct gccatttttt cgcctagttg tttttcactt ggtgtgacaa
    26461 cataggctgg taattcttca agaccgagtt ctactaataa gttttttgtc atgttttttc
    26521 ctttacattt tcttcaatct tttttgatat gcaccttagg tactggggac gtcgctaact
    26581 aactctgtga gtctgtatgg aaatccaatg ctaaatttat caagatttcc aacaatctca
    26641 tcaaagtgga tttatctgac tgatttttga acctaaggtt tcaaaaatcc ccacataaca
    26701 gtacggcggt gcatatccct ctagcaagtc ttcgacttgc ctctaacgat tttagagtac
    26761 agtattactc actattctgc gtcttctgct aaaagtttag ctcgtgtttc ttcatccaaa
    26821 agtgggtaac ctaggcgttt gcgttctgca acaaaggttt tggctacaac acgggccaag
    26881 ttacggatac gagcgatata gcctgcacgc tctgttacag atacggcacc acgcgcgtca
    26941 agcagattaa aggtatgtga acatttgaga acatagtcat aggcagggtg taccaagcct
    27001 tcttctaatg cacgaccagc ttctttttca aacttatcaa agttttcaag caacatttct
    27061 tggtccgaaa tttcaaatga atattttgag tgctcatact caggctggat aaagatttct
    27121 ccgtatttta caccatcagc ccactcgata tcatagacag agtctacttc ttgaatgtaa
    27181 gaagccaagc gctccaaacc ataggtaact tccgcagtca cagggccagt tgccaatcca
    27241 ccgacttgtt ggaaataagt gaactgagtg atttccattc cgtcaagcca aacttcccaa
    27301 ccaagaccag ctgaaccagt tgatgggttt tcccagttgt cctcaacaaa acgaatatcg
    27361 tgctccaaag gattgattcc cagtttttcc aaagactcaa ggtaaagttc ttggatattt
    27421 gatggagaag gcttcatgac cacctggaat tggtggtgtt ggtagagacg gttagggttt
    27481 tccccataac gaccgtcagc aggacgacgt gatggctcta cataagctgc attccatggc
    27541 tcaggtccga tagcacgaag gaaagtgtaa ggactcattg tccccgcacc tttttcattg
    27601 tcataagcct gcataagcat acaaccttgg tcattccaaa atcgttgcaa agtaaggatg
    27661 atttcctgga aagtcaattt cttagacatt gtttactcct ttttatataa attacttgcg
    27721 acacgagtct gcctcgtcga tcatacgagg caagacgagt tagtactgcg tctagctcag
    27781 caccctagtg ctgagcgtgg ggcagtccga ctgtaaggag gtctctgcca ctgatgcagt
    27841 gaaatgttaa tttcttagac attgtttact cctttagttt ttatatttct ttttcaatta
    27901 atttctgctg aacaaaccaa tctaacaagg gaaaagtttt ttctgtattt gcccataaat
    27961 gataagaatc aaagaccgct tgtacactac ctaaattttc taccaactta tctactgtca
    28021 aaaaactgcg ccagtattca taaaaaatac ttgcatagtt cttatcataa gtagaggaac
    28081 caaaatcatt caatgaatgc caaccatact tcttctgaaa aagttctacg agagattgat
    28141 tacaaatttt ttccgcttga aattcctctt ctgtcaagaa atacttgcga ctaatatatt
    28201 caaccatccc ctcttcgaac cagatataag agtcataacc atcaaaatca tctaaaaaat
    28261 gctccgacca atgagctaac tcatgtccta caatctgtaa gaggaaattt tcagataaag
    28321 aatgatagtg actttctatt gcttgagttt gctcagaaca ctcgtagtcc atcaattgat
    28381 acaaatacaa ctctttccaa acagctaaat caggcgtcat aaccattcgt ctattatttg
    28441 tataggctgg aacagcgctt tccctaataa tctgtgtagc agcattaaaa tctgaccaaa
    28501 taacggcttg cggtaaatca cagactgcaa gttcattctt taaaaaagat tgataatctt
    28561 tcaacttttc agtatttctt actacaaaat cacgaaatgt agctagttga ctatcgtctt
    28621 ttacaagata aaggttgtcc acggctctcc tttctttcac acaatagact gaataagcaa
    28681 aagaaccaca tctgacaatc ctaggttgat ttaacctagg ggcgtcagaa acgcggttcc
    28741 accctaattt attacttcat tgtttttaaa aatactacag aaagcgccag ctcattattt
    28801 tgccctactt ggctcccact atcccaagct cgcttgaaga acgccataag actttctttc
    28861 ttgctgacta ttatatcaaa aattagaata atgtacaatt ctttttatga ttttctagaa
    28921 atccacatca tcaactcgtg gagcacccga ttgaacagca atcgttttta aggtttctct
    28981 ctcctcatga ctcagttcaa ttccaaagca atcaagatta gcttgaatac gagaggttgt
    29041 gacagatttt ggaagtggta aaaatccttc tgccaagctc caggccaagg ctatctgagc
    29101 aatcgatttt ccgtgatttg ctgcgatttc ttgcacttgc ttgctatcaa atagttctcc
    29161 ctgaccaaaa ggcccccaag cttccaataa aattcccttt tcacgacagt aagctacgac
    29221 ttgatcttga tacacacctg gcgccaagcg aacttgattg accgcaggaa cgatagttgc
    29281 agtttcaagc aaggcatcca aatgatgggg aagaaaattg ctaacgccga tagcacggat
    29341 tttcccttct tgatagaggt cttccatcgc tctccaaact tccgcattgc gagttttcca
    29401 tgcgtcattt tctctgagcg gttttgggtt cggccaatga atcaaataca aatccaaata
    29461 atccaagccc agtttttcta tagatttttc caaagcttga cgagtttgct cataggtttg
    29521 ctgactattc caaagcttgg tagttacgaa catttcttca cgtggaactc cgctatcttt
    29581 gattgcttga ccaacacttt cttcattctg ataaatcgcc gccgtatcaa tatgacgata
    29641 accagccttc aaggcttcta acactgcacg ataggcttct tctccatcct tagccttaaa
    29701 agttccaaat cccaatactg gaatttctac tccattattt aattgatagg tattcatatg
    29761 cttctccttc tattttattc atcaattata gcataaaaca ttttttaagt agtactatct
    29821 tctgtaaaaa ataagtctgt caaatatcta acagacctat tttttcttgc ttattcatca
    29881 cgactatagt acagctcatg agcttttagg cgagtattga gcatctctgg tatggtcaca
    29941 aaggtataac cttgattttt caaatactca atgacccttg gcaaggcatt gactgtcgga
    30001 ctgtgaatat catgcatcaa aacgatagag ccgttagcta cttgatgctg aatttctgtc
    30061 aaaatagatg cttcattttt actcttccag tccagactat ccacatccca catgataaag
    30121 ctcaaatcca agctattgcg aatatcatct gtaatagcac cataaggtgg acgcatgagt
    30181 ttagaactag aacccagcac tttagttagc acatcctcag tatcagtaat ctgcttttta
    30241 gcttcatcaa gagagagttg cgagagaatc ggatggctcc aactatggtt tccaacaaca
    30301 tgaccttcag attttatcct cttcaccaag tcctcattcc cagaaacatt tttcccaagc
    30361 acaaagaaag tcgctttaat atcatattta gctagggtct ctaatacctg cggggtcgtt
    30421 gctggatttg gaccatcatc aaaggttaga gcgacaactt tttgatattt cttatcaaag
    30481 taagattggt acaaggccgc atctttttcg agtaagtacg aagattggat aacatcaaag
    30541 aaagcagata ctggcaaggc tatctcttct aaattttcaa ccacaggact tggataaagg
    30601 ataatctgac tatccttgta atcaaaattc catgcagaca agtcttggtc agagaagttt
    30661 tttacaatct gctcactctg gtcttgctct atttttttat cctctatgaa ggaggtcaac
    30721 tcttttatca gctgttcctt agccttacta gcatctgaaa acagttggtc aagtgtaaaa
    30781 ggttgcccat cttctgttaa gtgaaccttt cctagactgg tcttttcagt ctcttcaacc
    30841 ttaaaagcaa ctaaatcata gatttgtttg gtcacattac gattaacgac tccctttaaa
    30901 cctgactctt cttgctctgt atagtagaaa acaagattgt ccttactttc tagcttgtcc
    30961 ttaacatctt gatttatcaa ctccctaaca gaggaaatca ctttctcccc ttggagagga
    31021 taataggcaa tcacttcggc ttgcccctga cgaaaatgct ccttctgatt tccctcactc
    31081 aattgatcat ctttctcttt tttgagcgat tcaatctttt gctcaaaact tttttgctgg
    31141 tagatcttaa aagcaataaa tccgcctaat aggcaaatag aaattgctaa aataccaatc
    31201 aaagccaata atacatgtct cgttttcccg tgtctgccac gtcctagtct acttttattc
    31261 atatttatat cataacaaat ttgagcaata atttcaatga tacaatttgg caatccacaa
    31321 ttcctctagc aagccaaagc atcttacatc aactccaaca tccgtatctg tagagattat
    31381 gtagttttct atctatggaa tttctagtag attgaagcta gaatagtaga cctatacttc
    31441 taaaacattg ttagaaatcg atttgattgt cctgatcgat ttgtcctgtt cttatttcat
    31501 tttactataa aactatgaga agctaggtca tctgagaagt aattactatc gacaattgcg
    31561 atagcgtata ctggtgcaat ttgtttgtag ctctggtggg tatcaccttc acgttggcga
    31621 attttttcta ggttttgatt aacctgactg cacagataag cccataggcg attgatgaaa
    31681 aaattctgat gatgaacctg aatttcgatg ataacttggg ttccattatc taactccgcc
    31741 aagacatcta tactagtata gaaatcctgc gctgagtagg gcatggaagg caagacgtga
    31801 atgttacttc cctccaaaat cgtcacattt tttgctggca agtccagcat atcgcggata
    31861 aattgacaaa gcattagttg ggctgatacc cggatgtctg agaatcctcc ttttcctcct
    31921 ttttctcctc tctgttggat agtcccgtct atctatgtta taataaaaga aggatttaaa
    31981 atcggaaaag gagtatttat gctaaaatta ggtgtcatcg gaactggcgc tatcagccat
    32041 catttcatag aagcagccca taccagtgga gaataccaac tggtcgcaat ctattctaga
    32101 aaactagaaa ctgcagcaac ctttgcttct cgctatcaga atatccaact attcgatcaa
    32161 ttagaagtct tcttcaaatc ttcttttgat ttagtctata tcgccagtcc aaactcctta
    32221 cattttgctc aggcaaaagc tgccttgtct gctggtaaac atgttattct cgaaaagcca
    32281 gctgtcactc aaccacaaga atggtttgat ttgattcaaa cagctgaaaa aaataactgt
    32341 tttatctttg aagcagctcg taattaccac gagaaagcct ttactactat caaaaacttt
    32401 ttagcagata agcaagtgtt aggagcagat ttcaactatg ccaaatactc ttccaagatg
    32461 cctgacttgt tgactggaca aacaccaaat gtcttttcag accgttttgc tggtggagcc
    32521 ctcatggatt tggggattta tcccctctat gctgctgttc gtctttttga aaaagctaat
    32581 gacgcgactt accatgctca acagcttgac aatagcattg acctaaatgg agatggtatc
    32641 ctcttctacc cagactatca agttcacatc aaggctggaa aaaacatcac ttccaatctt
    32701 ccttgcgaga tttatacaac agatggaacc ttgactctca acacgattga gcatattcgc
    32761 tcagctattt ttaccgacca ccaaggaaat caagtccagc ttcctatcca acaggctcct
    32821 catacgatga ctgaggaagt cgctgcattt gcacacatga tccagcaacc agatctgaat
    32881 ctctaccaaa cttggctgta tgatgcaggc tctgttcatg agctactata taccatgcgc
    32941 cagactgctg gcattagatt tgaggcagaa aaatgaaaac caaactaccg actgaatggc
    33001 aagaactgag tgaccaactc ggtttccaag aattcacccc cattcaaact caactatttg
    33061 agccccttct tgctggagaa aacctcctag gagtgagcca aaccggaact ggtaagaccc
    33121 tagcgtatct cctaccaagt cttctcagac tacaaaagaa aaaagcccaa caactcttga
    33181 ttctagcacc aaatacggaa cttgctggac agatttttga tgtatgtaaa acgtgggcag
    33241 aagctatcgg attgactgct caactcttcc tttcaggttc aagtcagaaa cgacaaattg
    33301 aacgtcttaa aaaggggcca gaaattctga ttggaactcc tggccgtatc tttgaactca
    33361 ttaaacttaa aaaaatcaag atgatgaatg tggaaaccat catcctggat gaatttgacc
    33421 aattactaga tgattctcag attcactttg tagaaaaaat cactcactac gcacctcgtg
    33481 accaccaact ggtctacatg agtgccacga ccaagtttga ccaagaaaag attgtgccga
    33541 atacacgcac tattgatctc tctgatcaaa aattggacaa tatccagcat ttctacatgc
    33601 aggtagacca acgtcatcga gtggatatgc tacgaaaact ggctcatgta gaggatttcc
    33661 gtggtctagt cttcttcaat agcctgtcag accttgggaa tgccgaggaa aaactacagt
    33721 atcgtgatat attggctgtt tccctcgcta gtgatgttaa tgttaaattt agaaaaatca
    33781 tcttagaaaa gtttaaagat aaccaactaa ccctgcttct tgcaactgac cttttggctc
    33841 gtggaattga tatcgatagc ctagaatgtg tcgtaaactt tgatattcct agagatagcg
    33901 aaacctacac acaccgtgct ggccgtactg gtcgtatggg caaggaaggt tatgttatca
    33961 ctctcgtcac tcatccagaa gaaatcaaaa aacttaaaaa gtttgcaagt atccgagaaa
    34021 ttgtcctaaa aaaccaagaa ctctatatca aataaagccc cattgctcta tacacatcca
    34081 gtgtatggag cttttttata agcaattcaa ttttatactc atctgctttc aaaaagcatt
    34141 ctattccatc tccgattaac gatggacttt atcacctcct tctccaatcc ttgtatgaca
    34201 tcttggagtt gattcatgac atcttccaaa gttcgaaagg ctttattctt aaatccacgt
    34261 ttacgaatct ctttccacac ttgttcaatg gggttcatct ctggtgtgta tggaggaata
    34321 aaggtaaaat caatattagt cggaatattt aaggtacttg atttatgcca tatagcattg
    34381 tccataacga gtaaaaggat aagcttgtga aagctcttct aaaaaggcgt tcatccactc
    34441 agtattacat ccaccagcta ttaagaaaaa tgattcgcct gtatggggca tcaacagctc
    34501 cataacaata gcgaaattct cgtatatagt gactatggac atgtggacct actcctattg
    34561 gagaccaaca agatcccagt ttactgattc taccgaaacc agcctcatct tggtacatca
    34621 agcgaacctt atgaaaacgt ctactatatt taaaacgctt tcttgccttc ttggattgag
    34681 attttatttt tagacgcgac aatggtttga gcgtctgctt tcttaggatg ttctggacgt
    34741 ggcataatat tcgccaacca tggcgcttca acagttgata gaaggcatca cgtgtgtagg
    34801 aacgatataa gcctgaaata aggtattgta acaaattctc ctgcctctgt agccttcaaa
    34861 tggcgggcaa gaaaggcttt ctcttcctaa actgtcatat atgcatggtt acgaccacca
    34921 cgtgtttctt gaaggagaga gtcgagtccg aactcctcat atttttttac atttcgccaa
    34981 atcgttgttt gattacagtc taaaagctct ataatctctc tttataagat ttgcccatca
    35041 gacgaaatag aacgatttga aggcgtttat gatatttagc tgtacgagag tcttttaaaa
    35101 gtgttttgat ggtttggatt tcttctttag ttgatttcat attactattg tataatgctt
    35161 tttgatttta gtctagtatt atactcttcg aaaatctctt caaaccgcgt cagcttcgcc
    35221 ttgtcgtata gatgttactg acttcgtcag ttctatctac aacctaaaaa cagtgttttg
    35281 agcagtctgc agctaacttt ctataacaaa atgaaataag aacaagacaa atcaatcaag
    35341 acaatcaaat cgatttctaa caatgtttta gaagtagatg tgtactattc tagtttcaat
    35401 atattatagt ttgctctttg attttcattg agtattagtt caatatctaa aaaaagaacc
    35461 ttgccaagca agattctttt agtgtctgac ttaaataatt gttcttctgg gaactaaatc
    35521 gaattaagct tcgatttctg taaccatacc tgaaccaaca gtacgtccac cctcacggat
    35581 agagaatgta gtaccttgtt ctacggcgat tgggtgaatc aactcaacgt cgattgtcac
    35641 gttatcacca ggcattacca tttcagtacc tgctggaagt tcgattgaac ctgtaacgtc
    35701 agtagtacgg aagtagaatt gtggacggta gttgttgaag aatggagtgt gacgtccacc
    35761 ttcttcttta gtaaggatgt agacttcacc tttgaattta gtgtgtgggt tgattgaacc
    35821 tggtttagcg ataacttgtc cacgttcgat ttcatcacgt tgaacaccac gaagaaggac
    35881 acctacgtta tctccagcaa gaccttcgtc aagttgttta cggaacattt caacaccagt
    35941 aacaactgct ttttgagttt cttctttgat accaacgatt tcgatttcgt cgttgacttt
    36001 aacgatacca cggtcgatac gtcctgaagc aactgtacca cgtccagtga ttgagaatac
    36061 gtcctcgact ggaagaagca atggtttgtc agtgtcacgt tctggttctg ggatatactc
    36121 atcaactgtg ttcatcaatt ccataacgat gtcttcgtat ttagagtcac cttcaagagc
    36181 tttaagtgct gaaccttgga taactggaag atcgtcacct gggaagtcgt attctgacaa
    36241 taggtcacgg atttccattt caaccaattc aagcaattct tcgtcgtcaa ccaagtcaac
    36301 tttgttcatg aagacgataa ggtgtttaac accaacctga cgtgaaagaa ggatgtgctc
    36361 acgagtttgt ggcattggtc cgtcagttga agctactaca aggatagctc cgtccatttg
    36421 agcagcacca gtgatcatgt ttttaacgta gtccgcgtgt cctggagcgt cgatgtgagc
    36481 gtagtgacgt ttttcagttt cgtactcaac gtgcgcagtg ttaatagtga taccgcgttc
    36541 gcgttcttct ggagcagcat cgatagacgc atagtcttta ggttggttaa ctgatgaagg
    36601 caagcgacgt gccaaaacag ttgtgatagc tgcagttagg gtagttttac cgtggtcaac
    36661 gtgtccgata gtaccaatgt taacgtgtgg tttactacga tcgtattttt cttttgccat
    36721 ttgagtaaaa gcctccaata aaatatattt tatagataga cagtaggcaa tacagtctaa
    36781 ctttccttac cattttatca aatttcagct aaattgcaag tgttttacaa cgtttttgtg
    36841 aattattctt ggtaaaaatt taactaacta atagaaagta ctaaatagac ttatccttca
    36901 aggagttttc agcattatcc atccactcac ttgctgaaaa tgtaaacagt ctctggttta
    36961 tatagtaaaa tgaaacaaga atagggcaaa tcgatcagga cagtcaaatc gatttctaac
    37021 aatgttttag aagttgaggt gtactattct agtttcaatc tactatacaa cctcaaaact
    37081 gtgttttgaa caacctgcgg ctagcttctt agtttgccct ttgattttca ttgagtataa
    37141 aattgcagat aaaacgataa caatcatagg actcagcaga gtcaatgtag gtcgaagaat
    37201 agccccccta atcgcttatt ttatagcaaa atgaaataga aactgaacat tttgttgagg
    37261 aaggtaaatc aattcctcac aatgtttgag aaagaaggga ggactattcc aacttcaacc
    37321 cactataaag cagacttaca agatagggaa cccatctccg ataatattcc gataatatat
    37381 agtagaatga aaactgcaca atttgattgg agaattcaaa ccaatttcta acaatgtttt
    37441 agaaacaagg gtctattatt tcaactgcaa cctactatag cccattgaag ctggaatagc
    37501 ccactgagac ttctaaacca ctgctggaga ggagtttgtt tagagtttgt ttagagtttc
    37561 tttcatttcc ctaaaaaatc aaaaagagag aaccagtctg atcctctctt acttatagat
    37621 ggtgctcact caaatgttaa aggagctatt tcttagagat aaaggaattt gaatacagct
    37681 actgccgcaa ttgctgctgc gataggtgct actactggta cccaagaata ccaccatttt
    37741 gaatcgcctt tatgctcacc aagaactgat tttggaagga aagcatgaag gagacgtggt
    37801 cccaagtcac gggctgggtt caaggcaggt cctgtaggtc ctccaagtga tgttaccaaa
    37861 gccataacga ggaatccaag tgccaagtga gccacagaaa gtcctgaagc agtgtgtgga
    37921 gccacctgtg ctttaatagc caagtcagaa aaatcaactg tttgtcctgc ttctattgcc
    37981 ttttgtttca tgaattgaag cacttcagca ccaaagaagt ttttagtcaa accaagagct
    38041 gcaaagaaca aaacaaatga accaacaaac tcattaatca aaccattgac agttgctgca
    38101 tagcgacttt cttttgtacc atggtcaata cttgaaatag ttgagaaagt tcctaagatg
    38161 ttatttggtt tttcagtttt caagtagaat ggacggtatg ttgccacaac taaggcttgg
    38221 ccaaagatag cccccaagac ttgcgcgata atgtaaggta ccacttgtgc ccaagggaaa
    38281 agaccgctaa ctgcaagccc tagagtgaaa gcagggttga tgtgattccc agatacgtta
    38341 ccaaacatca aggctgggat cataaccccc ataccataac caacagcgat gacgatccag
    38401 ccactttggt gacctttcgt acctttaagt tcaacgttgg caactgcacc attcccaaga
    38461 atgatcaaaa tggcagttcc caaaaattca gtggcatact tcagtgccca tgtgaaatcc
    38521 atttgctaga ttctccttaa aattttttag atattcctta ttttatcaat ttttacccta
    38581 tttagcaact gatttctgga aatattttta aaaaaatagg attcatagtt tcccagttca
    38641 acgtacttgt aagcgttttt atccttcaca aaagacctca ttctcaaaac caggaaaaag
    38701 cccacatctg tgatcttttc cttgttccta gattctaaaa tctattattt ttcatcttct
    38761 tttttcttga agaatcctaa tcctagacca gctaacaagg tcatgatacc agcactagcc
    38821 aaggtagcat tagcttctgt acctgtgttt ggcaattcct ctctcttacc tgtctcataa
    38881 gtcggaactt ctgggtctgg attcactgga gtttcagttt ttggagtacc tggttctgga
    38941 gttggtttat ctggtgttga taaacggtca taccttaccg ttatttcttt atcactagag
    39001 tctgacgtaa cttcttgtga ttcaactgtt ggaatatctg gatctttgta cttgtcaatc
    39061 ttaccagata taacctcgtc ccagtttcct gttgtccatt caccgtaggt tacaactccc
    39121 gtgaccttgt ctcagttttt gtacggctta aggttacagg ttgaacaaca tcttctttta
    39181 cattttggtt cgtaacttta tcaacgtaat gaatgatacg cgttatagtc ttcgtctcag
    39241 tagaggttgc tgttttggga accactgttt cctcaacatt ctcacggtag taatagtcaa
    39301 ctgttgcacc gtcttctggt acgcatttgc aggagttgct accaaggtgt atgttgtttt
    39361 ccttgtgata actcggtctt ctttgtcctc agttgttgtt ttcccttcaa tagtttttga
    39421 ttctgtggta tactcagaac ctatcgctaa atcagctttt ataacagact ctgccaactt
    39481 ctcttggcta ccttctttat agtaattggc tgttactgta gcagtggttg gcgcttcgct
    39541 ttctctataa actaaggtca ctgttctacc ttcgcttaca atattcccag ttaaacttgc
    39601 agaatttgta tctgcttctt taaaagtata atattttccg tcagtagtag tcatgctact
    39661 gagtttttta tctgtgacat tgtagctggt accaatcagt tgttttttat tggtaatgta
    39721 ggttccgtca ctttcttttt ctccaattcc agtatcattt ttcaatgata gcaaacgccc
    39781 ttgttcatca acatagcgaa ctttcacatt ttctgagatt agttctgcca attctgaggt
    39841 ttttttcttt ttcttgattt cttcggttat tttccctttc tcttcttcgg gaatatttag
    39901 ttttggaatg attttttcaa caacggttcg tgatggttcc acagtatctt ggatgactga
    39961 aaagtcagct agaattggga gattatactg aacacggtaa ctttgagtgt ttactcctac
    40021 tctttcatta ttctctgaaa atacttgtac ggtataagaa acaacatctt ttcctaatag
    40081 aacatcccca gtagagaaat agccgccttt tcctagtttg ctatctccag agcccacttc
    40141 tttcctaatc ttatcagata gttttttacc agtcagtaca ttcgttcgca caatcccttt
    40201 gtctacccct acaaagtggg agaacttttt gaactcttca gaaccagatc tagcccaacc
    40261 attattaagg gcatttgctt ttgtatttgt attctctctc aaaagtttgg cgattagaat
    40321 tatattcatc ggcacttaga gttgctgcta tatctgactc ttgaatacca acttccttac
    40381 taccatttct agcggcagta tatgtgtatt tatctgtttc tacttctagc tgattatcct
    40441 taacatgata ggtaattttc tcctggtata agagtcttca gtagtttata tgctctgtca
    40501 tcatctttag ctttagaagc agctgagttt agccaagttg gggtattagg agtatcttta
    40561 tcagcctgtt tcaagacatt attcaagtca tttgctagcc tattggttgt cctcactgtg
    40621 aaagttttct tccagtctga accactttta ttagacttag atatgctcat gaaatcctgg
    40681 tcaacattca acacaatatc gccttgtttt ttagcatctt ccgttgcttc tgcttcaaat
    40741 tgatcatgga gtttttgttg ctctggtgta tagttttttt atttacacga tttaatgtac
    40801 tattttttat tttagtatta agaactccat taatacgatt tttaaactct gcttcaaaaa
    40861 atcccttaat ttgttggtgc gcaagttcaa cattcaaacc tttcttatac aagtcttcat
    40921 tctgatacaa gtcttcattc tgaacgattt cggctacacg gtgaatggtt tgattgtata
    40981 ccgtcttctc ttaaccagca gtatccttag ttttaatgac tactcgatag gttcctttag
    41041 aaccgttata gtcatctagt tttaaaaaag cattccaaac attcaaaaat agttggaact
    41101 tcccttaata aatccgtcac tttctttttc aagatagccc aagcttgctc aataggattc
    41161 aaatccggtg aataaggtgg tagaggtaag aaaaagtgtt tatcttggat gcagagttca
    41221 tccaaaatgt tcttgggatg aaaactagca ttgcccatga caataacatg aggtgtcttc
    41281 aaagcaggta ggagttgcgt tttgaaccac tccacaaaga aatcgcttgt catgcttttc
    41341 ttgtaaatca tgggagctat aaactctccg tctacttgtc ctgcaacaat tgaagttcgc
    41401 tcaaaacgac gtccgctaat cttttcatag actttctccc ctctaggagc ccctgcataa
    41461 ggacgataga ggtagcggtc gattcctgtt tcgtcaatat atacgattgg taaatctttt
    41521 aggttatcca aaatatcaag aaactcagcg actttctctg gctcttgttc cttaaagctc
    41581 gtcatctttt tttaaagtga ccttaatctg ctttaaagct gcccatactg aaggaacagc
    41641 acaatcaaaa tgtgccgcaa tttcccgtaa aaaagcatct ggatgagcct ctacaaaggt
    41701 tttcaattcc tctaaaggaa tctttcggtt tttgacgact cgctttttcc tctctatgtg
    41761 ttcttgttca cgtctttctt ttcccacgtg aagagagttc tgacgccaac accaaaaaac
    41821 ttggctgcct cgacatggct gtgcccctct ttgatggaat ctaatgctcg ctgtttaaaa
    41881 tcagtactat atgccatagc tttattataa tatgcttgtt taaaactaag taactatatc
    41941 aatgttttgt tatgagaaga cttacttttt ttactgaaat tgaatttttc ctagcctcaa
    42001 catcatataa ccccaaaatt caatctgacc tggtttgaag agatgttcga agcagataag
    42061 gttttactaa aactaaaaaa aatgatataa tcaaactgat taaatgtttt aaaaataaag
    42121 gagaatttga atgtcttacc aagaaaatta ccagaaatgg gttgattttg tggagcttcc
    42181 tgactacctt cgtcaagatt tggaaaatat ggacgaaaaa actaaggaag atgccttcta
    42241 tacaaatctt gaatttggta ctgcaggtat gcgtggcttg gttggtgctg gtacaaaccg
    42301 tatcaacatc tacgttgttc gccaagctac tgaaggattg gctcgtttga ttgagtcaaa
    42361 aggtggaaac gagaaagaac gcggtgtagc aattgcctac gatagccgtc acttctcacc
    42421 tgagtttgcc tttgaatctg cggcagttct tgctaaacac ggcatcaaat cttacgtatt
    42481 tgaaagcctt cgtccaactc cagaactatc atttgcagtt cgtcatctca actgtttcgc
    42541 aggtatcatg gtcacagcca gccacaaccc tgctccattt aacggttaca aggtttacgg
    42601 tgaagacggt ggacaaatgc ctccacacga tgcggacgct ttgactactt atatccgtgc
    42661 aatcgaaaac ccatttgcag ttgaagttgc tgatgtggaa actgaaaaag cttctggctt
    42721 gattgaagtt atcggcgaag ctgttgacat agaatacctt aaagaggtta aggacataaa
    42781 catcaaccca gccttgattg aagaatttgg taaagacatg aagattgtct acacaccact
    42841 tcatggtact ggtgaaatgt tggctcgtcg tgctcttgcc caagcaggat ttgactctgt
    42901 tcaagttgtt gaagcgcaag caactgctga cccagacttt tcaactgtaa catctccaaa
    42961 cccagaaagc caagcagcct ttgcccttgc tgaagaactt ggtcgtcaag ttggtgcaga
    43021 tgttcttgtc gcaactgacc cagacgctga ccgtgttggt gttgaagttc ttcaaaaaga
    43081 tggtagctac ctcaaccttt caggtaacca aatcggtgct atcatggcta aatacatctt
    43141 ggaagctcac aaaaacgctg gaactcttcc tgaaaatgcc gctctctgca aatctatcgt
    43201 ttcaactgac ttggtaacga agattgctga aagctacggc gcaactatgt tcaacgtctt
    43261 gacaggtttc aaatttatcg ctgaaaaaat ccaagaattc gaagaaaaac acaaccacac
    43321 ttacatgatg ggatttgaag aaagcttcgg ttacttgatt aaaccatttg tacgtgataa
    43381 agatgccatc caagccgttc ttgtcgttgc tgaacttgct gcctactacc gttctcgtgg
    43441 tttgacactt gctgacggta tcgaagaaat ctataaagaa tatggctact acgcagaaaa
    43501 aacaatctct gttactcttt caggtgtcga tggtgctgaa caaatcaaag cgattatggc
    43561 taaattccgc aacaatgctc caacagaatg gaacgcaaca gctatcactg tcgtagaaga
    43621 cttcaaggca caaactgcta ctgttgctga cggtactgtt acaaacttga caactcctcc
    43681 aagtgatgtg ttgaaataca cacttgctga cggttcatgg attgccgttc gcccttcagg
    43741 tacagaacca aaaatcaagt tctacattgc agttgtaggg gaaaccaacg aagaatcaca
    43801 agctaagatt gctaacatcg aagcagaaat caatgcattt gtaaaataaa gacctataaa
    43861 agatgagacc aaccaacctc atcttttttc gtatcaaatc taagcaattt tagaaacttt
    43921 atggcatact agacttatca atgaaagcga ggtaatctca tggaacaatt tttagataac
    43981 atcaaagacc ttgaagtcac tacagttgtg cgtgcgcaag aagctcttga taaaaaagaa
    44041 actgcaacct tctttatcgg tcgcaaaact tgcccttact gccgtaaatt tgcaggtaca
    44101 ttgtcaggtg tcgtagctga aaccaaagct cacatttact tcatcaatag tgaagaacca
    44161 agccaactca atgatttgca agcattccgc tcacgctatg gaatcccaac tgtaccaggt
    44221 tttattcata ttacagatgg acaaatcaac gtccgttgcg actcttcaat gtcagcacaa
    44281 gaaatcaaag atttcgcagg attgtaaaaa atcagctaac aagtcttaaa atcacaaaaa
    44341 cgcataatgt aaggtgcaaa aaccttgata ttatgcgttt tattgttcct aaaacagtta
    44401 catcagcatt tcattacaga acattttaat tttggaagtc aaatcaattt ttaacaatgt
    44461 tttagaaatc acagtgggct attccatatt caattatcca gattcaatcg ctattatcgt
    44521 tttcctagat tacaaaaaaa actacgtttt gctaatcaaa acgtagtctc agccactatt
    44581 ttatcttact gtccttcttt tacttctttg gttgctacat cttctccaaa ccatttttgg
    44641 ctgatttctt ggaacttgcc gtccttgtaa agactagaaa aagcttcatt tatcttctta
    44701 accaaggttg tatcttcctt acgggctcca accgcaaaag cttctgtttc tagtccaact
    44761 gtaaagacat tataatcgtt taaaacacct tctgcttcta aataatagtt tgcatagaca
    44821 cggtcaatca atagaccatc aattcgatcg tttttcaaat caatcaaggc ttcattaaag
    44881 gtttggtatt gattcgcttc cttattagcg acaatattct tcaaaagttc tggatttgct
    44941 tcaaagtccg cataaccaga tgaaccagct tgagctccta atgtctttcc agtcatatcc
    45001 tttgcagtcg tgataccaga tgatttcttc gtaaccaata cctgctcatt cttcatatat
    45061 gagttactga aagccacctt ttcacggcgt tcgtctgtag cggaatagcc attccaaatc
    45121 agatcaatcg ttccttttgt caattcagct tctttcaaat cccaatcaat cggttgccaa
    45181 tttaccgtga ttccgtattt ttcaaaaaca gctgtagcta aatcaatatc aaatcctgca
    45241 taagaaccat ctttctgagc aaatcccatt ggaacaaaag tactatcaaa tccaatagta
    45301 atagacttgt tagactggta ctttgaccaa ttatctccac tagtttcgct agaatttttc
    45361 ccacaagcta ctaagaacaa agcagtcatc agactgacta atacaagcat ccattttttc
    45421 atccattttt cctcctattt aggttctact ttcaataata catctgcgat attttcagca
    45481 aactgcaaat catgggtaac cacaatctgg gtcatcccaa gttccctatt ttgcaagatt
    45541 agcttctcca cttccaaacg taattctgga tccagggcag aagttggttc atcgtagcca
    45601 atgatttctg ggtcaatcat catagcacgc gccaaagcca ctcgctgctt ttgcccacca
    45661 gatagtgaga aaggataggc ctctgcgtgt cctcctagtc ctaactgttc caagagtcca
    45721 ctcgccttct tctcagcctc ttcctgcttc attcccatgg tcttcacagg cgataaagtc
    45781 aaattttcca gaactgatag atgaggaaat agttgaaaat cttggaagac aaatcccagt
    45841 aggttgcgct tctgcaattc atccagctct aaaggttgtc cattataaaa gatttgccct
    45901 gaatcaatgg tttcaagacc tgcaagcata cgtaaaagag ttgtcttacc tccaccagaa
    45961 ggtccaacga tagccaggat ttgcttttca ggaatactta gactgaaatt agacaggatt
    46021 tgtttgtctc caaagacttt attgatattt cgtaattcta acatggcagc ctcctatcta
    46081 taataactat acttcttctc aacttttttg gaaataattg tcacaatccc aatcaaaatc
    46141 aaataaatgg ctcctgccaa gaacatagga accagactag catcgcggtt agcagctgtt
    46201 cgactagcca agataaggtc tgaaattccg agagcataga ccaaagaagt atccttgacc
    46261 aaactcataa cttcattaaa gacactagga agaacgatct tggtcacttg gggcaagata
    46321 atatagcgca ctctgtcaaa agggctaaac ttcaagacct tggcagcctc atactgtcct
    46381 cttggaatag tgtcaattcc cccacggaaa atttctgcaa agtaagccgc ataattcaaa
    46441 acaaaggcaa taatagctgc aggaaggcgg tctaaacgaa tcccaatact tgggagcaca
    46501 taatagataa aaatcagttg caagagtaag ggggttcctc gcataaccca gatgtaaatg
    46561 ttaatcagat aatggagggg cttccaatgg acttgcaagg caaaggcaat caaaacgccc
    46621 aagggaatcg aaaatagcaa gaccagtgca aagacctgta cagtcgtgct cgcaccattc
    46681 agtaaactcg gtaatatctc aaataaataa gacatactgc acctcctaaa agtaattgtt
    46741 cctattatag catgaataaa caagattacc aagtattttt gtaaaaagat tctaccatat
    46801 acaaataaaa accgtagcta tcaaaagaga taaactacag ttctatatgt ttaaacattc
    46861 ttacaatctc tcaaacagtt cttgcatttg cacatcatct ggaaccagtt ttaagtaagt
    46921 gtgagcatgg acttttgctt cttcaaaatg tcccaattca cgcaagagat agatatagtg
    46981 ttccagaaat tctggattgt ccttcaaatc tcctgtcaac tcttgataat gctcataagc
    47041 agtatccaaa tcgtccattt cttgataaga acgagcaatc atccacttgg tcaaaagatt
    47101 ttctggctcc tcactctgca agtctagaat atcctcataa cgctcctgct ccagataaat
    47161 agtggctaaa cgaagcaaga tttcttctgt atcctcagcg tcttcttttg cagtaaggag
    47221 ataattttct gcaccactag catcatgcaa ttcataagaa aattgtgaag cagctagcaa
    47281 gaggcgagtt tcaaagggat ttttctctaa tccttgctta gcgatacgca gggcttcttg
    47341 aacttgatgt tccttatgta aagcctgact gtacccatac tcatagcctt caaagtcagg
    47401 agaaatggta tcaagctgct taaagtagag ggtggctttt tgatattctt cttgatcaaa
    47461 ataaagactg gccaactcaa aagctgttaa gtcatcgtat tctaactcca gggctttttc
    47521 taaaaactca gtagccgttt caaatttccc taactgagca taggcaaagc caattcgttg
    47581 ataggtggaa atgcccgttt gctcataaat cgagcgatta tctaactggg cataggcttg
    47641 aatagccgct tggtaatttt ccaactcact atccaactct gccaaaccca atatcaagag
    47701 agaatcctct gagtaggtca aggcctccaa taatttctca cgtgccacat ctgtcaaacc
    47761 ttccagctgg taaaggtctg ccttcagagc caaagacgag acataccagt cactgtcagc
    47821 ttggatttcc tcaagatagg taaaggcttc ttctatttga ccatcctcgc tagcaattgc
    47881 agctagatta agatgaacct ctggaaaatc ctctacaatt ttcaggtaaa tttccttggc
    47941 ctgaggatag aaaccaatcc cttcaagata agttgccaac tcatacagaa gatcacttga
    48001 atcattttct aaagctttgg cgaaataatg ctcagcctta gttaaatctt gctcctccaa
    48061 agcctgtaac atctgttgac tattgttcac tcttgacttc ctcaccctct aattcatata
    48121 gaccactgac taccttatac cattcgaaaa tggctgaaat gacaacctta gcagaggcat
    48181 aaaccggaat accaagtaaa actccccaga taccaaacat agatcctgaa gttaacaaaa
    48241 caaagagaac attaatagga tggatgttta attgacttcc caaaatcaat ggagagacaa
    48301 aacggccttc aatagtttgt tctacaataa agacaatcac tactttcaaa agcatgactg
    48361 gaccagcaat caaacccaat actagggcag gaagcatggc tagaaagcta ccaagataag
    48421 ggaccagatt taaaatacca gcagtaaccc ccagcgtaac cgcatagcgt agaccaataa
    48481 tcttgaagaa gatgataaac attactgcta caataatagc cactgtcact tgccctcgaa
    48541 catagttgga caactgttga ttcacatctg atagaacttg tccaacaggt tccttcaatt
    48601 ttcttggaat gaattgggtc aaatagttac gcaagccttt cccatcacgc aagagataaa
    48661 agagcatgaa aggaacgata atcaaggcaa caatcacttg agaagctccg ctaataaagg
    48721 cactcaccca gttgactgcc tgagatgaaa ccttacttgc caaaactgta gcctggctag
    48781 aaaaattggt caaaacttgc tctaattgag gtctgaaatc atctggcagg tgctgggcta
    48841 ccaatccatt aacaatccta tctatatctt ctaagtaaac aggaacgttt cttgcaaagg
    48901 tcaaaacctg acgttgcaga tttggaatgg cgactgccaa gccccaaatg ataaagagag
    48961 cgataataac aaagacaata gtgatagcta taacacgatt aaccttatgc ttctccatcc
    49021 aatcaacaat aggattcaac aaataatata acaaaccaga caaaatgact ggcaacatca
    49081 caactgctat aaagtctaaa acaggtgaaa atagaaaact aatcttactt aaaataaaaa
    49141 gattcaatcc caataataag gttactaaaa ataccgtaat tgccttgtta tctaaaaacc
    49201 acttgaaaaa ccaagatagg ctaaaatgtt tctctttttg ctccataaat acttcctttc
    49261 tattgttctc tcattatacc atttttgaaa caaaataact cttttttaaa gtgcttacat
    49321 ctaattgaat gtctttaatt tgcttgtttt tgtgatataa tagtcttatc tttacacaga
    49381 ggtatagtaa tgaaagaaac tgtttatttt ggaacttata cacgtcgtac ttctcaaggg
    49441 atttacaagg cagactttga tacagaaact ggtcagcttt caaatctaga actttttgca
    49501 gctgagccaa gtccaaccta ccttgccttt gaccagcacc aacatttata cactgttggt
    49561 agccaagacg ataagggggg aattgcagcc tatcaaactg acgggactgt gttaaatcat
    49621 gttgttgaag aaggagctcc ccactgttat gttgctgtcg atgaaaagcg tgatttggtt
    49681 tacgcagcca actatcacaa gggacaagtc cttgtttata aacgccagga agatggtagt
    49741 cttctactta gtgatatgga tcaacacagt ggccaaggtc cacatgaaaa tcaagcttcc
    49801 ccccatgttc actatacaga tttaacacct gaccactatc tagtgacctg cgacttggga
    49861 actgaccaag tcatcaccta tgacctcgat caagaaggaa aattatctaa gctctatacc
    49921 tatcacagca agccaggagc aggctcacgc catatcattt tccataacca ctataaaatc
    49981 gcttatctca tttgtgaact caatagtact atcgaagttt taatctacga tggcgttggc
    50041 gaatttgaac gtatgcaggt tatttcaact ttaccagaag cttacgaagg ctttaatgga
    50101 accgctgcta ttcatctctc taaagacggt aaatacctct acgcttctaa ccgtggccat
    50161 gattctatcg cagtatatac catccttgcg gacggtagct tagagttatt agaaatcgtt
    50221 ccaacgcatg gtcagactcc acgtgatttt gatttgacac ccgaccaaaa atttctcatt
    50281 gttgtccatc aagactctga caatgcaact gtctttaaac gtaattgtga caatggtcgt
    50341 ctagcagaac tctccaacga cttccatgtt cccgaagcag tctgcatccg ttttgctcct
    50401 taaaacacca taaaaaatga acttggt
//
LOCUS       DAVMAH010000007        49222 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVMAH010000007 DAVMAH010000000
VERSION     DAVMAH010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49222
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.007"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            241..447
                     /locus_tag="VYO94_000356"
     CDS             241..447
                     /locus_tag="VYO94_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759051.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
     gene            444..638
                     /locus_tag="VYO94_000357"
     CDS             444..638
                     /locus_tag="VYO94_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759052.1"
                     /translation="MKKGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            625..1509
                     /locus_tag="VYO94_000358"
     CDS             625..1509
                     /locus_tag="VYO94_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759053.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            1511..2248
                     /locus_tag="VYO94_000359"
     CDS             1511..2248
                     /locus_tag="VYO94_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1759054.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGDINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            2248..3345
                     /locus_tag="VYO94_000360"
     CDS             2248..3345
                     /locus_tag="VYO94_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1759055.1"
                     /translation="MLERLKSIHYMFWTSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMCEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     DSMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            3347..3946
                     /locus_tag="VYO94_000361"
     CDS             3347..3946
                     /locus_tag="VYO94_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1759056.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            4371..5381
                     /gene="ccpA"
                     /locus_tag="VYO94_000362"
     CDS             4371..5381
                     /gene="ccpA"
                     /locus_tag="VYO94_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV1759057.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLTKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            5445..5828
                     /locus_tag="VYO94_000363"
     CDS             5445..5828
                     /locus_tag="VYO94_000363"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759058.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHVFEVVDETNEVSSKHVFEVVDETNEVSSKHVFEVVDETDEVSSKHVFEVVDETDE
                     VSSKHVFEVVDETDEVSNHTYGKAT"
     gene            complement(5857..6819)
                     /locus_tag="VYO94_000364"
     CDS             complement(5857..6819)
                     /locus_tag="VYO94_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV1759059.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            6885..8273
                     /locus_tag="VYO94_000365"
     CDS             6885..8273
                     /locus_tag="VYO94_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1759060.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDMLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            complement(8308..8760)
                     /locus_tag="VYO94_000366"
     CDS             complement(8308..8760)
                     /locus_tag="VYO94_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV1759061.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            8922..9216
                     /locus_tag="VYO94_000367"
                     /pseudo
     CDS             8922..9216
                     /locus_tag="VYO94_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9372..10586
                     /locus_tag="VYO94_000368"
     CDS             9372..10586
                     /locus_tag="VYO94_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1759062.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            10731..10865
                     /gene="rpmH"
                     /locus_tag="VYO94_000369"
     CDS             10731..10865
                     /gene="rpmH"
                     /locus_tag="VYO94_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV1759063.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            11128..11793
                     /locus_tag="VYO94_000370"
     CDS             11128..11793
                     /locus_tag="VYO94_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV1759064.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKLENTPGGDKGGNTGSSD
                     ANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKDKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGVQAIAMVTVPKRPVAPNAA
                     PKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVVATSGFALLGRKTR
                     RRK"
     gene            12098..12871
                     /locus_tag="VYO94_000371"
     CDS             12098..12871
                     /locus_tag="VYO94_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV1759065.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTS
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            12871..13431
                     /gene="rnmV"
                     /locus_tag="VYO94_000372"
     CDS             12871..13431
                     /gene="rnmV"
                     /locus_tag="VYO94_000372"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV1759066.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVRHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            13503..14402
                     /locus_tag="VYO94_000373"
     CDS             13503..14402
                     /locus_tag="VYO94_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1759067.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            14671..16701
                     /locus_tag="VYO94_000374"
     CDS             14671..16701
                     /locus_tag="VYO94_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1759068.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDEVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            16703..17344
                     /locus_tag="VYO94_000375"
     CDS             16703..17344
                     /locus_tag="VYO94_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759069.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            17337..17645
                     /locus_tag="VYO94_000376"
     CDS             17337..17645
                     /locus_tag="VYO94_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759070.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            17776..18648
                     /gene="rsmA"
                     /locus_tag="VYO94_000377"
     CDS             17776..18648
                     /gene="rsmA"
                     /locus_tag="VYO94_000377"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV1759071.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            18650..19528
                     /gene="rsgA"
                     /locus_tag="VYO94_000378"
     CDS             18650..19528
                     /gene="rsgA"
                     /locus_tag="VYO94_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV1759072.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            19539..20195
                     /locus_tag="VYO94_000379"
     CDS             19539..20195
                     /locus_tag="VYO94_000379"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1759073.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            20158..20820
                     /locus_tag="VYO94_000380"
     CDS             20158..20820
                     /locus_tag="VYO94_000380"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV1759074.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            20822..22078
                     /locus_tag="VYO94_000381"
     CDS             20822..22078
                     /locus_tag="VYO94_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV1759075.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            22068..23009
                     /locus_tag="VYO94_000382"
     CDS             22068..23009
                     /locus_tag="VYO94_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV1759076.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLVY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            23275..24102
                     /gene="purR"
                     /locus_tag="VYO94_000383"
     CDS             23275..24102
                     /gene="purR"
                     /locus_tag="VYO94_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV1759077.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            24169..25419
                     /locus_tag="VYO94_000384"
     CDS             24169..25419
                     /locus_tag="VYO94_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV1759078.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGE
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            25545..26339
                     /gene="pflA"
                     /locus_tag="VYO94_000385"
     CDS             25545..26339
                     /gene="pflA"
                     /locus_tag="VYO94_000385"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV1759079.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(26414..27340)
                     /gene="yidC"
                     /locus_tag="VYO94_000386"
     CDS             complement(26414..27340)
                     /gene="yidC"
                     /locus_tag="VYO94_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1759080.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(27418..27696)
                     /locus_tag="VYO94_000387"
     CDS             complement(27418..27696)
                     /locus_tag="VYO94_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV1759081.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            27730..28470
                     /locus_tag="VYO94_000388"
     CDS             27730..28470
                     /locus_tag="VYO94_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV1759082.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            28526..29209
                     /locus_tag="VYO94_000389"
     CDS             28526..29209
                     /locus_tag="VYO94_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV1759083.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            29321..30313
                     /locus_tag="VYO94_000390"
     CDS             29321..30313
                     /locus_tag="VYO94_000390"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV1759084.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            30378..30917
                     /gene="rsmD"
                     /locus_tag="VYO94_000391"
     CDS             30378..30917
                     /gene="rsmD"
                     /locus_tag="VYO94_000391"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV1759085.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            30907..31395
                     /gene="coaD"
                     /locus_tag="VYO94_000392"
     CDS             30907..31395
                     /gene="coaD"
                     /locus_tag="VYO94_000392"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV1759086.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDMIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            31379..32416
                     /locus_tag="VYO94_000393"
     CDS             31379..32416
                     /locus_tag="VYO94_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV1759087.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHIIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGASVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            32474..32704
                     /locus_tag="VYO94_000394"
     CDS             32474..32704
                     /locus_tag="VYO94_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV1759088.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            32728..34011
                     /gene="murA"
                     /locus_tag="VYO94_000395"
     CDS             32728..34011
                     /gene="murA"
                     /locus_tag="VYO94_000395"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1759089.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GLILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            34004..34192
                     /locus_tag="VYO94_000396"
     CDS             34004..34192
                     /locus_tag="VYO94_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1759090.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            34231..35055
                     /gene="endA"
                     /locus_tag="VYO94_000397"
     CDS             34231..35055
                     /gene="endA"
                     /locus_tag="VYO94_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV1759091.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            35346..36677
                     /locus_tag="VYO94_000398"
     CDS             35346..36677
                     /locus_tag="VYO94_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV1759092.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(36875..36945)
                     /locus_tag="VYO94_000399"
     tRNA            complement(36875..36945)
                     /locus_tag="VYO94_000399"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(36911..36913),aa:Cys,seq:gca)
     gene            37361..40972
                     /gene="rpoB"
                     /locus_tag="VYO94_000400"
     CDS             37361..40972
                     /gene="rpoB"
                     /locus_tag="VYO94_000400"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1759093.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            41005..44682
                     /gene="rpoC"
                     /locus_tag="VYO94_000401"
     CDS             41005..44682
                     /gene="rpoC"
                     /locus_tag="VYO94_000401"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV1759094.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            44793..45206
                     /gene="ndk"
                     /locus_tag="VYO94_000402"
     CDS             44793..45206
                     /gene="ndk"
                     /locus_tag="VYO94_000402"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV1759095.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(46135..46767)
                     /locus_tag="VYO94_000403"
     CDS             complement(46135..46767)
                     /locus_tag="VYO94_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759096.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLTG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(46769..48784)
                     /locus_tag="VYO94_000404"
     CDS             complement(46769..48784)
                     /locus_tag="VYO94_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1759097.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWFIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            complement(48929..49099)
                     /locus_tag="VYO94_000405"
     CDS             complement(48929..49099)
                     /locus_tag="VYO94_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759098.1"
                     /translation="MKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
BASE COUNT        14410 a         9388 c        11241 g        14183 t
ORIGIN      
        1 gtgtttgtct gataaaaatt tctactcttt ttgattttaa ataagtatta gtttacatta
       61 tggtgtgaat tgggtttgat atctcttttg aggaagttgc cttagatttt tctgattgtg
      121 ttttattgta tagtgtatct tgcttgtttt gaacagaatt ttttatgaca tttgtcatat
      181 tttctagtga cagaagcttc tgcctcctct gattttaaaa gactataatt gtagtatgaa
      241 atgggggaag aagagatgag aaataaaatg attatcgcag taagtttagt agtagcagga
      301 gttatgacct atctcatgtt ttcgggattg gatgaggatt tctaccattt tccttggaag
      361 gtctttgctg gctttggaat catgtcttgg cttgttagag aaggtttgaa attagtcaga
      421 gatgtgaaaa aggagtttga ggaatgaaga aagggatcat ctatttcttt atcggcctgt
      481 cactcttggt atggttagtg gaaatgttta ctgattggtt tgatcaagcc ttgcttcgcc
      541 aatttattcg tggtgctttg gggtttggat ttatgatttt cgtcgttttc cttatgggaa
      601 tggagtggtt gaaaggagag tctcatgacg gtggttaaag ttgagaaatt gagtaagaaa
      661 ataaaagaca aggaaatttt gcggaatatc tcctttgaaa tcaacgatgg tgaatgtgtt
      721 gccttaattg gtccaaatgg tgccggaaag acaacactct tagattgttt gcttggagat
      781 aaactggtca caagcggtca agtatctatt caaggtttac cagtgacgag ttctaagtta
      841 gactatacta gggcttacct ccctcaagaa aatgtaatcg ttcagaaatt aaaagttaaa
      901 gagttgattg ctttctttca acgtatctat ccaaatcctt tgagcaatca ggaaattgat
      961 caactattgc agtttgtcaa gcaacaaaaa gaacagttgg cagaaaaatt atcaggcggt
     1021 caaaagcgtc tcttttcttt cgtcttgacc ttaattgggc gaccaaagat tgttttttta
     1081 gatgagccta ctgcgtccat ggatacctca actcgtcaac gtttttggga aattgtccag
     1141 gagttaaaag cgcaaggagt caccattctc tattcgtccc attatattga ggaagtggaa
     1201 cacactgcag accgcatttt gctcttaaat aagggagagt tgattcgaga tacgacgcct
     1261 ctagctatgc gtagcgagga aatagaaaag cactttatcc ttcctatagc ttacaaggaa
     1321 gtcgtagagc agtcaaattt ggttgaaaac tggaccctaa agcaagattc tttacaagta
     1381 gtcactcgag aagcagatgc tttctgggaa ctattagccc aagcaggatg taggatgcaa
     1441 gaaatcgaag ttaataatcg tagtttgttg aatacaatct ttgaagagac gcagaaggga
     1501 gataactaag atgaaacgat ggatagcact tagtaagata gaatttttat tgaccaaacg
     1561 acaattaatc tattatctat tgtcggtagg gatgccgacg gctttctatt tatttttttc
     1621 tggtatctat caggacacac caggtgaact cgcgaatttt atgcgtgatt acctcatctc
     1681 catgactgcc ttttccatga tgtcgacaac tatcctctca tttccagctg ttttacatac
     1741 cgataagatg aacaactggc agaaaacatt gcgtcatagc cctgtaaata tggtagaata
     1801 ttatctatca aagataacaa gtatgctggt tgattatttg gtctcaattc tggttgtttt
     1861 tacagttgga cattttgtaa gaggtgtaga catgcctcta gtaaaatggg ttggagctgc
     1921 gattttgctg attgtgggga gtattgcttt tgtagcactt ggcttgacct tgactctctt
     1981 accaactagt cagctgatgt ctgttgtggg caatcttctt tatctaggat tggctgtttt
     2041 aggcggactc tggatgccca tttctttatt tccagactgg atgcaagcag ttggtaagtg
     2101 tctcccgacc tatcaattga tggagttgct caagaccttc ttaaacgagg gtgacatcaa
     2161 tctatcagcc acagtttatt tacttgtttt ttcagcagtt ttatttggtt tgactattta
     2221 ccttcaaggt cataaggaga atgcttaatg cttgaaagac tgaaaagcat acactatatg
     2281 ttttggacca gtttgatttt tatgcttttt cccatcctac ctgtagtgat tggggagctt
     2341 cctgcttggc atttattggt tgatattcta tttgtagtga cgtatttggg tgttttaata
     2401 actaagaacc agcgcctatc ttggcttttc tgggggctca tgctggtcta tgtagctggg
     2461 aataccgcct ttgttgctgg gaattatatc tggtttttct ttttcctttc caatctctta
     2521 atttatcatt ttggcgtacg tagtttaaag tctttacatg tatggacatt tctccttgct
     2581 caagtccttg ttgtggggcg acttttgatt tttcagagaa tcgaagttga gtttctagtc
     2641 tatatgcttg taattcttac ttttgtcgat ttgatgactt tgggctcggt tcgaattcgc
     2701 cttgtcgagg atttgaaaga agctcaggtc aagcaaaata cccagataaa tctattgcta
     2761 gcagaaaatg agcgcaatcg tatcggtcag gatttgcatg atagtctggg acataccttt
     2821 gctatgctta gtgtcaagac agatctagcc ttgcagctat ttcaaatgca ggcttatcca
     2881 caagtggaaa aggaattaag agaaatacag caaattagca aagaatcaat gtgtgaagtt
     2941 cgaaccattg tggaaaatct taagtctaga actttgacat ccgaactaga gactgtgaaa
     3001 aagatgttag aaattgctgg aattgaggtg gaaacagata accaactaga tactgctagc
     3061 cttactcaag aattggattc aatggcttct atgattttgc ttgagttggt gaccaatatc
     3121 atcaaacatg ccaaagcgtc taaagcttac ttaaaattag aacggacaga gaaggaactc
     3181 attttaacag taagtgatga tggctgcggc tttgcttttc taaaaggaga tgagctccat
     3241 acagtccgag atcgtgtttt tccattttca ggagaagtaa gtgtaatcag tcagaaacat
     3301 ccaacggaag tgcaagttcg actaccttat aaggagagaa actaagatga aagtattagt
     3361 cgcagaagat caaagtatgt tgcgagatgc catgtgtcaa ttgctcacgc ttcaaccaga
     3421 tgtggagtct gtccttcaag ccaagaatgg gcaagaagca atccaactat tagaaaagga
     3481 gtctgtagat atcgccatcc ttgacgtaga aatgcctgtt aagacaggtc ttgaagtctt
     3541 ggagtggata cgatcagaaa ggcttgaaac aaaggtggtt gtggtgacga ccttcaagcg
     3601 tgctgggtat tttgaacgtg cggtcaaggc tggagtggat gcttatgtat taaaggaacg
     3661 aagcattgca gacctcatgc aaaccttgca caccgtcctc gaaggacgca aggagtattc
     3721 acctgaattg atggaagtgg tgatgacccg tcccaatccg ttgacagaac aagagattgc
     3781 tgtcttaaag ggaattgccc ggggcttatc taaccaagaa atcgcagatc agctttacct
     3841 ctcaaacgga actattcgaa actatgtcac caatattctt tcaaaactgg atgctggtaa
     3901 tcgaacagag gcagctaata tcgcaaaaga atctggttgg ttatgatgat ataatatttt
     3961 catgaagact atgtgctaaa attgacggta gtgaatggaa caatacctat agtagattga
     4021 aactagaata gtacacctct acttctaaaa cattgttaga aatcgatttg actgtcctga
     4081 tcgatttatc ctgttcttat ttcattttac tataacttta ggagggctta gtttcctcct
     4141 ttttgtttag tctaaggtgg tagcaaggag ctaaacctag gttttctatg aaattttttc
     4201 aatcaatctt caaaaaacac ttgaaagtgt ttacaattag tgatagaatg gaataagtag
     4261 aaatatgaaa acgaaatttt cacatcttca cttttgtaag tagatataga gcttcaatca
     4321 gtacctctac ttgtaaaaga atgtgtgaga tagaaaggac aggaaaagga atgaatgcag
     4381 atgatacagt aaccatttat gatgtcgctc gtgaagcagg tgtttccatg gcgacggtca
     4441 gccgtgtggt caatggcaat aaaaatgtaa aagagaatac ccgtaaaaaa gtgctagagg
     4501 taattgatcg tttggattat cgtccaaatg cagttgcgcg tggtcttgca agtaaaaaga
     4561 caaccactgt cggtgtcgtg attccaaata ttaccaatgg ttatttttcg agtttggcta
     4621 aggggattga tgatattgca gaaatgtaca agtacaatat tgtcctagct aatagcgatg
     4681 aagataacga gaaagaagtt tctgttgtca ataccctctt ttcaaagcag gtagatggca
     4741 ttatctatat gggttatcac ttgacagata aaattcgctc agaattttcg cgttcacgta
     4801 ctccgattgt tctcgcagga actgtcgatg ttgagcacca gttgccaagt gtcaatattg
     4861 actataagca agcaacaatt gatgcagtga gttaccttac taaagaaaat gagcgtattg
     4921 ctttcgttag cggtccgcta gtggatgaca tcaatggtaa ggttcgttta gttggctaca
     4981 aggaaacctt gaaaaaagca ggaatcgctt atagtgaggg tttggtattt gaatctaaat
     5041 atagctatga tgatggttac gccttagcag agcgtttgat ttcatcaaat gcaactgcag
     5101 cagttgtgac aggtgatgag ttggcagcag gagtcttgaa cggtttggct gataagggtg
     5161 tttctgtgcc agaagatttt gaaattatta ctagtgatga ttcacaaatc tcacgcttta
     5221 cccgtccaaa cttgacaacg attgcccaac ctctttatga ccttggtgcc attagtatgc
     5281 gtatgttgac caagattatg cataaggaag agttggaaga acgtgaagtt ctcttacctc
     5341 atggtttgac agaacgtagc tcaacacgaa aacgtaaata gaaaaaatca gggaatcgag
     5401 aagatttcct gattttgtgc tcttaaacaa gagatgttga cttaatgaat accatagagc
     5461 ggactaggcg gctggttaaa ggctgcgcaa cacactgttt tgaggttgta gatagaactg
     5521 acgaagtcag ctcaaagcac tgctttgagg ttgcagatag aactgacgaa gtcagctcaa
     5581 aacatgtttt tgaggttgta gatgaaacta acgaagtcag ctcaaaacat gtttttgagg
     5641 ttgtagatga aactaacgaa gtcagctcaa aacatgtttt tgaggttgta gatgaaactg
     5701 acgaagtcag ctcaaaacat gtttttgagg ttgtagatga aactgacgaa gtcagctcaa
     5761 aacatgtttt tgaggttgta gatgaaactg acgaagtcag taaccataca tacggtaagg
     5821 cgacgtgacg tggtttgcag agattttcga agagtattag ccttccatat agtctttcaa
     5881 agcctgtcct gttagtccgg cattgagggc gatgaggagt ttcaagcgag ctttttgggc
     5941 gttgagttct ttaacaaaga aaacgcctgc tttttgcaac tgtacgcccc caccctggta
     6001 ggcataaaca ggctcggcaa taccgttaaa gcatcgtgat accagagcga ctggaattcc
     6061 tttttgcaga aggctttcta atttttgagc cgtttctttg ggaatattac cagctccgaa
     6121 ggcttggata atcaaaccgt ccaagtgttc taaatccagc atatcaatca gctcatctgt
     6181 cataccagca taagccgaga tgatagggac taaaccttgt atgtgatcaa ggtcaaagcg
     6241 aacacgaggt tcagctgttt tgaagtagag gatttcctgt ttcatgatga gaccaagggg
     6301 gccatgtgtt ggagtctgga aggtgctgac attagtcgta tgtgttttgg tgacatactt
     6361 ggcagcgtgg atttcatcgt tcataacgac caaaactcct ttgtcagcag ccctgtcatc
     6421 gctggccact cgtaaagcac ttaggtaatt ataaacacca tcactaccga gttcattgga
     6481 gctacgcatg gctcctgtta gaacgatagg catatgggga acttccatgg tatcaaggaa
     6541 ataggctgtt tcctctaaag tatcggttcc gtgtgtgatc accactccat cgtagttatc
     6601 tgcttcctct ttaattttct ggtagaggac cagcatatgt ttgggtttga tatggggact
     6661 tggaaggtta aaaaagtcca aggcgtggac ttggattcct tcaagtgggt tggacacatg
     6721 gttcatggga ttatctgaac tcgtcacaac agcgccagaa gcatcggcct gcatggaaat
     6781 agttccaccc gtatgtaaaa caaggatttt cttaggcatg atttactcac tctttctgaa
     6841 atgtggtata atcattgtat cacaaaaggg gagattggga taggatggaa gtcaaagctg
     6901 ttttttttga tatcgatgga accttggtca acaatcgcaa gagtgttttg aaatccacta
     6961 aggatgcgat taagattgtc aaagaacaag gggtactagt tggcgtagcg acagggcgag
     7021 gacctttttt tgttaaggaa ttgatggacg atttggatct ggattttgcg gtaacctata
     7081 atggccagta tatctttagt aaagacagag tcttgttcac gagccctatt tccaagttac
     7141 atttgcgcca tctaattagc tatgctaaaa aagagggcac ggagattgcc ttagggacca
     7201 aggatgccat gttgggttct aaaatcatgt cctttggtct gggttctttt tcccaacgaa
     7261 ttagtcgctt cgttccctct gttttaactc ggacggtgag tcagtctttt aatcgcatgg
     7321 tcagcaaggt tgttccccaa aaggaagagg acctgcttca cctgatgaat caacctattt
     7381 accaagtttt gatgctgatg acaccagaag aatctgagaa ggcggcagct gattttgaag
     7441 acttgaaatt gacacgtagc aatccttttg catcggatgt catcaatcag ggaaattcta
     7501 aattagaagg cattcgccga gttgggaaag aatatggctt tgacctcaac caagtcatgg
     7561 cttttggtga ctcagataat gaccttgaaa tgctggctgg cgtcggtatg tcggtcgcta
     7621 tgggaaatgg tagtagcagt gtcaaggaag ctgccaagca cattaccact agcaatcaac
     7681 aagatgggat ccacaaggcc ttggaacatt ttggtgtttt gtcttcagaa aaagtttttg
     7741 tcagccgtga ctatcatttc aataaggtca agaccttcca ccacatgatg gatgaacgaa
     7801 cccaagaaga acctcgagct tgggatttag agggtgcaac ccatagggct ggttttaaaa
     7861 tagaagaatt ggtggagttt gttcgagcag ccagtccttc tgaagaagat tttggtcaag
     7921 ctgtatcgca acttcatcag gcccttgata aggcagcaga taaagtagcc aagaagacac
     7981 ctgctcagca agatttgata gggcaagtgg atgccttgat tgacatgctt tacttcacct
     8041 acggcagttt tgtcttgatg ggggtggacc cagaacgtat ttttgatatt gtccatcagg
     8101 ccaatatggg gaaaattttt ccagatggta aggctcattt tgatccagtg acccataaaa
     8161 tcttaaaacc agataattgg gaagaaaaat atgctccaga acctgctatt aaaaaggaac
     8221 tgcagcgcca gctcaaggct tacgaacgcc ataaagagag aaataaatcg taaacaaaaa
     8281 ggagctaggg gctccttttc tttgtgatta taaggttttt tcttgttctc ttacaaccag
     8341 caaatcgacc ttagcatggc ggagtatgta ttcagatgaa gagccgacca agaggcgttc
     8401 aaaggcgttg agaccagttg cgccaacgag gatgaggtcc acttcctcgg catctggaat
     8461 agtacgtgct agcagggtct ttggatttcc catttcaatg acgatatgaa catctgctac
     8521 cccagcatct ttagcacgtt tttcgtactc tttcatcaga ctttcagcgt cgacttggag
     8581 ttcttcgtaa acttcagcat caaaggtgga tacgctttgg agagcgcgtg tgtcaatgac
     8641 atgtgcgatg gtgagtttag cgtcgtttcg tagagcagaa tgaactccct tgacaaaagc
     8701 caagtccgct tccttagaac catcgattgc gaccatgata ttttggtaac gttgtgccat
     8761 aatgaaacct cctgaaattt tcttactata attgtaaacc ttttcactat agaagtaaag
     8821 caaaaaaagt atttttcaaa agaatattag ggcttaaact ctatataaat atatgataaa
     8881 ataaaagaaa ggatagcagg aaagaagtga aggaagggag aatgatgaaa aactcttttc
     8941 aaaaatcaaa tttcctttat tatggaatta tcctagtttc agtcttggta gaagtgatca
     9001 tgatctgtca attagagagt ctggtaccgc ttctttatcc aagttttatt ggatttttag
     9061 tttttcatgt actctaccat ctaatcttat ttctagttgc aaaacgaagt gggcgttggg
     9121 attacttgat gatatggggg cttttcctca tgtttaatct tctttatgac tcctttctag
     9181 gcttgctttt ttctaggttt atcttttggt atgtgatgtg tctttgcaaa atacctgcta
     9241 tctctacgtt cttaacctcg cctttagcaa ggtttttctt ctatacgaaa ctagtaacac
     9301 atttcagtaa acttgtcgca ttctctttct agtggtataa tgttactatc ctgatgaatt
     9361 gaggaaacaa gatgaaagaa tataacaagt ctagtaagtt agagcatgtt gcttatgata
     9421 tccgtggtcc tgtattggaa gaagccatgc ggatgcgagc gaatggagaa aagattttac
     9481 gtctgaatac aggaaatcca gcagaatttg gctttacagc gccagacgag gtcattcatg
     9541 acttgattat gaatgcgcgt gatagtgaag gctattctga ctccaaaggg attttctcag
     9601 cccgtaaggc catcatgcag tattgccagc tgaagaaatt cccaaacgta gatattgatg
     9661 atatttacct tggaaatggt gtcagtgagt tgattgtcat gtccatgcag gggcttttgg
     9721 acaatgggga tgaggtctta gtgccaatgc cagactatcc tctatggacg gcggctgtca
     9781 gcctagctgg aggaaatgcc gttcactata tctgtgatga agctgtggaa tggtacccag
     9841 atattgacga tatcaagtca aaaatcactt ccaataccaa ggcaattgtc cttatcaatc
     9901 caaataaccc aactggagcc ctttatccta aggaactctt gctggagatt attgagattg
     9961 cccgtcaaaa cgatttgatt atctttgcgg atgaaatcta tgaccgcatg gtaatggacg
    10021 gacatgtgca tacgcctgtg gcgagcttgg caccagatgt cttctgtgtc agcatgaatg
    10081 gtctgtcaaa atcccaccgc atagcaggtt tccgtgtggg ttggatggtc ttgtctggcc
    10141 ctaagactca tgttaagggc tatatcgaag ggctcaatat gctgtccaat atgcgccttt
    10201 gctctaacgt tttggcccaa caagtcgtac aaacttcctt ggggggtcac caatcagtcg
    10261 atgaattgct tcttcctggt ggacgaatct acgagcaaag aaatttcatc tataatgcca
    10321 ttcaagatat tccaggtttg tctgccgtta aacccaaggc ggggctctat atcttcccaa
    10381 aaatcgaccg caatatgtac cgtatcgatg atgatgagca gtttgtcctt gatttcttga
    10441 agcaggaaaa ggttctcttg gttcatggtc gaggctttaa ctggcaggaa ccagaccact
    10501 tccgtatcgt ttaccttcct cgtgttgatg agttagccca aatccaagaa aagatgactc
    10561 gtttcttgaa acagtatcgt agatagggct tgcattcgaa aaagctggaa acatttgcct
    10621 agagctattg acaaaagtga aagaatcaga tagaatagta aagtatgttt agtaactgat
    10681 cactttatag ccggctaaac gaatacaaaa tctatgagga ggtattcatc gtgaaacgta
    10741 cttatcaacc aagtaaactt cgtcgtgcgc gcaaacacgg attccgtaac cgtatgtcaa
    10801 ctaaaaatgg tcgtcgcgta ttggcagctc gtcgtcgtaa aggacgcaaa gttttggctg
    10861 cataatccaa acgaattcta tcaaaaatca gtaggaactc gagtctactg atttttattt
    10921 ttgtaaaaaa gttcagtaga tgcaaatgga ttcggaagcg atgttatagt agattgaaac
    10981 tagaatagta cacctctgtt tctaaaacat tgttagaaat cgatttgact gtcctgatcg
    11041 atttgtcctg ttattatttt attttactat aaagttgaag tagctggaga tggtacagca
    11101 acaatcacat tcccagatgg ttcagtagtg acgattctag gaaaagatac agttcaacaa
    11161 tctgcgaaag gtgaatctgt aactcaagaa gctacaccag agtataagct agaaaataca
    11221 ccaggtggag ataagggagg caatactgga agctcagatg ctaatgcgaa tgaaggcggt
    11281 ggtagccagg cgggtggatc agctcacaca ggttcacaaa actcagctca atcacaagct
    11341 tctaagcaat tagctactga aaaagaatca gctaaaaatg ccattgaaaa agcagccaag
    11401 gacaagcagg atgaaatcaa aggcgcaccg ctttctgata aagaaaaagc agaactttta
    11461 gcaagagtgg aagcagaaaa acaagcagct ctcaaagaga ttgaaaatgc gaaaactatg
    11521 gaagatgtga aggaagcaga aacgattgga gtgcaagcca ttgccatggt tacagttcct
    11581 aagagaccag tggctcctaa tgctgctcct aagacaacaa gtgcaccgca agcaactgca
    11641 ggaacaatgc aagatgttac ctaccagtca cctgctggca aacaattacc taacacaggt
    11701 tcagcatcaa gtgcagcact tgctagtctt ggtctagtgg tggcaacaag tggttttgct
    11761 ttgctaggaa gaaagactag acgtagaaaa tagaacagct agaaaattct attctctact
    11821 taaagttaga ttataagggg gattttgaga agtcatcaat cctagtgatg ggtgagaaaa
    11881 gtgagaaccc aagataatca catactttag ctgaatagga atattctatc aatgtagcca
    11941 atctcttctg tctctaactg tggaatagga gatgggcaat atcggataga aaagatagca
    12001 gaatagctct ctattgaaga gaggagggga aaccgaaaaa ttaggtgccc ctcctctttt
    12061 ttggtataat agaagataga aaacgaggtt agaagagatg atttttgata cacatacaca
    12121 cttgaatgta gaagaatttg caggtcgtga ggcagaagaa attgccttgg ctgctgagat
    12181 gggtgtgaca cagatgaata ttgttggttt tgataaaccg acgattgagc gtgccttgga
    12241 gttggtagat gagtatgatc agctctatgc gactattggt tggcatccta cagaagctgg
    12301 tacttataca gaggaagttg aggcttactt gttggataag ttaaaacatc ccaaggttgt
    12361 ggctttaggt gaaattggct tagattacca ttggatgaca tcgcccaaag aggtgcagga
    12421 gcaggttttt cgccgtcaga ttcagctatc taaggacttg gatttgcctt ttgttgtcca
    12481 tacccgtgat gcgctggaag atacctatga gattatcaag agtgagggcg ttggtcctcg
    12541 tggtggtatc atgcattcat tttcagggac gcttgagtgg gcagagaagt ttgtggatct
    12601 tggtatgacc atttccttct caggagtggt gacttttaag aaggcaactg acctccaaga
    12661 agcagctaaa gagttacctt tggacaagat tttggtggaa acagatgcgc cttacttagc
    12721 acctgtaccc aagcgtggtc gtgaaaataa aacagcctat actcgctatg tggtcgactt
    12781 tatcgctgac ttgcgtggta tgacgacaga agagctggcg gtagcaacga ctgcaaatgc
    12841 agaacgaatt tttggattgg acagcaagta atgaaagaga aaatttctca agttatcgtg
    12901 gttgaagggc gtgatgatac ggtcaatctc aaacgttatt tcgatgtgga gacctatgag
    12961 actcgaggtt ctgccatcaa tgctcaggat atagagcgga ttcagcgcct gcaccaacgt
    13021 catggagtca ttgtctttac agacccagat tttaatgggg agcggattcg gcgcatgatt
    13081 atgacggcca ttccaacagt tcggcatgcc tttctcaagc gagatgaagc tgttccaaag
    13141 tccaagacca aggggcgttc tctgggaatt gagcatgcca gctatgaaga cctgaaaacg
    13201 gctctagctc aggtgacaga acaatttgaa catgagagtc agtttgacat tagtcgtagc
    13261 gatttgattc gccttggttt tctagcaggg gcagacagcc gtaagcgtag agaatatctc
    13321 ggagagactc tccgaatcgg ctattccaac ggcaagcaac tcctcaaacg cctagagttg
    13381 tttggggtta ctttggcaga agtggaagaa gctatgaaat cttatgagta ggaaagatgt
    13441 agccgttaca attttttaag tttcacagta tttttcgaag caggtagaag aggaggcgtc
    13501 tgatgttaat tggtcaaaaa attaaagaga ttcggataga aaaaggaatt agtcgtccag
    13561 atttttgtgg agatgagcaa gaactgacag ttcgtcaact gtcgcgaatt gaaagtggag
    13621 cttcgcaacc gagtttgccc aagttagact atattgctcg ccggctagga gttccagttt
    13681 atagccttat gccggatttt tcagctcttc cttctgctta tttagaattg aaataccaga
    13741 ttttacgtga accaatctat ggtaaagaag aggagtacga taagaaggaa gcgtgtttgg
    13801 aagagattta taaaacatac tttgataatc ttcctaaaga agaacaatta gcatgtgaag
    13861 tattgcaggc gtgtttggat acttctagaa ctagaaggcc tgaatatgca gagttaatac
    13921 ttgaggaaca tatgcctcag attatagaaa aagaagctta ttcaataaat gatatgttgt
    13981 tgattcgttt gtttttttat caaatgctca ttagaaaaga tcttgccaaa tttataaatc
    14041 aaatcgaaaa gctaatgctc tttcttttgg aacagaagaa ggtaactcaa atagagaatt
    14101 actttataat tagagatact cttatttcag gaatgtgttg tcttgaaaag gtaggagtaa
    14161 ctgattgttt taatgattat ctatcgtgtt tacaagaaat tatggataaa actcaagatt
    14221 atcaaaagaa acctcttgta tttatgtttt tgtggaagca agcattaaga gtagaaagag
    14281 attttagttt agctgaatca ttttatcagt cttctaaaac atttgcgaag ctaattggag
    14341 atggatttct agtaaagaaa ttgacagagg aatggcaaga ggatgtcaaa aaatatttat
    14401 aaacatagtg aatcagtgac aaaaatgtcc ttgtcctcgt atcaaaacag ttctaaagtt
    14461 cgtctttaga actgtttttt tagatataag ctaaaaataa tatgaaatag ttagatttta
    14521 aggacattga tgtccttgat agttcttgaa aaaacggata taatatattt gaagatgttg
    14581 ctagcagaaa gaacttaata agcttcttaa catcgcagtg actgtggtca ccttctcact
    14641 aagtgaccaa gtaacttttt ggaggaaatg atgaaacgtt tatttatttt gatttcaatg
    14701 gtattggtat cgctttatat ggtgataact tccgttgacc atcgagaaga gattttattt
    14761 ggtaactatc cttctgttga tgtgacagga atgatgataa atcaaccagt agctagtcgc
    14821 gaagaggtga cagaggcttt gagtcacttg gcggtagagc ataatagtct catcgcccgt
    14881 cgaatcgttg agccaaatga agctggagaa acactcttta cctatgccac ttatggtgag
    14941 ggagagcttc cagaaggtct gaccatttcc tccaaggaga gtgcagaaac gagtgattta
    15001 ttagggtctt acttgattgt atcaggaagt ttggatgaag tgagcttaca gaccaccttg
    15061 aaagagcttg gttatcaagg ctttgtttcg aatggagaag atccattttc gatagtctta
    15121 ctattgacgg ccacccctat ggtgctactg agtttagcta tttttctgct gacctttatg
    15181 agtctgaccc tgatttatcg gatcaaatcc cttcgtcagg cagggattcg cttaatagct
    15241 ggtgagagct tgtttggagt tgctctcaga ccagtgttag aagatgtgag acagcttatc
    15301 tgctcagtgc tggtatccag tcttttggga ttggggattc tctggtatca aggtgccttg
    15361 tttatggcaa cggtgcaact ggtcatcatt gctcttctac tttatggatt gaccttggca
    15421 gggatttcta ccttactaag tgtcgtctat ctacttggtt tacaggaaaa tagtctggtg
    15481 gatctattga aagggaaact ccctctcaaa cgtatgatga cattgatgat ggtggggcaa
    15541 ctcttagctg tattggtggt cggatcgagt gcgacagctc tcctacccca ctaccgtgaa
    15601 atgcaggaaa tggagagagc tagcaataaa tggagccagt cctcagaccg ttaccgtcta
    15661 tcctttggtt ggtctagtgc atttgccgat gaagaaggaa cgcgtaagga taatcgtgag
    15721 tggcagacat ttactgaaga acggttagcc aatacagact ctttttatat tatgagcaat
    15781 gttgacaatt tctcagatgg agcagaagtg gacctagatg gcaatcgtct cagtgactac
    15841 acaccgtcag ggaatgttat ctatgtctca ccacgctatc tgatagaaga aaagattacc
    15901 gtttcttcag agtttatgga caagatgcaa aacttgtctg agggagagtt tgggctgatc
    15961 ttgcctgaga gcttgcgaga gcagtctgcc tactaccaag gattgtttac agattacctg
    16021 caaaactttt catctgaaag tgtagaagtg acgagtcaga aacactactt cccacaggta
    16081 aggctagctt ttacagaaac aggacaggaa cgtttcctct ataatgatgg gtacaagaca
    16141 acacgccagt acctaaaaga tccgattatt gtagttctaa cgccgcaagc gactggaaca
    16201 agacctgttg cagggatgtt gtggggaact acggctaata gtgccttgaa actagatcga
    16261 tatggagaca gcatcacagc tctaaaagag caaggtctgt atcacaaggt ttcttacttg
    16321 gtaaaaagcc agctattttt tgccaaggta ctaaatgaca aacgggtgga gttttactct
    16381 ctccttattg ggacgatttt gaccctgtct acggctatct tgttatttga ttccatgaat
    16441 cttctctatt ttgagcagtt cagacgggag cttatgatta aacgtcttgc tggtatgaca
    16501 atctatgagc ttcatggcaa gtatttactg gcgcaaggag gagttctctt gcttggccta
    16561 gtcctatcta gtattttgac aagagatggt ttgattagcg ctctagttgt agctttgttt
    16621 acgcttaacg ccctcttgat tttagtaagg caggacaaaa aagaagaagc tggtagtatg
    16681 gcagtattga aaggaaaata agatgattga tattcaagga ttggaaaaga aatttaatga
    16741 ccgcgcgatt ttctctggtt tgaatctcaa gctggagaag ggcaaggttt atgccttaat
    16801 cggaaagagt ggaagcggaa agacgacgct gctgaatatc ttgggaaagc tagaaaagat
    16861 agatggagga agggttctct atcaggggaa agatttaaaa accattccca ctcgtgagta
    16921 ttttcgagat cagatgggct atctctttca aaattttggc ctcttagaaa accaatcaat
    16981 caaagaaaat ttggatttgg gttttgttgg tcagaaaatc tcaaaagtag aacgtttgga
    17041 aaggcaagtg ggggctttag aaaaagttaa tctagggtat ttggatttag aacaaaaaat
    17101 ttatacttta tctgggggag aggcccaacg agttgccctt gctaagacta ttttgaaaaa
    17161 tccacccttg attttggcag atgaaccaac agcagctctt gatcctgaaa attcagagga
    17221 ggttatgaat ctcttggtgg atttgaaaga tgaaaatcga attatcatca ttgcgaccca
    17281 taatccccta gtctggaata aggctgatga aatcattgat atgaggaaac ttgctcatgt
    17341 gtgaaaaaat ccgtattcgc agggtatctg attatcctag tgccagaggt ggtttagaag
    17401 atatcctcat catggaaaat atgaccaatc atctcctttt ggttcaaatc cgagtgcatg
    17461 gctatttgct tgattttgct agtattgaag ggcaaaggca aaagcattat cgtttgaaaa
    17521 atttacctca gacggttgaa ctgacagtgg atgatgtgga ggaggatgtg gatttgaccc
    17581 tacctgaaaa tcgaagttat caagaagctg atttttttga acgcatgttt cgagagaact
    17641 gttaaggcca cttttaaaga tttccaagac tatctttctt catgaggaaa gatagttttt
    17701 tggtatgatt ttcattccca aaatacaagg ggaatgtgtt acaatagtag taacagataa
    17761 tagaaaagag aatagatgag aattgcagat tatagcgtga ccaaggcagt gctggagcgt
    17821 cacggtttta cctttaaaaa gtccttcggg caaaatttcc tgacggatac caatatcctt
    17881 caaaaaattg tggatacggc tgaaattgat gaccaggtca atgtcatcga aatcgggcca
    17941 ggtattggtg ccttgacgga gtttctggct gagcgtgcag cccaagtcat ggcttttgag
    18001 attgaccacc gtttggtgcc aattttggta gataccctgc gtgattttga taatgtgact
    18061 gtagttaacg aagatattct caaggttgat ttggcgcaac atatccaaaa ttttaaaaat
    18121 cctaacctgc caatcaaggt agtggctaat ttgccttact acatcacgac gcctattctc
    18181 atgcacttga ttgagagtgg cattcctttt tgtgagtttg tggtcatgat gcagaaagaa
    18241 gtagcggacc gcatttcagc ccagcctaac accaaggctt acggtagctt gtctatcgcc
    18301 gtgcagtatt acatgacagc caaggttgcc tttatcgtgc ctcgtacggt ctttgtgcca
    18361 gcgccaaatg tggattcagc catcttgaaa atggtgcgtc gtccagagcc agccgtagca
    18421 gtagaagatg agaacttttt ctttaaggtt tccaaggcta gttttaccca tcgccgcaag
    18481 accttgtgga ataacttgac aggttacttt ggtaagactg aagaggtcaa ggacaagctg
    18541 accaaggctt tggaccaggc aggcttgtca ccaagtgtgc gtggggaagc tctcagcttg
    18601 gcagaatttg ccggtctagc agacgcactt aaagggcaag gactctaaga tgcagggaca
    18661 aatcattaaa gccttggcag gtttctacta tgtggagagt gatggccagg tttatcaaac
    18721 acgcgcgcgt gggaatttcc gtaaaaaagg ccatacccct tatgttgggg actgggtaga
    18781 tttctctgcc gaggaaaatt cagaaggcta tatcctcaaa attcacgaac ggaaaaacag
    18841 tctggttcgt ccgcctattg tcaatatcga tcaagctgta gtaatcatgt ccgtcaagga
    18901 acctgatttt aacagcaatt tgctggatcg tttcttggtt cttttggagc acaagggcat
    18961 ccatcccatt gtctatattt ccaaaatgga tttgttggaa gataggggag aactggattt
    19021 ttaccagcag acctatggtg acatcggcta tgactttgtg accagtaaag aggaactcct
    19081 gtctttgtta acaggcaagg ttacggtctt tatggggcag acaggtgttg ggaagtcaac
    19141 tcttctcaat aaaatcgcac cagacctcaa tcttgaaacg ggagaaattt cagacagtct
    19201 aggtcgcggt cgccatacca ctcgagctgt tagtttttac aatctcaacg ggggtaaaat
    19261 cgcagataca ccaggatttt catccttgga ctatgaagta tcaagggctg aagacctcaa
    19321 tcaggctttc ccagagattg ctactgttag ccgagattgt aagttccgta cttgtaccca
    19381 tacccatgag ccgtcttgtg ccgtcaaacc agctgttgaa gagggtgtta ttgcaacctt
    19441 ccgttttgac aattacctgc aattccttag tgaaattgaa aatcgtagag aaacctataa
    19501 aaaagtcagc aaaaaaattc caaaataagg agaaacctat gtctcaatac aagattgctc
    19561 cgtcaattct ggcagcagat tatgccaact ttgaacgtga aatcaaacgt ctagaagcaa
    19621 ctggggcaga atatgcccat atcgatatca tggacagtca ttttgtaccg caaatcagtt
    19681 ttggtgcagg tgtggtcgag agccttcgtc ctcatagtaa gatggttttc gattgccact
    19741 tgatggtgtc aaaccctgag catcatctgg aagattttgc gcgtgcaggt gcagacatca
    19801 tcagtatcca tgtagaagca acacctcata ttcatggcgc cctccaaaaa attcgttcac
    19861 tcggagttaa gccttcagtc gttatcaatc ctggcacacc agttgaagcc atcaagcacg
    19921 tccttcatct agttgaccaa gttttagtca tgacggttaa tccaggtttt ggtgggcaag
    19981 cctttctgcc agaaaccatg gataaggttc gtgagttggt tgctcttcgt gaggaaaaag
    20041 gtttgaactt tgaaatcgaa gtggatggtg ggattgatga ccaaactatt gctcaagcca
    20101 aagaagctgg tgcgactgtt tttgtagcag gttcctatgt ctttaaggga gaagtcaatg
    20161 agcgagtaca aactctcaga aaacaactgg actagggttg cagtttttgc aggcggaaac
    20221 cgcggtcatt atcggacaga ttttgatgct tttgttgggg tggatcgagg ctcgctctgg
    20281 gtcttggaag aagacttacc tcttgctcta gcagtcggag attttgattc tgtgacggaa
    20341 gaagagcgac aggtgattca aaaacgtgcc cagtattttg tccaagcccg accagaaaag
    20401 gatgatacag atctggaatt ggctctctta accatctttg aacaaaatcc tcaggctcag
    20461 gtcactattt tcggtgcctt gggtggccgt attgaccata tgttggccaa tgtctttctg
    20521 cctagcaatc ctaagttggc accctatatg cgtcaaatag aaattgagga tgggcaaaat
    20581 ttgattgcct attgttcaga agggaccagt cagctagaac ctcgttcaga ctacgactat
    20641 ctagccttta tgccagttcg ggatagccag ctgactattc ttggagctaa gtatgagttg
    20701 acagaggaga attttttctt taaaaaagtg tacgcttcta acgaatatat agatagggaa
    20761 gtgtcggtaa cttgcccaga tggttatgtg gtcgtactgc atagcaagga caggaggtag
    20821 gatggaaagt ttacttattc tattattaat tgccaaccta gctggtctct ttctgatttg
    20881 gcaaaggcag gataggcagg agaaacactt aagtaagagc ttggaggatc aggcagatca
    20941 tttgtcagac cagttggatt accgctttga ccaagccaga caagccagcc agttagacca
    21001 aaaagatttg gaagtggctg tcagcgaccg tttgcaagaa gtgcggattg aattgcacca
    21061 aggcctgacc caagtccgtc aagaaatgac agataatctc ctccaaacta gagacaagac
    21121 agaccaacgt ctccaagcct tgcaggaatc aaatgagcaa cgtttggaac aaatgcgcca
    21181 gacggtcgag gaaaaactag aaaagacctt gcagacacgc ttacaggctt cctttgagac
    21241 agtttctaaa caactggagt ctgtcaatcg tggtcttgga gaaatgcaga cagttgcccg
    21301 tgatgtcgga gctcttaaca aggttctctc tggaaccaag acgcgaggga ttctgggaga
    21361 attgcaactg gggcaaatta ttgaagacat catgacacct gcccagtacg aacgagaata
    21421 cgcaacggtt gaaaactcta gtgaacgagt ggagtatgcc atcaagttac ccggacaagg
    21481 cgaccaagaa tacgtctatc tgccaattga ctctaagttt ccactggcag attattaccg
    21541 cttggaagaa gcctatgaga caggtgacaa ggatgagatt gaacgctgtc gtaagtcact
    21601 cctagcaagc gtcaagcgct ttgccaagga tatcaagagc aagtacatag caccgcctcg
    21661 gacaaccaat tttggaatct tgtttgttcc gacagaaggt ctttattcag agattgtgcg
    21721 caatccggtc ttctttgatg atttgagacg ggaagaacag attatcgttg caggaccaag
    21781 taccctatca gcccttctta actccctatc agttggtttc aagaccctta atatccaaaa
    21841 gagtgccgac catatcagca agactcttgc cagtgtcaag accgagtttg gcaagtttgg
    21901 tggtattctg gtcaaggcac aaaaacatct ccaacatgcc tctggcaata ttgatgaatt
    21961 attaaaccgt cgtaccatag ctatcgagcg gacgctccgt cacattgagt tgtcagaagg
    22021 cgagcctgcg cttgatctac tccattttca agaaaatgag gaagaatatg aagattagtc
    22081 acatgaaaaa agatgagcta tttgaaggct tttacctaat caaatcagct gacctgaggc
    22141 aaactcgagc tgggaaaaac tacctagcct ttaccttcca agatgatagt ggcgagattg
    22201 atgggaagct ctgggatgcc caacctcata acattgaggc ctttaccgca ggtaaggttg
    22261 tccacatgaa aggacgccga gaagtttata acaatacccc tcaagtcaat caaattactc
    22321 tccgcctgcc tcaagctggt gaacccaatg acccagctga tttcaaggtc aagtcaccag
    22381 ttgatgtcaa ggaaattcgt gactacatgt cgcaaatgat tttcaaaatt gaaaatcctg
    22441 tctggcaacg gattgtccga aatctctaca ccaagtatga taaggaattc tactcctatc
    22501 cagctgccaa gaccaaccac catgcctttg aaacgggctt ggtctatcat acggcgacca
    22561 tggtgcgttt ggcagacgct attagcgaag tttatcctca gctcaataag agcctgctct
    22621 atgcggggat tatgttgcac gacttggcta aggtcatcga gttgacggga ccagaccaga
    22681 ccgagtacac ggtcagaggc aatcttcttg gacatatcgc tctgattgat agcgaaatta
    22741 ccaagacagt tatggaactc ggcatcgatg ataccaagga agaagtcgtt ttgcttcgtc
    22801 atgtcatcct cagtcaccac ggcttgcttg aatatggaag tccagtccgt ccacgtatta
    22861 tggaggcaga gattatccat atgattgaca atctggatgc aagcatgatg atgatgtcaa
    22921 cagctctggc tttggtggat aaaggagaga tgtccaataa aatcttcgct atggataatc
    22981 gttccttcta taaaccagat ttagattaat aatttaagaa aaatgagcat ttttaggata
    23041 agaatgttcg tttttttatg tgaatatggt ataataagta aaagacaaaa atgaatactc
    23101 ttcgaaaatc tcttcaaact agggtagtat cgccttgtcg tatgtatata tgcaggtata
    23161 ttacagggtt tgtcagttct attgacaatc tcaaaacagt gttttgaacc accagcgacc
    23221 agctttctag tttgcttttt gattttttga ataaaaatgg aataggaaat agaaatgaaa
    23281 ttaagaagaa gtgatcggat ggttgtcatt tccaactatt tgattaataa tccttataaa
    23341 ctaactagtc tcaatacttt tgctgaaaag tatgagtctg ctaaatcatc catctcagaa
    23401 gatatcgtca ttatcaaacg cgcctttgag gaaattgaaa tcggtcatat ccagacagtg
    23461 actggggctg gcggaggtgt catcttcaca ccgtctattt cgagtcagga tgctaaggaa
    23521 atggttgaag acttgcgtac caagttgtca gaaagtgacc gtatcttgcc aggtggttat
    23581 atctatctgt ctgatttgct tagcacacca gccatcttga aaaatattgg tcgtattatt
    23641 gccaaaagct ttatggacca aaaaattgac gcggttatga ccgtagcaac taagggtgtg
    23701 ccacttgcaa atgcagttgc caatgtcctc aatgtctctt ttgtcattgt gcgccgtgac
    23761 ctgaaaatta ccgaaggttc aactgttagc gtcaactatg tttcaggttc aagtggtgac
    23821 cgtatcgaga aaatgttcct ttcaaaacgt agtcttaagg caggcagccg tgtcttgatt
    23881 gtggatgact tcttgaaagg tggcggaacg gtcaatggta tgattagtct cttgcgcgag
    23941 ttcgactcag aactggcagg tgtagcggtc tttgcggaca atgcccaaga agaacgtgaa
    24001 aagcagtttg actacaagtc actcttgaag gtaaccaata ttgatgtcaa gaaccaagcc
    24061 atcgatgttg aggttggcaa tatctttgac gaagataaat aagagataga actaaaggtt
    24121 ggaacgattg tcccagcctt tctttgcaaa cagaatagaa ggaagcttat gaaaacacca
    24181 tttatcaata gagaagagtt agaagcgatt gttgccgagt tcccgactcc ctttcacttg
    24241 tatgatgaga aggggattcg tgagaaggca agagccgtca accaagcttt ttcgtggaac
    24301 aagggcttta aggaatattt tgcagttaag gctactccaa ctccagctat tttgaaaatt
    24361 ctccaagaag aaggttgtgg tgtggactgc tctagttatg tagagctttt gatgagccat
    24421 aaactggact ttctgggttc tgagattatg ttctcttcca acaacacgcc agacaaggaa
    24481 tacgcctatg cacgtgaatt gggtgcgacc attaacttgg atgcctttga agatattgaa
    24541 catctggaga gagtagcagg cattccagaa atcatctctt gtcgttataa tcctggaggc
    24601 gtttttgaac tggggacaga cattatggac aatcctgggg aggctaagtt tggcatgacc
    24661 aaggaccagc tctttgaagc ctttgctatc ttgaaggaaa aaggagccaa gacttttggg
    24721 cttcactcct tcctagcgtc caataccgtg acccatctct attatccaga gttggctcgt
    24781 cagctctttg aactggctgt tgaaatcaag gaaaagttgg gcatttcgct agactttatc
    24841 aatctttctg gcggtattgg tgttaattat cgtccagacc aggagccgaa cgatatcgcc
    24901 ttgattggtg agggagttcg taaggtgtat gaagaagttc ttacgtcagc aggtcttggt
    24961 caggtcaaga ttttcaccga attgggtcgt tttatgctgg cacctcacgg tgctctagtc
    25021 acaagagtga ctcataagaa ggaaacctac cgtacctatc taggtgtgga tgcctcagca
    25081 gtcaacctca tgcgtccagc tatgtacgga gcttaccatc atattagcaa cgtgacccat
    25141 ccagatggac cagctgaagc ggtagatgtg gttggttcac tctgtgaaaa caatgataaa
    25201 tttgcagtca atcgcgaact gcctcataca gaaatcggtg atttgctggt cattcatgat
    25261 acaggtgctc acggtttttc aatgggttac cagtacaacg ccaaacttcg ttctgcggaa
    25321 atcctctata ccgaagaagg tgaagctcgc caaatccgcc gtgcagagcg ccctgaggac
    25381 tattttgcaa ccttatatgg attcgatttt gaagaataat ctgataatag cttgaaaatg
    25441 aaattgaaaa acagattgct ttctaaaaaa taggcaaaaa tcttgttttt ccttcaagtc
    25501 gtgatataat aaaactataa aacgttttca aggaaggtaa cgatatgtct gaagaaacaa
    25561 ttgattatgg acaagtgaca ggaatggtgc attcgacaga aagctttggg tcagtagatg
    25621 ggcctggtat tcgctttatt gtctttttgc agggctgtca catgcgttgc cagtattgcc
    25681 acaacccaga cacttgggct atggagtcca ataagtcacg tgaacggacg gtagatgatg
    25741 tcttgacaga ggccttgcgc taccgtggtt tctggggaaa taagggtggg attacagtca
    25801 gtggaggaga agctctcttg cagattgatt tcctgattgc cctcttcacc aaggctaagg
    25861 aacaaggaat ccactgtacc ttggatacct gtgctcttcc tttccgtaat aaaccacgtt
    25921 accttgagaa gtttgacaaa ctcatggctg tcactgactt ggttcttttg gatatcaagg
    25981 aaatcaacga agaacagcac aagattgtca ctagacaaac taataaaaat atcttggctt
    26041 gtgcccagta tctatcagat attggaaaac ctgtctggat tcgccacgtg ctagttccag
    26101 gattgacaga cagagatgat gacttgattg aacttggtaa gttcgtcaag accctcaaaa
    26161 atgttgataa gtttgaaatt ctaccttatc acaccatggg tgagttcaag tggcgtgaac
    26221 ttggaattcc atattccctc gaaggagtca aaccaccaac agcagatcgc gtcaagaacg
    26281 ctaaaaaact catggatacc gaaagttatc aagattatat gaaacgtgta catggataga
    26341 aaagaagcct gatggaaaca tcgggctttt gatttgcaaa aagacttagc aaatcagcta
    26401 agcctttttc ttcttatctc gaacgttgtt ttccagcgtt gcgatttttg tgttttttct
    26461 tgcttgtgat agcagttggt tgttcagggg taacgtcttt tcgtccactt ggtttagaga
    26521 aagcacttgc ttttggtggg ttcttggcta gttcttcacg gacttttttg cgaagttttg
    26581 gacgaacgat atagttgacg ataaactgtt ggagaatcat catgaaacca ccgacaaccc
    26641 agtaaagtgt gacactagct ggtgagaaga gggagaagac gacgatcatg agtgggctca
    26701 tgtaaatcat tttcttgatt tgttctcttt gcatttcatc ttctactccg tgaagtgaaa
    26761 ggagcgattg aagatagtaa aggacaccag cacaggcaac caaaatcata cttggagaac
    26821 ctagaggaat gcctaggtag cttgcttgag caaccccttc agtatgttgg gcagcaaagt
    26881 agatagcaga gaagaaaggc atttgaagga ggatagggaa acatcctaca ccaccaaaca
    26941 tgctgatgcc gtgctctttt tgagcggcaa agagggcttg ttgggcttcg agtttttctt
    27001 cttgagtagt tgcttctttg agacgtgttt ggtgtggctc aaggacatgc ttgagagcgt
    27061 tcatcttttc agagtgaagc gttgccttcc atgattggta gataccaagt ggtaagataa
    27121 tcaagcgtac gataatggtt acgataatga tagcgacacc aaagcctaga cctttatcag
    27181 tagcgaagta cttgatggct tcagccatag gcgctccgat cgtattccaa ataaatcctg
    27241 ttggctgacc tgtggtttta tcgacattga cacagccagt caagacaagc aacatagcca
    27301 ctcccatagc cgagaatgca aaacgtttaa tagatttcac tgtttttatt ccttctttaa
    27361 aaattatacc tttctattct actgtttttt tacaaaatat acaatagttc tggagaccta
    27421 atttgcgatt ttaaagtcag agtagggagg aaagttgctt agtttgacat ctaagtagct
    27481 tacttttgaa aaaggtgtcg gtccttttcg gatttcttgg ataaattttg ccatgatagc
    27541 agatgagtct gcttgggcta agatttccac tgtgccatcg tcgttattcc atactcgacc
    27601 tgtgatgcca ccaatttcaa gtgccaagct gtaaacaccc caacgaaagc cgactccctg
    27661 taccctacct tgggcaatca ttctaacctt ttgcatacca accccctttg attgtgttat
    27721 aatatttcta tgactattat aacctcaaaa gccaattctg tggtaaaaaa tgccaagaaa
    27781 ttacgccaaa aaaaataccg caagtctgcc tatttgattg aaggctggca cttgtttgaa
    27841 gaagctgtcc aagctggagt gacgattgag aaaatctttg ccctagaaaa ttatcgagat
    27901 cagttagcta ctttttcgca aactgtctgg gtgtcagagg atattttgct agatttggcg
    27961 gattctcaga ctccacaggg aattgtggcg gtggttcaaa aagaagaagt aggacaagct
    28021 gatttgagtc agggcaagtt cttgtttttg gaagatgtgc aagatcccgg taatgtagga
    28081 actatcattc gaactgcgga tgcagcaggt tttacaggag tgattgtttc agataagtcg
    28141 gcagacatct acagtctcaa aaccctacgt tccatgcaag gtagtcattt ccatctgccc
    28201 atttaccgga tgactagtcc agcgcttctt gacgaaacta aaaaggtagc tatcccagtg
    28261 ctagcaacaa ccctatctaa agattctgtt gattacagag aactgccttc tatagaaaat
    28321 tttgtactag ttatgggaaa tgagggtcaa ggaattagtc cccttatggc tgaaagtgca
    28381 gaccagttgg tccatattag catgaagggg caggccgaga gtttgaatgt tgcagttgca
    28441 gccggtattt taatcttcca tttaagctaa ttttaacttt ttttgttata atcaaggaaa
    28501 gatgttcaca gaaaaggaga aatggatgaa tcacactatt atacatgacc gtgcaggtct
    28561 caatcaattt tacgctaagg tttatgcctt tgttggtctg ggaatcggac tatctgcttt
    28621 ggtatcaggc cttatgttga cggtctttca gtctcagttg gtttacttgt tgatgcaggg
    28681 gcgtctctgg ttgaccattg ctacttttgc ggagttggct ttggttttcg ttgccagtag
    28741 catggcttca agaaatagtc cagctgctct tccagtattt ttactttact ccgttttaaa
    28801 cggctttacc cttagttttg tggtggcttt ctatactccg ggtacagttt tatctgcctt
    28861 tgtatcgagc gcccttctct tctttgtcat ggcggcagtt ggtatcttta ccaagaaaga
    28921 cttgagtggg attggtcgag caatgatggc agctctcatt ggtttactga ttgctatggt
    28981 agtcaatatt ttcttggcta gtggcttctt tgattatatg attagcgtag ccatggtttt
    29041 ggttttttca gggttgattg cttgggataa ccaaaagatt cgcctcgcct atgaacaatc
    29101 acaaggtcgt gtagcgacag gctgggtggt gtcaatggct ctcagcatct atcttgattt
    29161 tatcaatctt ttcctaagta ttctacgtat ctttggtcgc aatgactaaa aggtctatga
    29221 aatcagtgtt ttgagtgaca ctgatttttt ttaaattttc tcttttcttt tcttggaaat
    29281 aggtgtataa tacgtttatt aaatttttga ggagttgtct atgaagaaaa gttttatcca
    29341 tcaacaagaa gaaatttcct ttgtcaaaaa cacttttacc cagtatttga aagataagct
    29401 agaagttgtc gaagttcaag gtcctatctt gagtaaggtc ggtgacggaa tgcaggacaa
    29461 cctgtctggt gtggaaaatc cagtatcggt caaggttctc caaatccctg atgctactta
    29521 tgaagtggtg cactcacttg ctaaatggaa acgccacacc ttggctcgtt ttggctttgg
    29581 tgaaggagag ggtctctttg tccacatgaa agcccttcgt ccagatgagg attccttgga
    29641 tgcaacccac tctgtttatg ttgaccagtg ggactgggag aaggttatcc caaatggtaa
    29701 gcgtaacatc gtttatctaa aagaaacagt tgagaagatt tataaggcta ttcgcctgac
    29761 tgagctagct gttgaagccc gctatgacat cgagtctatc ttgccaaaac aaatcacctt
    29821 tatccataca gaagaattgg tagaacgcta cccagacttg acaccgaaag aacgtgaaaa
    29881 tgcgatttgt aaagaatttg gagccgtctt tttgattggt atcggtggcg agttgccaga
    29941 tggtaaaccg cacgatggac gtgcaccaga ctatgatgac tggacaagcg agtctgagaa
    30001 tggctacaag ggtctaaatg gtgatattct tgtctggaat gagtctttag gtggagcctt
    30061 tgagttgtct tctatgggaa ttcgtgtaga tgaagaaact cttagacgtc aggtggaaat
    30121 tacaggtgat gaagaccgct tggaattgga atggcacaag tctttgttga atggtctatt
    30181 cccattgaca atcggtggag gaattggaca atctcgtatg gccatgttcc tacttcgcaa
    30241 gagacacatc ggagaagtgc aaacaagtgt ttggcctcaa gaagtccgcg atacttacga
    30301 aaatattttg tagagaatcg aaccgcaagg ttcggttttc tttctctttt tgtctataat
    30361 ttggtataat aaacagtatg aaaatcgtat caggaatcta tgggggacgt cccctcaaga
    30421 cactagaagg caagacaaca agacctactt cggataaggt taggggagcc atttttaaca
    30481 tgattggtcc ctactttgaa gtgggacgag tcttggacct ttatgcaggt agtggtggtt
    30541 tatctatcga agcagtatcg cgtggcatgt ccagtgctgt tttggtggag cgagaccgta
    30601 aggctcagac catcgtggct gaaaatatcc agatgaccaa ggaagttgga aaatttcaac
    30661 tcctcaaaat ggatgcagaa agggcattgg aacaggtatc tggggaattt gacctcgttt
    30721 tcttagaccc tccctatgcc aaggaacaaa tcgtagcaga tattgaaaaa atggctgaga
    30781 gagagctttt ttctgaagat gttatggttg tgtgcgagac ggataaggcc gttgaacttc
    30841 cagaagagat tgcctgtctg ggtatctgga aggaaaagat ttatggaatt agtaaggtga
    30901 cagtctatgt cagataagat tggcttattc acaggctcat ttgatccgat gacaaatggg
    30961 catctggata tgattgaacg ggcgagcaga ctctttgata agctttatgt gggtattttt
    31021 tttaatcccc acaaacaagg atttctccct cttgaaaatc gtaaacgggg gctagaaaag
    31081 gctgtgaaac atttgggaaa tgttaaagtc gtgtcttctc atgataaatt ggtggtcgat
    31141 gtcgcaaaaa gactgggggc tacttgccta gtgcgaggct tgagaaatgc gtcggatttg
    31201 caatatgaag ccagttttga ttactacaat catcagctgt cttctgatat agagactatt
    31261 tatttacata gtcgacctga acatctctat atcagttcat caggcgttag agagcttttg
    31321 aagtttggtc aggatattgc ctgctatgtt cccgagagta ttttggagga aataagaaat
    31381 gaaaaaaaag attagatggc ccttatacgt cattgcggcc ttgattgtga ctttcttggc
    31441 atttgtagtg cccttgcctt attatataga ggttccaggt ggttcggaag atattcgcca
    31501 agtccttaaa gtaaatgaca cagaagataa ggaagctggt gcctatcaat tcgttacggt
    31561 tggtgttcaa catgccactt tagctcatat aatttatgct tggttgacac cttttacaga
    31621 tattcgtagt gctcaggaga ctacaggtgg ttcttccgat gttgaattta tgcgaatcaa
    31681 tcaattctac atgcaaacat cgcaaaatat ggccaagtat caaggactaa aaacagctgg
    31741 taaggatatc gaactcaagt actttggagt ttatgttttg aatgtgacgg ataattcaac
    31801 ctttaaaggg attctcaata tctctgatac agtcacagca gtcaatgatc agacctttga
    31861 tagttccaaa gacttgattg attacgtcag ttctcaaaaa ttaggggctt ccgtcaaggt
    31921 cacctatgaa gaggatgggc aaaccaagtc tgcagaagga aaaatcatca ccttggaaaa
    31981 tggcaaaaat ggaattggaa tcggcttgat tgaccgtaca gaggtaatca gcaatgtccc
    32041 aattagcttt tcaacagctg gtattggcgg tccaagtgct ggtctcatgt ttagtctagc
    32101 tatctatact caaatagctc acccagatct tcgtaatggt cgtattgttg ccggtacagg
    32161 taccattgac cgcgatggta atgtgggaga cattggaggt attgataaga aggttgtagc
    32221 ttcggctagg gcaggtgctg ctattttctt tgctcctgat aaccctgtta gcgaagaaga
    32281 acaaaaggcg catccggacg cgaaaaacaa ctaccaaaca gccctagaag cggctaaaac
    32341 aatcaagacg gatatgaaaa tcgtgcccgt taaaacccta caagatgcga ttgattactt
    32401 gaaaaacaat ccctaatttt tgagtgaagt ttccaaacta gcgcacaaac agagaagatg
    32461 gtataatagt caaatggttc aattattatt cactctaagt agtcatatgc tctttattta
    32521 tgtgagtttt taccttttaa aggatcttgt tagatgggag aaggttttaa aagtgacaga
    32581 tgataataca agaaaagttc gtttattagt agcctttttt agcattgtca taggctacat
    32641 cctgagttct ttctttatta gcctgtatca tttatggcaa gaagcgctta gaggattatt
    32701 ataaaatcaa gagtaaagga aacgagtatg gataaaattg tggttcaagg tggcgataat
    32761 cgtctggtag gaagcgtgac gatcgaggga gcaaaaaatg cagtcttacc cttgttggca
    32821 gcgactattc tagcaagtga aggaaagacc gtcttgcaga atgttccgat tttgtcggat
    32881 gtctttatta tgaatcaggt agttggtggt ttgaatgcca aggttgactt tgatgaggaa
    32941 gctcatcttg tcaaggtgga tgctactggc gatatcactg aggaagcccc ttacaagtat
    33001 gtcagcaaga tgcgcgcctc catcgttgta ttagggctaa tccttgcccg tgtgggtcat
    33061 gctaaggtat ccatgccagg tggttgtacg attggtagcc gtcctattga tcttcatttg
    33121 aaaggtctgg aagctatggg ggttaagatt agtcagacag ctggttacat cgaagccaag
    33181 gcagaacgct tgcatggcgc tcatatctat atggactttc caagtgttgg tgcaacgcag
    33241 aacttgatga tggcagcgac tctggctgat ggggtgacag tgattgagaa tgctgcgcgt
    33301 gaacctgaga ttgttgactt agccattctc cttaatgaaa tgggagccaa ggtcaaaggt
    33361 gctggtacag agactataac cattactggt gttgagaaac ttcatggtac gactcacaat
    33421 gtagtccaag accgtatcga agcaggaacc tttatggtag ctgctgccat gactggtggt
    33481 gatgtcttga ttcgagacgc tgtctgggag cacaaccgtc ccttgattgc caagttactt
    33541 gaaatgggtg ttgaagtaat tgaagaagac gaaggaattc gtgttcgttc tcaactagaa
    33601 aatctaaaag ctgttcatgt gaaaaccttg ccccacccag gatttccaac agatatgcag
    33661 gctcaattta cagccttgat gacagttgca aaaggcgaat caaccatggt ggagacagtt
    33721 ttcgaaaatc gtttccaaca cctagaagag atgcgccgca tgggcttgca ttctgagatt
    33781 atccgtgata cagctcgtat tgttggtgga cagcctttgc agggagcaga agttctttca
    33841 actgaccttc gtgccagtgc agccttgatt ttgacaggtt tggtagcaca gggagaaact
    33901 gtggtcggta aattggttca cttggataga ggttactacg gtttccatga gaagttggcg
    33961 cagctaggtg ctaagattca gcggattgag gcaagcgatg aagatgaata agaaatcaag
    34021 ctacgtaatc aatcgtttac ttttagtcat catagtactg attttaggta ctctggctct
    34081 aggaatcggt ctaatggtag gttatggaat cttgggcaag ggtcaagatc catgggctat
    34141 cctgtctcca gcaaaatggc aggaattgat tcataaattt acaggaaatt aggctggaga
    34201 accagccttt ttctaaagat aaggagaaat atgaacaaaa aaacaagaca gacactaatc
    34261 ggactgctag tgttattgct tttgtctaca gggagctatt atatcaagca gatgcagtcg
    34321 gcacctaata gtcccaaaac caatcttagt cagaaaaaac aagcgtctga agctcctagt
    34381 caagcattgg cagagagtgt cttaacagac gcagtcaaga gtcaaataaa ggggagtctg
    34441 gagtggaatg gctcaggtgc ttttatcgtc aatggtaata aaacaaatct agatgccaag
    34501 gtttcaagta agccctacgc tgacaataaa acaaagacag tgggcaagga aactgttcca
    34561 accgtagcta atgccctctt gtctaaggcc actcgtcagt acaagaatcg taaagaaact
    34621 gggaatggtt caacttcttg gactcctcca ggttggcatc aggtcaagaa tctaaagggc
    34681 tcttataccc atgcagtcga tagaggtcat ttgttaggct atgccttaat cggtggtttg
    34741 gatggttttg atgcctcaac aagcaatcct aaaaacattg ctgttcagac agcctgggca
    34801 aatcaggcac aagccgagta ttcgactggt caaaactact atgaaagcaa ggtgcgtaaa
    34861 gccttggacc aaaacaagcg tgtccgttac cgtgtaaccc tttactacgc ttcaaacgag
    34921 gatttagttc cctcagcttc acagattgaa gccaagtctt cggatggaga attggaattc
    34981 aatgttttag ttcccaatgt tcaaaaggga cttcaactgg attaccgaac tggagaagta
    35041 actgtaactc agtaaaagat aagcctaaac tcctatgtca cttatggatg taggagttct
    35101 ttttactagt ttaagcaggg ctagaatagg tactaagaaa aaatagtaac ttctaaaact
    35161 aacttccagt ttcccacaac ctagctttta gtatgagaaa aacgcgtgaa atcagtggaa
    35221 atccgtctta gactaacttc cagttttggg agagagatgg aagttacgct aagaaaaaaa
    35281 taatatgtat tggattaaat tttgtgatat aataaaggat aagatactat tttaggagaa
    35341 gaactatgga agacccaagt agtcagaatt tgttgctaca atttgtttta ttgtttatct
    35401 tgacggtatt aaatgccttt ttctcagcca cagaaatggc catggtttct cttaatcgtg
    35461 cccgagttga acaaaaggcg gaagaaggag acagacgcta catccgcctg ctgaaggtac
    35521 tagaaaatcc taaccacttt ttatcaacca ttcaggtagg aatcaccctg attacaatct
    35581 tatcaggggc gagtttaact gatactctag gacgtgtgat tgcctcttgg cttgggaatg
    35641 gcgaaacagc acaagccgtg gcaacttttc tatccttggc atttttgacc tatatttcca
    35701 tcgtttttgg ggaattatat cctaagagaa tcgctcttaa tctaaaggat gccttggcaa
    35761 ttcgtacagc gccgattatc attgggatcg gaaaactagt cagtcctttt gtttggcttt
    35821 tagctgcttc gaccaatttc ttgagccatt tgactcctat gtcattcgat gatgcggatg
    35881 aaaagatgac ccgtgatgaa attgcctata tgctgacaaa tagtgaagaa acattggatg
    35941 ctgatgagat tgagatgcta caaggtgtct tttcgctcga tgaactgatg gcacgagagg
    36001 ttatggttcc tcgaacggat gcctttatgg tggatattca ggatgatagt caagccatta
    36061 tccaaagtat tttaaaacaa aattattctc gtatcccggt ttatgatggg gataaggaca
    36121 atgtaattgg aatcattcac accaagagtc tccttaaggc aggctttgtg gacggttttg
    36181 acaatattgt ttggaagaga attttacaag atccactttt tgtacctgaa actatttttg
    36241 tggatgactt gctaaaagaa ctgcgaaata cccaaagaca aatggcaatc ttgctggatg
    36301 aatacggtgg tatggctggt ttggtgactt tggaagacct cttagaggaa attgttggtg
    36361 aaattgatga tgaaacggac aaagcagcaa tagatgttca tcagattggc gaggatacct
    36421 acattgttca aggaactatg accctcaatg atttcaataa ttactttaat gttgaactgg
    36481 aaagtgatga cgttgatact atcgctggtt attatttgac aggagtggga accattccaa
    36541 cgactgagaa actcagctat gaattggtca gccaaaacaa acagtttatc ttaaccaatg
    36601 ataaagtgaa gaatggacgt gttaccaagg taaaagtcca aatcacagaa gtcgaaatag
    36661 aagaagaaac agaataaact agaggctttt gtcaccaggc gtgacgaagc ttttttcaat
    36721 tgatttcaaa agggaattat gccatggaaa gaactctgcc acaaactcgc tccaaaagtt
    36781 tttaaagtta tacgtattta ttcgagggaa aataagaaaa gcccttcaaa ttgggctttc
    36841 tgttcatttg aaacctgata aatcaagtta tagaaggcgg tagacggatt tgaaccgacg
    36901 atcaagcttt tgcagagccg tgccttacca cttggctata ccgccttaac gtttattatt
    36961 ataccttgaa aatgattttc agtcaatagt tttttcagtt ttttgtacca tagcgtgatt
    37021 cgaatgtgat gccaagtttt ctatgggaaa aaatttacaa aaaacctact gaaacccctt
    37081 gaaaaatcta gctaaatagg gtataatatg ggtaatcatt tgtcgtaggt tttgtctgaa
    37141 atattgtcca gacaaggctc acagcagtta aatcttctga aaaagtcaga tttagctgct
    37201 ctttttgtgc tttttttcaa gattttgagc atttgtaaca gaggcttaaa gattctgaaa
    37261 aatcgtcaag aggacacggt gataaggggt ttacaaccat atgacgatta gaaaagcctg
    37321 attgacaagg cttggaactt atttacaaag gagaatcatc ttggcaggac atgacgttca
    37381 atacgggaaa catcgtaccc gtcgtagttt ttcaagaatc aaagaagttc ttgacttacc
    37441 aaatttgatt gaaattcaaa ctgactcatt caaagctttc ctagaccacg gtcttaagga
    37501 agtgtttgaa gatgtattgc caatttcaaa cttcacagac acaatggagt tggaatttgt
    37561 tggatatgaa atcaaggaac caaaatacac gctagaagaa gctcgtatcc acgatgctag
    37621 ctactcagca ccaatttttg taaccttccg tttgatcaat aaagaaacag gcgaaatcaa
    37681 gacccaagaa gttttctttg gtgatttccc aatcatgaca gaaatgggta ctttcatcat
    37741 caatggtggt gaacgtatta tcgtttctca gttggtccgc tcaccaggtg tttactttaa
    37801 cgacaaagta gacaaaaatg gtaaggtggg ctatggttca actgttatcc ctaaccgtgg
    37861 agcttggttg gaacttgaaa gcgactcaaa agatatcacc tacactcgta tcgaccgtac
    37921 tcgtaagatt ccatttacaa ccttggttcg tgctcttggt ttctcaggtg atgatgaaat
    37981 ctttgatatc tttggtgaca gcgaattggt tcgcaacact gttgaaaaag atatccacaa
    38041 gaatccaatg gactctcgta cagacgaagc cttgaaagaa atttacgaac gccttcgtcc
    38101 aggtgagcct aagacagctg aaagctcacg tagcttgctt gtggctcgct tctttgaccc
    38161 acgtcgctat gacttggcag cagttggtcg ttacaaaatc aataaaaaac tcaatgttaa
    38221 aacacgtttg ctcaaccaaa ccattgcaga gccattggta gaccctgaaa ctggagaaat
    38281 cttggtagaa gctggtacga ttatgactcg tagcgtgatt gaaagcattg aaagccattt
    38341 ggatggcgac ttgaacaaga ttgtctacat cccaaacgat gcagccgttg tgactgagcc
    38401 tgttgttctt caaaaattca aggttgttgc tccaactgat ccagatcgcg tcgtaacgat
    38461 cattggtaat gctaacccag atgacaaggt tcgtacggtg actcctgcag atatccttgc
    38521 tgagatgagc tacttcctca acttggctga aggacttggc cgtgtagatg atatcgacca
    38581 ccttggaaat cgtcgtatcc gtgcggttgg tgaattgctt gccaaccaag tacgtttggg
    38641 actttctcgt atggaacgta atgtccgtga acgtatgtct gttcaggaca atgaagtctt
    38701 gacaccacaa caaattatca atatccgtcc tgtaacagct gcggttaaag aattctttgg
    38761 ttcatcacag ttgtcacagt tcatggacca acacaacccg ctttctgagt tgtctcacaa
    38821 acgccgtttg tcagccttag gacctggtgg tttgactcgt gaccgtgccg gatatgaagt
    38881 acgtgacgtg cactacactc actatggtcg tatgtgtcca atcgagacac ctgaaggacc
    38941 taacatcggt ttgatcaata acttgtcatc ttacggacac ttgaacaaat atggttttgt
    39001 tcaaacacca taccgtaagg ttgaccgtga aacaggtgtt gtcacgaacg aaattgtttg
    39061 gttgacagct gatgaagaag atgaatatac tgtagctcag gctaactctc gtctgaatga
    39121 agatggaacc tttgctgaga agattgtcat gggacgtcac caaggggtca accaagagta
    39181 tccagctaat attgttgact acatggacgt ttcaccaaaa caggtagttg ccgttgcgac
    39241 agcatgtatt cctttcttgg aaaacgatga ctccaaccgt gccctcatgg gagccaatat
    39301 gcaacgtcag gctgtgccat tgattaatcc tcaggcacct tacgttggta ctggtatgga
    39361 ataccaagca gcccacgatt ctggtgcggc tgtgattgct cagtatgatg gtaaagttac
    39421 ttacgcagat gctgacaagg tagaagttcg tcgtgaagat ggttcattgg atgtttacca
    39481 catccaaaaa ttccgtcgtt caaactcagg tactgcttac aaccaacgca ctctcgtaaa
    39541 agttggtgat gtcgttgaaa aaggcgattt catcgctgac ggaccttcta tggaaaatgg
    39601 agaaatggcg cttggacaaa acccaatcgt tgcctacatg acttgggaag gttacaactt
    39661 cgaggatgcc gttatcatga gcgaacgctt ggtgaaggac gatgtctaca catctgttca
    39721 ccttgaagaa tacgaatcag aaacgcgcga tacaaagctt gggcctgaag aaatcactcg
    39781 cgaaattcca aacgttggtg aagatgccct caaagacctt gacgaaatgg ggattatccg
    39841 tattggtgct gaggttaaag aaggtgatat tcttgtaggt aaagtaacac ctaagggtga
    39901 gaaagatctt tcagctgaag aacgtctctt gcacgctatc tttggagaca agtctcgtga
    39961 agtgcgtgat acttctcttc gtgtaccaca cggtgccgat ggtgtcgttc gtgatgttaa
    40021 gatctttaca cgtgtaaatg gagatgagtt gcaatcaggt gttaacatgt tggttcgtgt
    40081 ttacatcgct caaaaacgta agattaaggt cggagataaa atggccggac gtcacggaaa
    40141 caaaggggtt gtctctcgta tcgttcctgt agaagacatg ccttaccttc cagacggaac
    40201 tccagtcgac atcatgttga acccacttgg ggtgccatca cgtatgaata tcggtcaggt
    40261 tatggagctt caccttggta tggcagctcg tactcttggt attcacattg cgacaccagt
    40321 ctttgatgga gcaagttctg aagatctttg gtcaactgtt aaagaagcag gtatggatag
    40381 cgatgccaag acaatccttt acgatggacg tacaggtgaa ccatttgata accgtgtttc
    40441 tgttggagtc atgtacatga tcaaactcca ccacatggtt gacgataaat tgcatgcgcg
    40501 ttcagtcgga ccttactcaa ctgttaccca acaaccactc ggaggtaaag ctcagtttgg
    40561 tggacaacgt ttcggtgaga tggaggtttg ggctcttgaa gcctacggtg cgtcaaatgt
    40621 ccttcaagaa atcttgactt acaagtcgga cgatatcaac ggacgtttga aagcctatga
    40681 agctattaca aaaggcaaac caattccaaa accaggtgtt ccagaatcct tccgagttct
    40741 tgtcaaagaa ttgcaatctc ttggtcttga catgcgtgtc ctagacgaag atgaccaaga
    40801 agtggaactt cgcgacttgg atgaaggaat ggacgaagat gtcatccacg tagatgacct
    40861 tgaaaaagcc cgcgaaaaag cagcccaaga ggctaaagca gcctttgaag ctgaagaagc
    40921 tgagaaagca acaaaagcgg aagcaacaga agaagctgct gaacaagaat aagcagttca
    40981 cttagaatag aaagggaaga aatagtggtt gatgtaaatc gttttaaaag tatgcaaatc
    41041 accctagctt ctccaagtaa agtccgttca tggtcttatg gagaagtcaa aaaacctgaa
    41101 acaatcaatt atcgtacctt gaaaccagaa cgtgaaggac tctttgatga agtgatcttt
    41161 ggtcctacaa aagactggga atgtgcttgt ggtaagtaca aacgcattcg ttacagagga
    41221 attgtttgtg accgctgtgg ggttgaagta acgcgtacga aagttcgtcg tgagcgtatg
    41281 ggacatatcg aattgaaagc tcctgtatct cacatctggt acttcaaggg gattccaagc
    41341 cgtatgggct tgacccttga tatgagccct cgtgccctcg aggaagttat ctactttgcg
    41401 gcttatgtgg tgatcgatcc taaggataca ccacttgagc acaagtctat catgacagag
    41461 cgcgaatacc gagagcgctt gcgtgaatat ggttatggtt catttgttgc caagatgggt
    41521 gcggaagcca tccaagacct tttgaagcaa gtagatcttg aaaaagaaat tgctgaactc
    41581 aaagaagaat tgaaaacagc tactggacaa aaacgtgtca aagccatccg tcgtttggat
    41641 gttttggatg ccttttacaa gtctggaaac aaacctgaat ggatgattct taacattctt
    41701 ccggttatcc caccagatct tcgtccaatg ttgcagttgg atggtggccg ttttgcctca
    41761 tctgacttga atgaccttta ccgccgtgtt atcaaccgta acaaccgttt ggctcgtttg
    41821 cttgagttaa atgcaccagg tatcatcgtt caaaatgaga agcgtatgct tcaagaagca
    41881 gttgacgctt tgattgacaa tggtcgtcgt ggtcgtccaa tcacaggacc aggtagccgt
    41941 ccattgaaat cattgagcca catgcttaaa ggtaaacaag gacgcttccg tcaaaacttg
    42001 ctcggtaaac gtgttgactt ctcaggacgt tccgttatcg ccgttggtcc aactcttaag
    42061 atgtaccaat gtggtgtgcc acgtgaaatg gcgattgaac tctttaaacc atttgtcatg
    42121 cgtgaaatcg ttgcccgtga tatcgtgcaa aacgtcaaag cagctaaacg cttggtggaa
    42181 cgcggagatg agcgtatctg ggatatcctt gaagaagtga ttaaagaaca cccagtgctt
    42241 ttgaaccgcg caccgaccct tcaccgtttg ggtatccaag ccttcgagcc agtcttaatt
    42301 gatggtaagg ctcttcgctt gcacccactt gtctgtgaag cctacaatgc cgactttgac
    42361 ggggaccaaa tggccatcca cgtaccactt tcagaagaag cacaagcaga agctcgtatc
    42421 ctcatgctag ctgctgagca catcttgaac ccgaaagatg ggaaaccggt agttactcca
    42481 tctcaggaca tggttttggg taactactac ttgaccatgg aagaagctgg tcgcgaaggt
    42541 gaaggaatgg tcttcaaaga ccgtgacgaa gcggttatgg cttaccgcaa tggttatgtt
    42601 cacctccact cacgtgttgg tatcgcaaca gacagcctca acaagccttg gacagaagag
    42661 caaagacata aggtcttgct tacaacagtt ggtaaaattc tcttcaacga tatcatgcca
    42721 gaggggctac catacttgca agaaccaaac aatgccaact tgacagaagg tgttccagct
    42781 aaatacttct tgccacttgg tggagatatc aaggaagcta tcagcaatct tgagctcaac
    42841 cctccattca agaagaaaaa ccttggaaat atcatcgctg aaatcttcaa acgtttccgt
    42901 acgacagaaa cttctgccct acttgaccgc atgaagaacc tcggttacca ccactcaact
    42961 cttgcaggat tgacagtggg tattgccgac atcccagtcg ttgatgacaa ggctgaaatc
    43021 attgaagaat cacacaaacg tgtcgaacaa atcaccaaac aattccgtcg tggtatgatc
    43081 acagacgacg agcgttacaa tgctgttaca gctgaatggc gtgctgcccg tgaaaaactt
    43141 gagaaacgct tgattgctaa ccaagatcct aagaacccaa tcgttatgat gatggactct
    43201 ggagcccgtg gtaacatctc aaacttctca cagcttgccg gtatgcgtgg tctgatggct
    43261 gctccgaatg gacgtatcat ggaattgcca atcctttcaa acttccgcga aggtttgtcg
    43321 gtattggaaa tgttcttctc aactcacggt gctcgtaaag gtatgaccga tacggccctt
    43381 aagacagccg actcaggtta cttgactcgt cgtttggtcg acgttgccca agacgttatc
    43441 atccgtgagg acgactgtgg aactgaccgt ggtctcttga tccgttctat cgcagaagga
    43501 aaagagatga tcgagtctct cgaagagcgt ctcaacggtc gttacactaa gaaaactgtt
    43561 aaacatccag aaactggtgc agtgattatt ggtccaaatg aattgattac agaagacaag
    43621 gcgcgtgaaa ttgtcaatgc tggtgtggaa gaagtgacta tccgttctgt atttacatgt
    43681 aacactcgtc acggtgtctg ccgtcactgt tacggtatca acttggcgac tggtgatgcg
    43741 gttgaagttg gtgaagcagt tggtacaatc gctgcccaat ctatcgggga acctggtaca
    43801 cagcttacaa tgcgtacctt ccacacaggt ggggttgcct caaataccga tatcactcag
    43861 ggtcttcctc gtgtccaaga aatctttgaa gcccgcaatc ctaaagggga agcggttatt
    43921 acagaggtta aaggacaagt tactgctatc gaagaagatg catcaactcg taccaagaaa
    43981 gtctttgtta agggtgaaac tggcgaaggt gaatatgtcg ttccatttac agctcgtatg
    44041 cgtgtcgaag ttgggggcca agtagcgcgt ggtgctgctc tgacagaagg ttctatccaa
    44101 ccaaaacgtc tccttgcagt tcgtgatgtc ttgtcagttg aaacgtacct tctcggtgaa
    44161 gtacaaaaag tttaccgtag ccaaggggta gaaatcggtg acaaacacat cgaggtaatg
    44221 gttcgtcaaa tgatccgtaa agtccgtgtc atggatccag gtgatacaga tcttctcatg
    44281 ggtaccctca tggatatcaa tgactttaca gatgccaaca aagatgtcct tatcgcaggt
    44341 ggagttccag cgacaggtcg cccagtcctt atgggaatta ccaaagcctc acttgaaaca
    44401 aacagtttct tgtcagcggc ttccttccag gaaacaactc gtgtccttac tgacgcagct
    44461 atccgtggta agaaagacca tctccttgga cttaaagaaa atgttatcat cggtaagatc
    44521 atcccagctg gtactggtat ggcccgttac cgtaaccttg aaccacatgc tgtcaacgaa
    44581 gaagaatacc ttaatcctcc agtagaggaa gaaggaaatg aagaaacaac agaagtagtt
    44641 gtggatactg ccgttgaaac tgtggaagaa acagtagaat aagagagaat gagagaaccc
    44701 gagggttctc tcattctctc ttctgaaaac tttctccatt tttccacgaa atgtggtaaa
    44761 ataaaagaaa gaagctgaca aaggagacgg gtatggaaca aacattcttt atcatcaaac
    44821 cagatggtgt aaaaagaggg ctagtgggtg aagtgttaaa gcgcatcgaa caacgtggat
    44881 ttacaatcga aaaattggag tttcgttcac aggtttcaga agagttgatt gaccagcact
    44941 atcaggactt ggttggtcag agtttttacc taccgattcg tgaattcatg acttcaggtc
    45001 cagttcttgt gggtgtcatt tctggtccca aagtaatcga aacttggcgg accatgatgg
    45061 gtgcaactcg tccagaagaa gctttaccag gcactattcg aggtgacttt gcaaaagctg
    45121 ctggagaaaa tgaggttatc caaaatgttg tacatggttc agattcagaa gagtcagcta
    45181 agcgagaaat tgctctttgg ttttaagagt ggattggctc aatcaattgg ttaaaagctc
    45241 atttgaatag aaagtatagt caattagttt aagacatgac gcatgatatc aaacttttta
    45301 gtttttgata tggagcgttt tttgattaag tgactattag ttcgtctcgc tccgttaggt
    45361 gcgagacaaa aaaaacaccc gctatgcggg tgcgcgtcga aggttatacc aaaaaaactc
    45421 caaacgcgat acaataaagg tgttcaatcc aattgtaaag cgaaaggaga aaaatatggc
    45481 acaaaaggtt cttttatcct gttcttgttt caattgacta tatttctata ctttttcttc
    45541 ctttctctgt gaaaatcgca agtttttccc accttttctc aatactgaaa caacatcttt
    45601 ccagaacttc aataatttct ttttgtgtta aatcattatt taactaaatc tttggaggca
    45661 atacgttttc aaagcgactt ttttaccata ggttttgagc cttcaacaca gattactaag
    45721 ccaaaaatgc tctaaatttt tgaaattcta acaaattcca ctcaacttta tcatcatctt
    45781 tgactttcac aatatcttcc tcaaaataac atggaataaa gatagttttc ttttaaaacg
    45841 gttgtaggag gaaaatctct cctacactat tattgattct gagagaaaat tgcaaaatat
    45901 catctaccaa actttcaatt attaagattt tttgcagttt atctgaatta gaatcgcaag
    45961 gcttctcaat aatataattg tcgaattttt tcattctaac ttcctctcca ttatttcttc
    46021 ctttatcaag aaaaagttac ctcaatatta ataaagtaca attctaaatt aactccaatt
    46081 cttgattcat gataatattt cagtaactca tcgtgcaatt aaaaacaagg atttttattt
    46141 cagatgatcc atcgtgaaca cttcatcagc catctcccaa attgccggat tatgtgttgc
    46201 gataatgatt agcctattat catctcgaag agatagcaaa atctccataa tcaactgaga
    46261 ggttgctggg tctattgaag ctgttggctc atctgccaga ataaagggtg gattctttaa
    46321 gataactttt gccaaggcaa cccgttgcga ttctccgccc gataactcaa agatgcgctt
    46381 atctaggtca agataagcca ggccgacctg ttctaaagcc tgcttctgcc tcaaccgctg
    46441 ttccgaccga ctcaactttt gaccagtgag acctagctta aggttttctt caatactttg
    46501 gttttcaatt aagccaaagt tctggaagag gtaacccaat tcgtgacgga aaaaatcact
    46561 cgatttataa ttggccaagt ctttacctcg gtaaaaaatc gtcccatcat aaggttctaa
    46621 tttcccaatc atgttcatca aggttgtttt tccgctacca cttgaaccaa ttaaggcata
    46681 gacttttcca gcctcaaatg tcattgaaag attcgaaaat aactctcgtt ctccaaaaga
    46741 tttactcacc tgtttaagtt caatcatatt aacctccctt caaaacaaga atggacatct
    46801 tgttttcttt ctgcatttgg acatgtaact gtaaaagaga tagaccagta aagagtaaca
    46861 agactaagaa agcaactcct atctctacct gaagaaatac actcgcaaca aatcccagta
    46921 aaaacacacc cagttgagca aagagataag tgcgatggat ttctaagaac ctgagacctg
    46981 caatgcgttt gataaaaatg gcacgtctaa attcttcaaa gtagagccta ttcatagtgt
    47041 taaacaacaa gattgaagtt gcaatcccaa gcacagctcc tgctagcatt acccaacgtt
    47101 ccctctggat attatccaat aatgtgatgt agttgtggta acctgtttgc atttctgaga
    47161 cccaattttc aatgccttgt ctctggataa gctcctgggc atcagacaat tgattaaaga
    47221 gaacgtagtt ctgtactgcg tctatccaaa acaaaatgga ctgtggacca gttgattggg
    47281 gtgttataac aatgatgatt ggatctttca aaaactgctg gtaagaaata ggggtcgtat
    47341 tatacacaaa acgatcctga cctgattcta aataacctac cgtagcagtc atttgctgtc
    47401 gttcatcttg actagacatg cgactggtta agtcgtcttc aaaaacagat ttataatgtt
    47461 cttcctctga acggaggtgt tcaggcagca ataagacaaa ctcccctaca tcaaggtgat
    47521 tcatcttttg ctcaatagtt gtatctacag gaatgttttg acgctccaag tattgcggtg
    47581 tgacgataag gacattgcca ttcgggttgt aatcgtgcca ttctgtagag gttatcaagt
    47641 ttttggagga agccatgcca ttttgcaaag tacggtcaat taactggtgt ctagataaga
    47701 aagccttttg ttctgaaaca gccagatcca tcaattgata ccaagttctg agtttccttt
    47761 gagcttgttc atcaaaacca ggactcgttc cttcacggct gattgatagg gtaatcagtt
    47821 gcctttcctg actccaagcc tcttgtccaa tccgatgctg ttgccaggct tgggaatact
    47881 ttaagctact ccctattccc agcgttacaa taataatcgc taatagttga ccgattaaaa
    47941 tcaaactaat aattcctctg acaggcactt gcccttttat aatctgcatc aggtgtatct
    48001 tttttatccc aactgcgaag agttgagcga aaaacaggga gatcgacaac aagatgagat
    48061 tataactgag caagcctgct cctatggtca ttagggattg cgttggaagc gacagaattt
    48121 tttgcataag aatggcgagc acgccagcta aactgaaacc aacagctatc gctttcaaat
    48181 cctcaccaac tggtctaagg aaaatgaacc accgtttctc tcctgaaatg aggcgaatgc
    48241 ccgatgaccg taattggcta atttgactaa ttaaagtcag tgctacaaag gttaagatga
    48301 aaatcaatag actgattaac tgaaatccgt tactaaagat agccattaac gtagatagtt
    48361 tagatggaat tgtcaggtgc atgttagtca agccaagttg acttagctct tcccttagca
    48421 agtgaatatc taggtgtcca tcgaatacaa aatagtttgt ttcaacacta ctactttgag
    48481 catcttctag atttttttcc tgaagcccat caggcaactt tccgtcccca aaggtcgtat
    48541 aagaaaaaac tgtagtacct tctgagttag gatcttggtg ttgaatcgca ataaagctat
    48601 ctgtttcttc tgctagtttt tccaagcgtg tagcaacatg ctgaaaagtt gtttcagggg
    48661 aagaatcacg tacaacaacg ttggggtaat aatgggagac atatgtatca gtccaaatgg
    48721 taaataccca aacaaagaac aaactagcaa gcaggttgga tatgagtata aataattttt
    48781 tcatagtgca ttccttattc taaaacagag gccagaaata cccctgccct ctataaacta
    48841 acaagcttac taatatctat ctggtattgt tacaagctct catcagaata cctttctcta
    48901 aatagttgaa ttttaaagta atacgaaatc aatcagcctt cccaacatca agaccattgg
    48961 acttcttttg cgattgcact cgaatctcca attgtctatt cttctgaata aactgttggt
    49021 aaggaattgt attactaaac ataaaaacac ctagtaatac taatatagct aatttttgaa
    49081 ttccacgatt tttcttcatt cgtgaaaccc ctttcttttt ccttgttttt attttaatat
    49141 atatatatta ttcggtcaag catttttatg taatttttga ctttttttag tttattacca
    49201 taaagaatta tttatttctt ta
//
LOCUS       DAVMAH010000008        46806 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVMAH010000008 DAVMAH010000000
VERSION     DAVMAH010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.008"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(1..297)
                     /locus_tag="VYO94_000406"
     CDS             complement(1..297)
                     /locus_tag="VYO94_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759099.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            complement(281..2368)
                     /gene="pfbA"
                     /locus_tag="VYO94_000407"
     CDS             complement(281..2368)
                     /gene="pfbA"
                     /locus_tag="VYO94_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV1759100.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSLSVNSISSNGTIRSNSQLDNRTVESTVTS
                     TNENKSYKEDVISDRIIKKEFEDTALSVKDYGAVGDGIHDDRQAIQDAIDAAAQGLGG
                     GNVYFPEGTYLVKEIVFLKSHTHLELNEKATILNGINIKNHPSIVFMTGLFTDDGAQV
                     EWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLINSSGAFAIGNSNNVTIKNVTFKDS
                     YQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQIISKESIQIEPLTRKGFPYALNDD
                     GKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTLSTQNPSNIKILNNHFDNMMYAGVR
                     FTGFTDVLIKGNRFDKKVKGESVHYRESGAALVNAYSYKNTKDLLDLNKQVVIAENIF
                     NIADPKTKAIRVAKDSAEYLGKVSDITVTKNVINNNSKETEQPNIELLRVSDNLVVSE
                     NSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYISFIKSNANGKEPVIRDSDGNFNIV
                     TENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVIDSNQKNREFNSSKDNRQMNDKIDN
                     KQDNKTEEVNYKIVGDGRETENHINKSKEIVDVKQKLPKTGSNKIMELFLTVTGIGLL
                     LTLKGLKYYGKDK"
     gene            complement(3498..4724)
                     /locus_tag="VYO94_000408"
     CDS             complement(3498..4724)
                     /locus_tag="VYO94_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV1759101.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGANLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4767..5459)
                     /locus_tag="VYO94_000409"
     CDS             complement(4767..5459)
                     /locus_tag="VYO94_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1759102.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5632..7383)
                     /locus_tag="VYO94_000410"
     CDS             complement(5632..7383)
                     /locus_tag="VYO94_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759103.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7373..9118)
                     /locus_tag="VYO94_000411"
     CDS             complement(7373..9118)
                     /locus_tag="VYO94_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1759104.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALILVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9324..9701)
                     /locus_tag="VYO94_000412"
     CDS             complement(9324..9701)
                     /locus_tag="VYO94_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV1759105.1"
                     /translation="MKRLIDGKPTLLIKNGNIDPEACRSVGLSASDVSLKLRSQGIFQ
                     MKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDGVIQVDVLESIGRSEEWLLDNLSKQG
                     HDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9773..10229)
                     /locus_tag="VYO94_000413"
                     /pseudo
     CDS             complement(9773..10229)
                     /locus_tag="VYO94_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10363..11190
                     /gene="xth"
                     /locus_tag="VYO94_000414"
     CDS             10363..11190
                     /gene="xth"
                     /locus_tag="VYO94_000414"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV1759106.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11202..11345
                     /locus_tag="VYO94_000415"
     CDS             11202..11345
                     /locus_tag="VYO94_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1759107.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11456..11584
                     /locus_tag="VYO94_000416"
     CDS             11456..11584
                     /locus_tag="VYO94_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEV1759108.1"
                     /translation="MKANYPIYRPLTKRKFRVSDHYIYPHEFAVLDPNGYFLRFSE"
     regulatory      11967..12062
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12462..13043
                     /locus_tag="VYO94_000417"
     CDS             12462..13043
                     /locus_tag="VYO94_000417"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV1759109.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13043..14305
                     /locus_tag="VYO94_000418"
     CDS             13043..14305
                     /locus_tag="VYO94_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV1759110.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKIANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPIP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14356..14817)
                     /locus_tag="VYO94_000419"
     CDS             complement(14356..14817)
                     /locus_tag="VYO94_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEV1759111.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(14814..15578)
                     /locus_tag="VYO94_000420"
                     /pseudo
     CDS             complement(14814..15578)
                     /locus_tag="VYO94_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
     gene            complement(15759..16163)
                     /locus_tag="VYO94_000421"
     CDS             complement(15759..16163)
                     /locus_tag="VYO94_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV1759112.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKSGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(16233..17714)
                     /locus_tag="VYO94_000422"
     CDS             complement(16233..17714)
                     /locus_tag="VYO94_000422"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1759113.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVPPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVFRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGISLD"
     gene            complement(17733..18911)
                     /locus_tag="VYO94_000423"
     CDS             complement(17733..18911)
                     /locus_tag="VYO94_000423"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV1759114.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            19076..20083
                     /gene="galR"
                     /locus_tag="VYO94_000424"
     CDS             19076..20083
                     /gene="galR"
                     /locus_tag="VYO94_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV1759115.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20129..21166)
                     /locus_tag="VYO94_000425"
     CDS             complement(20129..21166)
                     /locus_tag="VYO94_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1759116.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAVTTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21167..21520)
                     /locus_tag="VYO94_000426"
     CDS             complement(21167..21520)
                     /locus_tag="VYO94_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1759117.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(21764..22654)
                     /locus_tag="VYO94_000427"
     CDS             complement(21764..22654)
                     /locus_tag="VYO94_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV1759118.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVVLENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            22787..23323
                     /locus_tag="VYO94_000428"
     CDS             22787..23323
                     /locus_tag="VYO94_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1759119.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(23489..24295)
                     /locus_tag="VYO94_000429"
     CDS             complement(23489..24295)
                     /locus_tag="VYO94_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV1759120.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(24640..26160)
                     /locus_tag="VYO94_000430"
     CDS             complement(24640..26160)
                     /locus_tag="VYO94_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV1759121.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELETVLNKLAGKITESQMSQLNYQVGVEGKPAEQVAKEFLQEQGLLKK"
     gene            complement(26153..26881)
                     /locus_tag="VYO94_000431"
     CDS             complement(26153..26881)
                     /locus_tag="VYO94_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759122.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(26896..27660)
                     /locus_tag="VYO94_000432"
     CDS             complement(26896..27660)
                     /locus_tag="VYO94_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV1759123.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(27664..28107)
                     /locus_tag="VYO94_000433"
     CDS             complement(27664..28107)
                     /locus_tag="VYO94_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1759124.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(28789..29085)
                     /locus_tag="VYO94_000434"
     CDS             complement(28789..29085)
                     /locus_tag="VYO94_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1759125.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(29107..30171)
                     /gene="pepA"
                     /locus_tag="VYO94_000435"
     CDS             complement(29107..30171)
                     /gene="pepA"
                     /locus_tag="VYO94_000435"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV1759126.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKFGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            30571..31287
                     /locus_tag="VYO94_000436"
     CDS             30571..31287
                     /locus_tag="VYO94_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV1759127.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLKENQIDAVLHYAGEIVVSEIVVSESIENPSKYFTANVA
                     GRNQVLKVLSEVGTQKIMFSSTASLYGNNCIDKPATEDTLIDPVNPYTETKLMGERMI
                     YWMANRYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGD
                     DYDTRDGSCIRDYIYVLDLA"
     gene            31710..32669
                     /locus_tag="VYO94_000437"
     CDS             31710..32669
                     /locus_tag="VYO94_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1759128.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKKRWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKCYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            32659..33615
                     /locus_tag="VYO94_000438"
     CDS             32659..33615
                     /locus_tag="VYO94_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV1759129.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYILLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            33612..34364
                     /locus_tag="VYO94_000439"
     CDS             33612..34364
                     /locus_tag="VYO94_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759130.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            34460..35425
                     /locus_tag="VYO94_000440"
     CDS             34460..35425
                     /locus_tag="VYO94_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1759131.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(35650..35892)
                     /gene="yidD"
                     /locus_tag="VYO94_000441"
     CDS             complement(35650..35892)
                     /gene="yidD"
                     /locus_tag="VYO94_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV1759132.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(35892..36614)
                     /locus_tag="VYO94_000442"
     CDS             complement(35892..36614)
                     /locus_tag="VYO94_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1759133.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(36601..37170)
                     /locus_tag="VYO94_000443"
     CDS             complement(36601..37170)
                     /locus_tag="VYO94_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV1759134.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37189..37917)
                     /locus_tag="VYO94_000444"
     CDS             complement(37189..37917)
                     /locus_tag="VYO94_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV1759135.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(37917..38657)
                     /gene="xerD"
                     /locus_tag="VYO94_000445"
     CDS             complement(37917..38657)
                     /gene="xerD"
                     /locus_tag="VYO94_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV1759136.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(38648..39109)
                     /locus_tag="VYO94_000446"
     CDS             complement(38648..39109)
                     /locus_tag="VYO94_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1759137.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39106..39627)
                     /locus_tag="VYO94_000447"
     CDS             complement(39106..39627)
                     /locus_tag="VYO94_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1759138.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(39603..40574)
                     /locus_tag="VYO94_000448"
     CDS             complement(39603..40574)
                     /locus_tag="VYO94_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV1759139.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(40571..41365)
                     /gene="racE"
                     /locus_tag="VYO94_000449"
     CDS             complement(40571..41365)
                     /gene="racE"
                     /locus_tag="VYO94_000449"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV1759140.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(41572..41820)
                     /locus_tag="VYO94_000450"
     CDS             complement(41572..41820)
                     /locus_tag="VYO94_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV1759141.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42076..43701)
                     /gene="treC"
                     /locus_tag="VYO94_000451"
     CDS             complement(42076..43701)
                     /gene="treC"
                     /locus_tag="VYO94_000451"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV1759142.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(43879..45846)
                     /gene="treP"
                     /locus_tag="VYO94_000452"
     CDS             complement(43879..45846)
                     /gene="treP"
                     /locus_tag="VYO94_000452"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV1759143.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFVYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            46031..46741
                     /gene="treR"
                     /locus_tag="VYO94_000453"
     CDS             46031..46741
                     /gene="treR"
                     /locus_tag="VYO94_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV1759144.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
BASE COUNT        13691 a        10659 c         8773 g        13683 t
ORIGIN      
        1 ttatttcatt ttattatact ctgttaattc atatgagttt aaaccgattt catctttaac
       61 ctcgagtaaa gcagtttcaa atatttgttt aagagttttt gattctttac aattaaccga
      121 caaactttct gataaaatat gtacaacttc tgagactgaa taacctatct cctctttaga
      181 attatataaa tctgtagctc caccaataat ccaaaaatac tgattttgtg aacctacaat
      241 atcctcattt tctacggaac ttccttgtat cgaacaaatt ttatttatct ttaccataat
      301 acttcaaccc ttttagtgtc aaaagtaaac caattcctgt cactgttaag aatagttcca
      361 taatcttgtt cgaaccagtc tttggtaatt tttgttttac atctactatt tctttagatt
      421 tattaatatg attttcagtt tctctgccat ctccaactat tttatagttt acttcttctg
      481 tcttattatc ttgtttattg tcgatcttgt cattcatttg tctattatct ttacttgagt
      541 taaactctct gttcttctgg ttactatcaa ttacattatt tgaattagat tgtttttcct
      601 ctttgttttt ttctttttcg tttttatcac ttaaattatt tgttacaatt ttgtaaagcc
      661 cattctccgt tacaatattg aaattaccat cgctatcacg tataacaggt tctttcccat
      721 ttgcattaga tttgatgaat gatatatact taccggataa attataaaat tggttattta
      781 aaacggttat tttacccttt gaatcctcaa taacaattcc ttctttaccc ccgaatatac
      841 tattctctga gactactaaa ttatcactaa ctcgtaataa ttcaatattt ggttgttctg
      901 tttccttaga attattatta attacatttt ttgttacagt aatatctgat acttttccta
      961 aatattctgc actatctttt gcaactcgta tcgcttttgt tttaggatcg gcaatattaa
     1021 atatattttc tgcgataacc acctgtttat ttaaatctaa taggtcttta gtgtttttat
     1081 agctataagc atttactaaa gctgctccgc tttctcgata atgtacactc tctcctttaa
     1141 ctttcttatc aaagcgattt cctttgatta atacatcagt gaatcctgta aaacgtacac
     1201 ctgcatacat catgttatca aaatgattat ttaaaatttt aatattagag gggttctgtg
     1261 tcgacaatgt ttgatagtgt gtgccaattg ctgttactaa ttccccagat ttatcacttt
     1321 tgccaaaata ggaattttga atagtcacat tttcagattt tttcccatca tcattcaagg
     1381 cataaggaaa accttttcta gttaatggtt caatctgaat gctctcctta cttatgattt
     1441 gcccatcctt catcgttttg ggtaaggctt gcccaagaaa acgagaatta tcaactaata
     1501 catttttcga acctgcaatt tgaatagcat gcccttgata actatccttg aatgttacat
     1561 tttttatagt tacgttattt gaattcccaa tagcaaatgc acctgaagaa tttataagtg
     1621 gtagattttt tgctttagtt ccttcttcat tcaaagcacc gttcatatca atcgtaccac
     1681 cagaataact aatatcttct gttgggcccc attctacttg cgcaccatca tccgtaaata
     1741 aacctgtcat aaaaacaatg gaagggtgat tcttaatatt tataccattt agaattgtag
     1801 ctttctcatt caattctaag tgtgtatgac tttttaaaaa aacaatttct tttactaaat
     1861 aagttccttc aggaaaatat acatttcctc cacctagccc ttgagctgca gcatctattg
     1921 catcttgaat tgcttgtcga tcatcatgaa tcccatcacc taccgcacca taatctttta
     1981 cacttaaagc agtatcttca aattcttttt tgataattct gtcacttata acatcttcct
     2041 tataactctt attttcatta gtagatgtta ctgtagattc aactgttctg ttgtctaatt
     2101 gtgaattgga acgaatagta ccattagagc tgatactatt aacacttaac gaattatcta
     2161 aatcattagt aattgcatta gaagactctt ttgtagccat cggtgaagaa ctagtaacaa
     2221 cttcatccga taaaatacct tggcttccca aaattgaaat tgccaatagt accgagcaag
     2281 tccccacctt taatttacga atactgaata cctcattagg aacaaaatat ttcatcagaa
     2341 cctccaattt ttttactatt tttaacaatt gattattact tttcttaaaa cagatagaat
     2401 gacaccgctg tcattatctt tatcatatat tttccaaatt gaattgtcaa ggaataacac
     2461 aagaaaatat taaaatttat actcttcgga aatctcttca aactaggtca gtgccgcctt
     2521 gccctaagtc taggttactg acttggtcag ttctatagta gactgaaact ataatagtac
     2581 acctctactt ctaaaacatt gttagaaatc gatttgactg tcccgatcga tttgtcctat
     2641 tcttatttca ttttactata tctacaacct caaagcaggg ttttgagcta tctatggcca
     2701 acttcctagt ttgctcttta gccttccatt caaaagtgat gctatctttc ttagcttgaa
     2761 tataaaatat cccatttact atatttaaat ttgttgatat gttgtaaatt ataaatgaaa
     2821 gaacaaatat cttgtcatac aagcatttgc cagggatatt tacctgaata tcgctcatat
     2881 ggcggattga aactaaaaca ctacaatata tttcttaaat agaccttcta taaaagctag
     2941 atttaacctc gataaaaata gatgcagtgc ttctaaaata ctggaatagg gcatataggt
     3001 aatcgtagac aagtgtttta tagattgtct cgcgggagat ctaatgatgt atagcaagca
     3061 tcactaaaca tatagaatat ttgtattatt ataatatcaa tatgctataa attctatcat
     3121 gcaaaagaat gactagaaca tgaaagacag gcacaaaact ttgaacaata ttctgaaaac
     3181 aaaaaaagac gcgagtttcc acaatctcac tcatggaaac tcacatcttt caaaaaatag
     3241 ggtgaattga aaactagaac aagacactag attttctaaa tgatgtctag taaggattct
     3301 aaatgctaca ccaaattgct cacatcttat ttcaaaccac gggactccca caagaaagga
     3361 aaatcctata aaaattctct ctctgaggag aaaggagcct caactacagg tgtaaactat
     3421 tatcaattga aaacaacagt ttttacactc aattagactt tttagggaca ggatcacttt
     3481 cgcttgactg tagtttgtca tttttttgat aaagttagca ctttttcaga aactgttttg
     3541 aaagtctcaa tgatatagtc tacttcttca tcgcttaatt tagtatgaag agggagggta
     3601 atttcattct caaagaaggc ataggcctta ggatagttcg tcatatcaaa tccaagattc
     3661 ttataggctg tcaagagagg aagcggtttg tagtgaacat tacttgcaat tcctgcttta
     3721 gccaattctt ggatgatgag gttgcgttct tctaggtttg ctccttctac acgggtgatg
     3781 tagaggtggc gtgaagattc gacagtttca gtcttgtgtg ccaaaggatg gatgcgagaa
     3841 cctgcaaaac cactatcata gcggtccaca atgtccttac ggcgttgcaa caaacttgga
     3901 tagcggtcca attgtaccaa accaagtgaa gccatgatat cggtcatgtt gcacttatag
     3961 gctggtgtaa cgatatcgta ttcccatgac cccaattgca tcttggcaag agcatcctta
     4021 gtttgcccgt gaagggaaag gatttggaat tccttgtaca tctcttcgtc atcaatcact
     4081 ggattggctt tccaagtcgc acttccacct tctgccgttg taaagttctt aacggcatgg
     4141 aatgagaagg aagtaaagtc agcgatagaa ccagaaggtt gtcctttata agtagatccc
     4201 aaagcgtggg cactatcaga gacaatgaca atacggttaa aggccttttg ccacttgctt
     4261 gaagcggtaa agaagtcacg ttttttctcc acgacttgga acaaacggtc ataatcgcaa
     4321 acaatccctg cgagctctac tgggataatc accttagttt tctcagtgat agcttgctca
     4381 agcaggtcat agtccatctc aaacgtatct gcttggatat ccaccatgac aggggttgct
     4441 cccacgtgcg taatgacact acatgaagcc gtataggtca tggctggaac gatgacttca
     4501 tcaccaggtc ccacttccaa aacgcgtaaa atcaactcca gagcagctgt cgcagagttg
     4561 agacaaacag tcttaggtgt ctgtgtgtaa agagacaagc ggcgctccag ttcttttgtt
     4621 ttaggacctg ttgtgatcca accagaacgc agggtatccg ctacttcagc aatttctgct
     4681 tctgtgatat caggcggtga aaatggaata ttgtaatttg gcattgattt gctcctttta
     4741 tctgtactca ttttcttatg actactttat tttagtacct caaacacggt ttgaaacatg
     4801 attttgatgt ccccaaagaa actaaactct cggagatagg cgaggttata gcgcatcttt
     4861 tcaggaagaa catgctccac ataggcctga tcaactgaca gacctttctc cgtcatttga
     4921 ctgatgatgg tgtcctcatc cttgtagttg atgctggctg gagaggtaat tcctgcttgc
     4981 aagagcaagg ttgccatcat ttcagggcta tactgctctg tataacgtgg cacttcaggt
     5041 cgtgtaccga caaaggacat ctcaccttta aggacattga ccaactgagg cagttcgtcc
     5101 aaacggacac gtcggatgaa atttccaacc ttggtaatac ggctatcgtt agcagaagtc
     5161 accagacttc cttttttatc cgcatccgtc accatggtac ggaacttcca aatcttgaac
     5221 cgacggttgt actgggtcac acgctcttgc ttgtaaatca ctggcccctt gctatccaac
     5281 ttgatccaaa tgctcaagat gagaaagatg ggagaggtca gaaccagtaa gaccaaggcc
     5341 aaaacccagt ccaagcaacg cttgaaaatc agcgaaccct tccttttaga gacaagctgg
     5401 tagtaagact caacctcgct tgatttcatt tccacaggca agtcttccca tttcagcatg
     5461 ctgttctcct ttgtttttat tatactattt gtcaacattt ttcattatac cacaaaatgg
     5521 aaaaggcggt gaaagaaatc tgtaatttga aggatttcct tctagtactc aatgaaaatc
     5581 aaagtacagc tttgagattg cagataaagc tgacatggtt taaagagatt ttcaaagagt
     5641 ataggccatg gcccctgcct gcaaactata catcttgtga taggttcctc ccagagtcaa
     5701 gagttcctca tgggttccac tctcgataat gcgtccctta tccaagacat agatgcagtt
     5761 ggcgtcttga atagtagaaa ggcggtgagc gatagcaata gttgttcggc cctgtctcat
     5821 cttcgccaga gaagcttgaa ccaagctttc tgtttcagag tcaatattgg ctgtcgcttc
     5881 atccaaaatc aggattttag gctggctggc gactgttcta gcaaaggcaa gaagctggcg
     5941 ttgcccagta gagaagctcg aaccacgctc ggaaacaggg gagtcgtacc cctgaggaag
     6001 ttcttgaata aaggaatctg catccacaaa ggctgccgca gcctgaacct gctcatcact
     6061 gatttcttgg tacatggcga tattggactt aatagttcca tgatagagga agggttcctg
     6121 taaaaccaaa ccgatgtttt ttctcagctc ttcttgactg aaatccctga tatccacatc
     6181 atccaagaga actctccctg actggaattc ataaaagcgc atgaggacat tgataataga
     6241 cgatttccct gaacctgtat gacctacaaa ggcaatggtt tcacccttat taacagagaa
     6301 agaaatgtca tccagaatcg gatgtttacc gtcatacgag aaacacacat gttcaaaacg
     6361 gatattgcct tctttgactt tggcttgccc attttcttga aggggctcat aggtcctctc
     6421 atcgattaag gcaaagacac ggcctgcaga aaccatagac gtttgcagtg ttgaaaagtt
     6481 ttgcgtcacc tcaatcaaag ggtcaaagag gcggttgatg tactggataa aagcatacat
     6541 ggtcccggcc gttatcccga tagaaagacc acgatagcca aaataggtca tcaagacagc
     6601 ataacctaga agtttcaaca aactcatggc aggtctcaaa aagagggcat ccaaggctac
     6661 agaacggttg gcataggcca agtgctcttg gttgatttca tcaaattctg cctgcaggcg
     6721 cttctcttga ttaaaagcct gaataatcct gattccctcg atattctctg ccagcttact
     6781 attgatatct gacaagagac ttctggtttt ctcgatgatt ttcactgact tttttcgata
     6841 gagattgacc aaaaggaaaa tcaaaggaag aaagagcaag actaaagccg tcaaacgaaa
     6901 atccagcacc aacatggtat aaagggttgt cagaaagata aaaactgctg agataaagct
     6961 ggataaaatc ccagaaaaca tatcactaat cgtctcggta tcgttggtca aacgagaaac
     7021 gatagaacct gctggcgtct tgtcaaagta agacatgccc agtttctcca tattggcaaa
     7081 ggcatctcga cgaatatccc taacaatact gtaagacacg cgcgcaaaga gaagattgcc
     7141 tacatactga actacagttt gtaggatgta gagaccatag tagaccagca aaacggtaac
     7201 ggctagttgg ttaagattgc tgagatactg gtcgataaag tgggaagcca cgaggggtat
     7261 gacactttta atgaccgtcg tcgctaggag aaaactgagt gccaaaaagg tcaggagtcc
     7321 ataaggcttg agataagaca tcaagcgctt caatacagcc cattgttctt gtttattctg
     7381 catcttcttc tcctttcatt tccaactgct gagactggta ggtttgggca taccagccat
     7441 ccatcgctag caagtcttcg tgcctgcctc gttcgataat ttgaccattt tgtagaacta
     7501 aaataaaatc tgcatggaca actgcactca ggcgatgggc agtgataatg gttgtcttgt
     7561 cctttcgcgt ctccttgagg ttgtcgataa tcgcatactc tgtcttggca tctacggcgg
     7621 ataaggaatc atccaaaatc aagatatcag ggtctaaaat catagcccga ctcatagcca
     7681 accgttgctt ttgaccacca gaaagactga ctcctttttc accaatcagc gtatcaaatc
     7741 cttgaggcat gtctacaata tcttggtaaa cccgggctag cttagtagct tcctcgaccg
     7801 ctgaaagggg caagttagga ttgccaaagc ggatattgtc taggattgaa gtcgcaaaaa
     7861 gaaactggtc ctgaggaaca tagcccatga gactgcgaag gtctgtcaga cgatagtccc
     7921 gaatatcgtg accgtttaga taaatggcac ccttatccac atcgtattca cgcaagagga
     7981 gcttgattaa ggacgttttc ccagagcctg tttgcccaac caagcccagt gtttgccctt
     8041 ttgccaaact aaagtgaata tccgtcagtg tttcctcatt ttcaaaagca aagctgtcaa
     8101 tggcatactc caaacgccca ttttcaatac catccagagg aaactcaggg tcttgtacag
     8161 gagattcctg agacaaaaga ttttcaatcc gctggtaaga aaccttccct cgctgagtag
     8221 tattaaagag gaaaccgatg gccagaagag gccagaccag catatccaaa tagctgataa
     8281 aggtgactag attcccaact gtaatctgcc cttcctgaac catcaaggag ccaaccaaaa
     8341 gcgttaaaac ataggacgaa ccaacaaaca agagaaccat agggtcaaag agactatcat
     8401 atttcatggt ttgcaggttc ttttggaagg ttaattcatt gactgcctga aaagacttca
     8461 actcgtctgc ctgataaccg aaagacttgg tcactttgat acctgatacg gactcctgta
     8521 ccttgttatt gagttcagaa aaagcagctt gggattcgcc aaaggcctta tgagtctttc
     8581 tccctaggcg actagtcgta taggccatga aaggtagggg gagaatggca acaagagtca
     8641 tctgccatga gatgctaaag agcatggtca acaaagtcac cagagccgtg atagaggcat
     8701 ccaccgcaga catgacaccg ccacctgcta aacgagtcaa ggcattgata tcattggttg
     8761 cgtgtgccat cagatcaccc gtccgatagg tttgataaaa ggctgacgac atttttgtga
     8821 aatgcttaaa caagcgagac cgcatgatct gtcccaagca ataagaggtc ccaaggatat
     8881 acatacgcca cacatagcgc aaatagtaca taccaaaggc tgcaagtagc aagtaaaata
     8941 ggctaagaag gaggtcctgc tgggttaatt gccccgatgt gatggcatca atgacccgcc
     9001 ccataaccat aggaggaatg agattgagga cggaaaccaa gatcagggcc acaattccga
     9061 ctagataacg gcgtttttct aacttgaaaa accaccaaag tttttgaata atggacataa
     9121 aatccctttc tgattgcaaa tggaaacctg aggccaatac tcaatgaaaa tcaaagagca
     9181 aactaggaaa ctagccgcag gctgctcaaa gcactgcttt gaggttgtag atagaactga
     9241 cgaagtcagt aacctacata cggcaaggcg acgttgacgc ggtttgaaga gattttcgaa
     9301 gagtacaaga ccccaggttt ttcttattca taagttacga ctgtaacagc acccttgtca
     9361 tattcagcaa taaagatatt ggctacattg tcatgccctt gtttactgag gttatcaagc
     9421 aaccactctt cgctacgacc aatcgattcc aagacatcta cttgaatcac accgtcagtc
     9481 acaactggat acttaggatt ttcatctccc atttgcacaa cgatgagttg cccattttgc
     9541 tcttgcacag ctcgtttgac ttgcttcatc tggaaaatcc cttggctacg aagtttgagg
     9601 gatacatccg atgcagacaa accaactgaa cgacaggctt ctgggtcaat attcccattt
     9661 ttgataagga gagttggctt accatcaatc aaacgtttca caaagtgaac attgttgttg
     9721 agctatttga gagtcaagac cagtttgatt aaaatttcga tataattaag tgtcatttgt
     9781 tcacatccac cagttcaatt gcgtctgtct tatacaattc gactttctct aacaggtact
     9841 tgtctggctc acttccgttt agggcacgat aatagcgatc tcccaccttg ataagtgcgc
     9901 catctgtgtt tgtggaagta ttaacataga cttctgactt gtctactccc aaatctttgg
     9961 aaacaacctc gatgaaatga agtgaagttt gaaatttatt gttagaaact tgattgtttt
    10021 gataagtcgt gatgctgacc aaaagcagag ctaaataagg ccagatctga aatcatgacc
    10081 aactcacgaa attcgcttcc ctttttatta tggtatgcct tgaaagcaaa aaaaactgtc
    10141 acagctaata gaacaatccc aaagccaacc atgataccat tttgctgacc gatttggctg
    10201 agtacatagt cataagagta gaatttcatg tattttcact ccctttcata aaatcattct
    10261 taattataaa cgaaagagag taatttttca aaccatacgt tggggaaata gatctttttt
    10321 tggtataata aaatctataa tctgaatgaa aaaggtaact ttatgaaact tatctcatgg
    10381 aatattgatt ccctaaacgc tgccctaact agtgactcag ctcgtgccaa attgtcccaa
    10441 gaagtcctac aaaccttggt cgctgaaaat gctgatatca ttgctatcca agaaaccaag
    10501 ctttctgcca aaggacctac aaagaaacac gtggaaattt tagaagaact cttcccaggc
    10561 tacgaaaaca cgtggcgctc ttcccaagag cctgcccgta aaggctatgc tggaaccatg
    10621 ttcctttata agaaagaact tacacctact atcagcttcc cagaaatcgg tgccccttct
    10681 accatggact tggaaggtcg tatcatcact ctagaatttg atgcattttt cgtaacccaa
    10741 gtttacactc caaacgctgg tgacggtctc aaacgcttgg aagaacgcca agtctgggat
    10801 gccaaatatg ctgagtattt ggctgaacta gacaaagaaa aaccagtcct tgcgaccggt
    10861 gactacaacg tagcccacaa tgaaatcgac cttgcaaatc ctgctagcaa ccgccgttca
    10921 cctggattta ctgacgagga acgtgctgga tttaccaacc ttttggcaac tggatttaca
    10981 gacaccttcc gccatgttca tggcgatgtt cctgaacgct acacttggtg ggcacaacgc
    11041 agcaaaactt ctaaaatcaa caatacaggc tggagaatcg actactggct cacaagtaac
    11101 cgtatcgctg acaaggtcac taaatctgat atgattgact caggtgctcg ccaagaccat
    11161 acaccgattg tcttggaaat tgacttgtaa ggattttcta tatggactac aatgcggtca
    11221 ttcccgagtt gcttgtatcg aatatcgaac agtcccggtc cttctactgt ggtttactgg
    11281 gttttaggat tgaataccaa cgtccagaag aaaactttct ctttctcttg aagagtgtca
    11341 actaatgtta gaggagggaa caaaggatca actagctgaa ctgacctatc cctttggtcg
    11401 tggagtcaat ctctcctttg gcataaagga tgtttcaaaa ctctattaaa gagtgatgaa
    11461 ggcaaactat cctatttatc gtcccttgac caagagaaag tttcgtgtca gtgatcacta
    11521 tatctatcct catgaatttg cagttttgga tccaaatggc tattttttaa gatttagcga
    11581 gtagaataat aaaaattggg aaaagtcttt aaagttagaa aaaggcatat tgtcaggtgt
    11641 ctaaaaactt gatagtatgc cttttatgat ggaaaaatct tctaatactc ttcgaaaatc
    11701 tcttcaagcc acatcaacgt cgccttaccg taggtatatg atactgactc tgtcaattct
    11761 atccacaacc tcaaaacagt gatttgaggt tgtggatagc ttcctagttt gctctttgat
    11821 tttcatttag tataaatgtt agcttacaat ggagtttttg ttcaccctct cttctgtttg
    11881 ttcgtttttt aaaccaaaac actaacaaaa tagttgattt ctaaagttat ttagtgtaaa
    11941 ataaaaacat tggctcaagc ctatttaaaa ttgaatatcg ttttacttgt ttatgtcgtg
    12001 aattggcacg acgtttctac aaggtgccgg aacacctaac aataagtaag tcagcagtga
    12061 gatatggccg tttttgccat gtctatttag gggacttact tagagattaa gtaggtcttt
    12121 tttgaatatt tttaatattt cccttaatta gtgcggacgg gaggtgaaat tatcctgtga
    12181 ataatttcag gaatccaggg aatttcatcc ctaatttttg agcccctagc tctttcattt
    12241 ctaggcttag gctaaaatag ttccccgaac tattttactc tcaaaaatcc cgtcatagac
    12301 aataacaaga ttattgtcta tgataccact acaacgggaa atatttgata agactattac
    12361 gagcgaagcg agtcttatca aatatatagt attagcaaaa gggatcacta tagaaacatt
    12421 taaacaacaa gtaaattagc ttttagactt taggaggtct tatgaaatta ttagaagagc
    12481 gcatcctcaa ggatgggcat atcttgggtg ataacatcct caaggtagat tcctttttaa
    12541 cccaccaagt tgactttagc ttgatgcgag agattggtaa ggtttttgcg gaaaaatttg
    12601 ctgctactgg cattaccaag gtcgtaacca ttgaagcgtc gggtattgcc ccagccgttt
    12661 ttacagctga agccttaaac gttcccatga ttttcgccaa aaaagctaag aacatcacca
    12721 tgaacgaagg catcttaact gctcaagtct actcctttac caagcaggtg accagcactg
    12781 tttctatcgc tggaaaattc ctctcaccag aggacaaggt tttgattatc gacgatttcc
    12841 ttgctaatgg ccaagctgct aaaggcttga ttcaaatcat cgaacaggcc ggtgccacag
    12901 tccaagctat cggtatcgtg attgagaaat ccttccaaga tggtcgtgat ttgcttgaaa
    12961 aagcaggcta ccctgtccta tcacttgctc gcttggatcg ttttgaaaat ggtcaggtcg
    13021 tatttaagga ggcagatctc taatgcaaac tcaagaaaaa cactcgcaag cagccgttct
    13081 gggcttgcag cacttactag ccatgtactc aggatctatc ctggttccca tcatgattgc
    13141 gacagccctt ggctattcag ctgagcagtt gacctacctg atttctacag atatcttcat
    13201 gtgtggggtg gcaaccttcc tccaactcca actcaacaaa tactttggga ttggactccc
    13261 agtcgttctt ggagttgcat tccagtcggt cgctcccttg attatgattg ggcaaagcca
    13321 tggtagtggc gctatgtttg gtgcccttat cgcatctggg atttacgtgg ttcttgtttc
    13381 aggcatcttc tcaaaaatag ccaatctctt cccatctatc gtaacaggat ctgttattac
    13441 cacgattggt ttaaccttga tccctgtcgc tattggaaat atgggaaata acgttccaga
    13501 gccaactggt caaagtctct tgcttgcagc tattactgtt ctgattatcc tcttgatcaa
    13561 catctttacc aaaggattta tcaagtctat ctctattttg attggtctgg ttgttggaac
    13621 tgccattgct gctactatgg gcttggtgga cttctctcct gttgcggtag ctccacttgt
    13681 ccatgtccca attccactct actttgggat gccaaccttt gaaatctcat ctattgtcat
    13741 gatgtgtatt atcgcaacgg tgtctatggt tgagtcaact ggtgtttatc tagccttgtc
    13801 tgatatcaca aaagatccaa tcgacagcac gcgccttcgc aacggttacc gcgcagaagg
    13861 tttggccgta cttctcggag gaatctttaa caccttccct tacaccggat tttcacaaaa
    13921 cgttggtttg gttaaattgt caggcatcaa aaaacgccta ccaatctact acgcagctgg
    13981 tttcctggtt ctccttggac tgcttcctaa gtttggtgcc cttgcccaaa tcattccaag
    14041 ctccgtcctc ggcggtgcca tgctggtgat gtttggtttt gtatctattc aagggatgca
    14101 aatcctcgcc cgagttgact ttgctaacaa tgaacacaac ttccttatcg cagctgtttc
    14161 aatcgctgca ggtgtcggtc tcaacaacag taatctcttt gtcagcatgc cgacagcctt
    14221 ccaaatgttc ttctcaaacg gaatcgtcgt agccagccta ctcgccattg tcctcaatgc
    14281 cgtattaaat cataaaaaga aataagaaaa agaggtgcga gcctcttttt tgtgtgacaa
    14341 aataaaaaca tctacctatt catatatgct agtgtcatag tcctgaaaat catctgcatc
    14401 aagaacaatt tcacaactct tatacttttc tcttacaagt cgttcggctt catctggatt
    14461 ttcagcctct atacttacta aacgtgataa agtttctgta atttctactg tatacttttt
    14521 cagttttaga ttgctttcca ataattcacc tattaacaat aatctatgat aggagctatg
    14581 tagccactct ggcaatttat ctcctacttc ccacccatat ttttccttca tcaaagctag
    14641 ttgtttttcg tcaccaaatt tcatattttc agataaccat ctcacacaat cgggatctga
    14701 taaggtacag acgattaaac ttaggttatc gtaacggctt tcagtttcat aatcaggcca
    14761 gatgactttt aagaaatcat acacctcttc tgatgcaaca agttgtttcg ttttcataat
    14821 ttccgatact ttcctctacc tttaaattct attatttctt tgtctcttaa tatttgaagc
    14881 tgttgcctaa tcttttcttt gatatgattg ttcttaacaa agatattttt taggtcactt
    14941 tcaaaacgat acatatcttc aagggtaaat tctgaaccct ctatcttatc tatacaattt
    15001 agaatttcta ttgtccaacc tcttgatgac agagagctct tccttaaaaa taaaccttgc
    15061 ttaaattctt ttgtaacttt ttctggatct ctaacttgtc catcttgcac aagaaatatc
    15121 cttcctttag aaggtacttg tgataaatca atgttacaac caatccaacc tgctcgtcta
    15181 gcagttggtg caagtggttt tctttgaata attgatttcg gtgtaacaaa ttgcttcgga
    15241 aggacaagaa agttatttac ctcaaaattt tttgtgtaag tttaaaaaaa gaaattagga
    15301 ttattatctg cctgcacacg cttcatcatc gttgcataag caccatcatt gattgttgat
    15361 gaaaaatttc cttttttgct ctttagttca aactcctcac tacaatgatt acagtaaaaa
    15421 tctgctacag gccgattatt ttcaaaatga tttaagggat tgttcccaca attagggcaa
    15481 taagactgac gataaaccca atcctccgtt aagatacgtg ccttttggct attactttta
    15541 taggtttcta ctaattctaa attaaagtgt aattccattt aaaaattcct cactaatatg
    15601 agaactcact cgatataagc aattaaaatc tactataact agtataccac atatatgtac
    15661 ctattacatt tgtatttcat cactctcttt tatatttcct tctaacatat ctcataaatt
    15721 aaaaatgagt gagataaatt tatcccactc acctttcttt atatacttac ccgtctttcc
    15781 tcagaccttt ggcctgtgac aaacatggta aaggttgctt tacagacatt tctgccctct
    15841 tgattggtga tatccacatc catcacacag gttgtacgac cttgatggac acattctcct
    15901 ttaatggtca atacatcgtc gagttttcct gacttaaggt agttgataga ggattggagt
    15961 gtcaccccat caagtcccag cgagataacc accaaaccac tgatttggtc acatagcgtg
    16021 aatagatagc caccatgggc attgccatag tagttgagcg acgagttcac tactttggtc
    16081 gtcaccacaa cgtgaccatc tctcattttt tcaatttcgt aattttcaaa ggcagatata
    16141 gcgtcaaaat gaaagtcttt catcgtttcc tcctgatatt tcaaacgaca ctatgatact
    16201 actttttata ggactgtgca aggagaaagc tcctagtcta gtgaaattcc gacctgttcc
    16261 acaaagcgca taaaggctgt ctgcccttgt tctgtctgct tgtagactcc tgcatcctca
    16321 agtacacgca caaagatagc acccacagag tccttgacga ttgcaagggc tttttcttta
    16381 tccgttaggt ctggatgttg ggatttgagt tggtctgccc actcctgatg ataatcggca
    16441 actgtaacag cttctcctac aagatagcta gcgacttgct ccacttcttc tttcagacgt
    16501 ggtggcaaga ttgccaagcc catgacctca atcaagccga tattttcctt cttgatatgt
    16561 tggacatcct tgtggggatg atagatgcca tcaggatgct ctgctgaagt ctgattgtct
    16621 cgaaagacca agtccaactc aaactgtcca tcacgcttac gcgctattgg tgtgatggtg
    16681 tgatgcggtg tcccgtctgt ctctgctaaa atctgcacac tagaatctga atactgacgc
    16741 cattcctgga aaatcttatc agctaagtta atcaaatcct ctttggaatc cgaagtcaag
    16801 cgtaggacag acattggcca cttgataatt ccagccttga cctgctcaaa accagcaaat
    16861 cggaaggtct tttgcaaggg agccaattcc ataggaaata cgtgacggcc tccctgataa
    16921 tgatcgtgag ttagaataga gccccccaca atcggcaggt cggcattaga tccagcaaaa
    16981 tatcctggaa actgctctac gatagccaac agacgttcaa aactctgacg actaatggcc
    17041 atgggacgat gctggccatc taaaaagata caatgctcat taaagtaagc atagggcgaa
    17101 tactggaacc cccattcctg accaaccatt tcaaaacgga taatccggtg gttgctgcga
    17161 gctgggtggt tgacccgacc atggtaaccc tcattctcta aacaaagttg acactgagga
    17221 taattactag cttgcaccaa tttggctacc gcaatctctt tcggatcctt ttcaggctta
    17281 gagagattga tggtaatttc aagttctcca taatcagatg gaacacgata agcgatattt
    17341 ttagcaatgg ccttgagttt gatgtagtca tttttctgac tgagttgata aaaatcctct
    17401 atcgcttgct caggagagta ggcataggct tcccagaagt cacgattgac ctgactcgga
    17461 caaggaggca ccaagtccat cagttcagta ccaaggattt cacgcgcagt ctgactatcc
    17521 tcaatcgtct ctaatcgaac ggcttcctca actagctggt ccttgaggtc aatcaattta
    17581 tccagattgg tctcaacttc caaaacacct tctcccactc gtgccaaaac acggttggtc
    17641 aggtagattc gatccatttc ctcaaatgaa ctttcagaaa tgacatgtgt tacaaattta
    17701 tctactaaga tcactataga gcctcctttt gactagtcaa ggacgcgagt gccacctgca
    17761 acttcagcga tatagaagct tggagcgtat ccaactactt cctcgtagtg tttgcctaca
    17821 gcttccttaa aggcctcaac agtatctttt tgaaccaagg caatggcaca gccaccaaaa
    17881 ccagcccctg tcatacgagc accgagaact ccttcttgtg cccaagctgt gtgaacaaga
    17941 gtatccaatt ccaaaccagt tacttcataa tcatgctcca gagaaacgtg tgacgcattc
    18001 atcaaacgac caaatgtttc caaatcacct gcttgaaggg ctgcttgagc tttaagggta
    18061 cgttggtttt caagcacagc atggcgagca cgtttcaaac gattttcatc tttaatcaaa
    18121 tagctatatt ggtcaacggc ccactcgtcc aattcaccca gggtctgaat atccaaggca
    18181 acttgcaatt cttccactgc tttttcacac tcagcacgac gttcattgta tttagagtcc
    18241 gccaattcac ggcgtttgtt ggtgttcatg ataacaacga cattgtcctt caaatcaagt
    18301 ggcaccaaat catactctaa ggtgttggta tcaaggtaaa tagcacgttg atcggccccc
    18361 ataccaatag caaactggtc catgatacca gagttgactc cgataaagtt gttttctgtt
    18421 tgttttccga ttttaaccaa atcgagacgc tctaatttta aatcaaagag atgctctgcc
    18481 acgactcctg tcaagagctc caaggatgct gaagaagaca agccagcacc atttgggata
    18541 ttcccataaa cataaaaatc aaaacctttg tcaatcacgt gcccagcttc ttgcaagaaa
    18601 tgaaggacac cttttggata attggtccag ttgtgctctt tttcaaactt gaggtcagcg
    18661 agaggcactt cgataatgcc cttgtcctca aagttagctg agtagaaacg caagacttgg
    18721 tcgtcacgct tacgagctgc accgtaagtt cccaaggaaa tagcagcagg aaaaacgtgc
    18781 ccaccgttgt agtctgtgtg ttcaccaatc aaattaatac ggcctggtga aaagaaggtt
    18841 tggtctgctt cttgaccaaa aacagcaaga aagtctttgc gaaggacttc agtagtaaga
    18901 tgttgtgcca tatgaattct cctttgactg tccgttaagc catcttaacg tgtaatcgtt
    18961 ttctttctat tgtatccaag aaatttccca aggtcaatcc tttttactaa aattttacta
    19021 aaatatcagt aaaaagaaga aaaatatgat atactaacct aatcaaggag gatttatggc
    19081 taccttaaaa gacattgcac agctagcctc tgtctcaatc gcgaccgtat cccgtgtcct
    19141 caaccgcgac cagagcctat ctgttacaga agaaaccaga caccgtattt taaccgttgc
    19201 tgaagagtta ggctacacca aacacctcaa gacaggcgag tcccacaagc ccaagcaaaa
    19261 gattgccatt atccaatggg tcagcgaaca aggggagcta gacgacctct actactacca
    19321 gattcgccta ggaatagaaa aaagagccca agagttggac tacgatatct tgcgctattt
    19381 taatgaccat ccttttacct taagcgagga agtgattggg attctctgca tcggaaaatt
    19441 tagccgagct cagatttctg cctttgaaga ataccaaaag cctcttgtat ttctagacag
    19501 cgatacactt tccctgggac atacctgtat tatcacggat ttttacactg ctatgaaaca
    19561 ggttgtcgat tatttcctca gtcaagggat ggaccgcatc gggattctaa cagggcttga
    19621 ggaaacaaca gaccaagaag aaatcattca ggacaagcgt ctagaaaact tcaaaaacta
    19681 cagtcaagcg aggggaatct atcatgatga actggtcttt caaggaagat ttactgccca
    19741 gtctggctat gacttaatga aggaggccat tcagagcttg ggagaccaac ttccgccagc
    19801 atttttcgca gccagcgata gtttagctat cggtgccctc cgtgccctcc aagaagctgg
    19861 aatcagcctg ccagatcgcg tcagcctcat ttcattcaac gacaccagtc tgaccaagca
    19921 ggtttatcct cccctctcca gcatcacagt ctatactgaa gaaatggggc gagcaggtat
    19981 ggatattctt aacaaggaag tcctccacgg tcggaaaatc cctagcctga ccatgctggg
    20041 aaccagactg acattaagag aaagtaccct aaatcaagaa taggataaca taaaaaacga
    20101 atagagttct aaaactccta ttcgtttttt attcgattac aatcatagac ttaatggtct
    20161 tacgttcatc catatcttta taggcctggt cgatatcttc cagtttataa cttgaagtaa
    20221 agacgcgacc tggattgata tcaccatcaa ggacggcttt tagtaaaaat tgcttatcgt
    20281 atgttgtagc agaagctgcc ccacctgcta cagagatatt ttgcataaat gtcgaaccaa
    20341 gagcacgatt attatagtgt gggactccta caaagcccat acgccctcca ttatgaagaa
    20401 cacctagcgc ctgttctata gcagcctccg taccaacaca ttcaagtgct gcgtctgctc
    20461 ctccaccgag gatttcacgc accttggtaa ttccttcttg accacgttct gcaacaacag
    20521 ctgtcgcacc tgactccata gccatctttt gacggtcttc atgacggctc ataaggataa
    20581 tttgtgatgc tccacgcatc ttagccgcga tgacagcaca ttgaccaaca gccccatcac
    20641 cgataacaac aaccttgtcc cctttttgaa catttgcaac acgcgccgca tgatagcctg
    20701 tcggcatgac atctgcaaga gtcaaaaggg actggagcat cccttctgta tagtcagaag
    20761 gttgaccagg gattttaacc agcgcccagt ttgcatagtg gaagcgaata tattctgcct
    20821 gaaaatcacc ccccaaatta ttgccaatat gattgtcgca agaaccgtca aatccagcaa
    20881 gacaggcatc acactcacca catccatgtg taaaagggac aatcacaaaa tcacctggtt
    20941 tcaccgtcgt aacggcttcc ccagcttctt caacaatccc aatcgcttcg tgtccactat
    21001 ttttgtgtcc agctttcgtt tctggattac ggtacctcca taaatctgaa ccacaaacgc
    21061 acgcacgaac cacacgaata atcacatcat ccgcttctat tatttgcgga cgttcaatgc
    21121 tagcaagtcc aacctgacct gcctttgtat atactgctga tttcatttaa aattttcctt
    21181 ccttataaag tttaattttg agatttaaac gatttaaagc tgtctgtagc tgagacaagc
    21241 gctcctctaa tttttgcttt tcctcttcta aaataccaag cctctcctct ctcgtttcat
    21301 ctcccttttg gtagagcgac atatagtcaa ctaaactatc tacagagaca cccgccgaac
    21361 gaaaacactt aataaattcc agcgcttcga tatcctgatc ttgaaaatca cgaatcccag
    21421 tagcagtacg agtaatcggt ggcacaagac caacccgttc ataataccga atcgtatccg
    21481 ctgaaattcc caacaaatca ctggcagatt taatattcac acgctaacct cctctcattt
    21541 cattcactga attcacgcta ttctaactca cttatcttat tatataactt tgagttgact
    21601 ccaagtcaag cattttgtat ctaatcgaaa aatttttatc attaacaatc atatatatgg
    21661 agtttataca atgctcttct cttaccaatt tttgaaatat ttaaataata aagaaattac
    21721 tctattccaa ataagatagt acccaagtat ttttcacttt tttctaatgt tggtgctcat
    21781 aactccgttc caagtcacac acctttcgct tatgggtttg gtgagtttct aggtcagcat
    21841 caatttcaat ggtaatattt tgaaaaccac aatcttttag gaaaattcga atagactctt
    21901 tacaagtttc catatgttcc atttctttta gacaaacatg gacaatggca tttttttcca
    21961 aagcatccat agtccagaga ttaagctgat taaggctggc cacattgtcc aatcgctcca
    22021 ggccactctt tacttgcttg atatcaagac cttctggcac agcatccaag aaaatcttga
    22081 gtgtagacca aaaacgtgga agggcttttg aaagaataaa gaaagaaatg acaagggaca
    22141 aaagaggatc taggatatac cagtccgtaa atcgaagaac aatcgccatc aggataacag
    22201 ctacccaccc tagcgtatct tccagaaaat gcagactcag aatagactca ttctttgtct
    22261 ttcccttacc aaccaccaga ctcgctaaca gattgatagt aatcgcaata attcctaacc
    22321 agagaatccc ctcatcattg actggctgcg gatgcaaaat cttcgtgaca ttttccaaaa
    22381 cgactagaac agagcccgtt acgagaatca cagctgttac caaggctcct agcaggctaa
    22441 accgcttata gcccaaggtg tactgattgt cttcttcacg attggagatt gtttctagaa
    22501 aagctgatat tccaattgca atcgcatctc ccaagtcatg cacagagtca gcaagaacag
    22561 cgctagaacc aaatactcca cctgcaataa actcaacaat ggcataagtc aaatttaaga
    22621 aaaaagccac ccaaacagca tattttgcct tcatatttct cattcctttg ttataataga
    22681 tttatgaaca ccttgttcat tatcattatc cactaaaact caaagaaagg atagaagcaa
    22741 aacgtcagct ttattcagtt ctgaacaatt tgcctcaagt gtccatatga ctaacattga
    22801 ccgccgtatc agcaaaacca aaaaagccat ctatcaagct tttatacaac ttttgaatgc
    22861 taagggctac gaggccacta ctgttcagga tatcattgat ctcgcagatg tgggacgatc
    22921 caccttttac tgtcactatg agagtaagga gcttcttctg gaccagctct gccgctacct
    22981 cttccatcat ctttttgaaa gagagcaagc catttcaacc gaggactacc tcgcccacct
    23041 ctttctgcat tttcataaaa accaagacca tatcaccagt ctgctatttt ccaaaaatga
    23101 ctacttcctc cgtcaactcc ataaagagct agaacaccat gtctattccg tgctagctga
    23161 taatttaaaa gaagcccacc ctaatctgcc tacttcttac ctccaacact tggtcatgtc
    23221 caactttatc gagacattga cctggtggct caaaaaaggt caagatttca cagaccagga
    23281 agttgtccaa ttttatctag accttctcat tcctaaaaat tgaatataga gtaaagctca
    23341 gttgtcttat ttctagatta ctgagttttt tatcttttca acaacaaaag aggacccgcc
    23401 gatcctcttt ttcatactat aaatccttga ttatcaacta tatctgtttt aatcgaaatc
    23461 tcaaaacagc actttcaaac atcttttcct agttaagtaa atcagtattc tgcttagctg
    23521 ccttgctcca ttgataccaa ccaactagac tgttaatgag ataaattaaa tatttccctt
    23581 gaatttgcag gctttctccc caccagagat agattgaaaa gacattggta gccgcccaga
    23641 atatccactg ttcacggtaa acagctgtca tgaggatttg ccctacccca ttggttgcat
    23701 ctgtgattga atcacgatag ggacgattgg caccaataga ctgataaatg aagccaaagg
    23761 ccaaccacca aagcacacta atggaaagat actttgtcca gcccttgccg tccagtttac
    23821 gcgcgacaaa ctcctgcttt tccttcttaa actgtgcctg ataaatccaa actagaagtc
    23881 caattggctg catgactgtg aagtaaagtg tcgtcagcac ctcaccataa aagcctttct
    23941 gtagggccaa aataaggtaa ataacagagt taatcaagcc aaaaagataa ttacttgctc
    24001 gaccttccga tacaaagatt acacagataa tccctgtcaa gctacaaatc atcccaatcc
    24061 aatcaacaat acgatgttcg taaaccaact ccagccagag aggaaaactt cctaaaacca
    24121 gcaaataaat ccactgagca aaactacgat gggcaaagag gtcatcccag atagccttca
    24181 tagttcctga aaatcctaaa tcagccatag ccgcaaccat acgacggtaa ccacctgaca
    24241 tttcacctag ggttgttttg atattttcaa ttttcttttg caaataagta tgcatcattt
    24301 ctccttttgt ttttaaagag ccgtgtctgg atagactttc ggacgcaacg ctctattaga
    24361 taatgaactg cctatacaca agatttctaa ccttagtcga catgagctga aacctcttat
    24421 ttgttaagta gttcacaaaa tattatacac ctattttatg aatagtcaac tgtctttaca
    24481 gtaaaatttt agaaaatcat gaaaattttc tctttctttc cattttaagt gacattcagt
    24541 cattctcaca tcaaaaaagc ccagacgaaa ttgtctgagc attcttttat ctagtcgttt
    24601 aaggaagttg agttcagtat gtttaaagtc tctgtcccat catttcttca acaaaccttg
    24661 ttcttgtaga aattccttgg ctacttgttc tgctggcttg ccttcgacac cgacttgata
    24721 gttaagctgg ctcatctggc tttctgtaat cttaccagcc aatttattaa gaacagtttc
    24781 caactctggg tgtttcttga gaagagcttc tttcatgagt ggagcccctt gataaggtgg
    24841 gaagagttgc ttgtcatctt ccaagacctg taaatcataa cgctccaatt ccgcatcagt
    24901 cgaataggca tccgtgattt gaatatcccc tgactgaatt gcctgataac gaagagctgg
    24961 ctgcatagtc gccacattga gattgagacc atacattgat tgcaagccct tatttccatc
    25021 ttcacggtcg ttaaactcaa gcgtaaagcc tgccttcagc tgcccttcca cttttttcaa
    25081 atccgaaatg gtcttcaagc catattcttg agcaatcttt ttcggaacag ctacagcata
    25141 ggtattttga taagacatag gtttgagata ggctagatga tcctgcttgg caatgccatc
    25201 acgcgccact tgataaacct gctctggctc atgactcacc ttgggtgatg gttgaagcaa
    25261 actttcagtc accgtaccgg taaattcagg ataaatgtca atatcacctt ttttcagagc
    25321 ttcataaagg aaacttgtcg tcccaaaatt cggtttaaca gtcgcagtca tgctggtatt
    25381 ttcttcaatc agcaacttat acatattagc caaaatttct ggttctgggc ctattttccc
    25441 agcaataatc aagttttcct tctctttttg agccaaaaga gctggactat aagacagacc
    25501 cagtaataaa gccaccaagg caaaacctga gaaaatcgtc cgtaattttg ctttttccat
    25561 tacttttagt aggaagttaa aggcgatagc aagcactgca gaagaaagtg ccccaatcaa
    25621 aatcaaactg gcattattac ggtcaattcc caacaggata aaggaaccca gtccccctgc
    25681 tccaatcaag gccgccaagg ttgccgtacc gataatcaaa acagctgccg tccgaatccc
    25741 agacatgata acaggcatgg cgagtggaat ttcaaatttc ttgagacgtt cccatctggt
    25801 catcccaaag gcaatcccag cctcttgcag gttcggatca attcccttca gcccagtgat
    25861 agtattttgc aaaataggga aaatcgcata aatcactaga gctgtcaaag ccggcaaggt
    25921 cccaattccc atcaaaggga taaagagccc caacaaggcc agagacggga tggtctggaa
    25981 aatacctgca atctgcaaga cccagtcggc cagcttctca tgatagcgaa gaaaaacagc
    26041 caagggaatc gcaagcaaaa tagctagtaa caaggtcaaa agtgacaact gcaaatgttg
    26101 agatagagct gtcaaccaat cactaaaacg atcctgaaaa gttgcaatta aattagtcat
    26161 gaacactacc tccaaacaag tctgctacaa agtctgttgc aggcgctttt aaaattgtct
    26221 cgggattcgc tacctggcga atttctccat cctgcaagac agcaatacgg tccgccaact
    26281 tcaaggcttc atccgtatca tgggttacaa aaatcgttgt catcccaaac tctttatgca
    26341 attcttttgt cagaacctgc aactgttttc tcgaaatagc atccaaggcc gaaaagggtt
    26401 catccatgag gaaaatcttg ggctgaccaa tcatagctcg gacaataccg acccgttgct
    26461 gttctccacc agataattca ctaggtaagc gatgcccata ctcggctact ggtaaaccaa
    26521 ccttagccaa aagctcttct gttttcttcg taatttcttc cttgctccac cccttcattt
    26581 caggaatgag agcaatattt tccgcaactg ttagatttgg aaaaagagca atagcctgta
    26641 aaacataacc agtagaaaga cgaagttcac gctcatcata gtctttgatg cgcttcccat
    26701 ccatataaat atttccatca gttggttcca aaagacggtt aatcatcttg agcatggtcg
    26761 tcttacctga cccagaaggc cctactaaaa ccataaattc cccatcctca atctgtaagt
    26821 tgacatctct caagacatcc ttttctgtgt agcgcagtgc tacatttttg tattcaatca
    26881 ttctttgtcc tcaatttaaa acttccctcg attagtcaag tcttctacct taggcatgac
    26941 ttccttatta tcccaatgct ccacaatttt cccgttctct aaacggaaga tatcgtactg
    27001 ggcataagca acgccatcaa tctgagtctg accatagcta accacatagt ttccttgtcc
    27061 taagagttgg aaaacaaagt caaaagtgac actatattca gccacatagt ttttataagc
    27121 agcacttcct tgtccaatct catgattatg ctgaatcaaa tcgtctgcca cataatcact
    27181 ccactgctct agctccccat tttggaaaat ttctgtcaag aaacggcgaa ccagcttttt
    27241 attttctgct ttcttatcca aatccttgat ttcaaaatct ccaaaaattt gatctagttg
    27301 atcattttca ggtgttcgat agtagtcaat gacatcccaa tgctcaacaa tacgaccatt
    27361 ctcatccgca cggaaagtat ccgtcgtcac ccattgagct tctccaccat tcagatattg
    27421 atgaacatga acaaagacca gattgccatc ctcaatggtg cggacaatct taatctgacg
    27481 ctctggatga cgctcaaaga aatctgcaaa gaaggctgca aatccttctt tcccgtcagg
    27541 aacacctgtc gaatgttgga tataggtatc ccctacagac tgggcttgag cctcagcaac
    27601 tcgtccgtct tgaatggcat ggatgtatag gttgtgagca tttttcactt gttgtgacat
    27661 attctaaacc tcatttccct tctctttcaa attcgccaaa attctttctt gaaaaccttc
    27721 aaattggtga atttcttcct ctgaaaatcc tttgtaaaag atagtatcca atttctgact
    27781 gacacgatgc cccacttctt tctgggactt gcctaactcc gttaaaacta aatacttctt
    27841 acgcttgtct tttccacacg gactaacaat tacaagcttt tgttcctcta gcttttttat
    27901 catagtcgtc agcgtattat tcgcaagccc agtcgcaagc gcgatatctg tcgcagttgc
    27961 gcagccagtt tcactattcc ataaaaccgc taaaatcttg ccctgttcac ccctataaag
    28021 agcctcagga tcttgactca gtaacttttg aaaaatccgc ccattcaaca aacgaatatg
    28081 atgggctagc aaatgactat ctttcataac acctccaatt tatttcgatg tcgaaatgaa
    28141 taaaataatt gtaacactca tcgttctaac tgtcaactat ttcgatttgg aaataatttt
    28201 tgataattat tcacaccacc atactccggc tcaactaact tttaacgaga gtttctaaat
    28261 tccttcgtcc tccagtctac aaaagccttc catccgtact atcctatttt ttatgagggg
    28321 acacattttt cctatcagat catttatttt aaagatagaa gtaaatcata attgcttcca
    28381 tctgttcttt tatagtatat tgaagttgga ctagggcact gtatcttcta aaacattgat
    28441 agaaagcgat ttgaatttcc caatcaattt gttcgtcttt atagcatttc gaaactggaa
    28501 taggacacca tgactgctaa aagatttcta taaattcatt tgatttccct aatcaatttg
    28561 ttcatatctt atttcattcc gctataattt caccttaccc tatctttttc gtagcaccct
    28621 tcaaacagcc tatcccctac cgtttgacga ttcctcactt cactccactt ccattacaga
    28681 agtttcttca ctactatggt ctcggctgac ttctcatgat tccttgttac tactatttga
    28741 acgctcacga gataggtctt ataaaaaatg ctttgatcca caatggaatc aaagcatttt
    28801 aaaaagttcc tcatacataa gtgcagaagt cgcagttcct ctgtacttgg cttcttctct
    28861 tttgataaag cgagccaagt tgagcaactc aggtgctgga tgtttgggat ttaggagcaa
    28921 ttcacgattg accaggcctg agagacgaac tgcctgcaat tgctcatttg tagtaggcag
    28981 ttttttagta gtctctagga gagcagcaac taaatcttca ctcaaatcat gtcgagcatg
    29041 attgtaaaga tcttttataa ggctttctag gtttggttct gccatcccta ccacctccct
    29101 tatggtttaa taatgtttaa tcaaatcaac cgttgaacga tccaatttct tcaccaaggc
    29161 ttgtaagaaa gcttgcgctt ctaggaagtc atccattgca tagagggttt ggtgagaatg
    29221 gatataacga gcgcagacac cgatagttgt tgatgggaca ccaccatttt tcagatgagc
    29281 tgcacctgca tctgttccgc ctttaccaca gtagtattgg tacttgatac cagcttcttc
    29341 agccgttgtc aaaaggaaat ccttcatccc tgggagaagc aagtgacctg gatcatagaa
    29401 acgaatcaag gttccatctc caatcttgcc ttgaccaccg tagacatcac ctgctgggga
    29461 gcaatcaact gctaggaaga cttctgggtc aaacttggtt gtagaggtat gagcgccacg
    29521 cagaccaact tcttcttgga cgttagaacc cagatagagt tcattgccga atttttgacc
    29581 tgataaagct tcagctagct cgcttaccat gaggacaccg tagcggttat cccaagcttt
    29641 tgagatgata tttttttcat tggctgtcaa aattgcagaa ctatctggta cgatggtatc
    29701 accaggacgg atgccaaaac tttctgcctc agccttgtcc gcaaaaccac catcaaaaac
    29761 gatatcggca atggctggca tggttggtcc cccctttcca cgagtcaaat gcggaggaac
    29821 agaacctgaa atcacaggaa tttcatgacc atcacgagtc aagagtttga aacgttggct
    29881 gctaaccacc atggggttcc agccaccgat ttctacgaca cggaaggtac catctggctt
    29941 gatttcgctg accataaaac caacttcgtc catatgagaa gcgaccaaga cgcgcggtgc
    30001 atccacagct tctgaatgtt tgataccaaa aataccaccc aagccatctg tcaccacttc
    30061 atccacatgc ggtgtcaact tttcacgaag ataagcacgg acaggcgctt catgacctga
    30121 gactgcagca agttctgtta cttctttaat ttttgaaaat aatgttgtca tttcagttcc
    30181 ttctttcttt catccatttt accacttttt ataggagaag gatagtggga aggtggattt
    30241 ctaagttagt atcttagtcc tgctctatct tagaaaagga tagtattctc ttgcatgtag
    30301 tgcaaaatct agtaaacatt ccaaaattaa ctcgaatatt tatttccaaa caaaaaacaa
    30361 tacaccatca aagttgtttg gatttttcat gaaatttaca gaaaatagtt gacttccctt
    30421 tcttctttct ttaaatatat agttggttga gtttggaata gtacgctgta gctgctaaaa
    30481 catttctaga aattaatttg actttcctaa tagagttgtt catatcttat ttcaatttac
    30541 tatagtacaa aactagaaaa ggaaaaaatc atgaccaaaa caattcttgt tacaggtggg
    30601 actagctaca ttggctccca taccgttaaa gctcttttaa atgctggcta taaggtgcat
    30661 gtcctcgata atctctccac aggaaatcga gcggctgtgg atagtcgtgc tagctttaaa
    30721 gaactggatg tttatgatgc tagcgcctta aaggcttact taaaagaaaa tcagattgat
    30781 gctgtcctcc attatgcagg tgaaattgtt gtgagtgaaa ttgttgtgag cgaaagtatt
    30841 gaaaatccaa gtaaatactt cactgccaac gttgctggta ggaaccaagt tctcaaagtc
    30901 ttatctgaag ttggcactca aaaaatcatg ttctcttcga ctgcttctct ctatggaaat
    30961 aactgtattg acaagccggc gactgaagat accctgatcg accctgtcaa cccttataca
    31021 gagacaaaac tgatgggcga acgaatgatt tactggatgg ccaatcgcta cgactggaaa
    31081 tatgttattt tccgttactt taatgttgct ggggctgaaa tggatgcttc aaacggtctg
    31141 cgtgtgaaaa atccaactca catcattcca aatatcaaca agaccgcatt gggacaaaat
    31201 gatagcttaa aaatatttgg agatgactac gatacacgtg acggttcatg tattcgagat
    31261 tacatttatg tcttggacct tgcataggct catgttaaag gaatgaacta cctatttcaa
    31321 gaagacagtt cttctcaaat ctttaactta ggaactaaaa aaggctatac tatcaaagaa
    31381 atctttaaaa ctgctgaaga attactaaat taaaaaatcc cacacgagat tgttgctcga
    31441 cgtgctagtg acccagccag tgtcctagca gatgcttcaa aagctaaaca atatcttgat
    31501 tggacggcta gctactccct cgaagatatt attttatcag attaaggtaa aaacatttta
    31561 gaataggata acaaaggaga aagtcttgtt gctctctcct tgttgtattt attaaattgt
    31621 cagaaatttt attgacagat tagaaaaata atgttacatt tatatccgca gatatctttc
    31681 gataccaaat ctacatgaaa ggacggggta tgaaactttc tcattattta attggcttac
    31741 ttctactcct agtctttctc tctattagca ttgggaccag tgatttttca tggggaaagc
    31801 tatttgattt cgaccagcag acctggctcc tctttcaaga gtcccgtctc ccaagaacta
    31861 tcagtattct cctgactgcc tctagtatga gtatggcagg ccttctcatg cagactatta
    31921 cccaaaatca gtttgctgca ccgagtacag ttggaacgac tgaagccgcc aaactgggaa
    31981 tggtgctgag cctttttgta tttccatcgg ctagtctgac ccaaaagatg ctcttcgctt
    32041 ttgtttcatc catcgtattc accctcttct tcctagcctt tatgaccatt tttactgtaa
    32101 agaaaaggtg gatgttgcct ctgattggga tcatctatag cgggattatc ggctcagtca
    32161 cagaagttat cgcctatcgt ttcaatctgg ttcagagtat gactgcctgg acccagggct
    32221 ccttctccat gattcagacc catcagtatg agtggctctt cttaggcctc atcatcctga
    32281 taaccgtttg gaaattatcc caaaccttca ccatcatgaa tctagggaaa gaaaccagcg
    32341 agagtttggg gatttcctac tccctacttg aaaaactggc cctctttctg gtggcgctaa
    32401 cgacaagcgt caccatgatt accgtgggtg gcctaccatt tctcggagtt atcgttccca
    32461 atcttgttcg caagtgctat ggagataatc taagtcaaac caaactcatg gtcgcactgg
    32521 ttggtgccaa tctagttctg gcttgcgata tcctatcccg agttctgatt aggccctatg
    32581 agttgtctgt cagtctcttg ctaggaatca tcggtagtct cgtctttatc ctacttctct
    32641 ggagaggggg acgaaaagat gcagactaaa agcaaacata ccaagctctt ctggattctc
    32701 attattcttg ccatcggagc ttgtcttctc tacttttggc ccatcactca cttgtcagcc
    32761 tttgcttgga agttgcgttc ccaaaagatc atcgtttatc tcttggtagc catcgcgact
    32821 gggatttcga ccattagttt tcaaaccctg acggaaaatc gcttcctgac gcctagtatt
    32881 ttgggaattg aatccttcta catcctacta caaaccctac tactggtttt tgaaagcaag
    32941 tttcttcaac ttggcaaatc ccctatctta gaattcctag tcttacttct tgtccagtcc
    33001 ctcttctttc tcgccttaca aggttacttg aagacactga tgaagcaaga cctggtcttc
    33061 atcctgctga tctgtctagc gctcagaagt ctctttcgaa atatcagcac cttccttcaa
    33121 gtcctaatgg atccaaacga atacgataaa ctgcaaaata gtctttttgc ctcctttcaa
    33181 catctcaaca cttccatcct agccatcggt tctctgatca tcctcgcttt gacaatcttt
    33241 ttctttcgaa aagcagtcgt tctagatgtc ttgcacctgc aaagagaaac ggctcagata
    33301 ttgggactcg atgttgaaaa agaacagaaa gagctcctct ggggaatcgt gcttttgacc
    33361 tcaacggcca ctgccttggt aggacctatg gccttcttcg gctttatgct ggccaacctc
    33421 acctacctga ttgtcaaaga ctatcagcac aagttactct ttatagtggc cattctggtt
    33481 ggatttatta gcttaacctt ggggcaagcc ttgattgaac gagtctttgc actggaaatt
    33541 cgtatcagta tgatcattga gagtgtgggt ggcttcttat tctttatctt actatatagg
    33601 agggctcgtc agtgaaactg gaaaacattg acaaatccat tcaaaaacag gatattttgc
    33661 aaggcatttc gcttgaagtc agtcctcaaa aactgacagc ctttattggt ccaaatggtg
    33721 ctggaaaatc gactctcctc tccatcatga gcagactaac caagaaagat cagggagttc
    33781 tcagtatcaa aggacgtgaa atcgagagct ggaattcgca agaactggcc caagaactaa
    33841 ccatcctaaa acagaaaatc aattaccaag ccaaattgac tgttgaagaa ctggtcagtt
    33901 ttggacgttt tccctacagc cgaggtcgac ttagatcaga agactgggaa aaaatccgag
    33961 aaactctgaa ctatttggaa ctgaccaact taaaagaccg ctacatcaat agcctgtcag
    34021 gggggcaact ccagcgcgtc tttatcgcta tggtactggc ccaggatacg gactttatct
    34081 tgctggacga accactcaac aatctcgata tcaagcaaag cgtcagcatg atgcaaattc
    34141 ttcgacgact ggtggaggaa ctcggcaaga ccattatcat cgtcctccac gatatcaaca
    34201 tggccagtca gtatgcagat gaaattgtcg ccttcaagga cggtcaggtc tttagcaagg
    34261 gaagcaccga tcaaatcatg caggctgacc tgctcagcca actttatgag attcccatca
    34321 cgctagctga tatcaatgac aaaaagatct gtatctatag ctagtaacat aaaagctcaa
    34381 gttagagaac cttcagtctc ttaatcaata agatcaagag actccctaaa tcgttatcac
    34441 attttaaaaa ggagaaatta tgaaaacatc ccttaaactt tatttcactg ccctagtggc
    34501 cagcttcttg ctcctacttg gtgcatgtag tacaaactca agcactagtc agacagagac
    34561 cagtagctct gctccaacag aggtaaccat taaaagttca ctggacgagg tcaaactttc
    34621 caaagttcct gaaaagattg tgacctttga cctcggcgct gcggatacta ttcgcgcttt
    34681 aggatttgaa aaaaatatcg tcggaatgcc tacaaaaact gttccgactt atctaaaaga
    34741 cctagtggga actgtcaaaa atgttggttc tatgaaagaa cctgatttag aagctatcgc
    34801 cgcccttgag cctgatttga ttatcgcttc accacgtaca caaaaattcg tagacaaatt
    34861 caaagaaatc gccccaaccg ttctcttcca agcaagcaag gacgactact ggacttctac
    34921 caaggctaat atcgaatcct tagcaagtgc cttcggcgaa actggtacac agaaagccaa
    34981 ggaagaattg gccaagctag acaagagcat ccaagaagtc gctactaaaa atgaaagctc
    35041 tgacaaaaag gcccttgcga tcctccttaa tgaaggaaaa atggcagcct ttggtgccaa
    35101 atctcgtttc tctttcttgt accaaacctt gaaattcaaa ccaactgata caacatttga
    35161 agactcacgc cacggacaag aagtcagctt tgaaagtgtc aaagaaatca accctgacat
    35221 cctctttgtc atcaaccgta cccttgccat cggtggggac aactctagca acgacggtgt
    35281 cctagaaaat gcccttatcg ctgaaacacc tgctgctaaa aatggtaaga ttatccaact
    35341 aacaccagac ctctggtatc taagcggagg cggacttgaa tcaacaaaac tcatgattga
    35401 agacatacaa aaagctttga aataagccac ttcaaactca atttaatact caatgaaaat
    35461 caaagagcaa actaggaaac tagccgcagg ttgctcaaaa cactgttttg aggttgcaga
    35521 tgaaagctga cgcggtttga agggattttc gaagagtata aaattttgac attctaaaac
    35581 gcatcctatc aagttcactc aaacctgata ggatgcgttt ttatcatttt gaaatctatt
    35641 taccccacct cattcccctt cttgatttcg tttaagggaa aagtggtctg gaacggggtc
    35701 cttacctgtt ttcgaccagg gatgacaacg taaaatccga gccaagccca tcaatacccc
    35761 cttaaaacca tgtttttcaa tagcctgaat catgtagttg gaacaagtca gctcaaagcg
    35821 acaagagggt ggaaagactg gtgagataaa acgttggtaa aagcgcacag gcgctattaa
    35881 aattcgtttc attatttctt agttacagcc atggtgtgta gttggctgat ttctttttta
    35941 ttaagacgac gggattctcc tggacggagt cctgtcaagt ctaggtgtcc gaaacgagtc
    36001 cgagacaact tatctacttg gagaccaaca gcttcaaaca tctttttaac ctgatggtta
    36061 cgcccttcat ggatggtcaa ctgcaccaca gagcgatttt tgactgggtc cactttgaga
    36121 atttcataaa cagctggctt ggttttctta ccatcaatct caagaccacg ggtcaagggg
    36181 cggagattgt ccttattggc cacaccttta acacgcgcga cataaacctt gtcaatctca
    36241 ttacgagggt gaatcatctc gtctgtaaag tccccatcat tggtcaaaat caagacacct
    36301 gatgtatccc agtccaaacg acccacaggg taaatacgtt ctttgacatt gggcaagagg
    36361 tcgacaaccg tcttgcgacc cttatcatct gtcacactgg aaatcacacc gcgtggtttg
    36421 ttaagcagat agtaaacctt ttcttcgttg tagataggtt gaccttcaac ttcgaccttg
    36481 tcgcctgact tgatagtggt tgctagttca cgcaccactt ggccgttaac cgtcaccaag
    36541 ccttgcttaa tcagctcttc tgcttttctc ctactggcca cacctgcgtg ggcaatatac
    36601 ttattgattc tcatcttctt ctatcctttc accaaataat tggctttctt gggcttgaat
    36661 ctcaagctca tcaatcactg gtaattcttc taaatggttt atccccatgt aatctaggaa
    36721 ataatccgta gtcacataga ggttggggcg ccccaatact tcctttttcc cgtcttcctt
    36781 tatcaggtca aaagcctgca actttgccaa ggctccactc gagttaaccc cacggatggc
    36841 atcaatttct atccgcgtaa tcggctgttt gtaggcaata atggacaagg tctcaagggc
    36901 agcccgagac aagctctggt tgataggcgc cttagagtat tccttcaaaa tctctgcaaa
    36961 ttgaggcttg gtcaccaatc tataagcacc acttgtctca atcaaagcca aactggaatc
    37021 tgggtccttt tcatacttct gggctaattt tcctaaactt tgctggatgc ctgtcggtgg
    37081 cagagagagg agttcagcta actggcggac ccgaatccca tcttcacccg ctacaaacaa
    37141 gagcgcttct atttttgcta aagtactcat ctttcctctc tatcaagtct agctttgagg
    37201 cacttgactt tcttccttct tttccatgag atagatatct ccaaaactct cctcttgcac
    37261 gaggatcagc tcctgggttt tgattaactc tagggttgcc aaaaagaggg tgatgacctc
    37321 ttggacattc tgggcttcct tgaacaaatc ctgcaagcgc aattgatctc gtccaatcaa
    37381 ggattctttc acaataatca tcatgtcctc aatcttatac tcatcccgca agatagtcgt
    37441 gtgattttgt gcaaactcct cttttttctt ggctaggata tttgaaaaag ccaaaaagag
    37501 gtcaatggtc gtcttgtcat gcacaagctc cgcatcttcg taaatcaact ctgtcggcgc
    37561 tttggaataa tactgggccc gttcttggtg cttggcttcc aagtgctcac ccaagagctt
    37621 gaacttgcga tattcttcga tttgagagag gaggtcctgc tccaggtcat cccccaagtc
    37681 tgtcacttct gctaccttcg gaaggagttt acgactctta atcagcatga gctgactagc
    37741 catgaccatg tactcacccg tcacttccag acgcatggcc tgcagggttg agacataggc
    37801 tagatactgt tcgatgactt ccgtaatggg cacatcgtag atatccatct ggtacttaga
    37861 aaccagatgc aagagtaagt ccaggggtcc ttcaaaatct tttaatttaa tatccattat
    37921 ctatattttt ctaaggtcag gactgttttt aatcctaatt tttttgcaat ttcgtacaaa
    37981 tcgaccttgt tttctatttg tcttagaata aactgttcac gtaagacttg agctgataag
    38041 gatggaaaac ctttctcctt gacaaaagat tctaactgac gaaaggccca ctgacgagaa
    38101 tagggtttcc ctcctctttc aaaaagatag gtctgcccca tcaagggttc caattctgaa
    38161 agcaaggccg tgggaatggt gacaatcctc cgttgggaag ccttgctgat tcgcaacacc
    38221 tgaaaatcca gattgatgtc cgcaaccttg atggctaaaa tctcactggg caagagcccc
    38281 atttctagga ttaagagcgc tagcaagcgg ccctctggat ggtcgctttc ctgccaaaaa
    38341 gagtctaggt atagaatctc tggcttttcc gtcttctttt cagcttgttt ggctaattcc
    38401 aagcggtaaa agctgtccac ctctcctttt tgatagagaa agtatagaaa ttggttacag
    38461 gccgaaatct ttcgcttctg ggcgctgatt tttagattgg ctagctgggc ttggtaaatc
    38521 ttgagactgg tctcagaaat ccgctcacct accatgtcta aaaattgctc caaatcatac
    38581 ttataggact gcttggaatt gacagacaag ccctgctttt cctctaaaaa ggctgaaatc
    38641 ctgtctctca ttggcatcga atctcatatt ccttactaaa gtcatgcaag agggcattaa
    38701 cggccttgag gatggacttg cgcgtaataa tcccttggaa aataccctct gcatccacaa
    38761 ccggtaagaa ggactcatct actagcttgt gcaagacctc cgtaatggtg aaatcaggcg
    38821 aaacaaccgc tacgtccgtt tttgtcatat gaacgatatc cgtatccgcc atgatttctt
    38881 ggctcaagtc atgctccatc tgataagcca taatatctct gagtccaatc gtcccaacaa
    38941 actgtttttc atctgtcaca acgggaacac gggtataggt catctgactg agcaagaggg
    39001 tcgcatgatc cgcattgtga gtatcaatca acacagctag atttttagca ggggtcaaaa
    39061 aagtttcctc ctgccccaac aagaaagtct caaactcctt ggcaatcatc ggctaaactc
    39121 cttggacaaa cctggataca cctcgtgatc tcgtgtcaaa aagtccactt tgaagtaact
    39181 atcatcaatc tccacacgag catagagaca ttctctgatg gtacctcgtg gttgactgat
    39241 agagcctgga tttagaaaga ggatcttgcc ttccaaccaa gcacttggca catgcaagtg
    39301 accatagagg cagatagcgg cctcttcctc ctgagcccag tagtccaact tttgaaagtt
    39361 gaaattgatg tcaaacaagt gaccatgagt ttggataatc ttggtcgaac caagctcagt
    39421 caccagacgt tctgggtagc cggcgtagaa gtccatgttc cctttaacaa cgcggatgcc
    39481 ctcccaaagt ggagaatccg gacgtagttc agaatcgccg ttatgaaaaa cggcatcgac
    39541 tttgcccaca tagcgatcac ggacttcttc cacaatcaag ctatcgccat gggaatcgct
    39601 cattacaatg atggtttgct ttgccatgat ggaaatacct ccaaaagttt cttaacggct
    39661 aaggcacggt gagattgact atttttttct tccagggtta attcagctga tgactcacct
    39721 gtctctccta caaggaagag gggatcatag ccaaagccat tttcaccctt aggttcaaag
    39781 ttaatataac ctgaccagtc tgcttcaaca actaaacttt ccttatttgg gctggctacg
    39841 actagggttg tgtggaactg agccgagcgg tccttgagtt caaagaccat ggccaattcg
    39901 tgcaagagtt tggcattatt ttcacggtca gttgctccca cacctgcgaa acgagctgac
    39961 cagacgcctg gtaagccacc aaggacatcg actttgagac cagaatcatc tgccaaaacc
    40021 atcttgcccg ttaattgaga aatggtttct gccttaaggc gggcattttc ctcaaaggtc
    40081 atacctgttt ctgctacttc aggcaggtca gggtagtcat taagattttc cacatcgtag
    40141 cctaacttat caaagatagc tcggaattcc ttggttttac cttcgttacg agtcgcaatc
    40201 aacaaggttt ctctgacttt gcttgtctca aagaaatcat gaacattgac cccttcttta
    40261 ggcaattcta catacaagag ttgcccattt tcaaccaaga gcagggcccc atgacgttga
    40321 ataacttcca agtttcgtcc catttcttga ttaagcatat ctaccacaaa ggagaacaaa
    40381 cggtaggtag aaccatagcg taaaacagta actgaaagcg ggaaaccata ctcttcatct
    40441 ccaaatattt tggagaattc aaacagagga aaatctgtct gatagtcgct caaactgtta
    40501 acgccaccaa aaatactata agacccaaca taccagtcct ggtcatcctt atattcataa
    40561 attttatttg tcataattct acatgctcca catgaatctc tttttccagc cattcttcac
    40621 caatttgtgc aaaactttgg ctactggctg ttgtgtaaaa acggtgatgg agtggtccag
    40681 catcgcgacc acgattgatt tcaaaataat tgagtaagac tgagatatcc cgtacgcact
    40741 ctgccccact atcgatgagc tgaacctttg gccccatcac attttggata atagggcgaa
    40801 ggagtggata atgagtacag cccaaaatca ggctatccac ctttccaacc aagggacgca
    40861 gggtttcata gaccaccttc ttggtaacac tggttgacag ggcacctgac tcaaccaagg
    40921 gagcaaactt gggacaggcc aagctctcca cctgtaagtc gggatccaga tcatggattt
    40981 tctgacggta tatgtctgat tgtaccgtca tgggcgttcc aatcactccg attttcccac
    41041 cttgactgga cttgatggct gccgaagctc ctggcaaaat tacacccaag acaggaatat
    41101 ctagttgagc cttgatttct tcccagacga ccgcagtcgc agtgttacaa gcaatgacaa
    41161 tcattttgac atccttggtc aagagaaagt tgaccagctg ccaagtatat tcacgaattt
    41221 gctcagcagg acgggggcca tagggcgccc gcgccgaatc tccaatatag acgatttctt
    41281 catggggaag ctggcgcatg agctcgcgca caacggtcaa gcccccgaca cccgaatcca
    41341 aaaaaccaat tggtcgatta tccatacagt cttctttcta gtcttttttc tgattgatcg
    41401 ttcattatga ttccttgtac tgaacgaact gaccgacagc ttgatagaat gtcaactacc
    41461 tctctcttaa tcataatcaa atatcaatag aatgcaagga aaaagtctca tccctaaacc
    41521 ataaccaaca tagtgagaag tctggaactt tcatcccaga cttttcctta tttatttttt
    41581 ctttttattg ttagcaaggg ctgccttttg ttggcggatg atttggtggt aaacttgttg
    41641 taccttagct tcgcttggtt tttgaccatt tgcactcaaa agagtacgaa ctgcttcagc
    41701 attcaaacgt gggttgtcag caaattcttt ttcgatttgc ttacgaacca agtacattcc
    41761 tccaagagct cctcctagaa aagctagcac aatcaataca attgctaaaa gtaaatccat
    41821 catttttctc ctgtttcttt ttgaatccct ttcattatac cacaaactag ccaccctgac
    41881 cagtttgttc tacactttca gggatggaat agacagcaaa aagaaccctg cttttctgaa
    41941 aaagaggtct ccttgctaag tttatactca atgaaaatca aagagcaaac taggaagcta
    42001 gccacaggtt gctcaaagca ccgctttgag gttgcagata aaactgacac ggtttgaaga
    42061 gattttcgaa gagtattaat ttacataaat agccagtgtt tgatagggtt tgagtagaat
    42121 tttctcagac acttctgcat cttcatagtt tgatatcaaa atctgtccat tttggtagac
    42181 tgctggcaag tcgatttcca cttctttagc ataaaagtta ttgagcacta gtaacttttg
    42241 atcctcaaac tggcgttcaa aagcgtagac ttgtttgcta tcttcaaagg ctggtttgta
    42301 acttccttct gaaatgattg gcatttcctt acgcagtcga atcaagtctt gatagaaggt
    42361 gaaaatcgga ccctggattt cattttctac attgatgtat ttataggatt taccagcttt
    42421 caaccatgga gtgcctgttg aaaatcctgc attttccgaa gcatcccact gcatgggaat
    42481 gcgtgaatta tcacgcgact tagcttgaat aatctggaag gcttcttgct gactctttcc
    42541 ttcttctaag agcgtctgat aggcattaag cgattcgaca tccacataat cagccataga
    42601 atcatagtct gggtcaatca tcccgatttc ttcacccata tagatataag gtgtcccacg
    42661 tgacaggtga atgctagccg ctagcatggt ggctccttcc ttgcggaagt tttgaatatc
    42721 gacaaaacgg ttcaaggcac gtggttgatc gtgattgttc caaaagaggg cactccaacc
    42781 gtctttatca ctcatttcct taccccaact atggtaaaga ctcttcaact cttcaaaatc
    42841 aaagggagcc aaggtccact tttgtccatc cttatagtcc accttgaggt gatgaaaatt
    42901 aaaggtcatg gataattcct gacgatcagg cgacgaatag aggacacagt tttccatggt
    42961 ggtagaagac atttccccaa ctgtcataaa gctatcgtca gatccaaaag tggcttggtt
    43021 catcatacgc aaatagttat gaacgatggg tttgtctgta taagctggct tcccttcatt
    43081 ttcaggacag tccactgaaa cctcgtcctt accgatcaaa ttgatcacat caaatcggaa
    43141 acctttgata cccttgtcgc gccagaaatt aacaaccttg aaaagctcct tacggacatt
    43201 ggaattgcgc cagttaaggt cagcctgggt ctcatcaaat aggtgaagat agtatttccc
    43261 agtatccccg aaaggcgtcc atgcagaacc accaaactta gactgccaat ctgttggttg
    43321 gtcttggatg aagaaaaagt cttgataata cttatcacca gctagggctt tctgaaacca
    43381 ttcatgctct gtcgaacaat gattaagtac catgtccagc ataaagtcaa tcttgtgctc
    43441 tttaccgaca cacaccattt cctcaaaatc agccatatca ccaaaaagag gatccactgc
    43501 catataatct gaaatatcgt aaccattatc ccgttgaggg cttggataga atggattgag
    43561 ccagaccata tccacaccta gtttggctaa atagggaatt ttttcgataa tcccacggaa
    43621 atccccaata ccgttttcag tggtgtcttt gtaagatttt ggatagattt gatagactac
    43681 ttttccttta tcaagtgtca tctgtttctc cttttctgat aaaagggagg aagcagtctt
    43741 ccgtccctat ttgtgctatt tcaattatac tcaatgaaaa tcaaagaaca aactaggaag
    43801 ctagccacag gttgctcaaa acactatttt gaggttgcag atagagctga cgtggtttga
    43861 agagattttc gaagagtatt agattcgtgt agcgaccatg agagatgctc cagcttggat
    43921 cgttgtcgga taagttccgg gaatagtcgc tgtataagca tcttggttgg tgatgataac
    43981 aggagtttct gtcaccagac ctgcagcctt aatgacatcc atatcaaaac gaatcagttg
    44041 ctgaccaact gtaacgtgat ctccttggac tacaagactt tcaaaacctt tgccatcaag
    44101 acctactgta tccataccga tgtggatgag caattcaact ccctcgtcag agacaatgcc
    44161 gatggcatgc ttggtaggga aaagaaccgt cactgtccca ttaactggag aggtcaactc
    44221 accttggctt ggttcaatga ctagaccttg ccccatgaca cctgatgcaa aaataggatc
    44281 cgtcgcttga ctcaattctt tcacttggcc agttagtggg ctgataattt ctaccgaagt
    44341 aagttctact ggttcatggt tcacaaattc tgcttcttct tgagcaacga attctgcctg
    44401 caagttcgta tcgccctctg tttttgtaaa gagaccagcc ttgcggaaga agaaagtcaa
    44461 gagcattgga acaacaatcg caactagcat agttcctgca aatggcagca tgtattgagg
    44521 ttgaatagag agaatacctg gcaaaccacc gataccaata gaagccgcag ttacattaaa
    44581 agtaacggat aacatgcctg caagggctga accagtcatc ccagcaacaa atggataaat
    44641 atattttacg ttaaccccaa aaagagctgg ttctgtaaca ccgagatagg ctgaaatggt
    44701 tgcaggaagt gaaacctgag cctcacgctc atcatggcga tgcatgaaat aatagacaaa
    44761 cacggctgag ccttgagcaa tattagaaag agcaatcatt ggccataggg cagtgccacc
    44821 agcatccgca atcaattgtg tatcaatggc attggtcata tggtgcagac ctgtgatgac
    44881 aaatggagcg tagagggcac caaaaattgc accgaagagc catttaactg gaccagttaa
    44941 acctgccaag acaactgatg aaagtccttg tccaattgtc caaccgattg gtcccaaaac
    45001 agtatgagcc aaaatcaagg ctggaatcaa tgacaagaaa ggtacaaaaa tcatagaaat
    45061 gacttctggg atatgcttgc gccagaagat ttcaagataa gacagactca aacctgcaag
    45121 caaggctggg ataacttggg cttggtaacc gatacgatta acagtaaaat agccaaaatt
    45181 ccaaacccag tttgccgcga tatcagctgc tggcgttgaa gcaaccgcat aggcattgag
    45241 caactgaggc gataccaaac agattccgag aacaattccc aaaatttggc tggttcccat
    45301 cttacgagaa acagaccaag taatccctac tggtaagaac tggaagatag cttcaccagg
    45361 caaccagagg aagtgattga cacctgccca aaactgagag gattctgtga tggtcttgcc
    45421 atccaacatc gaccaatgga caccttccaa gacattacgg aaaccgagga tcaatcctcc
    45481 gactatcaag gctggaataa tcggagtaaa aatctccgcc agagtggtca taacacgttg
    45541 gaccacgttt tgattactct tagctgcaga cttggctgct tctttggaaa caccctcaat
    45601 acctgaaacg gctgtaaaat cattataaaa gatgggcacg tcatttccaa tgattacctg
    45661 aaattgacct gcatttgtaa aagttccttt aacagctgga attgactcga tagctttaac
    45721 attagccttc ttatcatctc ctaaaacaaa gcgcatccgt gtcgcacagt gggtgacggc
    45781 agtcacattt tctttgcctc caattgcctg aagcagatct ttggcttctt gttcaaattt
    45841 tcccatttga ttctccttat acttgtcaaa gcaagtttga tttgataagt atattgtaaa
    45901 cgataccaaa cttgtctgca acttgtttgg tataaaaagg gtgttttttt gtaaattttc
    45961 tagcacttgt atggtaaaat agatacaggt gttcattaaa ctagactaaa aacctattta
    46021 agcaggcaaa atgaagaaat accaacaatt atttaagcaa atccaagaaa ccattcaaaa
    46081 cgagacttac gctgtcggag atttccttcc tagcgagcac gaccttatgg agcaatatca
    46141 agtgagtcgt gataccgtcc gaaaggccct gtctctcctc caagaggaag gattgatcaa
    46201 aaagataaga gggcaaggtt ctcaagtcgt caaagaagaa accgtcaatt tccctgtatc
    46261 caacctaacc agctaccaag aactagttaa agaacttgga ctgcgctcta aaaccaacgt
    46321 ggtcagtctg gacaagatta ttattgataa aaaatcctca ctgataaccg gtttcccaga
    46381 gtttcggatg gtttggaagg tggtccgcca gcgtgtggtg gatgatctgg tatccgttct
    46441 ggatacagac tatctggata tggaactaat tccaaatctc actcgccaaa ttgctgagca
    46501 gtctatctat tcttatatag aaaatggcct caaactcctt attgattatg ctcagaagga
    46561 aatcaccatt gaccactcaa gcgaccgaga caagattctc atggacattg gcaaagaccc
    46621 ttatgtcgtt tcgattaaat caaaagtcta tctccaagac ggacgccaat ttcagtttac
    46681 cgaaagtcgc cataagttag aaaaatttag atttgtagat tttgcaaaac gcaagaaata
    46741 aaagactgag acaccagatc tcagcctttt tcggctctat aatatttgta gtgggtaacc
    46801 ccctat
//
LOCUS       DAVMAH010000009        45554 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVMAH010000009 DAVMAH010000000
VERSION     DAVMAH010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45554
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.009"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            59..994
                     /locus_tag="VYO94_000454"
     CDS             59..994
                     /locus_tag="VYO94_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759145.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDEKFKDKATLETNVKEITKQIDFIKKVDETFKQENLEE
                     TLKSLNDLVDKYQKQIELLKKEEEKAAEKAKESSSQSNSSSGASNESYNGSSNSNVDY
                     SSSEQTNGYSNNYGSQSYSGSGDSSTNGGSSEQYSSSNSNSGVNNGYYKKYKNIGADG
                     HVSYTYDNESNGDVFDENWNYLGNTGGGIAEPPQR"
     gene            complement(1204..1281)
                     /locus_tag="VYO94_000455"
                     /pseudo
     CDS             complement(1204..1281)
                     /locus_tag="VYO94_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(1295..1972)
                     /locus_tag="VYO94_000456"
     CDS             complement(1295..1972)
                     /locus_tag="VYO94_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV1759146.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(1956..2495)
                     /locus_tag="VYO94_000457"
     CDS             complement(1956..2495)
                     /locus_tag="VYO94_000457"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV1759147.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(2507..3637)
                     /locus_tag="VYO94_000458"
     CDS             complement(2507..3637)
                     /locus_tag="VYO94_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV1759148.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(3705..4403)
                     /gene="dapD"
                     /locus_tag="VYO94_000459"
     CDS             complement(3705..4403)
                     /gene="dapD"
                     /locus_tag="VYO94_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV1759149.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(4633..5544)
                     /locus_tag="VYO94_000460"
     CDS             complement(4633..5544)
                     /locus_tag="VYO94_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1759150.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(5609..8071)
                     /locus_tag="VYO94_000461"
     CDS             complement(5609..8071)
                     /locus_tag="VYO94_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1759151.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMTKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNEHFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSRARR"
     gene            8213..9469
                     /locus_tag="VYO94_000462"
     CDS             8213..9469
                     /locus_tag="VYO94_000462"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV1759152.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(9547..11610)
                     /locus_tag="VYO94_000463"
     CDS             complement(9547..11610)
                     /locus_tag="VYO94_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1759153.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(11612..11890)
                     /locus_tag="VYO94_000464"
     CDS             complement(11612..11890)
                     /locus_tag="VYO94_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759154.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            12042..12890
                     /locus_tag="VYO94_000465"
     CDS             12042..12890
                     /locus_tag="VYO94_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1759155.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            13734..14261
                     /locus_tag="VYO94_000466"
     CDS             13734..14261
                     /locus_tag="VYO94_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759156.1"
                     /translation="MLIVSAIPSVSAVYASEQVSQIETNMELQPVTSLTEEQINTLAN
                     EIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGITVNQMGALLDTAIALA
                     LGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALEFAMNLLSPGTYLAQL
                     WDKNDAIPNNGRINF"
     gene            complement(15306..17564)
                     /gene="glgP"
                     /locus_tag="VYO94_000467"
     CDS             complement(15306..17564)
                     /gene="glgP"
                     /locus_tag="VYO94_000467"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV1759157.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGENSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(17590..19107)
                     /gene="malQ"
                     /locus_tag="VYO94_000468"
     CDS             complement(17590..19107)
                     /gene="malQ"
                     /locus_tag="VYO94_000468"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV1759158.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQFWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            19657..20928
                     /locus_tag="VYO94_000469"
     CDS             19657..20928
                     /locus_tag="VYO94_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1759159.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            21039..22331
                     /locus_tag="VYO94_000470"
     CDS             21039..22331
                     /locus_tag="VYO94_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1759160.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            22333..23175
                     /locus_tag="VYO94_000471"
     CDS             22333..23175
                     /locus_tag="VYO94_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1759161.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            23436..24236
                     /locus_tag="VYO94_000472"
     CDS             23436..24236
                     /locus_tag="VYO94_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV1759162.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PGQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            24246..25232
                     /locus_tag="VYO94_000473"
     CDS             24246..25232
                     /locus_tag="VYO94_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1759163.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNGNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            25299..25487
                     /locus_tag="VYO94_000474"
     CDS             25299..25487
                     /locus_tag="VYO94_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759164.1"
                     /translation="MRFNVGRFTSFSTEIESFSKIFLYSMKIKVQTRKLAAGCSKHCF
                     EVVDETDEVSNIPTARRR"
     gene            complement(25523..26464)
                     /locus_tag="VYO94_000475"
     CDS             complement(25523..26464)
                     /locus_tag="VYO94_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1759165.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(26442..28205)
                     /gene="aspS"
                     /locus_tag="VYO94_000476"
     CDS             complement(26442..28205)
                     /gene="aspS"
                     /locus_tag="VYO94_000476"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV1759166.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            complement(28511..28741)
                     /locus_tag="VYO94_000477"
     CDS             complement(28511..28741)
                     /locus_tag="VYO94_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759167.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(28759..29400)
                     /locus_tag="VYO94_000478"
     CDS             complement(28759..29400)
                     /locus_tag="VYO94_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1759168.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTFSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(29412..30146)
                     /locus_tag="VYO94_000479"
     CDS             complement(29412..30146)
                     /locus_tag="VYO94_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV1759169.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMLLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(30149..30346)
                     /locus_tag="VYO94_000480"
     CDS             complement(30149..30346)
                     /locus_tag="VYO94_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759170.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(30346..30552)
                     /locus_tag="VYO94_000481"
     CDS             complement(30346..30552)
                     /locus_tag="VYO94_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1759171.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(30562..30876)
                     /locus_tag="VYO94_000482"
     CDS             complement(30562..30876)
                     /locus_tag="VYO94_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759172.1"
                     /translation="MWVLVFILFIIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKKPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(31143..31223)
                     /locus_tag="VYO94_000483"
                     /pseudo
     CDS             complement(31143..31223)
                     /locus_tag="VYO94_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(31214..32503)
                     /locus_tag="VYO94_000484"
     CDS             complement(31214..32503)
                     /locus_tag="VYO94_000484"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV1759173.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(32581..33828)
                     /locus_tag="VYO94_000485"
                     /pseudo
     CDS             complement(32581..33828)
                     /locus_tag="VYO94_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
     gene            complement(34019..34870)
                     /gene="rgg"
                     /locus_tag="VYO94_000486"
     CDS             complement(34019..34870)
                     /gene="rgg"
                     /locus_tag="VYO94_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV1759174.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKGNETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            34994..35335
                     /locus_tag="VYO94_000487"
     CDS             34994..35335
                     /locus_tag="VYO94_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1759175.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            35393..35473
                     /locus_tag="VYO94_000488"
                     /pseudo
     CDS             35393..35473
                     /locus_tag="VYO94_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(35634..37337)
                     /gene="ilvD"
                     /locus_tag="VYO94_000489"
     CDS             complement(35634..37337)
                     /gene="ilvD"
                     /locus_tag="VYO94_000489"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV1759176.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(37570..38502)
                     /locus_tag="VYO94_000490"
     CDS             complement(37570..38502)
                     /locus_tag="VYO94_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV1759177.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(38499..39356)
                     /locus_tag="VYO94_000491"
     CDS             complement(38499..39356)
                     /locus_tag="VYO94_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1759178.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(39360..40706)
                     /locus_tag="VYO94_000492"
     CDS             complement(39360..40706)
                     /locus_tag="VYO94_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1759179.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(40719..41003)
                     /locus_tag="VYO94_000493"
     CDS             complement(40719..41003)
                     /locus_tag="VYO94_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1759180.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(41007..43037)
                     /locus_tag="VYO94_000494"
     CDS             complement(41007..43037)
                     /locus_tag="VYO94_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1759181.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            43228..44235
                     /locus_tag="VYO94_000495"
     CDS             43228..44235
                     /locus_tag="VYO94_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1759182.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            44238..44438
                     /locus_tag="VYO94_000496"
     CDS             44238..44438
                     /locus_tag="VYO94_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1759183.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            44590..44772
                     /gene="rpmF"
                     /locus_tag="VYO94_000497"
     CDS             44590..44772
                     /gene="rpmF"
                     /locus_tag="VYO94_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV1759184.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            44788..44937
                     /gene="rpmG"
                     /locus_tag="VYO94_000498"
     CDS             44788..44937
                     /gene="rpmG"
                     /locus_tag="VYO94_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1759185.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(45417..>45554)
                     /locus_tag="VYO94_000499"
     CDS             complement(45417..>45554)
                     /locus_tag="VYO94_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759186.1"
                     /translation="ESGSMATGWFTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
BASE COUNT        14228 a         9822 c         8188 g        13316 t
ORIGIN      
        1 aaagataggt gtaattttaa ttttaaagta attgcggaca ctatcaaagt aaaagattat
       61 ggagaacaaa tttgtagaat ttatcgaaaa caataaaaaa gtaatcattt catcagttgc
      121 agttggtgtt gtattggtat tagggtttgg atggtattca tataaccaac aacaagcaga
      181 acaacaagca aaaattgtac aattagaaaa agatagcaaa tcagacaaag aacaagttga
      241 taaactattt gaatcatttg atgcatcttc agatgaatct atttctaaat taaaagaact
      301 atctgaaact tcacttaaaa ccgatgcagg taaagactat cttaataaca aagtcaaaga
      361 atcatctaaa gcaattgtag attttcattt gcaaaaaggt ttggcttatg atgttaaaga
      421 ttctgatgag aagtttaaag ataaagcaac tcttgaaaca aatgtgaaag aaattacaaa
      481 acaaattgat tttatcaaaa aagttgatga aacttttaaa caagagaatt tggaagaaac
      541 tcttaaatct ctaaatgatc ttgttgataa atatcaaaaa caaatcgaac ttttgaagaa
      601 agaagaagaa aaagctgctg aaaaagcaaa ggaatcttct agtcaaagta attcttctag
      661 tggtgcttct aatgagtctt ataatggatc ttccaattca aatgtagatt atagttcatc
      721 tgaacaaact aatggatatt cgaataatta tggaagtcaa agttattctg gttctggaga
      781 tagttcaaca aatggtggat catcagaaca atattcatct agcaattcca acagcggagt
      841 aaataatggc tactataaaa aatataagaa tattggtgct gatggacatg taagttatac
      901 ttacgacaat gagagcaatg gagatgtgtt tgacgaaaat tggaattatc ttggaaacac
      961 tgggggaggc attgcagaac ctccacaacg ctaataacta ttttagagct gtgttgtttc
     1021 gaatggttcc aaaacacatt aaaagctact cattttttaa gtagcttttt tcttattcaa
     1081 gtttacatat tatactcttc gaaaatcaaa ttcaaaccac gtcagcgtcg ccttaccgta
     1141 tatatggtta ctgacttcgt cagtttcatc tacaacctca aaaccatgtt ttgagctgac
     1201 ttcgtcagtt ctatctacaa cctcaaagca gtgctttgag caacctgcgg ctagcttcct
     1261 agtttgctct ttgattttca ttgagtatta gtcgtcacat tcccattccc ttgtagaaaa
     1321 gcaaaatggc gagtcctacg aacaagacta ccgctcctaa tctctggctg gtgttataca
     1381 tccgtttttc tcctctaact ggaaagataa ctgctagaaa tgcgccacca actgcaccac
     1441 cgatatggcc tgctaggctg attcctggaa tcagaacact tccaataatg ttaaccacaa
     1501 aaagtgtcag ataggattgc cctagctgtt ggatataagg attgcgagtt gcatagcgaa
     1561 gaacaataat cgcggcaaat agcccataaa gagaggtaga ggcgcctgct gctaaggatt
     1621 taggactaaa tacaaaaaca aagagattgc ccatcattcc tgataagaga tagagaaaaa
     1681 agaactgctt agagccgaaa atctcctcta cctgccttcc aagataataa agtgaaagca
     1741 tattaacaat gaaatgttcc cacccaatat gaacaaaaat ggcagacaag agacgccaaa
     1801 cctgctcggg aaagaggcga atagctggcc catacatggc tccaaatcga aataatgtat
     1861 ctgccctgtc aaagtttccg cctgcagtga ccaacattag taaaaatacc aaggccgtca
     1921 ctaagaggaa gaaactcgtc acagggtaac gtctatcaaa gatttccttc atcaattaat
     1981 acctcctgaa caggaatatc atggttttca ggtataaagt cctgaatttg acaaggatga
     2041 accgtactca aagtacgacc agaaaaatgt tccagatagc ggtcataata acctccacca
     2101 tatccaatcc gatatccatc cgtcgtaaaa gccaggccag gaacatgaat caaatcaatc
     2161 tgagatacat ccaccacttc caaatctccc tgtggctcca gtaaggcaaa ggcagttttt
     2221 accaactgct gcggatcata gactacaaag tccatgcgcc ccttgggata agttttgggt
     2281 attaaaacct tcttgccgtc cttcagcgcc tgctcaatca gttcccgcgt ttgaaactca
     2341 tgagaaaaag agaggtaggt tgcgatgacc ttggcttctt gataaaaggg gtgttgtaaa
     2401 attcgctcgg ttaaagcttg gtctatagcc tgtttttgtt cttgagataa agccttcatt
     2461 tcatgcaaga cttgcttgcg taattccgat ttcatataca agccctctat tctgctgcct
     2521 tctttttcag gaaactagac accgcagcca ccccaatagc taagacttct tccttaggac
     2581 tcatttgagg gtgatgaaga gcgtagggac tatcgatacc tagccaaaac atcacgccat
     2641 caacctttga aaggagataa ccaaagtcct cgcctgtcat agcaggttcg atatcaatca
     2701 actcgattcc gtctttttcg tcaaagaagt ccatcagttc acgcgccaag gctggattgt
     2761 tctcaacagg taggtatcca ccttgtttga gttccacttc gacttccata tcaaaggcag
     2821 ctgcaacccc ttctgcaact gtttttaccc tcttttgcac caagagactc atgtcctgtg
     2881 tcaaggcacg aatagttcca tgtaaaaaag ctgtgtctgt gatgacattg ttggtggttc
     2941 cagcttgaaa aacgccgaag gtcaccactg ctccctcgat tgggttgaca ttgcggctaa
     3001 caactgactg cacttgggtc acaaagtaac tagccgccac caaggcgtca ttggcttcat
     3061 gaggaaaagc tgcgtggcca cctttgcctt tgaaacggat cttcacctcg caagttcctg
     3121 caaagagtgt atgagtatta gtcgcaatct ggccgacttt caaatctgga cgaacatgga
     3181 gaccatagaa ttggtttggc aaccaatctc caaaagcacc gtcctcatac atgagcatac
     3241 caccagcttc attttcttca gcaggctgaa atagaaagag cagattattc ttgggttgct
     3301 cctcaagggc gcgctcaaga cagcctaagg caatggtcat atgaaaatca tgaccacagg
     3361 catgcatgcg accttggtgt tgagaagcaa aaggtagacc tgtttgttcg acgataggca
     3421 ggccatcaat atctgtccgc caaccaatgg ttcgctccgg ctgacttccc tgcaggtaga
     3481 ccaaaatccc tgtccgccaa gtacgaattt gaacaaaatc cttgcccgta gtcaatttct
     3541 caatcacatc cagcaaataa gcctgagtct tgaactcctc caagccaatc tctggtatct
     3601 ggtgtaaatc tcgtctagtc tgaatcaaat ctaacatcta tctgtcctcc gatatagcag
     3661 aaagaggctg gaaaaagggt tccgcctctt ttttactttt acaattacaa ggtacgaagc
     3721 gcatcctcta gcgctgtttt ttgttgagtt tgggcatcaa tttctttgat aatacgagct
     3781 ggaacacctg ctactaccac gttttctggg acatcttggg taacaatagc tcctgctgcg
     3841 acaactgaac cactaccgat ttggactcct tcgataacca ctgcattagc accgataaga
     3901 acattgtctc cgacacggac tggttcagca ctagctggct caatcacacc tgccaaaact
     3961 gcacctgcac caacgtggct attttttcca acgatagcac ggccaccaag gatggcaccc
     4021 atgtcaatca tggttccagc accgatttca gcaccgatat tgataacagc tcccatcatg
     4081 ataacagcat tgtcaccaat ttccacctgg tcacggataa tagcacctgg ctcgatacga
     4141 gcgttgatag cacgcttatc tagcaaagga actgcagaat tacgagcatc ttgctcgaca
     4201 acataatctt gattttctac caaaccttca agaagcggag ccacgtcctt ccagtctccg
     4261 aataggacat ttcctagttt gacaacagag ctaggcacag cagttgcgag ttgcccctca
     4321 aaggttactt tgacactggt tttcttttca gcattggcga taaattggat aatttcttga
     4381 gcgttcattt ttgtagcagt cataggtgcc tcctggttcg ttataatgat acctattcta
     4441 ccaaaaaagg cctcaaattt gaaacctttt tgtctgtttt taggtatgat tttttagggt
     4501 tgtgagataa aacgtgctgt cggtaaaagc aagcccctac cgatacaacc taaaaacact
     4561 cttcacaact atctccccgt gttttattga ctattctagt atagcacact tttagaatta
     4621 agaaaagact ttttatctac tttctttcgc ttcttctata gacaaaaata tcatgggtaa
     4681 aataatcaag gctatagcta gaaggaggga ccaatccact actaatccta agaacaaaac
     4741 actcaagaga gcagaagaga gaggttcact ggcactgata acggaaacca ccaaaggaga
     4801 aaccaaggac acagccttca tggaaatgaa aaaagcaaaa gccgttccaa agaaagcgat
     4861 aatgaggcaa atcaagatac tccaaatatc aagagtaaag gaaagctgat aaaccggcga
     4921 gaggacattg ctaaacaaac ctgccaaaat catcccccac ccaaccgtag gaacaaaacc
     4981 ataacgctta gcaaaaggtt ggggcaagat aacattaaac ataacaccca tggcactcag
     5041 caaacctgtt ataagagcta gcggcgtcat ggataactga gagagatctc cctttgtcgc
     5101 catcaagcaa acacccagca tggcaaccaa aacatagaaa acagcgcttt ttgacgctcg
     5161 tttttgataa accaagcgat tataaaagag gataaagaca gggctaataa actgtaaaat
     5221 agttgctgtc gtagcatttg agtattctac acagagatag aaaaaatact gaactgaaaa
     5281 aatccccaaa atagcatagg ctaaaaaggg caggtaattt ttcttgtctc gccaaatatc
     5341 tagcacttgc gattttaatt gtattgcaga ccaaatgagt acaagactcc ctgccagtgt
     5401 caaacgcata gaggtaatcc agcccgaaga cacctgataa tgagtaaaga agtactctcc
     5461 taaaattcca cagattcccc atattaagcc ggataggagc gaataaattt ttccgttaac
     5521 aatctttttc tgatactgat tcataccctt attgtaacac gaaaggaaaa aagtggcaat
     5581 ccattgattg gccacttcat ttagagaatt atcgtctcgc ccttgaagaa ggtcgtgtag
     5641 tacttgagtt actgctatcg ctagaactac tacttgaact gctggagctg gatggagttg
     5701 gtagactccc cacaatacta gaccaagcat tctgataatc cgcatcactt ccaccaatag
     5761 caaagcgata acttgtcgct ggcgctcctg acttattagc ccaatagctg gtaacagtcg
     5821 aacctgtgac ctctacttct tttccttcaa cagaaacctt ccctggtttt tgacctgttg
     5881 atttcaagac ttccgatttc actacactag gatctaaagc aaagtgctcg ttcccccaaa
     5941 tgcttgggga agcttgctga atcgcattta ctagatgagc catgtaatta gagttattag
     6001 aataacctgc tctacgtgac aatgaatgat tatcatcatg cccaatccag ccacctaggg
     6061 ttaatctagg tgtcgaaagc atgagccaca tattttcgtc ttggttggtt gtaccagtct
     6121 tcccaatcca atctgcatta gccagagtag gatttaaaga agtcaggtta gacttgaagg
     6181 ttgttgtcac acgagaggat agaacttctc gtagcaatcc ctgcataatc gtcgcagtag
     6241 cttttgaata gacttgaact ggtttatcct gatactcata caccactcta ccatctgctg
     6301 cttcaatctt tgaaatcaca tgcttctgat gataaactcc attattagct aaggtctgat
     6361 agccattggt atgctgggca actgtgactt caataccacc acccattggc aagctctcaa
     6421 taccgtactc aggaatctcg taacccatct tttccatata acccttgaca tcaacaccct
     6481 tttcacggag catacgatag gtccagtaag cagggatatt ccatgaatag ttcagagctt
     6541 ctcccaaggt catcattcct gttcccttgc tattagcata cataatcgga ttgccattag
     6601 caaagtttgt tggatagtta gatagaatcg tttcacttcc catcaagccc tggtcaatag
     6661 caataccgta ggccagcaag ggcttggtag tagaagctgg cgaacgtttg gtatcaaagg
     6721 catgattatt ttgattttct tgataattac gaccacctac aaagcctaga atagcacctg
     6781 tttggttgtc catcaagaca ttccctactt ctacacgacc tgttccatcg tctaaaagat
     6841 agccataatc agcaaccgca ctttgcatgg cagaatgaat tttctgatct atggtagtag
     6901 taatcttata accaccattt tcaatttcct tggctgccaa atctcgataa aacttctgag
     6961 ttgcctcatt tttcaactcc ttagcggaga cattgtctct ctgagctaga tagtcataca
     7021 tacgttcttg agcttctgcc aaagttgtaa agtataaata gtctcgtgaa attcctgtga
     7081 ccgtgcccga tggtaaaaag tcctgtttaa ggtcataatc cttgtactga gaatactcgt
     7141 ctttgcttaa tgcacctgta cgatacatac tgtaaagaac tgccttagcc cgtcttaagc
     7201 caatttctag gtcttcatca ctcttcaact ccccagtatt ttcataagga gagtaagtaa
     7261 taggactctg tggaagtcct gctaaaaatg ctgcttgagg aacagtcaac tgactggcat
     7321 ctacaccgaa aattccctca gctgcttgcc gagcccctgc aatattctgt cccttattat
     7381 ttcggccaaa gggagccaca ttgagatagg tcgttaaaat ctcatcttta gtcatggcgc
     7441 gttccaaggc aagagcatcc acaatctctg ccgccttacg agccaaggtc ggcgcatccc
     7501 caaccacctg ctgtttaatt agttgctggg tcaaggttga acccccacta gaggaaccca
     7561 aacctacaaa tttccccaag gtcgcacgaa tcaccgcctt gggtactaca cccttatgtt
     7621 ctttaaagtg ttcatcttct gtcgcaatga tagccttctt cagattttcc gaaatttgct
     7681 cagatgagat agaagtgcgc aacaaatcac tctctatgga agcaatcacc gtcccgtccg
     7741 aataggtaat ctctgaaata gaagagatgt ccttgacctg attcaccaat tcttctgtct
     7801 gaggcacccg aaccttgtca aataaggcca ctccgtaccc caaagcaatc ccagctccca
     7861 acattcctcc tagaaaaccg agtacaaaga gtaagttaaa taaggctttt atactcagta
     7921 aaatagctgg gaaaatggct gacttatcta aggttttaga ttttttggta cttgaacctt
     7981 tcttgccagg tctagctgat tttttatttt tttgtttttg ctggaaaaat tccagcattt
     8041 ttcgttttaa ttcatttaat tgattttgca tggatttcct cactttatct attataccac
     8101 aaaagggaaa ttttcaataa aatagccact ttcttcccta ttctgctagg ctattgccca
     8161 agtttgtgat acaataggta gaaacaataa ttttaaaaag gagaaaagac acatgcacat
     8221 ttttgatgag ctaaaagagc gtggtttgat atttcaaacg actgatgaag aagctttgcg
     8281 taaagcccta gaagaaggtc aagtttctta ttatactggc tacgatccaa ctgctgacag
     8341 ccttcaccta ggccaccttg tcgcaatctt gacaagtcgt cgcttgcaac tagcaggtca
     8401 caaaccttat gcgctcgttg gcggtgctac aggtctcatc ggagatccgt ccttcaaaga
     8461 tgctgaacgt agtctccaaa caaaagacac agtagatggc tgggtcaagt ctatccaagg
     8521 acaactttct cgttttcttg actttgaaaa tggcgaaaac aaggctgtca tggtcaacaa
     8581 ctacgactgg tttggcagca tcagcttcat tgacttcctc cgtgatattg gaaaatactt
     8641 cacggtcaac tacatgatga gtaaggaatc tgttaaaaaa cggatcgaaa caggaatttc
     8701 ttacactgag ttcgcttacc aaatcatgca agggtacgac ttcttcgtcc ttaaccaaga
     8761 ccataatgtc actcttcaaa tcggtggttc tgaccagtgg ggaaatatga cagctggtac
     8821 cgaattgctt cgtcgtaagg cggacaagac tggtcacgtt atcactgttc cactaatcac
     8881 agatgcaact ggtaaaaaat ttggtaaatc agaaggaaat gccgtctggc tcaatcccga
     8941 aaagacttct ccatacgaaa tgtaccaatt ctggatgaac gtgatggacg ctgacgctgt
     9001 tcgcttcttg aaaatcttta ctttcttgtc acttgatgag attgaagata ttcgtaaaca
     9061 atttgaagca gcgccacacg aacgcttggc tcaaaaagtc ttggctcgtg aagttgttac
     9121 acttgttcac ggagaagaag cctacaaaga agcacttaac atcactgagc aactctttgc
     9181 aggaaacatc aaaaaccttt ctgtcaaaga gctcaaacaa ggacttcgtg gtgtgccaaa
     9241 ctaccaagta caggcagacg aaaacaacaa tatcgtggaa ctgctcgtct catctggtat
     9301 agttaactca aaacgccaag cccgtgaaga cgtccaaaac ggagccatct acgtaaacgg
     9361 cgaccgcatc caagaccttg actatgtctt gagtgacgct gataagttag aaaatgaact
     9421 gactgttatc cgtcgtggga agaaaaaata ctttgtattg acttactaaa ctattcaaca
     9481 tttatctata aacaaaggag ttaacctcga gaaaggtaac tcctttttgc tgttaataac
     9541 tctcatctat ctatttttaa tagacaggct acgcaggaca atgcgcaagg ttgttagatt
     9601 atgtaagata gagagatttg aaggactgag ccaattaaat aagccgaagc caatcaaact
     9661 actatttacg acaacggtat cttgaatatt tttcttgatg agtgtttgca aagatgatga
     9721 taacgaatcc aactcttgga agaaatccaa acgattatct aacaataaga tatcactcat
     9781 ctgcttagaa atatctgcac tctcattcat caccacaccg atatctgata gagttaaagc
     9841 cgctgagtca ttcaatccat ctccaaccat caaaatagtg tgacctgctt tctgcagttt
     9901 ctctactaac tcaaatttcc catcaggttt caagtctgta tagacctgat caaagggcaa
     9961 atctttgact aattcctctg tcctaatcaa ggtgtctcct gttgccagaa tcaatttttt
    10021 cccctgtgcc ttaagtttat ccaaggctgt ttttgcttct tttctcaaag gagtatgaat
    10081 gcagaacatt ccaatcaatt cattttgata agccaagaat aagagattgt agtgactctt
    10141 gtactcttca attaaagcat tttgttctga actgatatga atctgctcat cctgcatcaa
    10201 gacataattc ccaataagaa ctggttggcc atctatatga gatttgatcc ccttgcttgc
    10261 gatatattgg agtttcccat gcatttcctc atgttcaatt ccctctatct cagcttgctt
    10321 gacgatggca ttagcaatag gatgataaat gtgttcctca agacaggcac tgattctgag
    10381 aatatcttcc tcactatagt ctccaaaagg taacaccttt tcaactatag gataactagt
    10441 tgtgattgtt cctgtcttat caaacaagaa agtatcaact tccagatatt tctccagaac
    10501 atctccatcc ttaatcacca tttcacggtt caacccttcc ttgataactg tcaaataagc
    10561 tacaggagta gagattttca aagcgcagga gaaatcgacc aataggaaag aaatagcctt
    10621 agaaaaagaa cctgtcaata ggtaagtcag cccagccccc aagaaattat atttgacgac
    10681 tttatccgcc atcttgatga aatagcgttg tttcgttttc ttgttttctt cagatttctt
    10741 catcaactca atcagctgta aaatacggct gttcatctga ttatctgtta cacgaatgcg
    10801 taactctcca gtttctaata ctgtatttgc acaaactaaa tcagactctc ttttttcaac
    10861 tggaaaactc tctcctgtca aggaactttc gttgaccata cctaaacctg aaactacttg
    10921 tccatcaaac agaatttcat ttccttgaga taagatcaag acatctccta tttgaacatc
    10981 ggaactcttg atactaacaa ccgtatcgcc ctgtactagg aatacatcgc tctcttttgc
    11041 aagaagactc tgttctaaat ctgttgcagt ttttttcaag gaccactgat ctaaatgatt
    11101 ccccaaatca agcataaaca tgatattgct agctgtcttg gattggttca taaacaaaga
    11161 caataaaata gccgaacagt ccaagacttc catcgttagt tccttacgcg ctagtgtttg
    11221 ataggcttct ctaatataac ccaaagcctg ataacaagtc catatatagc gaataggata
    11281 cggcacaaaa ctacgaaaaa gtacacgctt aaccgctgca cctgaaacaa tagaataagc
    11341 actctcttct ctacgaatgg gaagagtcat caactcagaa actttccctt tatcaattct
    11401 ttttaaaaag gcttctgcat tatctaatac agaaaagcct tcttttatgc gtagagtaaa
    11461 gtgctgttga tccatgtaaa actggataga ctcaatcccc ttttcatctc tcgccaagga
    11521 acgaagatag tcttgaatat ccaaggtaag tgaaaaagaa gatgatagtc ggatatgttg
    11581 gtatcctcta tgtagcactt taaaagacat attattcacc tataaggcta tctaattgct
    11641 cttctttttt ctcttgctcg tacaaatatt tggcatcttg caagacatcg tctccatgtt
    11701 gcttcacaac agaaacagat gcatctagct cgtctttcaa cttgtaagcc ttagccaaag
    11761 ctttagaata acctttttta gcttccttac ttgctaagat tttcaaacca agggtaccaa
    11821 atgcgacacc acccaaaaat aatgaagatt ttttcgcaac ttttgcaacg gttaatactt
    11881 cttttaacat acttatttcc tccttatcat tattatatag caatttagat ataaaagcaa
    11941 tttcattcta taaattggag aattagtttt atttctactg aatctcccat ctacttattc
    12001 ctaaagttgc tttcatttgc ctcttttgat acacttaaac tatgaataca aatctcaagc
    12061 ccaaacttca gcgttttgct tctgcgactg cctttgcctg tcctatctgt caagaaaatc
    12121 tgactctgtt agagactaat ttcaagtgct gcaaccgtca ttcttttgac ttggcgaaat
    12181 ttggctatgt caatctagca cctcaaatca agcaatctgc taactatgac aaggaaaatt
    12241 ttcaaaaccg tcaacaaatc ctagaagccg gcttttacca agctatctta gatgctgtat
    12301 ctgacttgct tgcaagctca aaaactacca caacaatttt ggatatcggt tgtggtgaag
    12361 gattctattc tcgcaaacta caagaaagtc actctgaaaa aactttctat gcctttgaca
    12421 tctccaaaga ttcagtccaa atcgctgcta aaagtgaacc caactgggca gtcaattggt
    12481 tcgttggcga cttggcacgc cttcctataa aagacgctaa catggatatt ctgcttgata
    12541 tcttctcacc tgccaactat ggagaatttc gtcgcgtttt atccaaagac ggtatcttga
    12601 taaaggttat cccaactgaa aatcacctca aagaaatccg tcaaagagta caggaccagc
    12661 tgacaaacaa ggagtattct aaccaagata tcaaggagca tttccaggaa cactttacca
    12721 tcctatctag tcaaactgcc tctctgacta agactatcac agcagaacaa ctccaagccc
    12781 tactcagtat gactcctctc ctctttcacg ttgaccagag caagattgac tggagccaac
    12841 tgacagagat taccatcgaa gcagagattc tggttgggaa agcattctaa tactcttcaa
    12901 accacgtcaa cgtcgccttg ccgtacgtat ggttactgac ttcgtcagtt tcatctacaa
    12961 cctcaaaacc atgttttgag ctgacttcgt cagttttatc tgcaacctca aagctgtact
    13021 ttgagcaacc tacggctagt ttactctttg attttcattg agtataaact agacttcgca
    13081 aaagtagaaa acttaccgaa aatcttcaat atgacaaaaa cgtataagaa caggtacaca
    13141 aaccttaatc ttatgcgttt tgttatagtt tccatacgca ttaaggggaa atagttgaaa
    13201 tcagttcttt taataaccat tgaataccat atactacatt taccccaaat atgatatagg
    13261 ccgtataaat caagtatttc gatttttccc gcctcaaaga atagatctta tacaaaataa
    13321 ataaatttaa aataataaat aatagagaca aaatcttcct ccaaaatcaa tcctaaaagt
    13381 acacagtcaa gcatagctct aatctttatt ttcgattcga aattacaaac ttatcaatga
    13441 acaataagtg atataaggtc agtaccaaac cccaaaagct accacgaaaa gagaattctt
    13501 gatgattgag agtaaacaaa tcatggttac caatatagag gcaggtcaaa ataacaaata
    13561 aaatccaaaa taaatccgtc catttatatt ttgaaaaata tttttttaac ataatagcat
    13621 atttttcttg actataataa cagtatataa taaaatgtaa gcagatacaa ataaaaagga
    13681 gaaaagctca tgaacaaatt aatgaaattt atttcggttt tttgacgtca attgtgttaa
    13741 ttgtatcagc gattccaagt gtttcagctg tatacgcttc tgaacaagta tcgcaaattg
    13801 aaacaaatat ggaacttcaa cctgtcactt ctctaacaga agaacaaatc aatacacttg
    13861 caaacgaaat ccaatctttt catccagacg tctcacaaca atggatcaaa gaagtaatta
    13921 accgacaatt acaaggcgat tatacaatcc cacctacata ctctccattt agagcagctt
    13981 ggcaaggtat tacagttaat caaatgggtg ctctattaga tactgcaata gctttagcct
    14041 taggaggaac tactgcaggc cttgcaaatc taattaaagt aaaaggaaaa catgcagcaa
    14101 aaagtgctat tcgttcagca atttctagat atctaggtag ttggtttgta aatgatgttg
    14161 ctttagaatt cgctatgaat ttattatcac cggggactta tttagcacaa ttatgggata
    14221 aaaatgatgc cattcctaac aacggaagga ttaactttta atcatgagat atacaataaa
    14281 attaattggg tataacgtat tttcgttgtt tatattcttt atcttatcaa tgttgtttaa
    14341 agttcccttt aggtggtgga tcagcattgc aatgacgact tcgtcgtaca ttgtatataa
    14401 ttacttaaag aaaaagagag aaaaggaatg atcttatacc agatcattcc ttttctgctt
    14461 tctgtaaatc cctcggagtg tgtttggcgc tttgatacga agtgtcaaag ctgtataaac
    14521 gttactattt ccaaaaaagt aacagaaaat tcctgctttg taggactgct ttgggtgagt
    14581 aatagacatg tcgactcacc ctatctcctg atggcgaaaa gaatttagca atgatgcaag
    14641 ttgttctgaa ctcgagaaaa aacatgccga aatcgaagaa aagcgtgcag aacttgaagc
    14701 gaagaagcaa gaaatgttga agcgcttgga taaatagaat ttagaaaaca gaaaaaacta
    14761 aaaagaatgt agggtttatt tccctacatt cttaaaataa cttagtacat aaatgacaat
    14821 gctgccactg ccgtcaatat tgcaaaaact attttccaaa tttttttatt ttttccaaaa
    14881 atcttatcag gtaacaagct tattacaaga aaggtaataa acaacaccaa tttaagtgtg
    14941 tatatcataa aaacaccttc tttcctacaa ttatattata atactttatg taagcgaata
    15001 caagagatat gaggtaacca actacgaaaa aatataaggc tgaagacagt aaaaaccagc
    15061 atttaaagcc ttcactgtat ctaggatttc cctattttta gacaagattg acccaaatcc
    15121 acagcattta aaaaagcgaa tttcaatcga aactcgcttt tttacaagat gtattagtat
    15181 aaatttgtat cttatactca atgaaaatca aagagcaaac taggaagcta gccgcaggtt
    15241 gctcaaagca ccgctttgag gttgcagata aagctgacgt ggtttgaaga gattttcgaa
    15301 gagtattagt tcaagtgcca gatgtcttcg ttatactgag cgattgtacg gtcagatgag
    15361 aagaatcctg ctttagaaat gttaacgatg actttatcca accatgcgtc acggtcttcg
    15421 tagtcagcaa gcatttgctc tttgactttg atgtagtctt ccaaatcaag aagagtcatg
    15481 aaccagtctt tgttgatcaa ttcattgtaa agacgttcca agcgctcttt gtttccagct
    15541 gcaagaactg catcactaac gatgaagtca accaatggtt tgatagcttc acgagcgtag
    15601 aattcgcttg atttgtaagc tgcttttgcg taaaggtcga taacagtttc tgaattttca
    15661 ccgaagatgt agatgttttc ttctccaacc aactcagcga tttccacgtt agcaccgtcc
    15721 atagtaccaa gtgtcaaagc tccgttcaac atgaatttca tgttaccagt acctgaagct
    15781 tctttagaag caagtgagat ttgttctgag atatcacatg ctgggataag gaaacttgct
    15841 gcagtaacgt tgtagttttc aaccataact acttgcaagt gtggagctac tgctggatcg
    15901 ttagcaataa cttctgacat gcaaaggatt aaatggataa tgtcttgagc gattgtgtag
    15961 gctggagctg ctttaccacc aaagaagatt gtgattggac gagcagggat gttaccagct
    16021 ttgatgtcaa ggtatttgtg gatcacgtac aaagcgttca tttgttggcg tttgtactcg
    16081 tgaagacgtt tgatttggat atcaaagata gaatttggat tgatttccac accttggtgt
    16141 tctttcaagt gacgagccaa tttacgtttg ttgtgagcct tgatgctttc caatttttct
    16201 ttgacagctg ctttgtcttc ataagacaac agtttttcaa gctcatctgc ttcatggtgc
    16261 caaccatctc caagaatctc atccaagtag tgagacaatc ttgggttagc atgcataagc
    16321 caacgacgga aagtgatacc gtttgttttg ttgttgaact tttctgggta aaggtcgtag
    16381 aaggctttca actcagaatt tttcaagatt tcagtatgga gtgctgcaac cccgttaaca
    16441 ctgtatccgt agtggatatc catgtgagcc atgtgaacac gtccgctctc atcgatgatt
    16501 tgaacagctg gatctttgta ctctgccttc acacgacggt ccaattcttc gatgattggt
    16561 accaagtgag gaaccacttc ttgcaagaat tcaagaggcc atttttcaag cgcttcagca
    16621 aggattgtgt ggttagtgta ggcagtcatg ctacgaacaa ttgagattgc ttcgtcaaga
    16681 tcgataccac gtgcagtcaa aagacgaatc aattcaggaa tcaccattga tgggtgagta
    16741 tcgttgattt ggacaactgc gtagtcagca aggtcatgca agttgcttcc tttttcgatt
    16801 gcttcgtcga tgatcaattg cgcaccgttt gaaaccatga agtattgttg gaagatacgg
    16861 agcaattcac cttgacggtc actatcatct gggtaaagga agagagttaa gttgcgagcg
    16921 atatctgtct tgtcaaagtt gataccatct ttaataatag aagaatcaac tgaatccaag
    16981 tcaaacaaac gcaagcggtt tttagtcgct gtttcataac cagtaacatc aatatcgtaa
    17041 agagttgatg tcaaagtaaa gtctgcaaat ggtacttggt agctacggct tgagcgaacc
    17101 aaccagtttt gctctgtcaa ccatgcattt ggaattgttt cttgttggtt gtttttaaga
    17161 acttgttgga aaagaccaaa gtggtagtta agaccaacac cgtcaccatt caaaccaaga
    17221 gtagcaattg agtcgataaa gcaggcagcc aaacgtccca aaccaccatt accaagagat
    17281 ggttccaatt caacttcttc aacttcgatc aagtctttac ctgcagctgc aagttctttt
    17341 ttaacatcgt cgtaaagacc aaggttaatc aagttgtttg acaagagttt accaatcaag
    17401 aactcagctg agatgtagta aacttttttc ttaccagtgt tgactggttt ttggctgctt
    17461 gcaagcttgc tgtagttaag aagagcaagg taaagctctt cattgctaca ttctgcaatg
    17521 gttttattgt aacgattttg tacaaattct tgtagtgata acatgtttag ttgtctcctg
    17581 attattgtct tatttcttta aatctaccaa attttcatta attcggcgat aaattgttgt
    17641 caagtcaagc aaaccttcct cgacagctgg tgtcaattga tcttcagtca tacgccaaga
    17701 ccagtttcca ccaagggtag atgggaagtt catacgagct gcctcatcca attctagtaa
    17761 atcttgcata gttgcaattg ccataaagct aactgatgaa aatactgtac gaagcatagc
    17821 gtgtaccact gtttcgtatt ctttacggtt cgtgtaacga gccatgtact cacgagtcgc
    17881 atcatcaatc tcattacggt accaaccaag aaccgtattg ttatcgtgtg ttcctgtgta
    17941 cataactgag ttagcaggtg ccaagtgtgg gctatcaatg ctttcgtctt ctgggttgaa
    18001 ggcaaattga agaatcttca ttcctgggaa gccagtacgt tcacgcaatt cgatcacttc
    18061 atctgtcatg aagccaaggt cttctgcgat gatgtttagc tcaccaagtt cttccttaac
    18121 ggctgcaaaa agcttgtagc ctggaccttt cacccactca ccaggtgctg ctgtatcgga
    18181 accagcaggg atttcccagt aagattcgaa gccacggaag tggtcgatac gaacgatatc
    18241 gtagattttg aagctttcac gcaagcgttc aatccaccat ttgtagccgt ctttgtccat
    18301 tgcttcccag tcatagattg ggttacccca aaactgacca gttacagaaa actcatctgg
    18361 tgggcatcct gcgatacaag tagccttacc attgacatct gttttgaaga gatgtggatt
    18421 tgcccacata tcacttgaat cttccgctac gtagattggc atgtccccaa cgatttcgat
    18481 gtggttgtcg ttagcgtaag ctttcaattt caaccattgt tggaagaaga agtattgagt
    18541 cacacggtgg taaaccaact tgtctgccaa ttgctcacga tagctttcaa gtgctgaagc
    18601 tttacgagca cgagcatctg catctggcca ttcagtccaa gcaagattgt caaaatactc
    18661 tttgatagcc atatactcag caaagagctc aagccatgat tggttgtctt gagcaaattt
    18721 ctcaaaatct ttaacatctc cgacttcaaa gaaacgtttc accgcttttt ctaaaagagg
    18781 acgacgtgca tagtagattt tagcatagtc aacttcagac gcatcgctac caaagtcaac
    18841 tccttcaagg tcacttgctt ccaacaaacc ttgctccacc aagatatcta aatcgataaa
    18901 atgagtgttt cctgcgaagg ctgagaaaga ttggtaagga gaatccccgt aactagttgc
    18961 tcctaatgga aggatttgcc agtaacgttg ttttgtacgg accaagaaat caacgaagtc
    19021 gtaagcactt tgaccaaatg atccgattcc gtaagctcct ggaagagaag agatgtgcat
    19081 caacacacca ctttgacgtt ttttcataat agcacctcgt gtgttaaaat aatggaacgt
    19141 tgcgtatttt gcagacgcaa acgtttgcgt tacttataag tatactcctt ttcaagcata
    19201 attgcaagcg tttttaaaaa acttttttga ttatttttaa ggagactaac tcattttagc
    19261 aaagataact taaaactatc taatcctaag gtttgactct cacgagacag tctacaaagt
    19321 acaaaacctc cttagggagc ttgaatttat atgtaacaaa gcacaaacgt ccatagaaaa
    19381 tagataggga ttagaaccag ggaggtagcc cctcctggtt tccctcttta gacagattcc
    19441 atatattttt attaaaaata ctgtattctt atctatttca tacttttctt ctattaaaat
    19501 gcaaaattat gctatcaaat caagcttaaa aattttttaa aatttttaca aaaaatactt
    19561 gcaaccgttt tctatttgtg ctatactaag ctcataaagg aaaacgtttg cgtttcctta
    19621 tcaataaaac ttgctattct ttgggaggaa tacactatgt catctaaatt tatgaagagc
    19681 actgcggtgc ttggaactgt tacacttgct agcttgcttt tggtagcttg cggaagcaaa
    19741 actgctgata agcctgctga ttctggttca tctgaagtca aagaactcac tgtatatgta
    19801 gacgagggat ataagagcta tattgaagag gttgctaaag cttatgaaaa agaagctgga
    19861 gtaaaagtca ctcttaaaac tggtgatgct ctaggaggtc ttgataaact ttctcttgac
    19921 aaccaatctg gtaatgtccc tgatgttatg atggctccat acgaccgtgt aggtagcctt
    19981 ggttctgacg gacaactttc agaagtgaaa ttgagcgatg gtgctaaaac agacgacaca
    20041 actaaatctc ttgtaacagc tgctaatggt aaagtttacg gtgctcctgc cgttatcgag
    20101 tcacttgtta tgtactacaa caaagacttg gtgaaagatg ctccaaaaac atttgctgac
    20161 ttggaaaacc ttgctaaaga tagcaaatac gcattcgctg gtgaagatgg taaaactact
    20221 gccttcctag ctgactggac aaacttctac tatacatatg gacttcttgc cggtaacggt
    20281 gcttacgtct ttggccaaaa cggtaaagac gctaaagaca tcggtcttgc aaacgacggt
    20341 tctatcgcag gtatcaacta cgctaaatct tggtacgaaa aatggcctaa aggtatgcaa
    20401 gatacagaag gtgctggaaa cttaatccaa actcaattcc aagaaggtaa aacagctgct
    20461 atcatcgacg gaccttggaa agctcaagcc tttaaagatg ctaaagtaaa ctacggagtt
    20521 gcaactatcc caactcttcc aaatggaaaa gaatatgctg cattcggtgg tggtaaagct
    20581 tgggtcattc ctcaagccgt taagaacctt gaagcttctc aaaaatttgt agacttcctt
    20641 gttgcaactg aacaacaaaa agtattatat gataagacta acgaaatccc agctaatact
    20701 gaggctcgtt catacgctga aggtaaaaac gatgagttga caacagctgt tatcaaacag
    20761 ttcaagaaca ctcaaccact gccaaacatc tctcaaatgt ctgcagtttg ggatccagcg
    20821 aaaaatatgc tctttgatgc tgtaagtggt caaaaagatg ctaaaacagc tgctaacgat
    20881 gctgtaacat tgatcaaaga aacaatcaaa caaaaatttg gtgaataaaa aatttgttca
    20941 aggggggtgg aaatcaaatc cccctttgaa tttatcaata gagacacaaa taatttagct
    21001 ttcttataaa aaagtagtat cctatgaaag gagttaatat ggaaaagcaa caacctagta
    21061 aagcagccct gctgtctatc attcctgggt taggacagat ttacaataaa caaaaagcca
    21121 aaggttttat cttccttggt gtaaccatcg tatttgtcct ttacttccta gcacttgcaa
    21181 cccctgaatt gagcaacctc atcactcttg gtgacaaacc aggtcgtgat aattccctct
    21241 ttatgctgat tcgtggtgcc ttccatctaa tctttgtaat cgtttatgta ctcttttatt
    21301 tctcaaatat caaagatgca catacgattg caaaacgcat taacaatgga attccagttc
    21361 cacgcacact caaagacatg atcaaaggga tttatgaaaa tggcttccct tacctcttga
    21421 tcattccatc ttatgttgcc atgaccttcg cgattatctt cccagttatc gtaaccttga
    21481 tgatcgcctt taccaactac gacttccaac acttgccacc aaacaagttg ttggactggg
    21541 ttggtttgac caactttaca aacatttgga gcttgagtac cttccgttct gcctttggtt
    21601 ctgttctttc ttggactatc atttgggctt tggcagcttc tactttacaa atcgtaattg
    21661 gtatcttcac agctatcatt gccaaccaac catttatcaa aggaaaacgt atctttggtg
    21721 ttattttcct tcttccttgg gctgtcccag ccttcatcac tatcttgaca ttctcaaaca
    21781 tgtttaacga tagtgtcggt gctatcaaca ctcaagtatt gccaatcttg gctaaattcc
    21841 ttcctttcct tgatggagct cttattcctt ggaaaacaga cccaacttgg actaagattg
    21901 ccttgattat gatgcaaggt tggctcggat tcccatacat ctacgttttg actttgggta
    21961 tcttgcaatc tattcctaac gacctttacg aagcagctta tattgacggt gccaacgctt
    22021 ggcaaaaatt ccgcaacatc actttcccaa tgattttggc tgttgcggca cctactttga
    22081 ttagccaata caccttcaac tttaacaact tctctatcat gtacctcttc aatggtggag
    22141 gacctggtag tgtcggaggt ggagctggtt caaccgatat cttgatctca tggatctacc
    22201 gtttgacaac aggtacatct cctcaatact caatggcggc agctgttacc ttgattatct
    22261 ctatcattgt catctcaatc tctatgatcg cattcaagaa actacacgca tttgatatgg
    22321 aggacgtcta agatgaataa ctcaattaaa ctcaaacgta gactgactca aagccttact
    22381 tacctttacc tgattggtct atcaattgta attatctatc cactgttgat taccatcatg
    22441 tcagccttta aagcaggtaa cgtctcagcc tttaaactag atactaatat cgacctcaat
    22501 tttgataact ttaaaggcct cttcactgaa accttgtacg gtacttggta cctcaacact
    22561 ttgattatcg ccttaattac catggctgtt caaacaagta tcatcgtact tgctggttat
    22621 gcttacagcc gttacaactt cttggctcgt aaacaaagtt tggtcttctt cttgatcatc
    22681 caaatggtgc caactatggc cgctttgaca gccttcttcg ttatggcgct tatgttgaac
    22741 gcccttaacc acaactggtt cctcatcttc ctctacgttg gtggtggtat cccgatgaat
    22801 gcttggctca tgaaaggcta cttcgataca gtgccaatgt ctttagacga atctgcaaaa
    22861 ctagacggtg caggacactt ccgccgcttc tggcaaattg ttctaccact tgttcgccca
    22921 atggttgccg tacaagctct ctgggccttc atgggacctt tcggggacta catcctctct
    22981 agtttcttgc ttcgtgagaa agaatacttt actgttgccg taggtctcca aaccttcgtt
    23041 aacaatgcga aaaacttgaa gattgcctac ttctcagcag gtgctatcct catcgccctt
    23101 ccaatctgta ttctcttctt cttcctacaa aagaactttg tttcaggact tacaagtggt
    23161 ggcgacaagg gataatttat ccccgccacc ctttttcatt ttatactctt cgaaaatctc
    23221 ttcaagccac gtcagcttta tctccaacct caaagttgtg ctttgagcaa cctgcagcta
    23281 gcttcctggt ttgcactttg attttcattg actattagcg attgtcactg taaataatat
    23341 ccttgtagca agcaatttac cccctagact tgaaataaag cgcatttctc tatataataa
    23401 tactcatata gaaaacacct tttagaaaga tacctatgct tccatatcca ttttcctatt
    23461 tttcaagtat ttgggggttt cgtaagcccc tgtccaaacg tttcgagctc aactggtttc
    23521 aacttctctt taccagtatc ttccttatca gcttgtctat ggtacccatt gctatccaaa
    23581 acagctccca ggagacctat ccgctagaaa cttttatcga taatgtctat gaacctctga
    23641 caaatgaggt tgtccaggat ctctctgaac atgctacaat tgtcgatggc acattaactt
    23701 atactggaac agctagtcaa gccccttctg ttgtgattgg tccaggtcaa atcaaggaat
    23761 tacctaagga cttgcaactg catttcgata caaatgagct agtcatcagc aaggaaagca
    23821 aggagctgac ccgcatctct taccgagcca ttcagactga gagtttcaaa agcaaagaca
    23881 gcttgaccca agcaatttct aaagactggt accaacaaaa tcgtgtctat atcagcctct
    23941 tcctagttct cggtgcgagc ttcctctttg gtttgaattt ctttatcgtc tctctaggag
    24001 ctagtcttct cctttatatc actaagaaat cacgcctctt ttcatttaga acctttaaag
    24061 agtgctatca ctttatcttg aactgtttag gattgccgac tctgattaca cttattttgg
    24121 gattatttgg ccaaaatatg acaaccctga ttactgtaca aaatattctt tttgttctgt
    24181 atctggtcac tatcttttat aaaacacatt tccgtgatcc aaattaccat aaataggaga
    24241 tttttatgcc cgttacgatt aaagacgtgg ccaaggctgc tggtgtttcg ccttcaaccg
    24301 taacccgtgt tattcaaaat aaatcaacca ttagcgacga aacaaaaaaa cgcgttcgca
    24361 aagctatgaa ggaactcaac taccacccaa acctcaacgc tcgtagcttg gtaagcagct
    24421 atactcaggt tatcggatta gttcttcctg atgactcaga cgccttctac cagaatcctt
    24481 tctttccatc ggttctacgt ggcatctctc aagtcgcatc tgaaaaccac tatgccattc
    24541 agatagcaac aggaaaagat gagaaggagc gtctcaacgc tatttcacaa atggtctacg
    24601 gcaagcgtgt agatgggcta atctttctct atgcccaaga agaagaccct ctcgtaaaac
    24661 tcgtcgcaga agaacagttc cccttcctta tcctaggtaa atctctatct cctttcatcc
    24721 cacttgtcga caacggcaat gttcaagctg gttttgatgc gactgaatat ttcatcaaaa
    24781 aaggctgcaa acgcattgcc tttatcggag gaagtaaaaa gctcttcgtg accaaagacc
    24841 gtttaacagg ctatgaacag gcgcttaaac attacaaact taccactgac aacaatcgca
    24901 tctactttgc cgacgagttt ctggaagaaa agggctataa atttagcaag cgattattca
    24961 agcacgatcc acaaattgat gctatcatca caaccgatag cctcctagct gaaggtgttt
    25021 gtaactatat tgccaaacac cagctggatg tccctgttct cagctttgac tcggttaatc
    25081 ccaagctcaa cttggcagcc tatgtcgata tcaatagttt agagcttggt cgtgtttccc
    25141 ttgaaactat tctccagatt attaatgata ataaaaacaa taaacaaatt tgttaccgtc
    25201 aattgatcgc ccacaaaatt atcgaaaaat aagagactgg gcaaaaagtc gttaaaagca
    25261 aaaacgcata gtatcaggta ttgaaaaaac ttgatactat gcgttttaat gtgggaagat
    25321 ttacttcctt ttctactgaa attgagtctt tttccaagat ctttttatac tcaatgaaaa
    25381 tcaaagtgca aactaggaag ctagccgcag gttgctcaaa acactgtttt gaggttgtag
    25441 atgaaactga cgaagtcagt aacataccta cggcaaggcg acgctgacgt ggtttgaaga
    25501 gattttcgaa gagtattaat cactaattat ctatctcaac aaatcttcct agaatatgaa
    25561 cattttccga gacagagaca aaggagcttg gatccacttg tgtcataatc tgtttaaatt
    25621 cattaaactc tgcacgtgta atgacagtga ttaaaactgc ctttctctcg tgattatagg
    25681 ttccttctgc atcgtggatc atggttgctc cgcggtgcaa ttttttatgg attttttcaa
    25741 ttaccttctc tggatgattt gtcacaatca tggcctgcat acgcttttgc ttagtaaaga
    25801 ctgcgtctgt cacacggcta gagacaaaga tggtaatcat agaataaaga gcgtatttcc
    25861 aaccaaaggt caaacctgct atcagcatga tagttccatt taccaagaaa gaaatactac
    25921 cgacattctt acccgttttc ttacgaatag tcaggctaac gatatccgtc ccaccactgg
    25981 agatattgtt tcgaagagca aaaccaatcc ccaaacccat aacaacaccc ccaaaaaggg
    26041 aattgataat gggatcctcc gtcaaggttg ccacagggac aaactggata aagaaggaac
    26101 tcatagatac cgtgataaag gtaaagacgg tgaacttatg gccaatctga taccaagcta
    26161 agaccatcaa agggaagtta atggcgtaga agcttagcga aatcggaata tgaaaaccaa
    26221 accagtgatt actcaaggca gagataatct gtgccagacc tgttgcacca ctcgaataca
    26281 catgccctgg ttggaaaaag aaattaactg ctactgctga taaaaaacca tagaccagag
    26341 aggccgaaat cttctcatca tacttttctc gagagatact ttgtaagaca cgtaaaattt
    26401 ttatctgata agcaaagcgg cgcagataat agcgccaccg cttaattcgt tttgtttgtt
    26461 tcatcttctt ctacttgtaa gctgagttcc tctagttgtt tgagagcgac tgttgatgga
    26521 gcttgtgtca ttgggtcagt tgccttgttg ttcttaggaa aggcaatgac ttcacggata
    26581 ttttcttctc cagcaagcaa catgacaaaa cggtcaagcc cgatagccaa accaccgtgt
    26641 ggtgggaaac catagtccat ggcttcaaga aggaaaccaa actggtcatt ggcttcttca
    26701 gctgagaaac caagagcctt gaacatgcgt tcttgaaggt ctttttggtt gatacgaagg
    26761 ctaccaccac caagctcata accgttcaag acgatatcgt aagcaatggc acgaacctta
    26821 gccaaatcac cttctaattc gtgagcagtc tcttcctgtg gaagtgtgaa tggatggtgg
    26881 gcgctcatgt agcggccttc ttcttcagac cattcaaaca tcggccagtc aaccacccaa
    26941 aggaagttga acttatcatt atcaatcaag ccaagctctt tagcaatacg tccacgaagg
    27001 gcacccagtg ttgcattagc cacttcaagc gtatccgcca caaagagaac caagtcctta
    27061 tcttcaagag caagcgctgt tgtcaattct tcttggatac cagtcaagaa cttggcaact
    27121 ggtccgttta attctccatc aaccaccttg acccaagcaa gacctttggc accatactgt
    27181 ttggctactt ccgtcatctt gtcgatgtct ttacgtgaat agttgtccgc agctcctttg
    27241 accacaatcg cttttacagc aagtgcttct gaaaagactt taaagtctac acctttgacc
    27301 acttctgtca agtcctgaag caacatgtca aaacgagtat ctggcttgtc agaaccgtaa
    27361 agagccatag catcatcgta tttcatacga gggaacggta gcgttacttc gatgcctttt
    27421 gtttccttca tcacgcgcgc gatcaagcct tctgtaatat cttggatttc ttgctcagta
    27481 aggaaggacg tttccaagtc gacctgagta aattcaggct ggcggtctcc acgcaagtcc
    27541 tcgtcacgga aacatttaac gatttggtag taacggtcaa aaccagcatt catcaagagc
    27601 tgtttcgtga tttgtggact ttgaggaaga gcgtaaaaat gccccttatt aacacgagac
    27661 ggcactaaat aatcacgcgc cccttcaggc gttgacttag aaaggaatgg tgtctccacg
    27721 tcgataaact ccaactcatc caaatagttg cggatagagt gggtcacctt ggcacgaagt
    27781 ttaagatttt ccaacatttc tggacgacga aggtcaaggt aacggtaacg caaacgtgta
    27841 tcgtcatttg cctcaatgcc atccttaatc tcaaatggtg ttgtcttagc tgtgttaagc
    27901 acaataagag ctgtcacgtt taactcaacc gcaccagttg gcaacttatc attggcttgc
    27961 tcacgcgcag cgacctgacc agtcacctca ataacaaatt cgctacgaag gctttcagct
    28021 gttgccataa cctctgcaga tactttttca gggttgataa ccaactgcat gattccttca
    28081 cggtcacgaa gatcgataaa gatcaaacca ccaaggtcac gacgacggcc aacccatcct
    28141 ttcaaggtta tttcttgtcc gatgtgttcc tcacgaacac gaccagcata catactacgt
    28201 ttcattattt ctctcctctt ttattctgtt actattttac cataaaagcg caggctcttc
    28261 atgaaaatca tcagaaaagt ttgccagtct ttaaaagtca ggtgaaagcc ctaaaaatta
    28321 gcgctaatgc tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac cgtagtacgg
    28381 ttactgactt cgtcagtttc atccacaacc tcaaaacagt gttttgagca acctgcggct
    28441 agcttcctag tttgctcttt gattttcatt gagtataata caaaaatccg atgaacttca
    28501 ccggactctt ttattttgaa tttttgcctg ctttacgctt ttcagcgatt tcggctgcct
    28561 ttcgaggcaa gacaatttcc gttatgtaag ccgtcccaaa acgcagtaca cctgcaatag
    28621 gagcaaagac aactgctaga tagttataga agaaatcgcc tttgaaggca taagctagcg
    28681 ctccaatgat gaaaaataga acgactgcct gaatcactgc taataaaatt actcgtttca
    28741 tgtgacctcc tgactctatt atagcatgag aatcatcaaa aagccgacta aattattcaa
    28801 agcgtgaaga gaaatactgt agaccagacc ttttctgcta acgtaagcca aacccaaact
    28861 aaaaccaagg ctaaaataga caaaaaattg ttgcacatca cctggaaaat gaatcaaggc
    28921 aaatagaaga ctagatacca gaagaaaaat cagggttcgt ttactattgt cctgcttagg
    28981 aaagagatag cgtgctaaca tccctctaaa aacaatctct tccgtcaaag gagcaaaaat
    29041 aaccacagca aagaatgaga aaagtggttg agaaaaggtc aagtctgtcg ctatttgttg
    29101 atttactgaa ggatcatctg gcaagaagaa ttgaacgacc agagataaga accaaaccaa
    29161 gacaggaagc caaataaatc gattaaagcc gctcttctca atatgaacag gagccttctg
    29221 ataccatttg taaatgccgt acacatatac tccagccaag gccacataga gtagagtaac
    29281 agcatagggt gaagcgccta aagcaagcga cgcagtcgcg agcccctgaa taaagccata
    29341 gataaataaa aaggatagaa gggctagaag aatccagcca aggtttttaa gtaatttcat
    29401 agataactcc tttatttgaa ataacgtttt accataggta actgcatcac attgatataa
    29461 acatggatgg ctcctacaag caagaaagct agtaactgaa tctctcctgt caagaaagaa
    29521 atgataataa gaaaaatata taaggctggt aagacatatt ggtgtaattg gaataaaatt
    29581 cgaaaactct gttccaaatt agcctgacgc tccccttcat cataagaatt tatatagttc
    29641 aagacatcct ttggtgtagc gaaaaattcc aaatcaaact gacgaacaat cgcaatggtt
    29701 ttaaaaagag atttttgagc gactaagaat accacaaaga gtaagaaaga aaggaaaaat
    29761 gtttgagggt ttgtatgcaa tataatcacc tcacttaatg aaataaaaat agccaatgga
    29821 atcgctacac ctgtaatatt aaaagcaatg gttccaaact caagattccg atacatttgc
    29881 acataatagg tttcattcag atcgtcatcc atttcctctt gatacaagga atgaaatttt
    29941 ctgcttttct ttaagaaatt gaaagtcaaa agcatactaa tgaaacctat cagtaaacaa
    30001 atagctgata tccatggcat caaggctttt acatctaaaa taatttcgtg ggattcgaca
    30061 cgtgccttaa acatccctac aaacatgccc aagaaccccc ccaagacaat agacatcaaa
    30121 aataacaatc tacgtttctt tttcatattc attctccttt ttcacttgct agatttttgg
    30181 atttcttttc aatccattca attactggga tgagagcaaa gtagacccaa acaaattggt
    30241 cgctttgata gggattaaac cagcttaggt ccatcccaat cagtagaaat acactgacta
    30301 ataaagctat gaccactaca taataaatca ctttatactt gttcatcact cgtcctcctc
    30361 caaacgaaat accgattcga ctgtttcgtt gaaaatttga gatattttca gggcaatgat
    30421 aatggatggg gtgtactcat cccgttctag taggctaatg gtctgtctgg aaacccctgc
    30481 cagtttggct aggtcggttt gattgagacc atcgcgagct cgaagctctt ttagacgatt
    30541 ttttagttgc acgttacaca cctactctcc gtcaaattca acggtttgga tatcttcaat
    30601 acgttgcaac ttgaattttt cttttcccgt attatctaca cgtcgtagct ttacccattc
    30661 ctcatcaaca tccacaactt cccagttatc tggcccaata tacactcccg ttataattgg
    30721 tttctttcca atcatttctt gcaataatct cgacatctct gcgtttcctt tctcttttcg
    30781 ctcaagcttt ttgattttat tctctagttt cttgattttt ttagaattat tagaataaaa
    30841 gaaaataata aatagtataa atactagtac ccacatcata gctcctttct tcttttctct
    30901 taacttgctt acattgtaac acatcttttt ctttttgaca agtatagttg tcaaaaagtt
    30961 tatgattttt gtcattttgc aaaataaaaa ggtcaggagt aagttcctga ccactttatc
    31021 tatcattaat actcttcgaa aatctcttca aaccacgtca gcttcacctt gccgtaggta
    31081 tggttactga cttcgtcagt tctatccaca acctcaaaac agtattttga gctgacttcg
    31141 tcagttctat ccacaacctc aaaacagtgt tttgagcaac ctgcggctag cttcctagtt
    31201 tgctctttga tttttattga gtataaaatc ctagtttttc aaagatttct gagaagtttt
    31261 ggctgattgt ctcaagtgac acttgcactt cttctcgggt ttggttgttc ttgactgtca
    31321 cttgtctgct ttcgacttcg ctctctccta gggtgatgag ggtcttagcc gcaaagacat
    31381 cggctgactt gaactgagct ttgagcttac ggttgaggta atcacgctct gctttgaaac
    31441 cttgttggcg aagagcttgg actagttcta aggctttgac atttgctcca tcacccaaga
    31501 ctgcgatata gacatctagg gcattttcga tagggagggc cacgccttgt ttttcaagga
    31561 tgagaagcag gcgctctaca ccaagcccaa aaccaaatcc agcagtttca gggcctccaa
    31621 agtaagcaac caaaccatcg tagcgaccac ccgcacagac tgtcaagtca ttgccctcaa
    31681 tctctgtgat aaactcgaaa atggtgtggt tgtagtagtc cagaccacgc accatattgg
    31741 tatcgatgat gtaatctact ccaagatttt ccaacatctg acgcacagca tcaaaatgag
    31801 tttggctttc ttcatcaaga aagtccaaga tagacggcgc attctctact gccaccttgt
    31861 cttctttttc cttagagtcc aagacacgaa gaggattttc ctccaagcga cgttggctat
    31921 ccttagacaa ggtctccttg agcggtgtca aatagtcaat caaggcttgg cggtaggctg
    31981 cacggctctc aggatttcca agagtgttga ggtgcaattt gacaccttga ataccgattt
    32041 ccttcaaaaa atgggctgcc ataacgattg tttccacatc ggtagctgga ttgctagagc
    32101 caaaacactc aacaccaatc tggtggaatt ggcgcaagcg ccctgcctgt ggacgctcat
    32161 aacggaacat aggtcccata tagtagaact tgcttggctt ttgcacttct ggggcgaaga
    32221 gtttattttc cacataggaa cggacaacgg gcgcagttcc ttctggacgg agggtaatat
    32281 gacggtcacc cttgtcataa aaatcgtaca tttccttggt tacgatatct gttgtatctc
    32341 cgacagagcg gctgataacc tcgtaatgct cgaaaatagg cgtacgcact tctgcgtagt
    32401 tgtagcgctt gaaaatttca cgggcaaagc cctcaacgta ctgccatttg gcagattcag
    32461 caggtaaaat atcctgcgtt ccttttggtt tttgtaattt catagggaat cctctttaaa
    32521 cttaatagtc ttattttacc acaaataaag ggattaaaac agtgagaaaa aaattaggat
    32581 ttagatatca tttttgagat taagaattgt taaaaaaata gctagcaagg aaaaaccaac
    32641 aaatagcatc caagtcaact gcatgttcca tacggctact agtgaaaaac aagctgttcc
    32701 cacaggtatg gataaggtaa acaatagacc gaaaaaatta ctagtacgaa ctagaacctc
    32761 tggagctaga tttttcatga gcatggcact aatctttggt tgaactttac cagacacata
    32821 cagagtaaag aagagaaata gcaaaccaag cacgacttga ttgaataaat tagccaaacc
    32881 aactagacta agtcctacgg tctcctacat catcaatcta ggcaaggact gcttcccaaa
    32941 ataatcattg cccgtaaggc tactgatgat aactgctact aaaacacaga attgattgat
    33001 aaatagtgcc tctgtataag aaaaattcaa gagagaatgg ctcaaaaaga agatattata
    33061 aattccaccc aaagcgccac ccaaggaatt aataagcaag acagcaaaga gcataaaacc
    33121 aaagtttttc tgtccacttt taagaaaaac gagacgtaaa tttcggtaaa ttgttaggaa
    33181 ctggtctttg atagaaagct tctcattttt taagttttca ccatcagcag atgacattga
    33241 caggctcaat ttgctttttc ctaaaaagag gatagtggct gatactagga aaaagcaggc
    33301 attgattccc gcaacgagag aaaaattgtt gaccgataga gctaagagcc agactccgaa
    33361 agcttgacca ccaatagctg aaatataggt gatgaactgt gaaaaagaat aagcctccat
    33421 cagatcatct tcagctactt tttccttaat aagaggcatg cgcaagccac ctgcaaaatc
    33481 actgatgaca tcactaatga cattgatcaa acacaggcta gaaaaggcaa agagactagc
    33541 ttgctgaaca actagggctg ccagaaaaaa taaaaccgcc tgaaacaaac cgctatagac
    33601 catccatttg accttgtccc tcgtataatc tgcccgaatc cctacaaaaa ctgtaaagag
    33661 agtcggaaga atcatgacaa tattcgccat agcaaccgca aaagaggctt gtgacaaggt
    33721 cgatgcatag acgataaaga ccaggttgaa aatcgaagca ccaaaagcat tgaagaagcg
    33781 tgataaagtc aaaattctat aagctggatt tctaaacaat agtttcatag ataatctccc
    33841 ttcttgttct aagttctaca tcaagaatag ctttagtata gcacttatga atttgcgaaa
    33901 cgattctttt gaatatatgc aacaaacaaa atgagcaaaa aaacgataga acttttgtaa
    33961 tgacctgaga gagggcaaca gttctatcgc ttcaaatttt ttcttggttt gcagatactc
    34021 aacattcggt cgtatttcta tagtattcgg cagatttatt acagccaagc atctcaaaaa
    34081 tacggacagc atcctccatc tttttctgac cttccttgac tctaccttgc ttgctatcaa
    34141 ggagaccttc tgcccacaga taaacaattc ggaaataggt ctcatttccc ttgtagaaat
    34201 gctcttcgat aacacgttta aaataatagg cattggtaaa ttcttcacac tcaatactag
    34261 ctaaaaagcc attcaatagt atagtatgaa aaaggtttcg attgccagac atttccatta
    34321 gaaaatcgga tttacgtacc atttctcgta catatctagt aaaaagagaa acagataaaa
    34381 atggagaact gactgaaaat aaattgagtt catagattcc ccagatctcg gtagaaaaca
    34441 aataatcatg aaggactttt ccttcctctg ctgttaagtc taccctttca tctatgctct
    34501 tcatataaga cttgataata atggcattta gaatatgttt ctgtttgttg tgagaatggg
    34561 catgcttttg atactccctg cgatataagt cctcaagagg tgctatattc tttggttcca
    34621 agacatctgt aatttctttt ctcaactcag aatctgtatc atactggaaa cctctcgcca
    34681 gaaagaggat ctcctccaca ctggcagata tattttccag agcaaataga aacttttcca
    34741 ccgaaagctc actctgacct gtttcaaaac gggacaacat agacggcgaa aattgtcctc
    34801 cggttgcttg tctcagtgag atatttcttg attctcgtaa ttgtctaaag acttttccaa
    34861 tctgctccat agacttcccc ttgattccgt attttcttca ttttatcata tttttcagaa
    34921 aattcatcaa aaacttgcca aattgtcaga attatgagaa aatagaggat atttatcacg
    34981 tggagggact gctatgagag acgatatcaa aatcaatgac cgtgctttgg ccttgcaaga
    35041 ccaaattatc gaaaaactag agaaagtttt tgatacagat gtggaattgg atgtttacaa
    35101 tctaggtctg atttatgaaa tcaatctgga tgaaacgggg ctctgcaaga ttgtcatgac
    35161 cttcaccgat actgcctgtg attgcgccga aagcctgcct attgaaattg tggcaggtct
    35221 gaaacaaatc gagggtatca aagatatcaa ggttgaagtt acctggtcgc ctgcttggaa
    35281 aatcacacga atcagtcgct atggccgtat tgcccttgga ctaccacctc gttaagcagg
    35341 ccaatcactt ttaaagatga aaaaagcaag ccgaaaatgg cttgcttttt gatactcaat
    35401 gaaaatcaaa gggcaaacta gaaaactagc cgcaggttgc tcaaaacact gttttgaagt
    35461 tgtggataga actgacgaag tcagctcaaa acactgtttt gaagttatgg atagaactga
    35521 cgaagtcagc tcaaaacact gttttgaggt tgtagataga actgacgaag tcagtaacca
    35581 tacctacggc aaggcgacgt tgacgtgatt tgaagagatt ttcgagtatg agtttatttt
    35641 ttacctgact tgtccatatt ccagaagtct gtcacggctc cgcgtgaagc agatgatacg
    35701 atgtgggcat atttaccgag gacaccacgg ctgtaaagtg gtggcaaggt tgtttctgcc
    35761 ttgcgttttt caagttcttc ttcggatacg gccatggaaa tttctttggt atcttggtca
    35821 accgtaacga tatcgccggt acggagatag gcaattggtc caccatcctg agcttcagga
    35881 gcgatatgtc caacaaccag accataagta ccaccagaga aacgtccgtc cgtcaagagg
    35941 gccaccttat ctccctgacc tttaccaaca atcattgatg aaagtgacag catctcaggc
    36001 ataccaggac cacctttagg tccaacaaaa cgaacaacga ctacatcgcc atcaacgatt
    36061 tcatctgtca gaacggcctg aatcgcatct tcttctgagt caaagacctt agctggccca
    36121 acgtgacgac gcactttaac acctgatacc ttggcaactg caccgtcagg agcaaggttc
    36181 ccgttcaaga tgataagcgg accatccgca cgttttggat tttcaagtgg catgataact
    36241 ttttggcctg gagtcaagtc tgcaaagtca gccaagtttt cagctacagt cttaccagta
    36301 catgtgatgc gatctccgtg aaggaaacca tttgccaaca agtacttcat aaccgcaggg
    36361 acaccaccga cttcgtagag gtcttggaag acatactgac cagatggttt caagtcggcc
    36421 aagtgaggca cacgttcttg aatcgtattg aagtcctcaa gtgacaagtc aacatttgcg
    36481 gcatgggcaa tggcgagcaa gtgaagagtg gcgtttgtag aaccaccgag agccatcgtt
    36541 acagtaatag catcttcaaa ggcttcacga gtcaagatat ctgatggttt gagaccaagt
    36601 tccaacatct taacaacagc acgtcctgct gcttcgatat cttctttctt atcagctgat
    36661 tcagctgggt gagaggatga ccctggcaaa ctcatcccta gaacttcgat agcagttgcc
    36721 atggtattag cagtatacat accaccacaa ccaccagggc cagggcaggc attacattca
    36781 agacgtttca cgtcctcagc tgtcatatca ccgtggttcc attttccgat accttcaaag
    36841 acagaaacca agtcgatatc tttaccatca agatttcccg gtgcaatagt tccaccatag
    36901 gcgaaaatag ctgggatatc catattagca atagcaatca tagatccagg catgttcttg
    36961 tcacagccac cgatagcgac gaaggcatcc acgttgtgac cactcatagc cgcctcgatg
    37021 gagtccgcga tgatgtcacg agatgttaga gagaaacgca taccaggcgt tcccatagcg
    37081 atcccgtccg ctacggtaat ggttccaaac tgtacaggcc aagcgcctgc agatttgaca
    37141 ccttctttag ccagtttccc gaaatcatgc aagtgaatgt tacatggtgt attttccgcc
    37201 caagtcgaaa tcactcccac aatcgatgtt tcaaagtcct tatctgtcat accagtcgca
    37261 cgaagcatag cacggttagg tgatttaacc atgctgtcat agatgctact gcggtgacgt
    37321 ttatctaatt cagtcatctt atccctccca tttcagtttt tactattata gcacaattta
    37381 aaggcaatga acagaataaa attcttgaat tttcagaaaa ttctatacac atgtgaaata
    37441 tttaaaatta aaaacaacaa agcggattag tgcactttct gatgaccaga atatgctttt
    37501 taatccgctt tctttaaata acgtaatgta atttttacag aaattctttc agataagtgt
    37561 atttaacatc tatcttgcat tataaatttc tagaaccttc tcttttatat tcgattcact
    37621 caaaccatac tcattaagaa gatagtccat tttccctact tgaccgaatc tttcttgaac
    37681 acccatccga tgaatttttg ttattccatc atcagagaat aattcacata aagcactgcc
    37741 aattccacct atctgattgt ggttttctac agtaaatata gtttttccac ttaacattgt
    37801 ttttatctgt tctggtatcg gtttgattct aaataaatct atcacaccta ctgaataacc
    37861 taatttagac agttcatctg caactcgaat acttggagca accattatgc cagaagcaac
    37921 gattacaaga tcttcaccat gccttaactc aatgtagcct ttagaaaaat cttctccacc
    37981 ttgatacaca ggaactggag cttttctaat tgttcgaata tattttagtc cttttaagtc
    38041 taatgtctgg ttcaatattt cacgaaattg gatatcatca gttgcttcaa aaatgatcga
    38101 tttaggaatt aaacgtaaca atccaatttc ttcaaatggc atatgtgtcc caccattcat
    38161 ttctgcagtt actcctgcat ctgatccaat cacagtggca tccaattgtg cgtatccaag
    38221 agaaataaat aattgatcaa atactcttcg tgaagcaaaa ggaccaaatg tatgaagata
    38281 aggtctaaac ccctgaatag acaagcctgc tgcaaggccg accatttctg cttccataat
    38341 cccaacattc acataacggt ctccgaagtc cttttcaaga ttatgagtag ccatcgaact
    38401 tgacaaatcg gcttctaaga ctactatatc agaataactt tgattagcct ctaaaaggaa
    38461 gtctctatat acatgccgta attctttcgt acttctcatc attctgtttc ctccaattcc
    38521 tgacttaatc tttctacaac tgaagttaac atttgtttct cctctacagt agggcgaaga
    38581 tgatgattgg atttcatttc ttccagctct tgaacccctt gacctttaat agtatctaat
    38641 acaatgcact taggtgatga attatttgac tgttttaatt ggacaatccc ttcataaatt
    38701 tctctaatat ctgaaccctt gaccctaatg gattcaaatc caaatgctga aaatttttct
    38761 acgaaatcac ctggattaca aatatccttt gtaaaaccat ctaattgttt tttgttatca
    38821 tcaacaaata caattaagtt ggataactgt tgatgagaag caaactgtat agcctcccaa
    38881 cattgtcctt catttaactc accatctcca acaatagcat aagtataaaa gggactcttt
    38941 cttattctct gaccatatgc aagtccagtt gcaacactaa ttccttgtcc taaagagccc
    39001 gttgtcatat ctatgcctgg cgttagattt ctatcaggat gagacggtaa tttggttcca
    39061 tttgtattta aagaatataa gaattctttg tcaaagaaac cattcaaata gagtgtactg
    39121 tatagagctg gtcctccatg accttttgat aatatgaaat aatctctatc tcgtgctgca
    39181 aatatttctg gagtcattgg cattatttca ccataaagca ctgctaaaac ttctacgata
    39241 gacagacttc ctccgtaatg tccgaatcca agatgattca atgttctaag agtatttaat
    39301 cggatgttag tcgcaaattt tcttaactca tcttctctat ttttacttaa aatcatccct
    39361 tattcctcct ttgcagatgg ctttttaata aaggatactc caaacataac tgctaaaata
    39421 agaacaagac caatcacaat gcctgcttgt gagccaaatt gatttaacat tcctaaaata
    39481 attcctgata gaccaaaatc tgcatctgag aaagttgatc cttggaaacc gagtcctccc
    39541 aaaactggca ttaaaaagac tgggagaaaa ctgattaaaa taccttgtaa aaatgctcca
    39601 atagtggctc cacgaacacc accagatgca ttcccaataa cacctgcagt cgctccacag
    39661 aagaaatgag gcacaacgcc tggtaagata acaaccgttc ctgaagcaat cataattgcc
    39721 atacttacta aaccaccaat aaaactagag ataaatccaa ttagaactgc attaggtgca
    39781 taagtataaa caatcggaca atccaaagca ggttttgaat taggtacaag acgctctgaa
    39841 atacctttaa aggctggaac aatttcgccc aaaataaggc gaacacctgc taaaataaca
    39901 aatacccctg ctgcaaattg acctgctaat tgtaaagcat aaactagacc acttgtacca
    39961 ctactgattt ctttttctat atattctgac cctgcaaaga tagctacaat aatgtaaata
    40021 actgccatgg ataaagtaat actaacagta ctatcacgta aaaaagctaa actctttgga
    40081 aatttaatgt cctctgttga ttttgatttg tcaccgataa ggctaccagt aaaaccactc
    40141 aaccaatatc ccaaagaact gaaatgacct aaagccacct tgtcatttcc agttaattga
    40201 accatatatt tttgaacaaa tgctggggaa atactcataa taataccgag tgctaatcct
    40261 cctagtaaga taagaggcaa gctagtaaag ccagcaactg ataaaatgac cgcaatcata
    40321 catgccatat atagagtgtg gtgccctgtt aaaaaaatat atttaaatcg agtaaaacga
    40381 gcgattaaga tattgaacac catgcctgca aacataatca gtgcagtagc tgagccatat
    40441 gttgttaaag ctacagctac aattgcttca ttattcggca caacgccaga taaatgaaaa
    40501 gcatgctcaa acatggtacc aaatggattt aaagaatttt gtacaattcc tgcaccacca
    40561 gatacaacta agaaaccaac aaaggtctta attccacctt taataatatc aggtaatttc
    40621 ttcttctgaa gaactaatcc taaaattgca attaaagcta ctaaaatagc tggtgtacta
    40681 acaatatcca atatgaactt catcatgacg ctagcctcct atataagtcc tttttcttca
    40741 caaagtttag taattaattc tcgtagttca tccatatcaa taatactatt taagatacga
    40801 acatctccaa gatgactagc tgaatcagct agatcacgac caacaatcca aatatcagct
    40861 gcatttggat ctgctccacc taaatcataa tgttcaactt ctacatccga aacattcaaa
    40921 tcactcaata cagattcaat attcatctgt accataaaac ttgaacctaa tcctgaacca
    40981 caagctgtac caatttttaa cattatctaa tcctcctgtt taattatcat tttaatgtca
    41041 tcatagtttt ttgatgaaat taaagtttga acatgatttt tatctcttaa aattgttgtt
    41101 aaatgtgaca aagcctttaa atgactctca ttatcaatgg ctgcaataca aatcaacaat
    41161 cttacctctt gttctggatt atccaataaa taaatcggtt cttccaaaac taacattgac
    41221 attcctattt cattcacacc ttcatctggc cgagcgtgag gaattgctac tcccttccct
    41281 aaattaataa aaggcccaaa ctcttctact ttttgaatca ttgcctcagg gtagttctca
    41341 gttatcttat cttgatccaa aagcggttta gctgctaaac gaatcgcctc cttccatcct
    41401 aatttttgcg aactaacctg ataggtttct ttggtaatga gttgttctag cactggtaca
    41461 atttcctttc tatcattttt ttggtaaaga taattcttta acgccaatct taattccaat
    41521 tcttgtgtaa taattccata tcttttgaca atattcagga tttgttcaat ctcaaaatcc
    41581 ccatactcta aattcggaaa atcttttaac actagttcta ctagttgtat tgcttgctct
    41641 tcagtcatca taaccgaaac tagataattt ggcttttctg tctccacctt tatggtagaa
    41701 aaaaccatat catagtcact actagctttc acctgtaaat catcaatctt tgaggttcct
    41761 ataaactcaa tttgaggaaa taatgctaat agattctctt ttaacatcaa tgaagaacta
    41821 acaccattag gacaaatgat tgctgcttta tagcattttt gaggcaaagt atctgctttc
    41881 tttaaataac ctccgaaatg gataacaaaa tatgctgttt cactatcagg tatgggattg
    41941 tcaatagcgt ccatcaaggg catcaaagaa tctttgacta attcaaataa atcaggataa
    42001 tgttctttaa catgcaatac atattcattt gaactaggta ggccgaactt taatctatag
    42061 taagccggta taaggtggcg gcgaagattt tctctcaatc cttccctttg tttaaaatgt
    42121 aacaaagaaa tatcttccat tctacttata atagcctctg ttaattgatt aaagtaaacc
    42181 ggagcaacat ctacttcacc ttcaaagcaa cttgataata aaacggtgat atagcgataa
    42241 tcatcctcag aaaacaccgt atctataatt cccaaatcaa ccactgtatc caataaaata
    42301 gtggttatat cttgaataac aggagatact aatgtctctg aaagacatac tctttcaaca
    42361 tccctttgat acctacacag aatgaatact aaaccgaaaa ggcaaacttt taattgatta
    42421 acaataggta ctagctgtag cttctcataa taatctttaa ctacctgatt tatcaaatca
    42481 taagttaatg aataccccca actggataaa acataatcca aaccccaaat ccctatggag
    42541 gattccagca actcactaac catttgaaaa gctaagcggt gcttattcca ctctgaaccg
    42601 tgtaaagtat aaccttttgc tctactgtac cctagctcca aatcattatc taacataatc
    42661 tttcttaatg attgaatatc agataaggtt gtattcttac ttactttcaa aaagtcttgg
    42721 taatgattat tcgatataaa atctaatcgg caaaaagtgt aaagatagat taaagctaag
    42781 cgagtcgact ttggtaaaac caattcatcc gacttaataa tatctgtcaa agactgcttc
    42841 gtacgatttg ataaactata gcgaccttgt tttttatcca gcactatccc tttattagct
    42901 agataaggca ctaaataatc tattccttct ttgacttcct ttataggtaa gctcacctta
    42961 acagataatt catataatga tagctcacaa tgatccatca aagtcatcaa aataactagt
    43021 gctctataat caaacatttc tcttcctttc taactacaat tatagtgtaa aaattataag
    43081 aataaaagag tatttgagca caatataatc tcacctttta aaagaaatta ttgggctgaa
    43141 actttttagt gattattttc aactttctat tgacttttaa aaacaaagtg atatcattta
    43201 gatatcaaat aatgggaggt cattcttatg actgaaaaac taatcaattc aaaaccaaat
    43261 ggtgtattcg cattgattct cattgagttg acaatcgtac ttggtatctt tatatttata
    43321 atgggggttg gttcggaaaa catttttgga attattatcg gacctttact aatcgtaatt
    43381 gcaggtctag ctcatgctgg tttaaaagtt gtcaaacctc aggaagctct ggttctgaca
    43441 ctctttggta attatacagg taccatcaaa gaacctggtt tttactttgt caatcccttc
    43501 agcgtagcag tcaaccctgc aaaccacact cgacttggac aaagtggtga tgttagcaca
    43561 aaatctcctt ttttaggagc taaatcatca aatgacaatg atgtaaatct tgaaattggc
    43621 aagaaacaga tttccctcaa agtcatgacc ttgagcaatt ctcgtcaaaa aatcaatgat
    43681 tgcttaggaa accctgtaga aatcggtatc gcggtaactt ggagagttgt cgataccgct
    43741 aaggcagtct tcaacgttga taactacaaa gaatatcttt cattgcaatg tgatagcgcc
    43801 ctccgtaata ttgtccgtat ctacccttac gatgtgtctc ctaatgtgga tactacgggt
    43861 gacgggcaag cagatgaagg tagtctccgt ggctctagcg aaattgttgc taaccgtatt
    43921 cgtgaggaaa tccaaagtcg tgttgaggat gctggcttgg aaatccttga agcacgtatc
    43981 acttacctag cttatgctcc agaaattgct gccgttatgc ttcaacgcca acaagcatct
    44041 gccattattg atgcacggaa gatgattgta gatggtgctg taggaatggt tgaaatggca
    44101 ctagaacggc tcaatgaagg ggaattggta gaacttgacg aagaacgaaa agctgccatg
    44161 gtttcaaatc tccttgtcgt tctttgtggc aatcatgatg cacaaccaat tgtcaacaca
    44221 ggaagtcttt actaaagatg gctgaagcta aaaaaaagca gatccccctt cgactctcaa
    44281 caaagttata cgctgcactc gcatcatggg cagaagacga ctttcgttca gtcaatgggc
    44341 aaatcgaata tctcctcaca gagtgtgtca agcaacggaa aaaagacgga aaatacgtat
    44401 cagaaaccat tgacgaacca tttgagattg atatttaaca ccttctcctg tctgccgtgt
    44461 cggataggag aattttttca tctttttttg tcaagtaact ttactttaca aaaaaaatgt
    44521 gttatcctag tatggttgat gaaaatcagt agattgaatc gaatataaat acctaaagga
    44581 gaaatcaaaa tggcagtacc tgcacgtcgc acttcaaaag cgaagaaaaa caaacgtcgt
    44641 acacactaca aagtaacagc tccatctgta aactttgacg aaactactgg agattactca
    44701 cgttctcacc gtgtatcact taaaggatac tacaaaggac gtaaaatcac taaagctgca
    44761 tcagctgaat aatagaaggg agataccatg cgcgtaaata ttacacttga acacaaagaa
    44821 tctggtgaac gcttgtacct tacttctaaa aacaaacgta acactccaga ccgccttcaa
    44881 ttgaagaaat actcaccaaa acttcgcaaa cacgttgtgt ttacagaagt gaagtaagca
    44941 ttcaatacga atcaatacag aagaaaaacg cttgatcagc gttttttctt tttgttaatt
    45001 tcactatatt gcaagggaaa tcattcgaat gactaccttt tttgaaataa gaatacggat
    45061 tcggacaatt aaaagcaaga ggaactcaaa tgtaagttgg ggttcctttt ttgtatattt
    45121 ttcaaataac gcctctacac tatttgtagc aaattcacca actacagttg tatcttagtt
    45181 aaaataagtt agaatatgta agtgagtacc agatatacca agacatcgtc gccatctaag
    45241 gtatattcaa aatacaaaag ttgaccaact agatttctga atatccttat atatccattc
    45301 ttaaaattgg tttaaatagc gtagtctttt aaactagttt tgagaatcca aaaaatcttc
    45361 ctacatatgt aagaagattt tttagttcag aatgattaga tttagctaat ggatacctat
    45421 cctacccact caccgttagc attgactcga tagccatcgg gtgtagtcgt gtttactaat
    45481 aaatctcctg aattataggt atagtaccat ttaccagaaa ctgtaaacca accagtagcc
    45541 attgaacctg attc
//
LOCUS       DAVMAH010000010        45002 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVMAH010000010 DAVMAH010000000
VERSION     DAVMAH010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.010"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(58..1068)
                     /locus_tag="VYO94_000500"
     CDS             complement(58..1068)
                     /locus_tag="VYO94_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV1759187.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSSDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILHFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            1217..2386
                     /locus_tag="VYO94_000501"
     CDS             1217..2386
                     /locus_tag="VYO94_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1759188.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEVFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2383..3153
                     /gene="recO"
                     /locus_tag="VYO94_000502"
     CDS             2383..3153
                     /gene="recO"
                     /locus_tag="VYO94_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV1759189.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3150..4142
                     /gene="plsX"
                     /locus_tag="VYO94_000503"
     CDS             3150..4142
                     /gene="plsX"
                     /locus_tag="VYO94_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV1759190.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     PYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEGRDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4148..4381
                     /locus_tag="VYO94_000504"
     CDS             4148..4381
                     /locus_tag="VYO94_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1759191.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            4427..4718
                     /locus_tag="VYO94_000505"
                     /pseudo
     CDS             4427..4718
                     /locus_tag="VYO94_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4920..5150
                     /gene="blpU"
                     /locus_tag="VYO94_000506"
     CDS             4920..5150
                     /gene="blpU"
                     /locus_tag="VYO94_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV1759192.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5865..8018
                     /locus_tag="VYO94_000507"
     CDS             5865..8018
                     /locus_tag="VYO94_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1759193.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMIFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVIGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8031..9380
                     /locus_tag="VYO94_000508"
     CDS             8031..9380
                     /locus_tag="VYO94_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV1759194.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKYVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9550..10257
                     /locus_tag="VYO94_000509"
     CDS             9550..10257
                     /locus_tag="VYO94_000509"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV1759195.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNVAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10268..10402
                     /locus_tag="VYO94_000510"
     CDS             10268..10402
                     /locus_tag="VYO94_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV1759196.1"
                     /translation="MENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQGLK
                     "
     gene            10459..14184
                     /locus_tag="VYO94_000511"
     CDS             10459..14184
                     /locus_tag="VYO94_000511"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV1759197.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELKAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVVSDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14277..15719
                     /locus_tag="VYO94_000512"
     CDS             14277..15719
                     /locus_tag="VYO94_000512"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV1759198.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKYEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15756..16778
                     /locus_tag="VYO94_000513"
     CDS             15756..16778
                     /locus_tag="VYO94_000513"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV1759199.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16775..17320
                     /gene="purN"
                     /locus_tag="VYO94_000514"
     CDS             16775..17320
                     /gene="purN"
                     /locus_tag="VYO94_000514"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV1759200.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYKLYPEVVKALFTD"
     gene            17404..17913
                     /locus_tag="VYO94_000515"
     CDS             17404..17913
                     /locus_tag="VYO94_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1759201.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17938..19485
                     /gene="purH"
                     /locus_tag="VYO94_000516"
     CDS             17938..19485
                     /gene="purH"
                     /locus_tag="VYO94_000516"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV1759202.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19607..20869
                     /gene="purD"
                     /locus_tag="VYO94_000517"
     CDS             19607..20869
                     /gene="purD"
                     /locus_tag="VYO94_000517"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV1759203.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRTAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDIIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDGKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21243..21731
                     /gene="purE"
                     /locus_tag="VYO94_000518"
     CDS             21243..21731
                     /gene="purE"
                     /locus_tag="VYO94_000518"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV1759204.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            21718..22809
                     /gene="purK"
                     /locus_tag="VYO94_000519"
     CDS             21718..22809
                     /gene="purK"
                     /locus_tag="VYO94_000519"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV1759205.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAKVTVAPYKVVTSSQDLADIDLSKNYVLKIATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPAIKLHVPAVMLNVLGQHVEVAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            22819..23046
                     /locus_tag="VYO94_000520"
     CDS             22819..23046
                     /locus_tag="VYO94_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV1759206.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            23109..24407
                     /gene="purB"
                     /locus_tag="VYO94_000521"
     CDS             23109..24407
                     /gene="purB"
                     /locus_tag="VYO94_000521"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV1759207.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24462..28400)
                     /gene="strH"
                     /locus_tag="VYO94_000522"
     CDS             complement(24462..28400)
                     /gene="strH"
                     /locus_tag="VYO94_000522"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1759208.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMDFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQEEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKSKLEIPSQPAPSTAPA
                     EESKALPQNPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(28716..29432)
                     /locus_tag="VYO94_000523"
     CDS             complement(28716..29432)
                     /locus_tag="VYO94_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1759209.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29779..31566
                     /locus_tag="VYO94_000524"
     CDS             29779..31566
                     /locus_tag="VYO94_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV1759210.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRNPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31563..32039
                     /locus_tag="VYO94_000525"
     CDS             31563..32039
                     /locus_tag="VYO94_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1759211.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32067..32972
                     /locus_tag="VYO94_000526"
     CDS             32067..32972
                     /locus_tag="VYO94_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1759212.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32959..33774
                     /locus_tag="VYO94_000527"
     CDS             32959..33774
                     /locus_tag="VYO94_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1759213.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33781..34185
                     /locus_tag="VYO94_000528"
     CDS             33781..34185
                     /locus_tag="VYO94_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1759214.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYTSRAAESIVKVNDLLAGFDDDEDE"
     gene            34479..35645
                     /locus_tag="VYO94_000529"
     CDS             34479..35645
                     /locus_tag="VYO94_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV1759215.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35761..36798
                     /locus_tag="VYO94_000530"
     CDS             35761..36798
                     /locus_tag="VYO94_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV1759216.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDIKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37005..37859
                     /locus_tag="VYO94_000531"
     CDS             37005..37859
                     /locus_tag="VYO94_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1759217.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     RGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            38009..38266
                     /locus_tag="VYO94_000532"
     CDS             38009..38266
                     /locus_tag="VYO94_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEV1759218.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(38596..38688)
                     /locus_tag="VYO94_000533"
                     /pseudo
     CDS             complement(38596..38688)
                     /locus_tag="VYO94_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(38724..39020)
                     /locus_tag="VYO94_000534"
                     /pseudo
     CDS             complement(38724..39020)
                     /locus_tag="VYO94_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(39010..39171)
                     /locus_tag="VYO94_000535"
     CDS             complement(39010..39171)
                     /locus_tag="VYO94_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV1759219.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTVQNLDGAYSLYKMA
                     NPEGVEYGN"
     gene            39241..40005
                     /locus_tag="VYO94_000536"
     CDS             39241..40005
                     /locus_tag="VYO94_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV1759220.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            40261..40446
                     /locus_tag="VYO94_000537"
     CDS             40261..40446
                     /locus_tag="VYO94_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759221.1"
                     /translation="MLLTSSVLSATSKQCFELTSSVLSTTSKQCFEQPVTSFLIDALI
                     FIAYNQKEKFSPEKHIE"
     gene            40615..41994
                     /locus_tag="VYO94_000538"
     CDS             40615..41994
                     /locus_tag="VYO94_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1759222.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            42008..42673
                     /locus_tag="VYO94_000539"
     CDS             42008..42673
                     /locus_tag="VYO94_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV1759223.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            42983..43522
                     /locus_tag="VYO94_000540"
     CDS             42983..43522
                     /locus_tag="VYO94_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1759224.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLVEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            43589..43999
                     /locus_tag="VYO94_000541"
     CDS             43589..43999
                     /locus_tag="VYO94_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1759225.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            44115..>45002
                     /gene="pavB"
                     /locus_tag="VYO94_000542"
     CDS             44115..>45002
                     /gene="pavB"
                     /locus_tag="VYO94_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1759226.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLV"
BASE COUNT        12522 a         8675 c        10620 g        13185 t
ORIGIN      
        1 aacatatacc tacggcaagg cgacgttgac gtggtttgaa gagattttcg aagagtatta
       61 gaaaatgccg ataagggtct gcataccaag gctggtgagg atgatggcaa tccagcagac
      121 ggctccgaga acaatggatt ttccactgga tttgaccata gcgaccagat tagttttgag
      181 accgatggca ctcatggcca tgataatgag gaatttagag agttgtttga gaggggtaaa
      241 gaaactacta gacacaccga gagaggtcag aagggtggtt aggagcgatg caaggatgaa
      301 gtgaaggata aaaagtggga agactttttt cagttgtaag ccttgcttat ttttttgctc
      361 gcgactttgc cagtaggaga gaaagagagt gatggggatg atagctaggg ttcgcgtgag
      421 tttgacaatg gttgcggatt cgagggtatt ggtctggtag agactgtccc aagcgctagc
      481 tgtggcggtt acagaggaag tatcattgac cgcagttcct gcaaagaggg cgaagccgtc
      541 actggataga tgaagccagg tgccgagggt tggaaagatg agcgcagcca agacattgaa
      601 gaaaaagata acggagatgg cttgggctac ttccttttcc ttagcatgga taacaggcgc
      661 tgtcgctgca atggcagaac ccccacagat agaagaacct actccaatca aggtagccag
      721 ttttgtatcc agggcaaaga agcgctggaa gaggtaggca acaatcaagg ctattgaaat
      781 ggtggaaagg atgacaggga gtgaagattg cccaactgcg aagacttgag agatattgag
      841 accaaaacca agcaagataa cggcatactg gagcaatttc ttggaactaa aggtcaatcc
      901 aacatccagt tgtttataag acgagagaaa gggatgtagg agcatgccca taaaaatcgc
      961 aaaaacgggc gcgccaatca cagggaagaa tcctcctaag taccaagata cgatagaaat
     1021 gagaaggcag accaagatgc ctgctccatt ttttgataga aatgacataa aaacctccaa
     1081 atagaatctg ttaccattat agacctgtaa acaggaaaag taaaatagaa agtggaaagc
     1141 tattctctaa tgtatttttg cggtcggggg gcttttgtag tataatagag atatgttttg
     1201 aaagtaggag gtatctatgg acttaactaa gcgctttaat aaacagttag ataaaattca
     1261 agtttcgttg attcgtcagt ttgaccaggc tatttcggag attcctgggg tcttgcgttt
     1321 gaccttaggg gaacctgatt ttacaacgcc agaccatgtc aaggaggcgg ccaagcgagc
     1381 gattgatcag aaccaatcct actatacagg gatgagtggt ctgctgactc tacgtcaggc
     1441 ggccagtgat tttgttaagg aaaagtacca actggactat gctcctgaaa atgaaatctt
     1501 ggttacaatt ggggcgacag aggctttatc tgcgactttg acggctattt tggaagaggg
     1561 agacaaggta cttttgccag ctcctgctta tccaggctat gaaccgattg ttaacttagt
     1621 tggggcagaa attgttgaga ttgatacgac tgaaaatggt tttgtcttga ctcctgagat
     1681 gttggagaag gccattttgg agcagggtga taagctcaag gcggttattc tcaactatcc
     1741 agccaatccg acaggaatta cctacagtcg agagcagtta gaggccttgg cagctgtttt
     1801 acgcaagtac gaagtttttg ttgtctgtga tgaggtttac tcagaattga cctacacagg
     1861 cgaagcccat gtgtctctag gaacgatgtt gagagaccag gctattatta tcaatggttt
     1921 gtctaaatcg catgccatga caggttggcg tttggggctg attttcgctc ctgcgacctt
     1981 cacagcccag ttaatcaaga gtcaccagta cttggtcact gccgcaaata ccatggcgca
     2041 acatgctgcg gtagaagcct tgacggctgg taaaaacgat gcggagccca tgaagaagga
     2101 atatatccaa cgtcgggact atatcatcga aaaaatgact gctcttggtt ttgagattat
     2161 caaaccagac ggtgccttct atatttttgc taaaattcca gcgggctaca atcaagactc
     2221 ctttgctttt ctgaaggatt ttgctcagaa gaaggccgtt gcctttatcc ctggtgcagc
     2281 ctttggacgt tacggggaag gctacgtccg cctatcttat gcagccagca tggagactat
     2341 caaagaagcc atgaaacgac ttgaggagta catgagagaa gcatgattca gtctatcacg
     2401 agtcaaggct tggtgcttta caatcgcaat tttcgtgagg atgacaagct cgtcaaaatt
     2461 tttacagagc aggttggcaa acgcatgttt tttgtcaaac acgctggtca gtctaagctg
     2521 gcgcctgtta ttcagccctt ggtgctggca cgatttctct tgcgaatcaa tgatgacgga
     2581 ctcagttaca tcgaagacta tcatgaggtc atgacttttc ccaagattaa tagtgacctc
     2641 tttgtcatgg cctatgcgac ctatgtggca gctcttgcag atgctagttt gcaggacaat
     2701 cagcaggatg ctcccttgtt tgcttttttg caaaagactt tggagttgat ggaagcaggc
     2761 ttggattatc aggttttgac caatattttt gaaattcaaa ttttgactcg atttggaatc
     2821 agcctcaatt ttaatgagtg tgtcttctgc catcgggttg gtcaggcttt tgacttttct
     2881 ttcaaatatg gagcctgcct ctgtccagag cattatcatg aggataagag acgttgtcat
     2941 ctcaatccca atatccccta tctgctcaat caatttcaag ctattgattt tgagactttg
     3001 gagaccattt cgctcaagcc tggaatcaag caagagctac gccaatttat ggatcaatta
     3061 tatgaagagt acgttgggat tcacctaaaa tcaaagaaat ttattgattc cctagcagac
     3121 tggggacaat tactaaaaga ggaaaagaaa tgaaaaaaat cgcagtagat gccatggggg
     3181 gcgattacgc acctcaggcc attgttgagg gtgtcaatca agccctatct gacttttcag
     3241 atatcgaggt tcaactttac ggagatgaag ctaaaatcaa gccctatctg acagcgacag
     3301 agcgcgtcag cattatccat acggatgaga agattgattc ggatgatgaa cctacgagag
     3361 ctattaggaa taagaaaaat gccagtatgg tattggcagc caaggctgtc aaagatggtg
     3421 aagcagacgc tgtcctttcg gctgggaata caggtgcctt gttggcagca ggattcttca
     3481 tcgtgggtcg tatcaagaat atcgaccgtc ctggactcat gtctaccttg cctaccgttg
     3541 atggaaaagg ttttgacatg ctagaccttg gtgccaatgc agaaaataca gcccagcacc
     3601 tccatcaata tgcggttcta ggttccttct atgctaaaaa tgtccgtggc attgcgcaac
     3661 cacgcgttgg tttgctcaac aacggaacag agagtagcaa gggcgacccg cttcgtaagg
     3721 aaacttatga attactggcg gctgatgaaa gtttgaactt tatcggaaac gtggaagggc
     3781 gtgatttgat gaatggcgtt gcagatgttg ttgtggcaga tggtttcacg ggaaacgctg
     3841 tgctcaaatc catcgaaggg acagctatgg gaatcatggg cttgctcaag acagctatta
     3901 caggtggtgg tcttcgagcg aaactaggtg ccctccttct caaggacagc ctcagtggtt
     3961 tgaaaaaaca gctcaattat tcagatgttg gtggagcggt cttgtttggt gttaaggcac
     4021 ctgttgtcaa gactcatggc tcaagcgatg ccaaggctgt ttatagtacg attcgtcaga
     4081 tccgtaccat gctagaaaca gacgtggttg cccagactgc gcgtgaattt tcaggagaat
     4141 aaaagagatg acagaaaaag aaatttttga ccgtattgtg accattatcc aagagcgaca
     4201 gggagaggac tttgtcgtga cagaatcctt gagtctgaaa gacgatttgg atgcggattc
     4261 tgttgacttg atggagttta tcttgactct ggaagatgaa tttagtatcg aaatcagcga
     4321 tgaggaaatt gaccaactcc aaagtgtagg agatgtggtt aaaatcattc aaggaaaata
     4381 gcaatcggag ttccaagtca acggaagtag atggttttta gaaatgagaa atatcggaca
     4441 agctggtaaa atcttggctg acagtggtta tcaagggctc atgaagatat atcctcaagc
     4501 acaaacttcc acgtaaatcc agcaaactca agccgctaac agttgaagat aaagcctgta
     4561 atcatgcgct atctaaggag agaagcaagg ttgagaatat ctttgccaaa gtaaaaacgt
     4621 ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt
     4681 tgattgctgg tattatcaat catgaactag gattctagtt ttgcaggaag tctaatagta
     4741 aaaagtgatt agaaaacatc ttttttaaaa atagagatga ttttgaaaca aaaaagctaa
     4801 ttcaagacgt ttcgattcca attcaagatt tggatgaaaa aaattaatag atactgttat
     4861 actaaacttg tcaagtttgt aacaagacaa atattaaaaa taaaaaagag gtattcgtta
     4921 tgaatacaaa aaagatgtca caatttgaaa ttatggatac tgagatgctt gcttgcgttg
     4981 aaggtggcgg atgcaattgg ggagattttg ccaaagcagg tgttggagga ggagcagtac
     5041 gaggtcttca gctaggaatt aaaacaagaa catggcaagg tgcagcaact ggtgctgcgg
     5101 gaggagctat acttggaggt gtggcctatg cagcgacatg ttggtggtaa ttatggattt
     5161 taaaagtttt attattggtt tagtagttgg tatatttggt ccttatatgg atgatttaat
     5221 tagaaaaaaa tttttaaagt cttcggagaa gaaaacagaa aaatctgtta aaaaataatc
     5281 aaaactataa atgatgaatc tgaatcaaaa ttattttgcg catgtaaaga ggagtcttat
     5341 agtaacgagt caaaaaagga gtaactatga atcgtaattt agaacggtgt tatctattct
     5401 gactaggaat agatcatacc agaggtagct tagaaatagc agggacatta gaaattgaag
     5461 taataaatag gatgtcgtaa gtgttactat caatgattta tttgtttcaa gcttgcctag
     5521 ggtgacagta aaaaatcaat ttcctttcaa tagcatattt ttagtgggca ggactcttgt
     5581 tctgcctatt tttttatcca aaaagtgcag ttgggaggga gataggctca tttgggaagg
     5641 aagtccagtt tttgtttagt gattggggta agatagttgt tatcagatga gtttatactc
     5701 ttcgaaaatc aaattcaaac cacgtcaacg tcgccttgcc gtatatatgt gactgacttc
     5761 gtcagtccta tctacaacct caaaacagtg ttttgagcag cctgcggcta gtttcctagt
     5821 ttgctctttg attttcattg agtattaggg aaaaggagat gaatatgaaa tttgggaaac
     5881 gtcactatcg tccgcaagtg gatcagatgg actgcggtgt agcttcatta gccatgattt
     5941 ttggctacta tggtagttat tattttttgg ctcacttgcg agaattggct aagacgacca
     6001 tggatgggac gacggctttg ggcttggtca aggtggcaga ggagattggt tttgagacgc
     6061 gagccattaa ggcggatatg acgctttttg acttgccgga tttgactttt ccttttgttg
     6121 cccatgtgct taaggaaggg aaattgctcc actactatgt ggtgactggg caggataagg
     6181 atagcattca tattgccgat ccagatcccg gggtgaagtt gactaaactg ccacgtgagc
     6241 gttttgagga agaatggaca ggagtgactc tttttatggc acctagtcca gactataagc
     6301 cttataagga acaaaaaaat ggtctgctct cttttatccc tatattagtg aagcagcgtg
     6361 gcttgattgc caatatcgtt ttggcaacac tcttggtaat cgggattaac attgtgggtt
     6421 cttattatct gcagtctatc attgatacct atgtgccaga tcagatgcgt tcgacactag
     6481 ggattatttc tattgggcta gtcatcgtct acatcctcca gcaaatcttg tcttacgctc
     6541 aggagtatct cttgcttgtt ttggggcaac gcttgtcgat tgacgtgatt ttgtcctata
     6601 tcaagcatgt ttttcacctc cctatgtcct tctttgcgac acgcaggaca ggggagatcg
     6661 tgtctcgttt tacagatgct aacagtatca tcgatgcgct ggcttcgacc atcctttcga
     6721 ttttcctaga tgtgtcaacg gttgtcatta tttcccttgt tctattttca caaaatacca
     6781 atctcttttt catgacttta ttggcgcttc ctatctacac agtgattatc tttgccttta
     6841 tgaagccgtt tgaaaagatg aatcgggata ccatggaagc caatgcggtt ctgtcttctt
     6901 ctatcattga ggacatcaac ggtattgaga ctatcaagtc cttgaccagt gaaagtcagc
     6961 gttaccaaaa aattgacaag gaatttgtgg attatctgaa gaaatccttt acctatagtc
     7021 gagcagagag tcagcaaaag gctctgaaaa aggttgccca tctcttgctt aatgtcggca
     7081 ttctctggat gggggctgtt ctggtcatgg atggcaagat gagtttgggg cagttgatta
     7141 cctataatac cttgctggtt tactttacca atcctttgga aaatatcatc aatctgcaaa
     7201 ccaagcttca gacagcgcag gttgccaata accgtctaaa tgaagtgtat ctagtagctt
     7261 ctgagtttga ggagaagaaa acagttgagg atttgagctt gatgaaggga gatatgacct
     7321 tcaagcaggt tcattacaag tatggctatg gtcgagacgt cttgtcggat atcaatttaa
     7381 ccgttcccca agggtctaag gtggcttttg tggggatttc agggtcaggt aagacgactt
     7441 tggccaagat gatggttaat ttttacgacc caagtcaagg ggagattagt ctgggtggtg
     7501 tcaatctcaa tcagattgat aaaaaagccc tgcgccagta catcaactat ctgcctcaac
     7561 agccctatgt ctttaacgga acgattttgg agaatcttct tttgggagcc aaggagggga
     7621 cgacacagga agatatctta cgggcggtcg aattggcaga gattcgagag gatatcgagc
     7681 gcatgccact gaattaccag acagaattga cttcggatgg ggcagggatt tcaggtggtc
     7741 aacgtcagag aatcgctttg gcgcgtgctc tcttgacaga tgcgccggtc ttgattttgg
     7801 atgaggcgac tagcagtttg gatattttga cagagaagcg gattgtcgat aatctcatgg
     7861 ctttggacaa gaccttgatt ttcattgctc accgcttgac tattgctgag cggacagaga
     7921 aggtagttgt cttggatcag ggcaagattg tcgaagaagg aaagcatgct gatttgcttg
     7981 cacagggtgg cttttacgcc catttggtca atagctagaa agaggagagg atgaaaccag
     8041 aatttttaga aagtgcggag ttttataatc gtcgttacca taatttttcc agtagtgtga
     8101 ttgtacccat ggcccttctg cttgtgtttt tacttggctt tgcaactgtt gcagagaagg
     8161 agatgagttt gtccactaga gctactgtcg aacctagtcg tatccttgca aatatccagt
     8221 caactagcaa caatcgtatt cttgtcaatc atttggaaga aaataagctg gttaagaagg
     8281 gggatctttt ggttcaatac caagaagggg cagagggtgt ccaagcggag tcctatgcca
     8341 gtcagttgga catgctaaag gatcaaaaaa agcaattgga gtatctgcaa aagagcctgc
     8401 aagaagggga gaaccacttt ccagaggagg ataagtttgg ctaccaagcc acctttcgcg
     8461 actacatcag tcaagcaggc agtcttaggg ctagtacatc gcaacaaaat gagaccatcg
     8521 cgtcccagaa tgcagcagct agccaaaccc aagccgaaat cggcaacctc atcagtcaaa
     8581 cagaggctaa aattcgcgat taccagacag ctaagtcagc tattgaaaca ggtgcttcct
     8641 tggccggtca gaatctagcc tactctcttt accagtccta caagtctcag ggcgaggaaa
     8701 atccccaaac taaggttcag gcagttgcac aggttgaagc acagatttct cagttagaat
     8761 ctagtcttgc tacttaccgt gtccagtatg caggttcagg tacccagcaa gcctatgcgt
     8821 cagggttaag cagtcaattg gaatccctta aatcccaaca cttggcaaag gttggtcagg
     8881 aattgaccct tctagcccag aaaattttgg aggcagagtc aggtaagaag gtacagggaa
     8941 atcttttaga caaggggaaa gttacggcga gtgaggatgg ggtgcttcat cttaatcctg
     9001 agaccagtga ttctagcatg gttgcagaag gtgccctact agcccaactt tatccatctt
     9061 tggaaagaga agggaaagcc aaactcacag cttatctaag ttcaaaatat gtagcaagaa
     9121 tcaaggtcgg tgattctgtt cgctatacta cgactcatga tgccgggaat caacttttcc
     9181 tagattctac tattacaagt attgatgcga cagctactaa gactgagaaa gggaatttct
     9241 ttaaaatcga ggcggagact aatctaactt cggagcaggc tgaaaaactt aggtacgggg
     9301 tggaaggccg cttgcagatg attacgggca agaaaagtta cctacgttat tatttggatc
     9361 aatttttgaa caaagagtaa tgttcgtgtt tttagagtta aataattttt aaactgtgag
     9421 aaagattctt cttgcagttt tttctttaca atttttgaaa aacatctact atttattcgg
     9481 ttaaattctt gtgttttttg gttttttgtg gtaaaatgtg ctcaagtaat acgaaaggcg
     9541 aactttaaaa tgtcaaaaca attgatctat tcgggaaaag ctaaagatat ctatacaact
     9601 gaggatgaaa atcttattat ttcaacttac aaggaccagg cgactgcttt caacggtgtc
     9661 aagaaggagc agattgcagg taagggagtc ttgaataatc agatctcatc ttttattttt
     9721 gagaaattaa atgtggctgg tgtggcgact cactttgtgg agaaactttc agacacggaa
     9781 caactcaata aaaaggttaa gattattcct ttggaagtcg tgctccgcaa ctatactgct
     9841 ggttcctttt caaaacgttt tggtgtggat gagggaatcg ccttggagac tccgattgtc
     9901 gaattttact acaaaaatga tgatttggat gatccattta tcaatgatga gcatgtgaaa
     9961 ttcctacaga ttgcgggtga ccagcagatt gcctacttga aggaagaaac gcgtcgtatc
    10021 aatgaactat tgaaagtctg gtttgctgag attgggctta aattgattga ctttaagcta
    10081 gagttcggtt ttgacaagga tggcaagatt atcttggcag acgaattttc accagataac
    10141 tgccgcttgt gggacgctga tggcaaccac atggataagg atgttttccg tagaggattg
    10201 ggagaactaa ccgacgttta tgagattgtt tgggaaaagt tgcaggaatt gaaataatct
    10261 gtttgcaatg gaaaaccttc gtctctcaac taaaaggact caggctgaaa aggttcccca
    10321 gaccttttca ctctgtagag aactaggtga actaaccgat gtttacgaaa ttgtctggga
    10381 aaagttgcag ggtttaaaat aacaacctca aggctgtttg ggaatattgc aagagctgaa
    10441 ataaaggaat aagaattgat ggataaacgt atttttgttg aaaaaaaggc tgattttcag
    10501 gtcaagtcag agagtttggt tagagaactc cagcacaact tgggactatc aagcttgaaa
    10561 agtattcgta ttgtgcaagt atatgatgta tttgacttgg ttgaggactt gtttgcacct
    10621 gcagagaagc acattttctc tgagcaggta accgaccatg ttttagatga agtatctgtg
    10681 caggcggatc ttgctaacta tgctttcttt gccattgaaa gtctgccagg gcagtttgac
    10741 cagcgtgcag cttcgtcaca ggaagccttg cttttgttgg gaagttcgag tgacgtgaca
    10801 gtcaacacag cccaacttta cttggtgaat aaagatattg atgcgactga gttgaaagct
    10861 gtcaaaaact acctgctcaa tccagttgat tctcgtttca aggatatcac gacagggatt
    10921 gccaagcagg agttttcaga gtcagacaag accattccaa aattgacttt ctttgaaagc
    10981 tatacagcag aagattttgc tcgctacaag gccgaacaag ggatggccat ggaagtggat
    11041 gatttgctct ttatccaaga ctactttaag tcaatcgggc gcgtgccaac tgagactgaa
    11101 cttaaggttt tggacactta ctggtctgac cactgccgtc atacgacttt tgagacagag
    11161 ttgaaacaca tcgacttttc agcttctaaa tttcaaaagc aattgcagtc aacctatgac
    11221 aagtatattg ccatgcgcga ggaattaggt cggtctgaaa aaccacaaac cttgatggat
    11281 atggcgacta ttttcggtcg ttatgagcgt gctaatggac gattggatga tatggaagtc
    11341 tctgacgaaa tcaatgcctg ctcagttgaa attgaagtgg acgttgatgg tgtcaaggaa
    11401 ccttggctcc tcatgtttaa aaacgaaacc cacaaccatc caacagaaat tgagccattt
    11461 ggtggagcgg ctacctgtat tggtggagct attcgtgatc cgttgtcagg ccgttcctat
    11521 gtttaccaag ccatgcgtat ttcaggtgct ggtgatatta cagcaccgat ttcggaaact
    11581 cgcgctggga aattgccaca acaagtcatt tctaaaacag cagctcatgg ttattcttca
    11641 tatggtaacc agattgggct tgccacaacc tacgttcgtg aatacttcca cccaggcttt
    11701 gtagctaaac gtatggaact tggtgccgtt gttggtgcgg ctcccaaggg caatgttgtc
    11761 cgtgaaaaac ctgaagcagg tgatgtgatc atccttctcg gaggtaaaac aggtcgtgat
    11821 ggtgtcggtg gtgcgacggg ctcttctaag gttcaaacag ttgagtctgt agagactgct
    11881 ggtgctgagg ttcaaaaagg aaatgccatc gaagaacgca agattcagcg cctcttccgt
    11941 aatggcaatg tcactcgtct gatcaagaag tccaatgact ttggggcagg cggtgtctgt
    12001 gtggctatcg gtgaattggc agacggtctt gaaatcgacc tcaacaaggt gcctcttaaa
    12061 taccagggct tgaatggtac agaaattgcc atctctgaat cacaagaacg gatggcggtc
    12121 gtggttcgtc ctgaagatgt ggataccttc gttgccgaat gtaacaaaga aaatattgat
    12181 gctgttgtgg tggcgacagt aactgaaaaa ccaaatcttg tcatgcactg gaatggtgag
    12241 acaatcgttg acttggagcg tcgtttcctt gacaccaatg gtgtgcgcgt ggttgtcgat
    12301 gccaaagttg tggacaagga tgtcaaactc ccagaagagc gtcaaacatc tgctgaaaca
    12361 ctggaatcag atacccttac ggttctatct gacctcaacc atgcaagtca aaaaggatta
    12421 cagactatct ttgactgctc tgttggacgc tcaacggtta atcacccact tggtggtcgt
    12481 taccaactca caccaactga ggcatctgtg cagaaattgc cagttcaaca cggtgtgact
    12541 catactgcgt cggtcattgc tcaaggtttc aacccatatg tagctgaatg gtctccatac
    12601 cacggtgctg cttatgcggt tatcgaagca actgctcgtt tggtggctgc tggtgccaac
    12661 tggtctaagg ctcgtttctc ttaccaagaa tatttcgagc ggatggacaa gcaagcagag
    12721 cgttttggtc agccagtagc cgcccttcta ggctctattg aagcacaaat tcagcttggc
    12781 ttgccatcta tcggtggtaa ggactccatg tctggtacct ttgaagaatt gaccgttccg
    12841 ccaaccttgg ttgcctttgg ggtgacgacg gcagatagcc gtaaggtgct ctctccagaa
    12901 tttaaagctg ttggggaaaa tatctactac atcccaggtc aagccctctc tgcagagatt
    12961 gattttgact tgattaagaa aaattttgct cagtttgaag caagccaagc tgaccataaa
    13021 gtgacatctg catcagctgt caaatacggt ggtgtagttg aaagtttggc tcttgctacc
    13081 tttggaaact atattggtgc agaggtgacc ttgcctgaac ttaaaacagc tttgacagct
    13141 caattaggcg gctttgtctt cacatctcct gaagaaattg ctggagtaga gaagattgga
    13201 caaacgaaag cagactttac actgactgtc aacggtgtga agctagatgg acacaagctt
    13261 gacagtgcat ttcaagggac attggaagaa gtttacccaa cagaatttac ccaagcgaaa
    13321 gaactagaag aagtaccagc tgtggtatca gatgttgtga ttaaagccaa agaaaaggtt
    13381 gaaaaacctg tggtttacat cccagtcttt ccaggaacca actcagaata tgattcagct
    13441 aaggccttcg aaaaagaagg tgcagaggtc aatttggtgc cattcgtgac cttgaatgaa
    13501 gaagctattg tcaagtcagt tgaaactatg gttgacaata tcgacaagac taatattctc
    13561 ttctttgccg gtggattctc ggctgcggat gaaccagatg gttcagctaa gtttatcgtc
    13621 aatatcctgc ttaatgaaaa agtgcgtgtg gctattgata gctttatcgc ccgtggtggc
    13681 ttgattatcg gtatttgtaa tggattccaa gccttagtca aatcgggtct cctaccatac
    13741 ggaaactttg aagatgctaa cagtactagt ccaaccctct tctacaatga tgccaaccaa
    13801 cacgtggcca agatggtgga aactcgcatt gccaatacca actcaccatg gttggctggt
    13861 gtgcaagtgg gcgatatcca cgctattcct gtttcgcacg gtgaagggaa gtttgtcgtg
    13921 acggctgagg aatttgcaga gctccgtgac aatggacaaa ttttcagcca atacgttgac
    13981 tttaacggta aaccaagtat ggattctaag tacaatccga atggttctgt ccatgccatc
    14041 gaaggaatta ccagcaagaa tggtcaaatc atcggtaaga tgggccactc agaacgttat
    14101 gaggatggtc ttttccaaaa tatcccaggc aataaagacc aacacctgtt cgcatcagcg
    14161 gttaaacatt tcactggaaa ataagactta cagattttct aatagatagt atcagtaatg
    14221 taaaagtcat gtaaatctag ctcttgatga ttacaaatga aaattaggta taaaaaatga
    14281 catacgaagt aaaatctctt aatgaagaat gtggtgtttt cggtatttgg ggacatccag
    14341 atgctgctaa gttgacctat tttggactcc acagtcttca acaccgtggt caggaggggg
    14401 caggaatcct ctccaatgat caaggacaac tgaagcgcca tcgtgacatg gggcttttat
    14461 cagaagtttt cagaaatcca gccaatttgg ataaattgac aggagctggt gcgattgggc
    14521 atgtgcgtta tgcgactgct ggcgaagctt ctgttgataa catccagccc ttcctcttcc
    14581 gttttcacga tatgcagttt ggcttggctc ataatggaaa tctgaccaat gcagcctctc
    14641 tcaagaaaga actggaacaa agaggagcaa ttttcagcgc gacttcggac tctgaaatct
    14701 tggctcacct cattcgtcgt agtcataatc ctagcctgat gggcaaaatc aaggaagcgc
    14761 tcagccttgt caaaggtggt tttgcctata tcttgctgtt tgaggacaag ttgattgcgg
    14821 ctcttgaccc taatggcttt cgtccgcttt ctatcgggaa aatggccaac ggagcggtgg
    14881 ttgtttcctc tgaaacctgt gcttttgagg tcattggtgc cgagtggatt cgtgatttga
    14941 agccaggtga gattgtgatc attgatgacg agggcattca gtatgacagc tatacagatg
    15001 atactcagtt ggcgatttgt tctatggagt atatctactt tgctcgccct gattctaata
    15061 tccacggtgt caatgtccat acggcacgta agagaatggg agcgcaattg gcgcgagaat
    15121 ttaagtatga ggcagatatt gtagttggtg tgcccaattc ttccctaagc gcggctatgg
    15181 gatttgcgga agaatcaggc ttaccaaatg aaatgggtct gatcaaaaac caatacaccc
    15241 agcgaacttt tatccaaccg actcaagaat tgcgggagca aggagtgcgg atgaaactgt
    15301 ctgctgtttc gggtgttgtc aaaggcaaac gtgtggtcat ggtggatgat tccattgtac
    15361 gtggaacaac ctctcgtcgt atcgttcagc tcttgaaaga agcgggtgcg actgaggttc
    15421 acgttgccat tggaagtcct gcactagcgt atccatgttt ctacgggatt gatatccaga
    15481 cccgtcagga gctgattgca gccaatcata cggtcgaaga aactcgccaa atcattggtg
    15541 cggacagtct gacttatctt tcaattgatg gcttgattga gtcgattggt atcgaaacag
    15601 atgcgccgaa cggtggtctc tgtgtcgctt actttgacgg tgactaccca acgcctctct
    15661 atgattacga agaagactat cgtagaagtt tggaagaaaa gaccagtttt tacaagtagg
    15721 cgacagattc tccattaaag aaaaggaaaa aacaaatgac aaataaaaat gcatatgccc
    15781 agtcgggtgt ggatgttgaa gcgggttatg aagttgttga acggattaaa aagcacgtgg
    15841 cccgtacgga gcgtgcaggt gtcatgggag ctcttggtgg ctttggtggt atgtttgacc
    15901 tttccaagac tggggttaaa gaacccgtct tgatttcagg gactgacggt gtcggaacca
    15961 agctcatgtt ggctatcaag tacgacaagc acgataccat cgggcaggac tgtgtggcca
    16021 tgtgtgtcaa cgacatcatt gctgcaggtg cggaacccct ctattttctc gactacgtag
    16081 cgacagggaa gaatgaacca gctaagctag aacaagtggt tgctggtgtg gcagaaggtt
    16141 gtgtgcaggc tggtgctgcc ctcatcggtg gggaaacggc tgaaatgccg ggcatgtacg
    16201 gcgaagacga ctatgacttg gctggttttg cggtcggtgt ggctgaaaaa tctcaaatca
    16261 ttgacggttc aaaggtggta gagggagatg ttcttctcgg acttgcttca agtgggattc
    16321 actcaaatgg ttactctttg gttcgtcgtg tctttgcgga ttacacaggt gaggaagtcc
    16381 taccagaatt ggaaggcaag aaacttaagg aagttctact tgagccgact cgtatctatg
    16441 tcaaggctgt cttgccgctc atcaaagaag agttggtcaa cggcattgcc cacatcacag
    16501 gtggtggctt tatcgaaaat gtccctcgta tgtttgcaga tgacctagct gctgaaattg
    16561 atgaaagcaa agttccagtg cttccaattt tcaaagccct tgaaaaatat ggtcagatta
    16621 aacacgaaga aatgtttgaa atcttcaata tgggtgtggg acttatgttg gcggtcagcc
    16681 ctgaaaatgt agagcgtgta aaagaattgt tggatgaagc agtctatgaa attggtcgca
    16741 tcgtcaagaa agaaaacgaa agtgtcatta tcaaatgaaa aaaatagcgg tttttgcctc
    16801 tggtaatggc tcaaattttc aggtgattgc cgaagaattt ccagtggagt ttgtcttttc
    16861 agaccatcgt gatgcctatg tgcttgagcg tgcaaagcag ctcggcgttc tgtcctatgc
    16921 ttttgaactc aaggagtttg agagcaagac agactacgaa gcagcccttg tcgaactctt
    16981 ggaagaacac cagattgact tggtttgcct agcaggctac atgaaaatcg ttggaccaac
    17041 cttattgtcg gcttatgaag gtcggattgt caacattcat ccagcctact tgccagaatt
    17101 tccaggagct catgggattg aggatgcttg gaatgctggc gtgggtcagt ctggtgtgac
    17161 cattcactgg gtggattcgg gtgtggatac aggccaggtc atcaaacagg ttcgtgtgcc
    17221 acgactagct gatgatacca ttgacagatt tgaagctcgc atccatgaag cagagtacaa
    17281 gttgtatccg gaagtagtga aggctctatt tacagattga ctttttgatg attcatatga
    17341 tatctttgat tttaaattgg agtcagtgtt tgttgaagac ggcttcaaac ggaggtattt
    17401 gtaatgttag aatctaaaaa aacaactcga tatgtatttt atgtctatct gatgttatta
    17461 acttggggaa tcttatttaa gtttgaaaca aatcctgaat ttatagcatt tttcttagct
    17521 ccaaggtata tcaattggat tccattttca gaaccactaa tagtcgatgg aaaaattgtt
    17581 tttgctgaaa tgttatttaa tctgatttcc tttattccat taggtgtttg tttccctttg
    17641 ataaaaacta atttatctag tttaagaata gtcgggacag gtttcttgat tagtttattg
    17701 tttgagtgct tacagtatat tttagcaata ggtataacag atataacgga tttgacttta
    17761 aatacgctag gtgtctgtgt aggcttactg atttatcaaa tttttataag agtgttcaaa
    17821 tcacagacta gaaaatggat caatatctta ggtatgctta gccttggttt tgcttatctt
    17881 gttttactgt tactgcattt aattggtgtt taactaatga ttaaaaagga gaatataatg
    17941 actaaacgcg tcttaatcag cgtctcagac aaagcgggca ttgttgaatt tgcccaagaa
    18001 ctcaaaaaac ttggttggga gattatctca acaggtggaa ctaaggttgc ccttgataat
    18061 gctggggtgg ataccattgc tatcgatgat gtgactggtt tcccagaaat gatggacggt
    18121 cgtgtgaaga ccctccaccc aaatatccac ggagggcttc tcgctcgtcg tgacttggat
    18181 agccacttgg aagcggctaa ggacaacaag attgagctca ttgaccttgt ggtggtcaac
    18241 ctttacccat ttaaggaaac tatccttaaa ccagatgtga cttatgctga tgcagttgaa
    18301 aatatcgata ttggtgggcc atctatgctt cgttcagcag cgaaaaatca tgccagtgtt
    18361 acagttgtgg tagatcctgc tgactacgct gtggttttgg acgaattggc agcaaacggc
    18421 gaaacctctt atgaaactcg ccaacgttta gcagccaaag tatttcgtca cacagcggct
    18481 tatgacgcct tgattgcaga atacttcaca gctcaagtgg gtgaaagcaa gcctgaaaaa
    18541 ctcactttga cttatgacct caagcaacca atgcgttacg gtgagaatcc tcaacaagac
    18601 gcggactttt accagaaagc tttgcctaca gattactcta ttgcttcagc caaacagctc
    18661 aacgggaaag aattgtcatt taataatatc cgtgatgcag atgctgctat ccgtatcatc
    18721 cgtgacttca aagatagtcc aaccgttgtg gctctcaaac acatgaatcc atgtggaatt
    18781 ggtcaagctg atgacatcga gactgcttgg gactacgctt atgagtctga cccagtatct
    18841 atctttggtg ggattgtcgt cctcaaccgt gaggtggatg ctgcgacagc tgagaagatg
    18901 cacggcgttt tcctcgaaat catcattgca ccaagctata cggatgaagc gctagctatt
    18961 ttgatcaata aaaagaaaaa cttgcgtatc cttgccttgc catttaatgc tcaagaggct
    19021 agcgaagtgg aagcagaata cacaggtgta gtcggtggac ttctcgtgca aaatcaagac
    19081 gtggtcaagg aaagcccagc tgactggcaa gtggtgacca aacgtcagcc aactgagaca
    19141 gaagcgactg ctcttgagtt cgcttggaag gctatcaagt acgtcaaatc aaatggtatt
    19201 atcgtgacca acgaccacat gacacttggt gttggtccag gtcaaaccaa ccgtgtggct
    19261 tctgttcgcc ttgccattga ccaagccaaa gatcgtctga acggggcggt ccttgcttca
    19321 gatgccttct tcccatttgc ggataacgtg gaagaaatcg ccaaagcagg aattaaggcc
    19381 atcatccagc ccggtggctc tgtccgtgac caagaatcca tcgaagcagc ggataaatac
    19441 ggcttgacta tggtctttac aggtgtgaga cattttagac attaagaaga taaaagggaa
    19501 gaaaacagtt tctttccttt tttggcttaa aatgctaact gaaacaagat taaaacgaac
    19561 ttttttgata taatgttggt aaataattcg caaaagaggt tgaggaatga aactgcttgt
    19621 tgtcggttct ggtggtcgtg agcatgcgat tgctaaaaag ttacttgaat caaaagacgt
    19681 ggaaaaagtc tttgtagctc ctgggaatga tgggatgact ctggatggtt tggaattggt
    19741 aaatatctct atttccgaac attctaaatt gattgacttc gcaaagacca atgatgttgc
    19801 ttggaccttt atcggtccag atgatgccct tgctgctggt atcgtggatg attttaacca
    19861 agctgggctt aaggcctttg gtccgactag gactgcagcg gagctggagt ggtccaagga
    19921 ttttgccaag gaaatcatgg tcaaatatgg tgtttcgaca gcagcctatg gcacattttc
    19981 agatttcgag gaagcaaagg cctatatcga aaagcatggt gcgcctatcg tagtcaaggc
    20041 ggatggcttg gcgcttggga agggtgtcgt cgttgctgag acggttgagc aagcggtcga
    20101 agccgctcat gagatgcttt tggacaataa atttggtgac tcaggtgcgc gcgtggttat
    20161 tgaggaattc cttgaaggag aggaattttc actctttgcc tttgtcaatg gtgataagtt
    20221 ctacatcatg ccaacggctc aggaccacaa acgtgcctac gatggcgaca aagggcctaa
    20281 cacgggtggt atgggtgcct atgcgccagt tccacactta ccacagagtg tagttgatac
    20341 agcggttgac atcattgtca agccagttct agaagggatg attaaagaag gtcgccctta
    20401 tctgggagtt ctttacgcag ggcttatcct gacagctgat ggaccgaaag tcattgagtt
    20461 caacgctcgg ttcggagatc cagaaactca gattatcttg cctcgcttga cctctgactt
    20521 tgctcaaaat atcacagata ttctggatgg caaggagcca aatatcatgt ggacggacaa
    20581 gggtgtgact ctgggtgtgg ttgtcgcatc caagggctac ccgctagact atgaaagggg
    20641 cgttgagttg ccagccaaga cagaaggcga tgtcatcacc tactatgcag gggctaagtt
    20701 tgcggaaaat agcagagcac tgctctcaaa cggcggacga gtttatatgc tcgttaccac
    20761 agcagatacc gtcaaagaag cccaagccag catctaccaa gaactatccc aacaaaaaat
    20821 agaaggactc ttctaccgaa cagatatcgg aagcaaggca attaagtaaa gatataagaa
    20881 taacgcgccg tagtcgccaa acacgataat ggtcgtcgtg gtgaaaagac cagaacagtg
    20941 aatgttctgg tcagggggaa acttggagac cgtaggctca aagtttagga atgaaaccga
    21001 aggtttgctt ccgcctccat cacctaagac cattatcaaa aagaaaaata aaaattcaca
    21061 aaatacgtta atggtcgtat ggtttgcgag cgttagcgag ctaatataga ataatcaccg
    21121 ccgttgtgaa agaacgattg gatgaccttg ggtttccaat ttaggcatga gacacctttg
    21181 gtggctgctg ccgtccctca caagctaagg tgattgttga aaaagaggaa aaaggagaag
    21241 aaatgaaacc agtaatttcc atcatcatgg gctcaaaatc cgactgggca accatgcaaa
    21301 aaacagcaga agtcctagac cgcttcggtg tagcctacga aaagaaagtt gtttccgcac
    21361 accgcacacc agacctcatg ttcaaacatg cagaagaagc ccgtagtcgt ggcatcaaga
    21421 tcatcatcgc aggtgctggt ggcgcagcgc atttgccagg catggtggct gccaaaacaa
    21481 cccttccagt cattggtgtg ccagtcaagt ctcgtgctct tagtggagtg gattcactct
    21541 attctatcgt tcagatgccg ggtggggtgc ctgttgcgac catggctatc ggtgaagctg
    21601 gagcgactaa cgcagctctc tttgccctcc gtctcctttc tgtagaagat aagtccattg
    21661 cggatgcact tgccaacttt gctgaagaac aaggaaaaat cgcagaggag tcgtcaaatg
    21721 agctcatcta aaacaatcgg aattatcggt ggcggtcaac tgggtcagat gatggccatt
    21781 tctgctatct acatgggcca caaggttatc gcgctggatc ctgcggcgga ttgcccggcc
    21841 tctcgtgtgg cggaaatcat tgtggcacct tataacgatg tggacgccct ccgtcagttg
    21901 gcagaccgtt gcgatgtcct cacttacgag tttgaaaatg tcgacgctga cggtttggat
    21961 gccgttatca aggatggaca actccctcaa gggacagacc tgctccgcat ttcgcaaaat
    22021 cgtatttttg aaaaggactt tttgtcaaac aaggccaaag tcaccgttgc accttacaag
    22081 gttgtgacct caagccaaga tttggcagat atcgacttgt cgaaaaacta tgtcctcaag
    22141 attgcgactg gtggctacga tggtcatgga caaaaggtta ttcgttcaga agcagacttg
    22201 gaagcagcct atgcgctagc agactcagca gactgcgtct tggaagaatt tgtcaacttt
    22261 gaccttgaga tttctgtcat cgtgtcagga aatggcaagg aggtgacgtt tttcccagtt
    22321 caggaaaata tccaccgcaa caatatcctg tctaagacca ttgtaccagc ccgtatttct
    22381 gaaagtctag cagacaaggc taaagctatg gcagtgcgaa tcgcagaaca actcaacttg
    22441 tctggaactc tctgtgtgga aatgtttgcg acagctgatg acatcattgt caatgagatt
    22501 gctccacgac cacacaactc aggccactac tctattgaag cctgtgactt ttcacaattt
    22561 gacacgcata tattaggtgt tctgggagca ccattgccag ccataaaact acatgtgcct
    22621 gccgtcatgc ttaacgttct cggtcagcat gttgaggtcg ctgagcaata tgtgacagaa
    22681 aattcaagcg cccacctcca catgtatggt aaaatagaag caaagcataa tcgtaagatg
    22741 ggacatgtga ccttgtttag cgatgtaccg gatagtgtgg atgagcttgg ggaagggatt
    22801 gatttttagg acaagtctat gatacaaatt atcgttaata catttattga aaaggataag
    22861 actggagcag ttgttgaagt gttgtatgcc agtgctgacc aagataaggt acaagctaaa
    22921 tatgaagaac tagctgcaca ataccccgaa aattatttag ctatctatga tgtaccgctg
    22981 gatacggatt tgaatacact agatcattac ccgtctgtgt ttattggaaa agaggagttt
    23041 gagtagaaat cttggtttac ctagatagct tattcccaac agcttaagaa gaaaggaaaa
    23101 attaacacat gatcaaccgt tactctcgcc ctgagatggc gaatatttgg agtgaagaaa
    23161 ataaataccg tgcttggctt gaggtggaaa tcctctctga cgaggcatgg gctgagttgg
    23221 gggaaatccc taaggaagat gtggctttga ttcgcaagaa ggcggacttt gacatcgacc
    23281 gtattttgga aattgagcag gagacgcgcc acgatgtggt ggctttcacg cgtgcggttt
    23341 ctgagactct tggtgaagag cgcaagtggg ttcactatgg gttaacttct actgacgtgg
    23401 tggatactgc ttatggttac ctctacaagc aggccaacga catcatccgt cgtgaccttg
    23461 aaaacttcac taatatcatc gctgacaagg ccaaggagca caagttcacc atcatgatgg
    23521 ggcgtactca tggtgtgcac gctgagccga caacctttgg tcttaaatta gcaacttggt
    23581 acagcgaaat gaaacgcaat atcgagcgct tcgagcatgc ggctgctggt gtagaagctg
    23641 gtaagatttc tggtgcggtt gggaattttg ccaatatccc accatttgta gaggagtatg
    23701 tctgcgataa acttggcatc cgtgcccaag aaatctctac acaagtcctt cctcgtgacc
    23761 ttcacgctga gtactttgcg gttcttgcca gcattgcgac ttcaatcgaa cgtatggcga
    23821 ctgagattcg tggtctacaa aaatctgagc aacgcgaagt agaagagttc tttgctaaag
    23881 ggcaaaaagg gtcttcagca atgcctcaca aacgcaaccc aatcggttct gaaaatatga
    23941 ctggtctggc gcgtgtcatt cgtggtcaca tgattacggc ttatgaaaac gtcgctctct
    24001 ggcacgaacg cgatatttct cactcatcag ctgagcgtat catcacacca gatacgacca
    24061 ttttgattga ctacatgctc aaccgttttg gaaatatcgt caagaacttg acagtcttcc
    24121 cagaaaatat gatccgaaac atgaactcga cttttggtct tatctttagc caacgggcta
    24181 tgttgacatt gattgaaaaa ggcatgaccc gtgagcaagc ctatgacttg gtgcaaccaa
    24241 aaacagccta ctcttgggac aaccaagtag actttaaacc acttcttgag gcagattcag
    24301 aagtaacatc acgtctcact caagaagaaa tcgatgaaat cttcaaccca gtttattaca
    24361 ccaaacgagt ggatgatatc tttgaacgtc ttggactagg tgattaatta aaaaataaac
    24421 agcgagcttc aatctcgctg tttatttttt atcgaaaaga cttagtcttc ttttctttta
    24481 gtgagtccat aggctgctag tgtggccatg agtcctgcga ctactagtcc tgcagaatcg
    24541 tgagttcctg tttcaggaag ttttttctct attaccacag gagctggatt ttgaggaaga
    24601 gctttgcttt cctcagcagg agcagttgat ggagctggtt ggcttgggat ttctagtttt
    24661 gatttttctt cagcaatagc ggcttgtccg ttttcatcgc ctacatgtgt taccatagtt
    24721 ccgacttcga ctatttgagt aacggcttcc tgtgctacga cactatttac aagtgttttc
    24781 acttccttac catcggcaga agtgctcaca gagtagaagt tgctacgatg tccattgacg
    24841 cccttagtaa tgacttgtgt ttttcctttg agtaagagtg gattttcacg agtcactgtg
    24901 gtaaatggaa tttcttcttt ttggatatcc agtctaggtt ttacctcagt agttggtgca
    24961 agaccacttt catcaccctt gtgagttaca ggagcgccaa cttcaaccac ttggtttata
    25021 acttctttgg ttacctggct atcaaggact gtttctgttg tttttccatt ttcagtgagt
    25081 acagagatgt aatgagttcg ttcacctttg actcctgctg tgataatatt ttcttgacca
    25141 gctgggaggt taggattttc tttcttgata acttcaaatg gaatttcttc agttcttgtg
    25201 atgagttctg gtctggtttc aacattggca gccacttcat tttcatctag gcttcctgaa
    25261 tgagttgcag ctggtttgag gccttgaaga gcggctttta ggttggctac aagtgtgtca
    25321 agctcagctt gtttattacg gttgaggttg taatttagag ctgttttagc tgcgtcaagg
    25381 gcctcaagac tttctttact atatccttct aagtttgtag gaattttagc taattcttcg
    25441 cggagagcat tataattagc acggaagtag tctttgttgt ggtctgcaaa ggcagtcatg
    25501 agttcaaaga tttcctcttc cttgtattca gcgcttggtc tatctgccca gattgaaagc
    25561 atacttccga ctgttggaag atctacttca ggatatttgg tagaagctag ttgattgaat
    25621 ggaactttac cagaattttc aactgctttt gaaagagggt aagcttcctc ttgtttgtga
    25681 ttgcctataa cataatacca gtcaccgttg gtattcaaga atttatagcc tttgcttgct
    25741 aggtattgag gtgatgcgag gttatatccc caccagcctt tagaccagta agaaatcaag
    25801 acatctttgt caaactgaac atcgtccttg tcttcatagt agaagccatc gttgaaggcc
    25861 attggttgaa gccctctttc tttggccata gctgcgaggg tgttggcata ttcggcaaat
    25921 ttgccataga gttgatacca cttgaggtag taccagcctt gggcactagt cgcatcgttg
    25981 gcgtattcgt cagtaccaaa gttgaaaatc tttgttttac ctgcaaagaa gtccatgtat
    26041 ttaccgatga gggcttttac aaagtccatc gcttcttcgt ttttcaagtc catagttgtt
    26101 tttgaaactt tatcaaagtg ggcttgagga tttttaatac ctaatttttc catggcaacc
    26161 agcatagcat ccatgtgacc tggactgtta atagctggga tgagaccgat gtccttagat
    26221 ttagcgtatt caattagctc tgtcacttct gcctgtgtta gtgcagtacc gtttggatcg
    26281 tcgtagtaag ctttagttcc ttcgataata gcttttttaa cgtcatcact agcataggtt
    26341 tttccgttgg cagtaatggt catatcattg agtagaaagc gaagtccgtc atttcctaga
    26401 aggagatgga catcagaata tccgagctca ctggccttgt ctacgatgcg tttgagctgg
    26461 ttcagagtaa agtatttgcg tccagcatcg attgagatta ccttgttttt ggcaagtttt
    26521 tcaacctcac gtttagcttc ttcttctttt tgagcttcag gcgtgagggt caagttgttg
    26581 acagtttctt gaagtttagc aatggcttga tcaatcgtat cttgttgggc acggctaagg
    26641 ttgctatcga gagagcgaat agctttttca gcttctttta cggccgcgac gctttctgca
    26701 gtataacggt tcaggtcttt tggtacctcg ttaagtgctt gctctgcaga ttcataatca
    26761 gctgcgaagt attcagcgtt ggcatttgca aaatgacgca tgagtttgaa gaggcgtgat
    26821 ggtgaataac gtgcagatgg agtgtcagcc caagcagcta ccataccacc gatgattggg
    26881 atatcagctc cttctgtttt tggtacagaa gtgattggtg tgtttttaat accattgagc
    26941 ccctgatcga gattgtacca gccttggcca tcagcgtttc gtccaagaac gtagtaccaa
    27001 gcatcattgg tattaaggat ttggtgacct ttttcagcta gtagtttaga agaagcgaca
    27061 tcgtagcctc cccaaccacc agtccacata gaaacgatga tgtctttgtc aaaactacca
    27121 aagcttgtgt cgctattgta gtagataccg tcgttaaagg ccattggttt gagaccgtgc
    27181 gattttacaa tacgagcgag gtcattggcg taggcaataa atttttcata gccttttaca
    27241 gggtagcctt cgtttggata gtatttatca gcttgaagca cactccaacc tttagcatct
    27301 gtcgcatcat tggcatattc atcaagtccg atgttgaaga tttcagtctt tttcgcgaaa
    27361 taagcagcat acttgtcgat aagggctttt gtaaaagcga cagcttgttc gttgtcaaga
    27421 tcgacagtac gggctgattt cttcccaaaa tagctaaagt tagggttttg gattcccaat
    27481 tctttcatgg cattgagaat cgcatccatg tgtccaggac tatttactgt cggaatgaga
    27541 ccgatacctt tatctttggc atagttaatc agatctgtca tttgactttc tgttaagtga
    27601 ttgccgtttg gatcgttgta ataatcattt gtaccttttt caatggcgcg tttgacatcg
    27661 tcactggcat aggtcttgcc gttagctgtg atgctcatat cgtccaacat gaaacggagt
    27721 ccatcatttc cgactaatag gtgtaaatca gtgtagccat aatgtttcgc tttatcgatg
    27781 atttccttga gctgttctgg tgagaaatat ttacgtccag catcaataga aacaattttc
    27841 tttttcgcta gtttttcatt tacagttgca gcacgttcct ttcctgcctc tgtttccggt
    27901 ttgtcagcct ctgctttcgc ttcatctttt ttagctggtt tatccttgtc agtcttgtct
    27961 gtatttgact ctttagaatc aacctctttc gcttcttcct ttttagggct agcttcttct
    28021 gcctttttat tagcagtttc tttttcagca gaagttggag ttaccacttc tgctttatca
    28081 ctaggagttg aactaacttc ctcttgtggt ttttcttctg tttttggaag actagctacc
    28141 ttatcagtag ctggagtttc tgtttctaca gtttttggag cttctggttg aagcactgct
    28201 ttaggtgttt cctcagtccg attttcggat gattgagggg aatcagaaac cgtatggatg
    28261 gtcggttggt tttctgtagt agtaggagta actccatcgg ctgcaacagt ctgtgcttgg
    28321 aaggcaaatc caattagaac agaagctgct cctacagcgt atttacgaat agaaaaacgc
    28381 tgttgttttt catgtttcat tgcaaaacct cctgattgca ttgttatatt gatagcgatt
    28441 atataaatca acgcccttat tttatttctt atattaacga gagtcaagag gagatgacaa
    28501 aaaactataa taagtataaa aaaatataaa atttaaactt aagatttcag attggtcgga
    28561 aaaaatgcat atatatatct agtataattt ttggttctat ttctataaaa tattccacaa
    28621 attatagaat cttccaaaaa taggtaagcg ctaccttttt ggtgtggtat aataagcata
    28681 gaaaaagccc gagcgattag gctcaggttt tcttcttagt gatcacggtc acatgagata
    28741 aatttaatct tgtagtaatc agatcgtttg taagtttcac tgtattctaa aacttggcca
    28801 gttgattcga gtttggtgat tttagtttgt aggacagtag ggaattgttc atcgactccg
    28861 aggactgaag ccgcatgttc tggagttgga aagactattt cgttgatttc ttcaaagtgt
    28921 tcatcattca tgtgaatgtg gtagtctaac ttgaaacgat tatagataga actatagtat
    28981 tcaaggtttg gataatttgc gttgatatat tgttctggga tgtaggatgt atggtagata
    29041 taaacgacac cgtttgattc gcggatacgt tcaatcttgt agtagaattg atcgccgcgt
    29101 agacccaatt tttccaagta aacaagcttg tttccgcgtt caattgaaag aacagttacc
    29161 ttatcatctt tagcattgaa gagctcaata tctgaaaact ctacaagctt gtgtttgcgt
    29221 gcacgtgaaa cgaaggttcc ttttccttgt tggcggacaa tatagccatc tttggcaagg
    29281 tcgtttaagg cgcgaacaac tgtgatagag ctgacatcgt acattgaaat gagttctgct
    29341 tcagtgtaaa atttatctcc actgctaaac tgcccagaga tgattttatt ttttaattcg
    29401 tcttttatgt attgatattt gggaattgcc atatttttac ctctattttc cttctccata
    29461 gaaaatttta ccataaaagc gaaaaaaata gtagtctttt gaataaaaaa ttagaataat
    29521 agtttgaaaa attaagcgat atagggattg ctcatatttt atcaatgtat tctatacaaa
    29581 attattttag gtcctatatt ccgaatttaa agagcgtttg aaatgggtct aaaaatgttt
    29641 gaaactaatt gaatatgtgt ataatagtaa aaatgcagta aatatcccga catttctatt
    29701 gacaattcaa acagattggt ttataattaa tataacaaca aatgaaagcg caaactttcg
    29761 cggtcggaag gtagttttat gacacgattt gagatacgag atgatttcta tctcgatgga
    29821 aaatcattta agattttatc tggtgccatt cattatttta gggttcctcc agaggattgg
    29881 tatcattcgc tctataactt gaaggctctt ggttttaata cggtagagac ttatgttgct
    29941 tggaatttac acgagcctcg tgaaggtgag tttcattttg acggtgatct ggatttagag
    30001 aaatttctcc aaatagcgca ggatttgggt ctctacgcaa ttgtgcgtcc gtctccattt
    30061 atctgtgcgg aatgggaatt cggtggctta ccagcttggc tcttgaccaa gaacatgcga
    30121 attcgctcat ccgacccagc atatatcgag gcagttggtc gctactatga tcagttattg
    30181 ccaagactgg tgcctcgttt gttggacaat ggtggcaata ttctcatgat gcaggttgaa
    30241 aatgagtatg gttcttacgg agaagataag gcttacctga gagcgattcg acagctaatg
    30301 gaagagtgtg gcgtaacctg tcccctcttt acatcagatg gtccatggcg agctactctg
    30361 aaagctggaa ccttaattga agaggacctc tttgtaacag gaaactttgg ttctaaggca
    30421 ccttacaact tttcgcagat gcaggaattc tttgatgaac atggtaagaa atggccactc
    30481 atgtgtatgg agttctggga tggttggttc aatcgctgga aagaaccgat tatcacacgg
    30541 aatcctaagg aattggcaga tgcagttcga gaggttttgg aacaaggctc tatcaatctt
    30601 tacatgttcc acggtggtac aaactttggt ttcatgaatg gttgctcagc tcgaggaact
    30661 ttggacctgc cacaagttac gtcttatgat tacgatgccc ttctggatga agaaggaaat
    30721 ccaactgcta aatatcttgc agtcaagaag atgatggcaa cacatttttc agagtatccg
    30781 cagttggaac cactctacaa agagagtatg gagttggatg ctattccact agttgaaaaa
    30841 gtttctttat ttgaaacctt agatagcttg tcaagtcctg tagaaagtct ctatcctcaa
    30901 aagatggagg agctgggaca aagttatggc tacctacttt atcgaacaga aacaaactgg
    30961 gatgcagaag aagaaagact tcgtatcatt gatggtcgag atagggccca gctgtatgtc
    31021 gatggtcagt gggttaaaac tcaatatcag acagagattg gggaagatat tttttatcaa
    31081 ggtaaaaaga aagggctatc taggttagat atcttgatag aaaatatggg gcgtgtcaac
    31141 tatgggcata agttcttagc ggatacgcaa cgtaagggaa ttcggacagg ggtctgtaag
    31201 gatctgcatt tcttactaaa ctggaaacac tatccactcc cactagacaa tcctgagaaa
    31261 attgattttt caaaaggatg gactcaagga caaccagcct tttacgctta tgactttaca
    31321 gtcgaagagc caaaagatac ttacctagac ttgtctgagt ttggtaaggg ggttgccttt
    31381 gtcaatgggc agaatctagg acgtttttgg aacgttggcc caactctctc actttatatc
    31441 cctcatagct atctcaagga aggtgccaac cgcatcatta tctttgaaac agaaggtcaa
    31501 tataaagaag agattcattt aactcgtaaa cctacactaa aacatataaa gggggaaaac
    31561 ttatgacaat tgtaggatgc cgtattgatg gacgtttgat ccacggacaa gtagccaatc
    31621 tttgggctgg aaaactaaat gtttcacgca ttatggttgt agacgacgaa gttgtcaaca
    31681 acgatattga aaagagtggt ttgaaacttg cgacaccacc aggtgtgaaa ttgagtattt
    31741 tgccagttga gaaagctgca gccaatattc ttgctggcaa atacgatagc caacgtctct
    31801 ttatcgtggc tcgtaaacca gaccgcttcc ttggtttggt agaagcaggt gtaccacttg
    31861 aaactcttaa tgttgggaat atgtctcaaa caccagaaac tcgttctatt acacgttcta
    31921 tcaacgtagt agacaaggat gtggaagact tccacaaact ggcagaaaaa ggtgttaaac
    31981 ttactgctca gatggttcca aatgatccaa tttcagactt tttgagctta ttaaaatagg
    32041 aaaaaaattt ttaggaggtc attgttatga tacaatggtg gcaaatttta cttctcactt
    32101 tgtactcagc ttatcaaatc tgtgatgagt tgacgatcgt ttcatctgca ggttcccctg
    32161 tatttgctgg tttcattact ggtttaatca tgggagatgt gactactggt ttacttatcg
    32221 gtggtaactt gcaactgttc gttcttgggg ttggtacctt cggtggtgct tctcgtatcg
    32281 acgcaacttc tggtgcggtt cttgcgacag ccttctctgt ttcacaagga attgatgcac
    32341 cgcttgccat tactacaatc gctgtaccag tagctgctct cttgacttac ttcgacgttc
    32401 ttggtcgtat gactactacc ttcttcgctc accgtgtgga tgctgcaatc gaacgctttg
    32461 actataaagg tattgaacgc aactacttgc ttggtgcgat tccgtgggct ctatctcgtg
    32521 cccttccagt cttctttgcc cttgcttttg gtggtgcctt tgtacaatca gtagtagact
    32581 tcgttgaagc ctacaaatgg gttgcagatg gcttgacact tgcaggacgt atgcttccag
    32641 gtcttggatt tgcaatcttg cttcgttacc ttccagttaa acgtaacctt cactaccttg
    32701 ctatgggatt tggtttgaca gctatgttga ctgttcttta ctcatatgta acaggtcttg
    32761 gtggcgctgt tgctggtatc gtaggtactc ttcctgctga agttgctgaa aaaattggtt
    32821 tcgtgaacaa cttcaaaggt ttgtctatga ttggtatttc tatcgtaggt attttccttg
    32881 cagtgcttca cttcaaaaat agccaaaaag tagctgtagc agcaccttct acaccatcag
    32941 aaagtgggga aatcgaagat gacgaattct aattacaaac ttacaaaaga agattttaat
    33001 caaatcaaca aacgtagctt gtttactttc caattaggtt ggaactacga acgtatgcaa
    33061 gcttctggtt acctttacat gatcttgcct cagttgcgta aaatgtatgg tgatggaact
    33121 cctgaattga aagaaatgat gaaagttcat actcaattct tcaatacttc accattcttc
    33181 cataccatta tcgctggttt tgaccttgcc atggaagaaa aagatggtgt aggttcaaaa
    33241 gacgccgtta acggtatcaa gacaggtttg atgggaccat tcgctcctct tggggataca
    33301 atctttggtt cacttgtacc tgctatcatg gggtcagtcg cagcaactat ggctatcgct
    33361 ggccaacctt gggggatctt cctttggatt gcagttgcag tagcgtatga catcttccgt
    33421 tggaaacagt tggaatttgc ttacaaagaa ggggttaacc ttatcaacaa catgcaaagt
    33481 accttgacag ctttgattga cgctgcatct gtacttggtg tcttcatgat gggtgctctt
    33541 gtagcaacag tgattaactt tgaaatttct tacaagttgc caatcggtga aaagatgatt
    33601 gatttccaag acatcttgaa ccaaatcttc ccacgtttgc ttccagcaat ctttactgcc
    33661 tttatcttct ggttgcttgg taaaaaaggt atgaactcta ctaaagctat cggtattatt
    33721 atcgtacttg ctttggctct ttctgccctt ggtcactttg cacttggaat gtaattcctt
    33781 atgactaaat cattaatttt ggtgagccat ggtcgcttct gtgaggagct tagaggtagc
    33841 acagaaatga ttatgggccc acaagacaac atttacacag tagctcttct tccagaagat
    33901 ggcccagaag aatttactgc taaatttgaa gctgttattg aagggttgga tgatttccta
    33961 gtctttgcgg atcttctcgg tgggacacct tgtaatgtgg tgagtcgctt gatcatggaa
    34021 ggtcgtgata ttgaccttta cgcagggatg aatcttccaa tggtgattga atttatcaat
    34081 gcgagcctta caggcgcaga tgcggactac acgagccgtg ctgcagaaag cattgtgaaa
    34141 gttaatgacc tgttagcggg cttcgatgat gacgaagatg aataatactc ttcgaaaatc
    34201 tcttcaaact acgtcaacgt cgccttgccg taggtatatg ttactgactt cgtcagtctt
    34261 atccggcaac ctcaaaacgg tgttttgagc tgacttcgtc agttctatct gcaacctcaa
    34321 agcagtgctt tgagcagcct gcggctagtt tcctatttta gttggaactc gattcaattc
    34381 atgtgacaac gtgaaaatcg ttagagcatt ttatatagaa tatacatggg aatgtagctt
    34441 actcccattc ccatatttaa tagaaaaaga ggaactcaat gctacattat acaaaagaag
    34501 acttgctcga attgggtgca gaaatcacta cgcgtgaaat ctaccaacag cctgatgtat
    34561 ggagagaagc ttttgaattt tatcaagcaa aacgtgaaga aattgcagcc ttcctacaag
    34621 aaatcgctga taaacatgac tatattaagg ttatcttgac aggtgctggg acttctgctt
    34681 atgtgggaga taccttgcta ccttacttta aggaagtcta tgacgaacgc aaatggaatt
    34741 tcaatgctat tgcgacaaca gatatcgttg ccaaaccagc aacctatttg aaaaaagatg
    34801 tggcaactgt ccttgtgtct tttgctcgta gtgggaactc gcctgaaagt gtggcgactg
    34861 ttgatttggc caaatccttg gtggatgagc tttatcaagt gacgattact tgtgcagcag
    34921 atggtaaatt ggctcttcaa gctcacggtg atgaccgtaa tctcttgctc ttgcaaccag
    34981 ctgtctctaa tgatgctgga tttgccatga cttctagctt tacgtctatg atgttgacag
    35041 ctctcttggt ctttgatcct acagaatttg ctgttaagtc tgaacgtttt gaagttgtat
    35101 ctagtcttgc ccgtaaagtt ttagacaagg cagaagatgt caaagagctc gttgatttag
    35161 actttaaccg tgtcatctat ctaggcgctg gtcctttctt tggacttgct catgaagctc
    35221 agctcaagat tttggaatta actgctggtc aagttgcgac catgtatgaa agcccagttg
    35281 gcttccgtca cggtccaaaa tctcttatca acgacaatac agttgttttg gtctttggta
    35341 caacgacaga ctacactcgt aagtacgact tggacttggt tcgtgaagtt gctggtgacc
    35401 agattgctcg tcgtgttgtg cttttgagtg atcaagcttt tggtcttgaa aatgtcaaag
    35461 aagtggccct tggttgtggc ggtgtcttga atgatattta ccgtgtcttc ccttacatcg
    35521 tttatgccca actctttgct ctattgactt cactcaaggt agaaaataaa ccagatacac
    35581 cgtctcctac aggtacagta aaccgtgtag tacaaggtgt cataattcac gaatatcaaa
    35641 agtaagacag cgtttatgaa ttcttgacaa gaggatttgt aaattatcag ataaaccata
    35701 gattgtcagt acgctttcta tggtttgttt gcttgagaga aatagtaaaa ggagaacaga
    35761 atgaaagcat acacagagcg tgtatttgga aatgttgagg gcgaggatgt cttggcctat
    35821 cgatttgaga cagacggtgg ctaccaactt gaggttatga cttatggcgc gaccatcttg
    35881 cgctatgtcg cacctgacaa ggctggaaat tttgccaatg ttatcttggg atttgatgac
    35941 tttgatagtt atgtaggcaa tagtcccaag catggagcaa gtgtaggtcc tgtagcgggt
    36001 cgtattgcag gtgcgacctt tgagctcaat ggtaagacct atgaccttga ggttaataat
    36061 gctagcaact gtaatcacag tggttcaact ggttgggatt ccagcttgtt tgaagttgaa
    36121 gaagtaagcg atcatggctt gactctctac acagagcgta cagatgggac aggagggttc
    36181 cctggaaatc tcaagatttg gatcagttat cacttggaag aaactggtgc ctatgaaatc
    36241 agctacaagg taacgaccga tcaggatacg ctggtcaatc caaccaacca cagctatttc
    36301 aacttgtctg gtgatttcac gcagacgatt gaccgtcatg tcttccaact aaacacagag
    36361 ggcatttact caatcgctcc tgacggtgtt cctgccaaaa ctccagaagc caaccgtgat
    36421 gtggtcaaac acatctacaa tggtaccttg ttgaaggata tctttgcaga agaagatgag
    36481 caaatccagc tggcatcagg tttggatcac ccatttgccc ttcctgtagg ccatgacaat
    36541 gctggattcc tttatgacca aaattcaggt cgcttcctgc ttttcaagac agaagctcct
    36601 tgctttgtgg tctacacagc aaactttgtg gatgaaagtg tcatcatagg aggtcagcca
    36661 atgctacagc acaatgggat tgctcttgaa gcgcaagctt taccagatgc cattcacagt
    36721 gacattaaag gccaagtcat tcttaaagct ggtcaaacct tcaccagtaa gacacgttat
    36781 gaacttgttg tgaaataaaa aagctggtca aaaagtcttt aaaattaaaa taacgcatat
    36841 tgtcaggtga tgaaaagttt gatactatgc gttttattat gaaatgattt actttatctt
    36901 atcctgaaat ggtgttattt ttgagttatc tggcttgact ttcttgatgg aaattatata
    36961 atagttgtaa taacaataat tacaacgaga aaagaggacc atttatgacc tatgaataca
    37021 agagtcacat ttatttggca gagacagttt taaatgtaaa ggatttggcc agtcaaacag
    37081 ccttttatca gcaagttatt ggtttagaaa tcttatctca aactgagaca gagtccattc
    37141 taggccttgg tggaaaagtc ttggtacagc tgattcaagc acaagagagc ggagaagtga
    37201 gggaacatta tggtctttac catttggcca ttctcttgcc cacacgcaag gctttggctg
    37261 atgttttgaa acacctgaca gatttgcaaa ttcctcttgt cggcggtgca gaccatggtt
    37321 acagtgaagc tatttacttg gaagatttgg agggaaatgg cattgaactc tatcgagata
    37381 agccagtttc cacatgggat attcgagaag atggacgcat tatcggagtg acggaggctc
    37441 ttgcggcgca ggacatttat gagttggggg aaagagtaga gccctttatc ctggcagaag
    37501 gtacaagaat ggggcatatt catctttccg tcaaggatag tcgaaagtcc agccagtttt
    37561 atcaaaaggt gttagggcta gagaataaat tcagtgtgcc tggcgctagt tggattgcgg
    37621 ctggagatta ccatcatcat ttagcagtta acgaatggag aggaaaaggt ctggcttcgc
    37681 gtaagcaagg cttaccaggt ttagcctact atgtcatcga agtcgcacat aaaaaagaac
    37741 tgttaacgat tgcccaacga gcacaagaag ttgacgcacc aatcaaatgg atgacatcga
    37801 gccaattgga aatcacagac tcagatggca tcgtgacccg tattcgttta gcaaggtaaa
    37861 attaggaatt tctaataagt tataagtatt gctagtttgc tttttgaacg gtctttggta
    37921 acagaactgc gtgagctgga tgggtgagaa ttttgacaaa gaagctgatt agagatataa
    37981 tgaagaaaaa tcgagcaagg aaaaagaaat gacaaattca aagtatatta cttgtttgaa
    38041 acgttcagag ggccagttgt gtgggattca aaagatgatt gaaggagatc gtgactgtgc
    38101 tgatattgtg acgcaactga cagcagtgag atctagtgta gagcgcgtga ttgagatgat
    38161 aattaccgaa aatcttactg aatgtatcaa tcagccgcta gatgattctg aagctcaaaa
    38221 ggaacgccta gaaaaggcta tccgatactt gattaaacgg aaataaatga atgttttgag
    38281 acgatatgtg caaaggtcta ttaactatta gaatagttta atgtgagtca aaagaagttg
    38341 taaaaaatct ttaaaattaa aaaaacgcat agtatcaggt gttgaatgta ctgaccccca
    38401 aaagttagat tttttctgtc taacttttgg gggtcagttc ataagaacct tggtaatatg
    38461 cgttttatta tgtagagact tatactcttc gaaaatctct tcaaaccaca tcagcttcac
    38521 cttgccgtag atatggttac tgacttcgtc agttctatcc acaacctcaa aacagtgttt
    38581 tgagctgact tcgtcagttc catccacaac cttaaaacag tgttttgagc agcctgcggc
    38641 taacttccta gtttgcactt taattttcat tgagtattac ttcatcttct catgaaattg
    38701 agtttttgcc cagctcctct tgattattct acttgaccgg gccaagtatt cataccacct
    38761 tctacgttgg taacggtgag gccttgggag ctgagaaatt ggcaggtaga tgcagagcgg
    38821 actcctcctt gacaaataac atagtattca tggtcaggtt tgagttcttt gtagccttgc
    38881 tctaaggtac ttaatggaag atttttggca cctggtgcat gtcctgcttg gaattcatgt
    38941 gcttcacgga catcgataag ttctagattt tcattttagt attttccata aaagtcagcc
    39001 atgctgatac tagtttccat attctactcc ttctgggtta gccattttgt atagtgaata
    39061 agcgccgtca aggttttgga cggtaaatcc tgcttgcttg aggataggct ctgcgatata
    39121 gctgcgcaaa ccactgtggc agctgacgat gtaggcttgt tttttgtcca gttcatcagc
    39181 ttcctccttg acactttgtc agtttttgat acaatagtac aaaattagag gaggtgggct
    39241 atgattcaga aacatgcgat tcccatttta gagtttgatg ataatcctca ggcggttatc
    39301 atgcccaatc acgaggggtt ggatttgcag ttgccaaaga agtgtgtcta tgctttttta
    39361 ggtgaggaga ttgaccgcta tgcgagggaa gtaggggcga actgtgttgg cgaattcgtt
    39421 tctgctacca agacctatcc agtctatgtc atcaactaca agggtgagga ggtctgtctg
    39481 gctcaggctc ctgttggctc cgctccagca gcccagttta tggattggtt gattggctat
    39541 ggtgtggagc agattatctc tactgggacc tgtggtgtcc tagctgatat agaggaaaat
    39601 gcctttctag tccctgttcg cgctttgcga gatgagggag ccagttacca ctatgtggca
    39661 ccttgtcgtt atatggaaat gcagccagag gctattgctg ctattgagga agttttggaa
    39721 gacagaggga ttccttatga agaagtcatg acctggacga cagacggttt ttaccgagaa
    39781 acggctgaaa aggtggctta tcgtaaggaa gaaggctgtg ctgttgtgga gatggagtgt
    39841 tctgctcttg cggcagtagc tcaattgcgt ggggttctct ggggtgaatt gttgttcaca
    39901 gcagattctc tagcggactt ggaccagtac gacagtcgtg actggggctc ggaagctttt
    39961 aataaggcgc tagaactgag tttagcaagt gttcaccacc tttagttgta caggcaaagg
    40021 atttgtttta tcataaaatg tctagctcat acttttcaaa aatatgttta aacgaggtca
    40081 ccttcctctt gtcctaggca tgttgaggtt gggaaaaatc tttaaaatca gaaaaacgta
    40141 tcatatcagg tgatgaaaat tttgatacta tgcgttttat gttggtaaga tttagagtga
    40201 gatgaaatga tactcttcga aaatcttttc aaaccaggtc agcttcacct tgccgtagat
    40261 atgttactga cttcgtcagt tctatctgca acctcaaaac agtgttttga gctgacttcg
    40321 tcagttctat ccacaacctc aaaacagtgt tttgagcaac ctgtgactag ctttctaatc
    40381 gatgccttga ttttcattgc ctataatcaa aaagagaaat tttctcctga aaagcatata
    40441 gagtagctgg cgttaaaagc tcctgtcttg cttttttgac ctatagtcac atctatcaag
    40501 tattgttctt gcctaagcta tcaataaaaa ggtggcattt tttaggcttg gtgttagtga
    40561 attttgcctt atcctatcta agtcatttcg agctttttat ggtacaatgg aaacatgtta
    40621 ttcaaattat ctaaggaaaa aatagagcta ggcttatctc gtttatcgcc agcccgtcgt
    40681 atttttttga gttttgcctt ggtcatttta ctaggctctc ttcttttgag cttgcccttt
    40741 gtccaagttg aaagctcacg agcgacttat tttgatcatc ttttcactgc tgtctctgca
    40801 gtctgtgtga caggtctctc aacccttcca gtagctcaca cctataatat ctggggccaa
    40861 ataatctgtt tgctcttgat tcagatcggt ggtctagggc tcatgacttt tattggggtt
    40921 ttctatatcc agagcaagca aaagcttagt cttcgtagcc gtgcaactat tcaggatagt
    40981 tttagttatg gagaaactcg atctttgaga aagtttgtct attctatttt tctcacgacc
    41041 tttttggttg agagcttggg agctattttg cttagttttc gccttattcc tcaacttggc
    41101 tggggacgtg gtctttttag ttccattttt ctagcgatct cagccttctg taatgccggt
    41161 tttgataatt tagggagcac cagtttattt gcttttcaga ccgatttact ggtcaatctg
    41221 gtgattgcag gcttgattat tacaggcggc cttggtttta tggtctggtt tgatttggct
    41281 ggtcatgtag gaagaaagaa aaaaggacgt ctgcactttc atacgaagct tgtactatta
    41341 ttgactatag gtttgttgtt atttggaaca gcaactactc tctttcttga gtggaacaat
    41401 gctggaacga ttggcaatct ccctgttgcc gataaggttt tagttagctt ttttcaaaca
    41461 gtgacgatgc gaacagctgg cttttctacg atagattata ctcaggctca tcctgtgact
    41521 cttttgattt atatcttaca gatgtttcta ggtggggcac ctggaggaac agctggggga
    41581 ctcaagatta cgacattttt tgtcctcttg gtctttgcac gaagtgagct tctaggcttg
    41641 cctcatgcca atgttgcgag acgaacgatc gcgccgcgaa cggttcaaaa atcctttagt
    41701 gtctttatta tctttttgat gagcttcttg ataggattga ttctgctagg gataacagcc
    41761 aaaggcaatc ctccctttat ccacctcgta tttgaaacca tttcagctct tagtacagtt
    41821 ggtgtaacgg caaatctgac tcctgacctt gggaaattgg ctctcagtgt tatcatgcca
    41881 cttatgttta tgggacgaat tggtcccttg accttgtttg ttagcttggc agattaccat
    41941 ccagaaaaga aagatatgat tcactatatg aaagcagata ttagtattgg ttaagaaagg
    42001 aaagagcatg tcagatcgta cgattggaat tttgggcttg ggaatttttg ggagcagtgt
    42061 cctagctgcc ctagccaagc aggatatgaa tattatcgct attgatgacc acgcagagcg
    42121 catcaatcag tttgagccag ttttggcgcg tggagtgatt ggtgacatca cagatgaaga
    42181 attattgaga tcagcaggga ttgatacctg cgataccgtt gtagtcgcga caggtgaaaa
    42241 tctggagtcg agtgtgcttg cggttatgca ctgtaagagt ttgggggtac cgactgttat
    42301 tgctaaggtc aaaagtcaga ccgctaagaa agtgctagaa aagattggag ctgactcggt
    42361 tatctcgcca gagtatgaaa tggggcagtc tctagcacag accattcttt tccataatag
    42421 tgttgatgtc tttcagttgg ataaaaatgt gtctatcgtg gagatgaaaa ttcctcagtc
    42481 ttgggcaggt caaagtctga gtaaattaga cctccgtggc aaatacaatc tgaatatttt
    42541 gggtttccga gagcaggaaa attccccatt ggatgttgaa tttggaccag atgacctctt
    42601 gaaagcagat acctatattt tggcagtcat caacaaccag tatttggata ccctagtagc
    42661 attgaattcg taaagaggga tgacccctct tttttgatgc ctaagatggc aaatagagac
    42721 agaagcccct tgtcttctag taaaagttct tcaaaggctg gactttatgg taaaatagaa
    42781 agaagtgaca agagagagta atactcaatg aaaatcaaag atcaaactag gaaactagct
    42841 acgggctgct caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaacatc
    42901 tatacggcaa ggcgacgttg acgcggtttg aagagatttt cgaagagtat aagaaaaaat
    42961 cagtccccta aaggagtaga ttatgaagtt attgtctatc gcaatttcta gctataatgc
    43021 agcagcctat cttcattact gtgtggagtc gctagtgatt ggtggtgagc aagttgggat
    43081 tttgattatc aatgacgggt ctcaggatca gactcaggaa atcgctgagt gtttagctag
    43141 caagtatcct aatatcgtta gagccatcta tcaggaaaat aaatgccatg gcggtgcggt
    43201 caatcgtggc ttggtagagg cttctgggcg ctattttaaa gtagttgaca gtgatgactg
    43261 ggtggatcct cgtgcctact tgaaaattct tgaaaccttg caggaacttg agagcaaagg
    43321 tcaagaggtg gatgtctttg tgaccaattt tgtctatgaa aaggaagggc agtctcgtaa
    43381 gaagagtatg agttacgatt cagtcttgcc tgttcggcag atttttggct gggaccaggt
    43441 cggaaatttc tccaaaggcc agtataccat gatgcactcg ctgatttatc ggacagattt
    43501 gttgcgtgct agccagttct aactgcctga acatactttt tatgtcgata atctctttgt
    43561 ctttacgccc cttcagcagg tcaagaccat gtactatctg cctgtcgatt tctatcgtta
    43621 tttgattggg cgtgaggacc agtctgtcaa tgagcaagtg atgattaagt gcattgacca
    43681 gcaactcaag gtcaatcgac tcttgataga ccaacttgat ttgtcccaag tgagtcatcc
    43741 caaaatgcga gaatatctgc tgaatcatat tgaactcacg acggtgattt ccagtaccct
    43801 gctcaaccga tctggaacag cggagcatct ggcaaaaaaa cgccaattgt ggacctatat
    43861 tcagcagaaa aatccagaag tctttcaggc tattcgtaag accatgttga gccgtttgac
    43921 caaacattct gtcttgccag atcgcaaact gtccaatgtc gtctatcaaa tcaccaaatc
    43981 tgtttatgga tttaattaat ataagtgttt tataagaggg atttaagaaa aattttaact
    44041 ttttcttagt cctttttaat ttcaggagat tatactagag tcatcaaata aagaaagact
    44101 ctaaggagaa tcctatgaaa ttcaatccaa atcaaagata tactcgttgg tctattcgcc
    44161 gtctcagtgt cggtgttgcc tcagttgttg tggctagtgg cttctttgtc ctagttggtc
    44221 agccaagttc tgtacgtgcc gatgggctca atccaacccc aggtcaagtc ttacctgaag
    44281 agacatcggg aacgaaagag ggtgacttat cagaaaaacc aggagacacc gttctcactc
    44341 aagcgaaacc tgagggcgtt actggaaata cgaattcact tccgacacct acagaaagaa
    44401 ctgaagtgag cgaggaaaca agcccttcta gtctggatac actttttgaa aaagatgaag
    44461 aagctcaaaa aaatccagag ctaacagatg tcttaaaaga aactgtagat acagctgatg
    44521 tggatgggac acaagcaagt ccagcagaaa ctactcctga acaagtaaaa ggtggagtga
    44581 aagaaaatac aaaagacagc atcgatgttc ctgctgctta tcttgaaaaa gctgaaggga
    44641 aaggtccttt cactgccggt gtaaaccaag taattcctta tgaactattc gctggtgatg
    44701 gtatgttaac tcgtctatta ctaaaagctt cggataatgc tccttggtct gacaatggta
    44761 ctgctaaaaa tcctgcttta cctcctcttg aaggattaac aaaagggaaa tacttctatg
    44821 aagtagactt aaatggcaat actgttggta aacaaggtca agctttaatt gatcaacttc
    44881 gcgctaatgg tactcaaact tataaagcta ctgttaaagt ttacggaaat aaagacggta
    44941 aagctgactt gactaatcta gttgctacta aaaatgtaga catcaacatc aatggattag
    45001 tt
//
LOCUS       DAVMAH010000011        44130 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVMAH010000011 DAVMAH010000000
VERSION     DAVMAH010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44130
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.011"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            129..1622
                     /locus_tag="VYO94_000543"
     CDS             129..1622
                     /locus_tag="VYO94_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1759227.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..2177
                     /locus_tag="VYO94_000544"
     CDS             1635..2177
                     /locus_tag="VYO94_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1759228.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLLVKSRYSEEVVA"
     gene            2174..3235
                     /locus_tag="VYO94_000545"
     CDS             2174..3235
                     /locus_tag="VYO94_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1759229.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRVQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSSGKFLDKHDRVFEGYPAYG
                     GNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWISDNAIYIKEFKNSDFNLVF
                     LLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQNEFADFVALVDKSQLAIQ
                     KSLEELETLKKSLMQEYFG"
     gene            3295..3531
                     /locus_tag="VYO94_000546"
     CDS             3295..3531
                     /locus_tag="VYO94_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV1759230.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            3528..3941
                     /locus_tag="VYO94_000547"
     CDS             3528..3941
                     /locus_tag="VYO94_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV1759231.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            4059..5024
                     /locus_tag="VYO94_000548"
     CDS             4059..5024
                     /locus_tag="VYO94_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1759232.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            5047..5628
                     /locus_tag="VYO94_000549"
     CDS             5047..5628
                     /locus_tag="VYO94_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1759233.1"
                     /translation="MFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTK
                     NVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRI
                     NSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQ
                     NEFADFVVQVDKSQFACEIAIKVWRNSLKFSII"
     gene            5658..9008
                     /locus_tag="VYO94_000550"
     CDS             5658..9008
                     /locus_tag="VYO94_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1759234.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAEIRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSLLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(9514..9984)
                     /locus_tag="VYO94_000551"
     CDS             complement(9514..9984)
                     /locus_tag="VYO94_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1759235.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(10001..12274)
                     /locus_tag="VYO94_000552"
     CDS             complement(10001..12274)
                     /locus_tag="VYO94_000552"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV1759236.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            12621..15722
                     /locus_tag="VYO94_000553"
     CDS             12621..15722
                     /locus_tag="VYO94_000553"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV1759237.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVSYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            15805..16812
                     /gene="pfkA"
                     /locus_tag="VYO94_000554"
     CDS             15805..16812
                     /gene="pfkA"
                     /locus_tag="VYO94_000554"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV1759238.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            16871..18376
                     /gene="pyk"
                     /locus_tag="VYO94_000555"
     CDS             16871..18376
                     /gene="pyk"
                     /locus_tag="VYO94_000555"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV1759239.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(19111..19336)
                     /locus_tag="VYO94_000556"
                     /pseudo
     CDS             complement(19111..19336)
                     /locus_tag="VYO94_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            20184..21056
                     /locus_tag="VYO94_000557"
     CDS             20184..21056
                     /locus_tag="VYO94_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV1759240.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(21202..21546)
                     /locus_tag="VYO94_000558"
                     /pseudo
     CDS             complement(21202..21546)
                     /locus_tag="VYO94_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            21689..22000
                     /locus_tag="VYO94_000559"
     CDS             21689..22000
                     /locus_tag="VYO94_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759241.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKKREELRQIITTIFEQKMNKHSI
                     K"
     gene            22004..22720
                     /locus_tag="VYO94_000560"
     CDS             22004..22720
                     /locus_tag="VYO94_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1759242.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(22849..23664)
                     /locus_tag="VYO94_000561"
     CDS             complement(22849..23664)
                     /locus_tag="VYO94_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV1759243.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTNLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(23661..24566)
                     /locus_tag="VYO94_000562"
     CDS             complement(23661..24566)
                     /locus_tag="VYO94_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV1759244.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            24956..26272
                     /locus_tag="VYO94_000563"
     CDS             24956..26272
                     /locus_tag="VYO94_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEV1759245.1"
                     /translation="MERQTLKDIEVIIVNQSTEEIASISQQMNLSFNIKIIDENSFAE
                     LSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGHFSDLVDGVFYFYPWGD
                     NWLTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQFDINNLIWRLYIH
                     SKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLENYDIERAKKQYIQ
                     ELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTIISNNCVGGLIYRQ
                     LGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPSWTHEVYPLGHLGDI
                     DIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNKMDNLPYSNKLIL
                     VNRPYKNLKSQCVIPGQEHLPELAIMSDPLNTFDIMAWLKKGGNAL"
     gene            26374..28503
                     /locus_tag="VYO94_000564"
     CDS             26374..28503
                     /locus_tag="VYO94_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV1759246.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKSADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            28490..28939
                     /locus_tag="VYO94_000565"
     CDS             28490..28939
                     /locus_tag="VYO94_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV1759247.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            28998..29270
                     /locus_tag="VYO94_000566"
     CDS             28998..29270
                     /locus_tag="VYO94_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1759248.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(29624..29815)
                     /locus_tag="VYO94_000567"
     CDS             complement(29624..29815)
                     /locus_tag="VYO94_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759249.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            30243..31001
                     /locus_tag="VYO94_000568"
     CDS             30243..31001
                     /locus_tag="VYO94_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759250.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            31003..32991
                     /locus_tag="VYO94_000569"
     CDS             31003..32991
                     /locus_tag="VYO94_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1759251.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(33034..33678)
                     /locus_tag="VYO94_000570"
     CDS             complement(33034..33678)
                     /locus_tag="VYO94_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV1759252.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFTAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLGQLFSI"
     gene            complement(33704..34579)
                     /locus_tag="VYO94_000571"
     CDS             complement(33704..34579)
                     /locus_tag="VYO94_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1759253.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNCKRSVRKSSVTKELKEKILHYHNQ
                     KFSPDKKQASINFKPAGQSIEQRPEAINFRLENGHYEIDTVLLTRAKNYCLLVLTDRK
                     SRHQIIRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHP
                     YASWERGTNENHNRLIHRWLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWM
                     ANLNLKFSVRNKSRN"
     gene            35286..36761
                     /locus_tag="VYO94_000572"
     CDS             35286..36761
                     /locus_tag="VYO94_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV1759254.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEIAHEAGMMVLVDEAHGAHLHFTDKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSILLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(36727..37442)
                     /locus_tag="VYO94_000573"
                     /pseudo
     CDS             complement(36727..37442)
                     /locus_tag="VYO94_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            37529..37666
                     /locus_tag="VYO94_000574"
     CDS             37529..37666
                     /locus_tag="VYO94_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759255.1"
                     /translation="MRYQTHYQLKQKLWLDPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            37697..38557
                     /gene="speE"
                     /locus_tag="VYO94_000575"
     CDS             37697..38557
                     /gene="speE"
                     /locus_tag="VYO94_000575"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV1759256.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            38554..39813
                     /locus_tag="VYO94_000576"
     CDS             38554..39813
                     /locus_tag="VYO94_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV1759257.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            39813..40940
                     /gene="nspC"
                     /locus_tag="VYO94_000577"
     CDS             39813..40940
                     /gene="nspC"
                     /locus_tag="VYO94_000577"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV1759258.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            40937..42022
                     /gene="aguA"
                     /locus_tag="VYO94_000578"
     CDS             40937..42022
                     /gene="aguA"
                     /locus_tag="VYO94_000578"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV1759259.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            42032..42907
                     /gene="aguB"
                     /locus_tag="VYO94_000579"
     CDS             42032..42907
                     /gene="aguB"
                     /locus_tag="VYO94_000579"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV1759260.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(43088..43897)
                     /locus_tag="VYO94_000580"
     CDS             complement(43088..43897)
                     /locus_tag="VYO94_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1759261.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
BASE COUNT        13759 a         7732 c         9302 g        13337 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga tcagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcca
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaggtcatc ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attagaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt cttatctcta aaaaaaggca
     1681 agaaagccac tgtacttgct gaacaaacaa ctctaagcca acgttatatt caaatagatg
     1741 atttaagaaa taataataat ttaaaattca ctgaaagttt aaatatgact gaagcactcc
     1801 cagatgatat tctgatagca tgggatggag ctaatgcagg aacagttggt tatggattat
     1861 cgggagctgt tggtagtaca attacggtct taaaaaagaa tgagcgatac aaagaaaaaa
     1921 ttatatcaga ttacttggga gtctttttgg aaagtaaatc gcagtattta cgagaacatt
     1981 caacaggtgc aacaattcct catttaaaca agaatatatt acttgattta caattagaat
     2041 tgctaggtat cgaagaacaa gagaacatta tctgtattct taatacgatt aaagggctta
     2101 ttactaaaag aaaattgcag ttagatgaac taaacttgct cgtcaaatcc cgatattccg
     2161 aggaggtggt tgcatgaaga aagtgaaatt agggcaagtg gctactttta tcaatggcta
     2221 tgcttttaaa cctcaagatt ggtcatctga agggaaagag attatcagag tacagaatct
     2281 gactaaaact tcaaaaggga taaattatta ttcgggtacg attgataaaa aatacattgt
     2341 tgaagctggt gatattctta tttcgtggtc gggtacatta ggggtttttc agtggtgtgg
     2401 aagatccgca gtattaaatc agcacatttt taaagtggtt tttgataaga tagatataga
     2461 taaatcgtat tttaaatatg ttgttgaaaa aggtttacaa gatgctgtaa aacatactca
     2521 tggttccaca atgaaacatt taactaaaaa atattttgat aatattatag ttccatatac
     2581 aaatttggga gagcaacaaa gaattgcaag tgagctggat ttgttaagca agctgatttt
     2641 aaggagacaa gaacaacttg aagagcttaa tctacttgta aaatcccgat ttaacgagat
     2701 gtttggggat cctttaaata ataacaagaa atttgcagta aaaacgggac aacagtgttt
     2761 taaattttca agtggaaaat ttcttgataa acatgataga gtttttgaag gttatcctgc
     2821 ctatggtgga aatggcattg cttggaaaag tcgaaaatat ttaattgata atcctactat
     2881 catcattggt cgtgtaggtg catattgtgg taatgtaaga actacccacg gtaaggtatg
     2941 gataagtgac aatgctatat atataaaaga atttaagaat tccgatttca atcttgtatt
     3001 tttattagaa ttaatgaaag taattgattt tagtaaattt gctgatttct caggtcaacc
     3061 aaagataact caaaaaccat tagaaaatca gaaatatatc ctcccccctc tagccctcca
     3121 aaatgagttc gcagactttg tagccctggt cgacaaatca caattggcaa tccaaaaatc
     3181 tctggaagaa cttgaaactt tgaagaaatc tctgatgcag gagtattttg gctgatattc
     3241 tgccattgta attacggtaa tgatttgtta taatacttca aaggaggaaa tcagatggta
     3301 gtaaaaacaa gaaaacaagg aaattcaatc accattacga ttccaagtga atttaatatt
     3361 ccaagtggtg ttaaatacga agcgaaattg ttaccaagtg gtgagattat ctttactcct
     3421 gaagaattgg ggcagcaggt ttcttatgta tctgatgatg cctttgactt aaatttagat
     3481 aaaatatttg acgaatacga cgatgttttc aaagctttgg tggaaaaatg acaatctatc
     3541 tgacagaaaa gcaaattgaa aaaataaatg ctttagcaat tcaacggtat tctccaaatg
     3601 agaaaattca aacagttagt tcttctgcct taaatatgat tgtgaactta ccagaacaat
     3661 ttgtctttgg gaagtctctt tatccaacaa tttttgataa agcaacgata ctatttgtcc
     3721 aattgataaa gaagcatgtt tttgctaatg ctaataaaag aactgctttc ttcgttttgg
     3781 tcaaattttt acaattaaac ggctatcgtt tttctgtaac ggtagaagaa gcagtaaaaa
     3841 tgtgtgtaac catcgcagta gaagctttaa ctgatgaaaa aatgacaagc tactccaaat
     3901 gggtttctga acattctgtt agagaaaagg tcaaaaagta acctagtatg ctggatttga
     3961 atgagcacaa gaaaataaat gaacagacaa tattagaatt ctgtaatgca gaaactgata
     4021 ttgtctcttt ttattgatga ataagaaagt gagaaattat ggaatcaaaa gttacaatta
     4081 tcatgcaaga aatgttacct cttttaaata atgaacaatt actagcgttg agagagagtt
     4141 tagaacatca tctagtagac ggaaaaaagc agcagaagta ttcgaataat aacctgttgc
     4201 aactatttat taccgccaag caggtagagg gctgtagctc aaaaacaatt cgttattacc
     4261 agaggacgat tgaaaacttg tttaatgcta ttaaagagtc tgtgacacaa ctcacaacag
     4321 atgatttaag gagttattta gcaaattacc agtctgaaaa ggattgtagt aaggcaaatt
     4381 tagacaatat taggcgtata ttgtcttctt tttttgcttg gcttgagcaa gaggaatata
     4441 tcattaaaaa tcccattcga cggataaaga aaattaagac tgagcaaaat gtgaaggaaa
     4501 cttatactga tgaacatttg gaaattatgc gtgataactg tgaaaatttg agagatttgg
     4561 caataataga cctactagca tcgacaggta tgcgtgtagg ggagcttgta cagttgaatc
     4621 gttcagatat tgattttgaa aacagagagt gtgttgtctt tggtaaagga aagaaggaga
     4681 gaccagtata ttttgacgct cggacgaaaa ttcatttaag aaattatctt aacgacagaa
     4741 aagatagtca ccctgctctt tttgtaacgc tagttggaaa agcccagaga cttggaattg
     4801 ctggtgtaga gattcgctta agaaagttag gagacaaact cggcatacaa aaggttcacc
     4861 cacataagtt cagaagaact ttagcgacta aggcaattga taaaggtatg cctatcgaac
     4921 aagtccaaaa actgctaggt catagcaaga ttgacacaac cctggcctat gccatggtca
     4981 atcaaaataa tgtcaagcat tcacaccaaa aattcatctc ttaaaagcaa atcccgattt
     5041 aacgagatgt ttggggaaaa taaaatattt gaaagcattg ataacttatt tgatattata
     5101 gatggtgata ggggcaaaaa ttatcctaaa tcagatgagt tgtttagtga ggagtactgt
     5161 ttatttttaa atacaaagaa tgttactaaa aacggatttt cattcgatac aaagcaattt
     5221 atcactaaaa caaaggataa attacttcga aaaggcaaac ttgagcgtta tgatatagtc
     5281 ttgacaacaa gaggtactgt tggaaatgta gcgtactacg atgaattaat aaaatataaa
     5341 catttacgta taaattcagg tatggtaata ttacgtccca agacaccaaa tctaaatcag
     5401 aaatttatta tccatgtttt aaggaataat aattatagtc gagtgatatc aggaagtgct
     5461 cagcctcagt taccaattac aaaattaaaa aaaatacttc tccccctccc cccactagcc
     5521 ctccaaaatg agttcgcaga ctttgtagtc caggtcgaca aatcacaatt tgcttgtgag
     5581 atagctataa aagtgtggag aaatagcttg aaatttagta taatatagct aaactatttg
     5641 tttaaagtga gaaaaaaatg ggaaatttta gctttctttt aaaaaatgac gaatatgaat
     5701 ctttttcaaa accttgcatt gaagctgaga atatgattgc tacatcaact gtggctactg
     5761 cctttatggc gcgtcgtgct ttagagcagg ctgtccattg gatatatagt cacgattcat
     5821 atttagaagc tccctatcgt gctactctat cttctttagt atgggatgat gattttaggg
     5881 atatcgtaga ttctgaactc cacaagcaga tagttctgtt gattcggtgg ggaaaccatg
     5941 ctgctcatgg tggtgaaatt aaggaacgag aagcgatttt agctttgcat catttgtatc
     6001 agtttgttaa ttttatcgat tattgttaca gcaatgagtt tgtggagcgt tattttgatg
     6061 agaagtgctt accactttca gcaaacatca aataccgaga aactccacaa tctatgataa
     6121 agttacaaga cagtttacca gaactgcctg attttcatga acagatggct gctcagtccg
     6181 tagaagttca agagacttat actgaaaaac gtgagactgc agcgcaacgg caagatgtgc
     6241 ctttccatat tgatcaatta tctgaggcag agataagaaa gctctttatt gatatcgatc
     6301 tccgtttagc aggatggata tttgaagaaa actgtcgtgt tgagatagcc gttgatggtc
     6361 tcaagcacgg ttcaggaatt ggttactgtg actatgtact ttatggtaaa aatgggaaaa
     6421 ttttagcgat tgtagaggct aaaaaagcct ctgtcaatcc agaagtaggg gaagtacagg
     6481 tcaaagaata tgctgaagct cttgagaaac atatcggcta tcagccaatt tgctttatta
     6541 caaatggctt gaagcactat atacttgatg gtccgaaccg ccgccagatt gcaggctttt
     6601 actctcaaga agaattgcaa ttagtgatgg atagacgtca tcttcaaaaa ccacttgagg
     6661 atatttctag taaaattagg gacgatattt ccgggcgtca ctaccaaaaa catgccattg
     6721 caagcgtttg tgaagctttc tctaatcatc gtagacaggc acttttggtt atggcaactg
     6781 gggctgggaa aactcgtaca gcagtttctc tagttgatat cttatcacgt cataactggg
     6841 taaaaaacgt tctcttctta gccgatagaa cttccttggt taagcaagcc tatgattcgt
     6901 ttagaaaatt actcccagat ctttccgttt gtaacttctt agaagataaa gaaggagctc
     6961 aatcaagtcg catggtcttt tcaacttatc cgaccatgat tggagcgatt agtggtcaag
     7021 aagaagtaaa tcaacgccct ttcactgttg ggcattttga ccttatcata attgacgaat
     7081 ctcaccgttc tatttatcag aaatacaagt ccatttttga ttattttgat gcaagaattg
     7141 taggcttaac agctactccg cgtcaagatt tagataaaaa cacctatgga ttctttaatt
     7201 tggagaatgg ggttccaaca tatgcatatg atttggaaga ggctgttaaa gacggatatt
     7261 tagtagccta tcattctatc gaaaccaaac tgaaactacc tacggatggt ctacattatg
     7321 atgatttgtc cgaagaagaa aaggaacatt ttgatagcaa atttgaagac gatagctgtg
     7381 aaaaagatat tgatgggagt gtatttaatt cctttgtttt caataaaagt acagtagaaa
     7441 ttgttttaaa tgaactcatg acaagaggaa ttcagacagc ctcgggtgat gaaattggta
     7501 aaactattat ttttgctaaa aatcatgatc atgcggaata tatcagaggt atttttaaca
     7561 accgctatcc tgaaaaaggg agcgactatg ctcaggtgat tgattatagt attaagcatt
     7621 atcagacctt gattgatgat tttaaaatta aggagaagta tcctcaaatt gcgatttctg
     7681 tcgatatgtt agatacaggt attgatgtac cagaggttgt taatttagtc ttcttcaaga
     7741 aagtacgctc taaaactaag ttttggcaga tgattggtcg aggaacccgt ctatgtaaag
     7801 atttatttgg acctgagcag gataaggaaa acttcttggt atttgattat ggggacaatt
     7861 ttgattattt tcgtgcagat ccaagagatg gagagggtcg tcacattgtt tcgttgactc
     7921 agcgtttatt taatatcaaa gtggacttga ttcgagaact tcagggactc caataccaag
     7981 aagatcagtt tgcgagagca taccgtcagc agcttgtctc ggaacttcaa ggtcgtatag
     8041 agagcttaaa tgagttggac ttcagggttc gtatggtttt agatacagtt tatagctata
     8101 ggaaattgga aagttggcag aatctaactg ctgttacaag tgaaaccatt caaaaaaatc
     8161 tctctctgct tttatttgat gaagataaag aagatgagat ggcgaggaga tttgatttgt
     8221 ggttgcttca tattcagttg gggcaactga cagctaaatc ttccactgtt catatttccc
     8281 aagtgatgaa gacggctaga gctctttctg ctattggcaa tatcccgcag gtttttgagc
     8341 aggctgaaat tatcaggaaa gtacaggagc ctgaattttg gaaagaagtt aacttgtctg
     8401 atttggaaaa aattcgtctt gctattcgag atttattaca gtttttggat aaaacagacc
     8461 gtaaacccta ctatgttaac tttgaagatc gtatactctc cactgttcac gagaccacag
     8521 catttttgca ggtcaacgat cttcggtctt acaatgaaaa agttgagcat tatttgaaaa
     8581 ctcatctgga tgaggagtcc atttctaagc tataccataa taaaaagttg acatctgatg
     8641 atatgcttgc acttgaaaaa ttgctttggg aaaaattagg tagtaaagca gactaccaaa
     8701 gtcattatga aaataaggca attccgagat tggttcgtga gattattggc ttagatagag
     8761 agtctgccaa tcgtattttt tctaaatttt tgtcggatga gaatcttaat gccaggcaga
     8821 tttcatttgt aaaattgatt gtagactaca ttgtagaaaa tggtttttta gagacgaaag
     8881 tgttaacgca agagccgttt aaatcttatg gttctgttca actactcttc caacaccaac
     8941 taccagtact tcgtaatatt gttcaaatca ttgaacttat caataatcga gctggagaag
     9001 cggcttaaat tctaaagtga ttgccatgct gagactcatt taaaattaaa aagagtagaa
     9061 atttatgcta tatatgagaa gttttattag gaagaatgtc atcgttttcc tagaatacag
     9121 tatcagttgt taagtggttg ataaatttca aagtagatac ttgtaccacg atgtttgttg
     9181 atcgagttat taacaaaaga gctactttga ttttaaagaa atagaaaaca aaaagccgag
     9241 caagaattca attgcaggag aaaatgaaat aatactcaat gaaaatcaaa gagcaaacta
     9301 ggaaactagc tgcaggctgc tcaaaacact gttttgaggt tgtagatgga agctgacgcg
     9361 gattgaagag attttcgaag agtataaatc ttcctaggat aaagcaaaac gcatagtatc
     9421 aagggttttc aacacttgat actatgcgtt ttctgatgtt aaagactttc taccaggttt
     9481 tttaaaagca taattgttag ttgtagtcat ttattattct tcaaagaaaa atggtggggc
     9541 gaattttttc agttcttcaa agcacttttg agcagtatct gcatcttcac agatgataag
     9601 acagacatca ttaccacaaa gggtagcgat agcgtcaggg aagctcaaag tatcaatgat
     9661 agaaccaaag gattgagcca gtccaggaag ggtttttagt aggacttggt gttgaactgg
     9721 gcgcatccag acaagggcgt cttccatgta gagttcgaga cgtttttccc attttgagat
     9781 ggaaccattg ttaagaacat aataagcgct atcttcttcg cggacttttg ataggttcat
     9841 atttttgatg tcgcgtgaga gggttgcctg ggttacttga atgtcgttct cagcaagaag
     9901 ggcttgcaac tcagcctgtg tatgaatctt gttttttgtg ataagagcgc gtataagttg
     9961 gtggcggtgt tctgatttat tcataataat gtaactcctt ttagcaaggt aaggtaagca
    10021 tggactgagc gaggtcgaca gtcaagtggt agtctgtatt gtcacggatg gtgatttcaa
    10081 agtcagtagt atagaggact aaacggagag tgtctccttc ttttagcttg taaatagttg
    10141 gctgcagttc aaattgaacg tccatccatt catctgcagt aatatcctct actaacagta
    10201 aatcatttct attttgtaaa ttaaggtaac cttttgtcac gactcgttgt gcctctggtc
    10261 taaatggcaa ttcacagaga ttttccaaca tgtgatagcg accgttgtca atggttctag
    10321 cacttaaaat agctggataa ggttgtaggt atttcttttg cccaaattct agcagttggg
    10381 cagataagag ccccttgttt gtactggatt tgatacgaag attgagctga gcgcgaccgt
    10441 ttaggtggag atctttagtc acaggaaggt taatagtaat ctgattggct ttcccttgat
    10501 agagctctgt attgaaggtt tggtatgtct taccatagcg ctcaaaatcc ttatctgggt
    10561 actggttttg aatagcttgc tcttcttgac caagtgagaa ggtttcacag ttttcttgcc
    10621 caccgaagtt atcaagtgat aaccaagtct gtggagctgt attgtcctgc cagataacag
    10681 taggaagttg aaagtctgtt tcctgtccta gtaatttctt ggtcaataag gcatttatgg
    10741 actcacggaa gtcaattgat tgccaattgt tcatgtaaac atgggcacca ttatggaaaa
    10801 agagatgctt gtgtatatga gtaggaagag catggaacat ctggtaaaca tgaagtggtt
    10861 tgacattcca atcctgagaa ccatgagtaa agacaacctc tgcctttact ttatgggcat
    10921 tgagcagata attgcggtca tgccaaaact gattgtagtc cccagttttt cggtctagct
    10981 gagctttcac tttttctaag tcagcttggt gagcttcatt gccacggata tagtcgccag
    11041 ctaagagatt acgagaatag gttaactcag caagggagtc aaagtcctca cctggataac
    11101 cacctgggct agtcaccaga ccgttttcac ggtagtagtt gtaccatgat gaaattcctg
    11161 cctcggcaat gataacttct aaaccatcga ctcctgtagt cgcaagacca ttggacatgg
    11221 tacctagata ggaaagtcct gttgtagcaa cttttccgtt tgaccaatca gccttgactt
    11281 gacgctggcg cgtgtgatca gtaaaggcac ggcaacggcc gttaagccaa tcgatgacat
    11341 ttttataagc ctcgatttgc tggtagtctc cattagtcat gaaacctgtc gagtctttgg
    11401 taccaacacc tgagacatag agattggcaa agcctctcgg aaggaagtag tcgtttagtg
    11461 tatagctaga gttgatgtga gttagctttt cctcagcctc tgctataagc tcagctttac
    11521 cttggggttg gacgagattt agttgaggtt tctctagctc aatcttgtga ggaagtttaa
    11581 cctcaagctc gccctccatc ttgtagagag ccttgtcact agccttgtca ttggttccct
    11641 gatgataagg gctggctgtc atgatggcag ggatttttcc atcaaaacga gggcgaataa
    11701 tgctaacctt tactaggtct gatagccctt tttggtcagt atcgacacga gactcaacgt
    11761 aaacgacttc acgaatgaca tcctggttag aaaaagtagc caaactcttg ccgttaaagt
    11821 agtggtagtc attatcctcc ggaataagac catcactaac aagttggtcg ataagagtat
    11881 ttcctttttt ggtgcgagta ttgagtaact gatagagatt ttcaatcaag tcaccatata
    11941 taatgggaaa tccagtttct ttacgaaaaa cgtcactatc ttcgaagtca accaaataag
    12001 aaaagcctaa aagttgaaaa gcaacagtat aaaaaatatc tgctgtcagt tcatcttctg
    12061 attgaaaaaa tgtcagcagg tctgtttttt tatcagctgc taggatagaa agtgggtagt
    12121 tggtgtcttg ataagtgaaa aagaaacgac gtaaaaaggt ttcaagtgag tctttgtgat
    12181 tggctgtatt ttgtaaatca aagccacatt tttttagttc agataagaca ttttcttttg
    12241 gaaaattgat ataactatat tgattaaaac gcatagaacc tccatataga atgacagtta
    12301 aggttattat atcaaaaaaa aagcagaaag ggaattgtta acttcaaaag gaaataatcc
    12361 aataaaaatg aataaagtac taaattcaat atagagaaca gagtaacaat aagaataaat
    12421 agatagggta taaaagttct aggagattta tattatatgc tttctatttt tatatacaat
    12481 atagtataaa tataaaaatg atgacaaaaa tacaaatgaa tagaaaataa attagtaagc
    12541 tgatgaaatt tttctcaaga gaagctattt ataggtgaaa atggtataat atagtgagaa
    12601 ggatagagga gaagtgtaaa ttgatcgcac aactagatac aaaaacagtc tatagtttta
    12661 tggaaagcgt catttcgatc gaaaagtatg tgagagcagc taaagaatac ggctacactc
    12721 atttggctat gatggatatt gacaatcttt atggcgcttt cgactttcta gagattacaa
    12781 aaaaatacgg cattcatcct ttgctagggc ttgaaatgac agtgtttgta gatgatcagg
    12841 aagtgaattt gcgcttttta gctctatcta gtgtgggcta tcagcagttg atgaagcttt
    12901 cgacagccaa gatgcagggg gagaaaactt ggtcagtcct gtcccagtac ctggaggata
    12961 tcgcggtcat tgtgtcttat tttgatagag ttgagtcgtt agaactaggc tgtgattact
    13021 atataggggt ttatccagaa acactagcaa gcgaatttca tcatcctatc ttacctcttt
    13081 atcgggtcaa cgcttttgaa agcagggata gagaagttct tcaagtttta acagcgatta
    13141 aagaaaatct accgctcaga gaagttccct tgcgttcgag acaagatgtc tttatatcag
    13201 caagttcttt agagaaacta ttccaagagc gttttccgca agctttggac aatttagaaa
    13261 agcttatttc aggcatttct tacgacttgg atactagtct gaaactgcct cgttttaatc
    13321 cagctagacc agcagtagag gagttgagag agcgtgctga actggggctt gttcagaagg
    13381 ggttgactag taaagaatat caagatagac tagaccaaga attgtctgtt attcatgata
    13441 tgggctttga tgattatttc ttggttgttt gggatttgtt gcgttttgga cgatcgaatg
    13501 gctattatat gggaatggga aggggttctg cagtaggcag tttggtttct tatgccttag
    13561 acatcacggg gattgaccca gtagagaaaa atctgatttt tgaacgcttt cttaatcgtg
    13621 aacgctatac catgcctgat attgatattg atatcccaga tatttatcgt ccagatttta
    13681 tcagatatgt tggtaataaa tatggtagta aacatgcggc acaaatcgtt actttttcaa
    13741 cctttggagc caagcaagct cttcgagatg tcttgaaacg ctttggtgtg ccagagtatg
    13801 aattatctgc aattactaag aaaatcagtt ttcgtgacaa tcttaagtcg gcctatgagg
    13861 gcaatctcca gtttcgtcag caaatcaata gtaagttaga ataccaaaaa gcttttgaga
    13921 ttgcttgcaa gatagagggc tatccaaggc aaacctctgt ccatgcggct ggtgttgtaa
    13981 ttagtgacca agatttaacc aactacattc ctctaaagta tggtgatgaa attccactga
    14041 ctcagtatga tgctcatgga gttgaggcta gcggactttt gaagatggac tttctgggac
    14101 tacgaaattt gacctttgtc cagaagatgc aagagttgct tgctgaaaca gaaggtattc
    14161 atctgaaaat tgaagaaatc gatttagaag acaaagaaac gttagcttta tttgcctctg
    14221 gtaatacaaa aggtatcttt caatttgagc aaccaggtgc cattcgtctg cttaagcgtg
    14281 tgcaaccagt ctgttttgaa gatgtcgtcg cgactacttc tctaaatcga ccaggtgcaa
    14341 gtgactacat caataatttt gtggcaagga agcatgggca ggaagaagtg actgttctag
    14401 attcagctct ggaggatatt ttggctccaa cttatggcat tatgctctat caggagcagg
    14461 ttatgcaggt tgctcagcga tttgctggat ttagtcttgg gaaggccgat attttgcgtc
    14521 gagctatggg taaaaaggat gcctctgcta tgcatgagat gagggcttcc tttattcaag
    14581 gctccataga agcaggccat actgcggaaa aagcagagca ggtttttgat gttatggaga
    14641 agtttgcagg ttatggattt aatagatctc atgcctacgc ctactcagcc ttggccttcc
    14701 agttggctta tttcaaaacg cattatccag ccatttttta tcaggtcatg ttaaattatt
    14761 ccaacagtga ttacttaata gatgcacttg aagcaggttt tgaagtagcc tctctatcca
    14821 tcaatactat tccctatcac gataaaattg ccaacaagtc tatctatata ggtttgaaat
    14881 cgattaaggg gctcagcaag gacttggcgc tttggattat tgaacataga ccttattcta
    14941 acattgaaga ttttatagct aaattacctg agaattatct gaaacttcct ctgctagaac
    15001 ctttggtaaa agttggtctt ttcgattcat ttgaaaaaaa tcgtcaaaaa gtatttaata
    15061 acttagctaa tctatttgaa tttgtgaaag agttgggaag tttgtttgga gatgctattt
    15121 atagttggca ggaatcggaa gattggacgg aacaagaaaa attttatatg gaacaagagc
    15181 ttttagggat aggtgtcagc aaacatccac tacaagctat tgcaagtaag gctatttacc
    15241 cgattacccc aatcggaaat ttgtcagaaa atagctatgc tattattttg gttgaagttc
    15301 agaaaataaa agtgattcgt accaaaaagg gtgaaaatat ggccttctta caggcagatg
    15361 atagtaagaa aaaattggat gtcactctct tttcagactt atatcgtcag gttggacagg
    15421 aaataaaaga gggagccttc tactatgtaa aaggaaaaat acaatcacgt gatggccgtc
    15481 tgcaaatgat tgcacaagaa ataagagaag cagttgctga acgcttttgg atacaggtga
    15541 aaaatcatga atcggatcaa gaaatttcac gcattttaga acaatttaaa ggcccaatcc
    15601 cagtcatcat ccggtatgaa gaggaacaga aaaccatcgt ttctccccat cattttgtag
    15661 ctaaatccaa tgaattagag gagaaattga atgaaatcgt tatgaaaacg atttatcgct
    15721 aaaaatacgg aaaatagaag aattttaaaa tcaaatgtga tataatcaag aagaatgtta
    15781 aaagaaaaag gagcataaac caatatgaaa cgtattgctg ttttgactag tggcggagac
    15841 gcacctggta tgaacgctgc catccgtgca gttgttcgtc aagcaatttc agaaggaatg
    15901 gaagtgtttg gtatctatga cggatatgct ggtatggttg ccggtgaaat tcatccccta
    15961 gatgcagctt cagtagggga catcatttct cgtggtggta cttttcttca ctcagctcgt
    16021 tatccagagt tcgctcaact tgaagggcaa cttaaaggga ttgagcaatt gaaaaaacac
    16081 ggaattgaag gtgtagttgt tatcggtggt gacggatctt accacggcgc tatgcgtttg
    16141 actgaacatg gcttcccagc tattggtctt ccaggtacaa tcgataacga tatcgttggt
    16201 actgacttta caatcggttt tgacacagcg gttactactg ccatggacgc tatcgataag
    16261 attcgtgata catcatcaag tcaccgtcgt acttttgtaa tcgaagttat gggacgtaac
    16321 gctggtgata tcgctctttg ggctggtatt gcaactggtg ctgatgaaat catcatccct
    16381 gaagcaggct tcaagatgga agatatcgta gcaagcatca aagctggtta tgaatgtggt
    16441 aaaaaacaca atatcatcgt cttagctgaa ggtgtgatgt cagcggctga atttggtcaa
    16501 aaacttaaag aagctggaga tacaagcgac cttcgtgtaa cagaacttgg acatattcaa
    16561 cgtggtggtt ctccaactgc gcgtgaccgt gttttggcgt cacgtatggg tgcacatgct
    16621 gttaaacttc ttaaagaagg tatcggtggt gttgcggttg gtattcgtaa cgaaaaaatg
    16681 gttgaaaatc caattcttgg tactgcagaa gaaggggcat tgtttagcct tactgcagaa
    16741 ggtaagattg tggttaacaa cccgcacaaa gccgatattg agctatctag cttgaataag
    16801 agcttgtcat aatttacaat ttagttaata agaccaaaaa ggtcatatat ataaaggagt
    16861 cacaaaaatc atgaacaaac gtgtaaagat cgttgcaact ttgggtcctg cggtagaaat
    16921 ccgtggtggt aaaaaattcg gtgaggacgg atactggggt gaaaaacttg atgttgaagc
    16981 ttcagctaaa aacattgcta aattgattga agctggtgct aacacattcc gattcaactt
    17041 ctcacacggc gaccaccaag aacaaggtga gcgtatggca actgttaaac ttgcggaaaa
    17101 aattgcaggt aaaaaagttg gtttccttct tgatacaaaa ggacctgaaa tccgtacaga
    17161 attgttcgaa ggtgaagcta aagaatattc atacaaaact ggtgaaaaaa ttcgtgttgc
    17221 aactaaacaa ggaatcaaat caactcgtga agtgattgcg ttgaacgttg ctggtgctct
    17281 tgatatctat gatgatgttg aagttggtcg tcaagttttg gttgacgatg gtaaacttgg
    17341 tcttcgtgtg gttgctaaag atgatgcaac tcgtgaattt gaagttgaag ttgaaaacga
    17401 tggtatcatc gctaaacaaa aaggtgtgaa catccctaac actaaaattc ctttcccagc
    17461 tcttgctgaa cgcgataacg acgatatccg tttcggtctt gaacaaggta tcaacttcat
    17521 cgcaatttca ttcgtacgta ctgcaaaaga tgtgaacgaa gttcgtgcaa tctgtgaaga
    17581 aactggaaac ggacatgttc aattgttcgc taaaatcgaa aaccaacaag gtatcgataa
    17641 cttagatgaa atcatcgaag cagctgatgg tattatgatt gctcgtggtg atatgggtat
    17701 cgaagtaccg ttcgaaatgg ttccagttta tcaaaaaatg attatcaaga aagtcaatgc
    17761 tgcaggtaaa gttgttatca ctgcaacaaa catgcttgaa acaatgactg aaaaaccacg
    17821 tgcaactcgt tcagaagtat cagacgtatt caacgctgtt atcgacggaa ctgacgctac
    17881 aatgttgtca ggcgagtctg caaacggtaa atacccactc gagtcagtaa ctacaatggc
    17941 tacaatcgac aagaacgctc aagctcttct taatgaatac ggacgtcttg attcagattc
    18001 atttgagcgt aactctaaga cagaagtaat ggcttctgct gttaaagatg ctactagctc
    18061 aatggatatc aaattggttg taactcttac taagacaggt catactgcac gtttgatttc
    18121 taaataccgt ccaaatgctg acatcttagc attgacattt gacgaattga cagaacgtgg
    18181 cttgatgttg aactggggtg ttatcccaat gttgacagat gctccatctt caactgacga
    18241 tatgttcgaa atcgctgaac gtaaagcggt agaagcaggt ctcgttgagt caggcgatga
    18301 tatcgttatc gttgctggtg tgccagtagg agaagctgtt cgcacaaaca caatgcgtat
    18361 ccgcacagta cgttaagaaa aatataaaaa cctatcatat ccagctttct agcctgtatg
    18421 atgggctctt tttttgtcca gggggcaaaa agggggcaaa actttcataa tggattgata
    18481 ctcttcgaaa atcaaattca aaccacgtca gcgtcgcctt accgtatata tgttactgac
    18541 ttcgtcagtt ctatctacaa cctcaaagca gtgctttgag caacctgcgg ctagcttcct
    18601 agtttgctct ttgattttca ttgagtatga aataagatat gcataaattg attagaaagt
    18661 caaatgaatt tctacaaatg ttttagcaat cgcaatctac ttgtctagat tcgatctgat
    18721 atattttcga tttaatgata tggtatttaa aacctccaaa gtagcttgct ccattctttt
    18781 acctacgtga gtctagatgt tatttactgt tttagcgttt ttgtgttcta ctctaaccat
    18841 tatagcattc ttctcagcta gtgtactaag gagtgtgtgc ctgaaaatat gggaactaag
    18901 gggctggttt atcggtttct ctagtttagt atttgccttt tgcaaagtga tcttaaatgc
    18961 ctttctctaa atttacatat cactattgtt taacaaaatc taatctattt taggtcactt
    19021 attctttttt tgaaatgtag aatgaacttt ttcaaagttt ttcgaatctt ttaaaatctg
    19081 tttgttttat atcgccattc tccccctttt ttaattctcc ctatatagcc tgacaacttt
    19141 tccgatggta cgaatatggt tgctttcgtc taggtggatg tcggagtatt cgggattgag
    19201 tttttttgag gtagccttgg cggagtttct tgacatagtt agtgccgtct acttggaaga
    19261 tgccgatggt attatagtca atctgtgggg tattcttgat aaataggtag tcgctgtttc
    19321 ttatctttgg ctccatggac ttgctgacga cataagcgat tgggtcgtag tcgtctggga
    19381 taatggaaac tccataacta aatcgtcgtc ctgcatcaag cggctacctg cagagataaa
    19441 ctacctaaca cgagagtaag tagtctgtct gtagtcgtcc agtctgatga tttttacgat
    19501 acttcgtttt tctgatcata cagttgcctc tcggcatagg tcagaacttt accttgtctg
    19561 ggtggtgccc gttggtcgta gatagattgg atatcgctag gagaatcctt ttgaactgga
    19621 ggaaagaggg catcaatcaa gctactgaat actttaacta agtcaaatat agtatttttc
    19681 ttagtagacc taaccctttt ttcataattt ctaatggtgt ttttacttat acctatctta
    19741 gtacccaatt cttattgagt ccaaccatta ctagtctata ttgttttata gttgattgag
    19801 tttggaatag tacgctgtag ctgctaaaac atttctagga attaatttgc ctttcctaat
    19861 agagttgttc atatcttatt tcaatctact atatttttca cctctaacaa tcgcaatctc
    19921 ttctttatcc atgaacgaaa acgctttcta tctttgtaag taaagcatca cacgaaatcc
    19981 acgaaaatga aaacctttgt tgtgttttcg taaaaaattt gttgacagag cacgaaacgc
    20041 ctactataat taaatcaagt ttaaggaaat aacaaaaaaa caaatcggag ggaaagacga
    20101 tgaacacatt aaatgagaaa gtaatcaata tctgtaaagc agtagttaaa gaaactttaa
    20161 tccaagacat ttaggagaaa gaaatgaaga aatcaagaaa attagccaca ttaggaatct
    20221 gttcagcctt gtttttaggc ttggctgctt gtcaacaaca acatgctact tctgagggga
    20281 cgaatcaaag gcaaagcagt tcagcgaaag ttccatggaa agcttcatac accaacctaa
    20341 acaaccaggt aagtacagaa gaggtcaaat ctctcttatc agctcacttg gatccaaata
    20401 gtgttgatgc attttttaat ctcgttaatg actataatac cattgtcggc tcaactggct
    20461 tatcaggaga tttcacttcc tttactcaca ccgaatacga tgttgagaaa atcagtcatc
    20521 tctggaatca aaagaagggc gatttcgttg ggaccaactg ccgtatcaat agttattgtc
    20581 ttttgaaaaa ttcagtcacc attccaaagc ttgaaaagaa tgaccagttg cttttcctag
    20641 ataatgatgc gattgataaa ggaaaggtct ttgattcaca agataaggaa gagtttgata
    20701 ttctattttc gagagttcca actgaggcaa ctacagatgt caaggttcac gctgaaaaga
    20761 tggaaacatt cttctcacaa tttcaattca atgaaaaagc tcgaatgctg tctgtagtct
    20821 tgcacgacaa tctggatggc gagtatctgt ttgtaggcca cgttggggtc ttagtacctg
    20881 ctgatgacgg tttcttattt gtagagaaat tgactttcga agagccctac caagcgatta
    20941 aatttgctag taaggaagat tgctacaagt atttaggcac caagtatgcg gattatacag
    21001 gcgagggact ggctaagcct tttatcatgg ataatgataa gtgggttaaa ctttaatagt
    21061 gttatgatat gacagtaatc ttaggatttt tatttctatt tttgataagt tggtgggtta
    21121 tttcaatcgt taatagccag aaaccacgca aaaatgaaac atttattggc tatgtccaaa
    21181 gatacgatat tgatgggaat ggctatcaat cattaccgtg tcctcagaac tgagaggagt
    21241 tcttgaaatc gtaacaccac tttgaacaag agttacttaa acccattggc tccgacggat
    21301 taagttgctt tcgtgaatac caaaatcagc cgcaatttct tcataagtgc ggtattctcg
    21361 cacatattga agagtggcca taagaaggtc ttctaggctt aatttaggtt ttcgtccacc
    21421 ttttgcgtgt ttaagttgat aagctgtttt taatacagct aatatctctt caaaagtcgt
    21481 gcgctgaaca ccaacaagac gtttaaatcg tgcatcagtt agttgtttac ttgcttcata
    21541 attcatagaa ctactatacc atattttgtt tcgcaggaag tctaatgcta aaatcttatc
    21601 agtgagaaga tttcttaaag tttattcttt gtagtttcat ctgtattagt acataattta
    21661 acttagagaa aataggagga ctaatcgaat ggaattaaaa gattttacag aaaaagaaca
    21721 ggaaatgatt aagaaaaggc ttacaatgtc taatattagt gacaaagaaa ctactgagaa
    21781 gattctggcg ctagtcccac aagacttgat taagcgaatc ccgttttttg tcagaaaaca
    21841 tgctacaaca cgtacgatta aacgcatttc aattgaatac cctgaactct acgctgtagc
    21901 tcaaacaagt ggtgagattc cagaaaaaaa acgcgaagaa ttgcgtcaga ttatcacaac
    21961 tatctttgaa caaaagatga ataagcatag tattaagtag agaatgaaaa aatattttat
    22021 tggcggtttg ggaagcaatg cctatcatag caaggatttt cttcaagaac tagattcgca
    22081 ggtctatttt ctaaatccat atgaaaagca tcttcgagat gaaacagaat tgaaatcatg
    22141 gtttaaaaat gaaattgtag aggaagaatc tatctgtctg ataggccatt ctcttggagg
    22201 agatttagct cgttatttcg catcggaatt tgaagaagta aagaaactga ttcttttgga
    22261 tggtggctat ctagatttag ataagatttt acctttggat acagagttag aggaaactaa
    22321 aaattatatc aaatctcaaa ttgtttcgga cttagatgtt cttacttcta aagaaaaatc
    22381 tgaagcaaag cattggtcag aaaatatgga gaaagctgta agacagtctt atcactggaa
    22441 tgttgagtat aatagatatg agttggctat aaattatgaa aatatagaag cgatactccg
    22501 cctacggaga aaaatacaag cttttaagag agaagtggga gataccttgt ttattagtcc
    22561 tcgctatcct aatgaagcta catggagaga ggaagcccta aaagaattgc cagactattt
    22621 tgatactatt tttttagaaa actttggcca tgagctttat actcaagcac ctaaagaaat
    22681 cgctagtcta atgaatgagt ggctcgctta ttttctatga gctacttgta ttgctgggaa
    22741 tggtataaga tgaaaatcta caagtcacta attttcatat aacaaaaaac gaacaggctc
    22801 tttttctgtt attcagaaga gaacttgttc gtttttatct tgattttctt aaaaagctct
    22861 atatacatag ggattttctg gtttatcgac tttggtaaag ctgtcgattt ccaaggttgg
    22921 aaggttttgt ttgagttctt tatggtagtg attgaccagt tttcctttgg ctgttatcca
    22981 agtgttgttt tcatactgcc gggtattgcc cttggtcagc aatccataga caccagaatc
    23041 tgcgatacag tggataatgc cgaatcggaa cagaaattga ctattggcat gactggggtc
    23101 gttatagaca aagcctgtaa actggattgt cttgccctca aactcatctg gatagtcgta
    23161 gatagcctcc atgacttcca tatagttttc attagtgatc tgaatactat cttgggataa
    23221 gtatttatcc gccgccgttc gcatttcctt ttcataggct gattttgaaa aataagaact
    23281 agtatctggt ttcaaatatt ggcttgtagt cccttcactt gtctgaatag ccagattcgt
    23341 tccttccgat agagggaaat gatagccttt agctgaaaca gtctgagaat ccaagctaac
    23401 agttgggaaa gttaagccga tgacaagtgg aatagccaga agagaaatac tcgtcatctt
    23461 ggccaatcgg ctgttcagat gactgtgggt tttgacttgc ttcatccaga tatacaattg
    23521 aacgatagcc aagataaaag aaagcaccat ggagatatag gccagatagg aatagtgcat
    23581 gttgatgtac tggtttagtt tgcccgacag atggaggtaa atagtcagtt caaaatagcc
    23641 agctaaaact aaaaatcgaa tcataggatg actccaatca agagagaata gactaagacg
    23701 acaagagtta caattgttat gaagtgactg ataaatcgtg ctttcaagta atttttcatc
    23761 atgagaatat ttttgatatc cagcattgga ccaatgacga gaaaggccag aactggtgcc
    23821 aaaccgaaac tcgagagaag agaagcacct ataaaggcat ccgcctcact acagagcgaa
    23881 agaagaaagg ctaaaatcat caagagcagg atggcaaaaa gaggggtcgc actgatagag
    23941 gtcagaatcc gagtcggaac gtagacctgt attatagaag caaagaggca gccaaatacc
    24001 aaataacgcc ccgtatcaaa aaattcatca atggcctgca caaagacttg aaaaactttt
    24061 tttgcagaac tcaagtaaga aaaatcatgc tcatgacaag ccagacgatt ttctttctga
    24121 atcggttctt gccagaaaaa tcctagaaaa attcctagta ttacagccac aagaatggaa
    24181 cccagagctc gtaatagtgc gacatggaag gagttgccaa aggcagaata ggtcgcaaaa
    24241 agaacaatgg gattgataac aggtgctgtc acaagaaaag gaacggccgt gtaacttgga
    24301 accttttttt ccagaaaacg attgatgatg gggacgattc cacattcaca agaagggaaa
    24361 agtataccga caaaggtccc aaaaaagatt ctcccccaac gatttcgagg gagaaaatga
    24421 taaaccttgt caggtgtgat ataaacttca atcagccctg agacaatgct tcctatcaga
    24481 acgaagggaa gggcttcaat gataatggag agaaaaatgg ctccagtttg aagtacacta
    24541 gatgggagtt gttgaaaagc agtcatctag tttttctttt ctgctttgac ttttttctct
    24601 ttgtcatcag ggaaagtaac ttgtttcaaa tcagggagtt tagcaaactc ttcaaacatc
    24661 ttgtccaagt cgtctcgttt tgtaaatttg acagccatag gtgtacctcg attctaaatt
    24721 ctacctctat tatactatta ttttgcggaa aagggaaaag ttaaaatttc aaattgagta
    24781 gctaagagat aatatagctt gatattacct gatatatatc ataattgtgc tataattaaa
    24841 taaaaagaaa atcattatca gaaaattatg ggaggtagtc aaactgactt actcaattag
    24901 tgttgttttg ttacatcaag gagataaaaa tagtttatta gagtctttgt caatagtgga
    24961 gagacaaaca ttaaaagata tagaagttat tattgtaaat caatctacag aggagatagc
    25021 ttccattagc caacagatga atctatcatt taatattaag attatagatg agaattcttt
    25081 tgctgagttg tctgatatga ttacaggaga ttatattacg tttctatctt caaatgattc
    25141 attatttgat tggacatttg aaaagatgta tcatgcgata aaattatccg attctgatgt
    25201 tgttcttggt catttttctg atttggttga tggagtattt tacttttatc cttgggggga
    25261 taattggttg acagaaaatt taacgaatgt tcaagtttta caaaagatgg atgatacaga
    25321 tcatcgaatt agaaaacaat atcgctcatt atttggaaaa ttattcaata gtaagctttt
    25381 acgaaaaata aatcaatttg atataaacaa ccttatttgg agactttata ttcactctaa
    25441 aactgcaacc tatattaatt tcccgacata tatctataaa cctgttatag atgctaaacc
    25501 tctaaaagac tcctacaaaa tcatattaga aaattatgaa aatagaatca aagattgcgc
    25561 cgtcttagaa aactatgata tagaaagagc gaaaaaacaa tatattcaag aattggcaaa
    25621 ttttagtgct tggttaaaaa atgacggtga atatttagat tctgatattg tttatcataa
    25681 gttaatagct gcagagaaag gaattttccc ttttcttgag cttgatagat tagattttac
    25741 gattataagt aataattgtg ttggaggatt aatttataga cagcttggtt ttcaatatag
    25801 aacacctttt gttggtttat ttattcttcc tgatgattat tataaactta caaagcattt
    25861 tcgttattat atggaacaag aacttgtttt cgaagaggaa cttatttcac cgagctggac
    25921 tcatgaagtt tatcctttgg ggcacttagg agatatagat attcattttc tacattattc
    25981 tagtattgaa gaagcacgaa ctaagtggga aaaaagaaaa aaacgcataa attggaataa
    26041 tctttatttt aaatttgata ataaagattc agctagtgaa gaaattttaa ataagatgga
    26101 taatcttcct tattctaata aattaatttt agtcaatcgt ccatataaaa atttgaaaag
    26161 tcaatgtgtt attccaggtc aggaacatct tccagaactg gctattatgt ctgatccatt
    26221 aaatactttt gatatcatgg cttggttaaa aaaaggtggc aatgctcttt aagtgcaagt
    26281 tattgcgctg tagcatataa atctatttcc tacatatttt ttaaatgttc tacgagttaa
    26341 tttgaaacgt ttagcttgtg gtataataga tttatggata aaaaatatga aaaaatctct
    26401 caggatttgg gagtgacgtt aaagcaaatt gataccgttc taagtttgac agctgaaggg
    26461 gcgactattc cctttatcgc gcgttatcgc aaggacatga ctggtagtct ggatgaggtg
    26521 gcgattaagg ctattattga tttggataaa agtctgacaa atctcaatga ccgtaaggaa
    26581 gctgtcttag ctaagattca agaacaaggt aagttgacca aggaattgga agaagctatc
    26641 ttagttgccg aaaaatcagc agacgttgaa gaactctatc ttccttataa ggaaaagcgt
    26701 cgtaccaagg caaccattgc ccgtgaagct ggactctttc ctcttgctcg cttgattttg
    26761 cagaatatag ttgacttaga gaaagaagct gaaaagttcg tctgtgaagg atttgcgact
    26821 ggcaaggaag ctttgaccgg tgcagttgat attttggtcg aagccttatc ggaagatgtg
    26881 accttgcgtt ctatgactta tcaggaagtg ctgagacact ctaaactcac ttctcaagcc
    26941 aaggatgaaa gtcttgatga aaagcaggtt tttcagattt attatgattt ttcagagaca
    27001 gttggaacta tgcaaggcta tcgtaccttg gctctcaatc gtggggagaa acttggtgtc
    27061 ttgaagatcg gttttgaaca tgcgacggac cgtattcttg ccttctttgc tactcgtttc
    27121 aaggtgaaaa atgcttatat tgatgaagtt gttcagcaat ccgttaagaa aaaggtcttg
    27181 cctgctattg agcgtcgtat tcggacagaa ttaactgaga aagctgaaga gggagctatc
    27241 caactttttt ctgacaattt gcgcaatctc ctcttggttg ctccactgaa agggcgcgtg
    27301 gttcttgggt ttgacccagc ctttcgtaca ggtgccaagc tagctgtcgt ggatgcaaca
    27361 ggaaaaatgc tgacaactca ggttatttat cctgttaaac cagcatcagc tcgtcaaatc
    27421 gaagaagcca agaaagattt agcagattta attggtcaat acggtgtaga gattattgcc
    27481 attggaaatg gaacggccag tcgtgaaagc gaagcttttg tagcggaagt tctgaaagat
    27541 ttccctgaag tcagctatgt tatcgttaat gaaagtggtg cttctgtcta ttctgccagc
    27601 gaacttgctc gtcaggagtt tccagacttg accgttgaaa aacgctctgc catttctatc
    27661 gcccgtcgtt tgcaagatcc tcttgcggaa ttggtcaaaa tcgatcctaa gtcaattggt
    27721 gtcggtcaat accaacacga tgtcagtcag aagaaactat ctgagagtct ggactttgtc
    27781 gtggatacgg tggttaacca agtcggtgtc aatgttaata cagctagccc agctcttctt
    27841 tctcacgtgg ctggactcaa taaaacaatt tctgaaaata ttgtcaaata ccgtgaggaa
    27901 gagggaaaaa tcacttcacg ctcccaaatc aagaaagttc ctcgtttggg ggccaaggct
    27961 tttgaacagg ctgctggttt cctccgtatc cctgaaagta gcaatatcct tgataataca
    28021 ggagttcacc cagaaaatta cgctgccgtt aaggaactct tcaaatgctt ggacattaag
    28081 gatctgaatg aagaggccca aagcaaactc aagtcgcttt cagtcaagga aatggctcaa
    28141 gagctagacc tcggtccaga aacccttaaa gatatcattg cagatcttct caaaccaggt
    28201 cgagatttcc gtgattcctt tgacgcacct gtgcttcgcc aagatgtcct agatatcaaa
    28261 gacctagtgg taggtcagaa gctagaaggt gttgtgcgta acgttgttga cttcggtgcc
    28321 ttcgttgata tcgggattca cgaggacggc ttgattcata tttctcatat gagtcgcaag
    28381 tttatcaaac accctagtca agtggtggca gttggagatt tggtgaccgt ttgggtcaag
    28441 aaaattgata ctgaacgtga aaaagttaat ctgtcgctcc tcgctccaaa tgaaactgac
    28501 tgattatgtc aagcaggttt cactagaaga cttcgggaga gcttttatcc atcatgtcca
    28561 gtggaatagg cgtctacgtt cgacaggtgg gcgatttttc cccaaagatg ggcatctgga
    28621 ttttaatccc aaggtttatc agaaactggg tatggaggtt tttaggaaaa ttgtccgaca
    28681 tgaactctgt cattatcacc tttatttcca agggaagggc tatcaacaca aggatcggga
    28741 ttttaaggaa cttttgaaag cagtggatgg attacggttt gtaccatcct tgcccaatag
    28801 taactctaaa ccactcaagc tttatcgttg tcaatcctgc cagcaaaggt atcagcgcaa
    28861 gcgtaggatt gataccaaac gctatcgctg tggactttgt cgaggtaaat tgcttctgat
    28921 aaatcagcct gaggactgat gaaagccgag cctccccgtg atatactatg tctaacctag
    28981 cagaaagagg aaatatcatg aacagtaaat tttataaaat gagacgcaat cgcatgattt
    29041 caggagttct ggcaggtctg tcagacaagt ggaattttga tgttacccta gttcgtttct
    29101 tgtttgctat ttttacagtt gcaaactttg gacttggcgt gattatctat atcatcctag
    29161 cttctatcat gcctaccaag gaagaaatcg aagcagaaat gtacggaaca ggcccacgta
    29221 aacgcaaaga agcccaagcc attgacgaca atgaaggctg gttttggtga ggttctacag
    29281 aagatttgga ataagcaaaa agctttaaat caatagtcta aactgcttga tttaaagctt
    29341 ttttactttt atactcaata aaaatcaaag tgcaaactag gaagccagcc acaggctgta
    29401 atttagtcgg caatgtgaag ttgacatagt ttgcactttg atttttgaat agtattaata
    29461 atatttcgcc agcttcatcc acaaactata gtggattgga actagaatag gacacctcta
    29521 cttctaaaac attgttagaa atcgatttga ctatcctgat cgatttgtcc tgttcttatt
    29581 tcattttatt ataaaagcag taatttaaac tcagtttttt aatctatttt tgctgctgag
    29641 acaatacatt tttggaaaaa tggtggatgc tgataacaac tgataaccag caaataacat
    29701 aagcagtgcc ggtaaattct gtaccgataa agtgtgtgtg ttcaactaag agctgaccga
    29761 tgaatggaga gagcagatag agaagtccga tgagtatatg ttctttgtgt ttcattaaag
    29821 cgcaccttct ttccttatag gttgaacgac ttgcaagtgt taaattgaat ggtatgttat
    29881 ctaggtaacc ttactaaaat gttagttccc gcttcctcct tttcaaagta agccttttca
    29941 cacttatatt ttacaacttt aaaaatagga aatcaaatca ttttctaagt aattttgctt
    30001 atatttcacc caatcttaca aaaatgtaag attaaagtct cttttgtaag gttaggttat
    30061 ggcaagcggt ctttttttga tgtaaactag actcataaag aacaaaggag taacatcatg
    30121 aaacaaatct tacataagaa aactagaaaa ccaagtcaca aagaaattga gcgcgttcag
    30181 ctgggatgca ctatgatgca agctacattt catttgatgg gatattaaga aaggagattc
    30241 tcatgacact tttagatgta aaacacgttc aaaaaattta taaaacacgt tttcagggca
    30301 accaagtaga agccctcaag gatattcact ttaccgtcga aaagggtgac tacgttgcca
    30361 tcatgggtga gtctggttct ggtaaatcaa ctcttctcaa tattctagct atgctggata
    30421 aaccaagtcg tggtcaggtt tacttgaatg gaactgacac cgcaaccatt aaaaattcac
    30481 aggcctctag cttccgtcgt gaaaagttgg gctttgtctt ccaagacttt aacttgctag
    30541 atactctatc tgtaaaggac aatatcttgc ttccgcttgt cttgtcaaga agacctatta
    30601 cagagatgat gaagaaattg gtggtgacag ctgagaatct gggaataaac caattacaag
    30661 agaagtaccc ttacgagatt tctggtggtc agaaacagcg tgtagcagta gcccgcgcca
    30721 tcatcacaga acctgaaatt ctccttgcgg acgaaccgac aggagctctt gactccaagt
    30781 catctgcagc cttacttgat gtctttgatg aaatcaatga gcgcggccaa accattctca
    30841 tggtaaccca ctcaacagca gcagctagca gagctaaacg tgtactcttt atcaaagacg
    30901 gcattcttta caatcaaatc taccgtggag agaagacaga acgtcagatg ttccaagaaa
    30961 tctctgatac cttgactgtc atggcaagcg aggtgaatta gtatgtttcg attaaccaat
    31021 aagttagcgg tatcgaactt gattaaaaac cgcaaactct actatccttt tgcgctggct
    31081 gttctcttgg cagtcactgt cacctatctc ttttactctc taaccttcaa tcctaagatt
    31141 gcggaaatcc gtggaggaac aaccattcag gctacacttg gatttggtat gtttgtcgtc
    31201 acccttgcgt cagccattat cgttctctat gccaatagtt ttgtcatgaa gaaccgttcc
    31261 aaggaactag gaatttatgg catgttgggc ttggagaagc gtcatcttat cagtatgacc
    31321 tttaaggagt tagtggtatt tgggattcta actgttggag cgggtatcgg tattggagcc
    31381 ttgtttgaca agttaatttt cgctttcctg ctcaaactaa tgaaattgaa ggttgagctg
    31441 gttgctacct tccagacgaa agttgtcatt acagtacttc ttgtcttcgg tttgattttc
    31501 ctaggcctca tgttcctgaa tgcccttcga atcgcccgta tgaatgccct ccagctctct
    31561 cgtgagaaag ctagtggaga gaaaaaaggt cgcttccttc ctctccaaac cattcttggt
    31621 tccataagtt taggaattgg ctattatctt gcccttacgg taaaagatcc tcttacagcc
    31681 ttaacaacct tcttcatagc tgttttactg gttatctttg ggacttatct cttgtttaat
    31741 gcagggatta ccgttttcct ccaaatctta aagaaaaata agaaatacta ttaccaacca
    31801 aataacctca tatctgtttc taacttgatt ttccgtatga agaaaaatgc agttggacta
    31861 gccaccatcg ctatcttgtc aacaatggtt ttggtaacca tgtcagcagc gacaagcatt
    31921 ttcaattcct cagaaagctt taaaaaagtt ctaaatcctc atgattttgg ggtttcaggg
    31981 caaaatgttg aaaaagaaga cttggacaaa ctcttgagcc agtttgcaag tgacaaaggt
    32041 tataagatta aagaaaaaga agtatttcgt tacacttact ttgctgttgc gaatcaagaa
    32101 ggaaccaagt taactatttt tgaaaaagga caaaaccgtg tccaaccaaa aacagttttc
    32161 atggtatttg accaaaaaga ttatgaaaat atgactggtc aaaaactgtc tctatcagga
    32221 aatgaggtcg gactctttgc aaagaatgag ggagttaaag aacagaaagc tctaactcta
    32281 aatgatcatc aattttctgt aaaagaagaa tttactaaag attttattgt caaccatgtt
    32341 ccaaatcagt ttaatatttt gactgctgat tacaattacc ttgttgtacc tgatttacaa
    32401 gcctttttgg atcaattccc agattcggct atctataatc agttttacgg tggtatgaat
    32461 gtaaatgcca gtgaagcaga acaactcaag gtcgctgagg agtatgaaaa atacttacaa
    32521 aagtttaatg ctcaattaaa cactgaaggt aactatgtgt atggtagcac tctagcagat
    32581 gctagtgctc agatgagtgc cctctttggt ggtgtcttct ttatcggtat tttcttatcc
    32641 attatcttta tggtcggaac cgttctggtc atctactaca aacaaatttc tgaaggatat
    32701 gaagaccgtg agcgctttat tatcttgcag aaagtcggtt tagatcaaaa gcaaatcaag
    32761 caaaccatca acaaacaggt tttaactgta ttcttccttc ctttgctctt tgccttccta
    32821 catctagcct ttgcctacca tatgcttagt ctgattttaa aagtgattgg tgtactggat
    32881 acgactatga tgttgattgt gaccttgtct atctgcgcta tcttcctcat cgcctatgtg
    32941 ctgattttca tgattacttc aagaagttat cgtaagattg tccaaatgta aaaaaagata
    33001 cctcgacttc aaaatcgagg tatttcttgt tttctaaatg ctgaaaagtt gtccgagcag
    33061 aaaggtaact cccatagtta agagaccaat agcaaggttc cgaatcatag ctgttttggt
    33121 tggggctttt ccaagtctag cacttgtgta accagtgaga agaagggcca caccgacaat
    33181 aaggacggta gcagggatgc ggtaatcact tggaaaaatg gtcactgaca gcattggagg
    33241 caaacttcta aggaaaaagg caacgaagct agaaatggca gcgtgccaag gattggtaaa
    33301 ttcttcatac tcaatcccat atttttcctc taccagagcc ttgagtggat ttttaagaaa
    33361 gatcttattg gtcaagagtt gggcagaagt tttgaattct ccattttgga tataagcagc
    33421 atagagggat tttttggcta gttccctatc ttggtctagc aagagttttt ctcgcgaaac
    33481 ggcagcttcc tcggtatctt ttggagttga aacggataca tattctccac cagccattga
    33541 aaaggcacca gctaagatag ccgtaaaacc tgataaaaag ataatccaga tattggtcgt
    33601 ggcactggca actccgataa ccacaccagc aatggaaata attccatcgt tagcatcaag
    33661 aacacccgca cgcaggatat ttaaacgacc tgcaaaattt gaatcaattt cgtgatttgt
    33721 ttctgacgct aaatttcaag ttcaagttag ccatccagaa gtcttctctg ggtgacttgt
    33781 agtccaagca ttttttagga tagttgttaa tccacttttc gatgaatgcg acttctttgg
    33841 gagtcatttt cttggttccc ttaggtaacc atctatgaat gagcctgttg tgattctcat
    33901 tagttcccct ttcccaagag gcataggggt gcgcataata aatgtgctcc tcagaaaata
    33961 catcagacaa gcgattgaat tccgttccat tatctgccgt gatggaaaga atcttgtgtt
    34021 gttttaagat gagttttaga gcctgattga ccacctcagc acttttattt ggaatcaatc
    34081 ggatgatctg atgtctactt tttcgatccg tcaagacaag caagcagtag tttttcgctc
    34141 tcgtaagtag aaccgtatca atctcataat gcccattctc caagcgaaaa ttgatagctt
    34201 caggccgctg ttcgatggat tgaccagcag gtttaaagtt gatgctagcc tgtttcttat
    34261 caggcgaaaa tttttggtta tgatagtgga gaatcttttc ctttagttcc ttggtcacgc
    34321 ttgatttcct gaccgagcgc ttgcaattgt tttcataaga ctgttgagca tagtcggcag
    34381 aataaacctc tttgaagcgc ccttttccaa gacattgtcg gactgtccca cgcttgattt
    34441 cagtgtggat agtttgagga acttttccaa gcagagaggc aatttctcta tttgatttcc
    34501 cttctttttt ccatctttcg attaagcgac ggctatcgat tgtcaaatgt ttggcttttg
    34561 tagtataatt gtcttgcatc tctgtgcctt tcttgtgttt gtggttgaac aacaagtata
    34621 acacagaggt gttttcttat gcctacaaga gctatcagct agttgaacca tctaattttt
    34681 aggaggactg ggtggctaac ttcattatag aactttcatt tacgaacata tagtaaaatg
    34741 aaacaagaac agaacaaatc gatcaggaca gtaaaatcta tttctaacaa tgttttagaa
    34801 gcagaggtgt actattctag tttcaatcta ttatattttt gttttttatc aaaaaatact
    34861 ttacaagttc ttaaaaacat gatatagtaa taaagcttag aaaatgagat gatgttttct
    34921 agcaaatata aacccgagta aaaaatgcct acggacaggc agggttgaat gccgaagcgt
    34981 ggttgaaaag ccacattatt gatagggtta aaagcctact tttataagtt gatgttagga
    35041 cacttgtcct aattcataaa tttttagtgt ggtgaaagca cacgtcatct tgtgaaacga
    35101 tcaataaagt acgtaatatt tgctactaga gagttaggaa acatcgggaa cagacatact
    35161 caacagaaac caaaataaac acgtcagaag attgcagagc aggtgaaaac ctgctctttt
    35221 ttcatgagtc aacctttagt tccttagttt tcataaggtc ctaaaaatat tgaaaggagt
    35281 atgttttgaa agagttagat caaaaccaag ccccaattta tgaggccttg gtgaagttgc
    35341 gcaagaaaag gattgttccc tttgatgttc caggtcacaa gcgtggacgg ggaaatccag
    35401 aacttgtcga actcttagga gaaaaatgtg taggcattga tgtcaattcg atgaaaccct
    35461 tggataattt aggccatcct atttcgatta ttcgtgatgc agaggagctg gctgcagatg
    35521 cttttggagc tagccatgcc tttctaatga ttggtggaac aacttcatcg gtgcagacta
    35581 tgattctggc aacctgcaag gcaggagata agattattct gccacgaaat gtccataaat
    35641 ctgctatcaa tgcgttggtt ctatgtggtg ccattcccat ctatatcgag atgagtgtag
    35701 atcctaagat tggtatcgct ttaggtcttg aaaatgaccg agtagcacag gccataaagg
    35761 accatccaga tgctaaggct atcctaatca acaatcctac ttactacggc atctgttcag
    35821 acctaaaggg gttgacagaa atagctcatg aagctggcat gatggtttta gtagatgaag
    35881 cccacggagc gcatttgcat ttcactgata aacttccaat ttctgctatg gatgcagggg
    35941 ctgatatggc agcagtttcc atgcataagt ctggtgggag tttgacccaa agctccattt
    36001 tacttatcgg ggagcagatg aattctgaat acgttcgtca gataattaac ctgacccagt
    36061 ctacatctgc ctcttacttg ttgatggcta gtttggatat ttcacgtcgc aacttggccc
    36121 ttcgtggtaa agagtcgttt gaggaagtca ttgagctatc tgagtatgcc cgccgtgaaa
    36181 tcaatgctat cggtggctac tatgcctact caaaagagtt aatagacggt gtttcggttt
    36241 gcgattttga cgtaactaag ctgtcagttt acactcaggg tattggctta acaggtatcg
    36301 aggtttatga cctcttgcga gacgaatacg acattcagat cgagtttggt gatatcggca
    36361 atatcttggc ctatatttcc atcggcgacc gcatccaaga catcgagcgc ttggttggtg
    36421 ctctggctga tattaagaga ctctattcaa gagatggaaa agatttgata gcaggagaat
    36481 atattcagcc cgagttagtg ctgtctccgc aagaagcctt ctattcagaa agaaaaagtt
    36541 tgaccttaga tgagtctgtt ggacaggtct gtggagaatt tgtcatgtgc tatcctccag
    36601 ggattcctat cttggctcct ggtgaacgta ttacacgaga aattgtagac tatatccaat
    36661 tcgccaagga acgtggttgc tccctccaag ggacggaaga tccagaggtc aatcatatca
    36721 acgttattaa gagaaagaca aactataaga aaagtcaata gttttatcta aactatttct
    36781 tatttcaatt tgatgatttg gcgatgattt tagagcacgg caaaaagccc ttgaattaga
    36841 agcggtcaat cgcttaattt ctatcagctt atcaaatcct gcctcaatcc ttttctgagg
    36901 attagggtag cgtgtcaaga gttggtaggt atattctgaa tgctttccaa cgattttatc
    36961 caactcagga aagatgatat caagacaacg agtgtattgt actttccaat cagactgttt
    37021 ttcttgagac gatgaatatg tctagccagt atttttaggt ctacttgccg attatcgtgt
    37081 tgaaattgtt cacgattggg gtcagaaaga agtttaagag cgatgccatg agcgtctttc
    37141 ttatccgttt tagtcttgcg aagtgataat gatttggcaa attccttgat gagcaaagga
    37201 ttgtaggtgt aaactttata tccttgttca tgcaggaagt tcagtagatt aaaggcataa
    37261 tgtccagtat cttcaagagc gatgagacag tcttggttga gctgtcgaag agacagatct
    37321 aagagttcaa aaccagcttt attatttgaa aaagtgagtg gtttaagaac agtttttcct
    37381 tgaacattca aggctgtaac atcgtgttta tttttagcga tatcaatgcc cacataaagc
    37441 atgggagtac ctccagatgt agtatttcaa gtctacttgg ttatccacga actttttgcc
    37501 ttgttacctt agacgagata aaacgtctat gcgttatcaa actcattacc aattgaaaca
    37561 aaagctgtgg ttagatcctt tcggaaatcg tcaagcgatt ggaggaaatg aactaatcca
    37621 cagtggctta ttccaagtat accacttggg ctttggcagt agctaactgc gctaaatata
    37681 atataaggag aaatagatgg atttatggtt ttctgaagtt catactccag atgtcaaatt
    37741 gtctctgaga acagccaagc aactttacgc tggaaaaagt gaatggcagg atatcgaagt
    37801 cttggatacg ccagcttttg ggaaaatact gattttaaat ggccatgtct tgttctcaga
    37861 tgcggatgat ttcgtctaca atgaaatgac cgttcacgtt cccatggctg tccacccaaa
    37921 tccaaagaaa gtattggtta ttgggggtgg tgacggcggt gttgcccaag tattaacact
    37981 ctatcctgaa ctggaacaaa tcgatatcgt ggaaccggat gagatgttgg tcgaggtctg
    38041 tcgtgagtat ttcccagact ttgctgcagg gctagatgat cctcgtgtta ccatttacta
    38101 ccaaaatggg ctacgctttt tgcgaaactg cgaagatgat tacgatatta tcatcaacga
    38161 tgcgacagat ccatttggcc atacggaagg actctttacc aaggaattct acggcaatag
    38221 ttatcgagct ctgaaggaag acggcatcat gatttatcag catgggagtc ccttctttga
    38281 cgaggatgag tcggcctgcc gaagcatgca ccgcaaggtc aatcaatcct ttccaatcag
    38341 tcgggtttat caggcccata ttccaactag cccagctggc tattggttgt ttggatttgc
    38401 atcgaaaaaa taccaccctg tcaaagattt tgacaaggaa ggttggaaaa aacgccagct
    38461 tttcacagaa tactacactg caaacttaca cgtgggagcc tttatgttgc ccaagtatgt
    38521 tgaggacatt ttagaagaag aggaaggaaa aaaatgagtc gtttactagt tattggttgt
    38581 gggggcgttg cccaagttgc tatttcaaag atttgtcaag atagcgaaac atttacagag
    38641 attatgattg ctagccgtac caagtcaaaa tgtgatgact tgaaagctaa actggaaggc
    38701 aaaacaagta caaagattga gacagctgct cttgatgctg acaaggttga agaagtgatt
    38761 gctctgattg aaagctacaa accagaagct gttttgaatg tagctctgcc ttatcaagat
    38821 ttaaccatta tggatgcttg tttggcaaca ggtgttcact atatcgatac agccaactac
    38881 gaagcagaag acacagaaga ccctgagtgg cgtgctatct acgaaaaacg ttgtaaggaa
    38941 cttggtttta cagcctactt tgactactca tggcagtggg cttatcaaga gaaattcaaa
    39001 gaagcaggct tgactgctct tcttggttct ggttttgacc caggtgtaac tagtgtcttt
    39061 tcagcttatg ccctcaaaca ctattttgat gaaatccatt atatcgacat tttagactgt
    39121 aatggcggtg accacggtta tccatttgca accaacttta atccagaaat taatctccgt
    39181 gaggtttctg cgccaggttc ttactgggaa gatgggaaat gggtcgaagt cgaagctatg
    39241 tctatcaagc gtgagtatga tttccctcaa gttggacaaa aagatatgta tctccttcac
    39301 catgaagaaa tcgaatcgct ggccaagaac attcctggag tcaaacgcat tcgtttcttt
    39361 atgacttttg gtcaatctta cttgacgcac atgaaatgtc ttgaaaatgt tggactcctt
    39421 cgtacggata ccattaactt taacggccaa gaaattgttc caattcaatt tttgaaagcc
    39481 ttgcttccag atcctgctag ccttggtcca cgtactgtag gtaaaaccaa tattggatgt
    39541 atctttacag gtgtcaaaga cggtgtcaaa aagactatct atatctacaa tgtctgcgac
    39601 catcaggaat gttacgcaga ggttggttcg caagctattt cttatacgac aggagttcca
    39661 gccatgattg ggacaaaatt agtcatgaac ggaacttgga aacaagctgg agtgtataac
    39721 cttgaggagt tagatccaga tccattcatg gaagctttga atgagtatgg tttgccatgg
    39781 gttgtggttg aaaatccaca aatggtggac taatgaagtt agaacaagta ccaacaccag
    39841 cctatgttat tgacttggcc aagttagaag ctaattgccg cattctacaa tatgtacaag
    39901 aagaggccgg ttgcaaggtc ttgcttgccc agaaggcata ttccctctac aaaacttatc
    39961 ccttgattag ccagtatcta tcaggtacga cagctagtgg actctatgag gccaaattgg
    40021 caagggaaga atttcctggt gaagtccatg tttttgcacc agctttcaag gatgaggaca
    40081 tggaggaatt gcttgggata acagaccata tcgtctttaa ctcagagaga cagttgcgta
    40141 agcatggggc tcgttgtcga gaggctggtg tcagtgttgg tttgcgcctc aaccctcagt
    40201 gttcaactca aggagatcac gcgctctatg acccttgtgc acctggttct cgctttggag
    40261 ttactataga caagattccg agtgatttgc tagatttggt tgacggactt cattttcata
    40321 ccctttgcga gcagggagca gatgatttac aaacaacttt gaaagcagta gaagaacagt
    40381 ttggtcccta cttacatgag gtaaaatggc tcaatatggg tggtggtcat catattacaa
    40441 gagaaggtta cgatgtggat ttgctgattt cagaaatcaa gcgtatccga aaaacttaca
    40501 atcttgaaat ctatatcgag cctggtgaag ccattgcgct taatgcgggt tatttagcaa
    40561 ctgaggtatt agatattgta gaaaacggta tggaaatctt ggttttagac gcctctgcga
    40621 cctgccatat gcctgatgta cttgagatgc cctatcgtcc acctttgaga aatggctttg
    40681 agtcacagga aaaagcccat acctacagac tttcttctaa tacctgtctg acgggcgatg
    40741 tgattggtga ttatagtttt gaaaatccag tccaaatcgg agacagactt tattttcaag
    40801 acatggccat ttattctttt gtcaaaaata atacctttaa tggtattgga ttgccaagtc
    40861 tctatctcat ggacgaacag ggagactgta gcttactcaa agcttttggc tatcaagact
    40921 ttaaagggag attatcatga tggacagtcc aaaaaaatta ggctatcaca tgccagcaga
    40981 gtacgaaccc catcatggta ccctcatgat atggccgact cgaccaggat catggccttt
    41041 tcaaggaaag gctgctaaaa gagcatttac tcagatcatc gagaccatag cagaagggga
    41101 aagagtctat cttttggtgg agcaggccta tctatctgaa gcccaatcct atcttggaga
    41161 caaggttgtt tatttagaca ttcccaccaa tgatgcctgg gcgcgtgata ctggcccaac
    41221 cattctcgtc aatgataaag gtaagaaatt agccgtggat tgggccttta atgcttgggg
    41281 aggcacctat gatggtcttt atcaagatta tgaagaggat gaccaagtag ccagtcgttt
    41341 tgctgaggcc ttggaaaggc ctgtctatga tgctaaacct tttgtactgg aaggaggcgc
    41401 aatccatagc gatggtcaag gaactattct cgtaactgaa agttgcttgc ttagtcctgg
    41461 tcgcaatcct aacctgacta aagaggagat tgaaaacaca ttattagaaa gtcttggtgc
    41521 tgaaaaagtt atttggcttc cttatggtat ttatcaggat gaaaccaatg aacacgtcga
    41581 taatgttgct gcctttgttg gtcctgctga gcttgttttg gcttggacag atgacgaaaa
    41641 tgatccccag tatgccatgt caaaagcaga tctcgaactc ttagaacagg aaacagatgc
    41701 aaaaggttgt cacttcacca ttcataaatt gcctatccct gcagttcgac aagttgtgac
    41761 agaagaagat ttgccaggct acatctatga agaaggagaa gaaaagcgat acgcaggtga
    41821 acgactagca gcttcctacg taaactttta tatcgccaac aaggctgtct tggttccaca
    41881 gtttgaggat gtaaacgacc aagtggcctt agatatcctc agcaagtgtt tcccagaccg
    41941 taaagttgtc ggaataccag ccagagatat tctcttaggt ggtggcaata tccactgtat
    42001 cacccaacaa attccagaat aggagaaaaa gatgagaaat gtaagagttg caaccattca
    42061 gatgcaatgc gctaaggatg tggcaacaaa tatccaaacc gcagagcgtt tagtacgtca
    42121 ggctgctgag caaggagccc aaattattct cttgcccgag ttgtttgaac atccctattt
    42181 ctgtcaggaa cgtcagtatg actactacca gtatgcccaa tctgtagcgg aaaatactgc
    42241 cattcagcat tttaaggtga ttgctaagga actacaagtt gttttaccaa tcagtttcta
    42301 tgaaaaagat ggtaatgtct tgtataactc tattgccgtc attgatgcag atggggaagt
    42361 gctgggcgtt tatcgaaaga cccacatacc agatgaccat tattatcaag aaaaattcta
    42421 tttcacgcct ggtaacactg gtttcaaggt ctggaatact cgctatgcta agattggtat
    42481 cggtatctgt tgggatcaat ggttccctga aacagcgcgc tgtcttgcat tgaatggtgc
    42541 tgaattgctc ttttatccaa cagccatcgg ttcagagccg attttggata cagatagttg
    42601 tggtcactgg caacgtacta tgcaagggca cgcagcagcg aatattgttc cagtcatcgc
    42661 agccaatcgt tatggtttag aggaggttac tcctagtgag gaaaatggcg gacagagttc
    42721 cagtcttgac ttctacggtt cctcctttat gacggatgaa acaggagcta ttctagaacg
    42781 agctgaaaga caagaagaag ctgttctgtt agctacttat gacctagaca agggagcgag
    42841 tgaacgccta aactggggct tgtttcgaga tagaagacca gaaatgtata gacaaattac
    42901 agattagtgt gggagaaatg agagattcat tctgctagac taacttctta ttagcaacta
    42961 taagatacta tggcatctag taaatcgatt tttatgattc gctattcttg tctattgatt
    43021 agtccgtatt ttaaaatatt agcaaaaaag caaatagcag taacttctgt ctatttgctt
    43081 ttctttttta tagaatatat ttctcaatag cacgcgcaac gccgtcttct tcgttgcttg
    43141 aggtaacggc atccgcaaga gatttgacat aatcgctggc atttcccatt gcaatcccaa
    43201 gccctgcaaa ctggagcatt tcgatatcgt tattagcatc gcccatggcc ataatctctg
    43261 aggaatcaat cttcaaaatc tcagctagtc gtgaaagagc agtagccttt gtcgttccaa
    43321 gtggcattgc ttcataaatg acaggctgcg aacgaactcc actgaatcgt tggcaaagct
    43381 cttcagcaaa acgctgctca aaatcgtctg tttgttcttt tgttcctaaa aacatacctt
    43441 ggaacatccg gaactttcca ctagtcgctt cctcaagaga aatttcagtc aggtctgaaa
    43501 atactagttt agcatcattt tcaataactt gattgggctt gccaccgaga acaaaataat
    43561 gtgactcgtc aaaaagtgtc aactgaacat cactcttttc agcaaggtca tagaggtatt
    43621 cgatgtcagc tggactcagt tcttgccagt caaccaagcc ccagtcgcta gtctggtgag
    43681 ttgaacaacc gttgttaaca atcacatatt cgttctggag gtcgagtccc agttttttgt
    43741 agtaggggag gacaccgaaa agggggcgac ccgtacagag gaccagtttg acaccttttt
    43801 caatggcttg gtgaatagca gcgatgtgag cctgtgggat ttccttggct tcattgagga
    43861 gggttccatc catatccaag gctagtagtt taatcatagg tcttccttct ttatcttttg
    43921 gtattattat agcatatttt ggagaagaaa ttgatagaaa gcttgagact aattgatttt
    43981 atagtttaag atgttttgat gacaattcat gatttgaaga ggatatttcg caaagatatg
    44041 ctatactatg tttgtcaatg ttgcaactag acaaattaaa aaaccaactt aatataatag
    44101 tttttttgta agtaggtatg agtatcagat
//
LOCUS       DAVMAH010000012        40402 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVMAH010000012 DAVMAH010000000
VERSION     DAVMAH010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.012"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            5..75
                     /locus_tag="VYO94_000581"
     tRNA            5..75
                     /locus_tag="VYO94_000581"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="VYO94_000582"
     tRNA            110..183
                     /locus_tag="VYO94_000582"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            267..356
                     /locus_tag="VYO94_000583"
     tRNA            267..356
                     /locus_tag="VYO94_000583"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:303..305,aa:Ser,seq:tga)
     gene            370..443
                     /locus_tag="VYO94_000584"
     tRNA            370..443
                     /locus_tag="VYO94_000584"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:404..406,aa:Met,seq:cat)
     gene            447..519
                     /locus_tag="VYO94_000585"
     tRNA            447..519
                     /locus_tag="VYO94_000585"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:480..482,aa:Phe,seq:gaa)
     gene            532..612
                     /locus_tag="VYO94_000586"
     tRNA            532..612
                     /locus_tag="VYO94_000586"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:566..568,aa:Tyr,seq:gta)
     gene            617..687
                     /locus_tag="VYO94_000587"
     tRNA            617..687
                     /locus_tag="VYO94_000587"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:649..651,aa:Trp,seq:cca)
     gene            702..774
                     /locus_tag="VYO94_000588"
     tRNA            702..774
                     /locus_tag="VYO94_000588"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:735..737,aa:His,seq:gtg)
     gene            785..856
                     /locus_tag="VYO94_000589"
     tRNA            785..856
                     /locus_tag="VYO94_000589"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:817..819,aa:Gln,seq:ttg)
     gene            866..949
                     /locus_tag="VYO94_000590"
     tRNA            866..949
                     /locus_tag="VYO94_000590"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:900..902,aa:Leu,seq:caa)
     gene            1056..2333
                     /locus_tag="VYO94_000591"
     CDS             1056..2333
                     /locus_tag="VYO94_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV1759262.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2409..3893
                     /locus_tag="VYO94_000592"
     CDS             2409..3893
                     /locus_tag="VYO94_000592"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV1759263.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLNF
                     NKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALRERLAA
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLIDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3954..5234
                     /locus_tag="VYO94_000593"
     CDS             3954..5234
                     /locus_tag="VYO94_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1759264.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5238..5858
                     /locus_tag="VYO94_000594"
     CDS             5238..5858
                     /locus_tag="VYO94_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1759265.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKNLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLDPEKTY
                     YIGDRTLDVEFAKNSGIQSINFLESSFEGNHRIQALADIPHIFESK"
     gene            6024..7166
                     /locus_tag="VYO94_000595"
     CDS             6024..7166
                     /locus_tag="VYO94_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1759266.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVFWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVALSTDSTTPEGQPAETTSPVAEATPQETTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVTKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7680..8018
                     /locus_tag="VYO94_000596"
     CDS             7680..8018
                     /locus_tag="VYO94_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1759267.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQWEVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            8038..8406
                     /locus_tag="VYO94_000597"
     CDS             8038..8406
                     /locus_tag="VYO94_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV1759268.1"
                     /translation="MTIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            8513..9157
                     /gene="pcp"
                     /locus_tag="VYO94_000598"
     CDS             8513..9157
                     /gene="pcp"
                     /locus_tag="VYO94_000598"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1759269.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVAINQDDARTSDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFSYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(9185..10042)
                     /locus_tag="VYO94_000599"
     CDS             complement(9185..10042)
                     /locus_tag="VYO94_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV1759270.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10172..11314
                     /gene="tgt"
                     /locus_tag="VYO94_000600"
     CDS             10172..11314
                     /gene="tgt"
                     /locus_tag="VYO94_000600"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV1759271.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11415..13232
                     /locus_tag="VYO94_000601"
     CDS             11415..13232
                     /locus_tag="VYO94_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1759272.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13385..14536
                     /gene="nagA"
                     /locus_tag="VYO94_000602"
     CDS             13385..14536
                     /gene="nagA"
                     /locus_tag="VYO94_000602"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV1759273.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14699..15757
                     /locus_tag="VYO94_000603"
     CDS             14699..15757
                     /locus_tag="VYO94_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1759274.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15908..16273
                     /locus_tag="VYO94_000604"
     CDS             15908..16273
                     /locus_tag="VYO94_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV1759275.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16349..17290
                     /locus_tag="VYO94_000605"
     CDS             16349..17290
                     /locus_tag="VYO94_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV1759276.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEEFAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17238..18254
                     /locus_tag="VYO94_000606"
     CDS             17238..18254
                     /locus_tag="VYO94_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV1759277.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVRTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18256..18579
                     /gene="comGC"
                     /locus_tag="VYO94_000607"
     CDS             18256..18579
                     /gene="comGC"
                     /locus_tag="VYO94_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV1759278.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQDDGRITEEQAKAYKEYHDKQNTS
                     QIVKD"
     gene            18542..18976
                     /locus_tag="VYO94_000608"
     CDS             18542..18976
                     /locus_tag="VYO94_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV1759279.1"
                     /translation="MINKILVKSLKIKAFTILESLLVLGLVSILALGLSGSVQSTFAA
                     VEEQIFFMEFEELYRETQKRSVASQQKTSLNSDGQTISNGSQKLPVPKGIQAPSDQSI
                     TFDRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18981..19241
                     /locus_tag="VYO94_000609"
     CDS             18981..19241
                     /locus_tag="VYO94_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759280.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19204..19665
                     /locus_tag="VYO94_000610"
     CDS             19204..19665
                     /locus_tag="VYO94_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1759281.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLIALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRFYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19643..20056
                     /locus_tag="VYO94_000611"
     CDS             19643..20056
                     /locus_tag="VYO94_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1759282.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTRVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20193..20787
                     /locus_tag="VYO94_000612"
                     /pseudo
     CDS             20193..20787
                     /locus_tag="VYO94_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20848..21801
                     /locus_tag="VYO94_000613"
     CDS             20848..21801
                     /locus_tag="VYO94_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1759283.1"
                     /translation="MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21852..23042
                     /locus_tag="VYO94_000614"
     CDS             21852..23042
                     /locus_tag="VYO94_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV1759284.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23191..23562
                     /gene="rnpA"
                     /locus_tag="VYO94_000615"
     CDS             23191..23562
                     /gene="rnpA"
                     /locus_tag="VYO94_000615"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV1759285.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23537..24361
                     /locus_tag="VYO94_000616"
     CDS             23537..24361
                     /locus_tag="VYO94_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1759286.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24380..25366
                     /locus_tag="VYO94_000617"
     CDS             24380..25366
                     /locus_tag="VYO94_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV1759287.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25417..26040
                     /locus_tag="VYO94_000618"
     CDS             25417..26040
                     /locus_tag="VYO94_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV1759288.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLEKQAKILDIPTVKGIYYLAYSDGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26171..27628
                     /locus_tag="VYO94_000619"
     CDS             26171..27628
                     /locus_tag="VYO94_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1759289.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27651..27932
                     /locus_tag="VYO94_000620"
     CDS             27651..27932
                     /locus_tag="VYO94_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1759290.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            28008..28493
                     /locus_tag="VYO94_000621"
     CDS             28008..28493
                     /locus_tag="VYO94_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1759291.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28510..29175
                     /locus_tag="VYO94_000622"
     CDS             28510..29175
                     /locus_tag="VYO94_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV1759292.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKNEIKR
                     IWG"
     gene            29179..30042
                     /locus_tag="VYO94_000623"
     CDS             29179..30042
                     /locus_tag="VYO94_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV1759293.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYGTGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            30044..30748
                     /locus_tag="VYO94_000624"
     CDS             30044..30748
                     /locus_tag="VYO94_000624"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV1759294.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVEPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30925..32598
                     /locus_tag="VYO94_000625"
     CDS             30925..32598
                     /locus_tag="VYO94_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1759295.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            32710..33801
                     /gene="ulaG"
                     /locus_tag="VYO94_000626"
     CDS             32710..33801
                     /gene="ulaG"
                     /locus_tag="VYO94_000626"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV1759296.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33915..35891
                     /gene="tkt"
                     /locus_tag="VYO94_000627"
     CDS             33915..35891
                     /gene="tkt"
                     /locus_tag="VYO94_000627"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1759297.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMNEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEVHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            36008..36307
                     /gene="yajC"
                     /locus_tag="VYO94_000628"
     CDS             36008..36307
                     /gene="yajC"
                     /locus_tag="VYO94_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1759298.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36354..36782
                     /locus_tag="VYO94_000629"
     CDS             36354..36782
                     /locus_tag="VYO94_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV1759299.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLCQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36784..37194
                     /locus_tag="VYO94_000630"
     CDS             36784..37194
                     /locus_tag="VYO94_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759300.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37494..40145
                     /gene="adhE"
                     /locus_tag="VYO94_000631"
                     /gene_synonym="adhC"
     CDS             37494..40145
                     /gene="adhE"
                     /locus_tag="VYO94_000631"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV1759301.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12233 a         7234 c         9113 g        11822 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaaac tattttggag gattacccaa gtccggctga agggaacggt
      301 cttgaaaacc gtcaggcgtg taaaagcgtg cgtgggttcg aatcccacat cctcctttta
      361 tattattaac gcgggatgga gcagctcggt agctcgtcgg gctcataacc cgaaggtcgt
      421 aggttcaaat cctgctcccg caataaggct cggtagctca gttggtagag caatggattg
      481 aagctccatg tgtcggcggt tcgattccgt ctcgcgccat ttatatattt tggaagggta
      541 gcgaagaggc taaacgcggc ggactgtaaa tccgctcctt cgggttcggg ggttcgaatc
      601 cctccccttc cattttacgg gcatagttta aaggtagaac taaggtctcc aaaaccttca
      661 gtgtgggttc aattcctact gcccgtgtta atagaattat ggcgggtgtg gtgaagtggt
      721 taacacacca gattgtggct ctggcatgcg tgggttcgat ccccatcact cgcctatttt
      781 atattggggt atagccaagc ggtaaggcaa gggactttga ctccctcatg cgttggttcg
      841 aatccagcta ccccagttac tatttgccgg cgtggcggaa ttggcagacg cgctggactc
      901 aaaatccagt gtccgcaagg acgtgccggt tcgaccccgg ccgccggtat agtatagtgt
      961 taggaacgtt gttattcttc gttccttttt tatattattt ttggtataat tatagttatt
     1021 caaattttat ttagattaag aaagtgtagg ggagtatgtc ttgttctatc gatttattaa
     1081 aacatcggta tttgaaaaat attaaagaaa atcctgaatt gtttgtcgga attgagttgg
     1141 agtatcctgt tgcaagttta gaaggggatg ctacagatgt tgaagttata aaggatctat
     1201 ttcattattt agtttctact ttggatctca ccgtagcaaa ggtagatgat tttggcaatc
     1261 tgatccagtt agtagatccg ataagtcagg atgctatttt atttgaagtt tcctatacaa
     1321 cgattgagtt tgcatttggt aaggctgaaa cgattcaaga ggtcgaaaat cgtttcaata
     1381 attatatgaa tgtaattcag agaaagttag ctgaatcaaa tcatgctatt gttggctgtg
     1441 gtatccatcc caactgggat aaaaatgaga attgtccagt ggcttatcca cgctatcaga
     1501 tgttgatgga ttatttgaat ttgagtagaa atattattaa atcagattta catcatttcc
     1561 ctgaatatgg tacttttatc tgtgggagcc aggttcagct ggatatttca aaaaccaact
     1621 acttacgggt gattaatgct tttactcaaa ttgaagcggc taaggcttat ttatttgcaa
     1681 actctgagtt ttcgggtgcg gattgggata cgaaaatttc aagggatatt ttctgggaag
     1741 aatctatgca tggtatctat ccagagaatg ttggggtcaa tgctagactc cttaatgatg
     1801 aagctgattt ttttgactat ctaaatcatt ctgcgatttt tactgcggaa cgtgatgggc
     1861 agacctatta tttttatcct attcaggctg gggactattt ggctacgcct gaaatccaag
     1921 catttgctct gaatggggat gaggttatta tttcccccca agagaaggat tttgaaactc
     1981 atcgtagtta ccagtaccaa gacttaacga ctcgaggaac agttgagttt cgtagtgtgt
     2041 gtacacagcc acttgatagg acttttgctt ctgcagcttt tcacttggga ttattggtta
     2101 atttagacaa gttagaagct tacttagaaa cagcaccttt ctttaaagta tttggttatg
     2161 attacaagtc tttaaggaga caattttcta agaaaaatct tacagatgag gaagaaacta
     2221 cgattattga attttccaaa gacttactcc tactagctga ggagggacta gtggtgagaa
     2281 ataaggaaga aatgacctat ttacagcctt tgagagaaga attgagccta taatttctct
     2341 tataaaggga gaattttctg aaaaatcatg atataatgga cgagactata gataaaggat
     2401 agagagtaat gacattagtt tatcaatcaa cgcgtgatgc caacaataca gtaactgcca
     2461 gccaagcaat tttgcaaggt ttggcgacgg acggcggttt gtttacaccg gttacttatc
     2521 caaaggtaga tttgaacttt aacaaattga aagatgcttc ttaccaggaa gttgctaagc
     2581 tagttttgtc agcattttta gatgacttta cagctgagga gttggactac tgtatcaaca
     2641 atgcctacga tagcaaattt gatactccag ctattgcacc attagtgaaa ttagatgggc
     2701 aatacaattt ggaacttttc catggttcaa cgattgcctt taaggatatg gccttgtcta
     2761 ttttgccata ctttatgacg actgctgcta agaaacatgg tttggagaac aagattgtta
     2821 tcttgacagc gacatctggt gacacgggga aagctgctat ggcggggttt gcggatgtgc
     2881 ctggtactga gattatcgtc ttttatccaa agggtggtgt cagcaaggta caagagttgc
     2941 aaatgaccac tcagaatggt gacaatactc atgttatcgc tatagatggt aactttgacg
     3001 atgcgcaaac caacgtgaag cacatgttta acgacgtggc tcttcgtgaa agattagcgg
     3061 ccaacaagtt gcaattttca tctgctaact ctatgaatat cggtcgtttg gtgccacaga
     3121 ttgtttatta tgtttatgcc tatgctcagt tggtcaagac tggtgagatc gtggctggtg
     3181 ataagattaa cttcacagta ccaacaggaa actttggaaa tatcttggct gccttttatg
     3241 ccaaacaaat cggtctccca gttggtaaat tgatctgtgc ttcaaatgac aacaatgttt
     3301 tgacagactt ctttaaaaca cgtgtctatg acaaaaaacg tgagtttaag gtaacaacca
     3361 gcccatctat ggatatcttg gtatcttcaa acttggagcg cttgattttc catcttttgg
     3421 gaaataatgc tgaaaagaca gctgaactca tgaatgcttt gaacatgcaa ggacaatata
     3481 agttgataga ctttgatgca gagattttgg acctctttgc agctgaatat gcgactgagg
     3541 aagaaacagc ggcagaaatc aagcgtgttt atgagtcaga ttcttatatt gaggatccac
     3601 atacggcggt tgcctcagca gtttatagaa aataccaagc ggttactgat gatgcgacta
     3661 agacagtgat tgcttcaaca gctagtccct acaagttccc agtagttgca gtagaagctg
     3721 taactggaaa agcaggttta acagactttg aagccttggc tcaattacat gaaatctcag
     3781 gcgttgcagt gccaccagca gttgatgggc ttgaaatagc tccaattcgt cacaagacaa
     3841 cagtggcagc tgctgacatg caagcagcgg ttgaggctta tttaggactt taagacagag
     3901 ggagcaaact cggttgggaa actaactgag tttcttttca tcaggaggag agattgttta
     3961 agaaaaataa agacattctt aatattgcat tgccagctat gggtgaaaac tttttgcaga
     4021 tgctaatggg aatggtggac agttatttgg ttgctcattt aggattgata gctatttcag
     4081 gggtttcagt agctggtaat attatcacca tttatcaggc gattttcatc gctctgggag
     4141 ctgctatttc cagtgttatt tcaaaaagca tagggcagaa agaccagtcg aagttggcct
     4201 atcatgtgac tgaggcgttg aagattacct tactattaag tttcctttta ggatttttgt
     4261 ccatcttcgc tgggaaagag atgataggac ttttggggac ggagagggat gtagctgaga
     4321 gtggtggact gtatctatct ttggtaggcg gatcgattgt tctcttaggt ttaatgacta
     4381 gtttgggagc cttgattcgt gcaacgcata atccacgtct gcctctctat gttagttttt
     4441 tatccaatgc cttgaatatt cttttttcaa gtctagctat ttttgttctg gatatgggga
     4501 tagctggtgt tgcttggggg acaattctgt ctcgtttggt tggtcttgtg attttgtggt
     4561 cacaattaaa actgccttat gggaagctaa cttttggttt agataaggaa ctgttgacct
     4621 tggctttacc agcagctgga gagcgactta tgatgagggc tggagatgta gtgatcattg
     4681 ccttggtcgt ttcttttggg acggaggcag ttgctgggaa tgcaatcgga gaagtcttga
     4741 cccagtttaa ctatatgcct gcctttggtg tcgctacggc aacggtcatg ctgttggccc
     4801 gagcagttgg agaggatgat tggaaaagag ttgctagttt gagtaaacaa accttttggc
     4861 tttctctgtt cctcatgttg cccctgtcct ttagtatata tgtcttgggt gtaccattaa
     4921 ctcatctcta tacgactgat tctctagcgg tggaggctag tgttctagtg acactgtttt
     4981 cactacttgg gacccctatg acgacaggaa cagtcatcta tacggcagtc tggcagggat
     5041 taggaaatgc acgcctccct ttttatgcga caagtatagg catgtggtgt atccgcattg
     5101 ggacaggata tctgatgggg attgtgcttg gttggggctt gcctggtatt tgggcagggt
     5161 ctctcttgga taatggtttt cgctggttat ttctacgcta tcgttaccag cgctatatga
     5221 gcttgaaagg ataggaaatg caaaaaacag cttttatttg ggatttagac gggactttat
     5281 tggactctta cgaagcgatt ttatcaggga ttgaggagac ttttgctcag ttttctattc
     5341 cttatgataa ggagaaggtg agagagttta tcttcaagta ttcggtgcaa gatttgcttg
     5401 tgcgggtggc agaagataga aatctggatg ttgaggtgct aaatcaggtg cgtgcccaga
     5461 gtctggctga gaagaatgct caggtagttt tgatgccagg tgcgcgtgag gtgctagctt
     5521 gggcagacga atcaggaatt cagcagttta tatatactca taaggggaac aacgctttta
     5581 ccattctcaa gaacttgggg gtggaatcct attttacaga gattttaacc agtcagagtg
     5641 gctttgtgcg gaagccaagt ccagaagcgg ctacctatct gctagataag tatcagctgg
     5701 atcctgagaa gacctattat ataggggacc ggactttaga tgtggaattt gccaagaata
     5761 gcggtattca aagcatcaac tttttagaat cttcttttga aggcaatcac aggattcaag
     5821 cactagcaga tattcctcat atttttgaga gtaagtaacg agaagattgt gtcagttttg
     5881 tgacagaaac ctaacaaact atttcaagta atcgagtttg ttacaaggaa tagacagttc
     5941 tgttaaatag gcccgagagg gctttttttc tacatttttt gtgttatcat agacaggtac
     6001 tcatttgaaa ggaatttgaa agaatgaaga aaagaatgtt attagcgtca acagtggcct
     6061 tgtcatttgc cccagtattg gcaactcaag cagaagaagt tttttggact gcacgtagtg
     6121 ttgagcaaat ccaaaacgat ttgactaaaa cagacaacaa aacaagttat acagtacagt
     6181 atggtgatac tttgagcacc attgcagaag ccttgggtgt agatgtcaca gtgcttgcga
     6241 atctgaacaa aatcactaat atggacttga ttttcccaga aactgttttg acaacgactg
     6301 tcaatgaagc agaagaagta acggaagttg aaatccaaac acctcaagca gattctagtg
     6361 aagaagtgac aactgcgaca gcagatttga caaccaatca agtgaccgtt gatgatcaaa
     6421 ctgttcaagt tgcagatctt tctcaaccaa ttgcagaagc tccaaaagaa gtagcatcaa
     6481 attcagaagt tgcagagaca gtgactgctg cagaagaagt ggcactatct acagactcta
     6541 ctacgccaga gggacaacca gccgaaacaa ctagtccagt tgcagaagca actcctcagg
     6601 aaacgactcc agctgagaag caggaaacac aagcaagccc tcaagctgca tcagcagtgg
     6661 aagcaactac aacaagttca gaagcaaaag aagtagcatc atcaaatgga gctacagcag
     6721 cagtttctac ttatcaacca gaagagacga aaataatttc aacaacttac gaggctccag
     6781 ctgcgcccga ttatgctgga cttgcagtaa caaaatctga aaatgcaggt cttcaaccac
     6841 aaacagctgc ctttaaagaa gaaattgcta acttgtttgg cattacatcc tttagtggtt
     6901 atcgtccagg agacagtgga gatcacggaa aaggtttggc tatcgatttt atggtaccag
     6961 aacgttcaga attaggggat aagattgcgg aatatgctat tcaaaatatg gccagccgtg
     7021 gcattagtta catcatctgg aaacaacgtt tctatgctcc attcgatagc aaatatgggc
     7081 cagctaacac ttggaatcca atgccagacc gtggtagtgt gacagaaaat cactatgacc
     7141 acgttcacgt ttcaatgaat ggataaaccc gacttggtaa catcattttg acgaatgaga
     7201 tctagctttc gtgataggaa gcgattctcg ttcgtttttt ctttgtcata ctcttcgaaa
     7261 atctcttcaa acaacgtcag ttttatctga aacctcaaag ctgtgctttg agcaacctgc
     7321 gactagcttc ctagtttgct ttttgatttt cattgagtat caatttgaat ggaaaatgga
     7381 aagttatcat cttgtaatga gttaagcaac attcttgcaa tctattttat agtagattga
     7441 aactagaata gtacacaact gcttctaaaa cattgttaga aatcgatttg actgtcctga
     7501 tcgatttgtc ctgctcttat ttcatttcac tatactttat attataattg actggtcaaa
     7561 tattgataaa tcaataaaaa gagaggggaa gaaatgctag agattcaaga tttactgtat
     7621 caactccgct tgtctgagca agcgagtacg caattgtttg aaaaaggctt gggattagtt
     7681 tgacacggta tcagatttta ctgtttttgc tggagcattc tccttgtaac caaatggcgg
     7741 ttcaggagcg tttgaaaatt gatcaggctg ctttgacacg gcatttcaag attttggaaa
     7801 cggaaggttt ggtggagcgt catcgtaatc ctgaaaatca gtgggaagtg ttggtagagg
     7861 ctgcgaagta tgccaaggag cagttagtgg tgaatccccc tctgcaacat atcaaggtta
     7921 aggaagagat ggaaagtatc ttaacagagt ttgagagaac agaactcagc cgtttattaa
     7981 ataaattggt tttgggtatt gaaaatatag aaatttaagg agaaatagat gtcaattatt
     8041 acaattatta caattatttt aacaacgatc gttgctttgg agcattttta cattttttat
     8101 ttggaaagta ttgccacgca atcagatgcg actagtcgtg tatttaatat ggaaaaggaa
     8161 gaattggctc atccgtcagt aagttcattg ttcaaaaatc aagggattta taaggctctg
     8221 ctaggagtct ttctctggta tggcatttat ttctcacaga atttagaaat tgtgactatt
     8281 tttgtcttat ttgtgattgg tgctgcgact tacggctctt taacagcgga taaaaaaatt
     8341 attttgaaac aaggtggatc agctattttg gccttgatta gtattttact ctttaaatac
     8401 acttgaaggt cgattctaat ctcgctaatc ctttttaatc cagaataagg gaaatatgtt
     8461 atacttgttt ttaagaaaaa agtctcattg aattggtttt gaggagttag aaatgaaagt
     8521 attagtgaca ggttttgagc cctttggagg ggaaaagggc aatccagctt tggaggccat
     8581 taaaggttta ccagctgaaa tccatggtgc tgaggtccgt tggctagagg tgccgacagt
     8641 ttttcacaaa tctgctcaag tattggaaga agagatgaat cgttatcaac ctgactttgt
     8701 cctttgtatt gggcaagctg gtggaagaac tagtttgaca cctgaacgag tggccattaa
     8761 tcaagacgat gcacgtactt ctgataacga agataatcaa ccgattgacc gtcccattcg
     8821 cccagatggt gcttcggcct actttagtag tttgccgatt aaagcgatgg ttcaagctat
     8881 aaaaaaagag ggcttaccgg cctctgtttc caatacggca gggacttttg tctgcagcca
     8941 tttgatgtat caggctctct atttggtaga aaagaaattt tcatatgtta aggcaggttt
     9001 tatgcatatt ccttatatga tggaacaggt ggtgaacaga ccgactactc cagctatgag
     9061 tttagtggat attcggcgag ggatagaagc agcaatcggc gctatgatag aacatggaga
     9121 tcaggaactc aagttggtag gcggagaaac tcattgatag aaaaaagctt gaggggaaaa
     9181 accttcaagc ttttggacgt tttcgagcca atactgctcg gtaaaacata attttagtgc
     9241 attggatata aggtaggagt gaaaaactag caatgccaaa ggtaatccaa ttgaggaagt
     9301 accaaggaag aagctgtaaa tctaggacaa agtgctggaa cttgtagccc ttcataaagg
     9361 aacggctagt ttttaggatt cgtcttggtg ggacctgtcc taggtctaga ctataacaga
     9421 gaagaaattc cacctgtgaa taggcataat actgtggaat atagaggata tttcctacaa
     9481 tgatcaagat gagacttgca agaaagtaga gtccaaagac catgaggaaa cgctcggttt
     9541 caactgatga gagatctaga tttggaaact caggatgtag ggtgacgaat tttttggcta
     9601 aaaagctact ataaaagagg aggtaaatcc caagtaaatt agggatactc cataaaaaga
     9661 gatagaaacg tttgagaagt agggtcaaaa aggtttgaga aaagcgctcc tcatcaaaga
     9721 gagctaggct gttttttaca gatggctccg ttttagaatc tttcatgagt gtcagtgttg
     9781 catagacgga actggtcaaa agaatagtcc cgataaagga gactagtaga ggaaagaggt
     9841 aggcttgaag tatttggcca agtatgctga aaaatggctg ttctaaaaca gtcccgtgga
     9901 tccgagataa gggattaaga aaactagata agatgaccag catactggga aggatataga
     9961 ggagaaagag acggggggtg tcagcctgaa aatgttttga ctcctgacga attgttttta
    10021 aatcaatttt tggatagttc attctcttat tataccatag ttcttataca tagttcgtga
    10081 cagttcctac tttttttgat aaaatcatac agtgtgtcct tgggcacact gtatgaactg
    10141 ggactgtctt tcccagcttc ggaggtaaaa aatgtcagat tcaccaatca aatatcgttt
    10201 gattaagaaa gaaaaacaca caggagctcg tctaggagaa atcatcactc cccacggtac
    10261 ctttccgaca cctatgttta tgccagttgg gacacaagcc actgtcaaaa ctcagtcacc
    10321 tgaagaattg aaggagatgg gttcgggaat tatcctatca aacacctatc atctctggct
    10381 tcgccctgga gatgaactca ttgcacgcgc tggtggtctc cacaagttca tgaattggga
    10441 ccagcctatc ttgacagata gtggtggttt tcaggtttat tctttagcag atagccgtaa
    10501 tatcacagaa gaaggagtaa cctttaaaaa tcatctaaat ggttctaaga tgttcctatc
    10561 cccagaaaaa gccatctcta ttcagaataa tctgggttca gacatcatga tgtcctttga
    10621 tgaatgtcct cagttttatc aaccttatga ctacgttaag aaatcgatcg agcgtaccag
    10681 ccgttgggct gagcgtggtt tgaaggctca ccgtcgtcca catgaccaag gtttgtttgg
    10741 aattgtgcaa ggtgcaggat ttgaagacct tcgccgccaa tcagctcatg atcttgtcag
    10801 catggatttc tcaggctact ctatcggtgg tttggcagtg ggagaaaccc atgaagagat
    10861 gaatgcggtc ttggacttta caactcaact gctacctgaa aataaacctc gttatctgat
    10921 gggtgtggga gcgccagata gcttgatcga tggggtcatt cgtggggtgg atatgtttga
    10981 ctgtgtctta ccgactcgaa ttgctcgtaa cgggacttgt atgaccagtc aaggacgttt
    11041 ggttgtgaaa aatgcccagt ttgctgagga ctttacgcca ctggatcctg agtgtgattg
    11101 ttacacatgt aataactata cacgcgctta ccttcgtcac ctgctcaagg ctgatgaaac
    11161 ctttggtatc cgcttgacta gctaccacaa tctttacttc ttgcttaact tgatgaagca
    11221 agtgcgacaa gccatcatgg atgacaatct cttggaattc cgtgagtatt ttgtggaaaa
    11281 atatggctat aataagtcag gacgtaattt ctaaaatgga attgatataa gctaaaaatc
    11341 ctaagttttc tcttaggatt tttcttcttt ttttgataga ataaagtgta caatgaaagg
    11401 aagaataaac tcgtatgcgc attaaatggt tttccttgat taggattata ggtttacttt
    11461 tggtactctt gtatcacttc tttcagacga tctttcctgg aggatttttc ggggtagatg
    11521 tctttttcac attttcaggt ttcctgatta cagctctact cattgaagaa ttttctaaga
    11581 acaatgagat tgatttgata ggatttttta gaagacgctt ttatcggatt gtgccacctg
    11641 tggttttgat ggtcttggtg accatgcctt ttactttctt ggttcgccaa gactatgttg
    11701 ctggaattgg tggccagatt gcgggcgtct taggctttat gaccaacttc tatgaactcc
    11761 taacaggtgg gagttatgaa tctcagttca ttcctcattt gtttgttcat aattggagtt
    11821 tggcagttga ggttcactac tatattcttt ggggattggc agtttggttc ttatccaaac
    11881 aagctaaatc aaatggtcag ttgaagggga tggtctttct cttatctgct gttgccttct
    11941 tgatcagttt cttctccatg tttattggta gttttctagt gacctcttat tcctctgttt
    12001 atttctccag tttaactcat gtctatccat tctttttggg aagtatgtta gcaactattg
    12061 taggtgttcg tcagacgact tccctcgtca agcagttgga taaaatctgg gatttacgaa
    12121 agactttggt agtttttgga ggaggctttg gtttcctagt tcttttgact ttctttgtca
    12181 aattcactta tctttttgcc tatcttatcg gcttcttgct tgccagtctt gcagctcttg
    12241 ccatgattct ggcggcgcgt gtcttacatg aaaagacaca tcatatacag gagccgaaga
    12301 ttatcagctt tttagcggat actagctatg cggtttatct tttccattgg cctttctata
    12361 tcattttctc acagttgaca tcaaatcttc ttgctgtatt actgactctg atttgttctt
    12421 atggctttgc cagtctgtca ttttatgtat tggaaccttg gattgcaggc aagaacacac
    12481 ctattttaca aactcttcgt cccctgcctt atattcacgc aattcttgca gcaggtacag
    12541 gaatcttgac cttcattgtc tgcatggtga ccttgttggc accacaagtg ggagcgtttg
    12601 agacagactt gactgtcaat ggcttgaagc aagctgcaac aaatattggc cagaccaagg
    12661 tgatggcaga acgggcagat gcaaacagtt tgggaattgc tgatggcact atgttaattg
    12721 gtgactcagt ggctttaagg gcaaatacag cactacagac agctcttcct ggagcacaga
    12781 ttaacgcgca ggtcagcgta acaaccaaga ccgcaaatga aatcatgcta aataatagcc
    12841 agaataaatt tttacctaag acggtggtca ttgcgactgg ggtaaataat cctgagaatt
    12901 acaaggatga ctgggacagt atcgtgaaaa atcttcctaa gggacaccat atgattttgg
    12961 tgactcctta tgagggagat aagacaaaag agacctatgc catcgttgag aaggctgctg
    13021 cctatatgag agaattggca gagaagacac cttacattac gatagcagat tggaatcaag
    13081 ttgcgaaaga gcatccagaa atttgggcag gaacagacca ggttcatttc gggagtgaga
    13141 gtagcactat cgaagcagga gcaaaattgt atgcagatac gattgccaca gctttgcaga
    13201 cagctcaaga caagccggtt aaatcaaaat aacttgtatt aaaaaagaga agagttggag
    13261 aaatccagct cttttaaaat atctccaaaa aataggtcta taccatttac aaataaaaaa
    13321 gaaaggttta taatgtaatt gacataataa attgtagaat caatctttta aggaggttaa
    13381 cattatgcct aactatatta aagcggatca gtttttctac ccacacggag ttcgtcgagg
    13441 tggttacttg gaacttgtgg acggcaagtt tgggaaacat gtagagcaga ttcctgaagg
    13501 ggctgaggtg attgactata caggttatag cattgcccca ggtcttgtgg atactcatat
    13561 tcatggatat gcaggtgtag atgtgatgga caacaacatt gaaggtacat tgcatactat
    13621 gagtgaagga cttcttagta ccggtgttac cagtttctta cccacaactt taacagccac
    13681 ttatgagcaa ttgcttgcag tcactgaaaa tcttggaaac cattataaag aagcaacagg
    13741 tgctaagatt cgtgggattt attatgaagg tccatatttc acagaaactt ttaagggggc
    13801 acaaaatcca acttatatga gagacccggg tgttgaggag tttcattctt ggcaaaaagc
    13861 ggcaaatggc ttgcttaata aaattgccct tgcaccagaa cgtgatgggg tggaagactt
    13921 tgttcgtaca gttacgggcg aaggtgtgac ggttgctctt ggacattcaa acgcgacttt
    13981 tgatgaagcc aaaaaagcag tcgatgctgg agcgagtgtt tgggtgcatg cctacaatgg
    14041 aatgcgtggg ttgactcacc gtgaattggg tatggttgga gccatgtacc aattgccaca
    14101 tacctatgca gagttgatct gtgatggtca ccacgtagat ccaaaggctt gcgaaattct
    14161 tatcaaacaa aaaggaacag aaaacatcgc tcttatcaca gactgtatga cagctggggg
    14221 attggaagac ggagattata tgttgggaga attcccagtt gtcgttgcaa atggaactgc
    14281 acgcctcaaa tcgacaggta acttggcagg ttctatcctc aaactcaaag atggtttgaa
    14341 gaatgtggtc gaatggggaa ttgcgaatcc gcatgaagca gtcatgatgg ccagcttcaa
    14401 cccagctaaa tccgttcaca tcgatgacgt ctgtggccaa atccgtgaag gctacgacgc
    14461 tgacttcatc gtattagata aagatttgga attggtagca acctacctag atggcgtaaa
    14521 acgttatcaa gcataagaga gaaagcagaa gttagagact aacttctgct tttttatgca
    14581 gggtacttta ctggtaaata aaaagttaaa aaaatcacaa aaaaagcttg aagaaacaaa
    14641 gaaaaaggct tacaattgaa ctataaatat tacaaataaa aaaacggagg agtgctttat
    14701 gaaagcctat acttatgtta aaccaggact tgcttctttt gttgatgtag acaaaccagt
    14761 tattcgcaag ccaacagatg ctattgtgcg tattgtaaaa accactattt gtggaacaga
    14821 cctccatatt atcaaagggg atgttcctac ttgccaaagt ggtaccattc ttggccacga
    14881 agggattggg attgttgaag aagttgggga aggagtttcc aacttcaaaa aaggtgacaa
    14941 ggtcttgatt tcttgcgtct gtgcctgtgg taaatgctac tactgtaaaa aaggaattta
    15001 tgctcactgt gaagacgaag ggggctggat tttcggtcac ttgattgatg gtatgcaggc
    15061 tgaatatcta cgtgtccctc atgcagataa tactctttac catactccag aagacttgtc
    15121 agatgaagct ttggttatgc tgtcagacat tctgcctact ggatatgaaa ttggtgtctt
    15181 aaaagggaaa gtagaacctg gttgcagcgt agccattatt ggttcaggtc cagttggatt
    15241 ggctgctctt ttaacagccc aattctattc accagctaaa ttgattatgg tagacctaga
    15301 cgataaccgc ttggaaactg ccctatcatt cggtgcgact cataaggtta attcttcaga
    15361 ccctgaaaaa gccattaaag aaatttatga tttgacagat ggtcgtggtg tggatgtcgc
    15421 tatcgaagct gttggtattc ctgcaacatt tgatttctgt caaaagatta tcggtgtaga
    15481 cggaacggtt gccaactgtg gtgtgcatgg taaaccagtt gaattcgatt tagataaact
    15541 ttggattcgc aacatcaatg taacaactgg tttggtatct acaaatacga ctccacaatt
    15601 gttgaaagca cttgaaagtc ataagattga accagaaaaa ttggtaactc actatttcaa
    15661 actcagtgaa attgaaaaag cctatgaagt cttcagtaag gcagcagacc accatgccat
    15721 taaggtcatt atcgaaaacg atatctcaga agcctaagta gtaaaaatat ttttgtacat
    15781 aagtaaatag aaattcagtc atccatcaga tggctggatt ttttatcaaa aaattaagaa
    15841 atgagcatat ttctttcctt gtctggcgga attggttata atatacggta caaaggaatg
    15901 aatgaatatg tatcgtgtta tagaaatgta cggagatttt gaaccgtggt ggttcttaga
    15961 aggttgggaa gaagatattg tagcaagtag aaaatttgac cagtattatg atgctctcaa
    16021 atactacaaa acttgctggt ttagattgga acaagaatcc cctctttata aaagtagaag
    16081 cgacttgatg accatttttt gggacccgga agaccaacgc tggtgtgatg aatgtgatga
    16141 gtatttacaa caataccatt ctttggctct tttgcaggat gagcaggtta tcccagacga
    16201 aaaactacgc tcaggctatg aaaaacaaac cagtcaggaa aggaatcgtt cttgccgtat
    16261 gaaattaaaa tagagaaaag taactttttt ggagttgctt tttttatttt tctaacgctt
    16321 tgcgaatagt ataggtgagg aggtaagtat ggttcaagaa attgcacaag aaatcattcg
    16381 ttcggctcgg aaaaaagggg cgcaagacat ttattttgtc cctaagttag atgcctatga
    16441 gcttcatatg agggtaggag acgagcgctg taaaattggt agctatgatt ttgaaaagtt
    16501 tgcagccgtt atcagtcact ttaagtttgt ggcgggtatg aatgtgggag aaaaaagacg
    16561 tagtcaactg ggttcctgtg attatgccta tgaccagaag atagcgtctc tacgtttatc
    16621 tactgtaggc gattatcggg ggcatgagag tttggttatc cgtttgttgc acgatgagga
    16681 gcaggacttg catttttggt ttcaggatat tgaagaatta ggcaagcagt acaggcaacg
    16741 gggactctat ctttttgctg gtccggttgg gagtggtaag acgaccttga tgcatgaatt
    16801 gtccaagtca ctctttaaag gacagcaagt tatgtccatc gaagatcctg tcgaaatcaa
    16861 gcaggacgac atgcttcagt tgcagttgaa cgaagcaatc ggcctaacct atgaaaatct
    16921 aatcaaactt tccttgcgtc atcgaccaga tctcttgatt atcggagaaa ttcgtgacag
    16981 cgagacggcg cgtgcagtgg tcagagctag tttgacaggt gcgacagtct tttcaaccat
    17041 tcacgccaag agtatccgag gtgtttatga gcgtctgctg gagttgggtg tgagtgaaga
    17101 agaatttgca gttgttctgc aaggagtctg ctaccagaga ttaatcgggg gaggaggaat
    17161 cgttgacttt gcaagcagag attatcaaga acaccaagca gccaagtgga atgagcaaat
    17221 tgaccagctt cttaaagatg gacatatcac aagtcttcag gctgagacgg aaaaaattag
    17281 ctacagctaa gcaaaaaaat atcatcaccc tatttaacaa tctcttttct agcggttttc
    17341 atctggtgga gaccatctcc tttttagata ggagtgcttt gttggacaag cagtgtgtga
    17401 cccagatgcg tgtgggcttg tctcagggga aatcattctc agaaatgatg gaaagtttgg
    17461 gatgttcaag tgctattgtc actcagttat ccctagctga agtccatggc aatctccacc
    17521 tgagtttggg aaagatagaa gagtatctag acaatctggc caaggtcaag aaaaaattaa
    17581 ttgaagtagc gacctatcct ttgattttgc tgggttttct tctcttaatt atgctggggc
    17641 tacggaatta cctgctccca caactggata gtagcaatat tgccacccga attatcggta
    17701 atctgccaca aatttttcta ggcatggtag ggcttgtttc cgtgcttgcc cttttagcac
    17761 taacttttta taaaagaagt tctaagatga gtgtcttttc tatcttagca cgccttccct
    17821 ttattggaat ctttgtgcgg acctatttga cagcctatta tgcacgtgaa tgggggaata
    17881 tgatttcaca gggaatggag ctgacgcaga tttttcaaat gatgcaggaa caaggttccc
    17941 agctctttaa agaaatcggt caagatctgg ctcaaaccct gaaaaatggc cgtgaatttt
    18001 ctcagacgat aggaacctat cctttcttta ggaaggaatt gagtctcatc atagagtatg
    18061 gggaagttaa gtccaagctg ggtagtgagt tggaaatcta tgctgaaaaa acttgggaag
    18121 ccttttttac ccgagtcaac cgcaccatga atttggtgca gccactggtt tttatttttg
    18181 tggcactgat tatcgtttta ctttatgcgg caatgctcat gcccatgtat caaaatatgg
    18241 aggtaaattt ttaaaatgaa aaaaatgatg acattcttga aaaaagctaa ggttaaagct
    18301 tttacattgg tggaaatgtt ggtggtcttg ctgattatca gcgtgctttt cttgctcttt
    18361 gtacctaatc tgaccaagca aaaagaagca gtcaatgaca aaggaaaagc agctgttgtt
    18421 aaggtggtgg aaagccaggc agaactttat agcttggaaa agaatgaaga tgctagccta
    18481 agaaagttac aagacgatgg acgcatcacg gaagaacagg ctaaagccta taaagaatac
    18541 catgataaac aaaatactag tcaaatcgtt aaagattaag gcctttacca tacttgaaag
    18601 tctcttggtt ttgggtcttg tgagtatcct tgccctgggc ttgtccggct ctgttcagtc
    18661 cacttttgcg gcggtagagg aacagatttt ctttatggag tttgaagaac tctatcggga
    18721 aacccaaaaa cgcagtgtag ccagtcagca aaagactagt ctgaactcag atgggcagac
    18781 gattagcaat ggcagtcaaa agttgccagt ccctaaagga attcaggccc catcagatca
    18841 aagtattaca tttgaccgtg ctgggggcaa ttcgtccctg gctaaggttg aatttcagac
    18901 cagtaaagga gcgattcgct atcaattata tctaggaaat ggaaaaatta aacgcattaa
    18961 ggaaacaaaa aattagggca gtgattttac tggaagcagt agtcgctcta gctatctttg
    19021 ccagcattgc gaccctcctt ttgggacaaa ttcaaaaaaa taggcaagag gaagcaaaaa
    19081 tcttgcaaaa ggaagaagtc ttgagggtag ctaagatggc cttgcagacg gggcaaaatc
    19141 aggtaagcat caacggagtt gagattcagg tattttctag tgaaaaagga ttggaggtct
    19201 accatggttc agaacagttg ttggcaatca aagagccata aggtcaaggc ttttaccttg
    19261 ttagaatccc tgattgccct gattgtcatc agtgggggat tactcctttt tcaagctatg
    19321 agtcagctcc tcatttcaga agttcgctac cagcaacaaa gcgagcaaaa ggagtggctc
    19381 ttgtttgtgg accaacttga ggcagaatta gaccgttcgc agttcgaaaa agtagaaggc
    19441 aatcgtttct atatgaagca agatggcaag gacatcgcca tcggtaagtc aaagtcagac
    19501 gattttcgta aaaccgatgc tagtggacgg gggtatcagc ctatggttta tggcctcaaa
    19561 tcagctcaga ttacagagga caatcaactg gttcattttc gtttccagtt tcaaaaaggc
    19621 ttagaaaggg agttcatcta tcgtgtggaa aaagaagaaa gttaaggcag gtgttctcct
    19681 ctatgcagtc accatggcag ctatctttag tcttttgttg caattttact tgaaccgaca
    19741 agtcgcccac tatcaagact atgctttgaa taaagaaaaa ttggttgctt ttgcaatggc
    19801 taaacgaacc aaggataaag ccgagcaaga aagtggggaa caggtcttta atctaggtca
    19861 ggtaagctat caaaacaaga aaacaagctt ggtgacgagg gttcgtacgt ctaagagcca
    19921 atatgagttt ctgtttcctt cggtcaaaat caaagaagag aaaagagata aaaaggaaga
    19981 ggtagcgact gattcaagcg aaaaagtgga gaagaaaaaa tcagaagaga agcctgaaaa
    20041 gaaagagaat tcatagtcaa ttcaactata atgcgttgaa tccagaatag tccactgtag
    20101 tttctagaaa attgctggaa atggatgtta agctccaatt catttgttta tatcttattt
    20161 cagtttacta tactttgtgc taaattaaag atatgaaaca tgattttaac cacaaagcag
    20221 aaactttcga ttcccctaaa aatatcttcc tcgcaaactt ggtatgtcaa gcagccgaga
    20281 aacagattga tcttctatca gacaaagaaa ttttagattt cggtggtggc acgggtctat
    20341 tagccttgcc cctaacccct agccaagcag gctaagtcag tcactcttgt agacatttct
    20401 gagaaaatgt tggagtaagc tcgtttgaaa gcggagcagc aagcaatcaa gaatatccag
    20461 tttttggagc aagatttacc gaaaaatccc ttggagaaag agtttgattg ccttgctgtt
    20521 agtcgggttc ttcatcatat gcctgatttg gatgcggatc tctcactgtt tcatcaacat
    20581 ttgaaggaag atgggaaact catcattgct gattttacca agacagaagc taatcatcat
    20641 ggatttgatt tagctgaact ggaaaacaag ctaattgagc atggtttttc atctgtgcat
    20701 agtcagattc tctatagcgc tgaagacctg tttcaaggga atcactcaga attcttttta
    20761 acagtatccc aaaaatcact cgcctagtca gggagtgatt tttctataag gatggaaaaa
    20821 agaagggaaa tttgataaga taggaatatg gattttgaaa aaattgaaca agcttatatc
    20881 tatttactag agaatgtcca agtcatccaa agtgatttgg cgaccaactt ttatgacgcc
    20941 ttggtggagc aaaatagcat ctatctggat ggtgaaactg agctaaacca ggtcaaagac
    21001 aacaatcagg cccttaagcg tttagcacta cgcaaagaag aatggctcaa gacctaccag
    21061 tttctcttga tgaaggctgg gcaaacagaa cccttgcagg ccaatcacca gtttacgcca
    21121 gatgctattg ccttactttt ggtatttatt gtggaagagt tgtttacaga ggaggaaatt
    21181 actatcctcg aaatgggttc tgggatggga attctaggcg ctactttctt gacctcgctt
    21241 gataaaaagg tggattactt gggaatggaa gtggatgatt tgctgattga tctggcagct
    21301 agcatggcag atgtaattgg tttgcaggct ggctttgtcc aaggagatgc cgttcgccca
    21361 caaatgctca aagaaagcga tgtggtcatc agtgacttgc ctgttggcta ttatcctgat
    21421 gatgccgttg cgtcgcgcca tcaagttgct tctagccaag aacatactta cgctcatcac
    21481 ttgctcatgg aacaagggtt taagtacctt aagtcagatg gatatgctat ttttctagct
    21541 ccgagtgatt tgttgaccag tcctcaaagt gatttgttga aagtctggtt gaaagaggag
    21601 gcaagtctgg ttgctatgat tagtttacct gaaaatctct ttgctaatgc taaacaatct
    21661 aagactattt ttatcctaca gaagaaaagt gaaatagcag tggagccttt tgtttatcca
    21721 cttgctagct tgcaagatgc aagtgtttta atgaaattta aagaaaattt tcaaaaatgg
    21781 actcaaggta ctgaaatata aaatagattt tgttataata gttgaaaacg cttaaaaagg
    21841 ggtatcatgt tatgacaaaa acaattgcaa tcaatgcagg aagttcaagt ttgaaatggc
    21901 aattatactt aatgccagaa gaaaaagtat tggcgaaagg tttgattgaa cgtatcggtt
    21961 tgaaagattc aatttcaact gtaaaatttg acggccgttc tgaacaacaa attttggata
    22021 ttgaaaatca tatacaagcc gttaaaattt tattggatga cttgattcgt ttcgatatta
    22081 tcaaggctta tgacgagatt acaggtgttg gacatcgtgt tgttgctggt ggagaatatt
    22141 tcaaagaatc aacagttgtt gagggagatg ttttagaaaa agttgaagag ttgagtttgt
    22201 tggctcctct acacaacccg gccaatgcag caggtgttcg tgccttcaag gaattgttgc
    22261 cagacattac cagtgtagtt gtttttgata cttccttcca cacaagtatg ccagagaaag
    22321 cttatcgcta ccctctacca acaaaatatt acacagaaaa caaggttcgt aaatacggtg
    22381 ctcatggtac aagtcaccag tttgtagcag gagaagctgc aaaactcttg ggacgtccat
    22441 tagaagactt gaagttaatt acctgtcata ttggtaacgg aggctcaatt acagctgtga
    22501 aagccggcaa atctgtagac acttctatgg ggttcactcc tcttggtggt attatgatgg
    22561 gaacgcgtac aggggatatt gatccagcta tcattcctta tttaatgcaa tatacagagg
    22621 attttaacac accagaagat atcagtcgtg ttcttaaccg tgaatcaggt cttttgggag
    22681 tttctgctaa ttctagcgat atgcgcgata tagaagcagc tgtagcagaa gggaatcacg
    22741 aggctagctt ggcttatgaa atgtatgttg accgtatcca aaaacatatc ggtcagtacc
    22801 ttgcagtgct aaatggagca gatgccattg ttttcacagc aggtgtcggt gaaaatgcag
    22861 agagtttccg tcgtgatgta atctcaggga tttcgtggtt tggttgtgat gttgatgatg
    22921 aaaagaatgt ctttggcgtt acaggagaca tctcaacaga ggcagctaaa atccgtgtct
    22981 tggttattcc aacagatgaa gaattagtca ttgcccgtga cgttgaacgc ttgaaaaaat
    23041 aagtgaaact aaaaaaatat tcaatacaag gagttgggaa agttattttt ccagcttctt
    23101 tttctgatga aattgtccaa aaccttgcta tgattggctt ttttgaaaaa tatggtataa
    23161 tagtagtaat ttaatagatg gagttgagtt ttgaagaaaa actttcgtgt aaaaagagag
    23221 aaagatttta aggcgatttt caaggagggg acaagttttg ctaatcgcaa atttgtggtc
    23281 taccaattag aaaaccagaa aaaccatttt cgagtaggtc tatcagttag caaaaaactg
    23341 gggaatgccg tcactagaaa tcaaattaag cgacggattc ggcatattat ccagaatgca
    23401 aaagggagtc tggtagaaga tgtcgacttt gttgtcattg ctcgaaaagg agtcgaaacc
    23461 ttgggatacg cagagatgga gaaaaatcta ctccatgtat taaaattatc aaagatttac
    23521 cgggaaggaa atgggagtga aaaagaaact aaagttgact agtttgctag gactgtctct
    23581 gttaatcatg acagcctgtg cgactaatgg ggtaactagc gatattacag ccgaatcggc
    23641 tgatttttgg agtaaattgg tttacttctt tgcggaaatc attcgctttt tatcgtttga
    23701 tattagtatc ggagtgggga ttattctctt tacggtcttg attcgtacag tcctcttgcc
    23761 agtctttcag gtgcaaatgg tggcttctag gaaaatgcag gaagctcagc cacgcattaa
    23821 ggcgcttcga gaacaatatc caggtcgaga tatggaaagc agaaccaaac tagagcagga
    23881 aatgcgtaaa gtatttaaag aaatgggtgt cagacagtca gactctcttt ggccgatttt
    23941 gattcagatg ccggttattt tggccctgtt ccaagcccta tcaagagttg actttttaaa
    24001 gacaggtcat ttcttatgga ttaaccttgg tagtgtggat acaacccttg ttcttccgat
    24061 tttagcagca gtattcacct ttttaagtac ttggttgtcc aacaaagctt tgtctgagcg
    24121 aaatggcgct acgactgcga tgatgtatgg gattccagtc ttgattttta tctttgcagt
    24181 ttatgcgcca ggtggagtcg ccctatattg gacagtgtct aatgcttatc aagtcttgca
    24241 aacctatttc ttgaataatc cattcaagat tatcgcagag cgcgaggccg tagtacaggc
    24301 acaaaaagat ttggaaaata gaaaaagaaa agccaagaaa aaggctcaga aaacgaaata
    24361 aataaggagg aatctggtaa tggtagtatt tacaggttca actgttgaag aagcaatcca
    24421 gaaaggattg aaagaattag atattccaag aatgaaggct catatcaaag tcatttctag
    24481 ggagaaaaaa ggctttcttg gtctatttgg taaaaaacca gcccaagtgg atattgaagc
    24541 gattagtgaa acgactgttg ttaaagcaaa tcaacaggta gtaaaaggcg ttccgaaaaa
    24601 aatcaatgat ttgaacgagc ctgtgaagac ggttagtgaa gaaaccgttg accttggtca
    24661 tgtggttgat gctattaaaa aaatagagga agaaggtcaa ggtatttctg atgaagtcaa
    24721 ggctgaaatc ttaaaacatg aaagacatgc cagcactatc ttagaagaaa ctggtcacat
    24781 tgagatttta aatgaacttc aaatcgagga agcgatgagg gaagaagcag gcgctgatga
    24841 ccttgaaact gagcaagatc aaactgaaaa tcaagacttg aaagagatgg gcttgaaggt
    24901 cgagcaaagt tatgatattg cccaggtggc tacggatgtg actgcttatg ttcaaacgat
    24961 tattgatgac atggatgttg aggctacact ttcaaatgat tataaccgtc gtagcatcaa
    25021 tttgcaaatt gatactaacg aaccaggtcg tattatcggc taccatggta aagtcttgaa
    25081 ggccttgcaa ctgttggctc aaaattatct ttacaactgc tattcaagaa ccttctatat
    25141 cactattaat gtcaatgatt atgttgaaca ccgtgcagaa gtcttgcaga cctatgcgca
    25201 aaaattggcg attcgtgttt tagaagaagg acgtagtcat caaacagatc caatgtcgaa
    25261 tagtgaacgc aagattatcc accgtattat ttcacgtatg gatggcgtga ccagttactc
    25321 tgaaggtgat gagccaaatc gctatgtcgt tgtagataca gaataagtaa aatcagggtt
    25381 gacctgattt tttgctagct agaggaggtt aaactgatgt tgaataagat aagagactat
    25441 ctagactttt ctggtttgca gtaccgtagt cctgataaag cgggggcaga gcgagagaag
    25501 atgctggcgt tccgccacaa aggacaagag gcccgaaagg cttttacaga actggccaaa
    25561 gcctttcaag caagccatcc agaatggcaa ctccaacaga ctagtcagtg gatgaatcag
    25621 gcccagcgtt tgagaccaca tttttgggtt tatctacaga gagacggaca agtgacagaa
    25681 cctatgatgg ccttacgttt gtatgggaca tctactgact ttggaatttc tttggaagtc
    25741 agtttcatcg aacgtaagaa ggatgagcaa actttagaga aacaggccaa gattttagac
    25801 ataccaaccg ttaaaggaat ttattatcta gcctactctg atggccaaag tcaacggtgg
    25861 gaggcgaacg aagaaaagcg tcgtacttta cgcgagaagg tgagaagtca agaagttcga
    25921 aaagttttag tgaaggtaga tgttcctatg acagaaaatt cgtctgaaga agaaatcgta
    25981 gaaggcttat tgaagtctta ttctaaaatt cttccctatt atctagctac gagaaaataa
    26041 gataatttgt aaaacatcat aaatcataca gtccaagagt gaacagtccg ctgtgtaatt
    26101 cttggtcttt ttgtttgcgc tttcgcatta tataataaac ttacaaaaac aattcaaaag
    26161 gagaacaatt atggaagtcg tttcaagtgt tctaaattgg ttttctagca atattttgca
    26221 gaatcccgca tttttcgtag gtttattggt gttgatagga tatgcacttt tgaaaaaacc
    26281 tgcccatgac gttttttcag ggtttgttaa agcaacagta gggtatatgt tgcttaacgt
    26341 gggtgctggt ggtttggtta caacctttcg tccaatctta gcagctctta actacaaatt
    26401 ccaaattggt gcagcggtta tcgaccctta ctttggactt gctgcagcaa acaacaaaat
    26461 tgcagcagag tttccagatt ttgttggaac tgcaactaca gctctattga ttggttttgg
    26521 aataaatatc ttgctcgtag ctcttcgaaa gattacgaag gtaagaaccc tctttattac
    26581 tggtcacatc atggtacaac aagctgcaac agtatctctt atggttctat tcttagtacc
    26641 acaattgcgc aatgcttacg gtacagcagc gattggtatc atctgtggac tttactgggc
    26701 agttagttca aatatgactg ttgaggcaac tcaacgcttg actggtggtg gcggatttgc
    26761 gattggtcac caacagcaat ttgcaatctg gtttgtagat aaagtagcag gacgctttgg
    26821 taagaaagaa gaaagtttag acaatcttaa attacctaag ttcctctcaa tcttccacga
    26881 tacagttgtt gcatctgcta ccttgatgct cgtattcttc ggggccattc ttttaatctt
    26941 gggtccagac attatgtcta ataaagaagt catcacttca ggaactctat tcaatcctgc
    27001 taaacaagat ttctttatgt acattatcca aacagccttt accttctcag tttacttgtt
    27061 cgttttgatg caaggtgtcc gaatgttcgt atctgagtta acaaacgctt tccaaggtat
    27121 ttcaaacaaa ttgttgccag gttcattccc agcggttgac gttgcagctt cttatggatt
    27181 tggttctcca aatgctgtct tgtcaggatt tacctttggt ttgattggtc aattgattac
    27241 aattgtcttg ctcatcgtct ttaaaaatcc gattcttatt attacaggat ttgtaccagt
    27301 gttctttgac aatgcagcca ttgcggtcta cgctgataaa cgcggcggat ggaaagcggc
    27361 tgttatcctt tcctttatat caggtgtcct tcaagttgct ctaggagctc tttgtgtggc
    27421 ccttctcgat ttggcatctt atggtggcta ccatggaaat atcgactttg aattcccatg
    27481 gcttggattt ggatatatct tcaaatacct tggtattgtt ggttatgtac ttgtgtgtct
    27541 cttcttgctt gttattcctc aacttcaatt tgccaaagca aaagataaag agaaatatta
    27601 caacggtgaa gttcaagaag aagcttagta tctagaaaag gagaaataaa atggttaaag
    27661 tattagcagc gtgcggaaat ggaatgggtt catcaatggt tatcaagatg aaggttgaaa
    27721 atgctctccg taagcttaat caaacagatt ttacagtcaa ttcatgcagt gtcggtgaag
    27781 ctaaaggttt agcagtagga tatgacatcg taatcgcttc tcttcatttg attcaagaat
    27841 tggaagggcg aactaatggg aagttaattg ggcttgataa cttgatggat gataaagaaa
    27901 tcaccgaaaa actcagtcaa gcactacagt aaaaggttgg aggggctgga cagaaactga
    27961 gagttatcgt ttctgtcctt ctccctcttt aaataaagga ggcagatatg aatttaaaac
    28021 aagctttaat tgacaatgac tcgatccgac taggtttaga ggctaacaat tggaaagaag
    28081 cagtcaaggt agcagtagat cccttaattg aaagtggggc aattttgcca gagtattacg
    28141 atgctatcat tgaatcgact gaagagtatg ggccttacta tatcttgatg ccaggtatgg
    28201 ctatgcccca cgctagacct gaagctggtg tgcaaagtga tgccttttca ttgattacct
    28261 tacaaaatcc tgttgtattt tcagatggga aagaggtatc tgttttgttg gcactagcag
    28321 caacaagttc aaaaattcac acaagtgtag ccattccaca aattattgcc ctgtttgaat
    28381 tagaagattc tattgcacgt ttacaggctt gccagactaa agaagatgtc ttggctatga
    28441 ttgaagaatc taaggatagc ccttatctcg aaggattgga cttggaaagt tagaaagagg
    28501 aataaagaaa tgacaaaaag aatacctaat ttacaagttg cattagacca ttcagacttg
    28561 caaggagcga ttaaagcagc tgtttctgtt ggtcaggaag tagatattat cgaagctgga
    28621 actgtttgct tgcttcaagt tggaagtgaa ctggctgaag tcttgcgtag ccttttccca
    28681 gataagatta ttgtggcaga cacaaaatgt gctgatgctg gtggaacagt tgctaaaaat
    28741 aatgcggttc gtggagcaga ctggatgact tgtatctgtt gtgcaaccat ccctactatg
    28801 gaagcagctc taaaggctat caagactgaa cgaggagaac gaggcgaaat ccagatcgag
    28861 ctttatggcg attggacttt tgaacaagct cagctttggc tagatgcagg tatctcacaa
    28921 gctatttatc accaatctcg tgatgctctt cttgctggtg aaacttgggg tgaaaaagac
    28981 cttaataagg ttaaaaaact cattgacatg ggcttccgtg tatctgtaac aggtggtcta
    29041 gatgtagata ctctcaaact ctttgaaggt gttgatgtct ttacctttat cgcaggtcgt
    29101 ggaattacag aggctgcgga tccagcagga gcagcgcgtg ccttcaagaa tgaaatcaaa
    29161 cgaatttggg ggtaaatcat ggtacgtcca attggaattt atgaaaaggc aaccccaaca
    29221 cactttactt ggctagaacg tttaaatttt gccaaggagt taggctttga ttttgtcgag
    29281 atgtctattg acgaacgtga cgagcgttta gcaagacttg actggagtaa ggaagaacgc
    29341 ttggaagttg tcaaagcaat ctatggaact ggtgttcgta ttccttctat ctgtttttca
    29401 ggccatcgtc gctacccatt gggttcaaaa gatccagttc tagaggaaaa atctctagaa
    29461 ctcatgaaaa aatgtatcga attagctcaa gacttgggag ttcgtacgat tcaattagct
    29521 ggttacgatg tttactatga ggaaaagtca ccccagacac gccaacgttt tatcaaaaat
    29581 ttgagaaaag cctgtgactg ggctgaagaa gctcaggtgg tacttgctat tgaaattatg
    29641 gatgatcctt tcatcaatag catcgaaaaa tatttggcta tagaaaaaga gattgactct
    29701 cccttcctct ttgtatatcc agatattggt aatgtgtctg catggcataa tgatatctat
    29761 agtgagtttt atcttggtca tcatgccatc gcagctctcc atctcaagga tacttatgca
    29821 gtgacagaaa gttcaagggg ccagttccga gatgtacctt ttgggcaagg ttgtgtcaaa
    29881 tgggaagaag ctttcgatat tttaaaggaa accaattata atggaccttt cctaatcgaa
    29941 atgtggtctg aaaattgtga aacagtagaa gaaacacgcg cagccattca agaggcgcaa
    30001 gcttttctct atccactcat taagaaagca ggtttgatgt aagatgaatc aagtaatcaa
    30061 tgctatgcgt aaacgagtct gtgatgccaa tcaatcattg ccaaaacatg gacttgtcaa
    30121 atttacctgg gggaatgtat ctgaagtcaa tcgcgaactc ggtgtcattg ttatcaaacc
    30181 atcaggcgtg gattatgacg aattgacacc tgaaaacatg gtagtgactg atctagatgg
    30241 taagatccta gaaggggatt taagaccatc ttccgacctc ccaactcatg tgcaattata
    30301 taaggcttgg tcagaaattg gtagtgtggt tcacacccat tcgacagaag ctgttgcttg
    30361 ggctcaggca ggtcgtgata ttcctttcta cggaacaacc catgcagatt atttctacgg
    30421 ttcaatccct tgcgcccgta gtttgaccaa ggacgaagta gaagtggcct atgaaaaaga
    30481 tactggcctg gttatcgtag aagagtttga acatcgcgga cttaacccgg ttgaagtacc
    30541 aggaattgtt gtacgcaatc acggtccatt cacctggggc aaaaatccag agaatgctgt
    30601 ttatcactct gtcgtactag aggaagtatc aaagatgaat cgctttacag aacaaatcaa
    30661 tccaagagtt gaacctgctc cccagtacat actagaaaaa cactaccaac gtaaacatgg
    30721 accaaatgct tattatggtc aaaagtaaga acgatgaagg aggagaaaaa gataaattta
    30781 gctcctcttt ttacatttga tttttattga gagtaaagtt ggagttgaag taattttgaa
    30841 agatttttta gaaatagcgc ttgatatata tggtaaaata aaaagaattg ctgtgatatc
    30901 aatagatttg ggggattttt taatatggta ctggataagg caagttgtga tttgcttcaa
    30961 tatttgatgg atcaagaaac gtccaaaacg attatggcga tttcgaaaga tttgaaagag
    31021 tcaagaagga aaatttatta tcacattgac aaaatcaatg ctgctctggt tgacgaggcg
    31081 cttcacatca ttagtattcc acgaattggt attcacttaa cggaagagca gagagatgct
    31141 tgttgtaaac tattatcgga agtagattcg tacgattata tcatgagtgc gcatgaacgt
    31201 atgatgataa tgttactatg gataggtatt tctaaagaac gtattactat tgaaaaattg
    31261 atagagttaa cagaggtatc taggaatact gttctcaatg atttgaatag tattcgttat
    31321 caactaactt tggaacaata tcaggtgacc ttgcaagtga gcaagtcaca gggataccac
    31381 cttcatgccc accctcttaa taaaattcag tatcttcaat cgcttctata tcatattttt
    31441 atggaagaaa atgccacttt tgtatctatt ttagaagata agatgaaaga gaggttagat
    31501 gatgagtgtt tgctttctgt tgaaatgaac caatttttta aggaacaggt tcctttagtt
    31561 gaacaagatt tagggaagaa aataaaccat catgaaataa cttttatgtt gcaggttcta
    31621 ccttatttgc tgttaagctg tcataatgtt gaacagtatc aagaaagaca tcaggatata
    31681 gagaaagaat tttctttgat aagaaaaaga atagagtatc aggtgtctaa gaaattagga
    31741 gaacggttgt ttcaaaagtt tgaaatttct ttgtcaggac ttgaagtttc tcttgtagct
    31801 gttctcctcc tctcctatcg taaagatttg gatattcatg cagaaagtga tgattttcgg
    31861 caattaaaac ttgctttaga agaatttatc tggtattttg aatcacaaat ccgaatggag
    31921 attgagaaca aggatgattt gttacgaaat ttgatgatcc actgtaaagc cttgttattt
    31981 agaaagactt acggtatttt ttctaaaaat cctctaacaa aacaaattcg atccaagtat
    32041 ggagaattat ttttagtcac tagaaaatct gcggaaattt tagaaggagc atggtttatt
    32101 cggctaacag acgatgatat tgcctatttg acgattcata ttggaggatt tttaaagtat
    32161 acaccatcgt ctcaaaaaaa tatgaaaaaa gtttatctcg tttgtgatga aggtgttgcg
    32221 gtttcgagac ttttgctgaa acaatgcaaa ctttattttc caaatgagca aattgacact
    32281 gtatttacaa cagaacaatt taagagtgtg gaagatattg cacaagttga tgtagtgatt
    32341 actactaatg atgatttgga tagcagattt ccgattttaa gggttaatcc tatccttgaa
    32401 gcagaagata ttttgaaaat gctagactat cttaaacaca atatatttcg taataagagc
    32461 aaaagtttca gtgaaaatct ttctagtctt atttcgtctt atattgtaga cagcaagttg
    32521 gctagtaagt tccaagaaga ggttcaaaca cttataaata aagaaatagt agttcaagct
    32581 tttttggaag atatttgaag gacagtccaa tgatgaacac aaacctgtgt ttttcttggt
    32641 cttttttagt gttttgaagg gtggtatact aatctcaaag ataacaatta tatccaaagg
    32701 aggcaacata tgccaaacgt caaagaaatt acaagagagt catggatttt agccactttc
    32761 ccagagtggg gaacatggtt gaacgaagaa atcgaagaag aagtcgtacc tgaaggcaac
    32821 tttgccatgt ggtggctagg caactgtggt acttggatta agacaccagc tggtgctaac
    32881 gttgtcatgg acctttggtc aaaccgtgga aaatcaacca aaaaagtgaa agatatggtt
    32941 cgtgggcacc aaatggcaaa tatggcaggt gttcgtaagt tgcaaccaaa cttgcgtgtt
    33001 cagccaatgg ttatcgatcc atttgctatc aacgaactag actattactt agtttcacac
    33061 ttccacagtg atcatatcga cccatacaca gctgcagcaa ttctcaacaa tcctaagtta
    33121 gagcatgtta agtttatcgg tccttaccac tgtggacgaa tctgggaagg atggggtgtt
    33181 ccaaaagaac gtatcatcgt tgttaaacca ggtgacacta tcgaattaaa agatatgaag
    33241 attcatgcag tagaatcatt tgaccgtact tgcttagtaa ctctcccagt gaacggtgct
    33301 gatgagacag gcggtgaact tgctggcttg gctgttacag atgaagaaat ggctcaaaag
    33361 gctgttaact atatctttga aacaccaggt ggaaccatct atcatggtgc agattctcac
    33421 ttctcaaact attttgcaaa acatggtaaa gactttaaaa ttgatgttgc tttgaataac
    33481 tatggtgaaa atccggtagg tatccaagac aaaatgacat ctatcgacct tcttcgtatg
    33541 gcagaaaatc tgcgtaccaa agtcattatc ccagttcact atgatatctg gtctaacttc
    33601 atggcttcta ctaatgagat tctagaactt tggaaaatgc gaaaagatcg cttgcaatac
    33661 gatttccatc catttatctg ggaagttggc ggtaagtaca cttatcctca agatcaacac
    33721 ttagtagaat accatcatcc acgtggtttt gatgattgtt ttgaacaaga ctctaacatt
    33781 caatttaaag ctttgctata atataaaaat attctttgga ggttatccgt atgttgcatg
    33841 atacggataa ttttcatata atagtaaaat agaatgtgtg attcaataat cacctcaaat
    33901 agaaaggaaa ttctatgtca aatctatctg ttaatgcaat tcgttttcta ggtattgacg
    33961 ccattaataa agccaactca ggtcatccag gtgtggttat gggagcggct ccgatggctt
    34021 acagcctctt tacaaaacaa cttcatatca atccagctca accaaactgg attaaccgcg
    34081 accgctttat tctttcagca ggtcatggct caatgctcct ttatgctctt cttcaccttt
    34141 ctggttttga agatgtcagc atgaatgaga ttaagagctt ccgtcaatgg ggttcaaaaa
    34201 caccaggtca cccagaattt ggtcatacgg cagggattga tgctacgaca ggtcctctag
    34261 ggcaagggat ttcaactgct actggttttg cccaagcaga acgtttcttg gcagccaaat
    34321 ataaccgtga aggctacaat atctttgacc actatactta cgttatctgt ggagacggag
    34381 acttgatgga aggtgtctca agcgaggcag cttcatacgc aggtttgcaa aaacttgata
    34441 agttggttgt tctttatgat tcaaatgata tcaacttgga tggtgagaca aaggattcct
    34501 ttacagaaag tgttcgtgac cgttacaatg cctacggttg gcatactgcc ttggttgaaa
    34561 atggaacaga cttggaagcc atccatgctg ctatcgaaac agcaaaagct tcaggcaagc
    34621 catctttgat tgaagtgaag acggttattg gatacggttc tccaaacaaa caaggaacta
    34681 atgctgtaca cggcgcccct cttggagcag atgaaactgc atcaactcgc caagccctcg
    34741 gttgggacta cgaaccattt gaaattccag aacaagtata tgctgatttc aaagaacatg
    34801 ttgcagaccg tggcgcatca gcttatcaag cttggactaa attagttgca gattataaag
    34861 aagttcatcc agaactggct gcagaagtag aagccatcat cgacggacgt gatccagtcg
    34921 aagtgactcc agcagacttc ccagctttag aaaatggttt ttctcaagca actcgtaatt
    34981 caagtcaaga tgccttgaat gttgtggcag ctaaattacc aaccttccta ggtggatcag
    35041 ctgaccttgc tcactcaaac atgacttata tcaagacgga tggacttcaa gacgatgcca
    35101 atcgcttgaa tcgtaacatt cagtttggtg ttcgtgaatt tgcaatggga acaatcttga
    35161 acgggatggc ccttcatggt ggacttcgtg tatacggtgg aactttcttc gtcttctctg
    35221 actatgtgaa ggcagctgtc cgcttgtcag ccttacaagg acttcctgtg acttatgtct
    35281 ttacccatga ttcaatcgca gttggggaag atggtccgac tcacgaacca gttgagcatt
    35341 tagcaggtct tcgtgctatg ccaaatctaa atgttttccg tccagcagat gcgcgtgaaa
    35401 cgcaagcagc ttggtacctt gcagtgacaa gtgagaaaac accaactgcc cttgtcttga
    35461 cacgtcaaaa cttgactgtt gaagatggaa cagacttcga caaggttgct aaaggtgctt
    35521 atgttgtata tgaaaatgca gccgactttg ataccatctt gattgcgaca ggttcagagg
    35581 ttaatcttgc tgtctcagct gctaaagaat tggctagtca aggcgaaaaa atccgcgtag
    35641 tcagcatgcc atctacagat gtctttgata aacaagatgc agcttacaag gaagagattc
    35701 ttccaaatgc agtccgccgt cgtgttgcag tcgaaatggg tgcaagtcaa aactggtaca
    35761 aatatgttgg tctcgatggt gccgttctag gtattgatac cttcggagcc tctgccccag
    35821 caccaaaagt attggcagaa tatggcttta ctgtagaaaa tcttgtaaaa attgttcgaa
    35881 acttgaaata atcctaaaaa tcagggcgta agctctggtt tttcttacca gaaaagtaag
    35941 gtacaatctt gtaaaagtag ctgaaatttg atatagtagt cctatgtaaa agacaaagga
    36001 gaaaacaatg aatccaaata ttactttttt aatcatgctt gtaggtatga tggccttgat
    36061 gttctttatg caacgttctc aaaagaaaca agctcaaaag cgtatggaaa gcttaaataa
    36121 actacaaaaa ggctatgaag tgattacaat cggtggactt tatggaacag tcgatgaagt
    36181 agatacggag aagggaacaa tagttcttga cgtagatgga gtttacttga cttttgaact
    36241 agctgctatc aagacagtat taccgctgaa agaaacagct tcactagaag gcgcaattga
    36301 aaaataagac gggatcacga actcccgttt ttctataaaa gaaaggaaat gggatgaaaa
    36361 aattagtctt tgtctgtctg ggaaatattt gccgtagccc tatggccgag tttgttatga
    36421 aatcaatgac agataactac gaaatccaaa gtcgagcaac ttcctcttgg gaacatggca
    36481 atccgattca taaggggact cagggaattt ttcaagagta tgagattcct tatgacaaga
    36541 acaagacatc gcttcagatt agtaaggaag attttgaagc ctttgattat attatcggaa
    36601 tggacgcttc aaatatttct gacttatgtc agatgtgtcc agtagactgt caagataaga
    36661 tttactcatt ttcatctgaa agtgttccag acccttggta tacaggagat tttgaagaaa
    36721 cctatcgacg tgttcaagag ggctgtcaag cttggttaga acgtttagaa aaggagagtt
    36781 aaggtggaaa atcttacgaa tttttacgaa aagtatcgtg tctatctgac tcgtccacgt
    36841 ttagagcttt tggcagtagt taccattgtt ttttgtgctg tactcgtctt ttttctaaat
    36901 attccaggaa aaggtgtctt aaaactcgat aatggaacga ttgtttatga tggcagtctt
    36961 gtccgtggta aaatgaatgg ccaaggtacc attaccttcc aaaatggaga ccaatataca
    37021 ggtggcttca acaatggagc cttcaacgga aaaggtacct ttcaatctaa agaaggctgg
    37081 acctacgaag gtgattttgt aaatggtcag gctgaaggaa aagggaaact aacaacagaa
    37141 caagaagtcg tttatgaagg aacttttaaa caaggcgttt ttcaacaaaa ataaagcctc
    37201 cttatcaaag gaggtattat tagaatcaca aggtaagcgc ttacctgtaa atccctttct
    37261 ttccaaatcc ctcttccaag caagtttgtg aaataaaaaa tatttgaaat aaatttcaca
    37321 aacttcaaag ataaaacttg ataagaaaag aaaatgagaa aagtttcaca agagtttaaa
    37381 aattctttgt gaaatgttta tgaaactgtt tacaaagttg aaataatgcg ttataataaa
    37441 cttgtgaaaa aattaacaaa ggatatcgtt ccttgaaagc tatggaggaa aatatggctg
    37501 ataaaaaaac tgtgacacca gaggaaaaga aactcgttgc tgaaaaacac gtagatgagt
    37561 tggttcaaaa agctctagtt gcccttgaag aaatgcgtaa attggatcaa gaacaagttg
    37621 actacatcgt tgccaaagca tcagtagcag ctttggatgc ccacggagaa ttggctttac
    37681 atgcctttga agaaacagga cgtggtgtat ttgaagacaa agcaactaag aacttgtttg
    37741 cttgtgaaca cgtagtaaac aatatgcgcc acactaagac agttggcgtt atcgaagaag
    37801 acgatgtaac aggattgact cttattgctg aaccagttgg tgttgtttgt ggtattactc
    37861 caacaacaaa cccaacatca acagcaatct tcaaatcatt gatttcattg aagacacgta
    37921 acccaatcgt ctttgccttc catccatcag cacaagaatc atctgctcat gcagctcgta
    37981 tcgtccgcga tgcagctatc gcagctggtg ctcctgaaaa ctgtgtgcaa tggattactc
    38041 aaccatctat ggaagcaaca agtgccctta tgaaccacga aggtgttgcg acaatccttg
    38101 caacaggtgg taatgccatg gttaaggcgg cttattcatg tggtaaacca gctcttgggg
    38161 taggtgccgg aaacgttcca gcttatgttg aaaaatcagc aaacattcgt caagcagcac
    38221 acgatatcgt catgtctaaa tcatttgata acggtatggt ctgtgcatct gaacaagcag
    38281 ttatcattga taaagaaatt tacgatgaat ttgtagcaga gttcaaatct taccacactt
    38341 actttgtaaa caaaaaagaa aaagctcttc ttgaagagtt ctgcttcggc gtcaaagcaa
    38401 acagcaaaaa ctgtgctggt gcaaaattga acgctgacat cgttggtaaa ccagcaactt
    38461 ggattgcaga acaagcagga tttacagttc cagaaggaac aaacattctt gctgcagaat
    38521 gtaaagaagt tggcgaaaat gagccattga ctcgtgaaaa attgtcacca gttattgcag
    38581 ttttgaaatc tgaaagccgt gaagatggta ttactaaggc tcgtcaaatg gttgaattta
    38641 acggtcttgg acactcagca gctatccaca cagctgacga agaattgact aaagaatttg
    38701 gtaaagctgt taaagctatt cgtgttatct gtaactcacc ttctactttt ggtggtatcg
    38761 gggacgttta caatgccttc ttgccatcat tgacacttgg atgtggttct tacggacgca
    38821 actcagttgg ggataacgtt agtgccatta acctcttgaa tatcaaaaaa gtcggaagac
    38881 ggagaaataa catgcaatgg atgaaacttc cttcaaaaac atactttgaa cgtgattcaa
    38941 ttcaatacct tcaaaaatgt cgtgacgttg aacgtgtcat gatcgttact gaccatgcca
    39001 tggtagagct tggtttcctt gatcgtatca tcgaacaact ggaccttcgt cgcaataagg
    39061 ttgtttacca aatctttgcg gatgtagaac cggatccaga tatcacaact gtaaaccgtg
    39121 gtactgagat tatgcgtgcc ttcaaaccag ataccatcat cgcactcggt ggtgggtctc
    39181 caatggatgc tgccaaagta atgtggctct tctacgagca accagaagtg gacttccgtg
    39241 accttgtcca aaaattcatg gatatccgta aacgtgcctt caagttccca ttgcttggta
    39301 agaagactaa attcatcgcg attccaacta catctggtac aggatctgaa gtaacaccat
    39361 ttgccgttat ctctgataaa gcaaacaacc gtaaataccc aatcgctgac tactcattga
    39421 caccaactgt ggcaatcgta gatcctgctt tggtattgac agttccagga tttgttgctg
    39481 ctgatactgg tatggacgta ttgactcacg cgacagaagc atacgtatca caaatggcta
    39541 gtgactacac tgatggttta gcacttcaag ccattaaatt ggtctttgaa aatctcgaaa
    39601 gctcagttaa gaatgcagac ttccactcac gtgagaaaat gcataacgct tcaacaatcg
    39661 ctggtatggc ctttgccaat gccttcctag gtatttctca ctcaatggcc cataagattg
    39721 gtgcgcaatt ccacacaatc cacggtcgta caaatgctat cttgcttcca tacgttatcc
    39781 gttacaacgg tacacgtcca gctaagacag caacatggcc taagtacaac tactaccgtg
    39841 cagatgaaaa ataccaagat atcgcacgca tgcttggact tccagcttct actccagaag
    39901 aaggggttga atcttacgca aaagctgtct acgaactcgg tgaacgtatt gggatccaaa
    39961 tgaattttag agaccaagga attgacgaaa aagaatggaa agaacattct cgtgaattag
    40021 ccttcctggc ttatgaagac caatgttcac cagctaaccc acgtcttcca atggtagacc
    40081 atatgcaaga aatcatcgaa gatgcatact atggctacaa agaaagacca ggacgccgta
    40141 aataattgtt tatcagtcta gaagcaagac aaaaactcaa tttgagggaa agatccagta
    40201 atttttctat gataaaaggc atcctatcaa ggtttttgaa cacctgatag gatgcctttt
    40261 tatgatattg aggccttttt gccctttttg aaaaactaga atagaaacaa aatatataat
    40321 agattgaaac tggaatagta cacttctgct tctaaaacat tgttagaatt cgatttgact
    40381 gtcctgatcg atttgtccta tt
//
LOCUS       DAVMAH010000013        40316 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVMAH010000013 DAVMAH010000000
VERSION     DAVMAH010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40316
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.013"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            200..880
                     /locus_tag="VYO94_000632"
     CDS             200..880
                     /locus_tag="VYO94_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1759302.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLRLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
     gene            840..1220
                     /locus_tag="VYO94_000633"
     CDS             840..1220
                     /locus_tag="VYO94_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV1759303.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            1230..1517
                     /locus_tag="VYO94_000634"
     CDS             1230..1517
                     /locus_tag="VYO94_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1759304.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            1518..2276
                     /locus_tag="VYO94_000635"
     CDS             1518..2276
                     /locus_tag="VYO94_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1759305.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDILLDGQSIVENKKDFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKAQGRDKKEVTEEALQLLERVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAITDRIIFLDQGKI
                     AEEGTAQAFFTNLQTKRAQEFLNVFDFSQFGSYL"
     gene            2288..3159
                     /locus_tag="VYO94_000636"
                     /pseudo
     CDS             2288..3159
                     /locus_tag="VYO94_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(3246..3893)
                     /locus_tag="VYO94_000637"
     CDS             complement(3246..3893)
                     /locus_tag="VYO94_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759306.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(3890..4588)
                     /locus_tag="VYO94_000638"
     CDS             complement(3890..4588)
                     /locus_tag="VYO94_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759307.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYVLG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(4598..5350)
                     /locus_tag="VYO94_000639"
     CDS             complement(4598..5350)
                     /locus_tag="VYO94_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759308.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(5350..6114)
                     /locus_tag="VYO94_000640"
     CDS             complement(5350..6114)
                     /locus_tag="VYO94_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759309.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(6210..6613)
                     /locus_tag="VYO94_000641"
                     /pseudo
     CDS             complement(6210..6613)
                     /locus_tag="VYO94_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6793..7425)
                     /locus_tag="VYO94_000642"
     CDS             complement(6793..7425)
                     /locus_tag="VYO94_000642"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV1759310.1"
                     /translation="MILAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVDAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(7459..8160)
                     /gene="pyrF"
                     /locus_tag="VYO94_000643"
     CDS             complement(7459..8160)
                     /gene="pyrF"
                     /locus_tag="VYO94_000643"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV1759311.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(8426..9592)
                     /gene="divIB"
                     /locus_tag="VYO94_000644"
     CDS             complement(8426..9592)
                     /gene="divIB"
                     /locus_tag="VYO94_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV1759312.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQKDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESN"
     gene            complement(9602..10660)
                     /locus_tag="VYO94_000645"
     CDS             complement(9602..10660)
                     /locus_tag="VYO94_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV1759313.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(10662..12014)
                     /locus_tag="VYO94_000646"
     CDS             complement(10662..12014)
                     /locus_tag="VYO94_000646"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV1759314.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVIPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(12118..12759)
                     /locus_tag="VYO94_000647"
     CDS             complement(12118..12759)
                     /locus_tag="VYO94_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759315.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTIL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(12761..14782)
                     /locus_tag="VYO94_000648"
     CDS             complement(12761..14782)
                     /locus_tag="VYO94_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1759316.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(14853..15148)
                     /locus_tag="VYO94_000649"
                     /pseudo
     CDS             complement(14853..15148)
                     /locus_tag="VYO94_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            complement(15513..15767)
                     /locus_tag="VYO94_000650"
     CDS             complement(15513..15767)
                     /locus_tag="VYO94_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV1759317.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(15787..17628)
                     /gene="typA"
                     /locus_tag="VYO94_000651"
     CDS             complement(15787..17628)
                     /gene="typA"
                     /locus_tag="VYO94_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV1759318.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPIDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            17790..18515
                     /locus_tag="VYO94_000652"
     CDS             17790..18515
                     /locus_tag="VYO94_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1759319.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDATGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(18555..18782)
                     /locus_tag="VYO94_000653"
     CDS             complement(18555..18782)
                     /locus_tag="VYO94_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759320.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(18871..19251)
                     /locus_tag="VYO94_000654"
     CDS             complement(18871..19251)
                     /locus_tag="VYO94_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1759321.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(19251..19520)
                     /locus_tag="VYO94_000655"
     CDS             complement(19251..19520)
                     /locus_tag="VYO94_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV1759322.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            19584..20492
                     /locus_tag="VYO94_000656"
     CDS             19584..20492
                     /locus_tag="VYO94_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1759323.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(20546..21301)
                     /locus_tag="VYO94_000657"
     CDS             complement(20546..21301)
                     /locus_tag="VYO94_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV1759324.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(21322..22251)
                     /locus_tag="VYO94_000658"
     CDS             complement(21322..22251)
                     /locus_tag="VYO94_000658"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV1759325.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(22266..22889)
                     /locus_tag="VYO94_000659"
     CDS             complement(22266..22889)
                     /locus_tag="VYO94_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV1759326.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(22882..24120)
                     /gene="hflX"
                     /locus_tag="VYO94_000660"
     CDS             complement(22882..24120)
                     /gene="hflX"
                     /locus_tag="VYO94_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV1759327.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(24113..24997)
                     /gene="miaA"
                     /locus_tag="VYO94_000661"
     CDS             complement(24113..24997)
                     /gene="miaA"
                     /locus_tag="VYO94_000661"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV1759328.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            25118..25288
                     /locus_tag="VYO94_000662"
     CDS             25118..25288
                     /locus_tag="VYO94_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV1759329.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(25336..26175)
                     /locus_tag="VYO94_000663"
     CDS             complement(25336..26175)
                     /locus_tag="VYO94_000663"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV1759330.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(26272..27231)
                     /locus_tag="VYO94_000664"
     CDS             complement(26272..27231)
                     /locus_tag="VYO94_000664"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV1759331.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(27358..28356)
                     /locus_tag="VYO94_000665"
     CDS             complement(27358..28356)
                     /locus_tag="VYO94_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1759332.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            complement(28406..29023)
                     /locus_tag="VYO94_000666"
     CDS             complement(28406..29023)
                     /locus_tag="VYO94_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1759333.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(29024..30745)
                     /gene="pabB"
                     /locus_tag="VYO94_000667"
     CDS             complement(29024..30745)
                     /gene="pabB"
                     /locus_tag="VYO94_000667"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV1759334.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLTVHKVPLLGEYLLYFTVHDRVETSPVPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(30814..37041)
                     /locus_tag="VYO94_000668"
     CDS             complement(30814..37041)
                     /locus_tag="VYO94_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEV1759335.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSITNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQLSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNSKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETVNQPVEQPKVETPAVEKQTEPTEEPKVEQAGEPVAPREDEQAPTA
                     PVEPEKQPEVPEEEKAVEETPKPEDKIKGIGTKEPVDKSELNNQIDKASSVSPIDYST
                     ASYNALGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDALNVDKTELNNTIADAKTK
                     VKEHYSDRSWQNLQTRVTEAEKVAANTDAKQSEVNSETASLKTAISGLNTDKVELENQ
                     LKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQEQINEAEKSLKTALADLSVD
                     KTALGSAIDTATKKNKENYTNQTWAELETVLTAAKSVNTNESKQSEVNEAVEKLTATI
                     EKLVELSEKPRLTLSIEKRDIDRKVTVTYTLENPANTQIKSITATLKKGEEVVNTVVL
                     TGDDVNNEAISAAFENLEYFKEYTLSTTMVYDRGNGQEETETLAAQPIQLDIKKVEIK
                     NIKETSLISVDPDGNETDKSLLSEKPTDITSYYLKISTHDNKVTRLAVDKIEEVEEGG
                     KTLFKVTAIAPDLIQRDSANKLGKTYTHYIAKKKVHKDNVYYDFNELVNAMNDNPNGT
                     FKLGSDLNAANVPTPYKEYVPKVFRGHLSSVEGEQYSIHNMARQLFSSIEGGSVKNIN
                     LANVDINMPWINDISPLARVVKNATVEKIKVTGNILGKDGVAGIVNKVDTGGLLQDVA
                     YIGKITGVGNKGSDIGGIAGEVWRGNIKKAYVEADIVGNKARVGGLVAKSDNGYDPNG
                     VNTYAFTSEAVVKGTIKVTTPVEVGGFISKSWIWGRILNTVTMMKVENGEEFYGSRDL
                     EVENGEYTHNWIDRNYVVKGVSEGAHSFKYSRSNRIQEISLEEANKKIESFGITADKF
                     EIKPLIEEKLNNIKLKADTYKDTQDYKADRELAYRNIEKLQPFYNKEWIVDQGNKIPA
                     GSNLLTKEVLSVTGMKGNNFVTDLSDADHIMIHYADKTNEIKAIAQKESQVQQVREYS
                     IEGLDDIVYTPNIVEKNRDNLAASITEKLSSFELQSPEVRQILDKRDASKDKNANSEA
                     RQNNYIRDLYLEESVTEVKNNISAIVKQLIENEDHQLNTDEDTERALIKKIEGNKAKL
                     MLGLAFLNRYYGVKFGDFNIKQLMMFKPDFYGNNVSLIDRLIEIGSKENNLRGHRTQD
                     SFREVLAKNTRSGNLIDFLKYNMELLTPDRDINDWFIHSTNGKVYVVEKQSREEGLKN
                     AKYRAFDNLSKGYHQKMILPLLNLTNTEAFLISTYNTISFGTANKYGKSMADVKNDID
                     LAASRHINYLDFWYRLATDEVKGKLAKDIVTPVWEGYKVWGHKWPSWMDRYGNFDDGK
                     GIYAPVRELYGPVGEYYGHNGAVAGAYATYYDNKNDNRHKVVFVMSDMLTEYGASAFT
                     HETTHVNDRVAYYGGHGHREGTFVEAFAQGMLQSPATEGHQGEYGALGLNMAFEREND
                     GNQWYNYNPNKLKSRDEINHYMKNYNEALMMLDHLEADAVLSQNIKDNSVWFKKVDKQ
                     YRTKDEYNKNLVQPNQWDLVRDLNDEEKTKTLTTINDLIENNFATKHGVGNGRYRPED
                     FVPNSAYVNVNMMSGIYGGNTSDGAPGALSFKHNAFRMWGYFGYENGFIGYVSNKYKD
                     ESKKAGENNLSDKYIIKKVSGDKFTTLEEWKIEWFKQVKEKAQKGFTAIEIDGNTINS
                     YARLKELFNEAVQKDLNELSNQTIKNKYRHTVALKEKVFKQLLKESDGFSGDLFTAPQ
                     A"
     gene            complement(37063..37626)
                     /locus_tag="VYO94_000669"
     CDS             complement(37063..37626)
                     /locus_tag="VYO94_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV1759336.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(37742..39433)
                     /locus_tag="VYO94_000670"
     CDS             complement(37742..39433)
                     /locus_tag="VYO94_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1759337.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VTFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(39430..40167)
                     /locus_tag="VYO94_000671"
     CDS             complement(39430..40167)
                     /locus_tag="VYO94_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1759338.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        11776 a         8875 c         7217 g        12448 t
ORIGIN      
        1 ataagtaagc gttcactttg tatattacaa aaatatctta actctttttc aaaacttttc
       61 aaatattttg tttggaaatt tcagaaattt tatgtctatg gtaaaaaatc cttataacgg
      121 caaaaaaaaa tagatattat ccaaagaaga ttttaagtgc tacaataact gtattatttc
      181 tagatgggag gttctatttt tggattggtc cattgttgaa caatatctac cactatatca
      241 aaaggcattc tttctgacct tgcatattgc agtttgggga attttgggat cctttctgct
      301 cggtttaatc gttagtatca tccgacatta tcgaatccct gttttggcgc aagtagcgac
      361 agcctacatt gaattgtcac gtaatacgcc ccttttgatt caactcttct ttctctactt
      421 cggtcttccc cgaatcggga ttgtcctatc ttcagaagtc tgtgcaacgc ttaggcttgt
      481 ctttttagga ggctcctata tggcagaatc tttccgaagt gggctggaag ccatcagtca
      541 aacccagcag gagattggcc tcgctattgg tctgacacct ctacaggtct ttcgctatgt
      601 ggttcttccg caagcaacag cggtggcact cccctccttt agtgccaatg tcattttcct
      661 tatcaaggaa acctctgttt tctcagcagt ggctttggcc gacctcatgt acgtcgccaa
      721 ggatttgatt ggtctctact atgagacaga cattgcgcta gctatgttgg tagttgctta
      781 tctgatcatg ctgctaccca tctcactggt ctttagctgg atagaaagga ggacccgcca
      841 tgcaggattc gggaatccaa gtactctttc aaggaaataa tctcctgaga atcttacagg
      901 ggttgggcgt tacgattggg atatccatcc tgtctgtcct cttatccatg atgttcggaa
      961 cagtcatggg aatcatcatg acctcccatt ctagaatcat acgattttta acacgattgt
     1021 atctggaatt tatccgtatc atgccccagc tggtgctact cttcatcgtt tactttggct
     1081 tggctcgaaa ctttaatatc aatatctcag gtgagacttc agctattatc atttttaccc
     1141 tctggggaac agctgaaatg ggagacttgg tacgtggagc tatcacttct ctccctaaac
     1201 atcagtttga aagtggatag gcactcggct tgactaatgt tcaactttac taccacatca
     1261 tcatcccaca agtcttaaga agactgctac cgcaggctat caatcttgtc actcggatga
     1321 ttaaaaccac ttcattagtt gttttgattg gggttgtgga agtgaccaaa gttggacaac
     1381 aaatcatcga tagcaatcgc ctgaccatcc caactgcttc attttggatt tatggaacca
     1441 ttctagtctt atatttcgca gtttgctacc ctatttccaa actatccact cacttagaaa
     1501 aacattggag aaactaaatg tctgaaacta tcttagaaat caaggaacta aaaaaatcct
     1561 tcggagacaa tcccatcctc caaggacttt ctctagaaat caaaaaaggg gaagttgttg
     1621 tcatcctggg gccatctggt tgtgggaaaa gtaccctcct tcgttgcctc aacggcttag
     1681 aaagtattca aggtggagat attcttctgg atggtcagtc tatcgttgaa aataaaaaag
     1741 attttcacct agttcgccaa aagattggca tggtctttca aagttatgaa ctctttcccc
     1801 atctggatgt cttacaaaac ctcatcctag gccctatcaa agctcaagga agggacaaga
     1861 aagaagtaac ggaagaagct ttgcaattac tagagcgtgt cggtttgctg gataaacaac
     1921 atagctttgc ccgtcaatta tctggtggac agaagcaacg tgttgcaatt gtccgtgccc
     1981 tcctaatgca tccagaaatc atcctttttg acgaggtgac tgcttcgctg gatccagaaa
     2041 tggtgcgtga ggtgctggaa cttatcaatg atttggccca agaaggccgt accatgattt
     2101 tagtaaccca cgaaatgcag tttgcccaag ccattactga ccggattatc ttcctcgacc
     2161 aagggaaaat cgctgaagaa ggaacagctc aagccttctt taccaatctg caaaccaaac
     2221 gagcccagga atttttaaac gtctttgact ttagccaatt cggctcatat ctatagagga
     2281 gattcttatg aaactattca aaccactctt aactgtttta gcacttgcct ttgcccttat
     2341 ctttatcact gcttgtagct caggtggaaa cgctggttca tcctctggaa aaacaactgc
     2401 caaagctcgc actatcgatg aaatcaaaaa aagcggtgaa ctgcgaatcg ccgtgtttgg
     2461 agataaaaaa ccgtttggct acgttgacaa tgatggttct taccaaggct acgctacgat
     2521 attgaactag ggaaccaact agctcaagac cttggtgtca aggttaaata catttcagtc
     2581 gatgccgcca accgtgcgga atacttgatt tcaaacaagg tagatattac tcttgctaac
     2641 tttacagtaa ctgacgaacg taagaaacaa gttgattttg cccttccata tatgaaagtt
     2701 tctctgggtg tcgtatcacc taagactggt ctcattacag acgtcaaaca acttgaaggt
     2761 aaaaccttaa ttgtcacaaa aggaacgact gctgagactt attttgaaaa gaatcatcca
     2821 gaaatcaaac tccaaaaata cgaccaatac agtgactctt accaagctct tcttgacgga
     2881 cgtggagatg ccttttcaac tgacaatacg gaagttctag cttgggcgct tgaaaataaa
     2941 ggatttgaag taggaattac ttccctcggt gatcccgata ccattgcggc agcagttcaa
     3001 aaagacaacc aagaattgct agacttcatc aataaagata ttgaaaaatt aggcaaggaa
     3061 aacttcttcc acaaggccta tgaaaaaaca cttcacccaa cctacggtga cgctgctaaa
     3121 gcagatgacc tggttgttga aggtggaaaa gttgattagt cattaactct taaaaggaac
     3181 tggattttaa gctccaatcc ctttttaaga ttttacctat aacatcctga gtctatctaa
     3241 gatgttcaat ctgaacacag tgtacatact ttatcttcta ttgcatatac tttatcacat
     3301 aagatacgaa tatcctcttc actatgacta gcaatcaaaa ttgttgtccc tttttcacta
     3361 gagagctttc taaacaatgt tctcatattt tctacacttg atttatccaa ggcattcata
     3421 ggttcatcta gtaaaagaat agagggattc tccataattg cttgagcaat ccctagcttt
     3481 ttcctcatac ctagcgaata agttttaact ttctggtctt tttgctcata tagaccaact
     3541 attttcagtg tatcattgat ttcctgatta ccaactactc ctcgtatgct tgccaaatat
     3601 tgtaaattct taaagccact ataataattt ataaaaccag gttcttcaat caaagctccc
     3661 aaattagctg gaatttttct ctcaggaaca atattttccc cattgattaa cacttctcca
     3721 taagacggac tatataaacc agctattaat ttaaacaata cacttttccc tgagccattc
     3781 gcaccagtaa ttcctataat ttccccctgt ttacaactaa aattaaggtt ttgaaaaaca
     3841 catgtttttt ttaatttcaa ctcaatattt tttaatatga ttatttcatt cattctataa
     3901 acctcctctt ttgacgagtg aaatagaaaa tacttttaaa aagaaagact aaaaatagca
     3961 actgaagaaa taaatctcgt cctatatctc cattccctcg attcaaaata taaaatagat
     4021 aattagttcg atttcctaca aatagaccac caaacacaat catgagtaaa aagaaactaa
     4081 cgcaagcaaa gttcatttgt acattcgctc ctagtacgta taacataaag caaaacaaga
     4141 ctaacacaca agcattcaaa gaatcaacta taaacaaaac tcctatatcc cagtttggta
     4201 actgtaacat aaattgaatc actagaactt ttaccatgat taaaatgagt ccataaagaa
     4261 aacaggtcca aatctgatac ctaatccaga gcttaataga agaaaatcga atcacttcca
     4321 taaagaaatc ggatgctctt ctacgatata caactgctag aaaaaatgta tgaataataa
     4381 accaatgaag caaccatata gataagacta aaaaagagtt ttgactcaga ttaggccctt
     4441 ttaaaatttc tataacaagt ctatcatttc cttctaacca ataccataat cctaaacaaa
     4501 tcaatatcca aaaaagaaca taaccccaaa agtacttggt atagattatc tgattcaacc
     4561 tccacatgtg actacttaac tttcccattt ccaactttta cactctcctc cagtttctat
     4621 gaacagaaaa tacagtcaat ggaattatga tagatagtaa tgtaagccaa taaatcaatg
     4681 catacggatt ggaatttacc atatactgaa aaattggcaa taatccaatt atcccattgt
     4741 ccaactgata aatccagaat aaggattcta caaataaaaa agtaaacaga aatactaagc
     4801 tcatgtttga ttttttaaac caagaaaaac tgctaatagt aagtaaggat aaaaagaaat
     4861 agtatgctat ataagagaaa aaaaatccta taaagaaact agcattgttt gcaatactta
     4921 taccataaaa ttctcttaaa aaatcaacct cctttatctc caaagagaag ctaaaaccat
     4981 tactaaatgc aattagaaaa atcaataaaa ataaagtcgc cgtccaaatc cccgtactaa
     5041 gagctgctaa tttgaaacta aaactggtaa agtgcttaat tgatttcaga cgaatgcgac
     5101 actccaacct attaaaatag ttattcatca aataaaaaaa gaacaatata tatgtgaacg
     5161 gaaagcaata tactccagtc gtcatatctt gaagtaaaac taagatccat tctaatacat
     5221 ttggatggat tgaatattgg cgacagcgca ataaatatac tgtactagat aaaacacagg
     5281 atagcagtaa tataaaataa accaatactg ctaagaaatc ttttttataa aattgaacaa
     5341 attgtttcat tatacatagt cctctgaatg tagaaaaaat gtaccataaa caaccaaaca
     5401 actaacaaat aaaataaaag caagatgccc actaactaag gaaagactga tatctttctg
     5461 atatcccaaa gctaatgttg tcacaggttc taagtaagat agccctaaaa tagcccaaaa
     5521 aataccacca accatcatat aggcaactgg gatgaaaata gctcctattt ttttcttcac
     5581 tagcaaagca ctagctagtc caaaaataga gaacacagcg ccccaaactc cataccagag
     5641 agtcgtcaca agactataga gcaactgatt ggaatcaaat aattctttta aggcaccact
     5701 ataatctcca atataaattt cctgataagg agtcactaaa agattaattc ctaataataa
     5761 taaatagggg agaaaaaaga ctagaaaaga agaaataatt gcagtactac ccacaatagc
     5821 cagatacttc tttttagaaa ttcgacacaa ttgtgctgtt agaaaatgac tctcagcatc
     5881 ctctattatc tgactagaat agggcagtgt acagataagt gcagctacta ggctaatcgg
     5941 tgaaaatcct cgaatagaag aagcggcaaa aaaaatggat aaaccttcaa ttttataaat
     6001 accattgaaa gcaaggaaat ttcctaaact catgcaaaga agggtcaaaa ataaagacat
     6061 ataaaatcga ggtgattgaa cgactcgtac aagattacaa atgaaaaatt ccatccttac
     6121 tcctccttat aataaaaata gggtgtagca ttcttttttc atgctacacc cacaatcaac
     6181 catctttaag gcttactctg acaagtaagt taataagaat ctggactcca agaacctgaa
     6241 gtatgaattc ttacatgatt tccaaattgt ggcgccatag ctaatctagt accagaacca
     6301 atataattgt caccacctcc attatagtac atgacaatcc tagagccaga ccccaatgaa
     6361 tataccgggg taatatctga cccactatag gcgctacgaa tagaggtatt taacctttta
     6421 ccgccaccag tgctgtcact attattaatt ccagcagagg cgttttcttt ctcaagctca
     6481 ctagttgtat ccgaacccca acgcggcaac gttaaatcat aatttccaat ctgtctagct
     6541 aaaactgtag ggagaaacaa actagatgca attgtaacta cgcaaaaaag gaatatattt
     6601 ttcttctttt catgacatcg tcctcctaag aagtgataaa caagatagtt gattgatcaa
     6661 tttgatacat attacatttt cattatatca ataaaagaaa gcgttgtcaa ttattttgtt
     6721 taaaatattg tcatatttta aacaaaatgg taaaagaggc tcggtagcct cgtctctctt
     6781 tatcttactg acctaacctt cttgccaatt ttcttggtct tctttaaagc gttttagaag
     6841 atcaaggccc tctggcgtga tgtaaccttc ttcttgggct agatggataa gctcgctata
     6901 gtttgaaagc gtcacaagtt taacaccagc atctgcaaag ttcttatctg cttttggcaa
     6961 ttggtagctg aaaatcgcta caactccaag cacatctgct ccttctcgct tggctgctgc
     7021 tacagcttca agaactgaac cacccgttga aataaggtct tcaaccacta ccattttttg
     7081 accttgagct acgcgacctt cgatttgatt accagctcca tggtcttttg gtttgctacg
     7141 gatgtaggca aaaggcaagt ccatcttatc agcaataatg gctccgtgtg gaatccctgc
     7201 tgttgcagtt cctgcaatca cttctacttc aggaaaggct tctttgatag catccacaaa
     7261 accattttca attagggtac gagtttctgg ataggctagt gtcacacgat tatcagtgta
     7321 aatcggtgac ttgataccag atgcccaagt gaagggttcc tctggtttga ggtaaacggc
     7381 ttggattttc aagaggtggc tagcgatatc tttagcaagt atcatggtat tctcctttta
     7441 tttttctaat ctagttcttt aattccagtc ctgtgtccat tcatccttga tggcatgata
     7501 agctgcaaca ggatcctcag cttgggtaat gggacgtccc actacgatat agtcactgcc
     7561 gatttgatag gcatcagcag gtgtcatgac tcgtttttga tctccaactg cagcaccagc
     7621 tggacgaatc cctggtgtca gacagataaa atctggattg gtagcctgct tgatgacttg
     7681 tacttcctga gccgagcaaa caacaccatc caagccagct tcagctgtct tcttggcata
     7741 gtgaatcaca gactcttgca gactggtttg gatattttga aactcctgca tctgggcttc
     7801 tgacgttgat gtgagctgcg ttacagcgat caatttggct tgacttccaa gaccttcacg
     7861 cgcagccttc atcatctcta caccaccagc cgcatgaaca ttggtcatat ccacaccaag
     7921 ctgagacaag accttcatgg ctgacttgac tgtattagga atgtcatgaa gtttgagatc
     7981 caaaaagaca ctatgaccca aaccttttaa gtaggacaca atctcaggcc ccgctgcgta
     8041 ataaagctcc atccctacct tgagataaag gctttcttct gctgggaaaa gagctaaaaa
     8101 ttccttgacc gcctcaaaac taggaaaatc aagagcaatg actggacgat gttctcgcat
     8161 aggtttctcc ttttaccttt actagtgaga gagtctggcc aacagaagcc acgaaaaaag
     8221 gaacctgcca acagcaaggt tccacgaaaa atgggtagtc tccacccttt caccgtctaa
     8281 ccttagctgc ctctctggac tgctttaaag gttttttact attctattat ttctactagc
     8341 acttgtcaag taaaaacatg gtcactaaag aactataaga gaaaaggtaa acctagcgac
     8401 gcgatgagcg ctgggtcgtt tgatttcaat tgctctcttc ctcttgtttt ttctgttctt
     8461 cttcctgttt tttctcagct tccttggcct cttgtttggc tttttcctca gcctccataa
     8521 ttaatttatc cgccacagtg taactgtaaa ttccagcttc catatcaatc acactcggtt
     8581 ctgacaattg tggcttaatc ttactgtaat atggcagttt cttactcatt tcagatagag
     8641 gaaccaagac ttcgtccgaa tcattcatgg tcaatcgaat taaatcggat gtcaccttgc
     8701 ttggggctaa ttccaccttt tggatagccg ccttgagttc tgggctaatt tgagcaagtt
     8761 ctgagacaaa aaccttgatt tgttcactat cattaaagag aactgataaa taagtttctg
     8821 gtaaactgtt cagactcaca gaactagtct caagctgacc actggaaaga ataggataat
     8881 gattttcacc agaaatatag taggccacaa tatcatattc cttgacctta atagtgaact
     8941 tagttggaaa ttgatagaca agttgagctg attcaaccca atagttagac ttaatctgct
     9001 tttcatattt tgccttgtct agcagaaggt taatcgtata atccgaatcc tgaatgcctg
     9061 aagcctgtcg aatatcatca gctgtagttt gcaccgttcc ctcaacacga atatctttca
     9121 tggtcgcata aggactgagc aagtaggcag agacaatcaa taaaagcaga cttggaaata
     9181 aaatcgtgaa ggctcgcaag atatggatac caggaatctt tgctttggct ggtttttcct
     9241 ttgtagcctt tttagaaagc tttttatcct gttcctcctt ctctttagac tctggttctt
     9301 ctttctcttc tttctctttg tcagcctctg aggatgctac tttttcttca gactcttcct
     9361 tagctgattc tgaatctttc tggtctgttt cactctcctg gtcctgttta tcctctgact
     9421 tctcagattc ttctcccatt cgagcttgtc tttccttttc cttctcctca gctagagccg
     9481 cctcttcttc agccttcttt tttagatatt cttggtttcg tttctgccat tctgataact
     9541 ctttcaattc ttcgagggtt tctttgtcct catttttctt atcttttgac atttactttc
     9601 cttatgataa atcttttttc aacaattgat aaaaatctgc tagagatttc aattccttag
     9661 aagctttcat cttagcttgg taatcttcct tgtgacttag taagtgagaa agcttctctt
     9721 ccaaactatc caaggtcaaa tcgctttctt gaaggtcttc tgcatagcct ttcttaacaa
     9781 agtaagctgc attttcaatc tggtcaccac gactagcttc acgaccaagc ggcacaatga
     9841 catgcaattt tgctatcgcc aagagctcaa aaatcgtatt ggcaccacct cgtgtcacaa
     9901 caatatcagc caattccatc aagggttgat agagatcggt cacatagtca acacgaaaaa
     9961 gattttgcct caactcattc agactagaat ctccagttag attgataata ttgtagcgct
    10021 ctgttagttc tttcttatgg tctgtcacca attggttaaa gacacgagcg cctgcagaac
    10081 cgccaacaaa caatacagtt ggcaatttgg gattaaagtg ggtttgaata tccaccaatt
    10141 catctggttc tggagtgttt ttgtccgaaa ccttggtcac cgctcccaca tgctcaacct
    10201 tagccaaact cgaagcttgt tcaaaggttg aatacatctt agtcgcaaat ttataggcga
    10261 ttttattggc caagcccata gacaggtcag attcgtgaat aaagacaggc actcctgaca
    10321 cacgcgcagc gataacaggc ggtactgaga caaagccccc ctttgaaaaa agggtctgtg
    10381 gacgcagtcg caacatgata aagagcgatt ggacaatccc ccaaccaact ttgaagacgt
    10441 ccagcatatt ttgccaagag aaatagcgac gcaattttcc agtcgcaata gaatggaagg
    10501 tgacatccaa acctgactta aggatttctt ggtgttcgat accacgcttg tccccgatat
    10561 agtggacttc ccaaccatct tcgatgaact tgggcattaa caaaagattg agggtaacgt
    10621 gtccaaccgt ccccccacct gtaaagacaa tttttttcat attattcttt taactccgct
    10681 actgtgtcga taaagaggtc gccacgtact tcaaagttag catacatatc ccagctagca
    10741 ttggcaggac taagaagaac cacatctcct tgagtcgcaa gctcataggc cttgcgggtc
    10801 gcatctgcaa tatctgtcgc ctccacataa gcgacaccag ccttgtctgc tgcccgtttg
    10861 acacgttctg cagattgacc caggatgacc atcttcttga gtccagtaat gtctggcacc
    10921 aattcgtcaa actcattgcc acggtccaaa ccacctgcaa tcaagacgac cttgctgttg
    10981 tcaaatcctg acaaggcttt ttgagtagcc aagatattag ttgatttact gtcgttatag
    11041 aatttaacac ccttgatgtc atccacaaac tggagacggt gtttgacacc accgaaggct
    11101 gaaagagttt ccttgatggt ttgattgtcc acatcacgaa gcttggctac agcaatagtc
    11161 gcaagggcat tttccacatt gtggctacct ggaacaccga tttcattcgc tgccatgact
    11221 acttcaccac ggaagtagag ttgaccatct tccagataag ctccatcaac cttttcaagt
    11281 gttgaaaatg gtataacagt ggcttctgtc ttggaagtca agtcttttgc caagtcttga
    11341 ttaaagttca agacaaggaa atcagctgct gtcatcttgt tctggatatt ccacttggct
    11401 gctacatatt ccgaaaatga cccatggtag tcgatatgag ttggcatgag gttggtaata
    11461 accgcaatct ctggatggaa ttcttgaaca cccatgagtt ggaaagaaga aagttccata
    11521 acaagcgtgt ccttatctga tgctatttga gcaacctgac tagctggata gccgatattc
    11581 cctgataaaa gaccatgttg gccagcagca gtcaaaactt ccccaatcat agtcgttgtg
    11641 gttgtcttac cgttcgatcc tgtgatacca ataatcggtg cttctgaaat caaataagcc
    11701 aattccacct cagtcaagac tggaattccc ttggccaaag ccttttcaat catgggattg
    11761 ttgtagggga tacctggatt tttcaccata agggcaaact cttcatccaa gagttccaaa
    11821 ggatggccac ctgtaatgac cttgatccct tcttccagca aactttgggc agctggattg
    11881 tcctcgaaag gtttcccatc atttactgtc acaatggcac ctagcttgtc caacaaacga
    11941 gctgcagatt caccagactt ggccaaacct aaaacaagga ctttcttatt tttaaattga
    12001 tctattactt tcatgtctcg aactccattt ctactcctac tattttacca tttttatgga
    12061 aataaaaaag ccacaaagtg tgtttgtgac tctttcttct aactgaatct taccatatca
    12121 tctatgtgat aaatcggtaa ctcgaatgac ctgatccact tgctcccaaa tcagaggatt
    12181 gtgggtcgca ataataatgg tccgattcgg attttttaaa gattctagga tggaaagtaa
    12241 ttcctcagag tttttggggt ctaaggaagc ggttggttca tctgcgagga tcaaaggtgg
    12301 atcctttaaa attatcttcg ctaatgcaac acgttgtgct tctcctcctg ataactcaaa
    12361 tataggttgc ttcaaatcca aataagagag gtttacacgg tttagagctt gtttcatcaa
    12421 agagattttc tctttttcct tcaacttttt accaactaaa cccagattga gattctcttt
    12481 gacggtttgg ctttcaatta agccaaaatc ttgaaataag tatcccaagt aatctctaaa
    12541 gaaaacagaa ggcttgatgt ccttaagaga agtaccatca tagatgattt gtcctttgtc
    12601 atatggctct aatcgtccaa tcatattcaa gattgttgtc ttaccacagc cacttgtacc
    12661 gattaaggca taaattttcc caccttcaaa atgaagattc gtatctgaaa atagctgacg
    12721 gcttccaaat tttttagata tattctttag ttcaatcatc ctattttcct ttcataattg
    12781 tcatagaaac acgagattct ttctgcgctt gacggtaaag cgtcaaaact gcactagcta
    12841 gaaagaccaa taaagtgagc aagccaatca ccaagtctcg actgcttaaa ataaagagac
    12901 tagcaccaaa tacaaaactg gcaaattggc taaccatata ctgagcatgt gtttcaaaaa
    12961 atcgtaaacc tgaaattcgt ttaatcaaga tatctcggcg gaattgctcg aaatatagaa
    13021 gattgacaga ataaaagagt aacaaggaac tggctattcc aacaatagct cctaagatta
    13081 aagttgctgt ttcagtttga acttcattat aacgagttag ataaacactt cttccttctt
    13141 taagatagga tacttgctca taaattccag ctttcttcaa gagttctagc ccactctcat
    13201 atcctttgat aaagagttgt tttccagcat tgatagacca actagataag gatataaaac
    13261 tatcacctgt agaagtcggc gtgaatacca ctaaaatcgg atcagtcaaa tactgagtgg
    13321 atacgggatt ctcaccgtta ttataaacaa accgcttttc tcccattgaa agataactaa
    13381 cgtgcgcttt catctcataa tccaaaggag cacttgcctc ctcaccagat tttccataat
    13441 aactcaatct ttcttcaaaa actttcttaa gttctgcttc tcgagagcgc aaatgttctg
    13501 ggagcaagag gataaactca cctttttgga gatgggctaa cttctgtttg gtctcagcat
    13561 ctaccacgac cttttccttg tccaaataac tgggactaac atagagcgta ttagcatctg
    13621 gactataggt atccagtgtc tctccctgtt cattttttcc ttgtggattg gcaaaatgga
    13681 gcagattatc ctttacataa agagcttgtt cttcttcgat tgcttccttg gcaaaggcat
    13741 accacttgct ctgattttct gtatcttttc ctctatcacc taagccaaaa gaaatttgat
    13801 aatagtctgc tctatcctgc catgcttgtt ttgaaatttc aagttctttc aatcgttggt
    13861 aagacgtcaa acctgtctta acagcgtatc ctactgtaaa gacagcaacc aactgacaca
    13921 atagggttaa aatcatcagg cgtttaaggg gtaatctccc cttaataacg ggaactaatg
    13981 ctttgtaatt caaactcatt agataaagaa gcattagtaa aattgaaatc gccaataaaa
    14041 acaacagata gaaactaatc ccaaaaccat aggtggctaa caagatagga taaaacaaac
    14101 cttgactaaa aagaacgact cccccaccta ggaaggaaag gagggctgat agaaggagcc
    14161 atttgatatc agtagataaa gaatgcccca tgatggataa gagagtctga ccagaaaaga
    14221 gttttatacc tgctgctctc atttccttaa tccgagtgat aatcactaaa gcaaagaaag
    14281 ataagccaaa tattgctaaa ctaattaaaa taaggggatt tagtaatatt cgaaaagcaa
    14341 gaaaataggg cggtatcttt cggtcagcac ttgctttata acccaaatct cctaatttat
    14401 cggcaagctt ttctttcgtc aaggagcctg acaaaaggag ataactattt agcggatcac
    14461 tacgttcacg actttcttgg ctagcttctt ggaattcttt tggtaaagtt ccctgaccat
    14521 aagttgcata agtaaagtga gtcgtcccat ccttactcgg ctctacaatt cttctagcta
    14581 ttaaactctg ttctgagttt gcaaaattct ccaattcctg ttcaaatacc tcacgcgtcg
    14641 gttcctgagt atcttttttg acacgaagta aagaaacgga atcatagctt gcatataaat
    14701 attgtggcgc acgtaagaca ataatccaag caaggaagaa gctgagaaaa aaagttgata
    14761 ataatatgaa tagtttcttc atagtagact ccttgtaaac aaaattcccc ctgtaatttc
    14821 ttacaagggg aacgatttaa atcaatgaac gattagtcat aatcacagta aaatgctact
    14881 tgttctcccc atttagtcca aatccatgca taggaggttt ttccagcagg agcttctcct
    14941 ttatcagaat gaccatccca tctgctcacg atggatgaat atatttttta ccatgatagt
    15001 aatttgaaaa agcccaacca cctcctgaac cttctccata tgtccatact cctccatctg
    15061 gatattgtac agcagctgat gcagctccca ataatgtaaa atttgaaata agagctagag
    15121 caagtaatct atgttttttc gttttcattt tattttttct ttcaaaaaaa gcacaccttg
    15181 agcaacaatg caacaaaata aatcctcctc tctcttttat tgaaaccgct ttcttatgtg
    15241 ataagaataa cttttttatt atttgttgtc aaggaaaaaa tcgaattttt tagatatttt
    15301 actatattac ctctgtgaat aatattatat agtagtttta tttcaaaata atatgcaacc
    15361 agtactaacc aaatataaaa tagatgccat taaagaattt tattcaagtt tttcccattc
    15421 atactataca agcaaaagag atggtgttaa ctaaaaagca attcaaacta ttgtaaaatt
    15481 cctagcaaaa aagagagcca aaactctctt ttttatcttc ttttactttt tttgactggc
    15541 atgagtgtga tgtctctcac actaaagtaa gctaggatca acatggctat tgctaggaat
    15601 atttctgttg gtaattgaaa aattttcaga aaagatagaa ccaataaaat caagagtgcc
    15661 actaaaatac ataccatagc gacgatattg acagtccctt taatgctttc tggtgtcgca
    15721 aatacataga gtaggagcag taaaattcct aggactaaat agaccatctt tctctctttc
    15781 tagctcttat tcagctgatt ttttcttctt gttagctttc tcacgctctg ctttgttaag
    15841 gatttgttta cgcaaacgga tagactcagg cgttacttcc atgtactcat cgtcgttcaa
    15901 gaactcaaga gactcttcaa gtgtcaagat acgaggcgtc ttgataacag ctgtttggtc
    15961 cttagtagct gaacgaacgt tggtcatttg ttttgccttc gtgatgttaa ctgtcaaatc
    16021 attttcacga gagttttcac cgatgatcat tccttcataa acctcagtac ctgggttgac
    16081 aaagatcgta ccacgttctt cgatagacat gattgagtaa gttgtagcct taccagcatc
    16141 gatagaaaca agggcaccac ggtgacgtcc accaatttcc cctggaatca atggcaagta
    16201 ttggtcgaag gtatggttca tgataccgta accacgagtc attgacaaga actcagttga
    16261 gtatccaatc aaaccacgcg ctggaacaag gaagaccaaa cgagtttgac cattaccagt
    16321 tgaaatcata tccaacattt cacctttacg ttcagaaagg ctttggataa cagacccttg
    16381 gtattcttct ggagtatcga tttgtacacg ttcaaatggt tcacatttaa caccgtcgat
    16441 ttcttttacg ataacttctg gacgagatac ttgaagttca tagccctcac gacgcattgt
    16501 ttcgataagg attgacaagt gcaattctcc acgtcctgaa acagtccatt tatctggtga
    16561 atcagttggg tcaacacgaa gggaaacgtc tgtttgcaat tctgcctgca agcgttcttc
    16621 caccttacga gaagttaccc atttaccttc tttaccagca aatggtgagt tgttgaccaa
    16681 gaaagtcatt tgaagagttg gctcatcgat gtgtaggatt ggaagagctt ctactgcatc
    16741 tatcggagtg atggtttcac cgacaaagat gtcttccata cctgaaacgg caatcaagtc
    16801 acccgctttg gcttcttgga tttcacgacg ttccaaacca aagaaaccga agagttttgt
    16861 aacacggaag tttttagttg taccgtcaag tttagaaagg gtaacttggt ccccaacctt
    16921 aactgtacca cggaagacac gaccgatacc gatacgtcca acgaagtcat tgtagtccaa
    16981 aagtgacact tggaactgca aaggctcatc tgagttatct actggagctg ggatatggtc
    17041 gataatcgtg tcaaagattg gtgccatagt cgcttcttgg tcagctggat catctgacaa
    17101 tgaagaagtt ccgttgatcg ctgaagcata aaccactggg aaatcaagct ggtcgtcatc
    17161 tgcaccaagc tcgatgaaaa gttccaagac ttcatccact acttctgctg gacgagctga
    17221 tggcttatcg attttgttaa caaccacgat tgggacaagg tcttgttcca aggctttttt
    17281 caatacgaaa cgagtttgtg gcatggttcc ttcataggca tctacgacca agacaacacc
    17341 gtcaaccatt ttcatgatac gctcaacttc tccaccaaag tccgcgtgtc ctggtgtgtc
    17401 cataatgttg atacgagttc cgttgtaagc aacggcagta tttttagcaa ggatggtaat
    17461 cccacgctct ttttcgatat cgtttgagtc catagcacgc tctgccaatt cagtacgtgc
    17521 atcaagcgtt tctgattgtt tcaataattc gtcaaccagg gttgttttac cgtggtcaac
    17581 gtgggcgata atcgcaatgt tacggatatc ttctcttaat tttgtcatga tttcctctat
    17641 aatattcaaa atttattttc taactgaacg attataccat aatttcaaat aaataacata
    17701 actcaagcaa gtgtaaatgt tttcactccg cttttctttt cacgtcaagc cttttcaaag
    17761 caagcgactt atgataagat aggcacagta tgcgtttaga taatttatta gcccaagaaa
    17821 aagttagccg aaaggccatg aagcaagcac tcctcagagg ggaaattcta gtcgatggtt
    17881 gcccagcccg atccctagct caaaatatcg atacaggact acaagaactc ctttttcagg
    17941 atcgaatcat tcaaggctat gaacacacct atcttatgct tcataagcct gctggtgtcg
    18001 ttacagccaa caaagacaag gaacttccga ccgtcatgga cctgcttcca tctgacatcc
    18061 agtctgacaa gctctatgcc gttggccgac tggaccgaga tgcaacggga ctcctcctct
    18121 tgaccgataa cggtcccttg ggctttcagc tcctccatcc ccaatatcat gtcgataaga
    18181 cttaccaagt ccaggttaat ggacttctaa cacctgacca tatccaagcc tttcaaaagg
    18241 gaattgtctt tttagatggt actgtctgta aacccgcaaa actagagatt ctatctgcaa
    18301 gtccctccct cagtcaagcc tctatcacca tttcagaagg aaaatttcat caaatcaaga
    18361 aaatgttcct ctcggttggt gttaaggtga ctagcctcaa aagaatccaa tttggggact
    18421 tcacattgaa cccagattta gcagaaagta actaccgccc tttgaaccaa aaagagttac
    18481 aaatcattaa aaactattta gagatgagtc gataaaacaa aaaaagcttt aaaactaaag
    18541 cttttttctt ttatttaccg aaaaattaag gcgattgcta caatccagtt aactacagaa
    18601 atcacaattc ctaagatatt aagaatcttt tctattttat agtctaattg tgactctttt
    18661 tggtatgaaa tagccaagac caatcctatg atacccaaaa tcaggcctac aattggaaat
    18721 aacaaaccaa gaataatcga caagataccc acaaaaagtg gatttttctt cttttctttc
    18781 atgttctaag aactctttaa attttataca aattaattat actataaaac aatagcttca
    18841 tcctatcatt cgactaattt ggaaataagg ttagctagtc ttcactttcc ctttccaaga
    18901 atccaagcca taagaaagga tataaatctc agaaaaacct tgttttttca agtaaagagc
    18961 tgcatttgta actcgttgcg cacgttggtt ttcgtagaga aggacaggtt tatctttacg
    19021 aagggctgca agactagttt tcaactgact tgaaggaata ttgcgtgcac caaggatatg
    19081 ttttctgtgg aattctgctg ggtcgcgcaa atcaatcaat tgacccgtac gaatcaaggc
    19141 ttcaaactcc tcattgtcca caattttagc cgcacggcga atacgaagat agttaaagcc
    19201 catccacgcc aacattgcta gtataagtgc ccacaaaatc caagtaacca ttagttcttt
    19261 tctccatttt tctcaatata atccaattct accttgtgct ctctgcgaag aactgcttct
    19321 gcctctagat agtctaattt atccatcaac cctgcatcgt aaatccgaga tagttccaac
    19381 ttcatcagtt caatatcata taagcgtttt cccatgtaaa caataatacc aaatcgtttg
    19441 aggaattgct gcacatcata gaatgttttc ataagactca ttctagcaaa attttgtgtt
    19501 tttttcaaga agagactcac acaatgctcc ttattttcct atcttcttta gcgattctaa
    19561 ggcaagtatg gtacaataaa aacatgagaa ttcaacaatt acattatatt atcaaaatcg
    19621 tcgaaactgg ctccatgaat gaggcagcca agcaactctt tatcactcag ccaagtctct
    19681 ccaatgcagt tcgagatttg gaaaatgaaa tgggcattga gatctttatc cgcaatccca
    19741 agggaatcac cttgacccgt gatgggatgg agtttctctc ttatgcccgt caggttgtcg
    19801 agcagaccca gcttctggag gaacgctata aaaatcctgt tgcccaccgc gaactcttta
    19861 gcgtttcgtc tcaacactat gcctttgtgg tcaatgcctt tgtctctttg ctcaagaaaa
    19921 gcgatatgga gaaatacgaa ctcttccttc gtgaaactcg gacttgggag attatcgacg
    19981 acgtcaagaa cttccgcagt gaggtcgggg tcctcttctt aaacagttac aaccgtgatg
    20041 ttttaaccaa gatgctggat gacaatcacc tgctagccca ccatctcttc acagcgcaac
    20101 cgcatatctt tgtcagcaag accaaccctc tggcaaagaa agacaaggtg aaactgtctg
    20161 atttggagaa tttcccttac ctcagctatg accaagggac gcacaactcc ttctactttt
    20221 cagaagagat tctttctcaa gaacaccaca aaaaatccat tgtggtcagt gaccgtgcca
    20281 ccctctttaa tctcttgatt ggtttggatg gttataccat tgcgacaggg attttgaaca
    20341 gcaacctaaa cggagacaat atcgtttcta tcccactgga tattgatgac ccgattgagc
    20401 tggtctatat ccagcatgag aaaaccagcc tatctaagat gggcgaacgc tttatcgact
    20461 atctcctaga agaagttcag tttgatagtt gagaaatgat aagaaccaat atgtaggcta
    20521 gcaacaacct gcacattggt tctttttact tataattaaa agtttcccct gccaacttat
    20581 cagctagctt gggaaagaga gtataaaact tatgggctag gttcaacaaa atcgggagat
    20641 tgagttctcg tttatttttg cctataatct tgacaatctt tttagccact gcatctgcct
    20701 ctaagaggaa gcggtcaacc gatttaagat aagttccatc tgggtcagct tggtcaaaaa
    20761 atcctgttcg gattggacct ggattgactg ttgtcacata gactccatag ggcataagtt
    20821 cgagtcgcag agcatttgaa aaaccaatag ccgcaaactt ggtcgctgag taaagactag
    20881 acttgccagt agctattaga cctgccatgc tgacgatgtt gatgatatgc cctttgctgc
    20941 tttccttcat acgagccgca aggtgacgag acagattcat cagggcaaag gtattgacct
    21001 caaacatctg gtgaatatct ttatcagcaa tctggtcaaa tccctcaaaa atcccgtaac
    21061 cagcgttgtt aatcaagaca tcaatcttgc catagcggag ataaagatca gttaccagag
    21121 cttctagggc tgaatcgtcg gtaatatcaa tttcaatcaa ttctgcatgg gaataatttc
    21181 cgtagagttg ggctaatttt tccttatttc taccaagcaa gatgagttgg tcattgggca
    21241 ggagtttgac catttcttga gctagaccac cgctagctcc ggtaatgaga atagtaggca
    21301 tacttatcct ttctgtgact gctagatttc cacttcttcc aagtctttga ccacatggac
    21361 attttcaaaa attgtggcag cgtctttctt gagtttgcta atatcttttg agaggaaacg
    21421 ggcactgata tggttgagta ggaggcgttt ggcacctgct tctaccgcta cttgtgcagc
    21481 ttgcatatta gttgagtgac catggttacg agcaattttt tcatcaccct tgccataagt
    21541 ggactcatga actaggacat ctgcattgac agccagacgc acactggcac ccgtttttcg
    21601 agtgtctcct aaaatagtga taatcttacc tggacgtggc gctgagatat agtctgctgc
    21661 cttgatttca gttccgtctt ccaaaacaag atcctggccg tttttgattt taccaaaaag
    21721 cgggccgaac ggaacaccag cagccttgag tttttcagca tccagcgtcc cttctagatc
    21781 cttttgcatg acacgatagc caacacagaa aatagtgtgg tccagctcct ctgcatacac
    21841 agtgaattta tcggtttcaa gaattttacc cagagaatct tggtcaaact catggaaatg
    21901 aatgcggtag ggcagacgag aacctgacac acgaaggctg gttaagacaa atgacttgat
    21961 tccttgaggt ccgtagattt ccaaatctgt ctgctcttca ttggcctgaa aggcacggct
    22021 agaaaggaaa cctggcaaac caaaaatgtg gtctccatgc agatgggtaa taaagatttt
    22081 gctgacctta cgtggtcgaa ttgtggtttc cagaatgcga ttttgcgtac cttctccaca
    22141 gtcaaagagc caaacttcgt taatctcatc caaaagtttc agggcgagac ttgaaacgtt
    22201 gcgggcttta gagggctgac cagcccccgt tcctaaaaat tgaatatcca ttcgatactt
    22261 tctaattaat caatatataa catggctgtg cggttttccg atcggaaata gcgtttgcca
    22321 gaaaaagcag cagcttcttg caataaatcc tcttggctgt agcctttgag acgttttcga
    22381 ccatcagcca atctttccaa atcagtcaaa gctgtgagac tttctaggct gataacttcc
    22441 tcgtcctcga caggcttcat gtaaatctta ccagactctt caaagactaa ttgatggggg
    22501 aaaatttgcg caatttcaaa gagcaagtca tccgagattt tctcctcatt ttcaaagaaa
    22561 atccgaccaa ggccgtcact ctcataacaa aaaccaaagg atttaccaga cagattaagc
    22621 cgaataaaag gcttattttc tagggtgaaa cttggctcag tattgtaaag attcagttcc
    22681 tgactgagtt ctgcaaaata atccgtcgca gcctgaggac tctttttctg atagagttct
    22741 gcaaagtagg cattaacaac acttggcgga ggtgtaataa gtgttaactg ctcctgatct
    22801 gttttaccag ctagaagctg atccagatag accttgtcca gacttgtata acctccatac
    22861 tttagagcca aagttttaat atcagtcata aaattcttct aacctccatt tatttttctc
    22921 ggaaatgtag cctgtaatca cttcgccgtc ttcctgataa tcacgttctt ccagaattgc
    22981 aacactctct aaatcatgaa tcttgtagga ctttgaaaaa ggcactcgca gggtaaatgc
    23041 ttcaaaaatt tccttaatct tatctagcaa taatgcttgc aagttttcac gactgtcctc
    23101 agacttggca gaaatgaggg tatatggcgt ttgggtaggc gtgaaatcct ccaccaaatc
    23161 cgctttatta taaagcgtca agtgaggaat atcttccatg tccaggtctt tcatgatgga
    23221 gagaaccgtt ttttcatgct cctcgtggta aggattgcta gcatcgataa catgaaccag
    23281 aaggtccaca tgcttgcttt cttccaaggt tgacttgaaa ctggacacca actctgtcgg
    23341 caaatcttgg ataaagccaa cggtatctgt caaagttact tggagattgc ctcccagatg
    23401 aatactcttg gttgtcgcat ccagagtcgc aaagagctca tctgcttcat actgggtctt
    23461 actggtcaag atgttcatga tagttgattt cccagcatta gtataaccaa tcaaaccaat
    23521 cttaaaagtg ctagactcca aacgtttttc tctgacagtc gcacgatttt tctcaaccac
    23581 cttgagctgg cgctcgatat ccgtgatttg attgcgaacg ctacgacggt tcagctccag
    23641 ctggctttca ccaggaccac gggaaccaat tccccctgcc tgacggctga gcataatccc
    23701 ctgaccaacc aagcgaggca aaaggtattt gagttgggct aggtggactt ggagcttccc
    23761 ttcatggctt cgagcccgca tggcaaagat atccaaaatc aactgcatac ggtcaatgac
    23821 cttaacaccg agaacttcct ctagattgac attctgcctt ggggtcagac gattgttgac
    23881 gatgacagta gtgatttctt ctgcatccac cataagcgca atctcttcca acttaccaga
    23941 gccgacgaag gtcttggaat catatttttc acgtttttgt ctgtagctat ctacaacgac
    24001 tgcccctgcc gttttcgcta aactagccaa ttcttccatg gagaggtcaa aactgtccat
    24061 accctgcaat tccacaccaa tcagcaggac tcgctcctct tttttctccg tttcaatcat
    24121 ctaaaaactc ctctatctgg cttaaaatgc ggtcttgtac accagattct ccaatctgat
    24181 aaaaggtgac ctgcatgcga ttacggaacc aggtcagctg acgcttggca aaacgacgag
    24241 tcgcctgttt aagactctca ctagcttcct ccaaggtctg ctctccacgg aaataaggaa
    24301 agagttcctt atagccaatt cctttagcag cctgtacatt aggggaatgg tcaaacagcc
    24361 acttggcctc atccaaaagc ccagcctcaa acatcaaatc cactcggtgg ttgatacgct
    24421 cataaagttg actacgttca tcatccaagc agataatcag cggttcatac aaggtctctt
    24481 gattttccaa atcctgacca aaatgggcaa tttctaaggc acgcatagca cgacgacgat
    24541 taaactgggg aatctcaagg cctgcttgat ccaccaaatg ggctaattcc tcatctgaat
    24601 atggctccaa actagctcga taagctaaaa tctcctcatg aggagtctcc ccacctaggt
    24661 ggtaaccttc tagcaagctc tggatataaa gtccagtccc accggcgata atggctagct
    24721 tgccacggtt gtgaataccc tcaatagtca tcttagcttc tgaaacaaaa tcaaaagccg
    24781 agtaagactc ggttatctct ctaacatcga ttaaatgatg aggaacagct gcctgctctt
    24841 ctggactagc cttggccgtc ccaatatcaa gtcctcgata gacttgctgg ctatctccac
    24901 taaccacttc gccattaaaa cgctttgcaa cttcaatagc tagagccgtc tttccaacag
    24961 cagtcggtcc aacaatcaca attatttttg ttttcatctt ttttccttga aaaattccca
    25021 ttttttcgtt actattatta taacacaaaa aggtcagtca gaaaaatgtg acctcttgag
    25081 gaggctggct gattgagaat ataaaggagg aagactcatg gctaaaggat tcgctaaagg
    25141 tcttgtaaca ggtgtcgcag gaactgtcgc tgccgttgca ggtgcagtat acgcatttaa
    25201 aaagaaagta atcgaaccag aagagcaaaa agcagctttc atcgaagaaa accgtaaaaa
    25261 agcagctcgt cgccgcgtat cacgttaaga aacaaaagaa gttgggatta ttctcaactt
    25321 cttttttcta ttcttttaaa tagctaggtc aaacttcaac tgtggcttaa cagggtcata
    25381 atccaccaac tcaaaatctt ctgctttgat atcaaagaaa ttagtcccat caggaacatt
    25441 taaaaccaag cgtggttggc agtttgacgg ctcccgacgg agcaattcct gagcttgttc
    25501 aaattgatta tcatagatat ggaggttgtt gatgaagtag aagaacttcc caaccttcca
    25561 gccaaaatgt ttggcaatca tcatctgcaa agccacatac tgcatagcgt tgatgtggtg
    25621 ggccaccagc atatcattgg agcgctgggt caaggtcgca tccagataga tttccccatc
    25681 aacacgccga acatcaaaca tggtctgaaa ggcgcacggg agcagcccat ctgtttcttc
    25741 gaaagcttgg taatcccaga gcgaaataat attgcggcgg ttccaaggat tggtttccaa
    25801 ctgtttgaga agcttattga taatgtcgtg tttcttaaca acggcaccat agcgctcacc
    25861 aatggttccc gtgtctccaa cttcccagtc attccagtag tgaacattgt acttgtcatt
    25921 aagcacttct aagctatttg actggtcttg gtaaatccag agaacttctt tgatggcgga
    25981 tttgattgca atgggacgca aggttgtgat aggaaattct cctttagata agtcgtactc
    26041 ggaaaaggca ccagttacat acttggaatt agcaacagtc ccatccttgt acttaggacg
    26101 agcctgctct gagaaaacac cttcctttag aatgcgttca atattctctt taaaaatcgt
    26161 atctgctttt gtcatttcgt ttcacctcat tcattgtcct aactagtata gcataaaaaa
    26221 taaaagagga acattactaa ctctaggtta gcattttcct ctctcattat cttattgcaa
    26281 tacaagtgat gctgctccga taactccagc gtcatttcct agagttgcaa gagctaattt
    26341 agtagatgtg cgtacttgtg ggaaactatt ttcatcgtaa actttttgaa caccttgtag
    26401 aaggaattct cccgcggctg acacaccacc accgatgacg attgttgatg ggtttaggat
    26461 tgaaccaatg ttagcacaag cgattcccaa gtaacgtgag aagttacggt aaacaatcaa
    26521 agcaaggtcg tctccttctt ttgcgagatc aaagacagtc ttagcagtta cttcttctcc
    26581 gttatcaatc aagcgtttca aggctgcatc gccttcgtat tcatcggcat agcgacgagt
    26641 caagttgaca atccctgttg ctgaagcaac tgtctcaagg cagccttttt taccacaagt
    26701 acatgagatt ggttggtcaa agtcaacagt gatatgacca agttcacctg ctgcaccagc
    26761 aacaccatga agcaatttgc cttctgcgac aataccacca ccaacaccag taccgagtgt
    26821 cataaagaca acgtctggtt ggttatctcc agcacccatc cagcgctcac caagagctgc
    26881 tacgttggca tcattatcga tgaaaaatgg aatgcccaaa gctttttcaa tcttttgttt
    26941 gattggttga agggttttcc agttcaagtt gtaggcaccg ataacagtcc ctttgtcacg
    27001 gtcaaccaca cctggtgatc ccattccaat gccttggaag tccgctgctg ccaatccaag
    27061 caagtccaaa cgatgttgaa tagactcaat catatcatca acgatatgac ttccctcatc
    27121 caaaatgttg gtcttgattg accattttcc ttggatttct cctgctgttg ttaagattgc
    27181 aaatttgata gaagttccac caaggtcaat cccaataatc ttttgactca tcatattctc
    27241 ctttttcatt gtgtagtaat tgaaaatgct tacagtacta gtatatcaaa atccattcac
    27301 ttatgcaaag gtttgcgtaa atgaattata aggaattttt tcgcctacca gtatctgtta
    27361 atcatctaaa tgatcaatgg catattgagc tgcatcattt gaaaatttat caaaatcaga
    27421 agttaattgt ctatacatac gtttttttga catgtggaat aacgaattat aactttttgc
    27481 ctttcctaaa gcagcagaat attcactatt gctatcatta ctagaagaaa ctgtacttgc
    27541 ttgaccttcc ttccaaactc cgtcagcgcc aacataataa cgtccaccat caacccattc
    27601 attgacagcc attttaccat ccgattttag atagtaattt ccttgccatg tactgtaagc
    27661 ataagaacca tctgatgtca aataatacca agcttgatag gtggcatcat aaacccattc
    27721 acctttagcc attttaccat ctgatttcaa atagtagttt ccttgccatg cattgcgagc
    27781 atatgaacca tctgatttca agtaatacca tgcttggtaa gaagaatcat aaacccactc
    27841 accttgtgcc attttaccgt ttgatttaag gtaataagct ccttgccatg cattttttgc
    27901 ataagaacca tctgatttca aataatacca agcttgataa gaagagtcat aaatccattc
    27961 actctgtgcc attttaccat cagctttcag gtaatagctt ccctgccatg catttttcac
    28021 tagatttcca tttccatcaa agtagtacca agcgccgtcc tgcttaaccc aaccacttgt
    28081 tgttgctgaa cttgtgttga tttgaatagc cgttgactgt tttgctttaa aagcaccctt
    28141 aggagcattt ttcaattcgc aagccacacc atcatgatca cggtctaact tggcagaata
    28201 accaggttct ccctcgtgaa tatccgaata gccattcgcc caagcttcct tacagctcga
    28261 aaaatggatg ttttcttccg ccaaaactgg ttgtgaaaac aaggctaaaa ttggcaacgt
    28321 caccagactc atttttaaaa atagacgttt attcatttct ttctcccata attatgatat
    28381 cgatttcaat attattttat caaacttatt tcagcaattc aaggaaactt ctggtctttt
    28441 ctacaaactc ctttggtttt gccttattca agacatgagg gccatcagga atgatctgaa
    28501 actgcgaatc tgttaacagt ctatggagag ctttcataga actaagattc ggtttatctt
    28561 tgctgccaca aattagtaag gttggatagg agcaagtccc tgctatatcc gttaaatcaa
    28621 gtgtcttcaa ttcctcagaa actccgacca taagagtctt gtctgctccc tgtttttcaa
    28681 atactctttt gggaagtagt ttaaaaatca gcaactgaag ataaaatagg atattccctg
    28741 ctaatttaag cgggcatcct gacagaatca aagctcgaag atttggtaaa tcgtaactgg
    28801 aaagttctag tgtcagggca gcacctaagg acaatccaat caaaacaaaa ggttctgtct
    28861 cttgagctag gtgctgataa actcgctctt tagcttgttg atagttacta actccagaag
    28921 gaaataactc gatagcctca gaaggataat ctgtcagtag attccgaact tctttccaag
    28981 actctgctga ctgccctaac ccatgcaaaa atatcaattt catctagttc tcctcaaggc
    29041 ttagttcata caagcctctc actgcattac agccgtaaat agcttctgct tgggttaaat
    29101 ctgccaaggt caagactttc tcttctacct gtcctgtttc tagcaaatgc tgacggtaaa
    29161 ttcctggcaa gattccaagt cggataggcg gtgtgtaaag ttttccagcg attttcagaa
    29221 ccaaatttcc tatagaggtt tcaagcagtt ctcctgactt attgtggtaa atcttctctt
    29281 gttctcctag gctcaaatgc ggtcggtgag tggttttaaa gtaggtaaag gattgattca
    29341 aagcagcttc ctgaagacag acttgggcct gacaaaagct tgtactgaga ggggttaata
    29401 cttgacgatt gacttctatc tctccagatt tgctaaggct gattcgcaag cggtaatctc
    29461 gattagcttc acaatcctga cactcttcct caatcttgtg tcccaagtct tctgcatcaa
    29521 aaggaaaagc aaaataacga ctagcttttc tcagtctttc cagatgttga tcttcaaaca
    29581 gcaggttctt ctggctgatt tcccctgtcg taatcagttg gaagcgagct tgtttacgat
    29641 aaagaactgc tgccttttga tgaacctctc ggtattcaga ttcccatgtg ctatcccaag
    29701 taatccctcc gccaactcca taaatggctt gacctttgtg aagttgaatg gtacgaatgg
    29761 ccacattaaa aatccgtcgt ccatttggaa gcaagagacc aatcgttcca cagtagactc
    29821 cacgcggttg aggctccaag tccttgataa tctccattgt cgcaattttc ggtgcacccg
    29881 ttatggaacc acaaggaaag agtgagcgga agatttcaac aaggtccaca tcctctcgca
    29941 actgactctt gatggtcgaa gtcatctgcc aaacagttga atactgctct acctgacaca
    30001 gacgctccac gtgctcgctc ccaacttcag aaatacggtt catatcattg cgcaagaggt
    30061 ccacaatcat catattttca gagcgatttt tgggatcctg ttccaaccaa ctggcctgtt
    30121 caagatcttc ttggtcagtt accccacgct gagtcgtccc cttcattggt cgtgttgtca
    30181 actcgcgatc attttgctca aaaaagagct ctgggctcat ggaaatcact gccatctcgt
    30241 catgttccac gtaggcattg tagcccgcct cctgctctac caccatacga ttgtagatgg
    30301 caaaaggatt ggcacttaac ttttgcttga gttggacggt gtagttgacc tgataggtgt
    30361 ctccctgcct caagtgatgg tgtatctggg caatggcctt ttcatagtct gctgcagacg
    30421 tcacttcctg ccaatttgag ggcaaatcaa tatcctcata agtcagagga acaggggagg
    30481 tctctaccct atcgtgaaca gtaaagtaaa gcaagtactc gcccagtaga ggaaccttgt
    30541 gaactgttaa tttctcctca aaagcaggtg cagcctcgta gctgacatac cccaccacat
    30601 aataaccttg ctcttggtag ctttccactt gtgccagcaa atctgccact tcttctacat
    30661 ttctcgtttt caactcttta ataggctggg taaaggtata tctctcccct aaagtcctaa
    30721 aatcaatcac tgtttttcta tgcatacctt aagtatagca taaaaaggca gatacagaca
    30781 aagctgatct acctttttac gattttattc attctatgct tgtggtgcag taaatagatc
    30841 accagagaaa ccgtctgatt cttttagtaa ttgtttaaag actttttctt ttaatgcaac
    30901 agtatgtcta tatttatttt taattgtttg attagacaat tcatttaaat ctttttgtac
    30961 tgcttcatta aataattctt ttaatctagc atatgaatta atagtattac catcaatttc
    31021 aattgctgtg aatccttttt gcgctttttc ttttacttgt ttaaaccatt ctattttcca
    31081 ctcttcaaga gtagtaaatt tatctccaga aaccttcttg ataatatatt tatcacttaa
    31141 attattttca ccagcttttt tggattcatc tttatattta ttagaaacat atccgatgaa
    31201 tccattctcg tatccgaagt atccccacat acggaatgcg ttgtgtttga atgatagagc
    31261 acctggtgca ccatcgctgg tattaccacc atagataccg gacatcatat tgacattaac
    31321 atatgctgaa tttggaacaa aatcttcagg gcggtatcta ccattcccta caccatgttt
    31381 agttgcaaag ttgttctcaa ttagatcatt gattgttgtt aaagtttttg ttttttcttc
    31441 atcatttaaa tcacgaacaa gatcccattg gttaggctgt actaaatttt tgttgtattc
    31501 atcttttgta cgatattgtt tatctacttt tttaaaccac acgctattat cttttatatt
    31561 ttgagataag accgcatcag cttctagatg atctaacatc ataagtgctt cattgtaatt
    31621 cttcatataa tggttaattt catctcgtga ttttaattta ttaggattat agttatacca
    31681 ttggttaccg tcgttttctc tttcgaatgc catattcaat cctaaggcac catattcacc
    31741 ttgatgacct tcagttgcag gtgattgtag cataccttga gcgaacgctt caacgaatgt
    31801 accttcacgg tgaccatgac cgccataata tgctacacgg tcattaacgt gagtcgtttc
    31861 gtgtgtaaat gccgacgccc catattcagt aagcatatct gacataacga atacaacttt
    31921 gtgacgattg tcatttttgt tgtcgtagta agttgcataa gctccggcaa cagcaccatt
    31981 atgcccataa tattcaccga ccggtccata taattctcga actggagcgt aaattccctt
    32041 accatcatca aagttaccgt atctatccat ccaagatggc cacttatgtc cccaaacttt
    32101 ataaccttcc caaactgggg ttacgatatc ttttgcaagt ttacctttga cttcatcagt
    32161 tgctagacga taccagaagt caagatagtt gatgtgtcta ctagcagcaa gatctatatc
    32221 atttttcaca tcagccattg atttaccata cttattagca gtaccgaatg atattgtatt
    32281 gtatgttgaa atcaagaaag cctctgtatt tgttaagttt aaaagaggaa gaatcatctt
    32341 ctggtggtac cctttagata ggttgtcaaa tgctctatat ttagcgtttt taagaccttc
    32401 ttcacgcgat tgtttttcaa caacataaac tttaccattt gtagaatgga taaaccaatc
    32461 gtttatatct ctatctggag taagtagttc catgttatat ttaaggaagt caatcaagtt
    32521 tccagaacga gtattttttg caagaacctc tctaaatgaa tcttgagtac gatgaccacg
    32581 taagttattt tctttagaac caatttcgat aagtctatcg attaagctaa cattattacc
    32641 atagaaatca ggcttaaaca tcataagctg tttaatgttg aaatcaccga atttaacacc
    32701 atagtaacga tttaagaatg ctagacctaa cataagttta gctttattgc cttcgatttt
    32761 cttaattaac gcacgttcag tatcttcatc ggtatttaat tggtgatctt cattttcgat
    32821 aagttgttta acaatagcag atatattatt tttaacttct gtaacacttt cttctaaata
    32881 taaatcgcga atgtagttat tttgtcgagc ttcactattg gcgtttttat ctttactcgc
    32941 gtctcgttta tctaggattt ggcgtacttc aggagattgt aattcaaaag aagatagttt
    33001 ctcagtgatg ctagcagcta gattatcacg atttttttcg actatatttg gtgtataaac
    33061 aatatcatct aatccttcga tactatattc acgaacttgt tgtacttgag attctttctg
    33121 tgcaatagct ttaatttcat ttgttttatc tgcatagtga atcataatgt gatcagcatc
    33181 tgaaagatca gtaacaaagt tgttgccttt catacctgta acagataata cttctttagt
    33241 tagtaagttt gagccggctg gaatcttgtt accttggtct acaatccact ctttattgta
    33301 gaatggttga agtttttcga tattacggta agcaagttcg cggtctgctt tgtaatcttg
    33361 agtatcttta taagtatcag cttttagttt gatgttgtta agcttttctt caataagagg
    33421 tttaatttca aatttatcgg ctgtaattcc gaatgattct attttcttgt tggcttcttc
    33481 taagctgatt tcttggattc tattagaacg agaatatttg aatgaatgag caccttcgct
    33541 aaccccttta acaacatagt ttcgatctat ccaattatgt gtatattccc cattttcaac
    33601 ctcaagatct ctagagccat aaaattcttc tccattttca actttcatca ttgtgacagt
    33661 attaaggata cgcccccaaa tccagctttt actaatgaag ccaccaacct cgacaggggt
    33721 cgttacttta atcgttcctt taacaacagc ttcactagtg aatgcatatg tattaacacc
    33781 gtttggatca taaccgttat cggattttgc aacaagacca cctacacgtg ccttatttcc
    33841 tacaatatca gcctcaacat aagctttttt gatattaccc ctccatactt caccggcaat
    33901 accacctata tctgagcctt tattacctac accagtaatt ttaccaatat aagcaacatc
    33961 ttgtaacaaa ccacctgtat caactttatt cacaatacct gcaactccat ctttaccaag
    34021 gatattacca gttactttaa ttttctcaac agtagcgttt ttaactactc gagcaagtgg
    34081 agagatatca ttaatccaag gcatgtttat atcaacatta gctaagttaa tattcttaac
    34141 tgaaccgcct tctatagaac taaataattg acgagccatg ttgtgaattg aatattgctc
    34201 accttcaaca ctacttaaat gacctctaaa tactttaggg acatattctt tatatggagt
    34261 tggtacattt gcagcattaa gatcagaacc aagtttgaat gtaccgttag gattatcatt
    34321 catggcatta actagttcat tgaagtcata gtaaacatta tctttgtgta cttttttctt
    34381 agcgatgtag tgagtataag ttttacccaa tttattagct gaatcacgtt ggattaaatc
    34441 aggagcaata gcagtaactt taaataaagt tttaccacct tcttctactt cttcaatctt
    34501 atcaacagca agtcttgtta ctttgttatc atgagttgag atttttaaat agtatgatgt
    34561 aatatctgtt ggtttttctg ataataaact tttatctgtt tcgttaccat caggatcaac
    34621 acttattaag cttgtttctt taatattttt aatttcaact tttttaatgt ctaattgaat
    34681 tggttgagca gctaatgttt cagtttcttc ttgaccatta cctctatcat aaaccatagt
    34741 agtagataga gtatattctt tgaaatactc tagattttca aatgcagcgc ttatagcttc
    34801 attatttaca tcatcacctg taagaactac agtattaaca acttcctctc cttttttcag
    34861 agttgcagtt attgatttta tttgagtatt tgctggattt tccaaagtat acgtgaccgt
    34921 aacttttcga tctatgtctc tcttttcaat agatagagtc aaacgtggct tttcagacaa
    34981 ttcaaccaat ttttcaatag ttgcagttaa tttttcaaca gcttcattaa cttcactttg
    35041 tttagactcg ttagtgttta cagattttgc tgctgtaaga actgtttcta actctgccca
    35101 tgtttgattt gtatagttct ctttattttt cttggtagct gtatcgatag cgcttcccaa
    35161 agctgttttg tcaacagata agtcagcaag ggctgttttc aaacttttct ctgcttcgtt
    35221 tatttgttct tgggtcgctg ttccgttatc ttttacttcc tgagctttat ttttagctgt
    35281 actcaaaaca gtccaagatt ccatgctgaa atcagtttca gtttttccct gtgcaatctt
    35341 aagttgattt tcgagttcaa ctttatctgt atttaatcca gaaattgctg ttttaagact
    35401 tgcagtctca gaatttactt cactttgttt agcatctgta ttagctgcaa ctttttcagc
    35461 ttctgtaacc ctagtttgga ggttttgcca acttctatca ctgtaatgtt cttttacctt
    35521 tgtttttgca tctgcaatcg tattgtttaa ttcagtttta tcaacgttta gagcgtcaat
    35581 agccgtttta agtttatttg tctcgctatt tacctcaggc tgttttacag gctctgaagc
    35641 atagacacct tttgcagttt ctaaaacagg tccaagagca ttgtaacttg ctgtagaata
    35701 atcaatagga gaaactgaac tagctttatc aatttgatta tttaactcac ttttatcaac
    35761 tggttcttta gtaccaatac cctttatttt atcttctggt ttcggtgttt cctctacagc
    35821 cttctcttct tcaggaactt ctggttgctt ttctggctca actggtgccg ttggtgcctg
    35881 ttcgtcttct cttggcgcga ctggttcacc tgcttgttca acttttggtt cctctgttgg
    35941 ttctgtttgt ttttctacag caggcgtttc aacttttggt tgttcaacag gttgattaac
    36001 agtctcctct tttgattcta ctggttcttc aaccttgatt tctggggctt ctgctggctg
    36061 ttcatcttct tgtttcggtg tctcttccgc tcccctatct tctttagaat tgtcttcttg
    36121 tgatgattct tttggtgtac ttggttgctc agcttgtgta ggttgcacgg gttgttctgg
    36181 gacttttgct tgttctactg gtggttcaac ttttgattcc tcagctggtt tgtctgatag
    36241 ttgactttct ggcttaactg ctactttttc ctctgatttt gactcaactt ctccacctac
    36301 ttcttcaact ggagctggtt ctgctgaatc ttctttcccc tcttctactt taggaagggt
    36361 gtcgtcagta ggttttacct ccgattttgg ttcttccttt ggactttctt ctgttttagg
    36421 tgcttcttct tttggagctt cctctgtctc tactacttgg ttttctgtcc tagcttgctc
    36481 ctgatttgtt attgattgag gagtctcaac ttcgactaca gtcacctctc caggttttgc
    36541 tgaggtttct tctaaaacag tgtccaagcc aagcgttttg aggatgtcac ctgatagata
    36601 accaacatag cgatagccct ccatttcaac aacaccctct cgactagcca gcgctagggt
    36661 cgcaactggg tctacagccc ctgcactagg aagaactacc aatcccatag ctccaactag
    36721 aaagacgcta gcaattttct ttctcttgta gattaaaagc aagctcccaa cagtcagcaa
    36781 accaaaagct gtcaaaacag atgcttctgt tcctgtttga ggcaactgat ctttttgata
    36841 caccaaacca tatacaactt cattcctgtc aggctttcct gtctgaatta aatctttagc
    36901 ttcttgtgaa ataatctctt tatttacata gtgataggta gctgcgtcca ctacagaagg
    36961 agccatcaaa aggcttccaa gaaatacaga gcctacaact cccttaatct tacgaattga
    37021 aaaacggtct tttttaaaca cttttatctc ctttattcat tctcaagact ttctaatagc
    37081 atcttgagga tagtgcgcac gcgcacctcc gattaatttt ggacgactag ccagtgccgt
    37141 tacatgggca tgaccaatct ctctcaaaat agggcgaatc ggaacctgaa catgcttgac
    37201 atgcatgcca attgcagtgt ctccgatatc caatccagca tgagccttga taaattcaac
    37261 ctcaactgga tcctgcataa acttaaaggc tgccaactgc cccgaacctc ctgcatgaag
    37321 agtaggatgg acactgacaa tttccagacc aaactgctct gccacctgac gttcaacaac
    37381 gagagcccga ttgacatgct cacaaccttg aactgctaaa tggatacctc tactacctag
    37441 aatacccaag atagtctcca ctatcagctc accaatctct tgactggatt ctttcccaat
    37501 ctgaccacct agcacctcac tagaagatag acctaaaaca aaaaggaccc cctgcttcaa
    37561 attggtcttt tctaaaacat cttccactac ctgacgtgtt tctctttgaa tctgtgtctc
    37621 gttcatctct gttacctctg ttgtcactct tctatcatac cgttttttct tgtttttagc
    37681 aagatagaca acctagaaag tttgcccaat tacgcataaa actcccagaa ttgactggga
    37741 gttagctagt ttctattcta tttatatata tttcaacttt cgtccctttt tggggtctag
    37801 aatcaatctt catctggtaa ttggctccaa aatgaagttt gagccgttga tcgacatttt
    37861 gaagaccaac tcccccacgt ttgagttgac tttgactact atcaccagca tcttggaagc
    37921 caacgccatc atcctcaata cggatgacca atcccgaatc ctgtttctgg acagaaagtt
    37981 taatatggcc ctgaccttcc ttttccttaa tgccatggta aagagcattt tctacaaggg
    38041 gttgtaggac cagcttgggt aagactaaat tatcaaaggt aacattttca ttaatttcgt
    38101 attccagctt atctccatag cgttgtttct ggataaagag atactggcgg acatgattga
    38161 tttcgtcaga gagacaaatc aagtccttgc cttgattgag cgccaagcgg aaataggttg
    38221 ccaaggactt ggtcacctgc accactcgct gactatcatg aaattcagcc atccagatga
    38281 tggtgtccaa agtgttatag aggaaatgtg gattaatctg gctcgaaagg gcttgaagtt
    38341 ggtactgacg ggtcgtttct tcctggctac gaatagctac catcaactga tcaatctgat
    38401 ccaacatggc attaaattgg cgagttactt ctctcagttc ataggcacca acttccttgg
    38461 cacgaagatt ttgagcacca gaagcaattt ccaacatggt ttctctcaaa tccttcaaag
    38521 gagcaatcca gcgtttaaga ctgaaccaca ctaagcagag acagacaaga agagatgtga
    38581 cactggcccc aagcaaggtc cacaagagct gactccgaac ctggtctaac ttttccaatg
    38641 atgacacgcc aagtaccgtc caatcagttc ctgcaatctt ctcttgactg acgtaggatt
    38701 tgtgaccagg agtataaccc tgacctgtat cgatgtaggg tttcatagcc tccattttgc
    38761 tagacgaact ataaactgtg tgttgaggat ggtagacaaa ttcatggttt tcattgataa
    38821 tgaaggcaaa gccctgctgc cccaactgga gttgattgag ataggcttcc agagtttcat
    38881 aagaaatatc caaacgaagc acaccaagat tggctccctt tgcatcaaca agttcttgag
    38941 tgacagaaat gacccactga ctatctgatt tacgagctgg agtcaaaaca ggcatagctc
    39001 cctgatgaat ggccttttgg taccaatcct cagccatcat atcagaggaa gttttcatct
    39061 gcacactgtc atctgtagaa atgacctgac cagatttggt caccagcaca acagttttca
    39121 agtccttatc tgacttcaag atggtcaaaa acaaatctcg gattccctcg accttgtctt
    39181 gactgggatt ctcagcatag gccagaacat ccgtctgctg ggtcaaaccg gtcgaagtgg
    39241 tttctagttt tttgatataa gactgaataa agtggctagt ctggctgatg gtcgtttggc
    39301 tgttgccctc aatggtggcc tcaatggctg aagaacttga ttgatagtag aaagttccaa
    39361 ccagagctag gagaatgaga aagaccagaa agatggaaat aaccattcta actaaaagag
    39421 aagaacgctt catcggtctt ctcccttctt aaactgacga ggtgtcacac ctgcaatctg
    39481 cttaaaacgt tgggtaaaat agttcatatc ttcaaaacca accttctctg cgatctcata
    39541 aatcttcaga tctgtagtta aaagcaagag cttggcttgt ttaacacgtt ctctcaccag
    39601 ataatcctga aaaggcaagc ccaactcttt cttaatcaag gaactcagat aggtcggact
    39661 aaaacctaag tcactggcta aagactttaa actaaattgg ctatcagcca gatgagactg
    39721 gattttctgg gccatgtttc cttcaaacct attagtcaat aaatcttgta actgctcttc
    39781 tttctcttcc ttgtctagtt tttgtttgat tttccccaac atttcctcaa tatcctgacg
    39841 agaaaagggt ttgagcaggt agtcgtccac acctagtttg acagcagaca aggcataatc
    39901 aaaatcatcg taacctgtta aaaagaccaa atgaacctga ggataggttt ctcgtaccag
    39961 actggccaac tggatgccat ttagatgagg catgttgata tcggttaaaa tgatatctgg
    40021 cacctgcttt tggatcaatt cccaagcctg ccttccattt tcagcctgac cgatgatttc
    40081 catatcgtag gctgctacat tgaccagttt agtcaaacct tgtcttacca gatattcatc
    40141 ttctacgatt aagattgtgt aggtcatgat ctgctccttt accacttact agtatcagta
    40201 tagcaaaatt ctcctctaac tgcttaggaa agacctctta tactcaataa aaatcaaaaa
    40261 gtaaactagg aagatagcca caggtttctc aaagtaccgc tttgaggttg tagata
//
LOCUS       DAVMAH010000014        38457 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVMAH010000014 DAVMAH010000000
VERSION     DAVMAH010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.014"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..89
                     /locus_tag="VYO94_000672"
     CDS             <1..89
                     /locus_tag="VYO94_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV1759339.1"
                     /translation="EPMAQQVIPKAAFGYIASGAEDTFTSFQ"
     gene            216..1706
                     /gene="lysS"
                     /locus_tag="VYO94_000673"
     CDS             216..1706
                     /gene="lysS"
                     /locus_tag="VYO94_000673"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV1759340.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            2331..3467
                     /gene="lctO"
                     /locus_tag="VYO94_000674"
     CDS             2331..3467
                     /gene="lctO"
                     /locus_tag="VYO94_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV1759341.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      3719..3807
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            4022..4690
                     /locus_tag="VYO94_000675"
     CDS             4022..4690
                     /locus_tag="VYO94_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV1759342.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            4934..5716
                     /gene="thiM"
                     /locus_tag="VYO94_000676"
     CDS             4934..5716
                     /gene="thiM"
                     /locus_tag="VYO94_000676"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1759343.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALSVSPAMSEFPA
                     DLEDLLKYAGGLLVNIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            5718..6347
                     /locus_tag="VYO94_000677"
     CDS             5718..6347
                     /locus_tag="VYO94_000677"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1759344.1"
                     /translation="MFHKELLKLYFICGTTTCQGKDLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      6556..6644
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6906..7466
                     /locus_tag="VYO94_000678"
     CDS             6906..7466
                     /locus_tag="VYO94_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1759345.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            7467..8852
                     /locus_tag="VYO94_000679"
     CDS             7467..8852
                     /locus_tag="VYO94_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759346.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRSLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            8854..9504
                     /locus_tag="VYO94_000680"
     CDS             8854..9504
                     /locus_tag="VYO94_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV1759347.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            9515..10207
                     /gene="tenA"
                     /locus_tag="VYO94_000681"
     CDS             9515..10207
                     /gene="tenA"
                     /locus_tag="VYO94_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV1759348.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            10212..10736
                     /gene="thiW"
                     /locus_tag="VYO94_000682"
     CDS             10212..10736
                     /gene="thiW"
                     /locus_tag="VYO94_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV1759349.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            10736..11539
                     /locus_tag="VYO94_000683"
     CDS             10736..11539
                     /locus_tag="VYO94_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1759350.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTSPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            11532..12164
                     /locus_tag="VYO94_000684"
     CDS             11532..12164
                     /locus_tag="VYO94_000684"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1759351.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(12373..13164)
                     /gene="thiD"
                     /locus_tag="VYO94_000685"
     CDS             complement(12373..13164)
                     /gene="thiD"
                     /locus_tag="VYO94_000685"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1759352.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(13248..13346)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            13530..13925
                     /locus_tag="VYO94_000686"
     CDS             13530..13925
                     /locus_tag="VYO94_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV1759353.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            13936..14307
                     /locus_tag="VYO94_000687"
     CDS             13936..14307
                     /locus_tag="VYO94_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV1759354.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFSFACGMNMMHGKMIVE"
     gene            14317..16560
                     /locus_tag="VYO94_000688"
     CDS             14317..16560
                     /locus_tag="VYO94_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1759355.1"
                     /translation="MTEIVKASLENGIQKIRIQAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSICTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKKNAKLAISQLKKRGLGTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            16767..18542
                     /gene="spxB"
                     /locus_tag="VYO94_000689"
     CDS             16767..18542
                     /gene="spxB"
                     /locus_tag="VYO94_000689"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV1759356.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            18653..19000
                     /locus_tag="VYO94_000690"
     CDS             18653..19000
                     /locus_tag="VYO94_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1759357.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(19117..20181)
                     /locus_tag="VYO94_000691"
                     /pseudo
     CDS             complement(19117..20181)
                     /locus_tag="VYO94_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            20316..20612
                     /locus_tag="VYO94_000692"
     CDS             20316..20612
                     /locus_tag="VYO94_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV1759358.1"
                     /translation="MDTPDENGYVADNYRITYLEAHIKAMRDAIYKDGVDLFGYTTWG
                     CTDPVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIDSNGASIG"
     gene            20733..21677
                     /gene="manA"
                     /locus_tag="VYO94_000693"
     CDS             20733..21677
                     /gene="manA"
                     /locus_tag="VYO94_000693"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV1759359.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLCSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(21668..23173)
                     /locus_tag="VYO94_000694"
     CDS             complement(21668..23173)
                     /locus_tag="VYO94_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEV1759360.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSAIGLDSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALVAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIICRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMSFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSWSSSPNLCNQKDLSNELRPFLFYG"
     gene            23256..24005
                     /locus_tag="VYO94_000695"
     CDS             23256..24005
                     /locus_tag="VYO94_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1759361.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSEKGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(24025..24480)
                     /locus_tag="VYO94_000696"
     CDS             complement(24025..24480)
                     /locus_tag="VYO94_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1759362.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(24500..25675)
                     /locus_tag="VYO94_000697"
     CDS             complement(24500..25675)
                     /locus_tag="VYO94_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1759363.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVNGGEVLSLDVLPQLSEKNLVTFLEKNREKS
                     LKNALKTLLPERLAEFFVQRYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(25734..26579)
                     /locus_tag="VYO94_000698"
     CDS             complement(25734..26579)
                     /locus_tag="VYO94_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1759364.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            26704..27261
                     /locus_tag="VYO94_000699"
     CDS             26704..27261
                     /locus_tag="VYO94_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1759365.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            27280..27747
                     /locus_tag="VYO94_000700"
     CDS             27280..27747
                     /locus_tag="VYO94_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV1759366.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLIIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            27836..28465
                     /gene="upp"
                     /locus_tag="VYO94_000701"
     CDS             27836..28465
                     /gene="upp"
                     /locus_tag="VYO94_000701"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV1759367.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            28639..29229
                     /gene="clpP"
                     /locus_tag="VYO94_000702"
     CDS             28639..29229
                     /gene="clpP"
                     /locus_tag="VYO94_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV1759368.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            29308..29556
                     /locus_tag="VYO94_000703"
     CDS             29308..29556
                     /locus_tag="VYO94_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV1759369.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            29658..30818
                     /locus_tag="VYO94_000704"
     CDS             29658..30818
                     /locus_tag="VYO94_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1759370.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            31086..31955
                     /locus_tag="VYO94_000705"
     CDS             31086..31955
                     /locus_tag="VYO94_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1759371.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            31959..32915
                     /locus_tag="VYO94_000706"
     CDS             31959..32915
                     /locus_tag="VYO94_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1759372.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            32915..33679
                     /locus_tag="VYO94_000707"
     CDS             32915..33679
                     /locus_tag="VYO94_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759373.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            33679..34389
                     /locus_tag="VYO94_000708"
     CDS             33679..34389
                     /locus_tag="VYO94_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759374.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            34748..35404
                     /locus_tag="VYO94_000709"
     CDS             34748..35404
                     /locus_tag="VYO94_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1759375.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            35512..36607
                     /gene="prfB"
                     /locus_tag="VYO94_000710"
     CDS             join(35512..35583,35585..36607)
                     /gene="prfB"
                     /locus_tag="VYO94_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV1759376.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            36625..37317
                     /gene="ftsE"
                     /locus_tag="VYO94_000711"
     CDS             36625..37317
                     /gene="ftsE"
                     /locus_tag="VYO94_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV1759377.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            37310..38236
                     /locus_tag="VYO94_000712"
     CDS             37310..38236
                     /locus_tag="VYO94_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1759378.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
BASE COUNT        11567 a         7182 c         8405 g        11303 t
ORIGIN      
        1 tggagccaat ggcgcaacaa gttattccta aagcagcatt tggctatatc gctagtgggg
       61 cggaagatac tttcacttct ttccagtgat tttagcgtca ggttcttttt agtttttaaa
      121 gattatccgt gaatttcttg cttatttatg ataaaatggg gtatcgcaaa aaatgactca
      181 tcgtattcaa ttttgagtaa aactaggagg atcccatgtc tacagaacat atggaagaac
      241 taaatgacca gcagatcgtt cgccgtgaaa aaatggctgc gctccgcgaa caaggaatcg
      301 atcctttcgg aaaacgtttt gaacgtactg caaattcaca agaattaaaa gataaatatg
      361 ccaacctcga taaagaacaa ttacacgata aaaacgaaac agctactatc gcaggacgct
      421 tggtaaccaa acgtggtaaa ggaaaagttg gttttgccca ccttcaagac cgcgaaggcc
      481 agattcagat ctacgttcgt aaggatgctg tcggtgaaga aaactacgaa atcttcaaaa
      541 aagcagacct tggtgacttc cttggtgtcg aaggtgaagt gatgcgtacg gatatgggag
      601 aactctctat caaggcaacc cacatcacac acttgtctaa ggctcttcgt cctcttcctg
      661 agaaattcca tggtttgaca gacgttgaaa caatttaccg taaacgttac cttgacttga
      721 tttctaaccg tgaaagcttt gaacgctttg tcactcgttc aaaaatcatc tctgaaatcc
      781 gtcgttacct tgaccaaaaa ggattccttg aagtggaaac acctgttctt cataatgaag
      841 ccggtggtgc tgctgcccgt ccatttatca cccaccacaa tgcccaaaac attgacatgg
      901 tgcttcgtat cgcgactgag cttcacttaa aacgccttat cgtgggtggt atggaacgtg
      961 tctatgaaat tggccgtatc ttccgtaacg aaggaatgga cgctactcat aaccctgagt
     1021 ttacttctat cgaagtttac caagcttatg cagacttcca agacatcatg gacttgacgg
     1081 aaggcattat ccaacacgct gctaaatcag ttaagggcga tggcccagtc aactaccaag
     1141 gtactgaaat caagattaac gaaccattta agcgtgttca tatggtggat gctatcagag
     1201 aaattactgg tgtcgatttc tggcaagaca tgactttgga agaagctaaa gctatcgctg
     1261 ctgagaagaa agttccagtt gagaaacact acactgaggt tggtcacatc atcaatgcct
     1321 tctttgaaga gtttgttgaa gaaactttaa tccaaccaac ctttgtctat ggacatccag
     1381 tagctgtatc tccactcgct aagaaaaatc ctgaagacca acgctttact gaccgtttcg
     1441 agctctttat catgactaag gagtacggta atgcctttac tgagttgaac gacccaatcg
     1501 accaacttag ccgttttgaa gcccaagcta aagctaaaga acttggtgat gatgaagcga
     1561 caggcatcga ctatgactac atcgaggctc ttgaatacgg tatgccacca acaggtggtt
     1621 tgggaatcgg tatcgaccgt ctctgcatgc tcctcactga tacaacaact atccgtgatg
     1681 tattgctctt cccaacaatg aaataaattc ttaccctctg gctcttacca ggggattttt
     1741 tgattcaaaa agagactgaa tttaaggaga aaatgaagtg tagtatattg aagttgaaat
     1801 agtacacttt gatttctaag acattgttag aaattggttt aaattcccta atcaatttgt
     1861 gcatgtttta tttcatttta cgatagtacg ctgaaactgt tcaaaaagta ctagaaattg
     1921 acttggattc cccaattgat ttgttcagat tcactataaa taaaaaatta ataagtggga
     1981 taggaagtta gcgtcaacta ggatagtatc ttgcttaaac agtatatatg ggactgatat
     2041 aagtccatag gtcctattag aggatgttct ggtgtcttat tcacttgttt ttttatagta
     2101 ttagtagata gaatccgcaa ataaaaaagt agttcaaatg cctggcagca aaaaatctca
     2161 acgattcact taatatagac taaagtttag agtttaagga aagtagggct agtatattgt
     2221 atgaaaaaat aagatggttt ttaagcaaaa ctcttgaaaa tgattgaaaa aagagttatt
     2281 atagttgtgt agtaaaaagc aaacgcttac ttaatcaagg agggcatttt atgtcataca
     2341 aaacaagcaa tgcagaaggt catgtagact tcatcaatac ctatgatttg gagccaatgg
     2401 cgcaacaagt tattcctaaa gcagcatttg gctatatcgc tagtggggcg gaagatactt
     2461 tcactttaag agagaatatc cgcgccttta accacaaact catcgttcct catacacttt
     2521 gcgatgttga aaatccaagt acagagattg aatttgcagg tgaaaaacta tcttcaccaa
     2581 tcattatggc gcctgttgcg gctcataaat tggcaaatga acagggggaa gtggcgactg
     2641 cgcgtggtgt gcatgagttt ggttctcttt atacaaccag ttcttactct actgttgacc
     2701 ttccagagat ttctgaagcc cttcaaggga cacctcattg gtttcaattt tactttagta
     2761 aggatgacgg tatcaaccgc cacatcatgg accgtgtgaa ggctgaaggt tataaagcga
     2821 ttgtcttgac ggcagatgct actgtagggg ggaatcgtga agtggataag cgtaatggtt
     2881 ttgtcttccc agttggcatg ccgattgttg aagaatacct gccagaaggt gctggtaaat
     2941 caatggactt tgtttacaaa tcagctaaac aacgcttgtc tccacgcgat gtagaattta
     3001 tcgctgaata ctctggtctt cctgtgtatg tcaagggacc acaatgccgt gaggacgttg
     3061 aacgttcgct tgctgcagga gcttctggta tctgggtaac caaccacggt ggtcgtcaaa
     3121 tcgacggtgg accagctgcc tttgactcgc ttcaagaagt ggcagaagca gttgatagac
     3181 gtgtgccgat tgtctttgac tctggtgttc gtcgtggtca acacgtcttt aaagccttgg
     3241 cttcgggagc agacttggta gctattggtc gccctgttat ttatggcttg gctctcggtg
     3301 gtagtgtcgg tgtgcgtcaa gtctttgaac acttgaatgc ggaattgaag acagttatgc
     3361 aattgtctgg agctcagacc attgaagatg tcaaacactt taagctccgt cacaatccat
     3421 acaacccaac cttcccagtt gaccctcgtg acttaaaatt gtattgataa aacagattgc
     3481 ctccactgaa tgtggaggtt tttcttcgtg tattggaaga ataaattgct atcgaaaact
     3541 atagtaaaat gaaataagaa taggacaaat caatcaggac agtcaaatcg atttctaaca
     3601 atgttttaga agtagaggtg tactattcta gtttcaatct actatataaa gatatttttc
     3661 ggtcaaatat cttgctaggg ctttcatttt ttgctatact ggttcagtaa ttaaataata
     3721 gagacatttg gggtgcttta ggctgagata atacccattg aacctgatac agttaagact
     3781 ggcgaaggga aatgtgaaca gttttttcgt atggtgaaat gaacggtcta atcttgtaag
     3841 tcaactctaa ttcttgattg taattggagt tttttgttta tataaactgg ataggcttgt
     3901 ttagttagct ctctgtaaat gctctcgatg tgctttaaaa ggatcaagtg gaattacgat
     3961 tttgcttgat atttcttgct gttttattaa ttactaacaa gtaaagagag gagaagtaaa
     4021 tatggaaaca caagactatg catttcagcc aggtttgact gttggagaat tattaaaaag
     4081 cagtcagaag gattggcagg ctgcaatcaa tcatcgtttt gttaaggaac tttttgcggg
     4141 gacaattgag aataaggtct taaaggacta tctgattcaa gattatcact tctttgatgc
     4201 cttcttatcc atgctgggtg cctgcgtagc tcacgcagat aaacttgaat ccaagcttcg
     4261 ttttgccaag caactaggct ttcttgaagc agatgaagat ggttatttcc aaaaggcttt
     4321 taaagagtta aaagtagcag agaatgacta cctagaagtg actttgcacc ctgtaacaaa
     4381 agcctttcag gatctaatgt attcggcggt ggcttcatca gactatgccc atcttttggt
     4441 tatgctggtc attgcagaag gtctctattt agactggggt tctaaagatt tggctctacc
     4501 tgaagtctat attcattcgg aatggatcaa tctccacaga ggtcctttct ttgcagagtg
     4561 ggttcaattt ctggttgacg aactcaatcg tgtcggtaaa aatcgagaag atttgacaga
     4621 acttcagcaa cgctggaatc aagcagtcgc tttagaatta gctttttttg atattggtta
     4681 cgatgtctag agaaggctca tgatatttac aaatttgatg aggtaagact cttcgaaaat
     4741 ctcttcaaac cacgtcagtt ctatccacaa cctcaaaaca gtgttttgag caacctgcgg
     4801 ttagcctcct agtttgctct ttgattttca ttgagtataa atcattcaac gtaaatgaaa
     4861 aaaatttctt aacgaaagat agagataaat cgaaatcagt agatcgtata aagtgtaaag
     4921 gaaggatttc aatatgacaa gtttaaaatt attaaaagaa aaagcaccat tggtcatttg
     4981 tataaccaat gatgtagtaa aaaatttcac agcaaatgga ttagtagcac tgagcgtctc
     5041 accagccatg agtgagtttc cagcagattt agaggatttg ttaaagtatg ctggtggttt
     5101 attagtaaac ataggaacat tgacagatga aaattggaaa ttataccaag ctgctctgaa
     5161 aattgcggag aaatataatg tcccagcagt tttagatcct gtagcctgtg gagcaggaga
     5221 atatagaaaa aaagtagcag atgatctaat caacaattat aaactagcag cgattagagg
     5281 aaatgctggc gagattgcct ctttagtagg aatagatgtg gcatctaaag gagtagatag
     5341 tgcgggagta gataatattg acgagattgc tctagcagca aatgagaagt tcaatattcc
     5401 aatagtagta acaggtgaag tggatgctat tgcggtaaat ggagaagtgg taacgattca
     5461 taatggtagt gctatgatgc cgaaagtcat tgggacagga tgcttattag gagctgtagt
     5521 agcaagcttt atcggactag aaaaaggtca agaattgaaa tcattagaaa cagcaatgtt
     5581 ggtttacaat atcgctggag aaatagcaga aaaacgtccc aatggacatc ttcctggaac
     5641 atttaaagtt gaatttataa atgccttata cgagattaca gatgaagatg tcaagaaatt
     5701 caaaagagtg aagtaagatg tttcataaag aattactaaa actatatttt atttgtggaa
     5761 cgactacttg ccaaggaaaa gatctatata cagtcgttga ggaagcctta aaaggtggta
     5821 taaccttatt tcaatttcga gaaaaaggtg agggtgcttt agaaggctta gaaaaacttg
     5881 agctagctat ccaaattaaa gaactttgta aaaaatacaa tgttccattt atcgttaatg
     5941 acgatataga tttagcaatg gaaattgacg ccgatggcgt acatgtaggt caagatgata
     6001 ttggtgttga tgaaattaga aaattgatgc cagataaaat aattggtctt tctataagaa
     6061 acgaagaaga atttcaacaa tcaaaagttg aatatgtaga ttatgtaggt gttgggcctg
     6121 tatttggtac ccagtcaaag gatgatgctg gtggtactat aggttatgaa ggtcttgaat
     6181 tgatgagaaa actattgcca caaatgcctt tagttgcaat tggtgggata cagacgaaac
     6241 atattaaaga cattataaag accaatatgg atggcgtttc aatcatttcg gcaatatcgt
     6301 atgcaaaaaa tatagaaaaa actgttcggg aaatgagtga acaatagata tctatccttg
     6361 gattctaagt aagtaggatt ttcctttttt aaaaagctat gtccagattc agcttgaatg
     6421 gctaattcat caaacaggtc atttgttttt tgtaaaagaa agatctgctg tctttgtgag
     6481 tgcaaggctg tatttccagt tcaatttctt gaactagtat aaaatgtgtg ttataataat
     6541 cacataatta aataataaag acatttgggg tgctttaggc tgagatgata cccattgaac
     6601 ctgatacagt taagactggc gaagggaaat gtgaaatgtt tttttcgtat gtcgaaaaga
     6661 actgtctaat cttgtaagct gaactctaat tcgtatctgt aattagagtt ttttctttta
     6721 cgaaactgga tgaagatgat atagtagatt gaaataagat gcgaacaaat caattagaaa
     6781 attcaaatta atttctagaa atattttagt gttcttgtgt actgttctaa attcagtttg
     6841 ctatacaaag tatttaggtc ggtcttcttg agtgccccac ttttctttaa aaaaaggagt
     6901 tttttatgtt gaaaaaatgg cagttaaaag atgttatctt gcttgctttc ttgtctatct
     6961 tttttggtgg ggttttcgtt ggttcaggat atgtgtataa tattctcagt ctactcttaa
     7021 cacctcttgg tttgcaggcc tttgctaatg aaatcctctt cggtctctgg tgtatggctg
     7081 cgcccattgc tgccatcttt gttccgagag tcggaagtgc aacgattgga gaagtgctag
     7141 ctgcgcttgc tgaagtcctt tatggtagcc aatttggtct aggagctctt ttgtctggct
     7201 tggttcaagg tttgggaagt gaatttggtt ttatcgtaac taagaatcgc tatgaaagtt
     7261 ggctctctct aactgctaat agtattggga ttacgcttgt tagctttgtc tatgaataca
     7321 ttaagttagg ttactacgcc ttttcccttc cgtttgtcct ttccttgctt gtggtacgtt
     7381 ttatttctgt ttatttcttc tgtaccatct tggttcgtgc cattgtcaaa ctctatcatc
     7441 agtttgcaac tggaggaaaa gcatagatgg gtctggaact acgagcgatt cagtccccaa
     7501 tcttctctga gccgtttgat tttacttttc atgcgcaagc ctttaccttg ttagttggga
     7561 gcagtggttc aggaaaatcc agcctctttc aaatgattgc ccaagtcagt tctcttccct
     7621 atagtggtca agtcctgata gatgggagcg aggtcagtca gctttctatc atcgcacgtg
     7681 tccagaaggt tggcattctc ttgcaaaatc ccaatcatca atttaccatg gagaacttgt
     7741 ttgaggagtt gattttcacc ttggagaata tcggctatca ccttcaggaa attgattcta
     7801 aaatagcaga ggttgtccag caatgtcgtt gcgaggcaat cttacaccgt cccattcatc
     7861 acctatcagg tggggaaaag caaaaagcag cgctggctgt cctctttgcc atgaatccta
     7921 gggtctatct cttggatgag cccttcgctt ccattgaccg caagagcaga atcgagatat
     7981 tggagattct aaaagagttg gctcttgatg ggaagacagt tattttgtgc gaccatgatt
     8041 tatctgacta taaagcctat atcgaccata tggttgagct aagagacgga aaactaaggg
     8101 aagtgtttca aatcccttcc tatgagatga cacaggttgc ttcaaaggaa gttgcttcta
     8161 gcccggaact attccatatg gatagaacga cttgtgagtt tggaaatcgc tccctctttt
     8221 cgattgctga tttcacattc tatcaaggga tttcctgtat cctgggtgac aatggtgtcg
     8281 ggaaatcaac cctctttcgg tctattcttc aatttcaaaa gtataagggg cgcattgcat
     8341 ggaaggggac agtcctgaaa aagaaaaaga gtttgtaccg tgatctgacg ggtgttgttc
     8401 aggaagctga gaagcagttt atccgagtca gtctgcgaga ggagcttcaa ttagatggac
     8461 ctgattctga aagaaatcag cggatttttc aagctttacg atattttgat ttggagcagg
     8521 cagtcgataa gagtccctat caattaagtg gtggtcagca aaaaattctt cagctcctga
     8581 ccatcttgac cagtaaggct tccgtgatct tgctagatga accttttgca ggtttggatg
     8641 atagagcctg ccattatttt tgcaagtgga ttgtggagga gaggaatcaa ggaagaagtt
     8701 ttctgctcat tagtcatcgt ttagaccctt tgatttctgt ggttgattat tggattgaga
     8761 tgactagtca gggtcttcgg catgtgaaag aagtgaccat taccaaacca cttacatctc
     8821 agagtagcaa tacccaaggg gaggtgagat agtatggtca aagtagcaac ccagacaccg
     8881 attatcagtc tcttcttgct gattttatcc ttggaaacat ctttcattcc ttcgattgct
     8941 ctgaatcttt cggtagtcgc attttgtatt ctctttatgc tctattaccg tcgatttaaa
     9001 atgttagctt ggatgatcat acttgccatt ttaccatctt ttgccaacta ctgggcagtt
     9061 cagttacacg gagatgcttc acaggcagtc atgcttggaa cgagggcctt tgtgacagtt
     9121 tgtatcggcc ttgtctttgt ttcctctatt tcactaaaag agcttctctt gtacttggct
     9181 caaaaggggc tatcacgctc ttggtcctat gccttgattg tggtattcaa ttcttttcct
     9241 ctcattcagc aagaaatcaa gtccctcaaa gaagcttgcc tattacgtgg tcaaaaacta
     9301 catttttggt cgcccttgat ttacagtaag gttctgatga cagtctttag gtggcgccat
     9361 ctttacctga gagctctatc tgctcacgga tatgacgaac atgcacagtt gaagaatagc
     9421 tatcggactt tttatattcc taaaaaaaca aaattaatct acctgctttt ctttttattg
     9481 cttcaaacca gtctattttt ataaaggagt tattatggaa tttacagata ttgcgatgga
     9541 attatccaag aaagcttggc aggcttcctt tcatcatccc tttattttac aattacaaga
     9601 ggggaattta gaacctgcca ttttccgcta ttacctgatt caggatgcct actatctgaa
     9661 ggctttctca gaaatctatc atcttttggc tgataagact tcaaaccaag agatgaaaag
     9721 actcttgaaa caaaatgctc agggtttagt ggagggtgag ttatttattc gccaacaatt
     9781 tttcaaggaa ttggaaatca acgaccagga aatggagcaa catccaatcg ctccaacctg
     9841 ttatcattac atttctcata tttataggca atttgcagaa ccgaacttag ccatagcttt
     9901 tgcaagcttg cttccttgtc cttggttata ccatgatata ggcaaatcac ttaatcttaa
     9961 accatcacca aatcctctct atcaacaatg gattgaaact tatattacgg atgagttaga
    10021 gcaacagatc agagaggagg gagcactggt caatcagctt tatcgagaaa gtgatgagac
    10081 agataagcaa aaaatgctag atgccttcca catcagtgtt catatggaag ccaagttttg
    10141 ggagatggct taccaacacc agacatggaa gagcgattta cagtctttag aaaaaggaga
    10201 agaatagaaa catgagaaag caccaactac aagttcacaa attgaccatt ttatctatga
    10261 tgattgccct tgatgtagtc cttacaccta tctttcggat tgagggaatg gcaccgatgt
    10321 ccagtgtagt caatattcta gcgggaatca tgatgggacc tgtttatgcc ttggctatgg
    10381 ctacagtgac agcctttatc cgtatgacga ctcaagggat tccgccttta gctctcacag
    10441 gagcgacttt tggagccctt ctagcaggtc tcttttataa gtacggtcga aaattttact
    10501 tttctgcctt gggagaaatt gtgggaacag gtattattgg ttctattgtt tcctatcctg
    10561 ttatggtgct ctttacagga tcggctgcta agcttagttg gtttatctac actcctcgat
    10621 ttttcggagc aaccttgatt ggtacagcga tttcctttat tgcatttaga tttttaatca
    10681 agcaggaatt ctttaaaaaa gtgcaaggat atttctttgc tgaaaggata gaatgatgca
    10741 ggcattgaca aatccttttc ctataggctc tagttccctc attcactgta tgaccaatga
    10801 gatttcttgt gagatgctgg caaatgggat tttggctctg ggatgcaaac ctgtcatggc
    10861 agatgatccc cgtgaagttc ttgattttac taagcaaagt caggctctct tcatcaattt
    10921 ggggcatttg tcagctgaga aggaaaaagc aatccgcatg gcagcttcgt atgcaaacca
    10981 atcttctctc ccgatggtag tagatgcggt tggcgtaacg acttcatcca ttcgtaagag
    11041 cttagttaaa gaccttttag actatagacc tacggtcctt aaaggaaaca tgtcagaaat
    11101 tcgaagtctt gttggattaa agcaccacgg cgttggggtc gatgcgagtg ctaaagatca
    11161 agaaacggag gatttgcttc aagtcttgaa agactggtgt cagacctctc ctggtatgtc
    11221 tttcttagtt actggcccca aggaccttat tgtttcggag aatcaagttg ctgtactgga
    11281 gaatggctgt actgaattag actggataac agggacagga gacttggttg gagccttaac
    11341 agccgttttt ctcagccaag gaaagactgg ttttgaagct tcttgcttag cagtctctta
    11401 tctcaatatc gctgctgaga aaatagttgt tcaaggaatg ggattggaag aatttcgtta
    11461 ccaagtactc aatcagcttt cgctcctaag aagagatgaa aattggctag ataccatcaa
    11521 aggagaggtt tatgaataga gaagcactta gactatatct ggtaaccaat cgctatcaag
    11581 attccgtgga aagctttctt gcaaaagttg agacggcctg ccgttcaggg gttaccatag
    11641 tccaattgcg agaaaaaaat ctcacaacca atcaatatta tcaactggca aaacaagtca
    11701 aggaaataac agatgcctat caggtcccct tgataatcga tgatcggttg gatgtttgtc
    11761 ttgcggttga tgctgctggt ctgcatattg gagatgacga actcccagtt tcggttgccc
    11821 gacaagtctt gggtcctgaa aaaatcctcg gtgtcaccgc taaaacggtt aaaagagctc
    11881 tggaagcgga gaaatcaggt gcagattact tggggacagg agccattttt ccgacaacca
    11941 ccaaggaaaa tgcacccatc accctgattt caaccttgaa aacaatttgt caaacggttg
    12001 ccattccagt agttgctatt ggcggcttga cttcggagaa tattgatcag cttatgggca
    12061 ctggcatagc tggtgtagct gttgtacgtg atttgatgca agcagaagat attgaggcaa
    12121 aaacgcaagc ctttttaaca aagttgcatg acattctttc ctaattaata ctcaatgaaa
    12181 atcaaagagt aaactagaaa gctagtcgca ggttgctcaa agtactgcct tgaggtttta
    12241 gataagactg atgaagtcag ctcaaaacag tgttttgagg ttgcagatgg aagctgacgt
    12301 agtttgaaga gattttcgaa gagtataaaa actctctaat tcccttaaag tgggaactag
    12361 agagtttttt tcttaatctt taaaagttgt atggttgact ggaccagaac catgaccgag
    12421 ttgaggggca tcttgaatag cttttgtgat aaaggccttg gccttatcaa ctgcctggta
    12481 aagactcttg cccttggcta gttcagcagt aatcactgca gcaaaggtac atccagtacc
    12541 atgggtgtga caggtttgaa ttcgtgggct ttcccagaca aattgttcat tcttggtaaa
    12601 gaggaaatct ttagcaccac ctttgagatg tccgcctttg ataaccacag actgaggacc
    12661 aaattctttt aaaatcaggc gaccagcacg ctgcatgtct tcggggtcat ggattgaaaa
    12721 accaacaatc tcttctgctt caggaagatt tggcgtaata atagttgcta gaggtagtaa
    12781 gtttgttttg agatagtctc tagcacttga gtcaatcaag gcatctccac ttgtagcaac
    12841 cataacagga tcaaggacat agggacaatc cagtttttta agatagggtt ggatgatttc
    12901 catgatttca gtagtagcca acattccagt ttttacagcc tgaggtggaa tatcagaaaa
    12961 gacactctcc aattgggctt tcaacatttg aggagaaacg tgctcgatta gctgaacacc
    13021 tctggtattt tgagcgacaa gactggttac aacagccatt ccatagacat ctctcgcttg
    13081 gaatgacttt aaatctgcca taatgccagc accaccacta gggtcagtcc ctgcaatggt
    13141 caaagcaacg ggtaaataag tcatctaaaa cctcccaacc aactgaagtt tgtattctta
    13201 agaacaagct agtctgtttt agaaaggcaa tagaagactg ctagtcccca ttatcatttc
    13261 cacttccatc agctagcatt acctagattg agtcagaggg atctaacagt cgttaatctc
    13321 agctttacgc acccctagtg gttgttttct tttttcttta gtatagcata tttttattgt
    13381 ttatatagta atatttgact gcaaatcgtt tttcaaatga ttaaaattct atttttcgaa
    13441 gaaaatatta tttctataat tgacaaatgt agattttggg agtatactgt tgagtgtaat
    13501 tgacaaatgt agattttgga ggtatggtaa tgcagatttc agatgcagaa tggcaggtca
    13561 tgaagattat ttggatgcag ggggagcaga ccagtacaga tttgattagg gttttggcag
    13621 agcggtttga ctggtccaag tccacggttc agacactttt ggctcgtcta gttgagaaag
    13681 agtgtttgac tcggaaaaaa gaaggcaagt cctttgttta ttcagcgctt ttaactctag
    13741 accaaagtcg ggatttactt gtccaagata tcaaagacaa ggtttgttcc cgtaggatta
    13801 ggaatttgtt ggctgacttg attgtagaat gtgaatttac tcagactgac ttggaagact
    13861 tggaagctgt gatttcagag aagaaatcaa gtgctgtaac agaagtaaga tgtaattgta
    13921 tgtaaaggag acgtcatgtt aaatagtatt gtaaccatta tttgtattgc ccttatcgcg
    13981 tttatcttgt tttggttttt caaaaagcct gaaaaatctg gacaaaaagc ccagcaaaaa
    14041 aacggatacc aagagattcg agtggaagtc atgggaggct atactcctga gttgattgtc
    14101 ctcaagaaat cagtgccagc ccgcattgtc tttgaccgca aggatccttc accatgtctg
    14161 gatcaaattg tttttccaga ttttggtgta catgcgaacc tgccaatggg ggaagagtat
    14221 gtagtggaaa tcacgcctga acaggctgga gagtttagct ttgcttgtgg tatgaacatg
    14281 atgcacggca agatgattgt agagtaggtg gagactatga cagaaattgt gaaagcaagc
    14341 ttagaaaatg gcattcaaaa aatccgtatc caagctgaaa aaggctatca tccagcccat
    14401 atccagcttc aaaagggaat tccagctgag attacctttc atcgtgctac tccttcaaac
    14461 tgttataagg aaattctgtt tgaagaagaa ggtatcttgg aaccaatcgg cgtagatgag
    14521 gagaaagtca ttcgttttac acctcaagaa ttagggcgac atgaattttc ttgtggcatg
    14581 aagatgcaaa agggaagcta tacagtcgtt gagaagactc gaaaatctct atctctcctg
    14641 caacgttttt ggattactag tatctgtact gtgcctcttg tgattctcat gattgggatg
    14701 ttggcaggta gcattagtca tcaagtcatg cattggggaa cctttctagc aacaacgcct
    14761 attatgttag ttgcaggtaa gccatatatc cagagtgctt gggccagttt taaaaagcac
    14821 aatgccaaca tggatacctt ggttgcgctg ggaactctag tggcttattt ctatagccta
    14881 gttgctctct ttgctggtct ccctgtttac ttcgaaagtg ctggatttat cctctttttc
    14941 gttcttttgg gagcagtttt tgaggaaaaa atgagaaaaa atacgtccca agctgtggag
    15001 aaattactgg acttgcaagc taaaaccgca gaagtcttga gtgatgatag ttatgtccaa
    15061 gttcctttgg aacaagtcaa ggtaggcgac ctgattcgag tgcgtcccgg tgaaaagatt
    15121 gctgttgatg gtgtcgtagt agaaggtgtc tctagtattg acgaatccat ggtgacaggt
    15181 gagagtctgc ctgtggacaa gacagttgga gatactgtca ttggctcaac catcaatcat
    15241 agtggaacgc ttgtctttag agcagaaaaa gttggctcag agactgtttt ggctcagatt
    15301 gtggattttg tgaagaaagc tcagacaagt cgtgcgccga ttcaggactt gacggataag
    15361 atttcaggga tttttgtccc agtagttgtc attttaggaa tcatgacctt ttgggtttgg
    15421 ttcgtcttgc tcagggatag tgtggttgtg cttggagcta gctttgtgtc ctctcttctc
    15481 tacggagtgg cggttttgat tatcgcctgt ccttgtgcct tgggacttgc aacaccgaca
    15541 gcccttatgg tggggacagg acgtagtgcc aagatggggg ttctcctcaa aaatggaact
    15601 gtcttacagg aaatccagaa agttcaaacc cttgtctttg ataagaccgg gactttgacg
    15661 gaagggaaac ctgtggtaac agatgtcatc ggcgacgaag tagaagtgtt tggattggca
    15721 gcctccttgg aagatgcttc tcaacaccca ctggctgagg ctatcgttaa gcgagcgagt
    15781 gaagctggac ttgagtttca aactgttgaa aattttcagg ccttgcacgg gaaaggtgtt
    15841 tcagggcgaa tcaatggaaa acaagtttta cttggaaatg ctaaaatgct ggatggcatg
    15901 gatatttcta atacttatca agataaacta gaagaactag aaaaagaagc taagacagtt
    15961 gtgttcttag ctgttgacaa tgaaatcaaa ggcttgcttg ctttgcaaga tattcctaag
    16021 aaaaatgcta agctagccat cagtcagcta aaaaaacgtg gtctcgggac agtcatgctg
    16081 acaggagaca atgctggtgt ggcgcgtgct attgcagatc aaatcggaat tgaagaggtc
    16141 attgcaggcg tcttgccaga agaaaaagcc catgaaatcc ataaactgca acagtcaggt
    16201 aaagtagcct ttgttggtga tgggatcaat gacgctcctg cccttagtgt agcagatgtg
    16261 gggattgcta tgggagctgg aacagatatc gccatcgagt cagcagattt ggtgttgaca
    16321 accaataatc ttttaggagt ggtgcgtgcc ttcgacatga gtaagaaaac ctttcatcgt
    16381 attctgctca atcttttctg ggcttttatc tacaatgttg tcggaattcc gattgcagca
    16441 ggagtctttt caggtgttgg actggctctc aacccagaat tggcaggtct agccatggcc
    16501 tttagttctg tatctgttct gaccagttcc cttctgttaa attttagtaa aatagactaa
    16561 aagtaatgac tagatttttt tgttataaaa cagaaatgac gacactttca aaactgtatt
    16621 agaatagaga atagagagtt ttgagcagat ttttagaaaa gtcagcataa atatgataca
    16681 gtggaatagt aaaaatttgg agaacgtttc caattctatg taatcgtatt ctccaagtct
    16741 aaaaaaattg aaggagagtt atcattatga ctcaagggaa aattactgca tctgcagcaa
    16801 tgcttaacgt attgaaaaca tggggcgtag atacaatcta cggtatccca tcaggaacac
    16861 tcagctcatt gatggacgct ttggctgaag acaaagatat ccgcttctta caagttcgcc
    16921 acgaagagac aggtgctctt gcagcggtta tgcaagctaa attcggcggc tcaatcgggg
    16981 ttgcagttgg ttcaggtggt ccaggtgcga ctcacttgat taacggtgtt tacgatgcag
    17041 ctatggataa cactccattc ctagcaatcc ttggatcacg tccagttaac gaattgaaca
    17101 tggatgcttt ccaagagctt aaccaaaacc caatgtacaa cggtatcgct gtttacaaca
    17161 aacgtgtagc ttacgctgag caattgccaa aagtaattga cgaagcctgc cgtgctgcag
    17221 tttctaaaaa aggtccagct gttgttgaaa ttccagtaaa cttcggtttc caagaaatcg
    17281 acgaaaactc atactacggt tcaggttcat acgaacgctc attcatcgct cctgctttga
    17341 acgaagttga aatcgacaaa gctgttgaaa tcttgaacaa tgctgaacgc ccagttatct
    17401 atgctggatt tggtggtgtt aaagctggtg aagtgattac tgaattgtca cgtaaaatca
    17461 aagcaccaat catcacaact ggtaaaaact ttgaagcttt cgaatggaac tatgaaggtt
    17521 tgacaggttc tgcttaccgt gttggttgga aaccagccaa cgaagtggtc tttgaagcag
    17581 acacagttct tttccttggt tcaaacttcc cattcgctga agtttacgaa gcattcaaga
    17641 acactgaaaa attcatccaa gtcgatatcg acccttacaa acttggtaaa cgtcatgctc
    17701 ttgacgcttc aatccttggt gatgctggtc aagcagctaa agctatcctt gacaaagtaa
    17761 acccagttga atcaactcca tggtggcgtg caaacgttaa gaacaaccaa aactggcgtg
    17821 attacatgaa caaactcgaa ggtaaaactg agggtgaatt gcaattgtat caagtttaca
    17881 atgcaatcaa caaacatgct gatcaagacg ctatctactc aatcgacgta ggtaacacta
    17941 ctcaaacatc tactcgtcac cttcacatga cacctaagaa catgtggcgt acatctccac
    18001 tctttgcgac aatgggtatt gcccttcctg gtggtatcgc tgctaagaaa gacaatccag
    18061 atcgccaagt atggaacatc atgggtgacg gagcattcaa catgtgctac ccagacgtta
    18121 tcacaaacgt tcaatacgac cttccagtta tcaaccttgt cttctcaaat gctgagtacg
    18181 gcttcatcaa gaacaaatac gaagatacaa acaaacactt gtttggtgta gacttcacaa
    18241 acgctgacta cgctaaaatt gcggaagctc aaggagctgt tggattcaca gttgaccgta
    18301 tcgaagacat cgatgcagtt gttgcagaag ctgttaaatt gaacaaagaa ggtaaaactg
    18361 ttgtcatcga tgctcgcatc actcaacacc gtccacttcc agtagaagta cttgaattgg
    18421 atccaaaact tcactcagaa gaagctatca aagccttcaa ggaaaaatac gaagcagaag
    18481 aactcgtacc attccgtctc ttcttggaag aagaaggatt gcaatcacgc gcaattaaat
    18541 aattcctctc gccgaaaatc aaatatgaaa cttgtagact ttattctttg attttcatag
    18601 agcagaactt taaaagatcg gagcaatccg gtctttttat ggaggagagt aaatgaattt
    18661 aaatcaatta gatattatcg tttcaaatgt tccccaagtc tgtgctgact tggagcatat
    18721 tttggataaa aaggcagatt atgctgatga tggttttgct cagtttacga ttggtagtca
    18781 ctgccttatg ttgtcacaaa atcatttggt tcctttggaa aactttcagt caggaatcat
    18841 tattcatatc gaggttgagg atgtagacca gaactacaaa cggttgaacg agcttggtat
    18901 aaaggtttta cacggaccaa ctgtaaccga ttggggaaca gagtccttat tagttcaagg
    18961 acctgctggt ctagtgcttg atttttatcg tatgaaatag gtcgcgtagt catttgacgt
    19021 taaccttagc tatttttaaa atagaaattg agaatatgaa ctattgaaag atcggagcaa
    19081 tccggtcttt ttatataaag aaattgcata taatactcat atgctttcaa aaagcattct
    19141 agtccatctc cgattaacga tggactttat cacctccttc tccagtcctt gtatgacatc
    19201 ttgaagttga ttcatgacat cttccaaagt tcgaaaggcc ttattcttaa atccacgttt
    19261 acgaatctct ttccacactt gttcaatggg ttcatctctg gtgtgtatgg aggaataaag
    19321 gtaaaaccaa tattagtcgg aatctttaag gtacttgatt tatgccatat agcattgtcc
    19381 ataacgagta aaagataatc atctggataa gcttgtgaaa gctcttctaa aaaggcgttc
    19441 atccactcag tattacatcc accagctatt aagaaaaatg attcgcctgt atggggcatc
    19501 aacagctcca taacaatagc gaaattctcg tatatagtga ctatggacat gtggacctac
    19561 tcctattgga gaccaacaag atcccagttt actgattcta ccgaaatcag cctcatcttg
    19621 gtacatcaag cgaaccttat gaaaaggtct actggtttta aagcgctttc ttgtcttctt
    19681 gaattgagat tttattttta gacgcgacaa tggtttgagc gtctgctttc ttaggatgtt
    19741 ctggacgtgg cataatattt cgccaaccat ggtgcttcaa cagttgatag aaggcatcac
    19801 gtgtgtagga acgatataag cctgaaataa ggtattgtaa caaattctcc tgcctctgta
    19861 gccttcaaat ggcgggcaag aaaggctttc tcttcctaaa ctgtcatata tgcatggtta
    19921 cgaccaccac gtgtttcttg aaggagagag tcgagtccga actcctcata ttttttacat
    19981 ttcgccaaat cgttgtttga ttacagtcta aaagctctat aatctcttta taagatttgc
    20041 ccatcagacg aaatatagta gattgaaact agaatagtac acctctactt ctaaaacatt
    20101 tttagaaatc gatttgactg tcctgatcga tttgccctgt tcttgtttcg ttttactata
    20161 gaacgatttg aaggcgttta tgatatttag ctgtacgaga gtcttttaaa agtgttttga
    20221 tggcttggat ttcttcttta gttgatttca tatcactatt atataatgct ttttgatttt
    20281 agtttagtat tatcgtagaa aatggactcg gtgctatgga tacaccggat gagaatggtt
    20341 atgtagcaga taactatcgg attacttact tagaggccca catcaaggcc atgcgagatg
    20401 ccatttacaa agacggggtt gacttgtttg gttatacgac ttggggctgt accgatccgg
    20461 tttcagctgg cacaggggaa atgaataagc gctatggctt tatctatgta gatcgagata
    20521 atgtaggaaa cggagctctc aaacgtagca agaagaagtc cttctattgg tacaaggatg
    20581 tcattgatag caatggtgca agcatcgggt agagcacatt tgtttactat ttttataaaa
    20641 tcttctccct gctttataag atgtaaaaaa gagttcaatt cgaactcttt ttttgctata
    20701 atgaggggag aaaaatcaga caggagatcg acatgtcaga accattattt ttacaatcag
    20761 ttatgcaaga aaaaatctgg ggtggagcca agctacgtga tgagtttggc tacgacatcc
    20821 caagtgaaaa aatcggagaa tattgggcca tctcagccca tccaaatgga gtctctaaag
    20881 ttgccaatgg tcgttacgag ggaacagatc ttgctacttt gtatgcggaa caccgtgaat
    20941 tatttggcaa tcgtccagaa cctgtatttc cacttttgac caagatcctc gatgccaacg
    21001 actggctcag tgtccaagtt cacccagacg atgcttatgg gctcgagcat gaaggcgaac
    21061 tcggaaaaac agaatgctgg tacattatcg cagcggatga aggttcagag attatctacg
    21121 gtcacaatgc caagtcaaaa gaagaactcc gccagcaaat cgaggataag aactgggatg
    21181 cgctgttgac aaaagtgcca gttaaagcag gagatttctt ctatgtacca agcggtacca
    21241 tgcacgctat cggggcgggt atcttgattc ttgaaaccca gcagtctagc gataccactt
    21301 accgtgtcta tgactttgac cgtaaggatg acaagggcaa tttacgtgaa cttcaccttg
    21361 aaaaatctat cgatgtcttg aacattggtg aacccgcaaa tagccgtcca gtgacaatca
    21421 aagcagatga tctatgttcc actctccttg tatccaatga tttcttcgca gtttacaaat
    21481 gggaaattac tggaaaagtt aactttgaaa agacagctga ctacagcttg ttgagtgtct
    21541 tggctggtca aggtcaacta actgttgacg ggaaaaacta tccaatccaa aaagggagac
    21601 actttatcct accaagtgat gttgaagctt ggactctgga agggcaagat ttagaattaa
    21661 ttgttagtca tccataaaaa agaaagggcc tgagttcatt actcaagtcc ttttgattac
    21721 ataaattggg cgatgaagac cacgatgatg attggaatga cggaacgaag aaacgaagaa
    21781 ggaagagcca gacttggaac agtccttgtt tccatgctct ttcatcgaga tggagttcct
    21841 ccattgcaag agccttttta aagatatagc ctgtaaaaag tgaaaggtag agagctccaa
    21901 atggcatgag gagattggaa accaagaagt ccatagcgtc aaagaaggtc ttaccaaaaa
    21961 tgtgaacatc cgccatgaca ccgtaagata gggctgaagg aatgccaaag acaaaggtca
    22021 aaattcctaa aataacactc catttggcac gtttgctgtt atcctggttg gtgatattgc
    22081 ccacattgat ctccagcatc acgacagaag aagtgacagt cgcaaagagg aagaggacgt
    22141 agaaaatggt tccaaaagac atcttgtcaa agagttgagg caagacgata aagagcaagc
    22201 tcggtccccc ttcagactgg atattgaagg gggatcgagc ttggaaaatg gctagacctg
    22261 ccatgatgga tatcgagata ttcatggcta cgatggagat tcctgactgg actagattgg
    22321 ttttcttgtc caagtaagaa gcataggtca acatgactgt aacccctagt gagagggcaa
    22381 agaaagattg tcccagagca tagaggagac cagcgctagt cagttttgaa aagtctggtt
    22441 tgaggaagta aagaacccct tccatggcat ttggcaaact gagagagcga cagatgataa
    22501 caacaaagat gataaagagc aggggcatca tgactttcga agctctttca atcccttttt
    22561 gaaccccacg tgatacaata aagatattta ataagataaa ggctgcttga gctactaggg
    22621 caatggctgg atttgaaatg attgaagtaa ataactgagc ataatcaccc gttccaccaa
    22681 gttggaacaa tttcccaaac tcaataccta gatagactag aatccatcct ccgataacac
    22741 tgtaaaaaga taagaggata aagagggcaa aggcgccaat ccaaccgata aagttgtact
    22801 tgttattctt gcccagtttt ccaaaggttt tgatagcgga aacgccagca ctacggccaa
    22861 gggcaaactc agccagcagg agagggaaac cgattaaaat agtggaaatg agaaagatta
    22921 gtaaaaagcc tccaccgcca ttagcagcag tcatgtaggg aaacttccaa acggaatcaa
    22981 gcccgatggc cgagccagca gatgctagaa taaaaccaag tttcgacccc cattgtgatt
    23041 tttctgacat agttaaactc tgatctcctt tttcaaaata agaaaaagct acttgagttg
    23101 tcaaatagcc ttctgtttga ttgatagact tgactatcct attatgtttt ctaaggtctg
    23161 tcaagaaaac cattttcaag ttttcacacc tttctcaaaa acgcttgact ctgacctaag
    23221 gggaggggtt atactatcat tgtaaggagg aaatcatgta ccatataaaa gaagctgcgc
    23281 agctttcagg tgtctctgtc aagaccctgc atcactatga caagatagga ctcttggtcc
    23341 ccttaaagtc ggaaaagggc tatcgaacct atagtcaaga ggatttggaa cgccttcagg
    23401 tcattcttta ctacaaatat ctaggctttt ctttagagaa aatagcagag ctgttaaagg
    23461 aagaaaggac agatttattg ccccatttga ctaggcagtt ggactatcta actcgcgaaa
    23521 ggcaacatct ggataccttg atttccacct tgcaaaaaac tattcaagaa caaaaaggag
    23581 aaagaaaaat gaccattgag gaaaaattca cgggatttag ctatcaagac aatcaaaaat
    23641 accaccaaga agcggtagag aaatatggtc aagaagtcat gggacaagcg ctcgaacgcc
    23701 aaaaaggtca cgaagacgag gctacggccg cctttaacca agtctttcaa actttggcac
    23761 aaaatcttca agttggttta cctgcaacag caaccgaaaa ccaagagcaa gcagccaagc
    23821 tcttgcaagc cattcgcact tatggatttg actgctctat tgaggtattc ggtcatatcg
    23881 gtaaaggtta cgtctacaac ccagagttta aggaaaacat tgacaagttt ggttctggaa
    23941 cagcccagta cacgtcagat gccattgcag cttacgttca gacaaatgca gaaaaaatag
    24001 gctaggaatt tcctagccta ttttttactt caaatcataa agccagtcgt caccgttttt
    24061 gtagtaaaag aattcactga gatcttcttc tagaaacaca cgaagcatat cagacatatc
    24121 atcggttgca agttttagat gagaaagatt ttcaaagtcc tcccaccaaa ctttcccttc
    24181 gtctgaagac tggagttcac cagtaaagtg ttctgtcttg taaaaaagga cgacataacg
    24241 ataatccttg tcgtcatacc agtttttgat accacagagt tggggtttgg aaatgatcag
    24301 accagtttct tctttcactt cacgaatgac agcatcgaca aaggattcgc cacgttcaac
    24361 atgaccacca ggaaaagtaa tgccaggcca gtcgggacta actcggtctt ggaccaggac
    24421 cttatctccg tttttaatca tacacatgtt aacaaattcg actgcttctc ttctgttcat
    24481 tcttcacaac ctttaatctt taatcataat gcagacttcc cgccacccag ccggtacaga
    24541 gggcagaagt gatgttaaag ccacccgtgt gggcattgat atccataact tcgcctgcaa
    24601 agtggaggcc aggtaccagc ttactttcaa gggttttagg attgatttcc ttgagactga
    24661 ctccaccctt ggtaacaaag gactttgcaa gggacatttt tccagttaca ggaattttaa
    24721 gttctttaat ggactggaca agctgttctc gttccttttc agtcagctgt ttgacttttt
    24781 caggatatct ttgtacaaaa aattcggcca agcgttctgg taacaaggtt tttaaagcgt
    24841 ttttcaagga tttttcccga tttttttcta gaaatgtaac caagttcttc tcagaaagtt
    24901 gaggcaaaac atcgagtgag agaacctccc caccgtttac aaagctagac atgcgtaggg
    24961 cagcaggacc tgacaaacca aagtgggtaa agagtaaatc atgagtgatg acatgcttac
    25021 cataacttag ggtcacatcg tccagagaaa tcccttgtaa ggctttatgt ggaaaatctg
    25081 ttaataaagg actttcagca gcctcaagat cggtgatggt atgcttaaaa tggcgagcaa
    25141 tctcgtgacc aaaaccagtc gaaccagtcg aaggataaga cttaccacct gttgtgacaa
    25201 tgagtttctc acaagtgaag gtttgatccg ctgacttaag gacaaactgg ttatctactt
    25261 ttttaacaga aacgatttct atttgagtag caacttgacc acctagttcg gtgattttct
    25321 tttccaaagc ttcgataata gtccgagact tgtcactggc tggaaagacg cgtccgtggt
    25381 cttcgacctt aagtttaaca ccattttctg taaaaaagtt gatgatgtca tgattatcga
    25441 actgggagaa aacactgtaa agaaagcgtc cgtttccagg aattccagct agcaggttgt
    25501 ctaagctacc attgttggtc acattgcaac gtcccccacc agtcccagct aatttttttc
    25561 caagtttccg atttttttcg atgaggaggg ttttctgtcc ataaaagcta ctggaaatcg
    25621 tagccatcat accagcaggt cccccaccga tgacaatagt atcaaaatgt ttcatagctc
    25681 tattgtacca caaaaaaaca agagatgatg gtcacctctt gtcaagaatg caattaatca
    25741 atttcatagc ccatcagcaa accgccctct tctgcataga aactgcagag accagaggtt
    25801 ggtagaattt taatatccgc ttgtgggaag gtttcacgga ttcgctctga gagctgttga
    25861 caacattttt cgttattgcg ttgggccatg acaatacggc caccagcata tccagctttt
    25921 actaactcat cataggcagc ttgaactgat ttctttgatc cccttgcttt ttgtagcaat
    25981 tcgagagtcc cagtttcact agcttttccg accatacgaa tgttgagaag gccaacgacc
    26041 gtaccgataa gcttgctcaa acggccgttc ttcaccaagt tatcgacttt ggctaggaca
    26101 aagagcaact tagttttttc ttgataggcg gtgatagctt caaccacttc ttcaaaagac
    26161 aagccctggt caatcaagtc attcaatttt tctacgagta ggtcaacttc accaccagca
    26221 gataaactat caatcacatg aatcttagtg tcaggatggt cttccagata aatattcttt
    26281 gctagttgag cactattgtg actgccagaa agggtacctg tgatggttac taggaaaatg
    26341 tttttggcac cttcaaatgc tcgcaaatag tcatctgggc ttggacaagc cgattttgaa
    26401 gcttctgcag ttgcatacat ggtttccatc atttggtcaa tatcgagact ggcgtcatca
    26461 acaaagacct gatcagctac ttgaatggtt aaggggacac ttacaaaggt tgtgttaata
    26521 gctggtgttg gcagttgacg ataatcacaa ccagagtcag caataatttt ccaagtcata
    26581 gaaattctcc atctttgtca gttatacatt gacaaaggtt ctgtcttttt ttacaattat
    26641 atcatgaaaa cccttgaaac aaaagcatca tccgtctgtt gtgacaagta gaaagaaaat
    26701 gttatgtctg aacgtagaat ctctgaaaag tctcttgaaa atctcagaaa atcaaaccaa
    26761 gaatccaatt tattaaccag agaagccatt gaaacagccc tcttgcaact cttggaaaaa
    26821 aaggagctga ccaagattag tatttctgaa ttggtcaaac gtgcaggtgt ttcgcgtgcg
    26881 gccttttatc gcaattatga ctccaaagag gaaattttag agagcgtctt taaacgaact
    26941 gtccacaata ttatggaaca gctgcatcat tacgatttaa agacagacct ttatttggtt
    27001 tgggttcacc ttttccggga ggccagaaag gaagctagag tgattcaatt ggccttggat
    27061 taccatctgg aaaaaatctt tgtccaagcc atgcaggaat ttctagaaaa ataccatggg
    27121 aaatcaaaag gtgtcagctc ttatcttcat tccttctgga gctcagccat cgtctctgtc
    27181 cttctaaaat ggatcaagga tggcatgaag gtaccagctg aaaagattgc agatttaggt
    27241 ttaccatttt ttaaaaaata gagaaaaagg agaaaagaga tgactgaaaa aagactggcc
    27301 tgggatgagt attttgcagc ccaagcccta ctaattgcga atcgttccac ttgtaaacgt
    27361 gctaaagtgg gcgcgattct ggtaaaagat aataaggtta tttccactgg ttacaatggt
    27421 tcggtgtcag ggactgagca ttgtattgat cacgaatgtt tgatcattga aggccactgt
    27481 gttcgcaccc ttcacgctga ggtcaatgct atccttcaag gtgctgagcg tggtgttccc
    27541 aaaggcttta cagcctatgt aacccatttt ccttgtctca actgtacaaa acaattgctt
    27601 caggtcggct gcaagcgcgt ggtttatatc aaccagtacc gaatggacga ctacgcccaa
    27661 tacctttatc aagaaaaagg gacagaattg acccatttac cacttgagac agtacagaca
    27721 gctcttaaag aggctgatct aatgtaaaaa ttatcaaaaa taaatggctt agaaagattt
    27781 ttaaaccgtt ttttggtata ataagaagaa taaattgaaa gaaggaattc caaaaatggg
    27841 aaaaattgaa gttattaatc acccactgat tcaacacaaa ttgtcaatct tgcgtcgtac
    27901 agatacttct acaaaagctt ttcgtgagct agtagatgag attgcaatgt tgatggggta
    27961 tgaagtactt cgtgatcttc cactagaaga tgtggaaatc gaaacaccaa ttacaaaaac
    28021 agttcaaaaa caattggcag gtaagaaatt ggccatcgtc ccaatcttgc gtgcaggtat
    28081 cgggatggtt gatggtctct tgagcttggt tccagctgct aaagttggcc acatcggtat
    28141 gtaccgtgat gaagaaacac ttcaaccagt tgaatacttg gtgaaattgc ctgaggacat
    28201 tgaccaacgt caaatttttg tagtagaccc aatgttggca acaggtggct cagcaatctt
    28261 ggctgttgat tctcttaaaa aacgtggcgc atcaaatatc aaatttgtct gccttgtatc
    28321 tgctccagag ggtgtaaaag cccttcaaga agctcatcca gatgtagaaa tctttacagc
    28381 agccttggat gaacgtttga acgaacacgg ttatatcgtt ccaggtcttg gagatgctgg
    28441 agaccgcttg ttcggtacaa aataagatcg aaaagaagaa tgacttggaa aagtatttct
    28501 agtcacgaaa ggaggttggg tttttgtttc tgtctaatga aagcagagca aaaatttgac
    28561 cttttttgac caagatatta taatagtctt atcttcagtc atttgaccaa caaaattaaa
    28621 actcaaaagg agaaatgaat gattcctgta gttattgaac aaacaagccg tggagaacgt
    28681 tcttacgata tttactcacg tcttctcaaa gaccgcatca ttatgctgac aggtccggtt
    28741 gaagacaata tggctaactc tgttattgcc caattgcttt tcttggatgc ccaagatagt
    28801 acgaaagata tttaccttta tgtcaataca ccaggtggtt ctgtttcagc tggtttggca
    28861 atcgtagata ccatgaactt tatcaaggca gatgtccaaa ccattgttat gggaatggct
    28921 gcatctatgg ggactgtcat cgcatcaagt ggggcaaaag gcaaacgttt catgcttcca
    28981 aatgctgaat acatgattca ccaaccaatg ggcggtacag gtggtggtac ccaacaaact
    29041 gatatggcta tcgctgcaga acacttgctc aaaactcgta ataccttgga aaaaatcttg
    29101 gctgaaaatt caggtcagtc aatggaaaaa gtccatgcag atgcagaacg tgataactgg
    29161 atgagcgccc aggaaacact tgaatatggc tttattgatg aaattatggc caacaattca
    29221 ttgaactaat gatgatagaa ggcaaactcg actgggtttg ctttttttgg tataataggg
    29281 agagatttct tagaaagagg atttatcatg tttgaaaaag tcaatcgctc tggcttgatt
    29341 atctatcttt actataatcg tgatgccaaa aaactgcagg attatggaga tattacctat
    29401 cattccaaga aacatcgtta cttacaactc tatgttccaa ctcaagaagt ggagcaattg
    29461 gtcggacgct tgagcaagga aaaatttatt aaaaaagtta gagtttgtca tatccaagag
    29521 ttggaaacac cctttgtggg caatctttat cgataggaaa acgttatcat cgaaaaagtt
    29581 caaggaaaac attgacaatt ttctgataat tcggtatatt cttaacagac tatttaagaa
    29641 ataaggagac aaaaaagatg aagaaaaaat ttgccctatc gtttgtggcg cttgcaagtg
    29701 tagcacttct tgcagcctgt ggagaagtga agtctggagc agtcaacact gctggtaact
    29761 cagtagagga aaagacaatt aaaatcgggt ttaactttga agaatcaggt tctttagctg
    29821 catacggaac agctgaacaa aaaggtgccc aattggctgt tgatgaaatc aatgccgcag
    29881 gtggtatcga tggaaaacaa atcgaagtag tcgataaaga taataagtct gaaacagctg
    29941 aggctgcttc agttacaact aaccttgtaa cccaatctaa agtatcagca gtcgtaggac
    30001 ctgcgacatc tggtgcgact gcagctgcgg tagcgaacgc tacaaaagca ggtgttccct
    30061 tgatctcacc aagtgcgact caagatggat tgactaaagg tcaagattac ctctttattg
    30121 gaactttcca agatagcttc caaggaaaaa ttatctcaaa ctatgtttct gaaaaattaa
    30181 atgctaagaa agttgttctt tacactgaca atgccagtga ctatgctaaa gggattgcca
    30241 aatctttccg cgagtcatac aagggtgaaa tcgttgcaga tgaaactttc gtagcaggtg
    30301 acacagactt ccaagcagcc cttacaaaaa tgaaagggaa agactttgat gctatcgttg
    30361 ttcctggtta ctataatgag gctggtaaga ttgtaaacca agcgcgtggc atgggaattg
    30421 acaaaccaat cgttggtggt gatggattca acggtgagga gtttgtacaa caagcaactg
    30481 ctgaaaaagc atcaaacatc tactttatct caggcttctc aactactgta gaagtttcag
    30541 ctaaagctaa agccttcctt gacgcttacc gtgctaagta caatgaagag ccttcaacat
    30601 ttgcagcctt ggcttatgat tcagttcacc ttgtagcaaa cgcagcaaaa ggtgctaaaa
    30661 attcaggtga aatcaagaat aaccttgcta aaacaaaaga ttttgaaggt gtaactggtc
    30721 aaacaagctt cgatgcagac cacaacacag tcaaaactgc ttacatgatg accatgaaca
    30781 atggtaaagt tgaagcagca gaagttgtaa aaccataata gaaaaatgtt gaaataggga
    30841 atgagccttt gactcactcc ctgtttcgat atttaatact cttcgaaaat ctcttcaaac
    30901 tgcgtcaacg tcgccttgga ttatatatgt gactgacttc gtcagtctta tctacaacct
    30961 caaagcagtg ctttgagcaa cctgcggcta gtttcctagt ttgctctttg attttcattg
    31021 agtataagaa cctatcaaaa agtgagggaa acccctcgga attataaata gaaagagtga
    31081 atcttatgct ccaacaactc gtaaatggtt tgattctagg tagtgtttac gcgctgttag
    31141 ccctaggata taccatggtt tacggaatta tcaagctcat caacttcgcc catggtgata
    31201 tttatatgat gggagccttt atcggttatt tcttgatcaa ttctttccaa atgaatttct
    31261 ttgtagcgct tattgtagct atgctagcga cagctattct tggtgtcgtg attgagtttc
    31321 ttgcttaccg acctttgcgc cactctactc gtattgctgt tttgattacg gctattgggg
    31381 tttctttcct attggagtat ggaatggtct atctggttgg tgccaatacc cgtgccttcc
    31441 ctcaagcgat tcaaacagtt cgatatgatt tgggaccaat tagcttaaca aatgtgcagt
    31501 taatgatttt ggctatttcc ttgattttga tgattttgtt acaagtcatt gtccaaaaga
    31561 ctaagatggg gaaagccatg cgtgcagtat cagtagatag cgacgcggcg caattgatgg
    31621 ggatcaatgt aaaccgtacg attagcttta ccttcgcttt gggttctgct cttgcgggtg
    31681 cggctggtgt tctgattgct ctttattata actctcttga gcctttgatg ggggttactc
    31741 caggtcttaa atctttcgtt gccgcagtac ttggtggtat cggaattatt cctggtgcgg
    31801 ctcttggtgg ctttgtgatt ggtctattgg aaacctttgc gactgccttt gggatgtcag
    31861 atttccgtga tgccattgtt tatggaatct tgttgttgat cttgattgtc cgcccagctg
    31921 gtatccttgg taagaatgtg aaagagaagg tgtaaacgat gaaggaaaat ttaaaagtta
    31981 atattctatg gttactcctt ttgttagctg gctatagctt gattagtgta ctggtttcag
    32041 tcggagtact taatctattc tatgtacaga ttttacagca aattggaatt aatattattt
    32101 tggctgttgg tctcaactta atcgttggtt tttcaggaca attttcactt ggtcatgctg
    32161 gtttcatggc gattggtgcc tatgcagcag ctattattgg ttctaaatca ccaacctacg
    32221 gtgccttctt tggagctatg cttgtagggg ctttgctttc aggagcagtt gccttacttg
    32281 tcggcattcc aaccttgcgc ttgaaggggg actatcttgc ggtagcaact ctaggtgttt
    32341 ctgaaattat ccgtatcttt atcatcaatg gtggaagcct tacaaatggt gcggcaggta
    32401 ttttagggat tcctaacttt acaacttggc aaatggttta cttctttgtc gtgattacaa
    32461 ccattgcaac cttgaacttc ttgcgtagcc caattggtcg ttcaaccctc tctgttcgtg
    32521 aagatgaaat cgctgctgag tcagttgggg ttaatacgac taaaattaaa atcatcgctt
    32581 ttgtctttgg tgccattact gcaagtattg ctgggtcact tcaggcagga tttatcgggt
    32641 ctgttgtacc gaaagattac accttcatca actcaatcaa cgttttgatt attgttgtat
    32701 ttggtggact cggttccatt acaggtgcga ttgtttcggc tattgttctg ggaattttga
    32761 atatgcttct ccaagatgtt gctagtgtgc gtatgattat ttacgctttg gccttggtat
    32821 tggtaatgat tttcagacca ggtggactcc ttggaacgtg ggaactgagc ctatcacgtt
    32881 tctttaaaaa atctaagaag gaggaacaaa actaatggca ttacttgaag taaaacagtt
    32941 aaccaaacat tttggtggtc taacagctgt tggagatgtg actcttgaat tgaacgaagg
    33001 ggaactggtt ggattaatcg gtccaaacgg agctgggaaa accacccttt tcaacctttt
    33061 gaccggtgtt tatgaaccaa gcgagggaac agtaacccta gatggtcacc ttttgaatgg
    33121 gaaatcacct tataagattg cctctttggg acttggacgt actttccaaa atatccgtct
    33181 ctttaaagat ttaacagttt tagacaatgt tttgattgct tttggaaacc atcacaaaca
    33241 gcatgttttt actagtttct tacgcttacc agctttttac aagagtgaaa aagaattaaa
    33301 ggctaaagct ttggaattgt tgaaaatctt tgatttagat ggtgatgcag agactcttgc
    33361 taaaaatctt tcctacggac aacaacgtcg tttggaaatt gttcgtgccc ttgctacgga
    33421 acctaaaatt ctcttcttag atgaaccagc agcaggtatg aacccacagg aaacagccga
    33481 attgactgag ttaattcgtc ggatcaaaga tgaatttaag attacaatca tgttgattga
    33541 acacgatatg aatctggtca tggaagtaac agaacgtatc tacgtacttg aatatggccg
    33601 tttaattgct caaggaactc cagacgaaat taagaccaat aaacgcgtta tcgaagctta
    33661 tctaggaggt gaagcctaat gtctatgtta aaagttgaaa atctttctgt gcattacggt
    33721 atgatccaag cagtccgtga tgtaagcttt gaagttaatg aaggagaagt tgtttccctt
    33781 atcggtgcca acggtgcagg taagacaact attcttcgca ccttgtcagg tttggttcga
    33841 ccaagttcag gaaagattga atttttaggt caagaaatcc aaaaaatgcc agctcagaaa
    33901 atcgtggcag gtggcctttc acaagttcca gaaggacgcc acgtctttcc tggcttgact
    33961 gttatggaaa atcttgaaat gggagctttc ttaaagaaaa atcgtgaaga aaatcaagct
    34021 aacttgaaga aggttttctc acgctttcct cgtcttgaag aacggaagaa ccaagatgca
    34081 gctactcttt caggagggga acaacaaatg cttgccatgg gacgcgctct tatgtcaaca
    34141 ccaaaacttc ttcttttaga tgaaccatca atgggacttg ccccaatctt catccaagag
    34201 atttttgata tcattcaaga tattcagaag caaggaacaa ccgtcctctt gattgaacaa
    34261 aatgccaata aagcacttgc aatctctgac cgaggatatg tattggaaac aggaaaaatc
    34321 gtcctatcag gaacaggaaa agaactcgct tcatcagaag aagtcagaaa agcatatcta
    34381 ggtggctaaa acaatccagt ggattgtttt agtcggcaga tgaagattac gaagtaatca
    34441 tcaatatagt ccgggggccc tttttagtcg gtggatgaag attgcgaagc aatcatcaaa
    34501 tccagaggat tgttttagcc ggtagattga gattgcaaac aaatctgcat ctacattgaa
    34561 agctgaattt ctaataattg aaaaaatcga atgaaacgta tcttaccttc attcagggag
    34621 ctcgatttta gagctctttt tgctagctta ttcatacttt tttgaatttc gaaaaagaaa
    34681 tgtaagcgtt tgatagattt acaaaaagat tgtataatgg ggataagaat agaaaaggag
    34741 aagtctcatg gcagttaaag attttatgac ccgcaaggta gtttatatta gtccagatac
    34801 aacagtatct catgcagcag atttgatgag agagcaagaa ttgcaccgct tgcctgttat
    34861 cgaaaatgat caattggttg gtttggtgac tgagggaacc attgcacaag caagtccatc
    34921 taaagcaaca agtctttcta tctatgagat gaattatctt ctgaataaga caaaagtaaa
    34981 agatgtcatg attcgcgatg ttgtcactgt ctcaggctat gctagtctag aagatgcaac
    35041 ttatctgatg ttgaaaaata agattggtat tctccctgtc gtagataacc atcaagtata
    35101 cggagttatt actgaccgtg acgttttcca agcctttctt gaaattgcag gttatggcga
    35161 agaagggatt cgtgtacgct ttgttacaga agatgaagtt ggtgttcttg gaaaaattgt
    35221 ttctttgatt gtagaagaaa atttgaatat ctcccataca gtcaatattc cgcgtaagga
    35281 tggtaaggtc attatcgaag tgcaaatcga tggatcaatt gatttaccag ccttgaaaga
    35341 aaaatttgaa gcaaatggta ttcaagtgga agaaatcgct cgcacttcag caaaagtctt
    35401 gtaagaaggg aagcccaaag gcttcttttt tcatgaaaag gggattagag aaaaagatgg
    35461 aaagaaatga taaaatatgc tataatgaaa taatgtaaaa aaggagtatt tatggacatt
    35521 tcagtaattc gtcagaaaat tgacgcaaat cgtgaaaaat tagcttcttt cagggggtct
    35581 ctttgacctc gaagggctag aggaagagat tgccatcttg gaaaacaaga tgacagaacc
    35641 tgatttttgg aacgataata ttgcggccca aaaaacgtcg caagaattaa atgaattaaa
    35701 aaacacttac aataccttcc ataagatgga agagttgcag gatgaagtcg aaattttatt
    35761 ggattttttg gctgaagacg agtcagtgca tgatgaactg gtagcgcagt tagccgaact
    35821 tgataagata atgaccagct acgagatgac tctactcttg tcagaacctt atgaccacaa
    35881 caatgccatc ttggaaatcc atccaggttc tggtggtact gaggcgcagg actggggtga
    35941 tatgttgctt cgtatgtata ctcgttatgg taatgctaaa ggctttaaag tggaagtgtt
    36001 ggattaccaa gcaggtgatg aggctggtat taagtcggta actttatcat ttgaagggcc
    36061 taatgcctat ggtctcctca agtcagaaat gggtgttcac cgcttagtgc gaatctcacc
    36121 atttgactct gccaaacgtc gccatacctc tttcacatct gtagaagtga tgccagaatt
    36181 ggatgatact attgaagtgg aaatccgtga agatgatatc aagatggata ccttccgttc
    36241 aggtggtgcc ggtggacaaa acgtcaataa ggtttcaaca ggtgtacgtt taacccacat
    36301 tccaactgga attgttgtcc aatcaacagt ggatcgtacc cagtatggaa atagagatcg
    36361 tgccatgaag atgttgcagg ctaagctcta tcaaatggag caagataaga aggctgcgga
    36421 ggtagattct ctcaaaggtg agaaaaagga gatcacttgg ggaagccaaa tccgttctta
    36481 tgtcttcacg ccttatacta tggtaaaaga tcaccgaact agctttgagg ttgctcaggt
    36541 agataaggtt atggatgggg acctagatgg ttttatcgat gcttatctca agtggcgaat
    36601 tagctaagat agaaaggaac tcacatgtca attattgaaa tgagagatgt cgttaaaaaa
    36661 tacgacaacg gaacaactgc tctacgcggt gtttcggtta gcgttcaacc gggggaattt
    36721 gcttacatcg taggaccttc aggagcaggg aagtcaactt ttattcgttc tctgtatcgt
    36781 gaagtaaaaa tcgataaagg aagcctatca gttgctggtt ttaatctggt taagatcaaa
    36841 aagaaagatg tcccgcttct acgtcgtagt gttggggttg tcttccagga ttataaactg
    36901 ttaccaaaga aaactgtcta tgaaaatatt gcttacgcta tggaagtaat cggggaaaat
    36961 cgccgtaata tcaaaagacg agtgatggaa gttttggact tggttggatt gaagcataag
    37021 gttcgttctt ttccaaatga actctcaggt ggggagcaac agcgaattgc gattgcgcgt
    37081 gcaattgtaa ataatcccaa agtattgata gctgatgagc caacaggaaa tctggatccg
    37141 gataattcat gggaaattat gaatctcttg gaacggatta acctacaagg aacaactatt
    37201 ttgatggcga ctcataatag ccagattgta aataccttgc gccaccgtgt cattgccatt
    37261 gaaaatggcc gtgtcgttcg tgacgaatca aaaggagagt atggatacga tgattagtag
    37321 attttttcgc catttatttg aagccttaaa aagtttgaaa cgaaatggtt ggatgacagt
    37381 agctgctgtc agttcagtca tgattacttt gaccttggtg gcaatatttg catctgttat
    37441 tttcaataca gcgaaactag ctacagatat tgaaaataat gtccgtgtag tagtttatat
    37501 ccgaaaggat gtggaagata atagtcagac aattgaaaaa gaaggtcaaa ctgttacaaa
    37561 taatgactac cacaaggtat atgattcttt gaagaacatg tctacggtta aaagtgttac
    37621 cttttcaagt aaagaagaac aatatgaaaa attaaccgag ataatgggag ataactggaa
    37681 aatctttgaa ggagatgcca atcctctcta tgatgcctat attgtagagg caaacactcc
    37741 aaatgatgta aaaactatag ccgaagatgc taaaaaaatt gaaggtgtct ctgaggttca
    37801 agatggcggt gccaatacag aaagactctt caagttagct tcatttatcc gtgtttgggg
    37861 actagggatt gctgctttgt taatttttat cgcagttttt ttgatttcaa ataccattcg
    37921 tattaccatt atttcccgca gtcgcgaaat tcaaatcatg cgcttggtcg gagctaaaaa
    37981 cagttatatc cgtggaccgt tcttgttaga aggagccttt atcggtttat tgggagctat
    38041 cgcaccatct gttttggtct ttattgttta tcaaattgtt tatcaatctg tcaacaaatc
    38101 gttggtaggg caaaatctat ccatgattag tccagattta tttagtccgt tgatgattgc
    38161 cctactattt gtgattgggg ttttcattgg ttcattggga tcaggaatat ccatgcgccg
    38221 attcttgaag atttaggtaa aatagctgct tttatgagga gattgtaaaa tctccttttt
    38281 tgctacaaga gtttttgaaa agagatgcgc agaagaaaag gctctttgtc aactgtagtg
    38341 gttgaagaaa agctaagctt gagaaaggac aaatttcgtc ctttcttttt tgatgttcag
    38401 agcgataaaa atccgttttt tgaagttttc aaagtttcga aaaccaaagg cattgcg
//
LOCUS       DAVMAH010000015        37872 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVMAH010000015 DAVMAH010000000
VERSION     DAVMAH010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37872
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.015"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(114..596)
                     /gene="greA"
                     /locus_tag="VYO94_000713"
     CDS             complement(114..596)
                     /gene="greA"
                     /locus_tag="VYO94_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV1759379.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(667..2322)
                     /gene="mltG"
                     /locus_tag="VYO94_000714"
     CDS             complement(667..2322)
                     /gene="mltG"
                     /locus_tag="VYO94_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV1759380.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2403..2897)
                     /locus_tag="VYO94_000715"
     CDS             complement(2403..2897)
                     /locus_tag="VYO94_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1759381.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2894..3358)
                     /locus_tag="VYO94_000716"
     CDS             complement(2894..3358)
                     /locus_tag="VYO94_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1759382.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3368..4702)
                     /locus_tag="VYO94_000717"
     CDS             complement(3368..4702)
                     /locus_tag="VYO94_000717"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV1759383.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     DQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEVEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4713..5330)
                     /locus_tag="VYO94_000718"
     CDS             complement(4713..5330)
                     /locus_tag="VYO94_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1759384.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTAPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5378..8476)
                     /locus_tag="VYO94_000719"
     CDS             complement(5378..8476)
                     /locus_tag="VYO94_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1759385.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYIIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFAVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPSKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8569..9735)
                     /locus_tag="VYO94_000720"
     CDS             complement(8569..9735)
                     /locus_tag="VYO94_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1759386.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            complement(9743..10837)
                     /locus_tag="VYO94_000721"
     CDS             complement(9743..10837)
                     /locus_tag="VYO94_000721"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1759387.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQAIEG"
     gene            complement(10994..12676)
                     /locus_tag="VYO94_000722"
                     /pseudo
     CDS             complement(10994..12676)
                     /locus_tag="VYO94_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768988.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(12848..14809)
                     /locus_tag="VYO94_000723"
     CDS             complement(12848..14809)
                     /locus_tag="VYO94_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1759388.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRATTNDIVTNLVDGLMENDQYGNYVPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGI
                     KALDDQTVQYTLARPEPYWNSKTTSTILFPVNADFLKSKGDDFGKVDPANILYSGPFL
                     MKAFVSKSVIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQDALVRNFTDGAYSYARLYP
                     NSSSFEGIKEKYKDDIIYSMQDATSYYWNFNLDRQAYKFTSKTTDIEKKSTQEAVLNK
                     NFRQAINFAYDRTSYGAQTQGEDGATKILRNLVVPPTFVSIKGKDFGEVVASKMVNNY
                     GKEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDATVDQASKKGIQE
                     VSSMKQSIEAALGTENVVIDIQQLSTEDYDNSSYLAQTAIQKDYDLYNGGWSPDYLDP
                     STYLDIFSVKNGGVLQNLGLDPGEANDKAKAVGLDTYTQMLEEANKEQDPAKRYEKYA
                     DIQAWLIDSSLAIPNVSLGGTPSLRKTVPFSAPYSLAGNKGVESYKYLKVQDKIVTTD
                     EYAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(15013..16635)
                     /locus_tag="VYO94_000724"
     CDS             complement(15013..16635)
                     /locus_tag="VYO94_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1759389.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            16741..18186
                     /locus_tag="VYO94_000725"
     CDS             16741..18186
                     /locus_tag="VYO94_000725"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV1759390.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYIAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISLDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FRFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMGIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(18232..18414)
                     /locus_tag="VYO94_000726"
     CDS             complement(18232..18414)
                     /locus_tag="VYO94_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1759391.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGLKNVFTK"
     gene            complement(18515..19033)
                     /locus_tag="VYO94_000727"
     CDS             complement(18515..19033)
                     /locus_tag="VYO94_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV1759392.1"
                     /translation="MIRYLDQYEDVILCENKRYYLNFPTLESLDSLELDQEIFVREAS
                     PVYQALLEQSFETELRNQINAAILVEKTDFARIKMTLSNYFYKVKQQYPLTEKQQELY
                     DILGDVNPEYALKYMTAFLLKFLKKDQLMQKCRDIFVDSLVVLGYIVQNEDGKYELAI
                     DFDKERLTFYLA"
     gene            complement(19070..19582)
                     /locus_tag="VYO94_000728"
     CDS             complement(19070..19582)
                     /locus_tag="VYO94_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV1759393.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLRDSDF"
     gene            complement(19668..20603)
                     /locus_tag="VYO94_000729"
     CDS             complement(19668..20603)
                     /locus_tag="VYO94_000729"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV1759394.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(20674..20937)
                     /locus_tag="VYO94_000730"
     CDS             complement(20674..20937)
                     /locus_tag="VYO94_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV1759395.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGRGAKYKGFA
                     SKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(20927..21676)
                     /locus_tag="VYO94_000731"
     CDS             complement(20927..21676)
                     /locus_tag="VYO94_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV1759396.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(21730..22089)
                     /locus_tag="VYO94_000732"
     CDS             complement(21730..22089)
                     /locus_tag="VYO94_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV1759397.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(22091..23491)
                     /locus_tag="VYO94_000733"
     CDS             complement(22091..23491)
                     /locus_tag="VYO94_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV1759398.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFAALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(23786..24025)
                     /locus_tag="VYO94_000734"
     CDS             complement(23786..24025)
                     /locus_tag="VYO94_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV1759399.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(24057..24527)
                     /gene="ssbA"
                     /locus_tag="VYO94_000735"
     CDS             complement(24057..24527)
                     /gene="ssbA"
                     /locus_tag="VYO94_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV1759400.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(24539..24829)
                     /locus_tag="VYO94_000736"
     CDS             complement(24539..24829)
                     /locus_tag="VYO94_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV1759401.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(24982..26328)
                     /gene="asnS"
                     /locus_tag="VYO94_000737"
     CDS             complement(24982..26328)
                     /gene="asnS"
                     /locus_tag="VYO94_000737"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV1759402.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(26344..26709)
                     /locus_tag="VYO94_000738"
     CDS             complement(26344..26709)
                     /locus_tag="VYO94_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1759403.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSERLIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(26702..27889)
                     /locus_tag="VYO94_000739"
     CDS             complement(26702..27889)
                     /locus_tag="VYO94_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1759404.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAESRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKEAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(27886..28374)
                     /locus_tag="VYO94_000740"
     CDS             complement(27886..28374)
                     /locus_tag="VYO94_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV1759405.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            28695..29243
                     /locus_tag="VYO94_000741"
     CDS             28695..29243
                     /locus_tag="VYO94_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1759406.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGASALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            complement(29521..30249)
                     /gene="yaaA"
                     /locus_tag="VYO94_000742"
     CDS             complement(29521..30249)
                     /gene="yaaA"
                     /locus_tag="VYO94_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV1759407.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(30328..30492)
                     /locus_tag="VYO94_000743"
     CDS             complement(30328..30492)
                     /locus_tag="VYO94_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV1759408.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(30659..32254)
                     /locus_tag="VYO94_000744"
     CDS             complement(30659..32254)
                     /locus_tag="VYO94_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759409.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRVYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            complement(32266..32676)
                     /locus_tag="VYO94_000745"
     CDS             complement(32266..32676)
                     /locus_tag="VYO94_000745"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1759410.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(32792..33583)
                     /gene="yghU"
                     /locus_tag="VYO94_000746"
     CDS             complement(32792..33583)
                     /gene="yghU"
                     /locus_tag="VYO94_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV1759411.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(33596..36292)
                     /locus_tag="VYO94_000747"
     CDS             complement(33596..36292)
                     /locus_tag="VYO94_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV1759412.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAMDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LLEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFLMIIIVEIVKFIQRKLGFDKNAI"
     gene            36596..37780
                     /gene="mntE"
                     /locus_tag="VYO94_000748"
     CDS             36596..37780
                     /gene="mntE"
                     /locus_tag="VYO94_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV1759413.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
BASE COUNT        10923 a         8522 c         7186 g        11241 t
ORIGIN      
        1 aaccatacat acggcaaggc gacgctgacg tggtttgaag agattttcga agaatagcaa
       61 aatggaaaaa ggagtgagtg aagcacatcg cctccccact cctttttctg tttttaggct
      121 gttttttcaa ccttcaagat ttttacatca tagctaccaa caggcgtttc aatggttgct
      181 gtatcacctg ttttcttgcc aatcaaggcc tgcccaattg ggctttcatt tgaaacctta
      241 cctgcaaagg catccgcacc agctgaacct acgataatat aaacttcttc ttcgtcctca
      301 ccaatttctt ggatggtgac tgttttacca atcgctactt cgtcctgggc aactgcgtcg
      361 ctattgacga tttcagcata gcggattttt gtttctaagc tagagatttg tccttcgaca
      421 aaggcttgtt catccttagc tgcttcgtac tcactgtttt ctgaaaggtc accgtatgaa
      481 cgggcaatct taatgcgttc taccacttct ggtcgacgaa ccaatttcaa ttcttctaat
      541 tctttttcaa gtttctcctt ttcctcaagg gtcataggat atgttttttc tgccattttt
      601 ctcaactttc ttctgataat attttctaaa gaaaattatg tgaagtatca cataatttta
      661 gtttgtttag tttaatttgc tgttgacatg ttcagcgaca ttgcggtcgt ggtcttcttg
      721 attgttagca tagtagacct tgccttctgt gacatctgct acaaagtaga ggttatcgct
      781 cttagtttga ttgatgcttg actcaatcgc atccagactt ggactatcga ctggaccagg
      841 catgagacct acatttttat aaacattata aggtgaatca atgttggtat caatcgcaac
      901 atcctcagct agactgatat tttgccccag ttttccttgg gcatacaaga ttgcaatatt
      961 actttgaagt ggcatatcac gattcaaacg attgtagaat acacctgcaa tgagcttacg
     1021 atcttctgtc ttggcacctt ctttttcgac caaggaagca atggtcaaca actcattgac
     1081 agtcaagttt ttagatttga tagtactata gtaaggagat aggttcttat ccatagcagc
     1141 taacatctca tcaatcaagc tctcaatagt tgtgctttcc ttgatagagt atgtagctgg
     1201 gaaaaggtat ccttccaaac gataacgcgc accgctgtct tttacaggca aactttccag
     1261 taaagtagga tatttcgcta ctgcttgact gataaacgtc tcatcttgaa ctttagccaa
     1321 gaaagcctcc gctgtcaaag actctttgaa gtcaccttgc aattgaccca cagtttgagc
     1381 aatctgatcc aaggtataac cttctggaat tgtcaaagtc gcaagtacag gttcttgcgg
     1441 ttcatctgtt ccaccttttt gcaactcttt gagtaagtct tctgtactca tactcttttg
     1501 caaattgtag taacctgctt tcaagtcggt ataattttta tacttggcat aaaaactaaa
     1561 aatcagacca tgctttacca aaccagcttt ttcaagcgtc gtaccgattt cttgaacgtt
     1621 tgaaccttct ggaattccaa ccgtcacata tttcttagaa ttagcatcga taggtaataa
     1681 ggaatctagc acgtactggt aaccaaagta accacctgct gagagcaagg caaggaatac
     1741 aaggaatgaa atcacaaaag ctttcacatg tgacttcttc tctttcttag gcttaacggg
     1801 ttttgctcct tctctacggc tacgacgtga tgtatctctg atgatatcca ctgtttctgt
     1861 agcaggcgta ggtgtttctg gacctgcttg ttctgctttt ttctctgccg tcgtatagga
     1921 aacagctacc cttgttgggg tttcattgta ttctctttca agtttcttag gtctaacagg
     1981 acctggacct ggtcttgatc cactttcttc cgctggagaa gaaggtacat cttgacttgg
     2041 atgacttgga acaccaggag tttctctttg aatctcatct gctggagaag ctggtacacc
     2101 ttgacttggg tgagtaggca cggtaggagc ttttctcata atctcctcta ccgttgacaa
     2161 ggaatcagcc atgagttctt cagttgaagg ttcatttgca ggagtgcgaa ctactgcctc
     2221 atcttctttc agaacttcat catagccttt tactttttct aaatctctca gaatctgctc
     2281 tttaaagctt aatttctctt cttctcttga cttttcactc aaaagttttt cctccttgtt
     2341 gataatccat aatattatat cttaaaagtc caaaaaaagc aatctatgat acttttccta
     2401 acttattttt tcatttccca gaccatatca taccatgttt cccctgcaaa ggttgactgg
     2461 gactggcctt cgttgacaaa tccatgtttt tcataatagg cgatgagata gtcatgacaa
     2521 gttagattaa tgccatctct ctcatcttca agagcaactt ctttcaaggc tgtcagcaat
     2581 ttctgaccca gtccgagtcc ctgtgcctcc ttggcaatag acagacaggt cacagagata
     2641 taaccaccag gctcatgact atagtctttt atttcttctg taaaagactg gtcttgcaga
     2701 tggcggtgca ggccaactgg tccttcgata taacccatga ttcttccttc tttttcagca
     2761 accagaaaag aggtctgaat ttctctcaaa tgtgcttcaa agacagaagg aggaatggct
     2821 tcttcgaccg aaaaattttc aaattcgagt tcaacaatcc gatccaaatc ttctaatctt
     2881 gcttgtctga ttttcattgt tcctccagat aaaagggatt aaaccaaatc atactatagc
     2941 cctggctagt tgcatagagc aaagttgctt cttcatcaac aaaaccgttc atttcaaaat
     3001 aggaaagcag ctcatcagga ctctccaaac gaatcccttt gtaatccagc tcaactgcca
     3061 cctctttcaa ggctgcaaga agaagtgttc ccaggccctg tctctgatgg tcagactcga
     3121 tgactaaaga atgtactttt agacattgcg gattgtctga ctggggactt gataaaatat
     3181 agcctaaaag ttgattttca tccctagcta gaagaaaggt atccgcacac ttacggatac
     3241 tttcttctaa aatatgggaa agttgctgct tttcagctgg aaaagacgag gtctgaagtg
     3301 cccctatctc aggcaaatca gacttgcttg cctgaatgat cttaattgga atttccatgg
     3361 gaacatccta ttgaacattg cttgtcaagt tagacaagag acgctcaaat gagtattcat
     3421 aggtttggat gtctcctgct cccataaaga cgtaaacagc attgtcatgg tctaggagcg
     3481 gagaaacatt ttcaacagta atcacttggt gttttttgtt gattttgttg gctaggtctt
     3541 ctaccttaac gtcaccatga tctacttcac gagccgagcc ataaatttgc gctagataaa
     3601 cagcatctgc ttggtttaaa gcatgggcaa agtcgtccaa caaggcaatg gttcttgtaa
     3661 aggtatgcgg ttgaaagact gctacaattt ccttgcttgg gtatttctga cgagccgcat
     3721 ccaaggtcgc aataatttct gttggatggt gggcaaagtc atcgataatc actgtatcat
     3781 tgacaatttt ctcagtgaaa cgacgtttaa caccggcaaa tgttttcaag tgctcacgca
     3841 ccaagttcaa atcaaatcct gctgtgtaaa gaagaccaat aacggctgtc gcattcatga
     3901 tattgtgacg accaaaggtt ggaatgtgga attgccccaa gttttgtcca cggaaatgaa
     3961 cggtgaaggt tgaaccagtt attgaacgaa gaagatcact agctacaaag tcattgcctt
     4021 caacttcaaa accataataa taaattggtg catcagacgt aatcttacgc aattcagcat
     4081 cttcaccata gacaaaaaga cccttggtga tttgtttggc atagtcgtta aaggcattaa
     4141 aaacatcctc gagacttgtg aaataatctg gatggtcaaa gtcaatgttg gtgataatag
     4201 agtattctgg gtggtaaggc atgaagtgac gctcatattc gtcagattca aagacaaaat
     4261 atttggcatt ggccgaacca cgacctgtcc catctccaat caagaagctg gtatctgtaa
     4321 tgtgagacaa gacatgagac aacatacctg tcgttgaagt ttttccatgt gctcctgcta
     4381 ctcccatgct aacaaagtca cgcataaagc tacctagaaa ctcatggtaa cgtttgtagc
     4441 tgataccatt ttggtccgca taggcaattt cgacgttgtt atctggacga aaggcatttc
     4501 cagcgataat ttccatatca ccgtctagat tcttttcatc aaaaggaaga atggtaattc
     4561 ctgcctggtc aagaccgcgt tgggtaaagt agtacttttc aacatctgat ccctgaacct
     4621 tgtgccccat ctggtgcaac atcaaggcca aggcactcat ccctgatccc ttaattccga
     4681 taaaatgata tgtctttgac atgttttctc ccctattctg tcattctggt cagattcaac
     4741 tcttgggcaa cccgacgttc ttgttctgtt tgtttacttt ttttattgta gatttggctc
     4801 ttctttagaa aatcataatt gtttttcttt ggagcaggtg ctgacacttc ttcattcttg
     4861 gtagggatag aatgaacttc ttccgccaag atataatgag actgggtcaa tttttggcta
     4921 tatttgacaa attcaccagg attttccttt tggaaaggag ctgtcggttg attgccctgt
     4981 ctaactagac tgggctgaga atgacgtctc gcaaggctga aatcctgagt taggtagtta
     5041 gcagagcgtt tctttttcaa gtctgcacgc gcttcttcac gcgccacctc cgcatagctc
     5101 tttccttctt ttttaacccc taaaggagcc tttttaggtt tttcgacttg cttttcaatc
     5161 ggttttactg gtttttcttc agtaatagga gcccattcta aataattttt atctcgatac
     5221 tcacccttga tattactgat cagatcagac tcatcataga gattcatgac tggcatttca
     5281 gtcaacatga cctcgtcatc tgacaccaat ggaaatcgtt cttgtttcat tttctatttc
     5341 ctttcaacac ttcattatag cgtattgtct tgatttttca agtgctggct tcagaaattc
     5401 ccaaaatttc tctaatttct gctagggtca gactaccacg tgactctgtg ccatccaata
     5461 cttgtgacac cagatgtttc ttttgttctt ggagttcctg aattttttct tcaatggttc
     5521 ccttggtcac caagcgatag acctcaaccg tttcttcctg acccatccga tgggcacggc
     5581 caatggcttg cgcttccacc gcaggattcc accaaaggtc aaccaagatt actgtatctg
     5641 cacctgtcag gttcagaccg accccaccag ccttgaggga aatcagaaag gcatctcttt
     5701 ctccttggtt aaaggccttg gtcatgtctt gtctttcctt ggatggggtt gaacccgtaa
     5761 ttttaaagga agtcaggccc aagtctggta gttcttgttc aattttttcc aacattccct
     5821 tgaactgaga gaaaatcaag acacggtgtc cgccgtctgc cacctgtacc agtaggtctc
     5881 ggagactatc tagtttgccg ctggctccct gataatcttc cataaacagg gcaggagtgt
     5941 cacatatttg acgcaagcgc atcaaaccag ataaaatttc cacacgactt cgctgaaatt
     6001 cctgttctga cacttgagcc agatggtctc gcatctgttg taactgggca aggtaaatag
     6061 ccttttgctg gtcttccagt tcatttttat aaaccacctc aatcaagtct ggcaattcag
     6121 tcagaacttc ttctttcttg cgtcgcatca cgaaaggctt gataaactga gccactcgct
     6181 ctgctggcaa tttcataaat tctttcttgc ttggcaaaag tccgggcatg acgatttgga
     6241 aaatagacca caactcaccc agatggtttt caatcggagt tcctgacaag gcaaagaccg
     6301 acggcaccac aaattgtctc aaggtctggg caatcttggt ctgggcattt ttcatgacct
     6361 gagcctcatc taagaaaagg aagtcaaagg ccatcccctg ataaaactca ctgtcctgac
     6421 ggaaggtggc atagctagtc acatagattt gatggctctc ggcaagaatc tcctcacgac
     6481 ttgctttcaa accatgaaca acagccacat ccaactgtgg ggcaaatttc tgaaactcat
     6541 ccgcccagtt gtaaatcaaa cccgacggag cgagaatcaa gactcgactt tcttttgtca
     6601 cttgactagt caaaaaagca atggtttgaa gggttttccc aagtcccata tcatcagcca
     6661 aaatcccacc aaaaccataa tgatggagca tctgcaacca gccaattccc ttttcctgat
     6721 aatctcgcaa gtcagccttg acctgagttg cttgcaaagg aaagtcctct ggatgcgtca
     6781 aatcctgggc cagattctgg aattcttgtg aaaaagaaac acggtctcgc ccttcaaaga
     6841 gatgagctaa actgtaggcc aaggatttcc gagcctgcaa ggtcccatct tttaattcaa
     6901 attgccccag ttcctgtaga ttttggcgaa ttttcttggt ttcttcatcg aaaaagtaaa
     6961 cttgattaga cgaatcaata taaaaatcct gattggcaac caaggcctgc atggcttggt
     7021 cgatttcctc ctgggcaata ttttgaaaat caaactggat ttccaagaga cctcccttgg
     7081 aggcaatctg cacctgagga ctcgctaggc tataaagctc ttctagttta tctgataggt
     7141 caacatgccc gagtttttca aagactggaa tgatatcatg aaaaaaatga tagacagact
     7201 ccgcttttaa ggcctgacgc caagattgaa aatcggcttc aaagcccgca gccaaacaga
     7261 cttggaaaat tctttcttct aagtctgcgt cacttgaaaa gggtaattct tctagctctt
     7321 gtcggctaga tacctgtcta tttccataat caaactgaat ttctaaacga atccgattat
     7381 cttcttccct gtcaaagtaa aaagagggcg caaaagtttt gatttgtaga cgttctggag
     7441 ctgaaacggt gcccatctgg ataaaaagag tcagacagga ggccaatttg tctcgatcac
     7501 tgctatcaaa ttgcaggtat ttctttcctt gttgacccac aggtaacgct ttaatttcct
     7561 tgagaagacg catctgctgg tctgttaaaa aataaacctg acctttatgg aaaagtactg
     7621 ctccctgata aaagacattg accctaggac tctcactgat ttccatttca aaataatccg
     7681 agtattctgt tactgcaaag gcaaatagat tggcatcagc atgcatatcc tgaaaaagca
     7741 gggtttggta gctatccact tgatggtcaa attgaaaatg gggcaaggcc atcagtaaat
     7801 tcacaccctg ctcaaaaaag gtcagaggga aaaagaggtg ccgaccttgg ttttggaaaa
     7861 agaggtctgg aaccagccct tcctccgtta gtccgtgcaa gaaagtcaaa agttcttggc
     7921 tggcatcatc aaaggcttcc caagaaagag actcctcata aatcttgcca atcatatacg
     7981 actttctctg ctcgacaatc cttaaaaaaa gtggaatatc ccgaatgata tagtattttt
     8041 ggctattgat ttggccgatt ctcagagtcc acaagatatg attggttcct gcttccacct
     8101 gacccacagc tgataactca taggcgcatt ctgattttgg agataaaatt cgatccaaaa
     8161 acttgccacc caaggtcacc ttggtttcaa cggcctcttt ttcttcatga ccttcttcca
     8221 gactccacaa gatttcctga ccacgctcat catttttcag aaaatgctct agcgctgcca
     8281 aatgcacaca gtagcccctc ttttgaaaag aatcacaggc acaaaaaacc aaatcatcct
     8341 ctaaactata gcgcagttct tcttctgcaa cgcgagcgta gagccgattg ttcttttcct
     8401 tgatgatatc aaccttacca gtttcataaa gggcaacacc ttcgatacga attttccccg
     8461 gaatcaattt agccatattt tcacctttac cttatctttt tattatacca tattttcgcc
     8521 tatgaaaata gccttctagg aagacttttc tcctagaagg ctggattttt aacatttggc
     8581 aaaagtagcc acaatccgct gacagacttc ttgcaacaga gatttgggca tagctatatt
     8641 gatgcgggca tggagacttc cttcctctcc aaaatccaaa ccacggttga ggataacctt
     8701 ggcttcattt ctcaacaact cttgcaatgt ttcatcagtc aggtcataag ctgaaaagtc
     8761 aagccaaatc aagtaggtac cttgcggttt catgaccttg attttagtct cttttccaaa
     8821 tagatccacc acataattga tgtggtcttc aaagacttgc ttgagttcct ctagccaatc
     8881 tttaccgtat cgataggcag cttctgtcgc caaataaccc aaacctgaaa tttcatgctg
     8941 attattggcc aacaggcgtt tctggaaagc cagtctcaac ttaggatttt caattactgc
     9001 ataggaattt tttgttccag caatattaaa tgttttagtg gcactgctca agacgatagc
     9061 aaaatttttg aaggcaggat tgatggtatt gaaagactgg tgtttgtgac caaagagggt
     9121 caaatcttgg tgaatctcat ccgaaactaa caaaacaccg tgtttttggc agagttggcc
     9181 aatcttctcc aacacttctt tttcccaaac acgtccacca ggattgtgag ggttgcaaag
     9241 aacatagagt ttaacctcct cttccaccaa atccttttca agttggtcaa agtcaatctc
     9301 aaacagacta tccttttcca ctaaggaatt agtaatcaat ctacgattat tcaacttgac
     9361 actgcgagca aagggtgggt agacaggcgt gttaattaaa accgcctcgc cttcttttgt
     9421 aaaggtttga atagctgttg agatggctgg taccacaccc tcgataaaga caagagcctc
     9481 tttgtcaaag ttgtaaccgt attgtgtagc ttcccacttt tgaatttcct taattaagtc
     9541 ttcactggca taggtataac cataaaccag ttggtctgcg taagtttgca cggcttggcg
     9601 gatttcaggc aagaccacaa agtccatatc cgctatccaa gctggtagaa cttcactatc
     9661 cgtttctgtt tctttccatt tataggtatg gtgccctaaa cggttgggca ggcttgtaaa
     9721 atcatatttt cccatctttg tcttatcctt ctatggcttg gcgcaaatct gcaatcaaat
     9781 ctctagcatc ctcaatccca atagacaaac gcaagaggtc atctgtcaaa ccataagaat
     9841 ggcgtacctc tgctggaata tcagcatgag tttgagtcgt tggataagta ataagacttt
     9901 ccactccacc caaactttcc gcaaaagaga agaccttgag actgttcaaa atatgaggaa
     9961 tgcgtgtttc atcggctact ttaaaggaaa tcatgcctcc acgaccagtg tagagaactt
    10021 ccttaactgc tggagaatcc ttcaaaaagg caaccacttc ttgggcgtta gctgttgagc
    10081 gctccatacg aagagacaag gtcttgagac cacgaagcaa ctggtagctg tcaaatggag
    10141 acaagactgc ccctgttgta ttaagattgt aaaaaagctt ctcgtatagt tctaaactat
    10201 tggtcacaac cactccagcc aagacatcat tgtggcctgc tagatacttg gttgctgaat
    10261 ggagaacgat atctgctcca tcttcaatcg gacgttggta gatagggcta tagaaggtat
    10321 tgtccaccac cactttggca cccttagcat gagccaattt tgctagtttt tcgatatcaa
    10381 attccaacat caagggattg gttggggttt cgatatagag aacatccaca tccttttcta
    10441 actcggcaat caactcttct tctgtattgg cataggtaaa atggaaatga ccttcctgct
    10501 ccacttggtt aaaccagcga aaagaaccac cgtaaagatc acgcactgcc aagaccttac
    10561 ttcctactgg aaagacgcta aaggccagta caatagctga catccctgag ctagtcgcta
    10621 aggcatagtc tgctgactca atagccgcca agacttcctc agccttacta cgagttggat
    10681 ttttagtgcg cgtatagtca aacccagtag atcgaccaaa ctctggatgc tgataggtcg
    10741 ttgaaaaatg aagcggtgtc accaatgcac ctgtcgcttc atctgactta atacccgcct
    10801 gggccaaaat tgtgttaatg tgtaattcct tgctcataca atacctccaa atctatagta
    10861 actattgtac cacttatttt catcaactca ttttcttctt ttcaagagct agttatagtt
    10921 tcaaactata taaaaaggga gtttttcctg ctccctttaa tagactataa aatggtgaat
    10981 ctcaaaagac acttcactct atcatttgct cctgcacaaa acgagcataa cgctcatgat
    11041 tttccagtag ttccttatga gttcctgagc cagtgatttt cccctcctct aagaagaaaa
    11101 tacaatccac atcttttacc gttgacaaac gatgcgctat aatcacaacc gtcttctcct
    11161 ttaatacaga atagaggcta ctgataatcg catactcaga atccgcatca agattagcag
    11221 tggcttcatc aaatataaga atttcagcat cttttaagta ggttctagct atttgaagtc
    11281 tttggctttg cccccctgac aagaatcgtc cgcgttcacc aacttcagta tctagtccct
    11341 ctttcatgga gcgaatctca tcacctagtg atactaagtc tagcactttc atcaattcat
    11401 catcagttac taagcgattc aaaccgagac aaagattgtc acgaatactg ccagataaga
    11461 ctgcattatt ttgtgaaacc caagcgattt tacttctcca ctcttttaag ttaaaatcat
    11521 atatacttga ttgctccatt agaatatctc ctgaaagcgg tttataaaac cgctctaaca
    11581 aacgcacaat cgttgatttt cctgatccag atggtccaac aaaagcaatt ttttgcccct
    11641 tgaaaattga acaagtaata tcctttaaga caggtcgatt ttcatcataa ccaaaataga
    11701 catggttaaa attcaaccct tgtcctgata ccgattttcc tcactcaaat ttttctttag
    11761 gaactgcaag caagttctcc agtgcaactt aagatccctt gctcctagaa taaacagtta
    11821 caaaattagc tatattacta ataggattaa gtaattgaaa gaggtaaatc aaaaacgaaa
    11881 ccaaggttcc cacagatata tatcctgcgc tgacccgata actcccatag gttagcatca
    11941 cagctatagt cgcaaagata aataagagag caaacggggt ctcaaaagaa gtaaccctat
    12001 ctgatttcag tgaattgttt tgtacccttt caatacaatt atccaaaaca ttctgtacac
    12061 ttttctctgc ttggttagtc ttaattaatt catgttcttg aatcttttca gtcaattgcc
    12121 ctgttaaaaa tccgatttcc ttctgtaaac gacgactata cttttcactg atattggaaa
    12181 ggggcaagat aataaacatc atacaaggaa gagtgatgaa taaaagtaga gaaagattcc
    12241 aatcaagact aaataagact acaatggaac caagtaccat aactaaactc agaataatat
    12301 ttgggaaagt cgtaattaaa aactcacgaa tgacactcat gtcattgaca atggcagaag
    12361 tcaactcccc actttggctc ttatcaaaga aggatttctc tgcataaatc aacccctcta
    12421 tcactttttt cctgattttt gctatctttt tttcacccga ttgactaaac agatagtaac
    12481 caatagaaga aaacaaggct tgaccaataa aaatcaaaaa cgattgaaat actttggaac
    12541 ctatattttc aatagaactc ccatctatta aaccctttaa gataagggga agcaacaaag
    12601 caagtagact agacagaaca agtaagaaac tccccataat caccttagta tctactctta
    12661 ataattttaa tttcataaat actccttata atatttcaac ggataaagtc gagaataact
    12721 caatttgagg ataaaatcta ataaatcttc ctataacaaa acgcataaca tctaggattt
    12781 tatatacctg atattatgcg tttttaagca caaagacttc ttacacaaac ttatctacaa
    12841 ttagatttta tttgacatgt tttgccaatt cttcttgggc ttttttattg gattcttctt
    12901 tttctttcaa ccatttttct ctggcttttg catattcgtc tgttgtgaca atcttatctt
    12961 gtactttgag gtatttatat gattcaaccc ctttattacc agccaatgaa taaggtgctg
    13021 agaaaggaac tgtttttctc aagctaggcg ttccacctaa tgaaacattt ggaatcgcta
    13081 gagaactatc tatcaaccat gcttgaatat cagcatattt ctcataacgt ttggctgggt
    13141 cttgctcctt attagcctct tccaacattt gagtataagt gtcaagtcca actgccttag
    13201 ccttgtcatt ggcttcacca gggtcgagtc caagattttg tagaacccca ccattcttga
    13261 cactaaagat atcaagatag gttgatggat ctaagtagtc aggactccaa ccaccattgt
    13321 aaaggtcgta gtctttctga atagcagtct gagcaaggta acttgagtta tcatagtcct
    13381 ctgttgataa ctgttggata tcaataacga cgttctccgt acctaaagct gcttcaatag
    13441 attgcttcat agagcttact tcttgaatcc ccttcttaga agcttggtca actgtcgcat
    13501 ccaaatgaat agggaattga actcccttag cttctagctc tttcttagct tccgcaaatt
    13561 tagccttggc tttctcagga ttgtagtaag ggtcttgacc atccgcaaag ttgatgcctt
    13621 gccattcctt accataatta ttgaccatct tagaggctac tacttcacca aaatcttttc
    13681 ctttgatact tacaaaggtt ggaggaacaa ccaagttacg caaaatctta gtcgctccgt
    13741 cttctccctg agtttgagcc ccataggagg tacgatcata ggcaaagtta atggcttgac
    13801 ggaagttttt attaagaact gcttcctgag ttgatttctt ttcaatgtcg gtcgtcttag
    13861 aagtaaattt ataagcttgt ctatctaggt taaaattcca gtaataagac gtagcatcct
    13921 gcatactgta gatgatatca tctttgtatt tttctttaat cccttcaaaa cttgaactat
    13981 tcggatagag acgggcatag ctataggctc cgtctgtaaa gttacgaaca agagcatctt
    14041 ggtcactacc atcatagtag gtcaatttca catcgtctac aaagacattt ttagcatccc
    14101 agtagttagg atttttcttg tattcgatga cagattttga aacaaaagct ttcatcaaga
    14161 aaggtccact gtacaaaata ttagcagggt ctaccttgcc aaaatcatcc ccttttgatt
    14221 tcaagaaatc tgcattgact gggaaaagaa tggttgaggt tgtttttgag ttccagtaag
    14281 gttctggtcg agccaaggtg tattgaacgg tttgatcatc aagagccttg ataccgacag
    14341 ttgaaaagtc gcttgtttta ccagtgatat agtcatccaa acctgcaaca gagtcctgca
    14401 ctagatacaa ggcttctgat tttttatcag ctgcatattg caatcctgtc acaaaatcct
    14461 gggcagttac aggtgcatat tcttctccct cagaagtaaa ccacttggca tccttacgaa
    14521 gtttgtaggt ataggtcaaa ccatcctgag aaacagtcca atcttctgcc aaggatggca
    14581 catagttccc atattggtca ttttccatga gaccatctac cagattggtc acaatatcat
    14641 tggttgttgc gcggttttct gctagatagt tcaagctaga tggatcactt gaataaacat
    14701 agttgtaggt ttttgacgcc gtgctagaat ttccacacgc gctcaataaa actcctgtac
    14761 ccaggacaag acctgccaag gttagatatt tgctcttaga ctttttcatt tccggaacct
    14821 cctgctttaa acatttgttt tattatacaa ctcttggttt gtttagtcaa ttgttttttc
    14881 caaaaaatca aaaaaaacct cattttctat ttttgaaaga taattttagc tatttttacg
    14941 ctaaaaaagg aataagtttc aagttctcct aaaagattgt tcaacttatt ccttttattt
    15001 ataaatgcta ccttacgaaa gcttaaattt tgctcgcagg cgatctgctt gggcttttcc
    15061 tattacctta tctaacaaat aggtacgcag actcataacc atataaagtc caccccccat
    15121 ggcaccgaca agagctacat aaaagaagct ccacaaacgt ccacttggtt ggaagaaaaa
    15181 tcctaacagc cactggatgg ttcctattaa cagaaacatg actagggtca gcaaactgat
    15241 taaaatggtt cgcttcaaaa tcaccttgcg cttgacacca gttactttac aaatatcccg
    15301 atacatcaag acgttaggaa tgatgagagc aatggttgtt gaaatcaaag gaccataact
    15361 gtggaagagg gcgatggtag gtagttgcaa gactagcttg gcaatagaac catagataaa
    15421 atagagaacg gccttgcggt tgcggaacat ggcctgaagc attggagaca agaccatgta
    15481 caagcctaaa ataatagact gcaaaactgc aaagacaaat aagcccagag ccaaactatc
    15541 tggcttacca tagaagaccg tataaagagg ttctcctacc ataaccactc caaccgttgc
    15601 tggtagcaag aacataaaga gtagggtgag actgtcctga acgagacgag aagctgcttt
    15661 caagtccccc ttgacatagt tttccgtcaa aagtggcaaa ccaacactcc caatcgaaac
    15721 ccctacagaa atcaaaatca tcgtgatttt attaggattg gctgagaaat aagaaaacat
    15781 gacaaccaag tcctcattgc tgtagttggt aaaccagctc atactattga taaaggtcag
    15841 ctgatccaaa atctggaaga gctggatggc agaccctgtc aggataaaag gaatggcttc
    15901 cttaatggta tcaaccaaga gacgcttact gttaatctta tctcctgttt caaagactct
    15961 tttgagtgaa ccttcttggg caaggaaata aatcaagact gcaaaactgg ctaccatacc
    16021 gacaaaggca gcaaaggttg attgggtaac ggctgctaga taatctcctg aaccgagctt
    16081 cataatgata aaggttgcta ggagcatcca gataacacga atgacctgct cagcaatttg
    16141 gctcatggca tagggtttga ggttattcat cccttggaaa aatcctcgga taacactcat
    16201 agacgggaaa atcaagactc cccaagccaa gctttgcatg attgggatca agtctttgcc
    16261 cacgccagac aagtctgcta gccaaggagc aaagacatac aagactaaag caaaaaccag
    16321 gcctagtcct gtcataaagc ctaagaagct ccgaatcagg gcaaagctat gctcttcttc
    16381 tcgcatggta ttatacttgg caacttgctt ggccaccgca actggaatcc ccgctgttga
    16441 aaccaacaag aaccaagcat agatattgta acccatggta aagagaccat ttgccttagc
    16501 tgcataagcc cccatccaga tgtaccaagg gataatgtaa acagccccga gtaggcgact
    16561 gataaagtta ctagccgtta gccaagcagt cccccgtaac atctgggcct gctggtgatt
    16621 gttttcgtgc gacatagatt cctcattcaa ttttgataac taggaaaaac tccttatctt
    16681 ccattataaa cttttccttg ttacttgtaa atttgcgact ttcggtttac aatagaaagt
    16741 atgataaaaa ttgaaactgt attagatatt ttaaagaaag atggcctttt tcgcgaaatt
    16801 attgaccaag gtcattacca ctacaactac agcaaagttg tttttgatag catcagctac
    16861 gacagccgaa aagtaacaga agacactctt ttttttgcaa aaggcgctgc ctttaaaaaa
    16921 gaataccttc tttctgctat aacacaaggc ttagcttggt atatagctga aaaggactac
    16981 gaagtcggta tccctgtcat cattgtgaac gatataaaga aagccatgag tttgattgcc
    17041 atggagttct atggtaatcc acaggaaaaa ctcaaactcc ttgcctttac tggtactaag
    17101 ggtaagacaa cagcagccta tttcgcctat aacatcttat ctcaagggca tcgacctgct
    17161 atgttgtcga ccatgaacac aactcttgat ggagagactt tctttaagtc agcgttgaca
    17221 acccctgaga gtattgacct ctttgacatg atgaatcagg ctgtgcaaaa tgaccgtacc
    17281 cacctcatca tggaagtctc cagtcaagcc tatctggtca aacgtgtcta tggtctaacc
    17341 tttgatgtgg gagttttcct aaatatcagc ctagaccata tcggcccgat tgaacaccct
    17401 agctttgaag actatttcta ccacaagcgt ctcttgatgg aaaatagccg agcagtcatc
    17461 attaacagtg acatggacca cttctcagtc ttgaaagaac aggttgaaga tcaagaccat
    17521 gatttctatg gtagccaatt tgataaccaa atcgagaatt ccaaagcctt tagattttca
    17581 gctacgggta aactcgctgg agattatgat atccaactca ttggcaactt caaccaagaa
    17641 aatgcagttg ctgctggact tgcttgtctc cgtctcggag caagtcttga ggacatcaaa
    17701 aaaggcatcg ctgcaacccg cgttcctggt cgtatggaag tcctcactca gaaaaatgga
    17761 gccaaggtct tcatcgacta tgcccacaat ggggatagtc tgaaaaaact catcaatgtg
    17821 gttgaaactc atcaaaccgg aaagattgct ctggttctgg gatcaacagg aaacaaggga
    17881 gaaagtcgtc gtaaggactt tggcctcctc ctcaatcaac accctgagat tcaagtcttt
    17941 ctgactgctg atgaccctaa ctatgaagac ccaatgggca ttgcagatga aattagtagc
    18001 tacatcaatc atcctgttga gaagattgcg gatcgccaag aagccatcaa ggcggcaatg
    18061 gctatcacaa atcacgaatt agatgcagtt attattgcgg gtaagggagc cgattgttac
    18121 caaatcatcc agggcaagaa agaatcctac ccaggagata cagccgtcgc agaaaattat
    18181 ttataagaat agaaaaaatc aagggaaaat gaaacccttg attttttcct attatttagt
    18241 aaaaacgttt ttcaaacctt ctacagcacc ttttgcgtct tctacaacgt cttttgcctt
    18301 agcaactgtt ttttcaacag ctccttcaag ttctgtcttg ctgtctccag taactttacc
    18361 aaaaccttct ttgacagcgc ctgttgcttg ttccaatttg ttttcaagtg acatatgatt
    18421 gtctccttta gtttattccg atatgtgtta ccggttacat atagtttata ccgaatacta
    18481 aggaaagtca aacaatgtac tcagaaacaa gaaatcacgc taagtagaaa gttaatctct
    18541 ccttatcaaa atcgatagcc aactcatact ttccatcttc attttgcaca atatagccta
    18601 agacaaccaa actgtccaca aagatatcac ggcatttctg cataagctgg tcttttttga
    18661 gaaatttcaa caaaaaagcc gtcatatact tgagggcata ctcaggatta acatctccta
    18721 aaatgtcata gagctcctgc tgtttttctg tcaaaggata ctgctgtttg accttgtaaa
    18781 aataattgga cagggtcatt ttaatgcgcg caaagtccgt cttttcaact aaaatagctg
    18841 cattgatttg attgcgcaat tccgtctcaa aactctgctc caacaaggct tgatagaccg
    18901 gactagcttc tctgacaaaa atctcttgat ccagttcaag actatcaagt gattcaagcg
    18961 taggaaaatt aaggtaatag cgcttatttt cacatagaat cacatcctca tactggtcca
    19021 gatagcggat caattctcca aaaatggctg tctcgtcaaa cgagatggat taaaaatctg
    19081 aatcacgaag attcctttct ttacattgta acagaggcga tgctgccaac tgactaggat
    19141 tggtcccagc ttggttcaga ggaacaggca gacctagttc tatgtaatac tccctccaaa
    19201 aatcactaat ctcctgttcc ccatctccaa atttcatagg aatagtttca aaaataggta
    19261 ggatttctgc tatatactgg gagcagtaga aaccagctgc atctggatag aaagaagcat
    19321 tgtagggtgc tccaagatgt ttgcaagctc tttccttcac cgactggata tccatttctg
    19381 ggtaaacata gaggtcgtat aaatgattgg actcaaagaa gtctgccggt tcttgacaga
    19441 caacaccagc ctgtccacta gcatgataaa tcatcccatc caaataaatg gcaacatggc
    19501 tatagttacc tgtggaagtc tggatggcct gtcccatgtc tgacccatct ctcacaaaaa
    19561 tcaaatcgcc attttctaac atacttcact cctagaaaaa aggagccgaa actcctttcg
    19621 atataaggca aactagactt tccgattttg agctgacacc caaaatctta cgcattaaag
    19681 ctttcagtca attgaggtac cacttgtttc ttacgtgaaa cggcaccagc aaggaaggca
    19741 tgattgtttt caagtttgaa gttgaaagcc gcttcgacct tgtccatatt ggcaccaaga
    19801 gccaagattt ctgagtttga gttgacgata tctgtaatca tcaagacaaa gtcagagtag
    19861 ccgtttgatt cgttggcagc ttgcattgca gcttcaattt ctgcttggcg ttccaaaact
    19921 tcagcgatgt caactgtgtt cacttgggca acacggacat tatttccgtt gagttcaaaa
    19981 gtcttagcat cgatgtcaat caattcttca gcagatttgc tagccaagtt ggtaccagct
    20041 ttcaacattg ccaaaccata ttcttccaag ttcacaccag ccaattcagc caattcagga
    20101 gcaatgattt tatctgttgg gtgtgttgtt ggtgatttca aaagaagggt atctgaaatc
    20161 aaacctgaaa gcatcaaacc tgcaatctct ttaggcacag ctacaccatg ttctttgaac
    20221 atacggtaaa cgattgaaga cgctgatcca actggctcca aacgcatgta aagtgggctt
    20281 gcagtttcaa agttagccac acggtggtgg tctacaacac cgtaaacttc tacttcagcg
    20341 atatctgata cagattgttg gaattcattg tggtcagtca agataacttg ctctgccccc
    20401 tctgctttgg cagaagtgat aacacgtggt gcttccacac caaaatagtt caagacaaag
    20461 gctgtttctt catttggagt tccaagggca acagcttccg tatccaaacc gtaagcttct
    20521 tttgcaaggt aggcaaaagc tacagatgac ccgatggcat ctgagtctgg attttggtga
    20581 ccaaatacta gaatcttgga catgataata cctcattttg tttattttct ttattgtagc
    20641 atttttttcg ctttttgaca aaggtaagag gagtcaaagg actccccacg attcttcaaa
    20701 ataactgagt aaatttctat cttgattttc agataaaaat tcttccttct gtggcctctt
    20761 cttacgcttg agaagagctt cagccgacat ggcttcttcc ttactggcaa aacctttata
    20821 tttggctccc ctcccactat tgtggatagc gaggcgtctt ctcacatcag tcgtatagcc
    20881 tatatagtag gatccatcac gacactccag aacgtacata taagccttat gatccataat
    20941 aaatctcttc gatttcgggc gtataagagc catcatcatt gtggacaatc aaaggaggta
    21001 agaccttaaa gccacttgtt gagccatcct tgattgcctc aatcaaaagc atattggctt
    21061 ccttttctct ttttggataa acaaactgca ggcgcttagg ggctagatta tgtcgtttta
    21121 acgtatccaa aatatccaga agtcgatcag gacgatgaac catggccaaa cgcccattag
    21181 acttgagaat actctgagca ctacgacaga tttcttccaa attagtcgtg atttcgtgtc
    21241 gagccaagag ataatgttca ctctcgttca gattagaata aggatccacc ttgaaatagg
    21301 gtggattaca caaaatcata tccaccttac tcccctgaat gtgagctggc atatttttca
    21361 aatcatcgca gatgacctgc atttgctcct ctaatccatt caaacggaca gagcgttcag
    21421 ccatatccgc caaacgctcc tgaatctcaa cagacaatat ctgtgcttga gtacgagtgc
    21481 tagcaaaaag ccccactgct ccattcccag cacagaaatc cacaatcaac cccttcttag
    21541 gaaaacgtgg aaatcgtgat aagagaacac tatccaccga atagctaaaa acctctctat
    21601 tttgaatgat tttgatatct gtcgaaaaga gctggttaat gcgctctcct gattttaata
    21661 attgttcttc ttccatggtc ctattatagc aaatttatat taacattaca aaaaatataa
    21721 aactctaaac tacttcttct tttttaaatg gtgcagggct tctccagtcc agattggtaa
    21781 cattcgtcga aagggagcaa aaccgtagtt aaagcggtcg cttgaaaagc gtctccgtct
    21841 aggaaactgg tacttttctt cctccaaagt gcggatagaa agactggctt tccccgtaaa
    21901 ttcatctaaa tccactacct gaacttgaac ctcttcatcg actttcaagg tttcatgaat
    21961 attttcaata aatcctgtcc gaatttctga aatgtgaatc agccccgtat cacccgtctc
    22021 taactcaaca aaggcaccgt agggctgaat ccctgtaata cgccccttta gcttatcacc
    22081 gattttcatc ttagtcctcg atttcaatag tttcaattac aacatcttca actggcttgt
    22141 ccatagctcc tgtctcaaca gcagcaatgg catccaagac agcgtaagat gcttcatcag
    22201 ctaactgacc aaaaaccgtg tgacggcggt ctaggtgagg tgtcccacct tgattggcat
    22261 agatttctgc aatcggttct ggccaaccac cacgagtaat ttctttctta gaataaggta
    22321 ggtgttggtt ttgcacgata aagaactggc tgccgttggt atttggacca gcatttgcca
    22381 tggaaagagc accacggata ttgtaaagct cttctgagaa ttcatcctca aaagattcgc
    22441 cgtagattga ctcgccaccc ataccagttc cagttgggtc tccaccttgg atcataaagt
    22501 ccttgataat acggtggaaa atgacaccat catagtagcc atcttttgaa agagatacaa
    22561 agttagccac tgttttagga gcatgttcag ggaaaagctt gatacgtaag tctccgtgat
    22621 tggtcttaat agtcgcaaga ggaccttcta ctgtttcaat gtctacttgt ggaaaatgca
    22681 attctttttc taccatacca aatacttcta aggcagcaaa aatgccatct tcttctaatg
    22741 tttttgtaat ataatctgct ttttctttga ttttatcatg agaaattccc atggcaacgc
    22801 tgattccagc ataatcaaag agttccaagt cgttgagacc atctccaaaa accatgacct
    22861 tctctggttt caagccaagg tgttccacaa ccttttccac ccccgtcgct ttggagcctg
    22921 aaatcggcac aatatcagac gaatgttgat gccaacgaac catgcgaagt ttgtctgaga
    22981 gactgtcagg caagtgcaag tcatctccct tatcttcaaa agtccacatc tgatagatat
    23041 cttctttttc atggaaatcg ggatctacat ctaagtcggg ataaattgga ttgatagctt
    23101 cactcatcat atcggtgcga gtcgacaact tggcatcatg actcccaacc aagccatact
    23161 caattccttc ttgcttagcc caagagatat actcctcaac atctgacttt tcaatctgat
    23221 gctgataaat gacctgacct tttttatctt cgatataagc cccattcaaa gttacaaaaa
    23281 agtcaggctt gagatcacga atctctggaa caacaccaaa aatgccacgt ccagaggcga
    23341 ttcctgttaa aattcctttt tcacgcaact gtttaaaaac agtgggaatt gtagttggaa
    23401 taaaccctgt ctttgaattc cgcaatgtat catcaatatc aaaaaagaca atcttgatct
    23461 tctttgcctt gtatcttaat ttcgcgtcca tctcactacc tctttcaatc taactctttc
    23521 cattatatca taaagtaggc aaatccccta ttttcaaaaa gtttatcatt tttattttaa
    23581 tttcttggat gagaaaagag acatatttat gaaaaagctc catcgtgctt ttaatgtgtt
    23641 ctcttgtttt caaactcgta aaaagggagc cactgagcct gactcgctct ctcatttcaa
    23701 agcttgtgaa aaaagacccg ttggggtctt aattcgcttt cttgttttca agctcatgaa
    23761 aaagagaccc aaccgggtct tttctttaat cttcgtttac gaaaggcatc aaagccatta
    23821 cgcgagcgcg tttgatagct gttgttactt tacgttggtt tttagctgaa gttcctgtta
    23881 cacgacgagg aaggattttc ccacgttctg aaacgaaacg gctaagaagc tcagtatctt
    23941 tgtaatcaac atattcaatt ttgtttgctg cgatgtaatc aactttttta cggcgtttga
    24001 atccgccacg acgttgttga gccatgtttt ttctccttta taagtttagt tgtccattag
    24061 aatggtaaat catcatctga aatatccaat gggtttgttg ctccaaatgg attttcatta
    24121 cgtgaaaagt ctggtactga atttgtaggt gctgaatagt ttgcagttgg tgcagagtaa
    24181 gctccacctg tgtgaccctc acgcacacta cggctttcca acatttggaa attctcagcc
    24241 acgacctctg tcacgtagac acgttgtcct tgctggttat cgtaactacg agtctggata
    24301 cgacctgtca ccccgataag tgagcctttt ttagcccagt tagcaagatt ttcagcctgt
    24361 tggcgccaca taacgacatt aataaaatca gcctcacgtt caccattttg actcttaaat
    24421 gtacggttta ctgcaagagt aaaagtcgca actgctacat ttgatggggt ataacgcaac
    24481 tcagcgtcac gtgtcatacg ccctacaagt acaacattgt taatcatagt ttaccttctt
    24541 acgcgtcaat tttgacgatc atgtgacgaa gaatgtcagc gttgattttt gaaagacggt
    24601 caaactcttt aagagctgca tcgtcatttg cttcaacgtt aacgatgtgg taaagtcctt
    24661 cacggaaatc ttggatttcg tatgcaagac gacgtttttc ccaagttttt gattcaacaa
    24721 cagttgcacc gttgtcagtc aaaatagagt caaaacgtgc taccaaagcg tttttagctt
    24781 cttcttcaat gtttggacga atgatataaa gaatttcgta tttagccatt gatatgttcc
    24841 tccttttggt ctaatgaccc caagactttg caaggggtaa gtgaggttcg ctcacaataa
    24901 actattatac tagaaaaaat ttttttacgc aagtaaaaac actagaattc gaaaaaacgc
    24961 cacatgggcg ttttcctgtt cttatggttt gatacggtgc aacatacgtg ggaatggaat
    25021 agcttcacgg atatgttttg ttcctgctgc gaaggttacc atacgttcga taccgatacc
    25081 aaatcctccg tgtggaactg taccgtattt acgaaggtca aggtagaatt catattctgt
    25141 acgatccatg ccaagttcat ccatcttagc gacaagggca tcgtaatctt cctcacgcat
    25201 agacccaccg ataatttctc catagccttc tggagcaagc aagtctgcac aaagcacgcg
    25261 ctctggattt ccaggaactg gtttcatgta gaaggccttg atggctgctg gatagttcat
    25321 gacaaatgtt ggcacaccaa agtggtttga aatccaagtt tcgtgtggtg acccaaagtc
    25381 atcaccatgc tcaagatgct cgtagtcagc atcttcatca ttttcatgct cttgcaagag
    25441 gtcaatggct tgatcgtaag tgatacgttt gaatggctct gcaatgtagc gtttcaagag
    25501 ttctgtatca cgttccaagg tttccaaggc ttgaggcgcg cggtcaagaa caccttgtag
    25561 aagagctttc acataagctt cttgcaagtc aagcgactca tcatgtgtca agtatgagta
    25621 ctcagcatcc atcatccaga actcagtcaa gtgacggcgt gtttttgatt tttcagcacg
    25681 gaaaactgga ccaaagtcaa agacacgacc aagagccata gcccctgctt ctaggtaaag
    25741 ctgacctgat tggctcaagt aggctggcgt tccgaagtag tcagtttcaa agagttctgt
    25801 agaatcttct gccgcatttc ctgaaagaat tgggctgtca aacttcataa aaccgttctt
    25861 gtcaaagaac tcataagttg catagataat agcgttacgg atttgcaaca cagctacttg
    25921 cttacgagag cgtagccaca agtgacggtt atccatcaaa aagtctgttc cgtgttcttt
    25981 tggtgtgatt gggtagtctt gagattcacc gatcacttcg atgtctgtga tgtccaactc
    26041 atagccaaat ttagaacgtt cgtcctcttt gacaatacct gtcacataaa cagacgtttc
    26101 ttggctcaag cgtttgataa catcaaactt ctcaagtccc acttcttcac caaatttttc
    26161 gacaaagttt ggtttaaaag ccacaccttg aaagaaggct gttccatcac gcaattgtaa
    26221 gaaagcgatt tttccttttc ctgatttgtt ggcaacccaa gcgccaatcg tcacttcctg
    26281 accaacatag tcttttacgt caataatcgt tacacgtttt gtcattattt ttccttttct
    26341 tttttattct ttatggcaaa ccacctctat attgttccca tccaggtcaa tcataaaagc
    26401 agcatagtaa atcagacgct cacttcgata accaggagcc ccattgtctc gcccacctgc
    26461 ctctaagcca gcctcataac aagcctgaac ttcttcctta ttttctgcta aaaaagcaaa
    26521 atgaacagga tcttgtgttc cctgagtcag ccaaaaatca ccaccaggat gagggctgtt
    26581 cggggataga aaactaatta gagaactagt cttaaaagcc aatttatagt ccaaaggagc
    26641 gagaaaactc ctataaaatc cttctgaaat ttgtaaatcc tttaccttaa tctcaaaatg
    26701 atcaatcatt ctcactaccc ataaatgctt tcaagcgttc gactgcttct ttaagcgtgt
    26761 ctaggtctgt cgcatagctg aggcggacat tttctggtgc tccaaatcca gctcctgtta
    26821 ccaaggccac ttcggcttct tctaagatag cagttgtaaa gtctgtcaca tccgtgtagc
    26881 ctttcatctc catggccttt ttgacatttg ggaagagata gaaggcccct tgcggtttga
    26941 ccacttcaaa tcctggcact tctgcaagga ggggatagat ggtattaaga cgttcctcaa
    27001 aggcctgacg catgctttct acagtatctt gctcacctga tagagcctca actgctgcat
    27061 attgggctac tgctgacgga ttcgaagttg tttgacctgc aatcttggac atggcagcga
    27121 taatgtctgc ttctccaacg gcataaccaa tccgccaacc agtcatggca taggttttag
    27181 acacaccatt gatgaccact gtttgcttgc gaatcgcttc cgataggcta gaaatcggtg
    27241 tgaactcatg accattataa accaagcggc catagatatc gtctgctagg atgagaatat
    27301 cattttctac agcccagttt ccaattgcca agagttcctc acgggtgtaa atcatacctg
    27361 tgggattaga tggcgaattc agcaccaaaa ccttggtctt gtcagtgcga gctgcttcta
    27421 actgctctac ggtcacctta aagtgattgt cttccttagc agaaacaaag acgggaacgc
    27481 cttctgccat cttgacctga tctccatagc taacccagta tggggttggg atgatgactt
    27541 catcacctgg attgaccaca gccataaaga aggtatagag agaatatttg gctcccgcag
    27601 cgactgtcac ttgatttgat gctacagaat agccgtaaaa gcgctcaaag tagctattga
    27661 ccgcctcctt aagctctggc agacctgagg ttactgtata aaaagaagca cgcccatctc
    27721 gaatcgatgc aatggcggca tcttggatat ttttgggagt agtgaaatct ggctcaccca
    27781 aggttagaga caaaatatct ctactctcag ccttcagtgc tttggcacgg gctccagcag
    27841 ccaaagtcac actttcttcc atttctaaaa cacggttgga tagtttcata ggccctcctt
    27901 gttgaccaat gctcctgttt caaaatctac tagataaaaa tcagatcctg acttaacttc
    27961 ccagattggc ttatcttgat aacggccaaa ggttatcttg tcaatctcgc cagctccctt
    28021 ttccttagaa accgtttctg ctttttcttg tgaaacaccc tgatttagct gataaacgta
    28081 aatcttatgg tcatctttac caatcaggac agcaagcgct tcttgctgtt tattacgacc
    28141 aagaacgctg taataagatt ccaagccatt gtataaatca acctgatcag cctgctctaa
    28201 tcctgcatac tgctgagcta atttttctcc ttcactttta gctgtttgat agggtttcat
    28261 gctaagagaa accatataca gaaaggaagc actgataacc acaaacaaaa tcgtcatccc
    28321 tagaccatac tgccacagta gattattttt tgctttgttt tgtctttttt tcactcgtct
    28381 attttaccat ctattaagct ttattacaag tgaatataag aatactcttc gaaaatctct
    28441 tcaaaccacg tcagctttat ctgcaacctc aaagctgtgc tttgagcaac caattctatt
    28501 tctcccttca aacaaaaccg attttgaaag tgaaacagtt cttacttttt cagtcacaaa
    28561 tgactagagt ttccgaaatt ttacaatttt caaataaact ctgagcaaat ttcttgcaag
    28621 ttcttttgtt ttgttgtaat atgttttata acaacgagag agttctcgaa attttaagaa
    28681 aaaggagaca catcatgtct aaaaaagtat tatttatcgt cggatcacta cgtcaaggtt
    28741 ctttcaacca ccaaatggcg ctcgaagctg agaaagcact tgctggtaaa gcggaagtta
    28801 gctaccttga ttattcagcc cttcctctct tcagccaaga tttggaagtt ccaacacatc
    28861 cagctgtagc tgctgctcgt gaagcagttc tcgttgcgga tgctatctgg attttctctc
    28921 cagtctacaa cttctctatc cctggtacag taaaaaactt gcttgactgg ctatctcgtg
    28981 cccttgactt gtctgataca cgtggcgctt ctgcccttca agacaagttt gtcacagtat
    29041 catctgtagc caatgcaggg cacgatcaac ttttcgctat ctacaaagac ctcttgccat
    29101 ttatccgtac acaaggcgtt ggtgatttca ctgctgcacg tgttaatgac tctgcctggg
    29161 cagacggaaa attggttctt gaagaaacag tcctaaactc acttgaaaaa caagctcaag
    29221 acttggtcga agctatcaag taactaacac tcaataaaaa tcaaaaagca aactaggaag
    29281 ctagccgcaa gctgctcaaa gcactgcttt gaggttgtag atagaactga cgaagtcagt
    29341 gacatatata cggtaaggcg acgctgacgt ggcttgaaga gattttcgaa gagtataaca
    29401 taataaaagc gaacaagact acttttctga cactcagaag actagtttgt tcgctttttt
    29461 tctcatttat aaactaaaac agctgatgat acatattgcc aaatacaaaa tatctgattt
    29521 ctatacttcc tttacaaaaa ccaatccctg tggttgtgac aaatcttctc ggtaaacaaa
    29581 tccagcaaag ttcaagcgac gtgcttcccc cacagtttgt acttgatttt ctattaaagc
    29641 tgttagaaag gccccgcgcg ctttcttgga gatagttgag tgaatcttca gctgaccgcc
    29701 tctatcctcc atgaatttga aggtcaccat ctttgctctg atttccttag aaaatacagt
    29761 ctcaaactct gatgacaaga gagagaaaat cacttcttcc ttcttcagag cttcatcata
    29821 gactgccttc caatggctct tcaaagtctt accagcgact tttaatttca tcaaaaaatc
    29881 caaacggtga ggagccatgg gtgacaaggc tggaacaaca ccgtacaaag ccgaggtaat
    29941 gaagacatga ttttcaagat aatcttgttc cgcctcggtc agcttatctc tcttaatgtt
    30001 gcggtacata agcccatcaa aaagtttcaa ggctggatag tgttgagcag tttgcctttt
    30061 caaagcttgg atattttgaa attcttccgc cgctttctca gccgatacct tgtagaaact
    30121 ctccaattga ctggcagaat agagagccaa ggcatcaagc acggtctgac tttctggttt
    30181 taaaggaatt gcctcgatac ttggcaagtc tgtgttcatt tcttttgctg ttgggattaa
    30241 aattttcata ttgatagtgt agcatatttt ttagccacaa ccaagaaatt catttgaaaa
    30301 acctcggttt gaccgaggtt tttctattta tttgggccat cctaaccaga cagccacgag
    30361 aacaagggct gtgccagcta aacttgttaa gatagataag aatttatctt ttttctcctt
    30421 gaactgagaa aaacctatct tcaaagcgag cagtccgagt agcattgaag caaccatcaa
    30481 ataaaaaccc atttctttgt cctccattag gcttaattca ccttattata acatatattt
    30541 attaaataaa ccttttttat actcaatgaa aatcaaagag caaactagga aactagccgc
    30601 aggctgctca aaacactgtt ttgaggttgc agatagagct agagattttc gaagagtatt
    30661 attgtacttt aaaggtcttg agataattgt cttttcctac ttgaccttcg aaggttttac
    30721 cattttcaag gtaaggaagg tcatcggata ctgaagcctt gaccttgtat atcttgccat
    30781 caactttaaa gaagtagaca gtgtctccct tgataacagc tgatttgagg tctgctacta
    30841 ctcccttgat gctttctgtc gttgcattgt caatttcaag gtcgttttta ttggcatact
    30901 tgctgagcat ctcttccact gtagtagcaa cgataacatt ttggtactcg actgcgtcta
    30961 ccagggcgta ctctttgacc aagccagcat tgtcctttaa gcccatgatg tagagaggct
    31021 tgtcattgag gttgatgagg attgggaagg ttgctttgta ggatttctcc tgaacagcac
    31081 cttctgctga ttcacgggct gattcttctg tcgcagaagc caagctatac ttagtgattt
    31141 ctcctgttcg catattttca aggatgaaac caagattact ctcatccgca ttagccgacg
    31201 tcacacctgt gtagagatag atgtcattac cgatagacaa gtaattatag cccttggtag
    31261 tctgggtcac atttttcttg gaaatcatgg cattcaagaa accgtccttg tacttgccgt
    31321 tgtagttgat ttgctcaatg gtttcctctg ctggatagac cctgtccacc cattctggaa
    31381 catctgataa gctgtattcc ttggtttctc catttgtagc atccaagata atgactgaag
    31441 caggacgagg aaccgcaagt ccaaattgct tttggtaaac cgttgctaca tagaaaggat
    31501 tgccctcatc gtccacctca aaagatggag ttttaaagat tttagtcggg tacttcaagc
    31561 gcaggtgacg tttgacatca cggttaaaat actccgagtc tgaatacttg attggtgtct
    31621 tcaagtccac caaatccgca tttccagtta ccatgtccac cttgatatac tcaccgattc
    31681 ccttggcttg attgttaaac catttgatag ggtctgcata ttctagtggt gtgacccgat
    31741 aaggtttccc atcaattgtc aattgggtat aggtatctgc cgctacgtat tgcgacacct
    31801 tatcggttag ggaacccaag tagcggtctc caattttttc agcagtactt ctatctagga
    31861 taggaacctt actggtgtca ctcttaggaa attcagtaaa gtctttttcc gtaaccgtga
    31921 ctacattggc ataattttta gcctgaaaca tgctggaagt taccaaggaa accaaagctg
    31981 ccaagagaag aattcctcca atcgaagcta acagaatttt ccctaaccga ttgattttga
    32041 aaccctcaag atttaaggca gcttccgcct taccgtggcg cacatgaacc gttttgacaa
    32101 ggtttatccc cttgccaaag ccaaataaga ttgccacaac taacaaatgc ccacagagga
    32161 agaagagaaa ttcccagctg gtcaggttaa ggggcggtaa aaagatatac caggtcgttg
    32221 cgataaaaat aagttcaaag actattcgtt tcatttgctt tcctcctaaa tgattcgtcc
    32281 ttccaagtga tccagctcat gctggcaaat ctgagctggg aagcctgtca aggtaatggt
    32341 ctgttcctgc cacttgctgt cacgataggc aagccttatg gtttcataac gcttagttga
    32401 tctcacacct accaaggaca aacagccttc ttctgcctca taagatcctt caaaggacag
    32461 aagcactggg ttaaacatga ccacgggaac caagccaaga ttaaagataa tcacgcgctt
    32521 ctgcacccca atcatattgg cagctagacc aacacaggta tcacgatttg ctaagagtgt
    32581 atcctgcaaa tctctggcaa gataaaggtc ctcctgactt gccggctgag acacttgaga
    32641 taaaaataag atatccttca caattttctt ttccacttcc tcacactcct cttgcttttt
    32701 actatattat agcaattata gcacaaaagc cgataactgc aaaccctttc cctcaactgt
    32761 agcaaaaagc catccgaaga tgactttttt gctatttaat ttctgtataa gttacttcca
    32821 atccacgctt aacagctgga cgattggcaa ttttttctgc ccattttact agattttgat
    32881 aacttgaggc atccaaaaat tttgcagaac cttggtaaag atttccttga actaactgtc
    32941 cataccaaga ccagatagca atatctgcaa tcgtatagtc attgcctgca atataaggtt
    33001 tctgagccaa ttccttatcc aataaatcca actggcgttt cacttccatc gtaaaacggt
    33061 taataggata ttccaatttt tcaggagcat aattgaagaa atgtccaaat cccccaccta
    33121 gaaaaggtgc tgcacctgct tgccagaata gccaattcaa aacttctacc ttttccacag
    33181 gattacttgg taaaaaggct ccaaatttct cagcaaggta aagaagaata tgagcagact
    33241 caaagactct tacgttttca gtacctgact ggtccaataa ggctggaatc ttggaatttg
    33301 gattgagctt cacaaagtct gagccgaatt gatccccatc catgatagca atcttataca
    33361 agtcgtaagc cgcttcctta aaaccagctt ctagtaattc ttccaataag atagtaacct
    33421 tcacaccatt tggtgttccc agtgaataaa gctgaaaagc ttgttctcct tttggcaagt
    33481 tttgttcgaa acgggcacct gctgttggtc tgtttagccc cgtaaaagct ccttgattac
    33541 tagcttcatc ctgccatacg gtcggtaatt gatatgctga catccgaaac ctcccttaaa
    33601 tcgcattctt gtcaaaaccg agtttgcgtt gaataaactt aacgatttcg acgatgataa
    33661 tcattaagaa gcttccagcc ataacaattc cccattgtga caagtctagt ttggttacgt
    33721 ggaagattcc ttcaagcggt tctacaacga ttgttgccat gagaaggata aaggatacca
    33781 agatggacca gttaaaggtc ttagacttga atgggccaac tgtcaagatg gattggtaga
    33841 cagacttgac attgtaggca tggaagagct gaatcaaacc aagggttgca aaggccatcg
    33901 ttagggcatc tgcatgaata gcatgattgt cacccacatg aactgggtaa gcaatcgcaa
    33961 ggccataaac actcataaca agagctgctt ggagtacacc ttgataaatg atagaactca
    34021 aaacaccacc tgagaagaag cttgccttgc gtccacgtgg tttatgattc atgacaccag
    34081 gttccgcagg ttcaacacca agagcgatag ctgggaaggt atccgttacc aagttgatcc
    34141 acaaaagatg aaccggctgc aagacatccc aaccaaacaa ggttgatagg aagatggtta
    34201 atacttcagc agtattagca gaaagtaggt actgaatagt cttttgaatg tttgagaaga
    34261 ccttacgtcc ttcttccact gcgacgataa tagtcgcaaa gttatcatct gcaagaatca
    34321 tgtcagaagc ccccttagaa acctctgtac cagtgattcc cataccgata ccgatatcgg
    34381 ctgttttcag agctggcgcg tcattgacac cgtcacctgt catggcaacg actttacctt
    34441 gtttttgcca agccttgacg atacgaacct tgtgttctgg agacacacgg gcataaacag
    34501 agtattgacc aacgactttt tcaaattctt catctgacag ttcattgagt tcagcaccag
    34561 ttaaaacgtg accttctgta tcgtttgcgt caatgattcc caaacgtttg gcaatggctt
    34621 ccgctgtgtc ttggtggtca cctgtaatca taattggacg gattcccgct tccttagcca
    34681 cacgaacagc ctcagcggct tcaggacgtt cagggtcaat catcccaatc aaaccagtaa
    34741 aaattaaatc attttcaagc tcttcagaag tgagattttc tggaatacta tcgataatct
    34801 tataagcacc tgcaaggaca cgcaaggctt gatgagccat ttcagaattg tttgtatgaa
    34861 tgagatttgt aaccttctca tcaatcggag caatatcccc agccttatca cgaagaagac
    34921 aacgttttaa gagttggtct ggcgcaccct tgactgctac aaggaaacga ccatctggca
    34981 atgggtgaac tgttgacatg agcttacggt cagagtcaaa tggcaattca gctacacgag
    35041 gatatttctc taagaaacct ttgacatcat agcccttgtc caaggcatat tggataaagg
    35101 ctgtttcggt tgggtcacca atcaagttac cttccacatc gattttcgta tcattggcca
    35161 agacaactga acgaagtagt ggcatttcaa gacctagttc aatatcatca gctgagtcat
    35221 gtagaaccgc atcgtagaag actttttcga ctgtcatctt gttcatagtc agcgtaccag
    35281 tcttatcaga agcgatgatt tcagttgaac caagtgtttc aactgctggc aacttacgaa
    35341 cgatggaatg tcgtttggcc aaaacttgag taccaagaga aagaacgatg gtaacgatag
    35401 caggaagtcc ttctggaatg gctgcaacgg caagggcaac agaagtcaac aactcaccaa
    35461 gtggattttt cccttgaatg aagacaccca ctacaaaagt aacaagggca atgaccaaga
    35521 tagcataggt caagacctta gaaaggttgt tcaagttttg tttgagtggt gtatcagtct
    35581 catccgcatc ttgaagcata ccagcaatat gaccaacttc agtatacata cctgtattga
    35641 caacaacacc catcccacga ccataggtta cgtttgagtt ttggaaggcc atgttgacac
    35701 ggtcaccaat accagcatct gtcgcaagct cgactgacaa gtctttttcg actggtacag
    35761 attcacctgt caaggctgct tcttcaattt taagagagtt ggcttctagc aaacgtaggt
    35821 ccgctggtac cacgtcacct gcttcaaggg caacgatatc gcctggtacc aattctttag
    35881 agtcaatctc tgccatgtgt ccatcacgaa gaacgcgggc aactggacta gacatggatt
    35941 tgagggcttc aatagcttct tcagcttttc cttcttggta aacaccaaag gcagcgttga
    36001 tgataaccac agctaggatg ataatggcat ctgcgatatc ttccccacca gaagtcacga
    36061 ctgacaagat tgctgccgca actaggatga taatcatcaa atccttaaat tgctcgatga
    36121 atttgaccaa gattgatcgt ttctcgcctt cttcgagttc attgtgccca aattcggcaa
    36181 ggcgcttttc cgcctcactt gatgacaaac cttgctcggt cgcatccata gcctgcaaga
    36241 cctcttcagg gctctgagta taaaacgctt ggcgtttttg ttcttttgac atgtgtctcc
    36301 tccttgacat tgtgtgcaaa acagactctc tttctgtcat atcttttcac gacaaacaaa
    36361 aagagacctg ttaatcataa caagtctcgc tgtttaagat agggccggaa agcatacttt
    36421 tcagcataaa attcggaatg acgacactat cacaggtttc tgccagctac tcccttgagt
    36481 agtaccatta taccaaattt tggggagttt tcaaagagta aaaactgcct tatttgaatt
    36541 tttccttgaa aaccagtata atggtagaat gctatgtgac tagaaaggaa gttgaatgaa
    36601 gcaatctatc tcaaatctca agttagctga gcgtggagcc attatcagta tttcgaccta
    36661 tttgatcttg tctgcagcca aattagcagc tggtcatctc cttcattcat ccagtttggt
    36721 ggccgatggt tttaataacg tatcggacat cattggaaat gtggccctct taatcgggat
    36781 tcggatggcg cgccagcctg cagaccgtga ccaccgtttt ggtcattgga agattgaaga
    36841 tttggcaagc ttgatcactt ctatcatcat gttctatgtc ggtttcgatg ttctaagaga
    36901 taccattcaa aagattctca gtcgggaaga aacggtcatt gatcctcttg gtgcaactct
    36961 aggaatcatt tctgcagcga ttatgtttgt ggtctatctc tacaatactc gcctcagtaa
    37021 gaaatccaac tccaaggcgc tgaaggcagc tgctaaggac aatctttctg acgctgttac
    37081 ctcacttgga accgccattg ccatcctagc tagtagtttc aattatccga ttgtggataa
    37141 actggttgct atcatcatca ctttctttat cttgaagact gcctatgata tcttcatcga
    37201 gtcttccttt agtctttcag atggctttga cgaccgcctg ctcgaggact accaaaaggc
    37261 tatcatggaa attcccaaaa tcagcaaggt caaatcgcaa agaggtcgca cctacggtag
    37321 caacatctac ctggatatta cactagagat gaatcctgac ttgtctgttt ttgaaagcca
    37381 tgaaatcgcg gatcaggtcg agtctatgct ggagaatcgt tttggcgtct ttgataccga
    37441 tgtccatatc gaaccagcac ctatccctga ggatgaaatt ttagacaatg tctataaaaa
    37501 attgcttatg cgtgaacaat tgatcgacca aggaaaccaa ctagaagaac tcttgactga
    37561 tgattttgtc tatattcgcc aagatggaga gcagatggat aaagaggctt ataagaccaa
    37621 aaaagagtta aattctgcta tcaaggacat tcaaattact tccatcagtc aaaaaaccaa
    37681 acttatctgc tatgagttag atggtatcat ccataccagt atctggcgtc gccacgaaac
    37741 ctggcaaaat atctttcatc aagaaaccaa aaaagaatag agaaatcctt tcatgagacg
    37801 ggatttttct attcttttat actcaataaa aatcggctct ataatatttg tagtgggtaa
    37861 atccactata ga
//
LOCUS       DAVMAH010000016        37183 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVMAH010000016 DAVMAH010000000
VERSION     DAVMAH010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37183
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.016"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(98..2356)
                     /locus_tag="VYO94_000749"
     CDS             complement(98..2356)
                     /locus_tag="VYO94_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1759414.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGATREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VYO94_000750"
     CDS             complement(2585..2815)
                     /locus_tag="VYO94_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV1759415.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VYO94_000751"
     CDS             3005..3688
                     /locus_tag="VYO94_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1759416.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VYO94_000752"
     CDS             3688..4422
                     /locus_tag="VYO94_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1759417.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLRKVL"
     gene            4576..5433
                     /locus_tag="VYO94_000753"
     CDS             4576..5433
                     /locus_tag="VYO94_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV1759418.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETGLVPGLVVILVGDNP
                     ASQVYVRNKERSALGAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VYO94_000754"
     CDS             5575..6447
                     /locus_tag="VYO94_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV1759419.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VYO94_000755"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VYO94_000755"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV1759420.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTSKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKIVATPSKEYIWVVDESKLVDKLGAFKLPVEVVQYGAEQIFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIEDPIVFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QILTSRKEK"
     gene            7426..8637
                     /locus_tag="VYO94_000756"
     CDS             7426..8637
                     /locus_tag="VYO94_000756"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV1759421.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFAPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGVIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VYO94_000757"
     CDS             8639..9181
                     /locus_tag="VYO94_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV1759422.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9197..10006
                     /locus_tag="VYO94_000758"
     CDS             9197..10006
                     /locus_tag="VYO94_000758"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1759423.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10482..10877
                     /locus_tag="VYO94_000759"
     CDS             10482..10877
                     /locus_tag="VYO94_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEV1759424.1"
                     /translation="MLDSKEELKESENDASKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            10887..11462
                     /locus_tag="VYO94_000760"
     CDS             10887..11462
                     /locus_tag="VYO94_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1759425.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPRSSSQPSAEPME
                     NIALGKQVTQSSTVFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            11487..11909
                     /locus_tag="VYO94_000761"
     CDS             11487..11909
                     /locus_tag="VYO94_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV1759426.1"
                     /translation="MSAQITINHKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIY"
     gene            12653..13363
                     /gene="deoD"
                     /locus_tag="VYO94_000762"
     CDS             12653..13363
                     /gene="deoD"
                     /locus_tag="VYO94_000762"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1759427.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13386..13910)
                     /locus_tag="VYO94_000763"
     CDS             complement(13386..13910)
                     /locus_tag="VYO94_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV1759428.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     HEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13963..14199)
                     /locus_tag="VYO94_000764"
     CDS             complement(13963..14199)
                     /locus_tag="VYO94_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV1759429.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14267..15187)
                     /locus_tag="VYO94_000765"
     CDS             complement(14267..15187)
                     /locus_tag="VYO94_000765"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV1759430.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15385..15789
                     /locus_tag="VYO94_000766"
     CDS             15385..15789
                     /locus_tag="VYO94_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759431.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16005..16586
                     /locus_tag="VYO94_000767"
     CDS             16005..16586
                     /locus_tag="VYO94_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1759432.1"
                     /translation="MYYAENPDAAHDIYELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16583..17860
                     /locus_tag="VYO94_000768"
     CDS             16583..17860
                     /locus_tag="VYO94_000768"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV1759433.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17878..18540
                     /gene="deoC"
                     /locus_tag="VYO94_000769"
     CDS             17878..18540
                     /gene="deoC"
                     /locus_tag="VYO94_000769"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV1759434.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18527..18916
                     /locus_tag="VYO94_000770"
     CDS             18527..18916
                     /locus_tag="VYO94_000770"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1759435.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19007..20059
                     /locus_tag="VYO94_000771"
     CDS             19007..20059
                     /locus_tag="VYO94_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV1759436.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20203..21738
                     /locus_tag="VYO94_000772"
     CDS             20203..21738
                     /locus_tag="VYO94_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759437.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21731..22789
                     /locus_tag="VYO94_000773"
     CDS             21731..22789
                     /locus_tag="VYO94_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1759438.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLTELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAVNSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22792..23748
                     /locus_tag="VYO94_000774"
     CDS             22792..23748
                     /locus_tag="VYO94_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1759439.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            23833..25170
                     /locus_tag="VYO94_000775"
                     /pseudo
     CDS             23833..25170
                     /locus_tag="VYO94_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(25213..25854)
                     /gene="plsY"
                     /locus_tag="VYO94_000776"
     CDS             complement(25213..25854)
                     /gene="plsY"
                     /locus_tag="VYO94_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV1759440.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDFLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            25990..27933
                     /gene="parE"
                     /locus_tag="VYO94_000777"
     CDS             25990..27933
                     /gene="parE"
                     /locus_tag="VYO94_000777"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV1759441.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTNE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEETTVF"
     gene            28353..30824
                     /gene="parC"
                     /locus_tag="VYO94_000778"
     CDS             28353..30824
                     /gene="parC"
                     /locus_tag="VYO94_000778"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV1759442.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVIIEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEYK"
     gene            30956..31978
                     /locus_tag="VYO94_000779"
     CDS             30956..31978
                     /locus_tag="VYO94_000779"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV1759443.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            32034..32738
                     /locus_tag="VYO94_000780"
     CDS             32034..32738
                     /locus_tag="VYO94_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1759444.1"
                     /translation="MVLSTLAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLRP
                     TASSGGSPIVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            32803..33492
                     /locus_tag="VYO94_000781"
     CDS             32803..33492
                     /locus_tag="VYO94_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV1759445.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            33489..34412
                     /locus_tag="VYO94_000782"
     CDS             33489..34412
                     /locus_tag="VYO94_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV1759446.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            34427..35071
                     /gene="pcp"
                     /locus_tag="VYO94_000783"
     CDS             34427..35071
                     /gene="pcp"
                     /locus_tag="VYO94_000783"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1759447.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            35239..35469
                     /locus_tag="VYO94_000784"
     CDS             35239..35469
                     /locus_tag="VYO94_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV1759448.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            35519..35599
                     /locus_tag="VYO94_000785"
     tRNA            35519..35599
                     /locus_tag="VYO94_000785"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35553..35555,aa:Tyr,seq:gta)
     gene            35609..35680
                     /locus_tag="VYO94_000786"
     tRNA            35609..35680
                     /locus_tag="VYO94_000786"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35641..35643,aa:Gln,seq:ttg)
     gene            35842..37044
                     /gene="rpsA"
                     /locus_tag="VYO94_000787"
     CDS             35842..37044
                     /gene="rpsA"
                     /locus_tag="VYO94_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV1759449.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSIKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRVARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT        11142 a         6637 c         8417 g        10987 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag tagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagta tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttgaccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatctgtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt cgtccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatatc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttggtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgactta tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt aaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcaat caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccgc ttttatttgc
     3601 agcattttat tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggcatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag cttatctttg agggagtcga tattacggac
     3901 aagaagaatg acctgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gattgaaaat attaccttgt cacctataaa gaccaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc agcaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgaga aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa caggtctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg gggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaagaa tgctacagtg actttgaccc attcacgcac ccataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa ccgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttattgta taataaaagt gagaggaaaa aaggatgaaa
     5581 gtgattaatc aaaccttatt agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagccta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagttg tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagag
     6421 agggtaagta aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaaaga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt gaaaagaaaa tacatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactg ggaacgggtt ctactgccta ttattttgtc gaagaaattg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacgacttct agtgtgacca
     6901 gtaaacaggc tgaagggctt aacattccac tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacagt cgacggagcg gatgaagtag atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctgatggag aagattgttg caacgccctc aaaagaatac atttgggtag
     7081 tggatgaaag caagctggta gacaaactag gtgcttttaa attgcctgtg gaagtggttc
     7141 aatatggtgc agaacagatt tttcgtcgtt ttgagcgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga tggccaacgt tttgtgaccg atatgcagaa ctttatcatt gaccttgcct
     7261 tggatgtcat cgaagatcca attgtttttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tagaacacgg tttattcaac caaatggtgg acaaggtcat tgttgctgga cgagatgggg
     7381 ttcagatttt aacctcaaga aaagaaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcact tggtggtatt ggattctgta ggaattggtg ctgcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggtgcc tctgacacac tgggacacat ttccaaaacc
     7561 gttggtttga atgtcccaaa catggctaaa atcggtcttg gaaatattcc tcgcgaaacg
     7621 cctttgaaga ctgtagcagc tgaaagcaat ccaacaggat atgcgacgaa attggaagaa
     7681 gtatcccttg gtaaggatac catgactggt cactgggaaa tcatgggact caacattacg
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aatcgaagaa
     7801 ttttcaggac gtaaggtcat tcgtgaagcc aacaaacctt actcaggaac agctgttatt
     7861 gatgactttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttac aaattgctgc ccacgaagac atcattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat cactcttgag cgccctgccc ttctaggtcg tatcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacag ccaaccgtcg tgacttagcc
     8101 gtttctccat ttgcaccgac tgttttggat aaattgaatg aagctggtat cgatacttac
     8161 gctgttggta aaatcaacga tatctttaac ggtgctggta ttaaccatga catgggtcac
     8221 aacaagtcaa acagccatgg aattgataca ctattgaaga ccatgggtct tgctgagttt
     8281 gaaaaaggat tctcattcac aaacttggtg gactttgatg ccctttacgg ccaccgtcgt
     8341 aatgctcatg gttatcgtga ttgcttgcat gagtttgatg aacgcttgcc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accacgggaa cgacccaact
     8461 tacgcaggaa cagaccacac tcgagaatat atcccacttt tggcttacag tcctgctttt
     8521 aaaggaaatg gtgtcattcc agtaggacat tttgcagata tttcagcgac tgttgctgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt ggtaagaata aggtcgtcat
     8701 ggcggagctt cgtcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 cagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagatttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctggg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca gaagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt ggatcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caaggtcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcaga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     9721 caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aaggggtagt gcctctgtct tttcaggatt gactgcctat ccgtattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtatgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagctttcta
    10201 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataataa ataatgaaaa ttggtcaacg aattatgcgc tttggtataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgcttcaa aactagaaac tcctcttaga gaggagccaa
    10561 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtaga gataacagag ccagctcaag cggatgatat ccgcaaggtt gttggggaat
    10681 tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt ggaggctacc
    10741 tagctcagat tgcagcggtt gaagattacc aaaaatatcc tgatttttat aaccatgtat
    10801 tgaggaaagt gacaactttc agtgctccta aagtcattac ttccagaact gtttgggatg
    10861 ctaagaatgg tttctgagat gttggtttgg aaagtcgtaa attagctgtt agtggaaaaa
    10921 ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat aataatcgtg
    10981 atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc tattttgaaa
    11041 gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg gataaacatg
    11101 gttatcgtga tccgaaattg gataaagtgc gattctttaa gaaacaggct ctgcctcgat
    11161 cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa caggttactc
    11221 aaagttcgac agttttcgga ggagatgcta gaagagctgt ggatggcaaa gtcgatggta
    11281 actatggtca caattctgtc actcatacaa acttccaatc taagccttgg tggcaagtag
    11341 atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca gacactgccc
    11401 aggatagatt ggcaaacttt gatgtcattc ttttagacag ttctggtaaa gaaattgagt
    11461 gaaaacgtat aacatctcct aaagatgtgt cagcacaaat tacgattaac cataaaaaag
    11521 tgcgctatgt tcggattgag ctagaaggct ataatgccct cagtcttgca gaagttgaag
    11581 ttttccgctt tatagctacg aatgctgaaa cggcgacaca agtttctaag ccagttcaac
    11641 caatcagtca gactcctgtg aaagataaaa cattgacaat tcaacacagt ggagcttaca
    11701 ttgcccgcta ctccataact tgggaagaag ttccagtaga taaagatgga aaccaagttg
    11761 ttcgtagtca ttcttgggaa ggaaacggtt gcaaccagac tgcaggtttt gtcctcaacc
    11821 tcccaatcaa agaaaatatg agaaatctgc gagttaagat tgagaaaaag acgggcctac
    11881 tatggaatag atggcaaaca atctattaaa acagaccaat tttagctcaa ctccaccgta
    11941 aaattaccca ttggggtacg acattgaatt ccaaggtgag tgacgatgat gtcttgtaat
    12001 ctgatggtac aatgacagtt agtttgtcta gtttataaga aagtactacc tgagcttgaa
    12061 tagaactcag gtagctctct gtgaaagaac aaaattaata ctcaatgaaa atcaaagagc
    12121 aaactaagaa actagccgca ggttgctcaa agcactgctt tgaggttgta gataagactg
    12181 acgaagtcag tcacatatat aatccaaggc gacgttgacg tggtttgaag agattttcga
    12241 agagtataaa cagaaaggta gagcgcgtgt tctaatttga acacgagtag aaaacttttc
    12301 taaaaacaaa aacgaaagga tgggtaaact gtattcgctg aactgaatac gggcgactct
    12361 cctctaaatc aaaattaaga aaggaattga ccccacccta aaagtagtgg gaaaaagata
    12421 gttgatctag cgagcatcgc tcactgcgcc caactcctat tttcccttcg ctttttgatg
    12481 ggtttggtat ctttctcaat ataaaatata aaataaagaa aggtagagcg tgtgttttga
    12541 tttgaacacg agcggaaaac tcggaaaata gataatctga ctgaaaaatc aggatttctc
    12601 gtcaggttcc taattttcag tcgttttctt ctcgctcttt gtatcataaa ttatgtctat
    12661 ccatattgct gctcagcagg gtgaaattgc tgataaaatt cttcttcctg gggatcctct
    12721 tcgtgctaag tttattgcgg agaatttcct tgatgatgct gtttgtttta acgaagtgcg
    12781 taacatgttt ggttacactg gtacttacaa gggtcactgt gtatctgtca tgggaactgg
    12841 gatgggaatg ccatctattt cgatttatgc gcgtgagtta atcgtagact acggtgtgaa
    12901 gaaattgatt cgtgtgggaa ctgcaggttc tttgaatgaa gaggttcatg ttcgtgaatt
    12961 agttttggcg caggcggctg caaccaactc aaacatcgtt cgtaatgact ggccacagta
    13021 cgattttcca caaattgcta gctttgattt gcttgataaa gcctaccata tcgccaaaga
    13081 acttggtatg actactcacg ttgggaacgt tttgtcatct gatgtctttt actcaaatta
    13141 ctttgaaaag aatatcgagc ttggtaaatg gggagtcaag gctgtggaaa tggaagcagc
    13201 agctctttac tatcttgctg cccaatacca tgttgatgcg ctagctatca tgaccatctc
    13261 tgatagcttg gtcaatccag acgaagacac aactgcagaa gaacgtcaaa ataccttcac
    13321 tgatatgatg aaggttggtt tggaaacctt gattgcagaa taattatagc caaaaaggaa
    13381 gccctttatg aattgtagga cttccttttc ttatccagaa attgatctag ctctctctga
    13441 tttcgaagaa tagtgacttt atgtgaatat tcttggcaaa gtttttggta attttctttt
    13501 tgagttttgc tacgcccatc ccaaagaatc catctgataa actcccactc aaagcgttca
    13561 gggcaatctg ccgccatact ttctctgact tttccacggt atttaagata acgcttaaag
    13621 gctctaaaga gacaggtcaa tggcgaaaaa ttgagaaaga tgatttggtc agcttcttgc
    13681 attcgttctt ggtagtagca ccaagaataa ttaccatcga tgacccaagc tttatgcttg
    13741 gtgagaaagt tttttatctc ggttaacatc cattcgtggt cactgtcttg ccaaccaggt
    13801 tgaaattgga gtgtgtccat gtgcagtttt ggaatggagt agtagttaga taacttttct
    13861 gctagagttg acttaccaga accagaatat ccgataattg cgattttcat tttctacctt
    13921 ttcccatttg gagacaaaaa aacagcctct atggactgtt tcttatttag caagtttagc
    13981 tgaaagacga gctttatcgc ggcttgcttt gtttttgtga atcaaacctt tagtttctgc
    14041 tttatcgata gctgagctag cagcacggaa aagttcttca gatgggtttg cttcgaaagc
    14101 ttttatagca gtacgcatag ctgatttttg agctgagttc ttttcgtttt gtttaacgtt
    14161 caattcagcg cgtttgatag ctgatttaat gtttgccaat gttcttacct ccatatttac
    14221 taactatacc attatatatg aaaacttacg ttttgacaag ggaaaattac ttttttaagt
    14281 aaatttcatc gatttcatgg ttcttgcttt tatgaagaat cacttctgca cgatttctgg
    14341 ttggttcaat ataattttgc agatttgtga gattgatact gatccagacc tgatgggcaa
    14401 aggcttccac ttccccaatc ggcatctgag taaaacgata atagtagcta tcagggtcgt
    14461 tttgggctag gctcagcatt ttcaagaaac ggtccagata ccaactttca atatcatcca
    14521 ctccagcatc tacatagatg gaaaagtcaa agaagtcagt gatatagaga cgatcgtttt
    14581 gtggattttg aaagacattg attccctcaa caattacaaa atcagcagct ttgacacttt
    14641 gtttctcttc gggtacgatg tcgtaaactt catgagaata gacaggaata tctacatctt
    14701 gtccattttt gatgcggtcc aagaagttga gaagagcttc catatcatag ctttcaggaa
    14761 atcctttacg atttaaaatc ccctgctcaa tcaaggtttg attgggatag agaaaaccat
    14821 cagttgtaac caactcaacc gtagcatctg taaacgtacg ggacagtagg atttgaagta
    14881 ggcgactggt tgtggatttt ccaacggcaa cactcccaga aaccccaata ataaaaggtt
    14941 gagatttact ttcacgttgg aggaaaattc cttttgaaaa ggctaaatct tccttagttc
    15001 gcttgtaaat ctgaatcaga tgagctaagg ggagatagat atctgtaacg tcttggagac
    15061 tgatttggtc attaaaactc ttgatagatt ccaattcttc ttctgtcaaa ggaggtgttg
    15121 tctttcgatg taaagattgc caagtctggc ggctgatttt ttcaaaatgt aaaaattcgt
    15181 tggtcatttg ttttccccta gatattttgt ctatcatacc ataaaaagct aaaaaaataa
    15241 agcggtttct tgaatgtggt aagtcaatgg tatatagtat aagtgatcaa tttattgatg
    15301 aaataggaga tagattctac tgatttataa gtttataagc ttataaaggg ggctttttag
    15361 ttcacaactt ataggaggtg tactatgaaa atcttaaaac gttacatatt ggaactctgt
    15421 tttattttaa gttttgcttt accttttata aaaggagcca atgcagataa tggtatatgc
    15481 tttgtggaaa cctattacgg ttttactttt ttgatggaac atgctattgt aacagctgtc
    15541 tttatctatt cgtttttaat tgctttctta ctaaaaaaac gatgggcgaa atggattgct
    15601 gctggtagtt attgcttttt agtcctatgg attgcgacag agggttattt cttccgcatg
    15661 tcactagaag atttgatacg actttggaca agtttggaaa tcctgacaca aacgtatcag
    15721 ttgggctttt atctaaacat tttgttggga attttgttga taataaagta ttttaaggtt
    15781 aagcaataga aataataatc tgcctgatta tagatgataa actttttgtt tttatctgga
    15841 ctgtgatatt tatagttcta aatggtttat tatttataag tgttgaaaga gattgaagaa
    15901 aatggcttcg tgactcgctt tcttcggtct ttttcgtttt attatcaatt tgtaaacgat
    15961 ttacaatttg agtcaaatta tggtaaaata gtgtcatgag taaaatgtat tatgcagaaa
    16021 atcctgacgc tgctcacgac atttatgagt tgagagtaga gttgttggga caaaaaatga
    16081 cctttttaac ggatgcgggt gtttttagca agaaaatagt tgactttgga agtcaactat
    16141 tgctcaagtg tcttgaggtc aaccaaggag aaactgtcct tgatgtaggc tgtggttacg
    16201 gacctttggg tttgtcctta gctaaggctt atggagttca ggctactatg gttgatatca
    16261 acactcgtgc cttagattta gctcggagaa atgctgaaaa aaataatgca aaagcgacga
    16321 ttttccagtc caacatctat gaacaagttg aaggacattt tgatcatgtc atttccaatc
    16381 ctcctatccg tgcgggcaag caagttgttc atgaaatcat tgagaaaagt aaagattttt
    16441 tggaaactgg tggggatttg acaatcgtca tccagaaaaa acaaggggct ccaagtgcta
    16501 agtccaagat ggaggatgtg tttggtaatt gtgaaatcct taaaaaagac aaaggatact
    16561 atatccttag aagtgtgaaa gaatgagagc agttgattta atccaaaaaa aacgagacgg
    16621 tcaagaactg acttcaagtg aaattgaatg gctgatagaa ggctatgtat caggaactgt
    16681 tcctgattat cagatgtctg cctttgctat ggctgtttat tttaaaggaa tgacgactcg
    16741 agaaatctct gatttaacga tgaatatggt taagactggg caagagtttg acctgtcagc
    16801 cattgatggt gtgaaagttg acaagcattc tactggtggt gtcggcgata aggtaacctt
    16861 gattttagct cctcttgttg ctagcttcgg tgtgcctgta gcaaaaatga gtggtcgtgg
    16921 tcttggccat acaggcggaa caattgataa attggagtcc attaagggct atcaagtaga
    16981 acgtagtcaa gaggatttta ttcgtcaggt tcaggatatt ggagtatctg tcattgggca
    17041 atcagaccag ctggtcaaag cagataagct tctctatgcc cttcgtgatg tgaccgcaac
    17101 tgtcgacacg attcctttga ttgcgagttc ggtgatgagc aagaaaattg cggcaggggc
    17161 ggatgctatt ttgctagacg tgactgtcgg tgagggtgcc ttcatgaaga cggttgatga
    17221 ggcgcgtgag ttggctcaaa ctatggtaga tcttggtaag gttgttggac ggaagacagt
    17281 agcagtgatt acggatatga gccagccttt gggacgagcg attggaaatc gtctggaaat
    17341 ccttgaagca ttggagattt tgcaaggtca aggacgtcag gatattaccc actttatttg
    17401 tgaattggct caaattatgc ttggtttggc aaatgttaac aaaactgttg aagaagttcg
    17461 ccaacatctt gagaatggtc aagcactggc taagtttgag gaaatggtgc aagcccaagg
    17521 tggagacttg gaagacctct atcgtcctgt aaatgtagct catgtggtgg aaatccctgc
    17581 tcaggaaacg ggtgtcattt cagctcttcc agctatggac tttggtcttt atgccatgag
    17641 gctgggtgct ggtcgtgcag ttaagtctga tgccttggac tatgaaacag gaattgtttt
    17701 tgaaaagaag attggagact ccgttcaaaa gggtgaaatt gttgcaaaag tatacacaaa
    17761 tgaaaaaatt ccacctcaac tagttacaga tttccaaaaa tgtgttaaaa taagtgatga
    17821 agtgaaaaaa atccgtgaaa ttgtagaaat catctcctaa atggagggaa aaccgaaatg
    17881 aaattaaata aatatataga tcatacgctt ttaaaacaag atgcaaagaa aaaacaaatt
    17941 gatagtttgt tgtctgaggc tagagagtat ggctttgcca gtgtttgcgt taatccaacc
    18001 tgggttgaac atgctaaaaa agggcttgaa ggcacagatg ttaaggtttg cacggtagta
    18061 ggtttccctt tgggagcaac aacttcagcc gtgaaagcat ttgagacaaa agaagctatc
    18121 caaaatggtg cagatgagat tgatatggtg atcaatgttg gagctctcaa atcaggtaat
    18181 ttagccttgg ttgagtcaga tattcgcgca gtagtggaag caagtggtga taagttagtg
    18241 aaagtcatta ttgaagcttg ccttctgaca gaccaagaaa aagttgttgt ttgccaattg
    18301 gcccaaaaag ctggggctga ctttgtcaaa acatctactg gcttttcaac tggtggtgct
    18361 acgatagcag atgttacatt aatgcgtgaa acagttggat ctgatatggg agtcaaggct
    18421 gctggtggag ctcgttctta tgcagatgct cttgcctttg tcgaagcagg tgcgacccgt
    18481 atcggaacgt cagctggggt agctatttta aaaggagaat tggcagatgg cgactactga
    18541 gttgattgaa ctggcaattg aaaccagcaa acatgcctat gtcccctatt ctcactttcc
    18601 tatcggagca gttttagtag ccaaagacgg aaatgtttac acgggagtga atatcgaaaa
    18661 tgctagctat cctttgacca attgcggtga gagaacagct atttttaagg ctatatctga
    18721 aggccaaaga gaattttcag aattgattgt ctatggtcaa actgaaaaac cgatttcacc
    18781 atgtggtgct tgtcgccaag taatggtcga attttttgaa caagatttaa aagtgacctt
    18841 agtcgcaaaa gataaatcga cggtcgagat gacggtcggg gagttacttc catattcttt
    18901 tacagactta aattagtctg agtcgctctt tgagtggcaa gggtctttgt gaccaatcaa
    18961 tccatacttg caacatcgtt gcacatctta tttaggaggt tcagtaatga acaagaaaca
    19021 atggctaggt cttggcctag ttgcagtggc agcagttgga cttgctgcat gtggtaaccg
    19081 ctcttctcgt aacgcagctt catcttctga tgtgaagaca aaagcagcaa tcgtcactga
    19141 tactggtggt gttgatgaca aatcattcaa ccaatcagct tgggaaggtt tgcaggcttg
    19201 gggtaaagaa cacaatcttt caaaagataa cggtttcact tacttccaat caacaagtga
    19261 agctgactac gctaacaact tgcaacaagc ggctggaagt tacaacctaa tctttggtgt
    19321 tggttttgcc cttcacaatg cagttgaaga agcagctaaa gaacacactg acttgaacta
    19381 tgtcttgatt gatgatgtga ttaaagacca aaagaatgtt gcgagcgtaa ctttcgctga
    19441 taatgagtca ggttaccttg caggtgtggc tgcagcaaaa acaactaaga caaaacaagt
    19501 tggttttgta ggtggtatcg aatctgaagt tatctctcgt tttgaagcag gattcaaggc
    19561 tggtgttgcg tcagtagacc catctatcaa agtccaagtt gactacgctg gttcatttgg
    19621 tgatgcggct aaaggtaaaa caattgcagc cgcacaatac gcagccggtg cagatattgt
    19681 ttaccaagta gctggtggta caggtgcagg tgtctttgca gaggcaaaat ctctcaacga
    19741 aagccgtcct gaaaatgaaa aagtttgggt tatcggtgtt gaccgtgacc aagaagcaga
    19801 aggtaaatac acttctaaag atggcaaaga atcaaacttt gttcttgtat ctactttgaa
    19861 acaagttggt acaactgtaa aagatatttc taacaaggca gaaaaaggag aattccctgg
    19921 cggtcaagtg atcgtttact cattgaagga taaaggggtt gacttggcag taacaaacct
    19981 ttcagaagaa ggtaaaaaag ctgtcgaaga tgcaaaagct aaaatccttg atggaagcgt
    20041 aaaagttcct gaaaaataat ggatggaagt catttcttag gaagcggcca agggccgctt
    20101 ttttaagagt tgagacaaag tcattttgtc tcagtaaagc ttgctactag acaaactagc
    20161 aagttttatt gaaataaaat aagactctga aaggaagagc acatggcaca cgaaaatgtc
    20221 attgagatgc gtgatattac caaggtgttt ggtggatttg ttgctaacga caaaatcaac
    20281 ttgcacctac gaaaaggtga aattcatgca cttttaggag aaaatggggc tggtaagtcc
    20341 acgctaatga acatgttagc aggccttctt gaaccaacta gtggtgaaat cgcggtcaac
    20401 ggtcaagttg tcaatctcga ctccccatct aaagcagcta gcttgggaat cgggatggtt
    20461 caccagcact ttatgttggt tgaagccttc acagtggctg aaaacatcat tttaggtagt
    20521 gaattgacta aaaatggtgt gctagatatc gctggagcta gcaaagaaat caaggctctt
    20581 tctgaacgtt atggcttagc tgttgaccct tctgccaagg tagcagatat ctcagttgga
    20641 gcccaacaac gtgtagaaat tttaaaaaca ctttatcggg gggctgatat ccttatcttt
    20701 gacgaaccaa cggctgtttt gactccatca gaaattgatg agttgatggc tattatgaaa
    20761 aatcttgtca aagaaggaaa atcaattatc ttgattaccc acaaattgga tgaaattcga
    20821 gcagtttctg accgtgttac agttatccgt cgtgggaaat caattgaaac cgttgaaatt
    20881 gcaggggcta ccaatgctga tttggcggaa atgatggtag gacgttctgt ttcctttaaa
    20941 acagagaagc aagcctctaa accaaaagaa gtggttttgt ctatcaaaga tttggtggtc
    21001 aatgaaaacc gtggtgttcc agctgttaaa aatctgtcct tggatgttcg tgctggagag
    21061 attgttggta ttgcggggat tgatggaaat ggtcagtctg aactgattca agccattaca
    21121 ggtcttcgta aggttgaatc tggtagcatt gagctaaaag gagattcaat tgtaggcttg
    21181 cacccacgtc agattacaga actaagtgtt gggcacgttc cagaagaccg tcaccgtgat
    21241 ggcttgattt tggaaatgat gatatctgaa aatattgccc ttcaaaccta ctataaagaa
    21301 ccacatagta aaaatggaat tttgaactat tcaaatatta cttcttatgc taaaaagctg
    21361 atggaagagt ttgacgttcg cgctgccagt gaattagttc ctgcagctgc actctcagga
    21421 ggaaatcaac aaaaagcaat tattgctcgt gaaattgatc gagatcctga tctccttatc
    21481 gttagccagc caactcgtgg gttggatgtc ggtgccattg agtatatcca caaacgcttg
    21541 attgaagagc gtgataatgg caaggctgtc cttgttgtca gctttgaatt ggatgagatt
    21601 ttaaacgtct cagaccgtat tgccgttatc cacgatggta agattcaagg tattgtatca
    21661 ccagaaacaa ccaataaaca agaacttggt gtcttgatgg ctggtggaaa cttgggaaag
    21721 gagaagagtg atgtctaaaa aattacaaca aatttcggtt cctttgattt ctgtattcct
    21781 aggaatttta ctcggagcca ttgtcatgtg gatcttcggt tatgatgcta tttggggcta
    21841 cgaagaattg ttctatacag cctttggcag tctgcgtggg attggagaaa tcttccgtgc
    21901 tatgggtcct ctggtcttga ttggtcttgg ttttgcggtt gccagtcgag ctggtttctt
    21961 taacgtcgga cttcctggtc aggctttggc aggttggatt ctcagtggtt ggtttgccct
    22021 gtcgcatcca gatatgcccc gtcccttgat gattctagca accatcgtga ttgccttgat
    22081 tgctggtggg attgtcggag cgattccagg tattcttagg gcctatctag ggacgtcaga
    22141 ggttattgta accatcatga tgaactacat tgtcttgtat gtagggaatg cctttatcca
    22201 tgctttccct aaagacttca tgcaaagtac agattcgacc attcgtgttg gggctaatgc
    22261 aacctatcag acaccttggt tgactgagtt gactggtaac tcacggatga atattggtat
    22321 tttctttgcc atcattgccg ttgcagttat ttggttcatg ctcaagaaaa caactcttgg
    22381 ttttgaaatc cgtgcagttg gtcttaatcc acatgcttca gaatatgctg gtatttctgc
    22441 caagcggact attatcctat ctatgattat ttcaggtgcc ttggcaggtc ttggtggagc
    22501 tgttgaaggt ttgggaacct tccagaacgt ctatgttcaa ggttcgtcat tagctatcgg
    22561 atttaacgga atggcggtta gtttgcttgc ggtcaactca ccaattggta tactctttgc
    22621 agccttccta tttggcgttc tccaagttgg ggctcctggt atgaatgcgg cgcaggtacc
    22681 atctgagctt gtcagcattg taacagcgtc tattatcttc tttgtcagtg ttcattacct
    22741 tatagaacgc tttgtcaaac cgaaaaaaca agttaaagga ggtaagtaaa gatgtctatt
    22801 ataaccttgc tccccctctt ggtgtcttct atgctgattt actcagcacc tctcatcttt
    22861 acaagtatcg gtggtgtttt ctctgaacgt ggtggtgtgg taaacgttgg ccttgaagga
    22921 attatggtta tgggtgcctt ttctggagtt gtctttaacc ttgaatttgc agaacaattt
    22981 ggagcagcaa ctccatggct atccttgctt gtagcaggat tggttggtag tgttttctct
    23041 atcatccacg cagcagcgac ggttcatttc cgtgcagacc atgttgtcag cggtacggta
    23101 ttgaacttga tggcgcctgc cttggctgtt ttcttagtta aagttcttta taacaaagga
    23161 caaaccgaca acctaagtca aacttttgga cgctttgatt tcccagtctt ggcaaatatc
    23221 ccagtgattg gtgatatctt cttcaagtca actagtctac ttggttatct ggcgattgcc
    23281 ttctcattcc ttgcttggtt tattctcttt aagactcaat ttggtcttcg tctccgctct
    23341 gtcggtgaac atcctcaagc agcggatacc ttgggaatca acgtctacaa gatgagatat
    23401 ttaggggtta ttatttcagg ttttctaggt ggaattggcg gagcgattta tgcgcaatca
    23461 atctcagtta acttctcagt aacaactatt gttggacctg gatttatcgc ccttgctgcg
    23521 atgatctttg ggaaatggaa tccaatcggt gctatgcttt ctagtctctt ctttggactt
    23581 tcacaaagtt tggctgttat cggttctcaa ttgccgttcc tacaaggagt gccagcggtt
    23641 tatcttcaaa ttgcacctta tgttttgaca attcttgtct tagcagcctt ctttggaaaa
    23701 gcagtcgcac caaaagcaga tggtatcaac tacatcaaat caaaataagc atacaaaaaa
    23761 acgtcagtcc aatgactgaa ctgcacccca aaagttagac agaaaaaatc taacttttgg
    23821 ggtgttttta tcatgaagtt aacttatgat gataaagttc agatctatga acttagaaaa
    23881 caaggatata gcttagagaa gttttcaaat aaatttggga taaacaattc taatattagg
    23941 tacatgatta aattgattga tcgttacgga atagagttcg tcaaaaaagg aaaaaatcgt
    24001 tactattctc ctgatttaaa acaagaaatg attcataaag tctgacatga aggctggact
    24061 aaagatagag tttctcttga atacggtctc ccaagtcgta cgatacttct taactggcta
    24121 gcacaataca ggaaaaacgg gtatactatt gttgagaaaa caagagagag agtacctaaa
    24181 atgggacgta agccaaaaac gagacctgaa gagaggacag aattagaaca tcttcaagca
    24241 gaaaatgagt acctgagagc ggagaatgcc atcctaaaaa agttaagaga actccgattg
    24301 aaggaggaaa aagagaaaga agaaagacag aaattgttca agaattaatg actgagtttt
    24361 cgtcagatct tcttctaaaa gccattaaac tagctcgttc gacctactac tatcacttga
    24421 aacagctaga caaaccagat aaggaccaag agcttaaagc tgaaattcaa tccatcttta
    24481 tcgaacacaa gggaaattat gcttatcgcc ggatttattt agaactaaga aatcgtggtt
    24541 atctggtaaa tcataaaaga gttcaaggct tgatgaaagt actcaattta caagctaaaa
    24601 tgcgacagaa acgaaaataa aggagacgtt ggtaagaagg cagagaatct cattcaaggc
    24661 caatttgaag gctctaaaac aatggaaaag tgctacacag atgtgacaga atttgccatt
    24721 ccagcaagta ctcaaaagct ttacttatca ccagttttag atggctttaa tagcgaaatt
    24781 atcgcctata atctttcaac ttcacccaac ttagaacaag tacaaacaat gttggaacag
    24841 gcattcacag agaagcacta cgagaatacg attctccata gtgaccaagg ctggcaatat
    24901 caacacgatt cttatcatca gtttcttgag ggtaagggaa ttcaagcatc catgtcacgc
    24961 aagggaaaca gcccagacaa tggtatgatg gagtccttct ttgggattct gaaatcggaa
    25021 atgttttacg gttatgagaa gtcgtttcag tcgtttaagc aattggaaca agctattgta
    25081 gactatattg attactacaa caacaaacga attaaggtaa aactaaaagg acttagtcct
    25141 gtgcagtaca gaactaaatc ctttggataa attatttgtc taactgtttg ggggcagtac
    25201 agaactggcg ttttattttt taggatcttg atgggttagg ttcaatcccc aagggaccaa
    25261 attttcagtt ttatttttga tacgagctat attgtcctta tgacgaatga taatcaaact
    25321 agcaagtgct aagataatag cgatgaagag aaagtcatag ttactcagga taaaaccaaa
    25381 aagtggaaag agcagaaccc cgataacagc cgcaatcgat gctgtgacac tagacagtga
    25441 aatcatactg ccaagataga gagctccaaa gaagataatc gcaaggtaga gacagaagat
    25501 aggcgcaaat ccgaaaatca ctccagcact ggttgcgaca gccttaccac ctttaaatcc
    25561 tgcaaagata gggaaggtat ggccgataac agccaaaagt ccaaagatga gaggagaaac
    25621 gccttgtaga tgaaaaataa tcggaagcag cgttgctagg gttcctttga aaaagtcaat
    25681 cacaaaggtt gccataccag ctttcttacc taaaatgcgg aaggtgttgg tcgttccagt
    25741 gttaccagaa ccatgctcgc gtagattgat ttgaaagaat acttgtccaa tccagagacc
    25801 agatggaatc gaacccagca gataggctag gattaataaa actattgtaa tcatactcct
    25861 attatatcat gaattgggaa agaaaagcag agaatctctg ctgaaattgt cacatcggag
    25921 aaagaaaaat tttgcaaaat ccttggaaaa cctgtagaat agtaaagatg aacgaatagg
    25981 aggttccttg tgtcaaaaaa ggaaatcaat attaacaatt ataatgatga tgctattcag
    26041 gtgctagaag ggttggatgc ggtccgaaaa cgtccaggga tgtatattgg atcgaccgat
    26101 ggcgctggtc ttcatcacct agtttgggaa atcgttgata atgcagtcga tgaagccttg
    26161 tctgggtttg gtgatcgtat tgatgtaact atcaataaag acggtagtct aacggttcaa
    26221 gaccatggac gtgggatgcc gacaggtatg cacgctatgg gaattccaac tgttgaggtt
    26281 atctttacca ttcttcatgc cggagggaaa ttcggtcaag gtggctataa gacatcaggt
    26341 ggacttcacg gagtgggttc ttccgttgtt aacgcccttt ctagctggtt agaagttgaa
    26401 attacccgtg atggcgcagt ttacaagcaa cgtttcgaaa atggtggaaa acctgtcacg
    26461 actttgaaga aaatcggtac agcacccaag tctaaaacag gcaccaaagt tacttttatg
    26521 cctgacgcga ctatattttc tacgacagat ttcaagtaca ataccatttc agagcgcctt
    26581 aatgaatcag cctttctctt gaaaaatgtg accttgtctt taacggacaa gcgaacaaat
    26641 gaagcgattg agttccacta tgagaatgga gtacaagatt ttgtttctta tctcaacgaa
    26701 gataaggaaa tcttgacgcc agttctttac tttgaagggg aagacaatgg ttttcaagtg
    26761 gaagtagccc tccagtacaa tgacggattc tcagataaca ttctatcttt tgtcaataac
    26821 gttcgcacca aggacggtgg aacgcacgag acaggactca agtctgccat taccaaggtc
    26881 atgaatgact atgcacgtaa aacaggtctt ctcaaggaaa aagataaaaa ccttgaaggt
    26941 tcagactatc gtgagggact agcggccgtt ctttctatct tagttcctga agaacacttg
    27001 cagtttgaag gacagaccaa ggataaacta ggaagccccc tagctcgccc agttgtggat
    27061 ggaatagtgg ctgataagtt gacctttttc cttatggaaa atggggaatt agcttctaac
    27121 ctcatccgca aggctatcaa ggcccgtgat gctcgtgaag cagcacgtaa ggcgcgtgat
    27181 gagagccgaa atgggaagaa aaacaagaaa gataagggct tgttgtctgg gaaattgacc
    27241 ccagcccaat ctaagaatcc tgctaagaat gaactctatc tagttgaggg ggactctgcc
    27301 ggtggttctg ccaaacaagg tcgtgaccgc aagttccagg ctattctacc tcttcgtggt
    27361 aaggttgtca atacagccaa ggccaagatg gcggatatcc tcaaaaatga agagatcaat
    27421 accatgattt ataccattgg tgcgggtgtt ggagcagact tctctattga agatgccaac
    27481 tatgataaga tcattattat gaccgatgcg gataccgacg gtgcccatat ccagaccttg
    27541 ctcttgacat ttttctaccg ttacatgcgt ccgctagtcg aggcaggtca tgtctatatt
    27601 gccctcccac ctctttacaa gatgtccaaa ggtaaaggca agaaagaaga agtggcctac
    27661 gcttggacgg acggagaact agaagaactc cgtaaacagt tcggtaaagg cgctaccctc
    27721 caacgataca aaggacttgg tgagatgaat gcggaccagc tctgggaaac aaccatgaac
    27781 ccagaaacac gtaccctcat ccgtgtcaca attgaagatt tagcgcgcgc cgaacgccgc
    27841 gtcaatgttc tcatgggaga taaggtagaa ccacgccgta aatggattga agataatgtc
    27901 aagtttacgc tagaagaaac gacagtgttt taatgaaaga aaataatatg ttagtaaact
    27961 ggaaattaga gtcggatgtg aatgactatg tgaaaaagca gtttgaaaat cttggtttga
    28021 aaaaattgca ggattattaa tgaagaatct gctatgagtg cttatctcaa agaggcgctt
    28081 aagggagcgg ctaagacaca aactaagact aattttggaa aaccagattt tcatattgaa
    28141 aaatacaaac aggatagttt ggttacttat cgtaactgaa cacgggagga attcccgtaa
    28201 aatatctttt actgcataaa aacctactct acattctttg aaaggagttg aacacgccct
    28261 agatactgtg tgaaaaagat aaattctctt gtgagtttgc ttacttcaag aattttctat
    28321 tttcacttgg tattttatgg gctttgtatc ttatgtctaa cattcaaaac atgtccctgg
    28381 aggacatcat gggagagcgc tttggtcgct actccaagta cattattcaa gaccgggctt
    28441 tgccagatat tcgtgatggg ttgaagccgg ttcagcgccg tattctttat tctatgaata
    28501 aggatagcaa tacttttgac aagagctacc gtaagtcggc caagtcagtc gggaacatca
    28561 tggggaattt ccacccacac ggggattctt ctatctatga tgccatggtt cgtatgtcac
    28621 agaactggaa aaatcgtgag attctagttg aaatgcacgg taataacggt tctatggacg
    28681 gagatcctcc tgcggctatg cgttatactg aggcacgttt gtctgaaatt gcaggctacc
    28741 ttcttcagga tatcgagaaa aagacagttc cttttgcatg gaactttgac gatacggaga
    28801 aagaaccaac ggtcttgcca gcagcctttc caaacctctt ggtcaatggt tcgactggga
    28861 tttcggctgg ttatgccaca gacattcctc cccataattt agctgaggtc atagatgctg
    28921 cagtttacat gattgaccac ccaactgcaa agattgataa actcatggaa ttcttgcctg
    28981 gaccagactt ccctacaggg gctattattc agggtcgtga tgaaatcaag aaagcttatg
    29041 agactgggaa agggcgcgtg gttgttcgtt ccaagactga aattgaaaag ctaaaaggtg
    29101 gtaaggaaca aatcgttatt attgagattc cttatgaaat caataaggcc aatctagtca
    29161 agaaaatcga tgatgttcgt gttaataaca aggtagctgg gattgctgag gttcgtgatg
    29221 agtctgaccg tgatggtctt cgtatcgcta tcgaacttaa gaaagacgct aatactgagc
    29281 ttgttctcaa ctacttattt aagtacaccg acctacaaat caactacaac tttaatatgg
    29341 tggcgattga caatttcaca cctcgtcagg ttgggattgt tccaatcctg tctagctaca
    29401 tcgctcaccg tcgagaagtg attttggcgc gttcacgctt tgacaaagaa aaggctgaga
    29461 aacgtctcca tatcgtcgaa ggtttgattc gtgtgatttc gattttggat gaagtcattg
    29521 ctcttatccg tgcttctgag aataaggcgg acgccaagga aaacctcaaa gttagctatg
    29581 attttacgga agaacaggct gaggctatcg taactttgca actgtaccgt ttgaccaata
    29641 ccgatgtggt tgtcttgcag gaagaagaag cagagcttcg tgagaagatt gctatgctgg
    29701 cggctattat cggtgatgaa aggactatgt acaatctcat gaagaaagaa cttcgtgagg
    29761 tcaagaagaa atttgcaact cctcgtttga gttctttaga agacactgcg aaagcaattg
    29821 agattgatac agctagtctt atcgctgagg aagataccta cgtcagcgtg accaaggcag
    29881 gttacatcaa gcgtaccagt ccacgttcct ttgcggcttc caccttggaa gaaattggca
    29941 agcgtgatga tgaccgtttg atttttgttc aatctgccaa gacaacccag cacctcttga
    30001 tgttcacaag tcttggaaat gtcatctaca gaccaatcca tgagttggca gatattcgtt
    30061 ggaaggacat cggagagcat ctgagccaaa ccatcacaaa ctttgaaacg aatgaagaaa
    30121 tcctttatgt ggaagtactg gatcagtttg acgatgcgac aacctacttt gcagtgactc
    30181 gccttggtca aatcaaacgg gtagagcgaa aagaattcac tccatggcgg acctatagat
    30241 ctaagtctgt caagtatgct aagctcaaag acgatacaga tcagattgta gcagtggctc
    30301 cgattaaact agatgatgtt gtcttggtta gtcaaaatgg ttatgccctg cgtttcaata
    30361 tcgaagaggt tccggttgtc ggtgctaagg cagcaggtgt caaggctatg aatttgaaag
    30421 aagatgatgt cctccaatct ggctttatct gtaatacttc gtccttctac ctcttgaccc
    30481 agcgtggaag cttgaaacgt gtttctattg aggaaattct agcaaccagc cgtgccaaac
    30541 gaggattaca agtcttgcgt gagttgaaaa acaaaccgca tcgtgtcttc ttggcaggag
    30601 cagttgcaga gcaaggattt gttggcgatt tcttcagtac ggaagtggat gtgaacgacc
    30661 aaactctgct tgtccaatcc aataaaggaa caatctatga aagccgattg caagacttga
    30721 acttgtcaga acgcactagc aatggaagct tcatttctga cacgatttca gatgaagaag
    30781 tttttgacgc ttatcttcag gaagtagtta ctgaatataa ataagtgaaa tgaagaataa
    30841 gttctaagag ctggttttta ttggagaaat tttctgaaaa ttacaaaata tacttgctat
    30901 tttagaaaaa tagtgtagaa tataagaaat aggtttttag aataaggagt ggaatatgac
    30961 agtaacgatt gattgggaaa acctcggttt ttcctatatg aaattacctt atcgctatct
    31021 tgctcatttc aaaaatggac aatgggatca aggagagctt acagaggatg caactttgca
    31081 tatttcagag tcttctccaa gtcttcacta tggacaacaa gcatttgaag gtttgaaagc
    31141 ttatcgtact aaggatggca gtgttcaact gttccgtcct gatgaaaatg ctaaacgtct
    31201 gcaacgtaca tgtgaccgtc tcttgatgcc acaagttccg acagacatgt ttgtagaagc
    31261 ttgtaaagca gttgtccgtg cgaatgaaga atacgtacca ccatacggaa caggtggaac
    31321 cttatatctt cgccctcttt tgattggtgt cggagatatt atcggggtaa aaccggcaga
    31381 agagtacatt ttcaccatct ttgctatgcc agttggaaat tactttaaag gtggtttggt
    31441 cccaaccaac ttcttgattc aggatgagta cgaccgtgca gcaccaaatg gtacaggtgc
    31501 ggctaaggtt ggtggaaact atgctgcaag tctcttacca ggaaaaatgg ccaagtcacg
    31561 tcatttctca gatgttatct atctggaccc atcaactcat acaaagattg aagaagtcgg
    31621 atcagctaac ttctttggaa ttacagctga taatgaattt gtaacaccat tgagtccatc
    31681 tatcttgcca tctattacca agtattcctt gctttatttg gcagaacatc gcttgggatt
    31741 aactcctatt gagggtgatg ttccaattga taatcttgac cgttttgtag aggcaggtgc
    31801 ctgtggtaca gcagcggtta tttctccaat tggaggtatt caacatggtg atgatttcca
    31861 tgtattctat agtgaaacag aagtaggtcc tgtgacgcgt aaattatata atgaattgac
    31921 gggtattcag tttggcgata ttgaagcgcc agaaggttgg attgtaaaag tagattaaaa
    31981 taaaccaaag gagatttttt atgaaataga aaaagtggct cttaacagca ggagtggtcc
    32041 tgagcacgtt agctatttta gtggcttgtg gaaaaactga taaagaagca gatgcaccga
    32101 caacattttc ttatgtctat gcagtagatc cagcatcatt gggctacagt atagcgactc
    32161 gaacatcgac gacagacgtt attggaaatg ttattgatgg tttgatggaa aatgataaat
    32221 acggcaatgt tgctccttct caaaaagact atgatttgaa tagtacagga tgggctccaa
    32281 gctatcaaga tccagcgtct tacttgaata ttatggatcc aaaatctggt tctgccatga
    32341 aacaccttgg tattacgaaa ggaaaagata aggatgttgt agctaaacct ggtttggata
    32401 aatataagaa attgttagaa gatgctgttt ctgagaccac tgacctagag aagagatatg
    32461 aaaaatatgc caaagctcaa gcttggtcga cagatagttc attattgagg ccaacagctt
    32521 catctggtgg ttctccaatt gtaagtaacg tagtaccatt ctcaaaacca tactcacaag
    32581 ttggtattaa gggggaacca tatatcttta aaggaatgaa attgcaaaaa gatattgtta
    32641 caacaaaaga atataacgag gtttttaaaa aatggcaaaa agaaaaattg gaatccaata
    32701 gcaaatacca aaaagaacta gaaaaataca ttaaataagg aatggtattg atcttgataa
    32761 aatttttaaa atactgtcat tttgaatata aaggagtttg atatggagtg gattagatta
    32821 ataggaatag caatcattgt tgtgggtttt attttaaaat ttgatacaat tgcaacagta
    32881 gtcttagctg gtttggttac agctttagtt tcaggtgttt ctctcgttga atttttggag
    32941 attttgggaa aagaatttag caatcagcga gtgctcacga tttttatggt taccttgcct
    33001 cttgtggggc tgtcagaaac ctttggactc aagcaacgat caatcgattt gattcgaaag
    33061 attaaaggtc tgacagttgg aaacttctat acagtttatt tctttattcg agagttagct
    33121 ggtttctttt caattcgtct aggaggacac cctcagtttg tcagaccttt ggttcaacct
    33181 atgggagaag cagctgcaga gtctcaatta ggtagaaagt taacagaggt tgaagatgag
    33241 acaataaaag cgcgtgcggc agcgaatgaa aattttggaa atttctttgc tcaaaatacg
    33301 tttgtaggtg ctgggggagt cctcttgata gggggaacat tagatcagtt aggctatgaa
    33361 agcaattatg cagggattgc ttctacatct attattgttg ctgttataac acttattgta
    33421 gtggggattt acaattattt atttgataaa aaattgatat caaaaaagac taggggagga
    33481 gaacaaaaat gacagagttg gcaaagcaac tattagagtt gacctatatt gtgattggtt
    33541 gtcaatttct ccatacagcc tattgtagtt ataaagataa aacaaaccca gttcgacttg
    33601 ggacatctgc attttggact ctattgtcta ttacgtttat aggtggttcc tatatgccaa
    33661 atatgagtat tggtattatt gtaatcctat tatcgctgtt aacattgttt aagcaagtcc
    33721 gtatcggaac cttgccatcc ttagatgaaa tgaaagccaa tattgaatct aacaggttga
    33781 aaaataaaat ttttattcca gttatgctga tggcaatact tgcgttggtc ttagcgcaaa
    33841 tgattccaga atttagcaag atttcgatta gccttgccgc cttgtttgct acaatttctg
    33901 ttcttgtgat taccaatagt caccctaaga gtctgttatc agaaaataat cgaatgactc
    33961 agcaagtttc aacaagtggg attgttcctc aattattagg ggctttgggg gctattttta
    34021 ctgtagcagg tgttggtgat gttatctctc atctgatcag cggtattgtt ccttcagata
    34081 gtcgctttat aggagttttg gcctatgttc ttggaatggt tctattcaca atgattatgg
    34141 gaaatgcttt tgcagcattc accgttatta cagcaggtgt tggagttccc tttgtatttg
    34201 ctctgggagc taatccaatt gtggctggtg ctcttgccat gacagcaggt tattgtggga
    34261 ccttattgac cccaatggct gctaatttta acgctctacc agcagcattg atggatatga
    34321 aagatcagaa tggcgttata aaggctcaag caggtgttgc tctagtaatg attgttattc
    34381 acatattctt aatgtacttt ctcgcatttt agtaaaggaa aataaaatga aaatattggt
    34441 tacaggtttt aatccttttg gaggtgaaaa gattaatcca gctttggagg ctgtaaaatt
    34501 attaccatct gagattaatg gggctgaagt tcgctgggta gaaattccaa cggtttttta
    34561 taagtcgtca gaagttttag aggcagaaat attacgatat caaccagatg ctgtactttg
    34621 tattggacaa gcaggcggca ggaccggctt aacacctgaa cgagtggcta ttaatcaaga
    34681 tgatgctcgc atacctgata acgaaggcaa tcaaccaatt gatacaccga ttcgtattga
    34741 tggagcatcg gcctatttta gtagtttacc tatcaaagcg atggtacaag ctatcaaaaa
    34801 acagggactt ccggcagttg tatccaatag tgcaggaacc tttgtttgca atcatttgat
    34861 gtaccaagct ctttatttag tggataaaaa attccctaat atgagagcag gtttcatgca
    34921 tattccatat atgatggaac aagtagtaaa taagccgaat actgcaggaa tgagtctatg
    34981 tgatattgta agaggcatag aggtagctat tgaagctatt gtagactaca aagataagga
    35041 tttgcagtta gtaggcggtg agactcactg ataacctaaa aaggatagtc aattatgctt
    35101 gtttactaac tattagctat gctaaatcga ttgaggttgt ttacataaaa ctctatatca
    35161 gagaagcctg atatagagtt ttttcttgct agttttagga ttttcttgta aaatagaaaa
    35221 agtgaagaga ggtatgaaat gagcaagaaa gataaaaaaa tcgaaattca agtagcggat
    35281 gccaaagtta atgttggtaa agacagtttt gaaggttata cattgactat cggtaaaaaa
    35341 gttatcggag aaattgccga attagacgga caatttgcca ttataaagaa tgggaatgtc
    35401 gatagttttt ataaaaaatt ggaaaaagct gtggaaattt tgattgaaaa ttataattta
    35461 gcaaaataag tcttgttttt ttgaaatttt catgatataa tagtccatgt tgattgtagg
    35521 agagatagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg gttcgggggt
    35581 tcgaatccct ctctctccat ttcattaatg gggtatagcc aagcggtaag gcaagggact
    35641 ttgactccct catgcgttgg ttcgaatcca gctaccccag ttcttaggta ataatcaaga
    35701 taaaaagcaa aatatcttag ggtattttat ttttataatt gaaagacgtg aatgatatga
    35761 acatgtcctt gcgggtgctt aggaaaaaaa ttataagtat gtcaagttta agaaaaactt
    35821 gattgttgga ggatttttta gatgaacgaa tttgaagatt tgctaaatag cgttagtcaa
    35881 gttgagactg gtgatgttgt tagtgctgaa gtattgacag ttgatgcgac tcaagctaac
    35941 gttgcaatct ctggaactgg tgttgaaggt gtcttgactc ttcgcgaatt gacaaacgat
    36001 cgtgatgcag atatcaatga ctttgttaaa gtaggagaag tattggatgt tcttgtactt
    36061 cgtcaagtag ttggtaaaga tactgataca gttacatacc ttgtatctaa aaaacgcctt
    36121 gaagctcgca aagcatggga caaacttgtt ggtcgcgaag aagaagttgt tactgttaaa
    36181 ggaacgcgtg ccgttaaagg tggactttca gtagaatttg aaggtgttcg tggatttatc
    36241 ccagcttcga tgttggatac tcgtttcgta cgtaacgctg agcgttttgt aggtcaagaa
    36301 tttgatacta aaatcaaaga agttaacgct aaagaaaacc gcttcatcct ttcacgtcgt
    36361 gaagttgttg aagcagctac tgcagcagct cgcgctgaag tattcggtaa attggctgtt
    36421 ggtgatgttg taactggtaa agttgctcgt atcacaagct tcggcgcttt catcgacctt
    36481 ggtggtgttg atggattggt tcacttgact gaattgtcac atgaacgtaa cgtatcacca
    36541 aaatcagttg taactgttgg tgaagaaatt gaagtgaaaa tccttgatct taacgaagaa
    36601 gaaggacgtg tatcactttc tattaaagca acagtaccag gaccatggga tggcgttgag
    36661 caaaaattgg ctaaaggtga tgtagtagaa ggaacagtta aacgtttgac tgacttcggt
    36721 gcatttgttg aagtattgcc aggtatcgat ggacttgttc acgtatcaca aatttcacac
    36781 aaacggattg aaaatccaaa agaagctctt aaagttggtc aagaagttca agttaaagtt
    36841 cttgaagtta acgcagatgc agaacgcgtg tcactttcta ttaaagctct tgaagaacgt
    36901 ccagcccaag aagaaggaca aaaagaagaa aaacgtgttg ctcgtccacg tcgtccaaga
    36961 cgtcaagaaa agcgtgattt cgaacttcca gaaacacaaa caggattttc aatggctgat
    37021 ttgtttggtg atatcgaact ttaatcaaat tgaaaattca caaaatcctt tgtttactaa
    37081 acaaaggatt tttctggctc tttgtcaact gtagtgggtt gaaaaaaagc taagctcgag
    37141 aaaggacaaa tttcgtcctt tcttttttga tattcagagc gat
//
LOCUS       DAVMAH010000017        36335 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVMAH010000017 DAVMAH010000000
VERSION     DAVMAH010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36335
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.017"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(237..1871)
                     /locus_tag="VYO94_000788"
     CDS             complement(237..1871)
                     /locus_tag="VYO94_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759450.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLFMFINIAFRFPFEEMPSFFSTMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALAGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVTLVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(1852..2601)
                     /locus_tag="VYO94_000789"
     CDS             complement(1852..2601)
                     /locus_tag="VYO94_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759451.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            2780..4234
                     /locus_tag="VYO94_000790"
     CDS             2780..4234
                     /locus_tag="VYO94_000790"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV1759452.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKTQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYNW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4324..6942)
                     /gene="alaS"
                     /locus_tag="VYO94_000791"
     CDS             complement(4324..6942)
                     /gene="alaS"
                     /locus_tag="VYO94_000791"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV1759453.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGRRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(6964..7449)
                     /locus_tag="VYO94_000792"
     CDS             complement(6964..7449)
                     /locus_tag="VYO94_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV1759454.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(7724..7963)
                     /locus_tag="VYO94_000793"
     CDS             complement(7724..7963)
                     /locus_tag="VYO94_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759455.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8224..9294)
                     /locus_tag="VYO94_000794"
     CDS             complement(8224..9294)
                     /locus_tag="VYO94_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1759456.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYEAFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKLEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9291..10064)
                     /locus_tag="VYO94_000795"
     CDS             complement(9291..10064)
                     /locus_tag="VYO94_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1759457.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(10061..10867)
                     /locus_tag="VYO94_000796"
     CDS             complement(10061..10867)
                     /locus_tag="VYO94_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1759458.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10848..12005)
                     /locus_tag="VYO94_000797"
     CDS             complement(10848..12005)
                     /locus_tag="VYO94_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759459.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(12165..13070)
                     /gene="murB"
                     /locus_tag="VYO94_000798"
     CDS             complement(12165..13070)
                     /gene="murB"
                     /locus_tag="VYO94_000798"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV1759460.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(13182..13934)
                     /locus_tag="VYO94_000799"
     CDS             complement(13182..13934)
                     /locus_tag="VYO94_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV1759461.1"
                     /translation="MTIHIIITMLLLLTFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(13944..14675)
                     /gene="budA"
                     /locus_tag="VYO94_000800"
     CDS             complement(13944..14675)
                     /gene="budA"
                     /locus_tag="VYO94_000800"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV1759462.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            14817..16088
                     /locus_tag="VYO94_000801"
     CDS             14817..16088
                     /locus_tag="VYO94_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV1759463.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(16108..16923)
                     /locus_tag="VYO94_000802"
     CDS             complement(16108..16923)
                     /locus_tag="VYO94_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1759464.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(17080..17733)
                     /gene="phoU"
                     /locus_tag="VYO94_000803"
     CDS             complement(17080..17733)
                     /gene="phoU"
                     /locus_tag="VYO94_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1759465.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(17745..18503)
                     /gene="pstB"
                     /locus_tag="VYO94_000804"
     CDS             complement(17745..18503)
                     /gene="pstB"
                     /locus_tag="VYO94_000804"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1759466.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(18516..19319)
                     /gene="pstB"
                     /locus_tag="VYO94_000805"
     CDS             complement(18516..19319)
                     /gene="pstB"
                     /locus_tag="VYO94_000805"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1759467.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(19330..20214)
                     /gene="pstA"
                     /locus_tag="VYO94_000806"
     CDS             complement(19330..20214)
                     /gene="pstA"
                     /locus_tag="VYO94_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1759468.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(20204..21121)
                     /gene="pstC"
                     /locus_tag="VYO94_000807"
     CDS             complement(20204..21121)
                     /gene="pstC"
                     /locus_tag="VYO94_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1759469.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(21121..21999)
                     /gene="pstS"
                     /locus_tag="VYO94_000808"
     CDS             complement(21121..21999)
                     /gene="pstS"
                     /locus_tag="VYO94_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV1759470.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(22573..23877)
                     /locus_tag="VYO94_000809"
     CDS             complement(22573..23877)
                     /locus_tag="VYO94_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV1759471.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCAGLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLFPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(23878..24651)
                     /locus_tag="VYO94_000810"
     CDS             complement(23878..24651)
                     /locus_tag="VYO94_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV1759472.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLAYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(24641..24919)
                     /locus_tag="VYO94_000811"
     CDS             complement(24641..24919)
                     /locus_tag="VYO94_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV1759473.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGKGKISLGK"
     gene            complement(24919..25320)
                     /locus_tag="VYO94_000812"
     CDS             complement(24919..25320)
                     /locus_tag="VYO94_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV1759474.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(25530..26147)
                     /locus_tag="VYO94_000813"
     CDS             complement(25530..26147)
                     /locus_tag="VYO94_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV1759475.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKNFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(26137..26910)
                     /locus_tag="VYO94_000814"
     CDS             complement(26137..26910)
                     /locus_tag="VYO94_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV1759476.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRGIPYLFVTNN
                     TTRTLESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(26921..27658)
                     /locus_tag="VYO94_000815"
     CDS             complement(26921..27658)
                     /locus_tag="VYO94_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV1759477.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSVVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(27663..28793)
                     /locus_tag="VYO94_000816"
     CDS             complement(27663..28793)
                     /locus_tag="VYO94_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV1759478.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIVVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(28877..29266)
                     /locus_tag="VYO94_000817"
     CDS             complement(28877..29266)
                     /locus_tag="VYO94_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1759479.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(29282..29665)
                     /locus_tag="VYO94_000818"
     CDS             complement(29282..29665)
                     /locus_tag="VYO94_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV1759480.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(29666..30454)
                     /locus_tag="VYO94_000819"
     CDS             complement(29666..30454)
                     /locus_tag="VYO94_000819"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV1759481.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGFRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(30447..31382)
                     /locus_tag="VYO94_000820"
     CDS             complement(30447..31382)
                     /locus_tag="VYO94_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV1759482.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(31512..31688)
                     /locus_tag="VYO94_000821"
     CDS             complement(31512..31688)
                     /locus_tag="VYO94_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV1759483.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(31768..32268)
                     /locus_tag="VYO94_000822"
     CDS             complement(31768..32268)
                     /locus_tag="VYO94_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759484.1"
                     /translation="MNKEDFLKIKEAYKSVRLEEKNRIKDFLLSKRDSDGNLIFFKEK
                     DGTDTFVRTGRGYGNKHYSSGGTLSRPYDLSNHMWIDLSYKGNDILISLQSFDIDPNN
                     EKNLHVLYDRIGIMFEKDGKILLPDNKSEVSDAFLKMETTNWELPLSEADMEEMVNYI
                     INHYEE"
     gene            complement(32346..33053)
                     /locus_tag="VYO94_000823"
     CDS             complement(32346..33053)
                     /locus_tag="VYO94_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV1759485.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FTKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            33204..34232
                     /gene="queA"
                     /locus_tag="VYO94_000824"
     CDS             33204..34232
                     /gene="queA"
                     /locus_tag="VYO94_000824"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV1759486.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRIIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(34893..35282)
                     /locus_tag="VYO94_000825"
     CDS             complement(34893..35282)
                     /locus_tag="VYO94_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1759487.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(35336..36028)
                     /locus_tag="VYO94_000826"
     CDS             complement(35336..36028)
                     /locus_tag="VYO94_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1759488.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTRTRTYDVNPETGHVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDGPTLDKSQEVEEVG
                     EIGKLLLLQSIL"
BASE COUNT        10867 a         8270 c         6815 g        10383 t
ORIGIN      
        1 atatgttcta tcaaaaatac ttgaaaaaga cacattatag gaattaacgt ttttgaaatt
       61 gaaaaatatc caaataaata aactataaac aacaaaaata gaactatatt atatttctta
      121 ttcaaaacat tcctccctat atttttgatt accaatctta atcatttaca actacattct
      181 aacaaactat aaaagcgttt gtcgaattga atttatcaag caagcaacca actatctcat
      241 cttttttcta tttctgccaa tatgcgtgac aggtaataat gatagccaaa aatagcaaga
      301 gcaagcaaga cgataagagc tcctactccc aagttgatgg caaggatagg ggagagagac
      361 tgaaccaaga atatgctccc aattacaagg gccatcagga ttgcactata aataaacaat
      421 aaaactatgg cgactatgcc atttgaacga ttcaccaggt ccgtaatgct actccaattg
      481 gttgacagat ttttaacgtc cttaaagtaa tggtggcaag aaaggatgac actggcaatg
      541 atccagacta caagaaggta aatcatcgaa aggatggaca agcctagata tagagaaaga
      601 ccgagcaaag tcagaactgg taaaaaggac tgaacagcaa agataatcca aaatttcact
      661 ttcacataac gagcaaagtc aaagggtaaa ctcttcagaa aatcaacatt ttccctctcc
      721 aaggacaagg caattgaatg caggctggtg atattgttat tgacaactgc tataaacact
      781 cctacaaaaa acaagggtaa ccagtatgga ggatgaatgt ctggaactat ctgagaatct
      841 cggattttgg aaatcagact gatcatcatg agataaggaa ggaaagcact tgtaaaaagc
      901 actgtaatca caccagtccc ctgtcccaag agggtgaggt ggtagcgtaa aaccatacgg
      961 aaaaagccct ttttagtagt tgaaatcctc tccttgctgc gacgttcttt tttgaccttc
     1021 tcctcactgt taagcaggat cacgtcataa aaacgaggaa ggaccttctt tttggtcaga
     1081 taaagcagga agagagttag tcctatccaa gcgagcagac ccactaaggc ttctgtcgaa
     1141 aaaggctcca ctgctatttt gtaaaagata tgaagaggat aaaggagaaa tggaatgtct
     1201 ctaactttgt caacaatact tccaaaagtc gactgaagaa agaagataaa tattaaaggt
     1261 atgagaactc ctatcccaat catcacattc gaaaaaatag actgatactt tctgaagacc
     1321 ctagtctgag ccaagaaatg tactgccact accatcacta aagtaacaga gacaaataat
     1381 aaggtcaagg acagtagcat caaaggcaaa cccaaccaca gagaaggtgc tagcctaatg
     1441 tagaggacca gaaaataagc taggattggt acaattccag ctagagctgg caagaggaca
     1501 gacagacctt tggccattat aatctctgat tctttaaagg catagggcct ataggaggcc
     1561 aggtccttac tctcataaaa gacattgtaa aatgcagtga aagaagttga aaaggccagc
     1621 accagtaaaa tagcaaccat cgtactaaaa aaacttggca tttcctcaaa aggaaaacga
     1681 aaggctatat ttataaacat gaaaagcatc aagagactgg aaaaaatgta agaacttagg
     1741 actctagcgg aaacatttac tttttttcca gtatttttag cttgcttctt tcgtaggtta
     1801 gccagattag cttcttgaga tgaatagagg atattgatat caactaattt tttaatgacc
     1861 ttgagacgca tctgaaacct cctcttttct accagcaagg ctaaggtaga tactttccaa
     1921 agactggtct gggtggtctt tcctcaagtt ctctacacta ccacaataga tcaaatgccc
     1981 ctttttcaaa atagcaatcc gatcacagac ttgctcggct acctctagga catgagttga
     2041 aaacaagacc gtcttgcctt tttgtgcatg ttccttcatc atttgcttca aatcaaaggc
     2101 ggcctgggga tccaaaccag tcaagggttc gtccaaaacc caaatatcag gagcagacaa
     2161 gagtgcccca atgacaaaga ctttctgacg cattccgtga gaaagagttt caataacctg
     2221 atagcggttt tcagcaaaat caaaaacgtt caatagccta gctagactag tctccaagtc
     2281 agagctagtc agatcatagg atgaagcgat caattcccaa aattcattgg ccgttaagcg
     2341 taaaaataag tcaggcgagt ctgctacgta gccaatcttt cgtttgatcg ccaagcgatt
     2401 ttccgataac tcctgaccgt ctaccaaaat acgaccactg ctgggtgaaa tgatactgac
     2461 tagggatttt atggtggtcg attttccagc cccattatga ccaatcaagc ccataatctc
     2521 tccattttca atctgcaaat tgagattact caaggcctct ttatcaccat acaacttact
     2581 aacattttga aattcaatca tgggacaact cctatcttta tctgtattat acatcgctat
     2641 actagcactt tgatacaaaa aaatcaatac tttattttaa gtagttaaaa tagtttcctt
     2701 ctatcttacg caaacgtttg cgctaataga tgctttatga tagaataaag aacaagattg
     2761 acaagtaaga ggaaacatca tgcaaaatca aacactcatg caatactttg aatggtatct
     2821 gccccacgac ggtcaacact ggacgcgtct ggctgaaaat gctccacacc tagctcatct
     2881 ggggatcagt cacgtctgga tgccaccagc cttcaaggca accaacgaaa aagatgtcgg
     2941 ctatggggtc tatgacttat ttgacttagg agagttcaac caaaaaggga ctgtccgcac
     3001 caagtatggt ttcaaagaag actatcttca agccattcaa gcccttaaaa cacagggaat
     3061 tcaacctatg gccgatgtag ttctcaacca caaggctgct gctgatcaca gggaagcctt
     3121 tcaggttatt gaagtggatc ctgtagaccg tacagttgaa cttggagaac ccttcaccat
     3181 caatggctgg actagtttta ccttcgatgg tcgccaagat acctacaatg acttccactg
     3241 gcactggtac cacttcacag gtacagacta tgatgccaaa cgccgtaagt ctgggattta
     3301 tctgatccaa ggggacaaca agggctgggc taacgaggaa ttggtcgata acgaaaacgg
     3361 aaactacgac tacctcatgt atgccgacct agactttaaa catcctgaag tcatccaaaa
     3421 catctataac tgggctgatt ggttcatgga aacgactggt gtagctggtt tccgtttgga
     3481 tgccgttaag catattgact ctttctttat gcgcaacttc atccgcgata tgaaggaaaa
     3541 atatggtgac gatttctatg tttttggtga attttggaac ccagacaagg aagccaatct
     3601 ggactatctc gaaaaaacgg aagaacactt tgaccttgtc gatgttcgtc tccaccagaa
     3661 tctctttgaa gccagtcaag ctggcgcaaa ctatgacctt cgtggcattt tcacagatag
     3721 cctggttgaa ctcaagcctg acaaggctgt gacttttgtc gacaaccacg atacccaacg
     3781 aggacaagcc cttgagtcta ccgttgaaga atggttcaag ccagcagcct atgccctcat
     3841 tttgttacgc caagacggcc ttccatgtgt cttttacgga gactactatg ggatttcagg
     3901 ccagtatgct caagaagatt tcaaagaaat ccttgaccgc ctcctagcca tccgaaaaga
     3961 cttggcctat ggagaacaaa atgactactt tgaccatgct aactgtatcg gttgggtacg
     4021 ttcaggtgct gaaaatcaat ccccaatcgc agtccttatc tcaaatgacc aagaaaacag
     4081 caagtcaatg tttgtcggtc aagaatggac taatcaaacc tttgtagatt tacttggtaa
     4141 ccaccaaggt caagttacaa ttgatgagga aggttatgga caattccctg tctcagctag
     4201 atccgtaagt gtctgggcag tcaataccat ctaatagctc ataataacca agctaggtcc
     4261 aagcggattt ggcttttttg tattcacaaa aagacctacc caaatggata gatctttact
     4321 tgattacaat ttacctgcta ctgcatccaa caattcttgg atcttagctt ggttgcttcc
     4381 tcctgccatg gccatgtctg gtttaccacc accacgtcca tcgatgattg gtgctaattc
     4441 tttgacaagg tttcctgcat gaaggtcttt tgtcttgctt gctacaagga cattgacttt
     4501 gtcaccgata gcggcaacta ggacaagaag atcagagtag tctttttgtt tccagttatc
     4561 tgcaaaagta cgaagggcac cggcatcgga tacagacact tgactagcaa tgtaacgacg
     4621 accgttgact tccttagcat ctttgaagat atcgcctgcg gctgcagctg cggctttttc
     4681 tttcaactca gcattttctt tttgaagttg acgaagttgt tcttgaagtc cttctacctt
     4741 gtgaggtact tccttgactt gaggtgcttt caaggttgct gcgacagctt taagagcatc
     4801 ctcttgttca cgataggctt caaaggcttc cttaccagtc actgccaaga tacggcgagt
     4861 tcctgaaccg attccttctt ctttgacaat tttgaagaga ccaatctcag aagtgttgcc
     4921 aacatgagta ccaccacaaa gttcaataga gtagtcaccg atagtcacga cacgaacttc
     4981 cttgccgtat ttctcaccaa agagggccat agctcccatt tctttagcag tgtcaatatc
     5041 cgtttcaact gtcttcactt caagtgcttc ccaaattttc tcgttaactt gctgttcaat
     5101 cgcacgaagt tcctcagcag ttactgcttg gaagtgggta aagtcaaagc gaaggaattc
     5161 aacttcgtta agagatcctg cctgtgttgc gtggtttcca aggatattgt gaagggcagc
     5221 gtgaagcaaa tgagtcgcag tgtggttttt catgacacgg tgacggcgat tgctatcaat
     5281 tgccaaggta tattcttggt tcaaggcaag cggtgcaagg acttcaactg tatgaagggc
     5341 ttgaccattt ggggctttct gaacattggt cacagtagcc acaatcttac ctgactcatc
     5401 caagatttgt ccgtagtcag ctacctgtcc acccatttca gcataaaatg acgtttccgc
     5461 aaagataaga gaggcagttc cttctgaaac agctcctact tctgcattgt cagcaacgat
     5521 agctaccaat ttagaagaca attggctagt attgtagttg aagacacttt ctacagtgat
     5581 gttttgaaga gtttcatttt gcatacccat tgagccaccc ttgacagctg acgcacgcgc
     5641 gcgttcttgc tgttctttca tggctgcttc aaaaccttca cggtctacag tcataccagc
     5701 ttcttcagcg atttcttcag tcaattcaac tgggaaccca taagtatcat agagtttaaa
     5761 gacatcttga ccagcaatga cagattgacc tttttctttc aagtctgcca caatgccttg
     5821 ggcaaagtgt tgacctgagt gaagggtacg ggcaaatgat tcttcttcgc tcttaacgat
     5881 tttctcaata aagtcacgtt tctcaagcac ttctgggtag tagctttcca tgatttttcc
     5941 aacagttgga accaatttgt aaaggaaagg ctcgttgata cccaattttt gaccatgcat
     6001 agaagcacga cggagaagac gacgaagaac ataaccacga ccttcatttc ctggaagggc
     6061 accatcaccg atagcaaatg aaagagaacg aatgtggtct gcgataacct tgaagctcat
     6121 gttgtcgcca tcttggtcat aaaccttacc agacaatttc tcgacttcac ggataatcgg
     6181 catgaagagg tccgtttcaa agttggtctt agccccttgg ataacggcca ccaaacgctc
     6241 caaaccagcg cccgtatcaa tgttcttatg tggcaattcc ttgtattcgc tacgaggaac
     6301 agcagggtct gcgttaaatt gtgacaaaac gatgttccag atttcaatat aacggtcgtt
     6361 ttcaatatct tctgcaagca ggcgaagacc gatattttct gggtcaaagg cttccccacg
     6421 gtcaaagaag atttctgtat ctggtccaga aggtcccgca ccgatttccc agaagttgtc
     6481 ctcaattgga atcaagtgac ttggatccac tcccacttca atccagcggt tgtaagaatc
     6541 tttatcgtct ggatagtagg tcatgtaaag tttttcagca gggaaatcaa accattcagg
     6601 gcttgtcaaa agctcataag cccaagtgat agcttcgtca cggaagtaat ccccgataga
     6661 gaagttcccc agcatttcaa acatggtatg gtgacgcgca gtcttcccta cgttttcgat
     6721 gtcgttggta cggatagcct tttgggcatt ggtaatacgt ggattttcag ggataatggt
     6781 cccgtcaaag tatttcttaa gggttgctac cccagagttg atccacaaaa gagttgggtc
     6841 atttacagga accaaactta ctgatggttc tactgagtga cctttggtcg cccagaaatc
     6901 aagccacatt tggcgtactt gtgcactaga tagttgtttc atattgtctc cttattcact
     6961 tgtttaatgt gattggcttt ccagcatttc cacatagtca atcgcgacac agagggaaat
     7021 gactaggtct gcataagcgt cttcaagaac cgttacggta taggtagagg tcagatggaa
     7081 gagttccttc ttaatttccg caatcaactg atcgcgatca tccagcaatt tgaaattcaa
     7141 atcccagata ttgccctcga tacgaagacc tagattatca aactcatact tatctcgcca
     7201 gaaggtcaac ttcttacgaa tgacaaaact cgagccatcc cgaagctgaa tctcaaaacg
     7261 aggaagcaag gtcaagattt ctttactgat ctgactgact tgttcaccag ccgcatcata
     7321 gatggtaaaa gttttgggaa tcttaaaaaa tgatccctcc acctgatagg caatttctcc
     7381 cctgtcatcc ttgatagcga agcgttcgcc tccaagacga aacttttgtt tgacaagaaa
     7441 tgttttcatc aacacctcca aaaatcaaaa gacaagctca tatcacgaag ggcgaaaaac
     7501 cgcggtacca ccttcattca atgaacttgt cattctcttg ttcttatgca attgtatgat
     7561 tgagtagcat gacttcctag cttagatggc tcgcagcacc gccatttctc tggactaaga
     7621 caagtgaaaa tcaattctca actttcttat tataacgttt ttttaagctt gcgtcaactg
     7681 gaaatgatct ccgttgaatt agaccaattc cctacatctc tgattacttt ttcaggatat
     7741 attttttctt actgccattt ttctttttat cccaaatttt catattacta aacacagcta
     7801 ctagaatatt tccaaatata aaggtgccta tcacccaata tatggactca gttgttaggt
     7861 attgtcgatc caagccatca tttaaatgga atagtatagc agtttggtta acaatcataa
     7921 aggttggcca gaaacttttt ttgaaaaaag tagacatttt cattatttgt tgccgctttc
     7981 tgtaaggtta atactcaata aaaatcaaaa agcaaactag gaagctagct tcaagctgta
     8041 cttgagtacg gcaaggcaac gctgacgtgg tttgaagagt ataggcttag tatactacta
     8101 ggcaagcaaa taagcaaata aacaaataaa caactagaat agaaaaagat agggctctaa
     8161 aaactgactt ctattcctta aaaacgaacc agcttgactg attcgtcttc ttacgtttat
     8221 ctcctacttc cgatacattt taaactgtag gaagaggtcg ctatatttcc ctgtccattt
     8281 atggtcaaat ttctcataaa cttctaggtg tttcatggtt tcaacatcgg gatagaaggc
     8341 cttatcttcc tttgtttcct ctgggagcaa ttccttcgct ggtaggtttg gtgttgaata
     8401 gccgacatac tccgcatttt ggagagcatt ttcaggtttc aacataaagt tgataaaggc
     8461 ataggctgag tcttgatttt taactgtttt gggaatgacc atattgtcaa accaaagatt
     8521 gctggcctct gtcggtacca cataacgtaa attttcattt ttttctaaca tttggctggc
     8581 ttcaccagag aaggtcacgc cgattgcaac attattctga atcatgtagc ccttcatctc
     8641 gtccgcaacg atagccttga tatttggagt cagtttgtag agcttatcca ctgtctcttc
     8701 caactgctgc ggatccttgg agttgaggct gtagccgagg gaattgagtc ctagtcccag
     8761 cacctcacgc gccccatcaa aaagcatgat agaattctta tactccagct tccaaaggtc
     8821 atcccaatgc tcaggcgctt catctaccat ggtttcgttg tagacaattc ctaaggttcc
     8881 ccagaagtaa gggatggaga atttattacc tgggtcaaag gactggttga gaaactctgg
     8941 tccgatattt tcgattcctt caatttttga ataatcaagc ggaaccaaga ggtcttcgtc
     9001 cttcatcttg ttaatcatgt attcacttgg aatggcaata tcgtaggtcg ttccaccctg
     9061 ctttatctta gtgtacatgg cttcgttgga gtcaaaagcc tcgtactgaa cttgaattcc
     9121 tgtttcttct gtaaactgag tcaagagttc aggatcgata tagtctcccc agttatagat
     9181 aaccaatttt tgactatctc gactattgat tttactatct aaatgagtcg caattcccca
     9241 caagacaagg ataatcgctg caattcctgc taaaaatgaa tagatttttt tcatgcttgc
     9301 tcctccttct cacgagagat aaagtaataa cctacaacta ggataatact aaagagaaag
     9361 actagagcag aaagggcatt gatttctagc gaaatcccct tgcgagcacg agagtaaatc
     9421 tcgactgata gggttgaaaa gccatttcct gttacaaaga aggtcacggc aaagtcatct
     9481 aacgaatagg tgaaggccat gaaataacca gcaatgatag acggagtcag gtaaggaagc
     9541 atgatttcct taaacatctg aaattgacta gctcccaagt cataggccgc atgaatcatg
     9601 tcgccattca tttccttgag tcgaggcaag accatcaaga ccacgatagg aatggagaag
     9661 gccacatgac tagatagaac ggtcaaaaag ccaagtgaaa acttgagttg ggtaaagaga
     9721 atcaagaagc tagcaccaat cataacgtca ggcgcaacca tgaggatatt attgagtgat
     9781 agaaaggctt cttggtattt cttacgagac tggtagatgt aaatggcacc aaaagtcccg
     9841 ataatggtcg ctatcaaggc tgataggaag gccaagaaaa atgtctgagc caaaatcagc
     9901 atgagtctcc catctccaaa catggtttca aagtgagtcc agctaaaacc tgtaaagcta
     9961 ttcatatcat caccagcatt aaaggcatag ccaatcaagt aaaagatagg caggtagagg
    10021 accagaaaga ccagtcccag ataaaggttg gcaaattttt tcatcgttct ctcctttcct
    10081 tagtcaccca catggtgatg aacatggtca ggatgagaat cacaccgata gttgaaccca
    10141 taccatagtt gtcattggtt agaaaattct gctcaatagc cgtccccaag gtgataacgc
    10201 ggttcccacc aatcaaacgg gtcagcatga agagactcaa acttgggata aagaccgact
    10261 gaaccccact tcgcacaccg ttcatagata gagggaagat gacatgacgg aaggtctccc
    10321 acttagttgc accaaggtcg taactagcat tgatgagatt attatccata tcgtctaaga
    10381 cattgaaaat cggcaaaatc ataaagggga gctcgatgta gcttgcgaca aagataaagg
    10441 aaaaatcggt aaaaagcaac tgttgtgaac caattccgat aaattccaag aattggttaa
    10501 tagagccatt ttgaccaaaa atcccgataa aagcataggc tttaaggagc aaattgatcc
    10561 aggtaggaag gataatcagc atgagccaga gttgacggtg cttgagacgg gtcaaaaaga
    10621 gggctgttgg atagctgata agcaaggtca caaaggtcac aatccctgca taaagcactg
    10681 agttgaaact cattttgagg taggtcaagt tttgtgacgc aaagtaagat ttataatttt
    10741 ctaaactaaa ctggccttca atgttgaaaa aggattgtcc gaaaatcaag accaagggtg
    10801 ccaatacaaa gagggcaatc caaagcatgt agggcactac aaagagttta gagcttgttt
    10861 tcttcatctc tttcctcctc gatcgcattg atcagacctg cttcttgctc ttcgatttcc
    10921 acgtattctt cgatacgagc atcgaactct tcttcggttt cattgagacg catgatgtgg
    10981 atgtcttctg gttcaaagtc cagaccgatt tcctcaccca cgatggcctt acgggttgag
    11041 tggatcatcc attcatttcc aagttcgtca taggcgataa tttcataatg caccccacgg
    11101 aagagctggg tatcgacctt aacttggagc ttgccttctt caggaagggt aatgcgcaag
    11161 tcctctggac gaataacgac ctcaacaggt tcatttggct tcatcccacc atcaaccgct
    11221 tcaaagcgtt tgccgttaaa ttcgaccaag tagtcctcaa tcatggtacc tggcaagatg
    11281 tttgactccc cgataaaggt ggcaacaaag tggttgattg gctcatcgta gatgtccaca
    11341 ggggttccag actggacaat ctcgccatca ttcataacga aaatccagtc actcatggca
    11401 agagcttctt cctgatcgtg agtgacaaag acaaaggtaa tgcccaatcg ttgttgtaat
    11461 tcacgcaatt cgtactgcat gtctgttctc aatttcaagt ccagcgctga taaaggctcg
    11521 tccaacaaga ccacacgggg ttggttgatg atagcacggg cgatggccac acgctgacgt
    11581 tgtcctccag aaagtttgcg gatggaacgt ttttcataac cttccaactg aaccatcttg
    11641 agaacttccg ctacacgctg ctcaatttct ttcttatcaa ttttacgcaa gcgaagtgga
    11701 aaggcaacat tttcaaacac attcatatgt gggaacaagg cataggattg gaagacggta
    11761 tgtacgtcgc gcttattggt tggaatatca ttgatacgaa caccgtctag catgatatct
    11821 cctgtcgtcg catccagtaa acctgcaata atgtttagga tagttgattt ccccgaacca
    11881 gatgcaccta gaagggtgta gaatttccct tcttccaact caaagttgat gtctttgaga
    11941 accttggtgt tgctgtcttc aaaaacttta gagacgtttt tgaattcgat aattggtttt
    12001 ttcaattggc ataaattcct tctttttcat agattaaccg atcggggctc tgtcaggtcc
    12061 ccactacctc ttgcagggag taaaaccacc tgcatacatc ttcgctaccg ataggctttc
    12121 accccctttc catgacatag cagcagcttt tcaaatacag cttcctactt gctttcaccc
    12181 aagatccgga cttctctttc aagcgtaata cctgagtgtt ccttgacttt ttcgataacc
    12241 gattggatca agtcctcgta gtctttggcc gttccatctg cgacattgat cataaatcct
    12301 gcatgctttt ctgacacttc tacgccaccg atacgatagc ctttcaagcc agcttctgaa
    12361 attaactgac ctgcaaaatg cccgactgga cgcttaaaga ccgagccaca agatgggtat
    12421 tccaaaggtt gcttgagttc acgtaggtgc gtcaagcggt ccatttcctg cttgataacc
    12481 tgatgggttc ctggagctag ggcaaattta actgacaaga caactgcacc agactcctga
    12541 atagctgaat ggcggtaacc aaaagccaag tctttagcag acagggtttc gatttctcca
    12601 tccttggtca agaccttaca agactgcaag atgtgagcaa tctcgccacc ataggcaccc
    12661 gcattcataa agacagcacc gccaacgctt cctggaatac cacaagcaaa ctcaaagcca
    12721 gttaaactat gacggagggc aatgcgagtt gtttcaatca agttagcccc agcttctgct
    12781 tcaatggtat agccatcaac agaaacgtta ttgagcttgt cacacaagat gacaaatcca
    12841 cgaatcccac catcacgaac gatgatattg cttgcattgc caagaaccat ccaagggata
    12901 ttttcttggt tggcaaattt cacaaggcgc gccaactcaa aacgatttcg tggaaagacc
    12961 aaataatcag cctctccacc tacttttgta taactatagc tatgcaaggg ttccttaaaa
    13021 cggatatcaa ttccttctaa gatttcaagc attttttctc ttacagacat gtcactcttc
    13081 cttttacaaa attcattcca ttataccatt tttagagaca tttgacgacc ataaaaatac
    13141 cttgtttgga ttttgcataa gaaaaagagg ttcccctctt tttatgattt tttacaaaag
    13201 atttccttgg ttccataggc aaccagaacg agctccagtg ctagaatcac ttcaaccaag
    13261 actggatttg tcaaccagcc tacttggaaa agagatggtg ccagatcaaa gaaggcatgc
    13321 aagccatagg ctgctaggag ataaatccat ttcttctggc gaacagcttg gtaaacccaa
    13381 actgtcaaaa gtaattggaa accaagcgcc aagattcgct caaaaccaag caaataaatc
    13441 tgccagaccg aaagtgactg aatggttttt aacatatttt cagacagtaa ttgcataacc
    13501 tgtggattct gagtttgaac tgccgaaaga acgatgtaaa gattgagtaa actaataagg
    13561 cctagaaaaa tcaactccaa gccaccatgc cctaggccat aggccaaggc atctgccttt
    13621 tccaaacttc tctttttctc caaccatttg aagaaaacaa gacgagccgt ttcctcaaaa
    13681 aatgctgcca tggctaggcc atagataata tagataagcg gatgatcttg caagagggca
    13741 atactaccgt ctttttgagg atgcaaaatc aagatatgca ccagtttttc caaaatctgc
    13801 gaagagacaa agaaagcgac tgcacccaag cccaagacag ctagattaat ctggtatttc
    13861 tttttggcaa accaaatgct tcctatcaga aaagttagca acagcaacat ggtaataatg
    13921 atatgaatgg tcattttctt ctcctattct gccttttcaa tatctttttt catctcgtca
    13981 acattgaact tagcaaacaa gtattgacgg tcttggactg ggaaacgttg gtccaactgg
    14041 tcaactgctc ccacctcgat aatgccttcc ttgatgacaa aatccatgac atgtccaccg
    14101 aaggtcaaat catctgatat gaagtgcaga tggtagcctg ccacactgac cccatggaaa
    14161 atctcaggcg tccagaaacc aacaatagtc cccgcaacat tgtcacgact atattccggt
    14221 tgatgggttg cgacatcagc aaacttggta tcgggtgttg acttaggaat catacgcaca
    14281 tgcatatgtg aaaattcccc ccgaatcttg atagagcgga aaagattttc cccatcataa
    14341 taagactcaa ttcgttcttt caattccttg tctgtcatct caaagcgctg gcggaaaatg
    14401 acctctgcct gatgcggtac cactgcagcg taaggaataa gggcatctgg tgacacttcc
    14461 acaatttctg gctggtctcc tgaccctttg gcctgataag ccttgccatc caagacaatc
    14521 aattccccat caatggaatc caaggttccc aaaccaaggt caccatgttc tagcaattct
    14581 cctactgtca tagtaccacc ataaaggcca gccatcaagg ctccaagagt attgtattga
    14641 aataatttca ctggttcctg cacgttctta tccattcact ttcttgtctg ttattctata
    14701 aatcttactc ctaagtatac cacatttgcc cctagatgtg aacgagagaa acgctctaga
    14761 cattgccaag aaggaaaaaa aagggtacaa tgtaacaaaa tcaagggagg tctggaatga
    14821 agaaacaaag caagtacaaa gaggtcgttt cctatctgaa aaatggtatc gagtctgaac
    14881 gatttccgac gggtagtcgc ctgccttcta tccgtcaact gagccttgac tttcactgca
    14941 gcaaggacac cattcaacga gccctgctgg aattacggca cgaacaatac ctctatgcca
    15001 agccccagag cggctactat gtcctagaac aagggcaaca tcaagaccta gaaatcgagg
    15061 ttaccgacga acatgccagt gcctatgacg atttccgact ctgtgtcaat gaaaccttga
    15121 ttggacgaga aaactacctc ttcaactact atgacaatca agaaggatta gaagacctaa
    15181 gacagtccat tcacaaactc ctctttgagc aagctctcta ctgcaaggct aaccaactag
    15241 tactgacttc tggaacccaa caagccttat ttatcctctc tcaaatatcc tttcctagac
    15301 aagccaagga aatcttggtg gaacagccaa cctaccatcg gatgaatcgc ctcttgattg
    15361 cacaggggct ggactatcaa acgattgaac gaggcattga tgggattgac ttggaggagc
    15421 tggaaggcca cttcaaaaca ggaaaaatta aatttttcta caccattccc cgatttcact
    15481 atcctctggg acattcctat tctgagcaag acaaacgatc cattcttaac ttagctgcca
    15541 agtatgatgt ctatatcgta gaagacgatt atctgggtga tttggactcc aagaagggcc
    15601 aaaccttcca ctatcttgat acagaggagc atgtcattta tatcaagtcc ttctcgacca
    15661 gcctttttcc tgcccttcgt attacagcac tcattcttcc aaatgctatc aaagaagcat
    15721 ttgtggccta caaaaatatc ctagactacg acagcaacct cattatgcaa aaggccctgt
    15781 cactctatat tgacagtcaa ttgtttgaaa aaaatcgttt ggctcgcttg accaatcatg
    15841 aatcttacca aaaacaaatc gaggaaagga taactaaaac accttgtccc cttcctcatt
    15901 atcccctaca cgatggttta ttgctagacc tgagacagta tcctaaaatc gccagtctca
    15961 aacacagtca accgggcttg gacttctttg aagaggccta tttaagtacc tgtccttatc
    16021 aatttgccaa ggtgtcccta gacaatctgg aaaatgtttt aaactattta aaagcagaat
    16081 tggaatgaca tccaactctg ctttttctta ttcttcaact tcagttagac ttgctgcttt
    16141 ttcaagatag ctttggtaaa ttccttcatc cttaagtttt tggatgacct tgtctaccac
    16201 ttctttcaaa tcatcactat tttttctaag agcaacggca ttggcgtcgc cgtccttcat
    16261 cttcaagctg acagttgcga cagctaagcc agcgttttta gcagcataac taagtgcaac
    16321 aggctcatcc atatgaacag catctacttt tccagcctgc aattcattga ctgcttcacc
    16381 catattagtt agggaagtta attgagcttt tggcaattgt tccttgacca ttgattctgg
    16441 aacagtccct ttttgggctg caatattagc actttctagg ctagttaaat ccttgtattt
    16501 ttccacatca gccttacgaa ccaagaaact aatcttgttt tcatagtatg ggattgaaaa
    16561 atcaaagact tcttttctct cgtcagtagc actaattcct gcaactgcta ggtcagcctt
    16621 accagtttga agactggtca aaacattgtc aaaactcatg cttgagattt ccaacttaac
    16681 cccaagttca tcagcgatag cctgagccat gtcgatgtct gcaccgacta cctggttctt
    16741 tccatcaacc aatgattgaa attcaaaggg tgcatagtca ggactggttg ccacaactaa
    16801 tttccccttt tgcttaatgg cctcaacagc tgactgagaa ccattagaac ctgactggca
    16861 agctactaag aagaaacttg caagaaaatt acataaaaca aatatccatt tttttgattt
    16921 cataaataaa caacctctct gttaattttg tataattata acgatatcca agttacttgt
    16981 caagtgtttt ttaaattttt atctcaaaaa tattttttcg ttcaaaaaaa ggagccatca
    17041 gttgatttca agctcctttt tatacagaat taaactattt tatagttcga caatcttacc
    17101 tgtttcaaag tagacaaccc attcacagat atttttagca tagtcaccga tacgctccaa
    17161 gtaggaaata acttggaaat aatcacgacc cgtaacaatg gcttctggat ttttcttaat
    17221 ctcttcagtc gcaaggtcac ggatagtttc aaaatagtgg ttaatttgct catccatgga
    17281 ggccacccgg tatgcgtcgt caacagaacc attaagataa agatcaagtg ctgcttcaac
    17341 aacgctttta acttcacgtc ccattttttt aatttcttcc tctacagctg ggatgcgttc
    17401 ttcccccttc atacggatgg ttgcctgggc aatggctaca gcgtgatccc ccatacgctc
    17461 cacatctgat acagccttaa ggacagtcaa gactgtacgc aaatcttgag agactggttg
    17521 ttggagtgcg atcatttcaa atgatttctt ttccagtttc acttcgtatt catttacttc
    17581 tgcatcatct tcgatgacct cttttgccag gtcacggtca tgcgtgacaa aagcacgtac
    17641 cgtacgattg atttgtgaga gcacttcttg tcccatagcg tagaactggt tatgtaattt
    17701 ctctaaatct tcttcaaatt gagatcgtaa catctttcat ctccttatcc aaattttcct
    17761 gtaatatagt cttccgtttc cttgtgttgg ggatcaagga acatctgctt ggtatcatta
    17821 aattcaatca aatctccatc taggaaaaat cctgtcttat cagagatacg tgaagcttgc
    17881 tgcatggaac gggttaccag aagcatggtg tacttgtctt ttagaccata caaggtttcc
    17941 tcaattttac cagctgaaat cggatccaaa gccgaagttg gctcatccaa gaggatgatt
    18001 ttaggactag ttgccaagac acgggccacg cagacacgct gctgttgacc acctgacaat
    18061 ccaatagctg aatcatatag acgatccttg acctcatccc agatagaggc accttgcaag
    18121 gctttttcta cggcttcatc cagaacctgc ttatccttaa ttccattgat acgaagcccg
    18181 tagacaacat tctcatagat agtcataggg aaaggattag gttgttggaa aaccattccg
    18241 atttccttac gtaattcaac cgtatctgta cgcggactgt agatgttgtg accattgtac
    18301 accacggatc cagttgtggt cacctctgga ttgagatctc ccatgcggtt gagagacttg
    18361 aggagggttg acttccctga tccagatgga ccaatcaagg ctgtaatttc cttaggttgg
    18421 aaagataggg aaacactatt caaagccttc tttttattat aataaacgga caggtctgat
    18481 acctgtaaaa tcgcatctgt catacggttt cctttctaac caaagtgacc agatacatag
    18541 tcattggtgg actgtagctt ggcattttgg aaaatagttg cagtcttgtc atactcaatc
    18601 aaatcaccca agtaaaagaa gcctgtatag tcacttgcac gagcagcctg ctgcatatta
    18661 tgcgttacaa tgatgatggt aaagtctttc ttgagctcaa acatggtctc ttctagttgc
    18721 atggtcgcaa tcggatccaa ggctgaggct ggctcatcca ttaagaggat atctggctta
    18781 acagagatgg cacgagcgat acagagacgt tgttgctgac cacctgataa ggtcaaggct
    18841 gacttgtgga gatcgtcttt aacctgatcc cagagggcag cctgacgaag ggaggtttct
    18901 acgatttcat ctaggacttg cttatcctta actccagcac gttcatgcgc aaaggtaata
    18961 ttacggtaaa ttgacttagc aaatggattg gggcgttgaa aaaccattcc aatgtgttta
    19021 cgcatttcat aaacgttgat ttctggacgg ttgacatcaa ttccacgata gagaatctgc
    19081 ccagttactt tagcaatatc aatagtatca ttcatgcgat tgagactgcg taagtaggta
    19141 gatttccccg atcccgacgg accaatcaaa gctgtaattt tatttctttc aaattgcata
    19201 tcaatcccct taatggattc atttttacca tagtaaacat ggacatcctt agtagaaagg
    19261 gctacttttt cttcaggaaa ggtaaggata tgcttctcat cccagttata tgttgacatg
    19321 gcttctcctt taggcagcgg ttaatttctt gtgtagatag cttccgaact tacgagctcc
    19381 aaagttaaaa atcaggataa agatcaggag cacagcggca gaacctgctg atacaatagt
    19441 tccatctgga atagtgcctt cactattgac tttccagata tggacagcca aggtttctgc
    19501 ttgacggaag atagagatgg ggctagtcac actgaggata ttccagttag accagtcaag
    19561 agctggcgcc gattgccctg ctgtatagat cagagctgca gcttcgccaa agatacgacc
    19621 agatgccaag acgacacccg ttacaatacc tggaagcgct tctggaataa caacatgaac
    19681 cactgtctcc cagcgagaaa tcccaagagc cagaccagcc tcacgttggg tatggtgaac
    19741 gtgtttcaaa ctatcctcta cattacgcgt catctgaggc aagttaaaga ctgtcaaggc
    19801 caaggcacct gaaatgattg aaaatccata ctcaaactgg actacaaaga tcaagtaacc
    19861 aaagagaccc accaccactg atggtaaaga ggacaagatt tcaatacaag tccgcacaaa
    19921 gttggtaaca ggaccttttt tagcatattc agccaagtaa atcccagctc ccatagaaag
    19981 aggtacagaa ataatcaagg taatgaccaa taggaaaaag gaattgtaaa gctgaatgcc
    20041 aatcccacca cctgcttgaa aagcagaaga ccttccagtc aagaaagacc aagagatatg
    20101 gggcaagccc cgaaccaaga tatagagaat caaggaagcc aagattgtca caatgatgct
    20161 agcaatcgta tagaggacag ctgttgcaag tttatctaat ttcttagcgc gcataatttt
    20221 tctttcctct ttctttcgta atcaatttaa tcacactgtt aaaaactaaa ctcatcaaga
    20281 gcagtaccaa ggccagtgac cagagaacat tattatttac agttcccatg acagtgttcc
    20341 caattcccat agttaatata gaagttaaag ttgcagctgg tgtggtcaag gaagttggga
    20401 taacagctga gtttccgaca accatctgga tagctaaagc ctcaccaaag gcacgcgcca
    20461 tcccaaagac cactgcagtg aaaataccag aacgggccgc cttcaagatt acacgccaga
    20521 tagtctgcca gcgagtggct cccatagcga aactggcctc acgataataa cgaggaaccg
    20581 cacgcaagct atccgttgtc ataaaggtta cggtcggcaa aatcatgaca aagaggacgg
    20641 aaatccctga caaaatccca aaaccagtcc caccaaagac actgcgaaca aagggaacga
    20701 cgacttgcaa gccaataaat ccgtacacta ctgaaggaat cccaaccagg agttcaatag
    20761 ctggttgtaa aatcttcgcc ccttttggtg atacttcggt cataaaaact gctgcaccaa
    20821 tagcaaaggg tgttgctata agggctgaga gaatggtaac gataaaggaa cccaaaatca
    20881 taggaagggc accaaattct ttactagaag gattccaagt tcctcccaaa agaaagtcaa
    20941 agatattcac accattgaca aagaaggtcg acaagccttt ttgcgctacg aaaaccaaaa
    21001 tcatggccac aaggatgact atcaaagaaa gacaggcaaa ggtcaaacct tttcctaatt
    21061 tctccagacg agaattcttt gatggaagca acattttctt agctaattct tcttgattca
    21121 ttattgtctc ccttccaaca ctgtcacagt tccggcagca tctttttcaa ccttcatttc
    21181 cttaatcgga atatacttca atcctttgac aatcccttct tgggtctcat ccgagagaac
    21241 aaaattgaga aattctgcag ctaactcatt gggctgcccc aatgtataca tatgctcata
    21301 agaccacaag ggccaattat tgctacttat attttctgga cttaagtcat agccattcaa
    21361 cttcatgctt ttgaccgaat catctatata ggtaagagat aaataagaga tagctcctgg
    21421 actttttgat acgattgatt ttaccgctcc atttgaatcc tgctcctgac tttgcatggc
    21481 agactgacct tccataatga cagtatcaaa ggtagcacga gagccagagc cggctgcccg
    21541 attgataaca gagatgggta agtccttacc accaacctct ttccaattgg ttacctcacc
    21601 tatgaagatt tgacgaagtt gctctgtcgt taggttatca acatcaacct ccttattgac
    21661 aatcagagcc aagccagcta ccgcgacctt gtggtcaaca agagcagaag catcaattcc
    21721 gtctttttcc tcagcaaata catctgagtt tcctatatca actgccccag actgaacctg
    21781 ggacaagcct gtaccagaac ctcccccttg gacattgacc gtttttccaa catggatcgt
    21841 gccaaattca tctgccgcta cttcaaccaa gggttgcaag gcagttgagc caacagccgt
    21901 tatggattct ccacgatcaa tccagctagc acagcctact aaacaagccg tcagccaaaa
    21961 agcgataaga gacagagcaa gcttttttct ttttttcact gtttttctcc tcgaaaataa
    22021 ttatgaatac tgtgaatttt ttaagtagtt ctttatgagt tgacgcatga attcttacca
    22081 aatttctgcg caattgatta tttatataat ataggctata ttactctttc ctaacctcct
    22141 tttttcatat gtggataaaa tctcttgtct atcccttccc ccattgtcac ccattatagt
    22201 catttcgtgt ctctttttcc cctttttaat gcaagggaaa ttactctcct tagatgataa
    22261 tccaaaagct agaaaggtat ctcaaacctc tctactctcc cagactagtt tacaactaaa
    22321 aggaaaagat tctattttat gagaaatcta gtttacaagc ggtaagaacg ctaataacta
    22381 aacttcttgt actctttaaa aatctcttca aaccagtgtt ttgagctatc tatggctagc
    22441 ttcctagttt gctctttgat tttcattgag tagtaaaact acatgtaatg gcaatcaaga
    22501 tatcaagaat catcctacta aaaaaatcca tactttcact ataacataga ataagatatt
    22561 tgactagcat tttcatttga atctgaggcc ttttggaaaa taatttttca aaacatttcc
    22621 agtaaccttt gcaaagccca agccattgcc tttaaccaaa acttggtacc aaccatttgg
    22681 cagactttct gccagctgaa cggtttctcc agccgcatac ttgacaaacg cttcttggcc
    22741 aatttcaacc gactgttcga cctgactcgg tttcaaggct aaaccaagag cgaaactggg
    22801 ctcaaagcgt ttcttcttaa aagtgcccag atgcagtcca ttgcgagcaa tcttgagctt
    22861 ccctaaatct ggcaaaagtt ctggcaagag ataaagctgg tctccaaaag tctgcaagat
    22921 acccggtaga ttgaccttca aatggttttg ggcaaattcc tgccacaagg caacttgttc
    22981 acggctgagg ttactcttac ttgccttaaa tttaggagct ggattgttac ccttaaactg
    23041 tagatgggca acaaactgac cctctccctt aaactgatga gggtacatcc gagccgtttc
    23101 tggcaggtca ataccagcta ccattccatt gatatgctct actggaaaca agtcaaaatc
    23161 atactcttcc agcaaccaat tgacaatctc ttcgttttcc tcgggtgccc aggtacaggt
    23221 cgaataaacc agacgaccac cttcagctaa catggtcact gcatcctcca gaatttctct
    23281 ttgcaagcca gcacattgac tcggataatc taagctccaa tagtccatag catcaggttg
    23341 cttacgaaac attccttcac cagagcaagg ggcatcaaga acgattaagt caaaatagcc
    23401 tttaaagacc ttgaccaagc ggtcggcaga ttcattggtc accacgacat ttgtcgctcc
    23461 aaaacgctcc atgttttcaa ccaaaatctt agcccgtttg cttgaaattt cattggaaac
    23521 aagtagcccc tctcctgcta gataggctgc cagttgagtt gatttgcccc ccggtgcagc
    23581 agccaagtcc aagaccttca taccaggact gggttgggct acttgagcca ccatttgagc
    23641 agcaggttct tgcgaataaa ctaaacctgt agcatgctca ggcgatttcc ctgaaacctt
    23701 cccatagtgg ccccaagggg tttgagtaat ggcatcagaa aaggaaagtt gctcttcttt
    23761 taagggattg acccgaaagg ccgaaaccgc ttcctcctca aaagaggcaa gaaaatctct
    23821 tgcctcatct cctagtatct ctttatattt ttcaacaaat ccttctggaa attgcattta
    23881 agttcttttc ctttcgtaaa tataggactg aatttcctcc tgcatctcaa gaggcaccat
    23941 catgaccggc tgtctggttt gaaaatcagg agcttcacca aaaagggtca caacccgata
    24001 gcccagactt tcccctaaaa tactagctgc ggcataatcc catggttgca gataagtgag
    24061 ataggccaac aaacgccctg acaaaatctt ggcaaaacta atggccgcac ttccatagac
    24121 acgaacacca agaaccgctc ggctcaaatc agccagcccc cattcattgg tttccagcat
    24181 accactattc cctgcaatga gaaaatctcc aagtggttta gttttaaaag gagctagggg
    24241 cctatcattt agacaaactg gaaattcccc accaccgtgg taacaatccc ctttgaccac
    24301 atcataaatc agaccaaact gtccctgacc attttcaaaa taagccatca taacagcaaa
    24361 atcttcctgc tgggctacaa aattattggt accatcaatg ggatcaatga cccaaacctt
    24421 gccctcttga accgaggctc gcagacaacc ttcttcagca caaatcttat cctcaggata
    24481 acgggacaaa atctcaccaa ccaagagttc ctgaacttct ttgtccagtc tggtcaccaa
    24541 atctgttgga gaggacttgg tttcaacacg caagtcttcc tgcatatggt caagaatgta
    24601 ctggcctgct ttcttaacaa gctctttagc aaattcaaat ttactttcca agagaaatct
    24661 ttcctttccc tttttctttg gcagcctgaa ctgctcggta aagtgaatag ccactaaccg
    24721 tttcaaattc tcgtcccaaa cgtttctctt cgctcttgct tggcacgacc gctttgaatc
    24781 ccttatagga gtccagtaac tttttagcct ctactttgcc ttcataggca gcttcaacat
    24841 cattaaaaaa agaaagcact gaagcaagtt cttcagtgct ccacgacaaa tctagtgggt
    24901 aactatactg tttgttcatt aactaatacc agctctcatt cttgcttctt ttagttcttg
    24961 cttacgataa ctacgaggga gaaaagcacg aatctcatct tcattaaaac cgatttgcat
    25021 acgcttggca tcaataataa ttggacgacg caaaagacta ggatactgct caatcaaatg
    25081 aagcaattcc gataccgaaa tactctctac atcaatattc aatttttgaa aaatttttga
    25141 acgagttgaa atgatgtcat cagtaccatt ttcggtcaag gaaaggatgt gttgcaattc
    25201 ttttcttgtt aaaggactgg tcataatatt gtgttccaca aagggaacct tatgtttttc
    25261 taaccaggcc ttagccttac gacatgatgt acagctcggt gatagaaata gtgtaatcat
    25321 gcttttctct tcttatctat actttgctac ttctattata caaaaaaata aagcgcttga
    25381 ctagggattt ttagaaaaaa agcctatttt ttcaagaaaa ataggctttt tgcgaacgat
    25441 tgacacaatt ggatttggtt aattcactct taacgatggt tttaaatgat atatattttt
    25501 atatatgtaa attaaaaaca tctttccttt cacttcctac gacttttcag atacagatag
    25561 ccaaagaagt tttcatagag ggcaaaaaag aggaggaagg catgaagaaa gaaggtctct
    25621 ggcaaaatca taataacagg atccttggct ggatcaaaaa gccaggtatc atctcccaca
    25681 aagagaattt gatggaaaag agtaaagaat tggtcaaaac caatcaaaac tcccccaagt
    25741 ccaatcatca caggtaagac tactagagcc aggagacttt ttcgataaag agacaaaaag
    25801 ttctttttca caatcctatt gacaaagaca tagaaacttg gcagtgtcac tagagctact
    25861 agctgaacca aatgaaagag attcttgacc actgcgaaat ggtgcagacc agctgctgac
    25921 gaacgaaaat caggcatctg taagacctga ctaaaaggat tggtcagata attcatcaag
    25981 atatgaaaat tgtattgaat ggtttctggt tttagataga ctcgattcgt taagtttagc
    26041 cactgaatct ccataggata gaaaatccaa gccagataaa tggtcagaag gattgagagg
    26101 gagaggagaa agagcataga gccccaaaag gtcaatttag ttttcatcaa aatcccactc
    26161 cgcaaggcta gaaaccacat gtgtcggtgc gattggcagg ccagctactt cttctgcctt
    26221 agtaaaacct gtcgtcacca agagcgttgg aatgccattg tcaatcccag cccggatatc
    26281 agtcaaataa ttgtccccaa ccatgattaa ctcttcacgt tccaaaccta agtgctcaac
    26341 cgccttgtcc ataatgatgg cattgggttt tccgatataa accggcttca ctcgtgtcgc
    26401 tacttcaagc agcgtaatca gtgagccagc acctggcaaa agaccgcgtt ccgtcgggat
    26461 gttgaggtca ggattggttc cgataaaatg ggcacccttt tgaatagcaa gagttgctgt
    26521 ggcaaatttt tcatagtcga cttgccaatc cagaccaact accacgtagg cagggttttc
    26581 cttgtcttcc acataaccag ccgccttgat ggcttccttg agtcctgctt ctccgacgac
    26641 atagacggtc ttttcaagcc ccaaatcatt catatagtcg atggttgcca aagtcgctgt
    26701 gtagacagtc gataggggcg tatcgatatt aaaattctga gccaacatct ccttaacact
    26761 ctctagagtg cgagttgtat tgttggttac aaagagatag ggaatgcccc gcttttgcaa
    26821 ttcatgaaca aaagtctctc cagcagggat tcggtctttc cccttataaa tggttccgtc
    26881 taaatcaatt aaatagcctt tatatttcat ctatttctcc ctaagccttt tttatttctt
    26941 gccaagtaat gattgcttgg gcattgataa ccccatcact tgtaatttca tgcttgcttt
    27001 ccagtccagt ccgttcaaca accgatgtaa tcactccacc tggtcgaact tccttgacat
    27061 acttgaggtt gattttcttg ggaatatagt gggtcaaaaa atccgctccc atgacctcaa
    27121 aaatccagtc caagtattta ctgttattga catgaccatt catatccaag tcgtaaaaac
    27181 gaacatggta atccttgctg atcggttctt ccaaggactc atacttcggt ccacggataa
    27241 gttttttatc aaaatcagac tggtaaggag ccacaatctc aggttcaaca gcatggactt
    27301 ttcgactgtc gcggtccatg agaacaaagg tcgccatcat atggatgagc tcctgccccg
    27361 cttcattata aatagtaaag cgacggtagc aaaaaagtcg attgtagctc aaggcttccg
    27421 tttcgatggt aatttcttcc gcaaaacgag gcaaacgaac cacctcaata tcatattctg
    27481 cgataatcca gaccagatta tagtcttcca aaatggcctt atcactaact cccagttcaa
    27541 tcgactgcat ccctgaaact tgcagtgaca gcaaaatcac atctggaagt ttgatatgac
    27601 cgttcatatc agccatatca aaaggaattt tcattttcat ttgataagtt aagcccatga
    27661 tcctactcca aaataaatcg ttctgctaca gtatctccca aaaagagacc tctctttgtc
    27721 atgcgaacgt ggtcaccctc aatctgcatg aggccttgtt gaaccaaatc tctgacaatt
    27781 tctccataaa gtccagcaaa agactgtcca aatttttcct caaatcgcgc catggaaacc
    27841 ccggatttct tgcggagtcc caagaacatt tcttcttcca tttgctcctt ttgactcagg
    27901 tgatcttctg taatacaagc attgccttcc tcaaccgcac tgagataatg acgaatggga
    27961 ccatgatttt tatagcgtac tccattgaca taaccagatg cccctgcacc aataccatag
    28021 tattcagcat tgtcccagta catgagattg tgacgacttt caaagccggg tttggagaaa
    28081 ttagaaatct cataatgctc aaaacccgct cgctccagct ctgcaatgat gtactcaaac
    28141 atctccgctt ctagttcctc cttaggcaga ggcaatttcc cacgtcgcat ccggttcata
    28201 aagaccgtat ggttttctaa aatcaaacta tacaaactca tgtggggaat atccagtcca
    28261 atggctttag ccacattttc ctttacttgc tccatggtct gaccaggcag agcataaatc
    28321 aaatcaatgg agatgttgtc aaaaccagcc agtttcaggc gatcgatatt ttcataaata
    28381 tccttctcca aatgactgcg cccaatcttt ttcaacatct tatcatcaaa ggtctggaca
    28441 cctagcgaaa cacgattgac agccgaattt ttcaaaacaa ctatcttatc cgcatccaaa
    28501 tcgcctggat tggcttcaat ggtcaactct tccaagacag acaagtccaa gtttttagtc
    28561 aagccattca gtaacacctc cagttgcgga gccgacaggg ctgtcggtgt tccaccaccg
    28621 atataaaggg ttgacaactt ttcaatatca taagaacgaa actcttccag cagatgctct
    28681 aaatagctgt cgactggctg atttttgatg aagacctttg aaaaatcaca ataataacaa
    28741 atctgggtac aaaatgggat gtgcacatag gctgacgttg gttttttctg catagtaatt
    28801 attataccac aaagactaga ttccagataa aaatcaccat ccccagatac atagtccgtc
    28861 cggagatggt gatggtttat tcttctgtta tatcaatcac aatctcttct gagtcatcaa
    28921 gagcttcggc tttttcttgc cattgctcct tgagattatt taattgattt tttgatgctt
    28981 ctgtcgcttg aaaagcatag gatttagctt gagcaagtat actgtccaca gtgatttcac
    29041 ctgactcaac ctgttctttt gttttcagaa caaaatctgt agcctgctcc ttaacttctg
    29101 tcagtttttc acagacttgc tccttggcat actccggatc ttctctcaaa tcatctagaa
    29161 aatcttgagc ctgactgcaa acttgtttgc ccttatcact tgttaaaaac aaggcaagag
    29221 ctgcacctga aaccgttcct aaaaggattg aggataattt acccataagg attctccttt
    29281 tttatttttt gaaaaattta cttgcaagac gaagagctga cagacttgca ccagtcttga
    29341 gtgtttttga accagctgat gaagctttct tgctcaagac acgcgcatgg tcattgaggt
    29401 ctgaaacaga tagagataaa tctgcaacag cactgaagag tggatcaatc gtagccacct
    29461 tgacattgat atcatctgcc aagacattga ccttagccaa caactcattg gtgtgatgca
    29521 aggtcacatc cacatctgaa gtcaaggttt taatcgtctt ttctgtttca tcgatgacac
    29581 gaccaagctt ttgtacagta atgatcagat agaccaaaaa gacaatcaaa gctagggcaa
    29641 caagaatata tgcaacttct aacatttagt tttcctcctc tgtaatatag taaggggcct
    29701 tctttcgatt ttgataaata acgatcatta taccgagacc gataaggaca actgacagcc
    29761 attgggacac tcgaaagccg aagaacatga gactatctgt tcgcatacct tcgataacca
    29821 tacgaccgaa accataccaa atcaagtaaa aggccgtgat atgacctcgt ctgagactct
    29881 tccatttccg tctaaaaatc agaatcaagg caaagccaag cagattccat agagactcat
    29941 aaaggaaagt cggttgacgg tagctcccct caatatacat ctggtcacgg ataaagccag
    30001 gtagataatc cagattatcc actgttgcac cataagcttc ttggttaaag aaattacccc
    30061 aacgccccaa actttgagca atcataacgc taggcgccgc aatatctaga aaatcccaag
    30121 tattgatgag tttacggtca gcaaagatat agagcacaag agccccagtt atcaaaccac
    30181 cgtaaatggc caaaccacca ttccaaatgg caaaaatctc tcctaaattc tgactatagt
    30241 aatcaaatcg gaaaataaca tagtagagac gagctcctaa aatagccaag ggaaaagcta
    30301 ctaagataaa atctaaaata tcgtctggta tgatcttctt tctaggtgct tctttcatgg
    30361 tcaaataaac cgcaagaatc aagcctgtca caatacataa ggcataccaa cgaatggcta
    30421 ggggtcctag ttgaatagca attggatcaa gcattttgca cctcatttcg agcgatgaga
    30481 cttgtcagtc gttcgtcgaa caaacgggtc gcatcaaagc ccatttcctt ggcacgataa
    30541 ttcatggcag ctgcctcaat cacaacagag atattacgac ctgttttaac tggaatacga
    30601 atacgaggaa tggctacgcc agaaacttca agttcctctg cattgtttcc aagacgatca
    30661 aaggtcttat gtgtatcgta attttccaaa tagacagcaa gctgaacctg tgaagaatcc
    30721 ttgacagcac tcgcaccgta gagactcata acatcgataa taccaacccc acgaatttca
    30781 atcaagtgtt tcaaaatttc agctggttca ccccagagag taatctcatc cttggcaaag
    30841 atatcgacac ggtcatcggc taccaaacgg tgaccacgtt tgacaagctc aagacctgtc
    30901 tcgctcttac caattccact atctccctga atcaagacgc ccatcccata aatatccatc
    30961 aagacaccgt gcacactggt acgttctgcc aaacgagaat ccagatagct agataactct
    31021 ccagataaac gactggtagc tgcacggctg gttaaaatag caatcttaca ttctctagca
    31081 gcctttaaca tctcctctgg aaccaccaaa ccacgggcaa caatgactgc tggtgtctca
    31141 ggtagaaaca ttttttttaa aacttcataa cggctgttgg aaggcatgct gatcagataa
    31201 gaccactcct tcatccccaa aagttgaatc cgctctggtg tatagtagtc aaaatagcct
    31261 gtcatttcaa gaccaggtcg cgtaatatcc gctatattga tttccttttc aagcaattct
    31321 ggttcaccat agacaatgtc tagtctaagc ttttcaatca cttcttttac taaaaccgac
    31381 atcatttcct ccttcaaatg agttcttctc tctattatat caaattgtag gaggaagttt
    31441 cagatttttg caggctttgg agtatttatt taaaagaaaa aggactagat ttctctagcc
    31501 tttcatttca attagaattt tttacgttta cgagctactt ctgatttacg tttacgtttt
    31561 acagaaggtt tttcatagaa ttcacgtttg cgtgtttctt gaagagtacc agctttagta
    31621 accgcacgtt tgaaacggcg aagtgcgtcg tcaagagatt cattcttacg tactactgtt
    31681 ttagacattt ttttcactcc cttcaagttc aatatctatt atattctaca cgtaaaagga
    31741 ataattgtca agaggaaact aagtttttta ttcttcataa tgattaataa tatagttcac
    31801 catctcctcc atatctgctt cagataaagg taattcccag tttgttgttt ccattttaag
    31861 aaaagcatca ctgacttcag atttattatc tggcaacaaa attttgccgt ctttttcaaa
    31921 cataatacct atcctatcat ataagacatg aagattcttt tcattatttg gatcaatatc
    31981 aaaagactgt aaagaaatta aaatgtcatt tcctttatat gacaaatcaa tccacatatg
    32041 atttgataaa tcatatggtc ttgataaagt cccacctgat gagtaatgtt tgtttccata
    32101 tcctcgacct gtccttacaa atgtatcagt accatctttc tccttaaaaa aaattaagtt
    32161 tccatcacta tctctcttgc ttaaaagaaa gtcttttatt ctatttttct cttctagcct
    32221 aacgctctta tatgcttctt ttatttttag aaaatcttct ttattcatgt gtcctcctaa
    32281 agttaagttg aagttttata tgtctaaaac cactcactcc aaagagcaag cggttcttat
    32341 actttttatt tttcgagtaa gctaagcgct tcagcatctg cgatgatggt tacatcaggg
    32401 tgattttgga ggctacttgc aggtaggttc tcagtcactg ggccagatac tgttccggca
    32461 atggcttctg ctttcgactc accgtaagca aaaagaataa tagacttggc atccaaaatg
    32521 tttttaatcc ccattgaaat agcttgggtt gggacgtctt caatcttggt aaagaagcgt
    32581 gcattggctt cgatagtaga ctggtcaagt tctactagat gcgtttgact gtcaaatgga
    32641 gtaccaggct cattaaagcc gatatgccca ttgcgaccga ttcccaagat ttggaggtca
    32701 actggatggt cagccaaaat ttggttgtag cgttcaactt cagcttcagc attgtcctta
    32761 acaccacgag gcaagaaact ttctttaaat ggtttttggt tgaacaagtt ttcttgcatg
    32821 aagtaacgat aagactgtgg attgtcccca tcaaggccca catactcatc aaggttgaca
    32881 ctggttagat ttgaaaaatc aaggtcactc tcaacaattt ccttgtaaaa ttcaagtggg
    32941 ctacttcctg tcgcaagtcc tagagtttga gctccattag ccaatttttc cttcaaaatc
    33001 tcaaaagcaa cttttccacc ttgaacttgg ttttcaactt taataacttt catcttttca
    33061 tcctccattt ctgtctatat ttattatatg gtatagacca atttttgtca agtgaaaacg
    33121 atttaatttc taaaaaaaga gcgtccaaac ttgaaacgtg ttataatgga taggattaga
    33181 acttagaaag aatgaacaaa tatatgaata cagctgattt tgatttccac ttgccagagg
    33241 aattgattgc ccaaacgccc cttgaaaaac gtgatgcctc caaactcctc atcgtcaacc
    33301 gtgagacagg agaaatgcaa gataaacatt tccactctat tattgatatg ctggaacctg
    33361 gtgatgccct tgtcatgaac gacacccgag ttctccctgc ccgcctctat ggtcaaaaag
    33421 tggagacagg aggtcatgtg gaacttctcc tccttaagaa cactagtgga gacgagtggg
    33481 aagttctggc taaacctgcc aaacgcctca aggtcggtac tcgtatcagc tttggtgatg
    33541 gccgcctcag cgctgtcgtt acagaagaat tgacccacgg gggacgcatt gtccgctttg
    33601 aataccaagg aattttccta gaagtcttgg aaagtctggg agaaatgcct ctgccacctt
    33661 atatccacga aaaattagat gaccgtgaac gttatcaaac cgtctacgcc aaggaaagcg
    33721 gctctgctgc agcaccgact gctggtcttc acttcaccaa agaactgctg gcagaaatcc
    33781 aagctaaggg tgttcatcta gtctatctga ctctccatgt cggactcgga acctttagac
    33841 ctgtttctgt ggataatctg gacgaacacg aaatgcactc agagttctat caactttctg
    33901 aggaagctgc tgccaccctt cgctctgtca aagaaaatgg tggtcgcatc atcgctgtcg
    33961 gaaccacttc tatccgcacc ttggaaacta ttggttccaa gtttgatggg caaatccaag
    34021 cagattctgg ttggaccaat atctttatca aacctgggta tgagtggaag gtcgtggatg
    34081 ccttctcaac caacttccat ctgccaaaat caactctggt catgttggtt tctgcctttg
    34141 caggccgtga attagtctta gatgcctacc accatgccat ccaagaacac taccgcttct
    34201 tcagttttgg tgacgccatg tttatttatt gagaaagaat ttctctaatt cttctaatac
    34261 caataaatcg ctaagatatt atttcaaaga acatctacaa ttgaaactct agctagctgt
    34321 agaagacgcc tagtacattg aaattaaaat gcttccccct agcttcgaaa atattgccat
    34381 agattgcgtt gactctccaa attgattcat ctatatttta tttcagcttc ctatattttc
    34441 ttcgctgttt gtaaatcaaa atgcaagaca catgagtagc accatatttg ttactcttat
    34501 ctgtcctctc aagagactat tatgagttat ttcagaatca ttcactactt tgaccctgac
    34561 tctccttagt ctcaaaatca aagacttata ctcttcaaaa atctcttcaa accgcgtcaa
    34621 cgtcaccttg gattatatat gtgactgact tcgtcagttc tatctacaac ctcaaagcag
    34681 tactttgagc aacctgcgac tagttttcta gtttgctctt tgattttcat tgagtattaa
    34741 acaaaaagtg aacaaatctg aattctaatg tacagaagac taggcttgtt cactttttta
    34801 tagtcgctat aagatgacct tatctatagc tttttatata taattatata ttcagacata
    34861 ctattatcaa ttttgtcgca gggaggaatc tgttaacgca cccattcacc attatcattg
    34921 actctatagc catctatact tgtattgacc gctaactcac ccgatgtatt tacataatac
    34981 catttaccac caacttggaa ccattgattg actttcatag aaccgttgct gttgaggtag
    35041 taccatgaac cattaacttg tacccaacct gttgccatgg aaccatcagt attataaaaa
    35101 taccacatac cattttcttg tttccagcct gttgttggag caactgcttt agctggttct
    35161 actgctacat ctgttccttg gttagatgta acagatacag gatacgaagg aatagatgat
    35221 tgctcaggaa caacaacttt ttcaggttct ctcgtccctc tccttatacg tctttttacc
    35281 atctctttag taatttgacg agaagtagtt tcttcaattg ttccatcacg ttcatctaca
    35341 gtatagattg tagtaagagt aatttaccaa tttctcctac ttcttctact tcttgacttt
    35401 tatcaagagt tgggccatcg agatattctg tttcgattgg aatttcttgg acaagaactt
    35461 ggggcttggt tcctttttta acaactcttg tttgagagtc ttctttttga cttaaagtac
    35521 tctcagttac ttgtccactc tttccatcta catcataagt tatcgttgta actgttttcc
    35581 cattctttcc tagagtaatc tcttgctcct gtcctgcaga aaggtcattg tctgcttcat
    35641 atttagtagc aaatggaaca agaacttctt caaccttgct tttagctgga actttgataa
    35701 ctgtatccgt ggcttctttt ctatcaacag taacctgttc ggtaacatga ccagtctctg
    35761 gattaacatc gtaggtcctt gtcctagtta catagccatc ctctccatca attgtaacag
    35821 gattttcact acggtctttt gtttcatctt tttcataacg aattcgcgta cttgaaattt
    35881 tcttggttac taccttaggt ttagtcgcta cttttacaat aatatcccca ttgtcagcgt
    35941 catcatactc tattccctct tctttatctc tagtatcatc tctgacatat tgaatcccat
    36001 cagcagcatg aacaaaactt gtattcagat tcctcctaaa aataaagtta gcccgattac
    36061 cgcagaacca aaaatctttc cgagtttacg tattgcatag cgcttattag tattagattt
    36121 tgccattaca tcctacttct agtatagcat cttttctatc aaacgttaaa caatatactt
    36181 tatatataaa atagacttag aatgatatat tgattattga actaacattt taactatatc
    36241 gtaatcaatc tcatatataa aggattgcag acatctgatc taaatacatg ctaatatatt
    36301 tagatacaaa cattccaact tgataatttt cactc
//
LOCUS       DAVMAH010000018        35216 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVMAH010000018 DAVMAH010000000
VERSION     DAVMAH010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35216
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.018"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(71..880)
                     /locus_tag="VYO94_000827"
     CDS             complement(71..880)
                     /locus_tag="VYO94_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1759489.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYITPPSKEMQEWYSHSIKAYRKN"
     gene            complement(882..1685)
                     /locus_tag="VYO94_000828"
     CDS             complement(882..1685)
                     /locus_tag="VYO94_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1759490.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1695..3182)
                     /gene="tacF"
                     /locus_tag="VYO94_000829"
     CDS             complement(1695..3182)
                     /gene="tacF"
                     /locus_tag="VYO94_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV1759491.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRAFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFMYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3518..4225
                     /locus_tag="VYO94_000830"
     CDS             3518..4225
                     /locus_tag="VYO94_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV1759492.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4230..5252
                     /locus_tag="VYO94_000831"
     CDS             4230..5252
                     /locus_tag="VYO94_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1759493.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5269..6138
                     /gene="licA"
                     /locus_tag="VYO94_000832"
     CDS             5269..6138
                     /gene="licA"
                     /locus_tag="VYO94_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV1759494.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIGSAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGYYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            6128..7006
                     /locus_tag="VYO94_000833"
     CDS             6128..7006
                     /locus_tag="VYO94_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV1759495.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7018..7707
                     /locus_tag="VYO94_000834"
     CDS             7018..7707
                     /locus_tag="VYO94_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV1759496.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7803..8651
                     /gene="dprA"
                     /locus_tag="VYO94_000835"
     CDS             7803..8651
                     /gene="dprA"
                     /locus_tag="VYO94_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV1759497.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9535..10578
                     /locus_tag="VYO94_000836"
     CDS             9535..10578
                     /locus_tag="VYO94_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV1759498.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKEFLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            10745..12832
                     /gene="topA"
                     /locus_tag="VYO94_000837"
     CDS             10745..12832
                     /gene="topA"
                     /locus_tag="VYO94_000837"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV1759499.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            13053..13412
                     /locus_tag="VYO94_000838"
     CDS             13053..13412
                     /locus_tag="VYO94_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV1759500.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13505..14137
                     /locus_tag="VYO94_000839"
     CDS             13505..14137
                     /locus_tag="VYO94_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV1759501.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            14181..14837
                     /locus_tag="VYO94_000840"
     CDS             14181..14837
                     /locus_tag="VYO94_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV1759502.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TAYNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14856..15477
                     /locus_tag="VYO94_000841"
                     /pseudo
     CDS             14856..15477
                     /locus_tag="VYO94_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
     gene            15505..15939
                     /locus_tag="VYO94_000842"
     CDS             15505..15939
                     /locus_tag="VYO94_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEV1759503.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDIQDRVLVTVENRDTETIFNA
                     TGLDFDVLKASAIAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            15951..16988
                     /gene="leuB"
                     /locus_tag="VYO94_000843"
     CDS             15951..16988
                     /gene="leuB"
                     /locus_tag="VYO94_000843"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV1759504.1"
                     /translation="MAKKIVALTGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKHLSPLKPERIAGVDFVVVRELTGGIYFGDHILEERKERDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYETIHGSV
                     PDIAGQGIANPISMILSVAMMLRDSFGGYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            16985..17254
                     /locus_tag="VYO94_000844"
     CDS             16985..17254
                     /locus_tag="VYO94_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV1759505.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            17258..17617
                     /gene="leuD"
                     /locus_tag="VYO94_000845"
     CDS             17258..17617
                     /gene="leuD"
                     /locus_tag="VYO94_000845"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV1759506.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNDLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17779..18347
                     /locus_tag="VYO94_000846"
                     /pseudo
     CDS             17779..18347
                     /locus_tag="VYO94_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            18441..18506
                     /locus_tag="VYO94_000847"
                     /pseudo
     CDS             18441..18506
                     /locus_tag="VYO94_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            18669..20600
                     /locus_tag="VYO94_000848"
     CDS             18669..20600
                     /locus_tag="VYO94_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV1759507.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELMSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            20587..21903
                     /locus_tag="VYO94_000849"
     CDS             20587..21903
                     /locus_tag="VYO94_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV1759508.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKIGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEIGNL
                     AGYGALLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            22078..23064
                     /locus_tag="VYO94_000850"
     CDS             22078..23064
                     /locus_tag="VYO94_000850"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV1759509.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            23128..23199
                     /locus_tag="VYO94_000851"
     tRNA            23128..23199
                     /locus_tag="VYO94_000851"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23161..23163,aa:Arg,seq:ccg)
     gene            23382..24080
                     /locus_tag="VYO94_000852"
     CDS             23382..24080
                     /locus_tag="VYO94_000852"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV1759510.1"
                     /translation="MKELQTVLKNHFEIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            24071..27610
                     /gene="smc"
                     /locus_tag="VYO94_000853"
     CDS             24071..27610
                     /gene="smc"
                     /locus_tag="VYO94_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV1759511.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRVGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLVYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            27607..28401
                     /locus_tag="VYO94_000854"
     CDS             27607..28401
                     /locus_tag="VYO94_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1759512.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            28401..29219
                     /locus_tag="VYO94_000855"
     CDS             28401..29219
                     /locus_tag="VYO94_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1759513.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            29223..30500
                     /gene="ftsY"
                     /locus_tag="VYO94_000856"
     CDS             29223..30500
                     /gene="ftsY"
                     /locus_tag="VYO94_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV1759514.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(30545..32032)
                     /locus_tag="VYO94_000857"
     CDS             complement(30545..32032)
                     /locus_tag="VYO94_000857"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV1759515.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(32181..32921)
                     /locus_tag="VYO94_000858"
     CDS             complement(32181..32921)
                     /locus_tag="VYO94_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1759516.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(32921..35086)
                     /locus_tag="VYO94_000859"
     CDS             complement(32921..35086)
                     /locus_tag="VYO94_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1759517.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
BASE COUNT        11037 a         6121 c         7610 g        10448 t
ORIGIN      
        1 tatttcattt tctactaaaa ttatgttttt gaataacctc tatcttagta gtttgtataa
       61 tccccctcaa tcagtttttg cgataagctt taatgctatg actataccac tcttgcattt
      121 cttttgatgg tggtgttata taatcgccat acatctgggt taaaaattgg tcatattttt
      181 tgggaacagg caacatacgg ccctcaaact cagttaaaat cagttcttta aaggtatcaa
      241 ctgggaagat ttctttcatc ccttccttac cgatcccaac tcctccttca tattgaggag
      301 tgttggttac agcatttttg actagttgat caattttctt gtaaaagtag cgaggattga
      361 caaatcggag agcgtaccag ctacataatc taagaaaatc ttttagtttg ctatcaccgt
      421 gaactgctcg tgattttttg atataagcta gttgacgaag ggctacatac ttatagctct
      481 tgtcgacaat gctcaagtct gtaaatcgat caattgggaa gacatcgatg aaaaggctgg
      541 tatcatgacg cttgtactta acatggtctt ctataacagt agaagtgtcc aaaatcgatg
      601 cgaaattatg gaagtaccaa gaagatgtat cgtaggaaag aaccttgtag cgagggtgat
      661 tttcttcttc aataatcttc agtaaacgct cataatcctc acgataaagg gaaatatcaa
      721 tatcatcatc ccaaggaatc atacctttgt ggcggatggc tccaagcatg gttccataac
      781 tgagaaaata aggaatatca tgtttcttac aagtctcatc aatatagtcc agcagggcta
      841 gttgaatttc tttaatttct tttttttcta aatattgcat cctaatcctc caatttataa
      901 gcgtgaaatt catgactgta gaagcgtttt tcttctggtg gtagggtcat ataatctcca
      961 taaaattgtg tcaaaatagt atcaaatttt tcaggtgcag gaaggcttaa attctcaaag
     1021 ggtaaatcga ttgttttatc aaaggtacca cttgggaaga cttccttttc cttaaatttt
     1081 gaagggataa aagccatata ctgcccattt tcacgactat atttttgaat ttctttctcg
     1141 attttatttg caaaataacg aggagaaact ggtcgaagga gcaaccaaaa ggctgttcgt
     1201 atccaatctt ttaaaaggct atccttatag acaatatttt tatgtttact gaaagacagc
     1261 agtttgaagc tttccagttt ataacaagta tcaatgacct taggatcatc aaagcgatct
     1321 atagggaaaa tatcgataaa gataccagac tcataggttt ttgtatttcg agtatcaata
     1381 attttagtcg tactgtcggt tatcttgata aagttgttaa agtagttctt atcagtttct
     1441 aaggatagga gcttatactt gcttttttcc ttttgaaaaa tgttaataaa tcgttggtag
     1501 tcttctctag gcatggataa atcaatatcg tcgtcccaag ggataaagcc ctcatgtcga
     1561 accgccccaa tcagagtacc gtagttaata atatagttga tattgtgctt tttacagaga
     1621 gtatcaatat aatccaaaat ttctaattca atttgtttgg catcttcaac ggttagttgt
     1681 ttcattttaa actcctatga ttttttaaat ttatttttta aggctaggac atggtttaaa
     1741 aattcataga aaatgctatc ttttgtgaag acaagtagac taatataaga gatagctgat
     1801 agcaagacaa tcaaaccagt attaatcaaa aatggcaaat taatgaccat atccacagga
     1861 tacatgaaat taatcaggaa ataaattgct acaaaggaaa gtgaaaagag agagtatcga
     1921 acagtatagc taaagatatg tcccaagtgg atgagttgtt ttctatggat gaaaataata
     1981 tagaaaacaa gtagagaagt ctctgataac atagttgtca gtaagtagta ttcaggaacc
     2041 acgatatggt tgaaaaagag gagactattc aagcccaaat tgagtagccc agcaaagact
     2101 gtatagactg tgatacgttt ttcatagcca ttggtaaaga gaatttggga accaagaatg
     2161 gtatctaagg ccaggataat cgtacgaaaa gcgaagagag aggtcaagat gccgcctccg
     2221 atatattttt cactaccgta aagtaggatg gcatttggtc ctaaaaccat gagtccaaaa
     2281 ctcagtggaa tgataaagaa gttaaagatt cgactacctc tattaaccag agaaacatag
     2341 gcttctttgt ctcctttccc cagatagtaa ctgagacgag gcacactcac tccaattgca
     2401 cctgttacaa ccccagctat aacggtcaca attcgctgag ctatggtata gtaactaacg
     2461 ttgacatcaa tccctgtttt aacgaggaag aggcgatcta aaaaagtgaa gagcatattg
     2521 gcattggcaa agactaacat ggctgtcaga gggagaaaga gtggtttaaa atcacttagg
     2581 tgaatcttaa caagtttgat gtctctttta atccaaaaat aactaatcag gtagttaatc
     2641 agcgtcgata aactcatcac aagtgtatag acaacaatat cgtgttcatt tttaacaaat
     2701 aagaaaatag agaccagcat caggatacgg atgaaggcag ttttgtaaaa gagaaaactg
     2761 taattttcca gagcttcatt gacccattcg attgaaaaaa tctgggcaat gagttgaatc
     2821 cccataacaa ggtagacctt tttgacgatt ggattatcag taaagaagag aggataggct
     2881 aggatataga cagcagtggt caaaatcgta caagcgatgc acaaataaaa aagactagaa
     2941 aaggctctgt taagatcttt tttgttatcc ttgacattac tgatagccct taaaccgtag
     3001 ttatagacac cataagttgc aaagggcaag aaaaatgaca aaatagtgtc gactgagttg
     3061 aagtaaccat agtcagttcg gtccaagaca cgcgcgacat aggttccagt taggatggga
     3121 aaaataatat tcaagacacg aattcccatg taagatagag catttaattt tatacttttc
     3181 attcaattta cctcgttttt cattatatca taaagttagc taataagaaa tgaagggcag
     3241 taagtcaagt aatcactttg aagtttcaaa tcttaagttt taagttttct ttaaggaaag
     3301 tatattattc tgaaggactc taaaatttcg cagccattta ttagtaattg ctacagaatt
     3361 cctagtcatt actagaaatg gactagtttc tttgaataat agaactgcat aattctccta
     3421 ttctagaagg ggaggaccag tatttctttt atgataggac tagattgtgg tataatagag
     3481 agaataagtt tttttagtaa gacaaaggag aaaatagatg atttatgcag gaattcttgc
     3541 cggtggaact ggcacacgca tggggatcag taacttgcca aaacaatttt tagagctagg
     3601 tgatcgacct attttgattc atacaattga aaaatttgtc ttggagccaa gtattgaaaa
     3661 aattgtagtt ggtgttcatg gagactgggt ttctcatgca gaagatcttg tagataaata
     3721 tcttcctctt tataaggaac gtatcatcat tacaaagggt ggtgctgacc gcaatacaag
     3781 tattaagaaa atcattgaag ccattgatgc ttatcgtccg cttactccag aggatatcgt
     3841 tgttacccac gattctgttc gtccatttat tacacttcgc atgattcagg acaatatcca
     3901 acttgcccaa aatcatgacg cagtggacac agtggtagaa gcggttgata ctatcgttga
     3961 aagtaccaat ggtcaattta ttacagatat tccaaatcgt gctcaccttt atcaaggaca
     4021 aacacctcaa acattccgtt gcaaggactt catggacctt tatggatctc tttctgatga
     4081 agagaaggaa atcttgacag atgcatgtaa aatctttgtg atcaaaggaa aagatgtggc
     4141 cttggccaaa ggtgaatact caaatctgaa gattacaacc gtaacagatt tgaagattgc
     4201 aaaaagtatg attgagaaag actagtaaaa tgattaatca aatttatcaa ctaactaagc
     4261 ctaagtttat caatgtcaaa tatcaggaag aggctattga ccaagaaaat catatcctta
     4321 tccgtcccaa ctacatggct gtctgtcatg cggatcagcg ttactatcag ggaaaacgtg
     4381 atcccaagat tttgaataaa aagcttccaa tggcaatgat tcacgagtca tgtggaaccg
     4441 tcatttctga cccgaccgga acctacgagg ttggtcaaaa agttgtcatg attcccaatc
     4501 agtctcctat gcagagtgat gaagaattct atgaaaacta catgacaggg acccatttct
     4561 tgtctagtgg atttgatggc tttatgagag agtttgtttc tctccctaaa gatcgtgtgg
     4621 tggcttatga tgctattgaa gatacggttg cagccattac agagtttgtc agtgtgggca
     4681 tgcacgctat gaatcgtcta ttgactcttg ctcatagcaa gcgggagcgg atcgccgtta
     4741 ttggagatgg aagtttagct tttgtggttg ccaatattat caactatact ttgccagaag
     4801 cagagattgt ggttattggt cgtcattggg aaaagttgga actcttctca tttgccaaag
     4861 aatgctatat tacggataat attcctgaag atttggcctt tgaccatgct tttgaatgtt
     4921 gtggtggtga tggtactgga ccagctatta atgacttgat tcgctacatt cgtcctcagg
     4981 gaacgattct catgatggga gttagcgaat ataaagtcaa tctcaatact cgcgatgcct
     5041 tagaaaaggg cttgattttg gttgggtcat ctcgttctgg tcgcattgat tttgaaaatg
     5101 ctatccaaat gatggaagtc aagaaatttg ccaatcgtct taaaaatatc ctttatctag
     5161 aagaacctgt aagagaaatt aaagatattc atcgtgtctt tgcaaccgat ttaaacacag
     5221 cctttaaaac agtgtttaag tgggaagtat aagtactgga ggttaattgt ggagaaaatc
     5281 attaaagaaa aaatttcttc cttacttagt caagaagagg aagtcctcag tgttgaacaa
     5341 ctgggtggaa tgaccaatca aaactatttg gccaaaacaa caaataagca atacattgtt
     5401 aaattctttg gtaaagggac agaaaagctt atcaatcgac aagatgaaaa gtacaatctt
     5461 gaactactaa aggatttagg cttagatgta aaaaattatc tttttgatat tgaagctggt
     5521 atcaaagtaa atgagtatat cggatctgcg attacgcttg attcaacgtc aatcaagacc
     5581 aagttcgaca aaattgctcc aatattacaa actattcata cgtctgctaa ggaattaaga
     5641 ggagaatttg ctccttttga agaaatcaaa aaatacgaat ccttgattga agaacaaatt
     5701 ccttatgcca actatgaatc tgttagaaat gcagtcttct ccttagagaa aagactggct
     5761 gacttaggtg ttgacagaaa atcttgtcat atcgatttgg tgcctgaaaa ctttatcgaa
     5821 tcacctcaag gacgacttta tttgattgac tgggaatatt catcaatgaa tgatccaatg
     5881 tgggatttgg ctgccctctt tttagagtct gaattcactt cccaagagga agaaactttc
     5941 ttatctcact atgagagtga ccaaacaccg gtttctcatg aaaagattgc tatttataaa
     6001 attttacaag atactatttg gagtctatgg actgtatata aggaagagca aggtgcagat
     6061 tttggttact atggtgtgaa tcgttaccaa agagctgtta aaggtttggc ttcttatgga
     6121 ggatcagatg aaaagtaaaa acggagttcc ttttggcctt ctctcaggta ttttctgggg
     6181 cttgggtcta acggttagtg cttatatctt ttcgattttt acagatttgt caccctttgt
     6241 ggtggctgca gctcatgatt ttttgagcat ctttatctta ctagcttttc tcttggtaaa
     6301 agaagggaaa gttcgcctct caattttctt aaatattcgc aatgtcagtg ttatcatcgg
     6361 agccttgcta gcaggcccta tcggtatgca ggccaatctt tatgcagtta agtatatcgg
     6421 aagttcttta gcttcatctg tatcggctat ttaccctgcg atttcagttc tattggcttt
     6481 cttctttttg aagcacaaga tttcgaaaaa tactgtattt gggattgtct tgattattgg
     6541 agggattatt gcccagacct ataaggttga acaggttaat tccttctaca ttgggattct
     6601 ctgtgctttg gtttgtgcta ttgcatgggg aagtgagagt gttcttagct cctttgctat
     6661 ggaaagtgaa ctgagtgaaa tcgaagccct cttaatccgt caagtgactt cgttcttgtc
     6721 ctatcttgtg attgtgctct tctctcatca gtcatttact gcagtagcca atggacaatt
     6781 gctaggtctc atgattgttt ttgcagcctt tgatatgatt tcctatttgg cttattatat
     6841 cgctatcaat cgcttgcaac cagccaaggc tacaggcttg aacgtgagct atgtagtatg
     6901 gacagtcttg tttgcagttg tttttttggg tgcaccgcta gatatgctga ccattatgac
     6961 gtcacttgtc gtcattgctg gagtttatat tattattaaa gaataaagga gattcgtgtg
     7021 aaagccatta tcttagcagc gggattggga actcgcttgc gtcctatgac tgaaaatacc
     7081 cctaaagcct tggttcaggt taatcaaaaa cctttgattg aataccaaat tgagtttctc
     7141 aaagaaaaag gaatcaatga catcatcatc attgttggtt atcttaaaga acaattcgat
     7201 tacttaaaag aaaaatacgg tgttcgcctc gttttcaatg ataaatacgc tgactacaat
     7261 aacttttact ctctctatct tgtaaaagaa gaattggcca acagctatgt tattgatgct
     7321 gacaattatc tctttaaaaa tatgttccgc aatgatttga cacgttcgac ttattttagt
     7381 gtttatcgtg aagattgtac caacgaatgg ttcttggtct atggagatga ctacaaggtt
     7441 caagacatta ttgttgatag caaggcaggt cgcatcctta gtggtgtatc cttctgggat
     7501 gctccaactg cagaaaagat tgtcagcttt atcgacaagg cttatgcaag tggtgaattt
     7561 gttgatctct attgggacaa tatggttaag gataatatca aagagctaga tgtctatgtt
     7621 gaagaattag aaggcaatag catttatgag atcgatagtg tccaagacta tcgtaaatta
     7681 gaagaaattc ttaaaaacga aaattaaaga ttccaacatc tgacaaaata gtcggatgtt
     7741 ttttgatttt ttacgaactt ttacgaatag atagatgagt agaaaaagaa atggagttat
     7801 ttatgaaaat cacaaactat gaaatctata agttaaaaaa atcaggtttg accaatcaac
     7861 agattttgaa agtgctagaa tacggtgaaa atgttgatca ggagcttttg ttgggtgata
     7921 ttgcagatat atcaggttgc cgtaatccag ccgtttttat ggaacgttat tttcagatag
     7981 acgatgcgca tttgtcgaaa gagtttcaaa aatttccatc tttctctatt ttagatgact
     8041 gttatccttg ggatttgagt gaaatatatg atgcgcctgt acttttattt tacaagggaa
     8101 atcttgacct cctgaaattc ccgaaggtag cggtcgtggg cagtcgtgct tgtagcaaac
     8161 agggagctaa gtcagttgaa aaagtcattc aaggcttgga aaatgaactg gttattgtca
     8221 gtggtctggc caagggcatt gacacagcag ctcatatggc agctcttcag aatggcggaa
     8281 aaaccattgc agtgattgga acaggactgg atgtgtttta tcctaaagcc aataaacgct
     8341 tgcaagacta catcggcaat gaccatctgg ttctaagtga atatggacct ggcgaacaac
     8401 ctctgaaatt tcattttcct gcccgtaatc gcatcattgc tggactttgt cgtggtgtga
     8461 ttgtagcaga ggctaagatg cgttcaggta gtctcattac gtgtgagcga gcaatggaag
     8521 aaggacgcga tgtctttgct attcctggta gcattttaga tggactatca gacggttgcc
     8581 atcatttgat tcaagaagga gcaaaattgg tcaccagtgg gcaagatgtt cttgcggaat
     8641 ttgaatttta aaaatgacct aagctaaaat tctaagaaaa aatcaatttt aagagaaaat
     8701 gaacccaaca tttccataat aaaacgcata ttagcaagtt tttaacactt gataatatgc
     8761 gttttttcta agtggattag tagagtagag gatttttctc atataatact cttcgaaaat
     8821 ctcttcaaac tacgtcagct tccatctgca acctcaaaac agtattttga gctgacttcg
     8881 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgtggctag cttcctagtt
     8941 tgcgctttga ttttcattga gtataaggga aagtatagtg aattgaaata agatgtgaac
     9001 aactctatca ggaaagtcaa attaatttat agaaatattt tagcagccaa ggtgcactgt
     9061 tatagattca atacactata atttagtgta attgagaaag gagaaatgat tgtgattgat
     9121 gttggctagg ttatgttcaa tgattcctac cgtctcaaat cttgtcagta aggaaaaata
     9181 aattcttcaa aagtagagat tacaaggctt gtttaagaaa gaattcaaag accttgacaa
     9241 ataaaaataa aatggttatt ataagaaatg gtctaaaata gatgatgata cttttcgaaa
     9301 atctttttac gtcagctcag ctttgccttg ctgtgttttg agcaagctac ggttagcttc
     9361 cgagtttgat tttcatttac tagaaatgaa actgatgaga gatatcagta gacatttgag
     9421 tcaggatatt atggaaaatg ataaaaagag ctcgtgagat tggcatatca gactactaaa
     9481 gtattgagtt tgttaggatt ttagcgacta gttagctggg aaaggaagat atttgtgaca
     9541 aataataaac tgtattcgtt gatagaattt agaaataaaa tatatgaaga attagaactt
     9601 tccagaagtg atttagcgat tttactatgt gccatgctta tcgcctctat cggattaaat
     9661 atggattcga ctcccgtgat tattggagcc atgttaatct ctcctttgat gacacctatt
     9721 ctgggagtgg ggctctctct agctatattt gattttaaat tgttaagaaa atcttttaaa
     9781 atattagcta ttcaaattct tgcgagtcta atagcttcaa cactttattt ttatctttct
     9841 cccatttcgt atgctagttc ggagattgtt gctagaacct ctccgactat ttgggatgtt
     9901 ctcattgctt ttgtaggagg gatagcaggt attattggtg ctaggaaaaa agagaccaat
     9961 aatattgttc ctggtgttgc tattgcaacc gccttgatgc ctcctctttg tacagtaggt
    10021 tatgctattg cttctgctaa tctaaaattt atcataggct cctcttacct attcctcatc
    10081 aattgtagct ttattgtcat tgcgacttat ataggtgtta ggttgatgat ggttaagaaa
    10141 cattatttta aagataatga agaagactct aaaatgcgta ggattttgct tctagttgct
    10201 gttttgctga tgattccgag tttcatctct gcaacgactt tagtgagaga aacgttgaaa
    10261 aaagagttcc ttaagaaatt tatatcagag cagtttcagg ggtataatat tttgaaaaaa
    10321 acctattcta aaaagactca taccctaaag ctaaccattt caggaaatta tttgacagaa
    10381 gaagaactcg atatgatttc aagtaagaga ggtgactatg gtttaagtga tgtttctgtt
    10441 caagtttcac aattgtctga ttcagaacaa cttagtaagg aagagctggt ggagtatttc
    10501 ttccagtata tcaaggataa ggaagcaaaa gaaaaggaga aagccaataa atttgataca
    10561 gagtctgagg agcaataatt tcttgagaat agctggtttc tctcgtgagt cttctatgta
    10621 tatcaaagga agactgaggt tttaagtata aaacttttct tctattatag tagctaagtc
    10681 ttgacagggt tcaaaaaatg gtttacactt tataaagttt attactttga aaaggtgtga
    10741 tactgtggct acggcaacaa aaaagaaaaa atcaacagtt aaaaaaaatc tagtcatcgt
    10801 ggagtcgcct gctaaggcca agacgattga aaaatatcta ggcagaaact acaaggtttt
    10861 agccagtgtc gggcatatcc gtgatttgaa gaaatccagt atgtccgtcg atattgaaaa
    10921 taattatgaa ccgcaatata tcaatatccg aggaaaaggc cctcttatca atgacttgaa
    10981 aaaagaagct aaaaaagcta ataaagtttt tctcgcgagt gacccggacc gtgaaggaga
    11041 agcgatttct tggcatttgg cccatattct caacttggat gaaaatgatg ccaaccgtgt
    11101 ggtcttcaat gaaatcacca aggatgcagt caaaaatgct tttaaagaac ctcgtaagat
    11161 cgatatggac ttggtcgatg cccaacaagc tcgtcggatc ttggatcgct tggtagggta
    11221 ttcgatttcg cctattttgt ggaagaaggt caagaagggc ttgtcagcag gtcgcgttca
    11281 gtccattgcc cttaaactca tcattgaccg tgaaaatgaa atcaatgcct tccagccaga
    11341 agaatactgg acagttgatg ctgtctttaa aaagggaacc aaacaatttc atgcttcctt
    11401 ctatggagta gatggtaaaa agatgaaact gaccagcaat gacgaagtca aggaagtctt
    11461 gtctcgtctg acgagtaaag acttttcagt agatcaggtg gataagaaag agcgcaagcg
    11521 caatgctcct ttaccctata ccacttcatc tatgcagatg gatgctgcca ataaaatcaa
    11581 tttccgtact cgaaaaacca tgatggttgc ccaacagctc tatgaaggaa ttaatattgg
    11641 ttctggtgtt caaggtttga ttacctatat gcgtaccgat tcgactcgta tcagtcctgt
    11701 agcgcaaaat gaggcggcaa gcttcattac ggatcgtttt ggtagcaagt attctaagca
    11761 cggtagcaag gtcaaaaacg catcaggtgc tcaggatgcc catgaggcta ttcgtccgtc
    11821 aagtgtcttt aatacaccag aaagcatcgc taagtatctg gacaaggatc agctcaagct
    11881 atataccctt atctggaatc gttttgtagc tagccagatg acagcggccg tttttgatac
    11941 catggctgtt aaattgtctc aaaatggagt tcaatttgct gccaatggta gtcaggttaa
    12001 gtttgatggt tatcttgcca tttataatga ttctgacaag aataagatgt taccggacat
    12061 ggttgttgga gatgtggtca aacaggtcaa tagcaaacca gagcaacatt tcacccaacc
    12121 gcctgcccgt tattctgaag caacactgat taaaacctta gaggaaaatg gggttggacg
    12181 tccatcaacc tatgcgccaa ccattgaaac cattcagaaa cgttattatg ttcgcctggc
    12241 agccaaacgt tttgaaccga cagagttggg agaaattgtc aataagctca tcgttgaata
    12301 tttcccagat atcgtaaacg tgaccttcac agctgaaatg gaaggtaaac tggatgatgt
    12361 cgaagttgga aaagagcagt ggcgacgggt cattgatgct ttttacaaac cattctctaa
    12421 agaagttgcc aaggctgaag aagaaatgga aaaaatccag attaaggatg aaccagctgg
    12481 atttgactgt gaagtgtgtg gcagtccaat ggtcattaaa cttggtcgtt ttggtaaatt
    12541 ctacgcttgt agcaatttcc cagattgccg tcatacccaa gcaatcgtga aagagattgg
    12601 tgttgagtgt ccaagctgtc atcagggaca aattattgag cgaaaaacca agcgtaatcg
    12661 cctattctat ggttgcaatc gctatccaga atgtgaattt acctcttggg acaagcctgt
    12721 tggtcgtgac tgtccaaaat gtggcaactt cctcatggag aaaaaagtcc gtggtggtgg
    12781 caagcaggtt gtttgtagca aaggcgacta cgaggaagaa aagattaaat aagaggaggg
    12841 gcccgaaagt aaatttcagg ctccttttgg ttagaacttg acaaaataca tcattttatg
    12901 cgaaactaga agaagattat tttatactca atgagaatca aagagcaaat tagaaagcta
    12961 gtcgcaggtt gctcaaagca ctactttgag gttgaagatg gaagctgacc tggtttgaag
    13021 agattttcga agagtattaa ctaggagaag ttatgcgtct tatctatctg ataattggtt
    13081 ttttatcact ggccttggct attgttgggg ttgttttacc cttgttgccg acaacgcctt
    13141 tccttttgtt gtctattgct tgtttctcca gaagttccaa gcgtttcgaa gactggcttt
    13201 atcataccaa gctctatcaa acatatgtag ctgattttcg cgagactaag tctattacgc
    13261 gtgaacgaaa gaaaaaaatc atcgtctcta tctacgtctt gatgggaatt tctatttatt
    13321 ttgcacctct tttaccagtc aaaatcggtc tgggtgcttt gaccatcttt attacttatt
    13381 atctcttcaa ggtcattcca gacaaagaat agttaaaaca gtagttattt gccttgataa
    13441 aattgaaagc atattcataa caatatgata taataaattt gaagtaatat tcaaggagaa
    13501 tcaaatgatt tacgaatttt gtgctgaaaa tgtgacttta cttgaaaaag cgatgcaggc
    13561 tggagctcgt cggattgaac tctgtgataa tctagcagtt ggtgggacaa cacccagcta
    13621 tggagtgact aaggcagcgg ttgaactggc agctaactac gatacaacca tcatgaccat
    13681 gattcggcca cgtggtggtg actttgtcta taatgaccta gaaattgcta tcatgctaga
    13741 agacattcgt ttgactgctc aggctggaag tcaaggggtt gtatttggag ctttaactgc
    13801 tgataaaaag ttggataagc ctaatctgga aaagttaatt gctgcatcaa aaggaatgga
    13861 aattgtcttt cacatggcct ttgatgaact aagtgatgaa gatcaaccgg aagctattga
    13921 ctggctcagt caagccggtg tcactcgtat cctaactcgt gctggtgtgt ctggcgactc
    13981 cttagaaaaa cgttttgttc actatcacag aattttggag tacgctaaag gtaaaattga
    14041 aattctacca ggtgggggga ttgaccttga aaaccgtcaa acctttatcg accaggtggg
    14101 ggtaacacaa ttgcatggta ctaaggttgt tttttaaaaa atagaaagga actgctagct
    14161 ttgggtagca gttttcactt atgtttgaaa tttttaaatc ctatcaattt aatcaagaaa
    14221 aggctcatga ttatggtttt atagaaaata gcgaagtctg gacatatagt tgccagattt
    14281 tgcaaggtga ctttgtcatg actgtgtcca tcactgctta taatgtgaac tttcaagtct
    14341 ttgaccaaga gactggtgac ctctatcctc acgttcatat ggaaagcatg aggggaagtt
    14401 ttgtcggaaa tgtccgtgag gcttgtctgg agattcttta ccagattcgg aaggcttgtt
    14461 ttgatgtgca agattttatc tgtcatcaga ctaagcgtat catgactcaa gttcaggaaa
    14521 agtatggaaa ccagttggag tatctgtggg aaaaatcgcc tgatacagct gtattgcgcc
    14581 atgaaggcaa tcaaaagtgg tatgccgtct tgatgaaaat ctcttggaat aagctggaaa
    14641 agggcagaga aggacaagtg gaagcagtca acctcaagca tgaccaagta gctaatttac
    14701 tttcacaaaa ggggatttat ccagcctttc atatgagcaa gcgctactgg attagtgtgt
    14761 cccttgatga tactttatca gatgaagaag tactggaatt gatagaaaaa agttggaact
    14821 taacctctaa aaaatgaaat attttaataa ttttcatgaa ctttcaattg gctaaatatt
    14881 ctttactgaa gaaattttca gaaaatatag gatttaccac actagaggaa tatggtgcca
    14941 tcttcaaata cctgattgag aatgtcaaga cggatcgtca gatcatctat tcgcctcact
    15001 gtcatgatga cctcggaatg gcagtggcaa atagccttgc tgctgtcaag aatggtgcag
    15061 gacgtgttga agggactatc aatggtatta gggagcgagc tggaaatgct gctttggaag
    15121 aaattgcagt ggctctcaat attcgccaag attactacca agtagaaacc agtattgtcc
    15181 taaatgagac catcaatacg tcagaaatgg tttctcgctt ctctggtatt ccagttccta
    15241 aaaacaaagc cgtcgttggt ggcaatacct tctcccacga atctggtatt caccaagatg
    15301 gagtccttaa aaatcctctc acttatgaga tcatcacacc tgaattggtt ggtgttaaga
    15361 ttccgcttgg gtcgccatgc ttttgttgag aaactgagag aattggccct agattttaca
    15421 gaagaggata tcaaaccact ctttgctaag ttcaaggcac tggccgataa gaagtaagaa
    15481 atcacagatg cagatattcg agctttggta gctggaacca tggttgaaaa tccagaaggc
    15541 ttccactttg atgatttaca acttcaaact catgcagata atgacattga agcgctcgtt
    15601 agcctagcca atatggatgg tgagaaagtc gaatttaatg cgacagggca aggttccgtt
    15661 gaagcaatct ttaacgctat cgataagttc tttaaccaat ctgttcgttt ggtgtcctac
    15721 actatcgatg cggtaacaga tggaatcgat atccaggatc gggttttggt cactgttgaa
    15781 aacagagata cagaaaccat ctttaatgca acagggcttg attttgatgt gttgaaggct
    15841 tctgctattg cctatataaa cgctaatacc tttgttcaaa aagagaatgc aggtgagatg
    15901 ggacgcagtg tttcttacca cgatatgcct agtgtgtaaa ggagaaggct atggcaaaga
    15961 aaatagtagc tctaacagga gacggaattg gcccagaaat catggaggtt ggtttagaag
    16021 ttctggaggc tctagctgaa aaaacaggtt ttgactatga gattgacaga cgaccgttcg
    16081 gaggtgcaga tattgatgca gcaggacctc ccttacctga tgaaaccctt aaggcaagta
    16141 gggaagcaga tgctatccta cttgcagcta tcggtagtcc tcagtatgat ggagcagcgg
    16201 ttcgccctga acaaggcctg atggctctcc gtaaggaact caatctttac gctaatattc
    16261 gtcctgtaaa aatctttgac agtctcaagc atttgtcacc actcaaaccg gaacgaattg
    16321 ctggtgtaga ctttgtcgtg gtgcgtgaat tgacaggcgg gatttacttt ggagatcata
    16381 ttcttgaaga gcgcaaagag cgtgatatca acgactatag ctatgaggaa gtggagcgga
    16441 ttattcgcaa agcctttgaa attgcaagaa atcgcagaaa aatcgttact agtatcgata
    16501 agcaaaatgt tctagcgacc tcaaaactct ggcggaaagt agctgaggaa gtcgcacagg
    16561 atttctcaga tgtaaccttg gaacaccagc tggtagactc agctgctatg cttatgatta
    16621 ccaatcctgc taagtttgat gttattgtaa cggagaatct ttttggagat attttatctg
    16681 atgaatcaag cgtcttatct ggtacacttg gggttatgcc atcagccagt cattctgaaa
    16741 atggaccaag tctctatgaa actattcacg gttcagtacc tgatattgca ggtcaaggaa
    16801 ttgccaatcc tatttccatg attttatcag ttgccatgat gttgagagat agtttcggag
    16861 gttatgagga tgcagagcgt atcaaacgtg ctgttgagac aagtctggcg gcaggaattt
    16921 taacgagaga tataggaggt caggcttcaa caaaggaaat gacggaagct attattgcaa
    16981 ggttatgaag ttagacgaaa aaattactct agtccttttg atttggaatg tcatcatttt
    17041 cttgatttat ggcattgaca aattcaaggc aagaagaaga gcttggcgca tccaagagaa
    17101 aatcttactc attttagccc ttacttgtgg tggttttggg gcctggttag ctggaatcac
    17161 ttttcaccac aagactcgaa aatggtactt taaaacagtt tggtttcttg ggatggtgac
    17221 cacactagta gccttatatt ttatttggag gtaatggatg gcagggtctt cgagggaaca
    17281 cgctgcttgg gctctagcgg actatggttt taaggtcgtg attgcaggat ctttcggtga
    17341 cattcattac aataatgaac tcaataatga cctgttgcca atcgttcagc ctagagaggt
    17401 tagagagaaa ctagcccagc taaaaccaac cgaccaggta actgtggact tggaacaaca
    17461 aaaaatcatc tcaccagttg aagaattcac cttcgagata gatagcgagt ggaaacataa
    17521 actcctaaat agtttggatg atatcggtat taccttgcag tatgaagagt tgattgctgc
    17581 ttatgaaaaa caacgaccag cctactggca ggattagaaa aaatagaaaa ggaaatatag
    17641 taaactgaaa taagatgtaa acaaatgaat tagagcttaa catccatttc cagcaatttt
    17701 ttagaaacta cagtggacta ttctggattc aacacattat aaaattatga caaaacacat
    17761 tcacaagaag gctacgacat tttaaaaggt gagggcggat gtatcgtttg ccctactaaa
    17821 gttggttaca ttatcatgac cagtgataag gcaggacttg agcgtaagtt cgcagccaaa
    17881 gaacgtaagc gtaacaaacc aggtgttgtt ctctgcggta gcatggatga actttgcgct
    17941 ttagcgcaac tcaacccaga aattgaagca ttctactaaa aacattggga tgaagatatt
    18001 cttcttggtt gtatccttcc ttggaaacca gaagcctttg aaaaactcaa agcatacggg
    18061 gatggccgtg aagaacttat gactgatgta cgtggtacta gctgttttgt tatcaagttt
    18121 ggaaaagcag gtgaacaatt ggctgccaag ctttgggaag aaggtaaaat ggtctacgcc
    18181 tcatctgctt caatgataaa acgattgaaa ctcgctatga gcaaggtgta atggtgtcta
    18241 tagtcgataa ggacggcaaa ctcatcccag aacaaggagg agcacgttca acttcaccag
    18301 ctccagttgt gatccgtaaa gggcttgaca ttgatatagt aaaatgaagt aagagcagga
    18361 caaattaatc aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta
    18421 ttctagtttc aatccactat aaaatcatga tgcacctgtc agatactttt aactcatggg
    18481 actaccgtca ggttgagtat tattaggata gagaagaagt ctagtgttaa ggacattaca
    18541 gctcataata ctaggctttt ttatagaaat tcttttcttt ttctatagga tatggtattc
    18601 tatgtagaaa atatatgtta ataagtaatg ccaatattta aacatcatta gtaaaaggag
    18661 ttagattgat gaataaaaga aaagttagtt tagaagattt ttataaatgg tatagtctaa
    18721 ataaagaaga gttattaaat aaggcaactg ttggtgaaaa gtttaatgat aaattaaaag
    18781 aagagtttct ccaggaatgg cctttggata ggattttaac aatgtcaatc gatgaatatg
    18841 taataggaaa gggacagcaa aataagtctt tatgctacgc tcttgagaag ggaaaataca
    18901 aaaatctatt tcttggaatt tctggtggct cagcttcaaa atttggtatt tattggaata
    18961 aaaaaacaaa caaatataaa gatcaagcta ataatgagat ttcagagttg gatcagcgat
    19021 tttcaaaatt aaaatcagat ttgtatgaaa ttatcaaaga aggtattcgt tttaactttg
    19081 aaaatcctat ttttgatatg aaaagatcaa caaatgaatt tattggtcgt tctgctatgg
    19141 tgacaaaatt actttgtatc tatactgagg gagatccttt ctttggtgta aatattaata
    19201 gtcagaaaga attttggaac cactttgttt ctcagacaaa tcaaggtgga ccttatctgc
    19261 aaaatcataa aataattgaa ctgatgtcca aaacttatcc tgagttggag ccatcgaaat
    19321 taggaactat gctttttgag tattctaagc tttttatgga aaataaggaa gacaatagta
    19381 caatggattc atcaaacaat tttcgtcatc aattaactca atctctatta aagtctccaa
    19441 accttatcct tcgtggtgct cctggcacag gaaagactta tcttgctaaa gaaattgcca
    19501 aagaattaac ggatggcaac gaagatcaaa tcggatttgt acaatttcac ccatcatatg
    19561 attatacgga ttttgtagaa ggtttaagac cagtatcaaa tggggatgga gctattgagt
    19621 ttaggctaca ggacggtatt tttaaagatt tttgtcagaa agcaaaagaa acccaattga
    19681 ttggaggaca agataatttt gatgaggctt gggattctta cttagaatat ataaatgttg
    19741 ctgaagaaaa agaatatata acaaaaacat cttacttatc tgttaatagt agacaaaatt
    19801 tgtcagtaaa ttatgatagt ggtgttccag gatggtcact acctagcaaa tatgtttacg
    19861 agttgtataa agataaaaat tataataagc aagaatacta caaaagtggt ggaaaaactg
    19921 tcctagaaac attgagaaag agatttggtt tgaaagacta tgtttcccca acagaaattg
    19981 atactgataa gaaattcgtc ttcatcatcg atgaaatcaa tcgtggggag atttctaaga
    20041 tttttggcga actctttttc tctatcgacc ctggctatcg tggtgaaaaa ggaagtgttt
    20101 ctacccaata tgcaaatcta cacgaaactg atgaaaagtt ctatatcccc gaaaatgttt
    20161 acatcatcgg aactatgaat gatattgatc gttcagtgga tacctttgat tttgctatgc
    20221 gtcgtcgttt tcgttttgtt gaagttactg ccgagggtca agttggcatg ttggataaag
    20281 agttgaatat ccatgcagaa gaagcaaaaa ttcgtctaag aaacttgaac gctgctatcg
    20341 aaaatgttca ggaattaaac agtcattatc atattggacc aagttatttt cttaagttga
    20401 aggatgtaga ttttgactat gaattactct ggtctgatta tattaagcct ctcctagaag
    20461 actacttgcg aggttcttat gatgaggttg aaactttgga aactttgaaa aaagcatttg
    20521 aactgacaaa taatgagcaa aaagatcagg cagtagctga tgacaatgaa ggcgatgaaa
    20581 acgatgatgc ggattactga taatcaacac aagattatta aagaaaaatt tgttgaagaa
    20641 tatcctaaac taagcaatct tcttttagac agaaccttgg aaagtctatc ccaagatgaa
    20701 cgtattttca tttttccaaa tgatttgact catactcctg atttggataa ggaccaaaag
    20761 atttttgaaa cagtcaatca gaaaatcaag atagggaacg tgattggttt tcttggatat
    20821 ggtcaggaaa gattaacgat ttcctcacga ttttctgatg agagtaatga ccattttttg
    20881 cattatctct taaacaaggt tcttcatatc aatctcacta gtttagatgt tgctttgtct
    20941 cgtgaagaga ggctttatca acttttgatg tatctcttcc ccaagtatct acaagctgct
    21001 attcgaaaag gtctttataa ggaataccag agattttctc ataacgacag tcatgttaag
    21061 ggagtgattg atgtaagaaa ccatctcaag aaaaatcttc ctttcacggg aaatattgcc
    21121 tacacaacga gagagttcac ctatgataat cccctcatgc agttggtccg tcacactatt
    21181 gaatacatta agaatcagaa aagcattggt caaggggtac tagataatct ctcaactagt
    21241 cgtgaaaacg tatctgaaat cgtgcgtgta acgccctctt ataaactagc tgatcgtgct
    21301 aagattattc ggggaaatca atctaaacct atacgtcatg catactttca cgagtacaga
    21361 aacttacaag aactttgtct gatgatccta aaccaagaaa agcacggttt agggtatcaa
    21421 gatcaaaaaa tctatggtat tctctttgat gttgcctggc tttgggaaga gtatgtttac
    21481 accttgttgc caaaaggttt tgtacatccc agaaataagg ataagacgga tggaatttca
    21541 gtattttctg ttgggaaacg aaaagtatat ccagattttt atgatagaga acgaaagatt
    21601 gttctagatg caaaatataa aaaactggaa ttgactgaaa aaggaatcaa ccgtgaggac
    21661 ttattccagc tgatttccta ttcttatatt ttaaaagctg agaaggctgg acttgttttt
    21721 ccgagcaagg acaaggttat tgataatgag ataggaaacc tagcaggtta tggagctttg
    21781 ttgaagaaat ggtctattcg aatccctcag aatgcctcat tctatagtac attttgtaaa
    21841 atgatggaaa attcagaaga aaattttaaa gcgattattg atgaagaagt ggggagaaaa
    21901 taatttcccc tctttctttt atttttaaca caagtaaaac ccgaacgata tattttaatt
    21961 cataaaataa tttgacaaaa actgtacttt ggtttataat gaattaagga aacgtcggaa
    22021 aaggcgtagt gatgcaagag cataggtagg tcattacaaa agaaacgaga catcgatatg
    22081 ttaaatgaat ttccaatttt tgattacgaa gatattcaat tgattccaaa taaatgtgtc
    22141 attaaaagcc gtgcagaagc ggatacaagt gtcactttag gaaatcacac ctttaaacta
    22201 cctgttgtgc cagcgaatat gcagacgatt ttggatgaaa atgtagcaga gcaactggct
    22261 aaaggtggtt acttctacat tatgcaccgt tttgatgagg caggacgcat tccttttatt
    22321 aaacgaatgc acgatcaagg gctcattgct tccatatctg tcggtgttaa ggattatgag
    22381 tatgattttg ttagccagct caaggctgat gctcctgagt atatcactat tgatattgct
    22441 catggtcatg cggatagcgt gatttctatg attcaacaca tcaagaaaga attgccagat
    22501 acctttgtca ttgctggaaa tgtgggaaca ccagaagctg tgcgtgaatt ggaaaatgct
    22561 ggtgcagatg ctactaaggt cggaatcggt cctggtaagg tttgtatcac caaggttaag
    22621 actggttttg gtacaggtgg ttggcagttg gctgctctac gctggtgtgc caaggctgcg
    22681 cgtaaaccga ttatcgctga tggaggaatt cgtactcacg gtgatattgc caagtctatc
    22741 cgcttcggtg ctagcatgat catgattggt tccctctttg caggacacat tgaaagtcca
    22801 gggaaaacga ttgaagtcga tggtgaacag ttcaaagaat attatggttc agcctcacaa
    22861 tatcagaaag gtgcttacaa aaatgtggaa ggcaaacgta tcttgcttcc tgctaaaggt
    22921 catctgcaag acactttaac tgagatggaa caagaccttc aaagtgctat ttcttatgca
    22981 ggtggacgtc aggttgctga ccttaaacac gttgattatg tgatcgtgaa aaactccatc
    23041 tggaatgggg atgcttccca ctaagacggg gtctttgacc aaaaaacttg ttattagagc
    23101 aaatttctgt tataataaaa caagtttcca cccttagtgt aatggatatc acgtaagatt
    23161 ccggttcttg agatgggggt tcgattccct cagggtggat gtaaacatcc taaaaagcct
    23221 ttaatagggc ttttttcttt atcctgaccc aaatttgccg ctaaaactga gaatctctgt
    23281 ctaaagaatt cccaaatgct ttccagtccc gttttagagt gactcagggg gctttttttg
    23341 atataataaa aaggactatt atcagttaga aagaagttgg tatgaaagaa ttacaaactg
    23401 tactaaagaa tcattttgaa atcgaatttg cagacaaaaa gttactggaa actgccttta
    23461 ctcatacgag ttatgccaat gagcaccgcc tcttaaaaat ttcacacaat gaacgcttgg
    23521 aatttttagg agacgctgtt ctacagttat tgatttcaga atatctatat aaaaaatatc
    23581 ctaaaaagcc tgaaggtgac ctatcaaaac tccgtgctat gattgtccgt gaggagagtt
    23641 tagctggttt tgcgcgtgat tgccagtttg accagtttat caagttgggt aaaggggaag
    23701 aaaaatctgg tggtcgcaat cgtgacacca ttcttggtga tgcctttgaa gcctttcttg
    23761 gtgcccttct tttggataag gatgtggcaa aggtcaagga atttatctac caagttatga
    23821 ttcctaaggt agaagcaggc gaatttgaga tgattacaga ctataaaacc catctccaag
    23881 agttgcttca ggtcaatggt gatgtggcta ttcgttatca ggtgatttct gaaacagggc
    23941 ctgctcacga taaggtcttt gatgtagaag ttcttgttga aggtaagagc atcggtcaag
    24001 gccaaggtcg ttctaagaaa ttagcagagc aggaagctgc caaaaatgcc gttgagaaag
    24061 ggctggattc atgtatttaa aggaaatcga aattcagggg ttcaagtctt ttgctgataa
    24121 gaccaaggtc gtttttgacc aaggtgtgac ggcagttgtt ggacccaatg gatctggaaa
    24181 gtccaatatt acagaaagtc tgcgttgggc tttgggggag tctagtgtca agagtctccg
    24241 tgggggcaag atgccggatg tcatctttgc tggaacagaa agtcgcaaac cgctcaatta
    24301 tgcttctgta gttgtgactc tggataatca tgacggattt atcaaggatg caggtcaaga
    24361 aatcagggtg gaacgccata tctatcgtag tggagatagc gaatacaaga ttgacggcaa
    24421 gaaagtccgt ctgcgtgata ttcatgacct cttcttggat actggattgg gacgagattc
    24481 cttctctatt atttcccaag ggaaggttga ggagattttt aattccaagc ctgaggaacg
    24541 acgagctatt tttgaagaag ctgctggagt tttaaaatac aagactcgca gaaaagaaac
    24601 cgagagtaaa ctgcagcaaa ctcaggataa tctggaccgc ttagaggaca ttatctacga
    24661 gttggataat caaatcaagc ctcttgagaa gcaagctgag aatgcccgta agtttttaga
    24721 cttggaagga caacgtaagg ctatttattt agacgttctg gttgctcaaa tcaaggaaaa
    24781 taaggcagaa ctagagtcga cagaagaaga gttggctcag gttcaagaac tcttgatgag
    24841 ttattaccaa aagcgtgaaa aattagaaga agaaaatcaa actcttaaaa agcaacgcca
    24901 agatttacag gctgaaatgg ccaaagacca aggcagtttg atggacttga ctagtctgat
    24961 tagtgattta gaaagaaaat tagccctatc gaaactggag tccgagcaag tggccctgaa
    25021 tcaacaggag gcacaagctc gtttggctgc tttggaggat aagagaaatt cactcagcaa
    25081 agaaaagtat gataaagaaa gctctttagc tctgttagag ggaaatctag tccaaaataa
    25141 tcaaaaactc aatcgtttag aagctgaatt gctggctttc tcagacgatc ctgatcagat
    25201 gattgagctc ttacgtgaac gctttgtagc tcttttacaa gaagaagcgg atgtctcaaa
    25261 ccagttgacc cgtattgaga atgagttgga aaatagtcgt cagctttctc aaaaacaagc
    25321 agatcaacta gaaaagctga aagagcaatt agctacagct aaagagaagg ctagtcagca
    25381 aaaagacgag cttgaaactg ccaaggtgca ggttcagaaa ttattggctg actatcaagc
    25441 tattgccaag gagcaagagg agcagaaaac ttcctatcaa gctcaacaaa gtcaactctt
    25501 tgaccgtctg gatagtctca aaaacaagca ggccagagct caaagtttgg aaaatatcct
    25561 gagaaatcat agtaactttt atgcaggtgt taagagtgtt ctccaagaaa aagatcgcct
    25621 aggtgggatt attggtgcag tcagtgagca tctgaccttt gatgtttatt atcaaactgc
    25681 cctagagatt gccttagggg caagtagcca gcatatcatc gtagaagatg aagagtcggc
    25741 aaccaaagct attgatttcc tcaaacgaaa cagagtcggt cgtgcaacct ttcttccttt
    25801 gaccactatt aaggcgcgta cgatttctag tcagaaccaa gatgctatcg ctgtaagccc
    25861 aggtttcctt gggatggcag atgagttggt gacttttgat actagactgg aagccatttt
    25921 caagaacttg ctagctacga cggctatctt tgataccgta gaacatgcgc gtgaagctgc
    25981 tcgacaagtt cgttatcagg ttcgtatggt gacattggat gggacagaat tacgcacggg
    26041 tggttcctat gcgggtggtg ccaatcgcca aaataacagt attttcatca agccagaact
    26101 ggagcaatta caaaaagaaa ttgctgcaga tgaagcaagc ttgggttcag aagaagcggc
    26161 tttgaagacc ttgcaagacc agatggctgc attgacagaa agattagaag ccatcaaatc
    26221 tcaaggagag caggctcgta ttcaggagca aggcttgtcc ctcgtctatc agcaaactag
    26281 tcagcaagtt gaagaactgg aaactctttg gaaactccaa gaagaggaaa tagatcgtct
    26341 ttctgaggga gattggcaag cggataagga aaaatgtcaa gagagccttg ctactatcgc
    26401 cagtgaaaag caaaatctgg aagctgagat tgaagaaatt aagtctaata aaaacgccat
    26461 ccaagaacgc tatcaaaatt tgcaggaaga ggtggcgcaa gctcgcttgc ttaagacaga
    26521 actgcaaggg caaaaacgtt atgaagtagc tgatattgag cgtttaggca aggaattgga
    26581 caatcttaat atcgaacaag aagaaattca gcgcatgctc caagaaaagg ttgacaatct
    26641 tgagaaggtt gatacagaat tgctcagtca acaggcggaa gaatccaaaa ctcagaaaac
    26701 aaatctccaa caaggtttga ttcgcaagca gtttgagttg gatgatatag aaggtcaact
    26761 ggatgatatt gccagtcact tggatcaagc tcgccagcag aatgaggagt ggattcgcaa
    26821 gcaaacacgt gctgaagcca agaaagaaaa ggtcagcgag cgcttgcgcc atctacaaaa
    26881 tcaattaaca gaccagtacc agattagcta tactgaagca ctagaaaagg cacatgaatt
    26941 ggaaaacctc aatctggcag agcaagaggt gcaggattta gagaaggcta ttcgctcatt
    27001 gggacctgtc aacttggaag ctattgacca gtacgaagaa gttcacaacc gtctggactt
    27061 tctaaatagt cagcgagatg atattttgtc agcgaaaaat ctgctccttg aaaccattac
    27121 agagatgaat gatgaggtca aggaacgctt taaatcaacc tttgaagcta ttcgtgagtc
    27181 ctttaaagtg accttcaagc agatgtttgg cggaggtcag gcagacttga tattgactga
    27241 gggcgacctt ttaacagctg gtgtggagat ttctgttcaa cctccaggta agaaaatcca
    27301 gtcgcttaac ctcatgagtg gtggtgaaaa agctctatcg gctcttgcct tgcttttctc
    27361 cattattcgt gtcaagacca ttccttttgt catcttggat gaggtggaag ctgcgctgga
    27421 tgaagccaat gttaaacgtt ttggggatta cctcaaccgc tttgacaagg acagccagtt
    27481 tatcgttgta acccaccgta agggaaccat ggcagcggct gattccatct atggagtgac
    27541 catgcaagaa tcgggtgttt caaagattgt ttcagttaag ttaaaagatt tagaaagtat
    27601 tgaaggatga caattaaact agtagcaacg gatatggacg gaaccttcct agatgggaat
    27661 ggacgctttg atatggatcg tctcaagtct ctcttggctt cctacaagga aaaagggatt
    27721 tactttgcgg tggcttcggg tcggggattt ctgtctctgg aaaaattatt tgctgatgtt
    27781 cgtgatgaca ttattttcat cgcggaaaat ggcagtttgg tagagtatca aggtcaggac
    27841 ttgtatgaag cgactatgtc tcgtgacttt tatctggcaa cttttgaaaa gctgaaaacg
    27901 tcaccttatg tagatatcaa taaactgctc ttgacgggta agaagggttc atatgttcta
    27961 gatacggttg atgagaccta tttgaaagtg agtcagcatt ataatgaaaa tatccaaaaa
    28021 gtagcgagtt tggaagatat cacagatgac attttcaaat ttacaaccaa cttcacagaa
    28081 gaaacgctag aagctggtga agcttgggtt aatgaacatg tccctggtgt taaggccatg
    28141 acaactggct ttgaatctat tgatattgtt ctggactatg tcgataaggg tgtagctatt
    28201 gttgaattag ctaaaaaact tggtatcaca atggatcagg tcatggcttt tggagacaat
    28261 cttaatgact tacatatgat gcaggttgtg ggacatcctg tagctcctga aaatgcacga
    28321 cctgaaattt tagaattagc aaagactgtg attggtcacc ataaggaacg gtcggttata
    28381 gcttatatgg agggcttata atggcagata taaaattgat tgcattggac ttggacggga
    28441 ccttgctgac tactgataaa aggctgacgg atcgtaccaa ggaaaccttg aaagctgcgc
    28501 gtgatcgtgg tatcaaggtc gtattgacaa ctggtcgtcc cttaaaagcc atggatttct
    28561 ttctccatga gttagggact gacggtcagg aagatgagta taccattact tttaatggtg
    28621 gattagttca gaaaaataca ggagaaatcc ttgataaaac agtcttttca tatgatgatg
    28681 tggcacgttt gtatgaagaa acagagaaat tatcactgcc tcttgatgcc atctcagaag
    28741 gaacagttta tcaaatccaa tcggaccaag aaagtcttta tgccaaattc aatccagctt
    28801 tgacctttgt tccagtggac tttgaagact tatctagtca aatgacctac aacaaatgcg
    28861 tgactgcctt tgctcaagaa cccttggatg cagccattca gaagatttct ccagaattgt
    28921 ttgaccaata tgaaatcttt aaatcacgtg aaatgttgct agaatggtca ccaaagaatg
    28981 ttcataaagc aacaggtttg gcaaaactaa tcagccatct tggaatcgac caaagtcaag
    29041 tgatggcttg tggtgacgag gccaatgacc tctctatgat tgaatgggca ggtcttggtg
    29101 ttgctatgca aaacgctgtt cctgaagtaa aggcagccgc aaatgtagtg acgccgatga
    29161 ccaacgatga ggaagctgtc gcctgggcta tcgaagaata tgtgctaaag gagaactaag
    29221 atatgggatt gtttgaccgt ctattcggaa aaaaagaaga acctaaaatc gaagaagttg
    29281 taaaagaagc tctggaaaat cttgatttgt ctgaagatgt tgatcctacc ttcacagaag
    29341 ttgaggaagt ttctcaggaa gaagcagagg ttgaaattgt tgaacaagct gtgttccaag
    29401 aagaggaaat ccaagacaca gttgaagaaa gtctggattt agagccagtt gtagaagttt
    29461 ctcaaaaaga agtcgaagaa tttccacact cagaagaagg gaatactgag tttctagaga
    29521 ctatagaaga aaataattct gaagttcttg aaccagaaag gcctcaagca gaagaaaccg
    29581 ttcaggaaaa atatgaccgc agtcttaaga aaactcgtac aggtttcggt gcccgcttga
    29641 atgccttctt tgctaacttc cgctctgttg acgaagaatt tttcgaggaa ctggaagaac
    29701 tgctgattat gagtgatgtt ggtgtccaag tcgcttctaa cttaacggag gaactacgtt
    29761 acgaagccaa gcttgaaaat gccaagaaac ctgatgcact tcgtcgtgtc atcattgaga
    29821 aattggttga gctttatgaa aaggatggta gctacgatga aagcatccac ttccaagata
    29881 acttgacagt tatgctcttt gttggtgtga atggtgttgg gaaaacaact tctatcggaa
    29941 aactagccca ccgctacaaa caagctggta agaaggtcat gctggttgca gcagatacct
    30001 tccgtgcggg tgcagtagct cagctagctg aatggggccg acgagtagat gttccagtag
    30061 taactggacc tgaaaaagct gatccagcca gcgtggtctt tgatggtatg gaacgtgccg
    30121 tggctgaagg tatcgatatt ctcatgattg atactgctgg tcgtctgcaa aataaggata
    30181 accttatggc tgagttggaa aagattggtc gtattatcaa acgtgttgtg ccagaagcac
    30241 cacatgaaac cttcttggca cttgatgcat caacaggtca aaatgcccta gtacaggcca
    30301 aagaattttc gaaaatcaca cctttaacgg gaattgtttt gactaagatt gatggaactg
    30361 ctcgaggagg tgtggttcta gccattcgtg aagaactcaa tattcctgta aaattgattg
    30421 gttttggtga aaaaatcgat gatattggag agtttaactc agaaaacttt atgaaaggtc
    30481 tcttggaagg tttaatctaa tcagaagcaa aaatcctgca aggcataaac ttgcaggaaa
    30541 ttttttattc taagcgacca tcttgacgat aggtgatatc tggttgccaa gtccatttgg
    30601 caccgaattt ttcaagtagg tcaaagctgg cttgaggtcc catgcttcca gctttatagt
    30661 catgaagtgg ggcaccattt tcagcccaga gcttttcaat acggtcaatc aacttccatg
    30721 acgcacaaac ttcatcccag tggctaaagt tagttgagtt gttatttagg acatcataaa
    30781 tcaatttttc gtatggttct ggagaagcac cagttgcagt cgcatctgta cgataatcaa
    30841 gtgagttagg agccaagtta aattcttctc ctacttgctt cccatttagg ctaagagaga
    30901 agccttctgt tggttgaata tagatggtca aaatatttgg agcaagtggt tctccaaaga
    30961 tagaatccat ttgtttaaag acgatgttga catgagttcc tttttcagtc agtcgtttac
    31021 ctgtacggaa aaagaaagga acaccacgga atcgatcgct gtctacaaag aaggcaccag
    31081 atgtaaaggt ttcagttgtt gattctggat tcacatttgg ctcgctacga taagagatgt
    31141 atttcatgcc atcaatctta ccagagcggt attgcccacg gataaagtgt tctttgagtt
    31201 cttcatcagt tggatgatag aggtttttaa agaccttaat cttttcagca cgaatctcgt
    31261 cttttgtgaa gcttgctggt ttgtccatgg cgaggagcga aagaagttgt agagtgtggt
    31321 tttggaccat gtcacggagg gcaccggatt ggtcatagta gccaccacgt tcttctacac
    31381 ccaagcgctc cgcaaaggta atttgaacat tgtcgataaa atccttgttc caaacgtttt
    31441 caaaaatcaa gtttgcaaag cgaactgcaa agatgctttg gatcatttcc ttaccaagat
    31501 aatggtcgat acggaaaatt tgttcttcgt caaatgttgc taggagttcg tcattcaact
    31561 tgtttgcagt tgcgtaatct gtaccaaatg gtttttcaac gatcaagcgc tcaaaacctt
    31621 tgccatcgac aatgttttca gatttgaggt gtttggcaat ggttccaaag aactgaggtg
    31681 ccatagacaa gaagaagagc ttattgtgtt cagcttggta tttttcatta agctcagctt
    31741 gtaattgacg caaagcaata taatgttccg aatcattgac atcatggctt tgatagtaga
    31801 agtggctagc aaattcttgg gcttgctcgg tactatctgc caaatcaagg atggactcga
    31861 caactacaga ttcaaaatat tccttactcc aaggtctacg ggcagttcca ataacggcaa
    31921 agtgcttgga aagattgccg gatttatata gtctaaaaag ggaagggtag agcttgcgtt
    31981 tagccaggtc tccactcgca ccgaaaattg taacaataac cttagatgac atctagctac
    32041 ctaatttcta tttttattcc tagtcttgct aggtatgagg aaacctcatt tcataaactt
    32101 aattctaaca taattttccg aaaaatcaaa aattccaata cgaggtagaa aaactgcaag
    32161 gaaatcctta cagtttgagt ttagacgttt aagaccttat ctaagaactc tttcagacga
    32221 gggtgttgtg ggttatcaaa gatttggtca ggtgttccgt cttcaaggaa ctcgccatct
    32281 gcagtaaaga taacgcggtt ggcaacctga cgagcaaatc ccatctcatg ggttacgata
    32341 atcatggtca tgccttgctc agccaattcc ttcataacgt taagtacgtc tccaaccatc
    32401 tcagggtcaa gggcagaagt tggttcatcg aagagcatga tgtctggatt cattgctagg
    32461 ccacgagcga tggccacacg ttgtttttga ccacctgata ggctatctgg attggcatta
    32521 gctttatctg ctagtccaac cttttcaagc aactccattc ccaatttctc agcttcttcc
    32581 ttagtcatca acttgtgctc aataggagca aaggtgatgt tgtccaatac agacatatga
    32641 gggaagaggt tgaagtgttg gaataccatg ccgatatttt cacggacgtg gtcaacattg
    32701 gttgtttttt cagttaaatc atagccgttc acagtgatgt gaccgctagt gacttcttct
    32761 aaaagattga ggctacggag gaaagttgac ttaccagaac ctgaaggacc gatgatacaa
    32821 acaacatctc cttcatagaa cttagtcgta attcctttta ggacttcatt ttttccatag
    32881 tgcttgtgta aatcatttac atcaattttt aattttgcca ttaacgaatc ctcttttcta
    32941 agcgttttgc tagtctagtc aaaagtgtga taattacaag atagaagata gcaaggattg
    33001 catacatctt gaaactttgg tagttacgag caatgataat cttaccagtt tggaagagtt
    33061 caaccaaacc gatagcagat acgatagttg tatctttaag agcgataacg aattggttga
    33121 caaagtttgg caacatcaat ttagttgctt gtggcaagat aatcttacgc atggtttttc
    33181 cataagagat acccaagctt cggctggctt ccatttggcc aactggaacg gcctgaatac
    33241 caccacgaac gatttcagcg atataagcag ccgcattgag tgagagggca atggttccag
    33301 ctacaaagtc gttaattggg ctttgttggc ctgtgataga ctcgatgaag tttggaattc
    33361 cccagaagat gaaggctgca agaatcatca atggaatacc acgaataacg tcaacgaaaa
    33421 tctcagagat gacgcgaaga gatttgtatg ggctaacgct aaacataccg aagataattc
    33481 cgatgacaat ggcaatagca aatgagataa gagctagagc aagagtgata ccaagaccgc
    33541 taaggagttg tttgtagttg ttttgaagca agccccagag cgttgtttcg tcaacagtac
    33601 ttgttgaagc agttgaagat tcgctagcta ggtatttgtc aagaatcttt tggaattcac
    33661 cgtttgcttt aaggtttgca agtccgttgt tgaacatttc aatcagttct ggatttgctc
    33721 cttttttaac ggcaaaggct gtttcaccga ttggagttcc agagattgga gttttcaatt
    33781 tttgaccttg gctgatagaa tatttgagaa caggttcatc atccataacg gcatcaatgg
    33841 caccagtgtt taaactgtca tacattgaag aaccatcagc aaaggttttg attttgtaac
    33901 cgtatttgct ttgattttct gttaggaagg tttgagaagc agttccgttt ttaacaccga
    33961 ctgtctttcc ttttagatct tcataagaag caatattgct tgattctttg acaccaagaa
    34021 tggtattagc agtgtagtat gattctgaga agtcaaaagt tgccttacga gcatctgtga
    34081 cagacatacc agcaatgata ccatcggctt gaccagcttg gacagcactg atagcagcat
    34141 caaaaccagg gttggtgatt tcaatttcaa aaccttggtc tttagcgatt gccttaatca
    34201 attccatatc aataccagtg tattggttgc ttgaattttg gaaaacaaaa ggtgcaaaag
    34261 aagaatcgct ggcaatgata tatttagcct taacaggaat agcttttaat cctgcgagag
    34321 tagttgtagt tggcactgct gaagatgatg aagcagtcca tttcttgata attttatcaa
    34381 gactaccatc ttttttcatt tcagccaagg cttggttaaa ttcagtaacc aggtgctcgt
    34441 atttacttcc ttttttcaca ccgaaagcaa aacttcctac agcttcacca tccatttcaa
    34501 tatggaggtc ttgaccttgg ttaatggcat attcgataac aggtttgtca tccatcatgg
    34561 catcgatggc accagcactc aagctgttgt tcattaaatc accagtgtca aatgttttaa
    34621 tagtaaagcc gtatttatct ttgattgttt caaggaaacg ttgagcggca gttccgtttt
    34681 taacaccaac ggttttgcca gttaattggt cgtacttgct aattttgtgt gactttgtag
    34741 tagcaatgac aacttttgta tcatagtaag tatcagacat ggtgaagact ttttcacgtt
    34801 ctttagtctt tgtcatccct gccatgatag cgtcggcttg cccagcttga accgcattga
    34861 ctgctgcgtc aaatccagga taggacatct gaatgttcca gcctttaatc tcagcgactt
    34921 tgttaataat gtcaacatca attcctttat aagtttgatc tgaatcttta aactcaaaag
    34981 gtgcataggc ggtatcagaa acaatcttaa tcgtttctgc tttggcaata cctaatgaga
    35041 aaattgggaa taaaattagc aaaaatgcta gaaatttttt cttcattttt agtctccttt
    35101 tccgaatatt ctctcattat atcagaaaaa gtaaaaaaag gcaaattttt atatttttcg
    35161 tgtcagaaaa tataacattg atttttcctt ttctttcttg aattgctatt aaaaag
//
LOCUS       DAVMAH010000019        34417 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVMAH010000019 DAVMAH010000000
VERSION     DAVMAH010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34417
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.019"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            585..1037
                     /locus_tag="VYO94_000860"
     CDS             585..1037
                     /locus_tag="VYO94_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1759518.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1056..2393
                     /locus_tag="VYO94_000861"
     CDS             1056..2393
                     /locus_tag="VYO94_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV1759519.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIRGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2472..3356
                     /locus_tag="VYO94_000862"
     CDS             2472..3356
                     /locus_tag="VYO94_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1759520.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3356..4189
                     /locus_tag="VYO94_000863"
     CDS             3356..4189
                     /locus_tag="VYO94_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1759521.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMTAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALVL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4207..6300
                     /gene="nanB"
                     /locus_tag="VYO94_000864"
     CDS             4207..6300
                     /gene="nanB"
                     /locus_tag="VYO94_000864"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV1759522.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPALIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGDSQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYVAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6312..7415
                     /locus_tag="VYO94_000865"
     CDS             6312..7415
                     /locus_tag="VYO94_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1759523.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7589..8287
                     /locus_tag="VYO94_000866"
     CDS             7589..8287
                     /locus_tag="VYO94_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1759524.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8306..9823
                     /locus_tag="VYO94_000867"
     CDS             8306..9823
                     /locus_tag="VYO94_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1759525.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9948..11276
                     /locus_tag="VYO94_000868"
     CDS             9948..11276
                     /locus_tag="VYO94_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1759526.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11528..12394
                     /locus_tag="VYO94_000869"
     CDS             11528..12394
                     /locus_tag="VYO94_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1759527.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12410..13249
                     /locus_tag="VYO94_000870"
     CDS             12410..13249
                     /locus_tag="VYO94_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1759528.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13521..13973
                     /locus_tag="VYO94_000871"
     CDS             13521..13973
                     /locus_tag="VYO94_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1759529.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14070..14414
                     /locus_tag="VYO94_000872"
     CDS             14070..14414
                     /locus_tag="VYO94_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759530.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVNALIGRYIKLGTY
                     AAKYGISMARSILSRVAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            14698..15342
                     /locus_tag="VYO94_000873"
     CDS             14698..15342
                     /locus_tag="VYO94_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1759531.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15511..16428
                     /locus_tag="VYO94_000874"
     CDS             15511..16428
                     /locus_tag="VYO94_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV1759532.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16446..17330
                     /locus_tag="VYO94_000875"
     CDS             16446..17330
                     /locus_tag="VYO94_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1759533.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17346..18197)
                     /locus_tag="VYO94_000876"
     CDS             complement(17346..18197)
                     /locus_tag="VYO94_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1759534.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18397..20454
                     /gene="pbp2b"
                     /locus_tag="VYO94_000877"
     CDS             18397..20454
                     /gene="pbp2b"
                     /locus_tag="VYO94_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV1759535.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20465..21061
                     /gene="recR"
                     /locus_tag="VYO94_000878"
     CDS             20465..21061
                     /gene="recR"
                     /locus_tag="VYO94_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV1759536.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21237..22280
                     /locus_tag="VYO94_000879"
     CDS             21237..22280
                     /locus_tag="VYO94_000879"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV1759537.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22364..23737
                     /locus_tag="VYO94_000880"
     CDS             22364..23737
                     /locus_tag="VYO94_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV1759538.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLFLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVESKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAVNGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENEAK"
     gene            23724..24335
                     /locus_tag="VYO94_000881"
     CDS             23724..24335
                     /locus_tag="VYO94_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1759539.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDVEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            24426..25130
                     /locus_tag="VYO94_000882"
     CDS             24426..25130
                     /locus_tag="VYO94_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV1759540.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25349..26722
                     /gene="ftsA"
                     /locus_tag="VYO94_000883"
     CDS             25349..26722
                     /gene="ftsA"
                     /locus_tag="VYO94_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV1759541.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26739..27998
                     /gene="ftsZ"
                     /locus_tag="VYO94_000884"
     CDS             26739..27998
                     /gene="ftsZ"
                     /locus_tag="VYO94_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV1759542.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            28003..28674
                     /locus_tag="VYO94_000885"
     CDS             28003..28674
                     /locus_tag="VYO94_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV1759543.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28684..29223
                     /locus_tag="VYO94_000886"
     CDS             28684..29223
                     /locus_tag="VYO94_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV1759544.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29223..29486
                     /locus_tag="VYO94_000887"
     CDS             29223..29486
                     /locus_tag="VYO94_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV1759545.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29483..30268
                     /locus_tag="VYO94_000888"
     CDS             29483..30268
                     /locus_tag="VYO94_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV1759546.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELNLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLFQDKGQTKKEKKKITVQLLLSK"
     gene            30277..31065
                     /gene="divIVA"
                     /locus_tag="VYO94_000889"
     CDS             30277..31065
                     /gene="divIVA"
                     /locus_tag="VYO94_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV1759547.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31413..34205
                     /locus_tag="VYO94_000890"
     CDS             31413..34205
                     /locus_tag="VYO94_000890"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV1759548.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAAVSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10579 a         6069 c         7496 g        10273 t
ORIGIN      
        1 aaagtatact ctaattgaaa acggtaacaa aactaattta gagaatgaaa tatagagtat
       61 ttctctctta aaagtttttg gtgaaacgag atgtagaaag gagatttagc caaagagtct
      121 attagtgcta gaataataga ttagaattat tttagaaaaa cgaagtgagc agcttataaa
      181 ttcaagtccc caaatagatt catactagta tcttttgcaa aaaataaagg gcgacttcct
      241 tcatgaatat caatttcatc tataaggaag gtagctaatt gaactaactt atttattctg
      301 tttgtcgcta gaaaaatcag acctccttgt gaagattgag gagatactga atgaaaatca
      361 aagaagaaac tagcaagcta gtagcagatt gcccaaaaca ccgctttgag gttgtagata
      421 agactgacct atataatcca aggtgaagcg actgtggttt gaagagattt tcaaagagta
      481 taggctagag agtagtgttt ttatgtcctt ctagtagaaa atgctagaca gaagaatggg
      541 gaacttggat aggagaaata gattgagaaa ggaggttaga agagatgatt attacaaaaa
      601 ttagccgttt aggaacttat gtgggagtaa atccacattt tgcaacatta atagattttc
      661 tagaaaaaac aggactagaa aatttaacag aaggttcgat tgctatcgat ggtaatcgat
      721 tgtttgggaa ttgctttact tatctagcag atggtcaagc aggggctttc tttgaaacac
      781 accaaaaata tttggatatt catttagttt tggaaaacga agaagccatg gctgttacat
      841 cgccggaaaa tgtaagcgtt acccaagaat atgatgaaga gaaagatatt gaattataca
      901 cagggaaagt ggaacagttg gttcatttga gagctggtga atgcctcatc acttttccag
      961 aagatttaca tcaacccaag gttcgtataa atgatgaacc tgtgaaaaaa gttgtcttta
     1021 aagttgcgat ttcttaatgt agaaagagaa gaacgatgaa aaaaatgaga aagtttttat
     1081 gtctagctgg aattgcgcta gcggctgttg ccttggtagc ttgttcagga aaaaaagaag
     1141 ctacaactag tactgaacca ccaacagaat tatctggtga gattacaatg tggcactcct
     1201 ttactcaagg accccgttta gaaagtattc aaaaatcagc agatgctttc atgcaaaagc
     1261 atccaaaaac gaaaatcaag attgaaacat tttcttggaa tgacttctat actaaatgga
     1321 ctacaggttt agcaaatgga aatgtgccag atatcagtac agctcttcct aaccaagtaa
     1381 tggaaatggt caactcagat gctttggttc cgctaaatga ttctatcaag cgtattggac
     1441 aagataaatt taacgaaact gccttaaatg aagcaaaaat cggagatgat tactactctg
     1501 ttcctcttta ttcacatgca caagtcatgt gggttagaac agatttgtta aaagaacata
     1561 atattgaggt tcctaaaact tgggatcaac tctatgaagc ttctaaaaaa ttgaaagaag
     1621 ctggagttta tggcttgtct gttccgtttg gaacaaatga cttaatggca acacgtttct
     1681 tgaacttcta cgtacgtagt ggtggaggaa gcctcttaac aaaagatctt aaagcagact
     1741 tgacaagcca acttgctcaa gatggtatta aatactgggt taaattgtat aaagaaatct
     1801 cacctcaaga ttctttgaac tttaatgtcc ttcaacaagc taccttgttc tatcaaggaa
     1861 aaacagcatt tgactttaac tctggcttcc atatcggagg aattaatgcc aacagtcctc
     1921 aattgattga ttcgattgat gcttatccta ttccaaaaat caaagagtct gataaagacc
     1981 aaggaattga aacctcaaac attccaatgg ttgtttggaa aaattcaaaa catccagaag
     2041 ttgctaaagc attcttagaa gcactttata atgaagaaga ctacgttaaa ttccttgatt
     2101 caactccagt aggtatgttg ccaactatta gggggattag cgattctgca gcctataaag
     2161 aaaatgaaac tcgtaagaaa tttaaacatg ctgaagaagt aattactgaa gctgttaaaa
     2221 aaggtactgc tattggttat gaaaatggac caagtgtaca agctggtatg ttgactaacc
     2281 aacacattat tgaacaaatg ttccaagata tcattacaaa tggaacagat cctatgaaag
     2341 cagcaaaaga agcagaaaaa caattaaacg atttatttga ggctgttcag tagatgtaaa
     2401 agactagaaa ataggtgggc tagtgagctg aaaagctcta gcccaatctt gtaaaagaag
     2461 ggagaaggag aatggttaaa gaacgtaatt taactcgctg gatatttgtt ttgccagcta
     2521 tgattatcgt aggattactc tttgtttatc cgtttttctc gagtattttt tatagcttta
     2581 ccaataagca tttgattatg cctaattata aatttgttgg tttggctaac tataaagctg
     2641 tgctatcaga tcccaacttc tttaatgcgt tctttaattc aattaagtgg accgttttct
     2701 cattagttgg tcaagtttta gtagggtttg tattggcttt agctcttcac agagtacgcc
     2761 acttcaagaa attatatagg accttattga ttgttccttg ggcatttcct accatcgtca
     2821 ttgccttttc ttggcagtgg attctaaacg gggtttatgg ctacttacct aatctaatcg
     2881 taaaattagg tttaatggaa catacacctg catttttgac agatagtaca tgggcattcc
     2941 tatgtttggt gtttatcaac atttggtttg gagcaccaat gattatggtt aatgtgcttt
     3001 cagctttgca aacagtacca gaagaacaat ttgaggctgc taagatagat ggtgcttcaa
     3061 gttggcaggt gttcaagttt atcgtctttc cacatattaa agtggttgta ggacttctag
     3121 ttgttttgag aactgtatgg atctttaata actttgacat tatctacctc attactggtg
     3181 gtggaccagc caatgctaca acgacgcttc caatttttgc ttacaacctg ggctggggaa
     3241 ctaaattgtt gggtcgtgct tcagcagtta cagtattgct ctttatcttc ttggtggcga
     3301 tttgctttat ctactttgct atcatcagta agtgggaaaa ggagggtaga aaataatgaa
     3361 gaagaaatcc agtatttatt tagatattct ctcacatgta cttttagttg gtgcgaccat
     3421 cgttgcaatt ttcccattgg tatggattat catatcttct gtcaaaggga aaggggaatt
     3481 aactcagtat ccaacacgat tttggcctga acagtttaca ttagattatt tcactcatgt
     3541 tatcaacgat ttgcacttca ttgataacat tcgaaacagt ttaatcattg ccttggctac
     3601 aaccctcatt gcgattatta tttctgctat gacagcctat ggtattgttc gattctttcc
     3661 taaattggga gcaatcatgt cgagactact cgtcattacc tacattttcc caccaatttt
     3721 gttagcaatt ccctattcaa ttgccattgc taaagttggg ttaacaaata gtttatttgg
     3781 cttgatgatg gtttatctat cttttagtgt tccatatgca gtttggctct tagttggatt
     3841 tttccaaaca gttccaattg gaattgaaga agcggctaga attgatggtg caaataaatt
     3901 tgttacgttt tataaagttg tgctaccgat tgtagcacca ggtattgtag caacagctat
     3961 ttatacattt atcaatgctt ggaatgaatt cctgtatgcc ttggttttga ttaacaatac
     4021 aggaaagatg acagtagcag tagcccttcg ttcacttaat ggttcagaaa tactagactg
     4081 gggagatatg atggcagcgt ctgttattgt agttcttcca tcaattattt tcttctctat
     4141 catccaaaat aagattgcaa gtggattatc agaaggatct gtgaagtaga cgaaagaagg
     4201 aaaaaaatga ataaaagagg tctttattca aaactaggaa tttctgttgt aggcattagt
     4261 cttttaatgg gagtccccgc tttgattcat gcgaatgaat taaactatgg tcaactgtcc
     4321 atatctccta tttttcaagg aggttcatat caactgaaca ataagagtat agatatcagc
     4381 cctttgttat tagataaatt gtctggagat agtcagacag tagtaatgaa atttaaagca
     4441 gataaaccaa actctcttca agctttgttt ggcctatcta atagtaaagc aggctttaaa
     4501 aataattact tttcaatttt catgagagat tctggtgaga taggtgtaga aataagagac
     4561 gcccaaaagg gaataaatta tttattttct agaccagctt cattatgggg aaagcataaa
     4621 ggacaggcag ttgaaaatac actagtattt gtatctgatt ctaaagataa aacatacaca
     4681 atgtatgtta atggaataga agtgttctct gaaacagttg atacattttt gccaatttca
     4741 aatataaatg gtatagataa ggcaacacta ggagctgtta atcgtgaagg taaggaacat
     4801 tacctcgcaa aaggaagtat tgatgaaatc agtctattta acaaagcaat tagtgatcag
     4861 gaagtttcaa atattccctt gtcaaatcca tttcagttaa ttttccaatc aggagattct
     4921 actcaagcta actattttag aataccgaca ctatatacat taagtagcgg aagagttcta
     4981 tcaagtattg atgcacgtta tggtgggact catgattcta aaagtaagat taatattgcc
     5041 acttcttata gtgatgataa tgggaaaacg tggagtgagc caatttttgc tatgaagttt
     5101 aatgactatg aggagcagtt agtttactgg ccacgagata ataaattaaa gaatagtcaa
     5161 attagtggaa gtgcttcatt catagattca tccattgttg aagataaaaa atctgggaaa
     5221 acgatattac tagctgatgt tatgcctgcg ggtattggaa ataataatgc aaataaagcc
     5281 gactcaggtt ttaaagaaat aaatggtcat tattatttaa aactaaagaa gaatggagat
     5341 aacgatttcc gttatacagt tagagaaaat ggtgtcgttt atgatgaaac aactaataaa
     5401 cctacaaatt atactataaa tgataagtat gaagttttgg agggaggaaa gtctttaaca
     5461 gtcgaacaat attcggttga ttttgatagt ggctctttaa gagaaaaaca taatggaaaa
     5521 caggtcccta tgaatgtttt ctacaaagat tcgttattta aagtgactcc tactaattat
     5581 gtagcaatga caactagtca gaatagagga gagagttggg aacaatttaa gttgttgcct
     5641 ccgttcttag gagaaaaaca taatggaact tacttatgtc ccggacaagg tttagcatta
     5701 aaatcaagta acagattgat ttttgcaaca tatactagtg gagaactaac ctatctcatt
     5761 tctgatgata gtggtcaaac atggaagaaa tcctcagctt caattccgtt taaaaatgca
     5821 acagcagaag cacaaatggt tgaactgaga gatggtgtga ttagaacatt ctttagaacc
     5881 actacaggta agatagctta tatgactagt agagattctg gagaaacatg gtcggaagtt
     5941 tcgtatattg atggaatcca acaaacttca tatggcacac aagtatctgc aattaaatac
     6001 tctcaattaa ttgatggaaa agaagcagtc attttgagta caccaaattc tagaagtggc
     6061 cgtaagggag gtcaattagt tgtcggttta gtcaataaag aagatgatag tattgattgg
     6121 aaataccact atgatattga tttgccttcg tatggttatg cctattctgc gattacagaa
     6181 ttgccaaatc atcacatagg tgtactgttt gaaaaatatg attcgtggtc gagaaatgaa
     6241 ttgcatttaa gcaatgtagt tcagtatata gatttggaaa ttaatgattt aacaaaataa
     6301 aggagaaaaa catggttaaa tacggtgttg ttggagcagg gtattttgga gctgaattgg
     6361 ctcgctacat gcaaaagaat gatggagcag agattactct tctctatgat ccagataatg
     6421 cagaggcgat tgcagaagaa ttgggagcaa aagtagcaag ttccttagat gagttggttt
     6481 ctagcgatga agtagattgt gttatcgtcg caactccaaa taatcttcat aaggaaccgg
     6541 ttattaaggc tgcacagcat ggtaaaaatg ttttctgtga aaaaccaatt gcgctttctt
     6601 atcaagattg tcgcgagatg gtagatgcgt gtaaagaaaa caatgtaacc tttatggcag
     6661 gacatattat gaatttcttt aatggtgttc atcatgcaaa agaactcatt aatcaaggag
     6721 ttatcggaga cgttctatat tgtcatacag ctcgtaatgg ttgggaagaa caacaaccgt
     6781 cagtatcatg gaaaaaaatt cgtgaaaaat caggtggtca cttgtatcac cacatccatg
     6841 aattggattg cgttcaattc cttatggggg gcatgcctga aactgtaacc atgacaggtg
     6901 gaaatgtggc ccatgaaggt gaacatttcg gtgatgaaga tgatatgatt tttgtcaata
     6961 tggaattttc taataagcgt tttgctttgt tagaatgggg ttcagcttat cgttggggtg
     7021 aacattatgt cttaatccaa ggaagcaaag gtgccatccg cttagactta ttcaactgta
     7081 aaggaactct taagctagat gggcaagaaa gctatttctt gattcacgaa tcgcaagaag
     7141 aagatgatga tcggactcgt atctatcata gtacagagat ggatggagca attgcttatg
     7201 gtaaaccagg taaacgtact ccattatggc tatcatctgt cattgataaa gaaatgcgct
     7261 atctgcatga gattatggaa ggagctccag tatcagaaga atttgcaaaa cttttgacag
     7321 gtgaagctgc cctagaagca attgctactg cagatgcttg tacccagtct atgtttgaag
     7381 atcgcaaagt aaaattgtca gaaattgtaa aataaatttt ggtattctcc tatttatagg
     7441 tcgacttgct cctctgaaag tacttttaga ggagctgttt gactttgcta gtttttgaaa
     7501 ctgaaatcta ttatactaca aactattgaa agcgttttaa ttttaaggta taataatctc
     7561 atagaaataa agaaaaggag gaaagaggat gccacagatt agcaaagaag ccttgattga
     7621 gcaaatcaaa gatggaatca tcgtttcttg tcaggctctt cctcatgaac cgctttatac
     7681 agaagcggga ggggtgattc ccttgctggt caaagcggct gagcaaggtg gagcagtcgg
     7741 tatccgagca aacagtgttc gcgatatcaa ggaaattaag gaggtcacta aacttccaat
     7801 cattgggatt atcaaacgtg attatccacc tcaggaaccc ttcatcacgg ctactatgaa
     7861 agaagttgat gaattggcag aactggacat cgaggtgatt gctctggatt gtaccaagcg
     7921 tgaacgctac gatggtttgg aaattcaaga gttcattcgt caggttaagg agaaatatcc
     7981 taatcagctt ttgatggctg atactagtat cttcgaagaa gggctagcag ctgtagaagc
     8041 aggaattgac tttgtcggaa caaccttatc aggctacaca tcctacagtc caaaagtaga
     8101 cggtccagat tttgaattga ttaagaaact ctgtgatgcc ggtgtagatg tcattgcaga
     8161 aggaaaaatt catacaccag aacaagccaa acaaatcctt gaatatggag tgcgaggcat
     8221 cgttgttggt ggcgccatta ctagaccaaa agagattaca gaacgcttcg ttgctagtct
     8281 taaataagat gtgaggggga gttttatgtt taaagtttta caaaaagttg gaaaagcttt
     8341 tatgttacct atagctatac ttcctgcagc aggtctactt ttggggattg gtggtgcact
     8401 ttcaaaccca accacgatag caacttatcc aatactagac aatagtattt ttcaatcaat
     8461 attccaagta atgagctctg caggagaggt tgtattcagt aatttgtcac tacttctctg
     8521 tgtgggatta tgtattggct tagcgaaacg agataaagga accgctgcgt tagcaggagt
     8581 aactggttac ttagttatga ctgcaacgat caaagctttg gtaaaacttt ttatggcaga
     8641 aggatctgca attgatactg gagttattgg agcattagtt gtcggaatag ttgccgtata
     8701 tttgcacaac cgatataaca atattcaatt accttccgct ttaggattct ttggaggttc
     8761 acgcttcgtt cctattgtta catcgttctc ttctatcttg attggctttg tcttctttgt
     8821 tatttggcca cctttccaac aacttcttgt ttctacaggt ggatatattt ctcaggcggg
     8881 tccaattgga acttttctat atggattttt aatgagactt tctggagcag taggcttaca
     8941 tcatataatt taccctatgt tttggtatac tgaacttggt ggtgttgaaa ctgttgcagg
     9001 acaaacagtg gttggagctc aaaaaatatt ttttgctcaa ttagccgatt tggcccattc
     9061 tggattattt acagaaggaa caaggttttt tgcaggtcgt ttctcaacaa tgatgttcgg
     9121 tttaccggct gcctgtttag cgatgtacca tagtgttcct aaaaatcgtc gtaaaaaata
     9181 cgcgggtttg ttttttggag ttgctttaac atcttttatt accggtatta cagaaccaat
     9241 tgaatttatg tttctattcg tcagtccggt tctatatgtt gttcacgcat tccttgatgg
     9301 tgttagcttc tttattgcag acgtcttaaa tatttcaata ggaaacacat tttcaggagg
     9361 tgtaatcgat ttcacattat ttggaatttt gcaggggaac gctaagacga attgggttct
     9421 tcagattcca tttggactta tttggagtgt tttgtattat attattttta gatggttcat
     9481 tactcaattc aacgttctaa cgccaggacg aggagaagaa gtagattcta aagaaatttc
     9541 tgaatccgca gattcaactt caaatactgc agattattta aaacaggata gcctacaaat
     9601 tatcagagcc ttgggtggat caaataatat agaagatgta gatgcttgtg tgacacgttt
     9661 acgtgtagct gtaaaagaag ttaatcaagt tgataaagca cttttaaaac aaattggtgc
     9721 agttgatgtc ttagaagtga agggtggcat tcaagcaatc tatggagcaa aagcaatctt
     9781 atataaaaat agtattaatg aaattttagg tgtagatgat taagtactta ctgacttaat
     9841 aaaaaacaga ggagagtgat ggatgagtag gatgaaatga aatcgcatac aagaaataaa
     9901 gaactcatta tccaagttgg atacgcttat tacataggag aatacaaatg aaatttagaa
     9961 aattagcttg tacagtactt gcgggtgctg cggttcttgg tcttgctgct tgtggcaatt
    10021 ctggcggaag taaagatgct gccaaatcag gtggtgacgg tgccaaaaca gaaatcactt
    10081 ggtgggcatt cccagtattt acccaagaaa aaactggtga cggtgttgga acttatgaaa
    10141 aatcaatcat cgaagcgttt gaaaaagcaa acccagatat aaaagtgaaa ttggaaacca
    10201 tcgacttcaa gtcaggtcct gaaaaaatca caacagccat cgaagcagga acagctccag
    10261 acgtactctt tgatgcacca ggacgtatca tccaatacgg taaaaacggt aaattggctg
    10321 agttgaatga cctcttcaca gatgaatttg ttaaagatgt caacaatgaa aacatcgtac
    10381 aagcaagtaa agctggagac aaggcttata tgtatccgat tagttctgcc ccattctaca
    10441 tggcaatgaa caagaaaatg ttagaagatg ctggagtagc aaaccttgta aaagaaggtt
    10501 ggacaactga tgattttgaa aaagtattga aagcacttaa agacaagggt tacacaccag
    10561 gttcattgtt cagttctggt caagggggag accaaggaac acgtgccttt atctctaacc
    10621 tttatagcgg ttctgtaaca gatgaaaaag ttagcaaata tacaactgat gatcctaaat
    10681 tcgtcaaagg tcttgaaaaa gcaactagct ggattaaaga caatttgatc aataatggtt
    10741 cacaatttga cggtggggca gatatccaaa actttgccaa cggtcaaaca tcttacacaa
    10801 tcctttgggc accagctcaa aatggtatcc aagctaaact tttagaagca agtaaggtag
    10861 aagtggtaga agtaccattc ccatcagacg aaggtaagcc agctcttgaa taccttgtaa
    10921 acggatttgc agtattcaac aataaagacg acaagaaagt cgctgcatct aagaaattca
    10981 tccagtttat cgcagatgac aaagagtggg gacctaaaga cgtagttcgt acaggtgctt
    11041 tcccagtccg tacttcattt ggaaaacttt atgaagacaa acgcatggaa acaatcagcg
    11101 gctggactca atactactca ccatactaca acactattga tggttttgct gaaatgagaa
    11161 cactttggtt cccaatgttg caatctgtat caaatggtga cgaaaaacca gcggatgctt
    11221 tgaaagcctt cactgaaaaa gcaaacgaaa caatcaaaaa agctatgaaa caatagtcct
    11281 tagttattct ataaaaagta gttttttaaa gaacctaaga gtgtataccc ccttttccct
    11341 ctacacagat agtgtaagaa aagggggctt ttgtttaaaa tgtaagaaac tgtcacgaaa
    11401 ttaaaatgaa gttcttacat aagcgaatca taaaaaattt cattttgatt ttaaaacagt
    11461 tcaagaaagt caaaaaatta ttctatttga aagagaggtg ccgactgtga aagtcaataa
    11521 aatccgtatg cgggaaacag tgatttccta cgctttccta gcaccagtat tattcttctt
    11581 tgtcatcttt gtgttggctc cgatggtgat gggcttcatt acaagtttct ttaactactc
    11641 aatgactaaa tttgagtttg taggcttgga taactatatc cgtatgttta aagatcctgt
    11701 ctttacaaaa tctctgatta acacagttat tttggttatt ggatctgtac cagttgttgt
    11761 tctattctca ctctttgtag catctcagac ctatcatcaa aatgtcattg ccagatcctt
    11821 ctaccgtttc gtcttcttcc ttcctgttgt aacgggtagt gttgccgtga cagttgtttg
    11881 gaaatggatt tatgacccac tatcagggat tctaaacttt gtccttaagt caagccacat
    11941 catcagccaa aacatttctt ggttgggaga taaaaactgg gcattgatgg cgattatgat
    12001 tattctcttg accacttcag ttggtcagcc catcatcctt tatatcgctg ccatggggaa
    12061 tattgacaat tcactggttg aagcggcgcg tgttgatggt gcaactgagt ttcaagtttt
    12121 ctggaagatt aaatggccaa gccttcttcc aacaactctt tatattgcaa tcatcacaac
    12181 aattaactca ttccagtgtt tcgccttgat tcagcttttg acatctggtg gtccaaacta
    12241 ctcaacaagt accttgatgt actaccttta cgaaaaagcc ttccaattga cagaatacgg
    12301 ctatgccaac acaattggtg tcttcttggc agtcatgatt gctatcgtaa gctttgttca
    12361 atttaaagta cttggaaacg acgtagaata ctaaagaaag gagacagcta tgcaatctac
    12421 agaaaaaaaa ccattaacag cctttactgt tatttcaaca atcattttgc tcttgttgac
    12481 tgtgctgttc atctttccat tctactggat tttgacaggg gcattcaaat cacaacctga
    12541 tacaattgtt attcctcctc agtggttccc taaaatgcca accatggaaa acttccaaca
    12601 actcatggtg cagaaccctg ccttgcaatg gatgtggaac tcagtattta tctcattggt
    12661 aaccatgttc ttagtctgtg caacctcatc tctagcaggt tatgtattgg ctaaaaaacg
    12721 tttctatggt caacgcatcc tatttgctat ctttatcgct gctatggcgc ttccaaaaca
    12781 agttgtcctt gtaccattgg tacgtattgt caacttcatg ggaatccacg atactctctg
    12841 ggcagttatc ttgcctttga ttggatggcc attcggtgtc ttcctcatga aacagttcag
    12901 tgaaaatatt cctacagagt tgcttgaatc agctaaaatc gacggttgtg gtgagattcg
    12961 taccttctgg agtgtagcct tcccgattgt gaaaccaggg tttgcagccc ttgcaatctt
    13021 taccttcatc aatacttgga atgactactt catgcaattg gtaatgttga cttcacgtaa
    13081 caatttgacc atctcacttg gggttgcgac catgcaggct gaaatggcaa ccaactatgg
    13141 tttgattatg gcaggagctg cccttgctgc tgttccaatc gtcacagtct tccttgtctt
    13201 ccaaaaatcc ttcacacagg gtattactat gggagcggtc aaaggataat actctgcgaa
    13261 aatctcttca aactacgtca gcttcacctt gccatactta agtattgcct gcggttagct
    13321 tcctagtttg ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa
    13381 gtatatttta tagatttaga gaatatagag gttataagtg tctacaaaat ggagggtatg
    13441 cagttacttt atgaagtttt gtcagacact tataaactta agaatggttt tagttaacta
    13501 tcagaaacga aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag
    13561 ggattcatcc taatttagac aaggctatcg actatctcta ccaacatcgt aaggattctt
    13621 tcgaattagg aaagtatgat attgatggag ataaagtctt tctagttgtt caggaaaatg
    13681 tcctcaatca agctgaaaat gatcaatttg agtatcataa gaactatgca gatttgcatt
    13741 tgctggtaga aggacatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag
    13801 cattcgacga agcgagtgac attggctttg ttcattgtca tgaacactac ccactcttgt
    13861 tgggttatca caattttgcg attttcttcc caggtgagcc acatcagcca aatggttatg
    13921 caggcatgga agaaaaggtt cgaaaatatc tctttaaaat tttgattgat taaaaatagg
    13981 atgaattgtt tttttgtaaa gctttgataa tactctacca tgaaattgat ctttgtgagg
    14041 tagagaaatg agaataaaat atttaaaaat tggtatcttc taagtatgct gcaagagcta
    14101 gtttcttaga tggacagggg attacagttg atgagatggc ttggataatt aggggcattg
    14161 tgaatgcatt gattggtaga tacataaaat taggtactta tgcggctaag tatggtatta
    14221 gtatggcacg ctcgatctta agtagggtag ctgcaactgc agcagcaaga gtaggattac
    14281 tgaccaagat ttctggatgg attttacgag tagctgtgaa tgtagctgat gtatatggta
    14341 attttgccaa caatattgct gcagcttggg atgcatatga taaaattcct aacaatggtc
    14401 gtataaactt ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag
    14461 cttggacagt gcttgcaatg ataattcgtg gagggctaga tggatttgat aggcatactt
    14521 ggagtactat tttaattgct tcgctgttcg gggtatatga ttatatgtcc atagataaaa
    14581 gtagaaaaaa gtccaaaaga aaaaagaaaa aatagatttg ttcatggtag ggacttatga
    14641 aagttttact gacaaaaaag aaaacagttt acaaagaaaa atgatggagg agcaaacatg
    14701 gcacaaaaag gagtaagcct tatcaaggca gcatttgata cagataactt tctcatgcgt
    14761 tttagtgaga aagtcttgga catcgtgaca gccaatcttc tttttgtcgt ctcttgtttg
    14821 cccatcgtga cgattggagt ggctaaaatc agcctctacg agaccatgtt cgaagttaag
    14881 aagagcagac gggtgcctgt ttttaaaatc tatctaagat ctttcaagca aaatctgaaa
    14941 ctaggtcttc agctgggttt aatggagtta ggaattgtgt ttcttaccct ttcagatctc
    15001 tatcttttct ggggtcaaac agctctgccc ttccaattgc tgaaagccat ttgtttaggt
    15061 attctgattt ttcttactat cgtgatgctg gctagttacc ctatcgcggc acgttatgac
    15121 ctatcttgga aagaaattct tcaaaaagga ttgatgttgg ctagttttaa ctttccttgg
    15181 ttcttcctca tgttagccat tcttgtcctc attgtgatgg ttctttatct gtccgccttc
    15241 agtctactct taggtggctc agtcttccta ctttttgggt ttggactatt ggtctttatc
    15301 cagactggat tgatggagaa aattttcgca aaataccaat aggagcttta tttctgaaac
    15361 tactttcaaa ggctccaaac gctattctat aagcgagaaa ctaaaatcta agtgtctata
    15421 agatattgaa agccttttcg gtaaagtgta tactaaagaa gtaaagaaaa atctgcttta
    15481 gcagaaaata aaaataatag gagaaaatct atgtcagatt tgaaaaaata cgaaggtgtc
    15541 attccagcct tctacgcatg ttatgatgat caaggagaag taagcccaga acgtacgcgt
    15601 gccttggttc aatacttcat tgataaaggt gttcaaggtc tttatgtcaa tggttcttct
    15661 ggtgaatgta tctaccaaag cgttgaagat cgcaagttga ttttggaaga agtcatggcg
    15721 gtagccaaag gtaaattgac cattattgcc catgttgctt gcaataatac taaagatagt
    15781 atggaacttg ctcgccatgc tgaaagcttg ggagtagatg ctattgcaac gattccacca
    15841 atttatttcc gcttgccaga atactcagtt gccaaatact ggaacgatat cagttctgca
    15901 gctccaaaca cagactacgt gatttacaac attcctcaat tggcaggggt tgctttgact
    15961 ccaagccttt acacagaaat gttgaaaaat cctcgtgtta tcggtgtgaa gaactcttct
    16021 atgccagttc aagatatcca aacctttgtc agccttggtg gagaagacca tatcgtcttt
    16081 aatggtcctg atgagcagtt cctaggagga cgcctcatgg gggctagggc tggtatcggt
    16141 ggtacttatg gtgctatgcc agaactcttc ttgaaactca atcagttgat tgcggataag
    16201 gacctagaaa cagcgcgtga attgcagtat gctatcaacg caatcattgg taaactcact
    16261 tctgctcatg gaaatatgta cggtgtcatc aaagaagtct tgaaaatcaa tgaaggcttg
    16321 aatattggat ctgttcgttc accattgaca ccagtgactg aagaagatcg tccagttgta
    16381 gaagcggctg ctgccttgat tcgtgaaacc aaggagcgct tcctctaatc taaaaggagg
    16441 tatttatgac atattacgtt gcaattgata tcggtggaac caacatcaag tatggtttgg
    16501 ttgatcaaga ggggcaactt cttgaatcgc atgaaatgcc aactgaggcg cataagggtg
    16561 gacctcatat cttacaaaag accaaagata tcgtagctag ttatttagaa aaaggcccag
    16621 tagcaggtgt tgccatatct tctgctggga tggtggatcc ggataagggt gagattttct
    16681 atgctgggcc gcaaatccct aactacgcag gcacccagtt caaaaaggaa atcgaagaaa
    16741 gctttactat tccttgtgag attgaaaatg atgtcaactg tgcaggtctt gctgaggcag
    16801 tatctggttc aggcaaggga gcaagtgtga cactttgctt gaccattgga accggtatcg
    16861 gtggttgctt gattatggat aggaaagtct tccatggttt tagcaattca gcctgtgaag
    16921 tcgggtatat gcatatgcag gatggagctt ttcaagactt ggcttctaca acagctttag
    16981 tgaaatatgt agctgaagcc catggagaag atgttgatca gtggaatggc cgtagaattt
    17041 tcaaagaagc cactgaagga aacaaaatct gcatggaagg tattgaccgt atggttgact
    17101 atctaggaaa aggtctggca aatatttgct acgttgccaa tccagaagtg gttattcttg
    17161 gtggtggtat catggggcaa gaggctatcc tcaaacctaa gatccgtaca gccttgaaag
    17221 aggctttggt accaagttta gcagaaaaaa cacgattaga atttgcccat caccaaaata
    17281 cagcagggat gttgggtgca tattatcatt ttaagacaaa acaatcctag tttggctcag
    17341 ccaaactagg attttcttac acgtttttgt ctacgatagc cgttgagttt tttattttcc
    17401 cagtagctat taaagatttt ttccttgctt tcgcgattga tttccaaaaa gtaggcataa
    17461 atcaaatcga taaagaagag cataggaagt tgagcggata ttcgttggat ataggagggt
    17521 tggctgtggg tggctacaag aacagtctct gtataggtct ggctatcttt attgggaaca
    17581 cttgtaaaga gtacagtctt tgcccccatc tccttagcat ctaatagact atctaaaata
    17641 gaaggagttg agcctgaaag tgagaagccc agtactagac aattttcatc catgatgctg
    17701 gttgtccagg caaagccgtc ttggtctgtc aaagcttcgc agaccacacc tagtcgcata
    17761 aaacgtaatt tcatttcacg ggcgacgagg ccagaactcc ctgttccaaa gaagtagata
    17821 cgctcagcat cttcgattag ctgggcaatt cgttctagtt ggatttcgtc aatcaagtct
    17881 tgtgtttgtt ccctcatatt gctataactt ctgaggactc gtttggtcag tggactgtgc
    17941 ttggagactt ggttggcttg attttctgcc tgatgttggt attggaaaat aaattctcgg
    18001 tagccagtaa agccacactt tttagcaaag cgggtcaaag cagcttgaga aatatgtaat
    18061 ttttgggtga cttgttgaga agataaatca tctgtaatcg tttcagcttg caaaaaatag
    18121 cgagcgattt cttgttctag gtctgtcatt tcttcaaaat gtgaatcaat gatagttgcg
    18181 atatctggtt tgtccatagg gaaagctcct ttacatgagt catactggaa gactagatca
    18241 gagaatagtc acacttcatt ataacacata atataaggat agataaataa aaacgcatct
    18301 ctgttttaaa aacgaaaaaa tcgaaaaagc ttctctcttt tccataattt tctactcaaa
    18361 ttgtggtaca attaagagta agattttaag ttagaaatga gactgatttg tatgagaaaa
    18421 tttaacagcc attcgattcc gattcggctt aatttattgt tttcaatcgt cattttactc
    18481 tttatgacca ttattggtcg tttgttgtat atgcaggttt tgaacaagga tttttacgaa
    18541 aaaaagctag cttcagctag tcagaccaag attacaagca gttcagcccg tggggaaatt
    18601 tatgatgcta gtggaaaacc tttggtagaa aatacgttaa agcaggttgt ttcctttacg
    18661 cgtagcaata aaatgacggc tacagactta aaagaaacag ctaaaaagtt actgacttat
    18721 gtgagcatca gttctccaaa tttgacagaa cgccagctgg cggattacta tttggctgat
    18781 cctgaaatct ataaaaaaat agtggaagct ctcccaagtg agaaacgctt ggattcagat
    18841 ggcaatcgtc tatccgaatc agaactgtat aacaatgcgg tcgatagtgt acaaacgagt
    18901 caactaaact atacagagga tgaaaagaaa gaaatctatc tttttagtca gttaaatgct
    18961 gttggaaact ttgcgacagg aaccattgcg acagatcctc taaatgattc tcaggtggct
    19021 gttattgcct ctatttcaaa ggagatgcct ggcattagta tttctacttc ttgggataga
    19081 aaggttttgg aaacttccct ttcttctata gttgggagtg tatccagtga aaaagctggt
    19141 ctcccagcgg aagaagcaga agcctatctt aaaaaaggct attctctaaa tgaccgtgta
    19201 ggaacctcct atttggaaaa gcaatatgaa gagaccttac aaggaaaacg ctcggtaaaa
    19261 gaaatccatc tggataaata tggcaatatg gaaagcgtgg atacaattga ggaaggtagt
    19321 aagggaaaca atatcaaact gaccattgat ttggccttcc aagatagcgt ggatgcttta
    19381 ctgaaaagtt atttcaattc tgagctagaa aatggtggag ccaagtattc tgaaggtgtc
    19441 tatgcagtcg cccttaaccc aaaaacaggt gcggttttgt ctatgtcagg gattaaacat
    19501 gacttgaaaa cgggagagtt gacgcctgat tccttgggaa cggtaaccaa tgtctttgtt
    19561 ccaggttcgg ttgtcaaggc ggcgaccatc agctcaggtt gggaaaatgg agtcttgtca
    19621 ggaaaccaga ccttgacaga ccagtccatt gtcttccaag gttcagctcc catcaattct
    19681 tggtatactc aggcttacgg ttcattccct atcacagcgg tccaagctct ggagtattca
    19741 tcaaatacct atatggtcca aacagcctta ggtcttatgg ggcaaaccta tcaacccaat
    19801 atgtttgtcg gcaccagcaa tctagagtct gctatggaga aactgcgttc aacctttggc
    19861 gaatatggct tgggtactgc gacaggaatt gacctaccag atgaatctac tggatttgtt
    19921 cccaaagagt atagctttgc taattacatt actaatgcct ttgggcagtt tgataactat
    19981 acgccgatgc agttggctca gtatgtagca actattgcaa ataatggtgt tcgtgtggct
    20041 cctcgtattg ttgaaggcat ttatggtaat aatgataagg gaggactggg tgacttgatt
    20101 cagcaactgc aaccgacaga gatgaataag gtcaatatat ccgactccga tatgagcatc
    20161 ttgcaccaag gtttttatca ggttgcccat ggtactagtg gattgacaac tggacgtgcc
    20221 ttttcaaatg gtgccttggt atccattagc ggaaaaacag gtacagccga aagctatgtg
    20281 gcagatggtc agcaagcaac caataccaat gcggtggcct atgccccatc tgataatccc
    20341 caaatcgctg tcgcagtggt ctttcctcat aataccaatc taacaaatgg tgtaggacct
    20401 tccattgcgc gtgacattat caatctgtat caaaaatacc atccaatgaa ctagaaagga
    20461 aattatgctt tatccaacac ctattgccaa gttgattgac agttattcta agttaccagg
    20521 tatcgggatt aagacggcta cgcgtctggc cttttatacg attgggatgt ctgctgatga
    20581 tgtcaatgaa tttgcaaaaa atctcctttc tgctaagaga gaattgacat attgttctat
    20641 ttgtggacgt ttgacagacg acgatccttg ttctatctgt actgatccga ctcgtgacca
    20701 gacaacaatt ttagttcttg aggatagtag agatgtggca gccatggaaa atatccaaga
    20761 ataccatgga ctctatcatg tccttcatgg cctcatttct cctatgaatg gtatcagtcc
    20821 ggacgatatc aatctcaaga gccttatgac tcgtcttatg gatagtgagg tttcagaagt
    20881 gattgtggcg actaatgcta cagcggatgg tgaagcgact tccatgtatc tttcacgttt
    20941 gctcaagccg gctggtatca aggttacgcg tctagcacga ggtctcgctg tgggagcgga
    21001 cattgagtat gcggacgaag tgacactctt acgagccatt gaaaatcgga cagagttgta
    21061 agtgtaggca aatttacgaa ctccattcat ttataaaaaa tcaaagaggc tgaaaatcgt
    21121 tcctatcggc ctctttttgt atagtgtgat gagtaggctc aggttcaagt tttaaaaaac
    21181 caagcaaata tgatatacta aagagcgagt attctagtag aattaggaca aataatatga
    21241 aacaaacgat tattctttta tatggtggac ggagtgcgga acgcgaagtc tctgtccttt
    21301 cagctgagag tgtcatgcgt gcggtcgatt acgaccgttt cacagtcaag actttcttta
    21361 tcagtcagtc aggtgacttt atcaaaacac aggaatttag tcatgctccg gggcaagaag
    21421 accgtctcat gaccaatgaa accattgatt gggataagaa agttgcacca agtgctatct
    21481 acgaagaagg tgcagtggtc tttccagtcc ttcacgggcc aatgggagaa gatggctctg
    21541 ttcaaggatt cttggaagtt ttgaaaatgc cttacgttgg ttgcaacatt ttgtcatcaa
    21601 gtcttgccat ggataaaatc acgactaagc gtgttctgga atctgctggt attgcccaag
    21661 ttccttatgt ggctatcgtt gaaggcgatg atgtgactgc taaaatcgct gaagtggaag
    21721 aaaaattggc ttatccagtc ttcactaagc cgtcaaacat ggggtctagt gtcggtattt
    21781 ctaagtctga aaaccaagaa gaactccgtc aagccttaaa acttgccttc cgatatgaca
    21841 gccgtgtctt ggttgagcaa ggagtgaatg cccgtgaaat tgaggttggc ctcttgggta
    21901 actacgatgt caagagcacg ctacctggag aagttgtcaa ggacgttgcc ttttatgact
    21961 acgatgccaa gtatattgat aacaagatta ctatggatat tcctgccaaa atcagtgatg
    22021 atgtggtggc tgtcatgcgt caaaatgcag aaacagcctt ccgtgccatt ggtggccttg
    22081 gtctatctcg ttgcgatttc ttctatacag ataagggaga gatttttctc aacgagctca
    22141 ataccatgcc aggttttacc cagtggtcta tgtacccact actttgggac aatatgggga
    22201 tcagctaccc agaactaatc gaacgtttgg ttgaccttgc caaggaaagc tttgacaagc
    22261 gcgaagcgca tttgatataa aatgaaagag agggtagaag ccagaaccat cactgcacgg
    22321 tgactagagt tctcggactt cagccctttt taaaggagta gaaatgaaat taacaatcca
    22381 tgaaattgcc caagttgttg gagccaaaaa tgatatcagt atctttgagg acacccagtt
    22441 agaaaaagct gagtttgata gtcgtttgat tggaactgga gatttatttg tgccacttaa
    22501 aggtgcgcgt gatggccatg actttattga aacagccttt gaaaatggtg cagcagtaac
    22561 cttgtctgag aaagaggtct caaatcatcc ttacatttta gtagatgatg ttttgacagc
    22621 ctttcaatcc ctagcatcct actatcttga aaaaacgact gttgatgtct ttgctgttac
    22681 aggttcaaat ggcaagacaa cgactaagga tatgttggcg catttactgt caacaagata
    22741 caagacctac aaaacacaag gcaattacaa taatgagatt ggccttcctt acacagttct
    22801 ccacatgcct gaaggaacag aaaagttggt cttggagatg gggcaggacc acttgggaga
    22861 tattcatctc ttgtctgaat tggctcgtcc aaaaacagcc atcgtgacct tggttggaga
    22921 agctcatttg gcctttttca aagatcgttc tgagattgct aaaggaaaaa tgcaaattgc
    22981 agacggaatg gcttcaggtt ccttgttttt agcgccggct gaccctatcg tagaggacta
    23041 tttgccaact gataaaaagg tggttcgttt tggtcaagga gcagagctgg aaattactga
    23101 cttggttgag agcaaagata gtctgacctt caaggccaat ttcttagagc aagtccttga
    23161 tttgccagta actggcaagt acaatgcgac aaatgctatg attgcatcct atgttgcctt
    23221 gcaagaagga gtttcagagg agcaaattcg tttggccttc caacatcttg aattgacgcg
    23281 taaccgtacc gagtggaaga aagcagtcaa tggagcagat atcctgtcag atgtttacaa
    23341 tgccaatcca actgctatga aactgatttt agagactttc tctgccattc cagccaatga
    23401 aggtggcaag aaaattgcag ttttggcgga tatgaaggag cttggtgacc agtctgttca
    23461 acttcataat cagatgattt tgagcctctc cccagatgtg cttgatatcg ttattttcta
    23521 tggagaagat attgctcagt tggctcaatt ggccagtcaa atgtttccaa tcggccacgt
    23581 ttactacttc aagaaaacag aagaccagga tcaatttgaa gacctagtca agcaggttaa
    23641 ggaaagcctt ggagcctatg accaaatctt gctaaaaggt tctaactcta tgaatctagc
    23701 caaattggta gaaagtttag aaaatgaagc caagtgattt tgttaagtat ctgcaaagaa
    23761 tgattgccct tacagatact ggcttaacct ttacaaaaga tccttttgac cgtgagcgct
    23821 acgaggactt gcgaagtctg ttatctgaaa tgttgaatca gggatcagac ctggatgtag
    23881 aagaagtagc agaagtcttg aaaccaactt cagcttatgc gactccctta atggacgtcc
    23941 gtgcttggat tgttgaggat gagaagattt gtctggttag gggacaagga gaggatagtt
    24001 gggctttgcc aggtggcttt ggtgaagtcg gctattctcc aactgaaaat attctcaagg
    24061 aaattgaaga agaaaccggt tttaaagcca aagttgaaag actgctagct gtttttgata
    24121 ccaatcgttt ccaactacag agcaaacaat atgcaaagtt tgtttttgaa tgtaagcttc
    24181 tcgatggaca attccaagaa aatcaagaaa tcgctgacct tcaatttttt gcaattgacc
    24241 aactgccgaa tttatctgaa aaacgcatta ccaaggagca aatcgagatt ctttggcagg
    24301 tttatcaagg tcagagggag caatatcttg actaagaaga tgattatcgt atttctaaat
    24361 tcatttttct taagtagcat ggtataataa aatgcaggaa aattttgaat catgaggaag
    24421 actagatgaa tttatgggat attttcttta cgactcaggc aaccgagccg cccaaatttg
    24481 accttttttg gtatgttagc ctatttacgc tcttagcctt aaccttttat acagcccatc
    24541 gctatcgtga aaagaaggtt taccaacgat ttttccaaat cttgcagact gttcagttaa
    24601 tccttcttta tggttggtac tgggtcaatc atatgccact gtcagaaagc ctaccctttt
    24661 accattgccg tatggctatg tttgtggtac tcttgcttcc tggtcagtcc aaatataaac
    24721 aatactttgc attattggga acatttggga cattagcagc ctttgtttat ccagtgccag
    24781 atgcttaccc ttttccacat atcaccattc tatcctttat ctttggtcat ttagcactct
    24841 tggggaactc tctagtttat ctattgagac agtataatgc gcgattgctg gatgtgaagg
    24901 gaatttttct catgaccttt gccctaaatg ccttgatttt tgtggtcaat ttggtgacag
    24961 gtggcgatta cggatttttg acaaaaccgc cattggttgg ggatcacggt ctagtagcta
    25021 attatttact tgtttcaatt gtgctggtag ctactatcag tttgactaag aaaatcttag
    25081 aattcttttt agctcaagaa gcagaaaaaa tgattgcaaa ggaagcttaa cacagagctt
    25141 tcttttttgc tcttagagag tttttacaag cagcttataa aataagaatt tctgaataga
    25201 caaactcaaa aaatggctgg gaaatttagg aaaaaagcaa gcacgattaa attttttgtg
    25261 ttataatatt ttgtgaatag ctatgcctat gtttagctat ggaataatac gaagtgcgaa
    25321 acttggaaga tagagaggaa gcgatgtaat ggctagagaa ggctttttta caggtctaga
    25381 tattggaaca agctctgtca aggtgcttgt ggccgagcag agaaatggtg aattaaatgt
    25441 aattggcgtg agtaatgcca aaagtaaagg tgtaaaggat ggaattattg ttgatattga
    25501 tgcagcagca actgctatca agtcagccat ttcccaagcg gaagaaaagg caggcatttc
    25561 gattaaatca gtgaatgtcg gcttgcctgg taatcttttg caggtagaac caactcaggg
    25621 gatgattcca gtaacatctg atactaagga aattacggat caagatgttg aaaatgttgt
    25681 caaatcagct ttgacaaaga gtatgacacc tgaccgtgaa gtcattacct ttattcctga
    25741 agaatttatt gtggatggtt tccaagggat tcgtgaccca cgtggcatga tgggggttcg
    25801 ccttgaaatg cgtggtttgc tttatacagg acctcgtact atcttgcaca atttgcgtaa
    25861 gacggttgag cgtgcaggtg ttcaggttga aaatgttatc atttcaccac tagcaatggt
    25921 tcagtctgtt ttgaacgaag gggaacgtga atttggtgct acagtgattg atatgggggc
    25981 aggtcaaacg actgtcgcta caatccgtaa tcaagaactc cagttcacac atattctcca
    26041 agaaggtgga gattatgtaa ctaaagatat ctccaaggtt ttgaaaacct ctcgcaaatt
    26101 agcggaaggc ttgaaactga attacgggga agcctatccg cctcttgcaa gcaaagaaac
    26161 cttccaagta gaggttattg gagaagtaga agcagtcgaa gtgacggaag cctacttgtc
    26221 agaaattatt tctgcacgaa tcaagcacat ccttgaacaa atcaagcaag aattagatag
    26281 aaggcgtcta ttggacctcc ctggtggtat tgtcttaatc ggtgggaatg ccattttacc
    26341 aggtatggtt gagcttgctc aggaagtctt tggcgtccgt gtcaagcttt atgttccaaa
    26401 tcaagttggt atccgtaatc cagcctttgc gcatgtgatt agtttatcag aatttgcggg
    26461 tcaattaaca gaagttaatc ttttggctca gggagcgata aaaggtgaga atgacttaag
    26521 tcatcagcca attagttttg gtgggatgct gcaaaaaaca gctcagtttg tacaatcaac
    26581 gcctgttcaa ccagctcctg ctccagaagt agagccggtg gcgcctacag aaccaatggc
    26641 ggatttccaa caagcttcac aaaataaacc gaaattagca gatcgtttcc gtggattgat
    26701 cggaagcatg tttgacgaat aaagaggaaa aataaattat gacattttca tttgatacag
    26761 ctgctgctca aggggcagtg attaaagtaa ttggtgtcgg tggaggtggt ggcaatgcca
    26821 tcaaccgtat ggtcgacgaa ggtgttacag gcgtagaatt tatcgcagca aacacagatg
    26881 tacaagcatt gagtagtaca aaagctgaga ctgttattca gttgggacct aaattgactc
    26941 gtggtttggg tgcaggaggt caacctgagg ttggtcgtaa agccgctgaa gaaagcgaag
    27001 aaacactgac ggaagctatt agtggtgccg atatggtctt catcactgct ggtatgggag
    27061 gaggctctgg aactggagct gctcctgtta ttgctcgtat cgccaaagat ttaggtgcgc
    27121 ttacagttgg tgttgtaaca cgtccctttg gttttgaagg aagtaagcgt ggacaatttg
    27181 ctgtagaagg aatcaatcaa cttcgtgagc atgtagacac tctattgatt atctcaaaca
    27241 acaatttgct tgaaattgtt gataagaaaa caccgctttt ggaggctctt agcgaagcgg
    27301 ataacgttct tcgtcaaggt gttcaaggga ttaccgattt gattaccaat ccaggattga
    27361 ttaaccttga ctttgccgat gtgaaaacgg taatggcaaa caaagggaat gctcttatgg
    27421 gtattggtat cggtagtgga gaagaacgtg tggtagaagc ggcacgtaag gcaatctatt
    27481 caccacttct tgaaacaact attgacggtg ctgaggatgt tatcgtcaac gttactggtg
    27541 gtcttgactt aaccttgatt gaggcagaag aggcttcaca aattgtgaac caggcagcag
    27601 gtcaaggagt gaacatctgg ctcggtactt caattgatga aagtatgcgt gatgaaattc
    27661 gtgtaacagt tgttgcaacg ggtgttcgtc aagaccgcgt agaaaaggtt gtggctccac
    27721 aagctagatc tgctactaac taccgtgaga cagtgaaacc agctcattca catggctttg
    27781 atcgtcattt tgatatggca gaaacagttg aattgccaaa acaaaatcca cgtcgtttgg
    27841 aaccaactca ggcatctgct tttggtgatt gggatcttcg ccgtgaatcg attgttcgta
    27901 caacagattc agtcgtttct ccagtcgagc gctttgaagc cccaatttca caagatgaag
    27961 atgaattgga tacacctcca tttttcaaaa atcgttaagt aaatgaatgt aaaagaaaat
    28021 acagaacttg tttttcgaga agttgcagag gctagtctga gtgctcatcg agagagtggt
    28081 tcggtctctg tcattgcagt taccaagtat gtagatgtac cgacagcgga agccttgctt
    28141 ccgctaggtg ttcatcatat cggtgaaaat cgtgtagata agtttctgga aaaatatgaa
    28201 gctttaaaag atcgagatgt gacttggcat ttgattggta ccttgcaaag acgtaaggtg
    28261 aaagatgtca ttcaatacgt tgattatttc catgcattgg actcagtaaa gctagcaggg
    28321 gaaattcaaa aaagaagtga ccgagtcatc aagtgtttcc ttcaagtaaa tatttctaaa
    28381 gaagaaagca aacacggttt ttcgagagag gaactgctgg aaatcttgcc agagttagcc
    28441 agactagata agattgaata tgttggttta atgacgatgg caccttttga ggctagcagt
    28501 gagcagttga aagagatttt caaggcggcc caagatttac aaagagaaat tcaagagaaa
    28561 caaattccaa atatgcctat gaccgagtta agtatgggaa tgagtcgtga ttataaagaa
    28621 gcgattcaat tcggttccac ttttgttcgt ataggtacat cattttttaa gtaggagaga
    28681 accatgtctt taaaagatag attcgataga tttatagatt attttacgga ggatgaggat
    28741 tcaagtctcc cttatgaaaa aagagatgag cctgtgttta cttcagtaaa ttcttcacag
    28801 gaaccggctc tcccaatgaa tcaaccttca cagtcggctg ggacaaaaga gaacaatatt
    28861 accagacttc atgcaagaca acaggaattg gcaaatcaga gtcagcgtgc aacggataag
    28921 gtcattatag atgttcgtta tcctagaaaa tatgaggatg caacagaaat tgttgattta
    28981 ttggcaggaa acgaaagtat cttgattgat tttcagtata tgacagaggt gcaggctcgt
    29041 cgttgtttgg actatttgga tggagcttgt catgttttag ctggaaattt gaaaaaggta
    29101 gcttctacca tgtatttgtt gacaccagtg aacgttattg taaatgttga agatatccgt
    29161 ttaccagatg aagatcaaca gggtgagttc ggttttgata tgaagcgaaa tagagtacga
    29221 taatgatttt tttaattcgt atgatttata atgcagtgga tatttactcc ctgattttgg
    29281 tagccttcgc tgtcatgtct tggtttccag gtgcctacga atccagttta ggtcgttgga
    29341 ttgtagcgtt ggtgaaacca gtgcttgctc ccttgcaacg cctgccttta cagatagcgg
    29401 gtcttgattt atctgtttgg gtcgcgattg ttttggttcg atttttagga gaaaacctag
    29461 tgcgttttct ggcgatgata ggatgaataa agggatttat cagcatttct ccatagaaga
    29521 tcgtccattt cttgacaagg gaatggaatg gataaagaag gtagaagata gctatgctcc
    29581 ttttttaact ccttttatca atcctcatca ggagaagcta ttaaagattt tggccaaaac
    29641 ctatggtctt gcttgtagca gtagtgggga attcgtctcg agtgagtatg ttcgagtttt
    29701 attataccca gattatttcc aaccagagtt ttcagatttt gaaatatctc tccaggaaat
    29761 tgtgtattcc aataaatttg aacatttaac gcatgctaag attttaggga cagtcatcaa
    29821 tcaattaggg attgaacgga aactttttgg agatatccta gtagatgaag aacgggcgca
    29881 gattatgatt aatcagcagt ttcttcttct ctttcaagat ggactaaaga aaattggtcg
    29941 tatacctgtt tcgctggagg aacgtccttt caccgagaaa atagataagc tagaacagta
    30001 tcgagaactg aatttatctg tgtctagttt tcgattagat gttcttttat caaatgtttt
    30061 gaaactatct aggaatcaag caaaccagtt gattgaaaag aaacttgtcc aagtaaatta
    30121 tcatgtggta gacaaatcag attacactgt tcaagttgga gacttgatta gtgtgagaaa
    30181 atttggtcgc ttgagattat ttcaagataa gggacaaacg aaaaaagaga agaaaaaaat
    30241 aaccgtccag ttattattaa gtaagtgagg aatagaatgc caattacatc attagaaata
    30301 aaggacaaga cctttggaac tcgattcaga ggttttgatc cagaagaagt cgatgaattt
    30361 ttagatattg tggttcgtga ttacgaagat cttgtgcgtg cgaatcatga taaaaatttg
    30421 cgtattaaga gtttagaaga gcgtttgtct tactttgatg aaataaaaga ttcattgagc
    30481 cagtctgtat tgattgccca ggatacagct gagcgagtga aacaggcggc gcatgagcgt
    30541 tcaaacaata tcattcatca agcagagcaa gatgcgcaac gcttgttgga agaagctaaa
    30601 tataaggcaa acgagattct tcgtcaagca actgataatg ctaagaaagt cgctgttgaa
    30661 acagaagaat tgaagaacaa gagccgtgtc ttccaccaac gtctcaaatc tacaattgag
    30721 agtcagttgg ctattgttga atcttcagat tgggaagata ttctccgtcc aacagctact
    30781 tatcttcaaa ctagtgatga agcctttaaa gaagtggtta gcgaagtact tggagaaccg
    30841 attccagctc caattgaaga agaaccaatt gatatgacac gtcagttctc tcaagcagaa
    30901 atggaagaat tacaagctcg tattgaggta gccgataaag aattgtctga atttgaagct
    30961 cagattaaac aggaagtgga aactccaact cctgtagtga gtcctcaagt tgaagaagag
    31021 cctctgctca tccagttggc ccaatgtatg aagaaccaga agtagctcca gtgcatccga
    31081 caggtccaac accagctaca gaaactgttg attcagcacc aggatttgaa gcaccgcaag
    31141 aatccgttac aattttataa gaaacgatgt gagaacaata tcttatcctt atatttccag
    31201 cgagcaggag atggtgtgag tcctgcattc cctaacgata agattatcct ctcaaaaact
    31261 caagtctgaa gctagtaaga tttgacgttt cccacgttac gggataagag ggagaaagac
    31321 taaatctttt tccgaataaa ggtggtacca cgattttcgt cctttttgga agtcgtggtt
    31381 tttaatttgt tattatttat aaaggagata ccatgaaact caaagatacc cttaatcttg
    31441 ggaaaacagc tttcccaatg cgtgcaggcc ttccgaccaa agagccagtt tggcaaaagg
    31501 aatgggaaga tgcaaaactt taccaacgtc gtcaagaact aaatgaaggg aaaccgcatt
    31561 ttgtcttgca tgatggccct ccatacgcaa acggaaatat ccacgttgga catgccatga
    31621 atcatatctc aaaagatatc atcattcgtt ctaagtctat gtcaggtttt aacgcacctt
    31681 atatcccagg ttgggatact catggtctgc caatcgagca agttttggca aagcaaggtg
    31741 tgaagcgcaa agaaatggac ttggttgagt acttgaaact ctgtcgtgag tacgctcttt
    31801 ctcaagttta taaacaacgt gatgatttca aacgcttggg gatgtcaggt gactgggaaa
    31861 atccatatgt gactttaact ccagactatg aagcagccca aatccgtgtc tttggtgaga
    31921 tggctaataa gggttatatc taccgtggtg ccaagccagt ttactggtca tggtcatctg
    31981 agtcagccct tgccgaagcg gaaattgaat accatgattt ggtttcgact tcactttatt
    32041 atgccaataa ggtaaaagat ggcaaaggta tcctagatac agatacttat atcgtagtct
    32101 ggacaacaac tccatttacc atcacagctt ctcgtggttt gactgttggt gcagatattg
    32161 attacgtttt ggttcaacct gctagtgaaa ctcgtaagtt tgtcgttgct gcagaattgt
    32221 tgactagctt gtctgagaaa tttggctggg ctgatgttca agtgttggca acttaccgtg
    32281 gtcaagaact caaccacatc gtaacagaac acccatggga tacagctgta gatgagttgg
    32341 taatccttgg tgatcacgtt accactgact ctggtacagg tatcgtccat acagcccctg
    32401 gttttggtga ggacgactac aatgttggta ttgctaatgg tcttgaagtc gcagtgactg
    32461 ttgacgaacg cggtatcatg atggcgaatg ctggtcctga gtttgaaggt cagttctacg
    32521 acaaggttgt accaactgtt attgaaaaac ttggtaacct ccttctagcc caagaagaaa
    32581 tctctcactc atacccattt gactggcgta ctaagaaacc aatcatctgg cgtgcagttc
    32641 cacaatggtt tgcctcagtt tcaaaattcc gccaagaaat cttggatgct attgataaag
    32701 ttaaattcca tacagaatgg ggtaaagtac gtctatataa tatgattcgt gaccgtggtg
    32761 actgggttat ctctcgtcaa cgtgcttggg gtgttccact tccaatcttc tatgcagaag
    32821 acggtacagc tatcatgaca gctgagacta ttgaacatgt ggcgcaactc tttgaagtac
    32881 atggttcaag catttggtgg gaacgtgatg ccaaagacct cttaccagaa ggatttacac
    32941 atccaggttc tccaaatggg gagttcaaga aagaaacaga tattatggat gtatggtttg
    33001 actcaggttc atcatggaat ggtgttttgg taaatcgtcc aaatctgact tatccagctg
    33061 acctttacct tgaaggttct gaccaatacc gtggttggtt caactcatca ctcattacat
    33121 ctgttgccaa ccatggcgta gcaccttaca aacaaatctt gtcacaaggt tttacccttg
    33181 atggtaaagg tgagaagatg tctaaatcac ttggaaatac cattgctcca agtgatgttg
    33241 aaaaacaatt tggtgcagaa atcttgcgtc tctgggtaac aagtgttgac tcaagcaatg
    33301 acgtgcgtat ctctatggat attttgagcc aagtttctga aacttaccgt aagattcgta
    33361 acactcttcg tttcttgatt gccaatacat ctgactttaa cccagctcaa gatgtagtcg
    33421 cttacgatga acttcgttca gttgataagt acatgactat tcgctttaac cagcttgtca
    33481 agaccattcg tgatgcctat gcggactttg aattcttgac aatctacaag gccttggtga
    33541 actttatcaa cgttgacttg tcagccttct accttgattt tgccaaagat gttgtttaca
    33601 ttgaaggtgc caaatcattg gaacgccgtc aaatgcagac tgttttctat gacattcttg
    33661 tcaaaatcac caaactcttg acaccaatcc ttcctcacac tgcggaagaa atctggtcat
    33721 atcttgagtt tgaagctgaa gacttcgttc aattgtcaga attgccagaa gctcaaactt
    33781 ttgctaatca agaagaagtc ttggatacat gggcagcctt catggacttc cgtggacaag
    33841 ctcaaaaagc cttggaagaa gctcgtaatg caaaagttat cgggaaatcg cttgaagcac
    33901 acttgacagt ttatccaaat gaagttgtga aaactctact cgaagcagta aacagcaatg
    33961 tggctcaact tttgatcgtg tcagacttga ccatcgcaga agggccagct ccagaagctg
    34021 ctgttagctt cgaagatgta gccttcacag ttgaacgcgc tgcaggtcaa gtatgtgacc
    34081 gttgccgtcg tatcgaccca acaacagcag aacgcagcta ccaggcagtc atctgtgacc
    34141 actgtgcaag catcgtagaa gaaaactttg cggaagcagt cgcagaagga tttgaagaga
    34201 aataaggttg aaaagtctag gcaaaattca atttgagaag aaaagacaac taattttata
    34261 gtctattaaa cgcattgtat cacgtttttg aatacctgat atgatgcgtt ttttatttat
    34321 tttaaaaatt tgcgaggtat gactttttat actcaacaag aatcaaagag aaacttagca
    34381 agctaacagt agtaagataa aataggaatt tgatatt
//
LOCUS       DAVMAH010000020        34041 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVMAH010000020 DAVMAH010000000
VERSION     DAVMAH010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34041
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.020"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(223..585)
                     /locus_tag="VYO94_000891"
     CDS             complement(223..585)
                     /locus_tag="VYO94_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV1759549.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            593..673
                     /locus_tag="VYO94_000892"
                     /pseudo
     CDS             593..673
                     /locus_tag="VYO94_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(1101..1238)
                     /locus_tag="VYO94_000893"
                     /pseudo
     CDS             complement(1101..1238)
                     /locus_tag="VYO94_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1616..2305)
                     /gene="rplA"
                     /locus_tag="VYO94_000894"
     CDS             complement(1616..2305)
                     /gene="rplA"
                     /locus_tag="VYO94_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV1759550.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2513..2938)
                     /gene="rplK"
                     /locus_tag="VYO94_000895"
     CDS             complement(2513..2938)
                     /gene="rplK"
                     /locus_tag="VYO94_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV1759551.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            3070..3207
                     /locus_tag="VYO94_000896"
     CDS             3070..3207
                     /locus_tag="VYO94_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759552.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            complement(3247..3963)
                     /locus_tag="VYO94_000897"
     CDS             complement(3247..3963)
                     /locus_tag="VYO94_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV1759553.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3966..4436)
                     /locus_tag="VYO94_000898"
     CDS             complement(3966..4436)
                     /locus_tag="VYO94_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1759554.1"
                     /translation="MCLICQRIELIKKGENPYFVRELETGYLVIGDHQYFVGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSLIQEAVAKAFTAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(4438..5475)
                     /locus_tag="VYO94_000899"
     CDS             complement(4438..5475)
                     /locus_tag="VYO94_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV1759555.1"
                     /translation="MNQTVNYIKELTAIASPTGFTREISEYLVHTLEELGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGKTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDEKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIDLPMTTHFAFSVFEE
                     VGHGANSNIPEEVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSALVD"
     gene            complement(5573..6898)
                     /gene="brnQ"
                     /locus_tag="VYO94_000900"
     CDS             complement(5573..6898)
                     /gene="brnQ"
                     /locus_tag="VYO94_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV1759556.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(7069..7161)
                     /locus_tag="VYO94_000901"
     CDS             complement(7069..7161)
                     /locus_tag="VYO94_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1759557.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(7204..7356)
                     /locus_tag="VYO94_000902"
     CDS             complement(7204..7356)
                     /locus_tag="VYO94_000902"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1759558.1"
                     /translation="MKEIAFDAFYQLYQNDQFSLVDVREVDEFAALHLEGAYNLPLSQ
                     LADSYD"
     gene            complement(7516..8094)
                     /locus_tag="VYO94_000903"
     CDS             complement(7516..8094)
                     /locus_tag="VYO94_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV1759559.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(8148..9548)
                     /gene="pepV"
                     /locus_tag="VYO94_000904"
     CDS             complement(8148..9548)
                     /gene="pepV"
                     /locus_tag="VYO94_000904"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV1759560.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9561..10166)
                     /locus_tag="VYO94_000905"
     CDS             complement(9561..10166)
                     /locus_tag="VYO94_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV1759561.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            10337..11137
                     /locus_tag="VYO94_000906"
     CDS             10337..11137
                     /locus_tag="VYO94_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1759562.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIVFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11319..12152)
                     /locus_tag="VYO94_000907"
     CDS             complement(11319..12152)
                     /locus_tag="VYO94_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1759563.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQGHNLELLASLIEKHGYVEDVKDFFDF
                     L"
     gene            complement(12142..13986)
                     /gene="uvrC"
                     /locus_tag="VYO94_000908"
     CDS             complement(12142..13986)
                     /gene="uvrC"
                     /locus_tag="VYO94_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV1759564.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(14026..14727)
                     /locus_tag="VYO94_000909"
     CDS             complement(14026..14727)
                     /locus_tag="VYO94_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV1759565.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14806..16038)
                     /gene="murN"
                     /locus_tag="VYO94_000910"
     CDS             complement(14806..16038)
                     /gene="murN"
                     /locus_tag="VYO94_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV1759566.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEEKLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(16043..17263)
                     /gene="murM"
                     /locus_tag="VYO94_000911"
     CDS             complement(16043..17263)
                     /gene="murM"
                     /locus_tag="VYO94_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV1759567.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17375..18154)
                     /locus_tag="VYO94_000912"
     CDS             complement(17375..18154)
                     /locus_tag="VYO94_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1759568.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYMALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(18223..19884)
                     /locus_tag="VYO94_000913"
     CDS             complement(18223..19884)
                     /locus_tag="VYO94_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1759569.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(20059..22281)
                     /gene="recJ"
                     /locus_tag="VYO94_000914"
     CDS             complement(20059..22281)
                     /gene="recJ"
                     /locus_tag="VYO94_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV1759570.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQNQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNFAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22557..23315
                     /locus_tag="VYO94_000915"
     CDS             22557..23315
                     /locus_tag="VYO94_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1759571.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHLNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            23326..24120
                     /locus_tag="VYO94_000916"
     CDS             23326..24120
                     /locus_tag="VYO94_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1759572.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKIVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLTFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSD
                     YGIVTKKSNTELNDYLDTLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            24133..24810
                     /locus_tag="VYO94_000917"
     CDS             24133..24810
                     /locus_tag="VYO94_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1759573.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24820..25479
                     /locus_tag="VYO94_000918"
     CDS             24820..25479
                     /locus_tag="VYO94_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1759574.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKIKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25774..26964
                     /locus_tag="VYO94_000919"
     CDS             25774..26964
                     /locus_tag="VYO94_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV1759575.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(27285..28166)
                     /locus_tag="VYO94_000920"
     CDS             complement(27285..28166)
                     /locus_tag="VYO94_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV1759576.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(28307..29635)
                     /gene="vncS"
                     /locus_tag="VYO94_000921"
     CDS             complement(28307..29635)
                     /gene="vncS"
                     /locus_tag="VYO94_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV1759577.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMYLDAQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVAQD"
     gene            complement(29632..30288)
                     /gene="vncR"
                     /locus_tag="VYO94_000922"
     CDS             complement(29632..30288)
                     /gene="vncR"
                     /locus_tag="VYO94_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV1759578.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(30337..30420)
                     /gene="pep27"
                     /locus_tag="VYO94_000923"
     CDS             complement(30337..30420)
                     /gene="pep27"
                     /locus_tag="VYO94_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV1759579.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(30600..31979)
                     /gene="vex3"
                     /locus_tag="VYO94_000924"
     CDS             complement(30600..31979)
                     /gene="vex3"
                     /locus_tag="VYO94_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV1759580.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFIIESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(32031..32678)
                     /gene="vex2"
                     /locus_tag="VYO94_000925"
     CDS             complement(32031..32678)
                     /gene="vex2"
                     /locus_tag="VYO94_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV1759581.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32691..33968)
                     /locus_tag="VYO94_000926"
     CDS             complement(32691..33968)
                     /locus_tag="VYO94_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1759582.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9697 a         7760 c         6331 g        10253 t
ORIGIN      
        1 taaactaacc tcctcattat tagcaaggat tctactgatt ataacctaat tcttagacta
       61 cttcaagact aactgtccaa taataatcta cagataaatc atccactctt aataaaattt
      121 tattcaatcc atctactcat tcccaaaagg ttgctgtata atgcaagaca tttttcttac
      181 tgattttact tttccttacc ctcaatttag tgagctaata aattattctt cttcaaaagg
      241 ttgagattta tctagtaact ctaaaacatt aatggtaggt agcaacattg cttcactgct
      301 atcaattgcc gaaactattg aaacaataga acgtaaataa tgataaagaa tagcagtacc
      361 atttacgtat agaatatcgg tgatattttc atctatattt atttcaaaat atcctattac
      421 agttacagat atttttttca tggcatcttt gtcaactaaa gaaacactaa gttttacggc
      481 tccatgacta taatcatctg tatgaccaac cttaactatg ggatataata tatcgaaggt
      541 aaatgtgaac aaactgatta ggaaatttaa accaacttct aacaatctgt tatactcaat
      601 gaaaaccaaa gagcaaacta ggaaactagc ctcaggttgc tcaaaacact gttttgaggt
      661 tgtagatgga actgacgtag tcagctcaaa acactgtttt gaggttgtag atggaactga
      721 cgtagtcagc tcaaaacact gttttgaggt tgtggataga actgacgtag tcagctcaaa
      781 acactgtttt gaggttgtgg atagaactga cgtagtcagc tcaaaacact gttttgaggt
      841 tgtggataga actgacgaag tcagctcaaa acactgtttt gaggttgtgg atagaactga
      901 cgaagtcagt aaccatacgc acggcaaggc gacgttgacg tggtttgaag agattttcga
      961 agagtattag aaagctcgat ggactattcc agattcattc cactagattt cgaaatcgag
     1021 taggggataa tctctagccc ctctcacacc accgtacgtg ccgttcggca tacggcggtt
     1081 caactaactg ttaacgcatg tcattcaagg taataatcca aacacgaaac cagtccacgt
     1141 ttttcaagga ctggttttga tatagcacgt ttaagtaccg acttctgagc tactaattga
     1201 tagtggtcgc cccagccaga taccttatcc gctatatagg ccttattatc acgttcctgt
     1261 tcgtagagcc acgatttcgc tatcccttcc tctgacgatt cttatttcca gcgtcagact
     1321 taaaacggtc tatccccaga ccgttttaat ccgctacctc acgatagtca gacttgggaa
     1381 tcgctattgg gttcaccggt agcaggtgcc caccgaggac ttacacctca aatatataat
     1441 aaaatgaaat aagaatagga cgaatcgatc aggacagtca aatcaatttc taacaatgtt
     1501 ttagaagtag atgtgtacta ttctagtttc aatctactat acaacatgcc cgtcgtacat
     1561 caaaaaaagt tgagacatag cgtcttcaac ttttttacat tactttaact actgattaaa
     1621 gtgagtttac gtcaactttg ataccaacac cttgagtagt tgtgatagtc aagtttgtta
     1681 cgtaagttcc tttagctgta gctggttttg ctttttggat tgtttcgttg aaagctttaa
     1741 agttttcaac caatttttca gcttcaaatg atactttacc gatgattgct tgaacgttac
     1801 ctgcacggtc agcacggtaa gtgattttac cacctttaga ctcttcaact gctttagcaa
     1861 catccattgt tacagtacca gttttagggt ttggcatcaa gttacgtggt ccaaggacac
     1921 gtccaagacg tccaacaaga gccatcatat caggtgtagc gataactacg tcgaagtcca
     1981 accaaccgtc gttgatttta gcaacaaggt catcttcacc aacaaagtct gcaccagcag
     2041 cttttgcttc ttcagctttt gcaccacgtg cgaaaacaag aacacgtgaa gttttaccag
     2101 taccgtttgg caataccatt gctccacgga tttgttggtc agctttttta acgtcgatgt
     2161 tcaagttgta agcaacttct acagttgcat caaattttgc aaagttagtt tcttttgcaa
     2221 gtgctacagc ttcttctaca ctgtatgctt ttgtgctgtc gattttctca agagcagcac
     2281 gaagttgttt gcttttttta gccattttct attctccttg taagtggttc aatcgatttt
     2341 catctcccac gtcacttctc gaaatgatga agtcttgcgg gttttcagtc tactattttt
     2401 ctcttcctac ggccttaagc tcccttgctg tacccaagta caagcctcag tcacttgcct
     2461 agtatgaaaa gcaactaata gactgctgtg agattttcta ctgtgttatt gattagtcaa
     2521 caacagtgaa tcccatagaa cgagcagtac cttcgatcat acgcattgca gactctacgt
     2581 ttgctgcgtt caaatctggc atcttagttt ctgcaatttc ttgtacttgt gcacgagtaa
     2641 ctgtagcaac tttagtttta ttaggtgtac ctgatccttt ttcaacacct gcagcttttt
     2701 tcaaaagaac agcagctggt ggtgttttcg taacgaaagt aaatgattta tcttcgtaaa
     2761 ctgagataac aactggaatg atcataccag cttggtcagc tgtacgagcg ttgaactctt
     2821 ttgtgaatcc catgatgttg ataccagctt gaccaagagc aggtccaacc ggtggagctg
     2881 gtgtagcttt accagcaggg atttgcaatt ttacaagttt ttcgactttt ttagccattt
     2941 ttaaatcctc ctttgtggtt ttggcggtaa ttagagattt ttacctccca caagtatgtt
     3001 tttcacatac ccatccatta tacactattt atctggaatt gcaagagaaa agtttatttt
     3061 ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggctg ctcaaaatac
     3121 agctttgagg ttgcagataa aactgacgaa gtcagctcaa aacactgttt tgaggttgtg
     3181 aatagaaccg acgcagtcag taggtaaggc gacgctgacg tggtctgaag agattttcga
     3241 agagtattaa tcgacgtagt ctccgccttc aaagccatag tattcttcca aactgagacc
     3301 gcttgcagca atttctttag cttcttttcc tacataacgc aggtgccatt cctcagccat
     3361 atagcctgtt tccttttcct tgcctttgag ataacggaca acaaagccat aatcagctgc
     3421 atggtccaag agccattggg ctgctttttc ttctgtcacc aaatcaccat cagtcccaat
     3481 cacatcaaag gccaagcctg tctggtgttc gctatagcca ggacgggcag agtaacggtc
     3541 agctgctgcc tttccatctt ggttgacata atcttgatag agcttggtct gagtttcata
     3601 acttctaaaa ccactgtaat gatcactaat agggaaacct gcctcttgca tcgctttgat
     3661 gagtttgacc aactcagcct tggctgttgg attttccccg ggattatagt ctttcgacaa
     3721 aggataatgt ttattggcta cgatgatttc gtcgtatttt ccttggatgc tgtagtaatc
     3781 acctttattg accacttctg cttttttctg ggcagcccct tgagacttac tgccgactgt
     3841 cccatcagct ttggctgtct gttctgtctt agctgtgcca tcttcatttt ttgctttttc
     3901 ttgtgaacaa gctgctagac tcaaggctag caaggctgtc acgacaaggt atcttttctt
     3961 catttctact cctttatttc taatagttta tctacttctg atgataaacg tttgactaat
     4021 cttttgatct catccggttt tgcttggcag gtttctgctg tcatttcttc aaaaggaacc
     4081 caccaaactg gaccacgtcc cttgagaccg tgaccattca tatcacctgt ccgtcgtgga
     4141 aacagatgcc aatgaagatg ggcatcgcca tttcctaaaa gttcaatatt cattttctca
     4201 gcagtaaagg ccttagcaac tgcctcttgg attagactca tttcttctag aaaacggagt
     4261 cttgtctcct ttttcaaatg gtgcaattcg gtgacatgtt ccttggctag aaagagacta
     4321 tagcctacaa aatactgatg gtctccaatc acaagatagc ctgtttccaa ctctcttaca
     4381 aagtaaggat tttctccctt cttgatgagc tcaattctct ggcaaatcaa acacatatta
     4441 gtctaccaac gcgctcttaa ggtaagcatc aaccatacgc tccgtcgcga caactgaatc
     4501 aatatgagta cgctcataag aatgactaga ctcgattccc gctccaagga gagcatgttt
     4561 gacttctgct cctgcagaca tagccgctga agcgtccgat ccataaaatg gatagatatc
     4621 cagcttaaat ggaatatctt gctctttcgc caaagctact aagtgttgac ggaagtcata
     4681 gtgataagga ccggaagcat ccttgacaca gatagatact gtgtactcat ccgtctgttg
     4741 gtcatcgccc atagctccca tatccacagc cagatattct actacctctt ctggaatatt
     4801 tgaattggca ccatgcccca cttcttcaaa cactgaaaaa gcaaagtgtg tcgtcatcgg
     4861 caagtcaatt ccttcttctt tataaactcg aaggagattg agcaaaatgg ctgcactgac
     4921 tttgtcatcc aagtggcgag acttgataaa accagtttcc gtcacaactg ttcgcggatc
     4981 aaaactaata aagtcaccaa cctcaatacc caaggcacgt gtttcttttt cattggtcac
     5041 tttttcgtct aaacgcactt ccatattgtc ctgagtgcgt tcagcagttc ctgcatcttt
     5101 gtagacatgg caagatgtct ggtggataag gatagttcca gataccgttt tacctgtact
     5161 agccacatga acggtacagt tttctccctc aatcatgttc caaggaaaac caccgatacg
     5221 gtccaatttg agacgtccgt caggtttgac agcacgtaca atggctccga gtgtatccac
     5281 atgggcggtt acatagcgat gttgttcatc attttgacct ttaatggtca cattgacacc
     5341 gcccttggct gtacgaaccg gctggtaacc aagctcttct aaagtatgga ctaggtattc
     5401 tgaaatctca cgagtaaagc ccgttggaga tgcaatagcg gttaattctt tgatatagtt
     5461 tacagtttga ttcatttctt cacctctttc gctacctatt ataacacatt tatcatcgga
     5521 taaaaaaaga aaatcactcc tgtagacttg gctacaaaag tgatttaagt gattattcca
     5581 tttcaaaaac atcgctttct tgcttgtttg gtagaaccaa tgagagcaag attccaacaa
     5641 tggctggcac caaccatggg agagatgcct tggcaaaagg aagaacgcta acaagatttg
     5701 caagaaactc aaccttaaac gagcttccta gtacgcttgc aatggcaata actgtaacca
     5761 cagcaattgt caactgcata cctggttttg aaagggcaac aaatttgttg acaatgacaa
     5821 tcataacgat agcaatcgtg attgggtaca agataaccag tactggaatt gagtacttga
     5881 taatcgcatc aagacccaaa ttggcaatag caaatccaat caaggtaaag gctgtcgcat
     5941 aaaccttgta gctgatttgt gggaagcgct cattaaagaa ctcagctgtt gacacaatca
     6001 aaccaacagt cgttgtgaag caggttacgg taaccatagc tgcaaggaag agttgagctg
     6061 ttgagccaaa gatttcttga gtggcttgtg acaagatgta aacacctggt gttccaccct
     6121 tcatcgcttc agctggtact gggaaatgat ttccaagaaa acctaaaccg atgtaaagag
     6181 cgctgaaggc aagggcaaca acgataccaa caacccaaat agttgaaatg tattctttct
     6241 tacttgaaaa tccaagttgt ttcaaggttt gaactgcgat tacgctaaag gccactgagg
     6301 caagggcgtc caaggtattg taaccttcta ggaaacctgt accaaaggca gaagcttgat
     6361 aagcagctga agcagcttga ggacttgttc caccatattt gatagctccc agaacgacca
     6421 agataacaat caaaattgca aagactggcg ttaaaatacg tccaatgcgg tctaagattt
     6481 ttgatggatt aagcgaaatc aaataggctg ccgcaaaata cagaaccgta aatacaatca
     6541 agccaagtcc tttatttgca tccgacaaaa gggggctaat tcctacttcg taagctgttg
     6601 tagcagtacg tggggtagca aagaatggac cgattgacaa gtaaagaact gagaggtaaa
     6661 gagtcgcaaa ccaaggcgct atcttcgttg aaatctcgta gatatatcct ttaggattta
     6721 gcgttccaat aataagggtc aagacggcga taccaacgcc tgaaaagaca aaacctgcga
     6781 tggcaggaag aaaatgttct ccagatagag cacctagaga aggcggaaaa atcaagttcc
     6841 ccgcaccaaa aaatattcca aacaggagca aacctgttag ggtacctttt ttagccataa
     6901 aaatctcctt catatttata aaatactgac ctagtatacc acgattagga gtctgaaaaa
     6961 agcatcacga ggcaaatatt aaatgttttc aattttctta aaaataagaa ttatctaaaa
     7021 ataaaactct cctacccagt ccacaccaag taggagaaat gcaaaatttt aaagttcttc
     7081 aaaggctaac atgccaccct ggacattgat aacattataa ccttgttcta ataggaattg
     7141 gcaagcacgc gccgatctca ttccagattt gcaaataata taatgcaagc gatctttgtc
     7201 caattaatca taactatcag ccaattgact aagcggtagg ttgtaggcac cttctaaatg
     7261 aagagctgca aactcatcca cttctctcac atccactaga gaaaactgat cgttttggta
     7321 aagctggtaa aatgcgtcaa aggctatttc tttcattctt tttcttctaa tactcttcga
     7381 aaatctcttc aaaccacgtc agcgtcgcct taccgtgcgt atgttaccga cttcgtcagt
     7441 tttatctgca acttcaaagc tgtactttga gcagcctacg actagcttcc tagtttgctc
     7501 tttgattttc attgactata aaatcgtttt aattcttttt ttcaaatctg gcactacttc
     7561 tgcctcaaac caaggatttt tggccatcca gatttgattt cgtggtgatg ggtgaactag
     7621 cggaaaatag gctggcagat agtctttata gtgtttcacc ctctccgtta ccttcccact
     7681 gattttctcc tgtaaatagt aggcttgggc atattgccca atcaagaggg ttaactgaat
     7741 atcaggcaat tcctgtaaga gctgcggatg ccatttttct gcaaaacctg tacgaggcgg
     7801 aagatcaccc gacttgccat gtcctggaaa gtagaaatcc ataggcaaaa cagcaaaata
     7861 acctgaattg taaaaggtat cttcatccac acctagccag tcccgcaagc ggtcaccact
     7921 tttatctttc cagtaaaggc ctgcttcttg agttttaagt cccggagcct gaccgatgat
     7981 attgatgcga gcagtttttg gcgctgcaaa gagaggctca atgccacgct ctgtatagct
     8041 ggcattctgt gaatccgcca tgatagcctg tttgattctt tcgatttgag acatctactt
     8101 tccctccaaa aagaagtcca agcataagat ctcagacttc tatcgtttta tttgatcaat
     8161 tcgtaaatag cttcggcata aattgctgct gctcggaaaa gatcatccaa ggcgataaat
     8221 tcattggctt ggtgcatggt atcaatcgag tctgggaaca tagcaccgta ggcaactccg
     8281 cgttctagca agcgaccaaa ggttccacca ccgatgactt gttcatgacc tttaaggcca
     8341 gtttgttttt catagatatt caacaaggtt tgcacaagtg gatcttccat tggcacatag
     8401 tgaggcgtgt gaccgtgttc agacaggcta acagaaacaa ctggcaagtt ttcaaggatt
     8461 gacttgattt gttctggact tgttcctttt ggatagcgga tgttgagggc aatggtatta
     8521 tcagcacttg tttcatcgaa gcggaagacg ccggcattca tagaaagagc acccatcttt
     8581 tcatccacat gagcaatctt aagattttca ccctcatgat cgttcaagag aattttacct
     8641 gcgatgtcaa ggtagtcttt ggctggacca gcaaagccaa actggctgag gaagagggca
     8701 aggtaagttg cgccattgac acctgaagca ggcatagcac cgtgggctga tttaccaatg
     8761 atcgtcacct tgtatttgcc agcttcttct tggagttctc ctctaagttt gtgttctgca
     8821 acaaaggcat ctagtttagc ttgcaagtca gccaagtcac ctgaaacgac tgctgttgct
     8881 gattctggta ccatattttc acgtaaacca cctgtaaagc tgtgaagacg ggcaacacct
     8941 gtattttctc ctgcaaagtg gaggtattcc gtgatatttc ctttttcacc attgatgatt
     9001 ggaaattcag catctggtga gaaaccgaaa tctggtttgg caagtcctac gtgctcaaag
     9061 tagtagtcca tgtctgccca gcctgattct tcgtctgttc caacgatgaa gcgaactttc
     9121 ttagaagttg gaagacccaa ttctttgatg attttcaaac catagtaaca agctgttgta
     9181 ggacccttat cgtccgaagc cccgcgcgca taaaggcgac catctttgat agttggtgtg
     9241 taagggtctg tgtcccaacc gctaccagca ggcaccacat ccatatgggc aaagattccg
     9301 agaacttctt ctccatcacc aaactcaaaa tgtcctgcat agttatcaac attcttagtt
     9361 gggtagccat cgcggtctgc gatttcaagg aatttctcca aggcttttac tggaccaggc
     9421 ccaaatggat gctgggcatc agccttgctg tcatcacgtt ctgaattgat ttccaaaagg
     9481 ctaaacaagt cagccaagag gtcttctttg cgtttttcta cttctgctgt aaaatcaatt
     9541 gctgtcattt tttcttcttt ctatcttttc tcgatgattt catctactgg caagcggtag
     9601 cttggttcca atttttcgtc tgtataaccc actgtgatca agagttctgg gcggaaacgg
     9661 tcttcgattt ccaaaacttc attaactttt gatttgtcaa aaccaagaat aatgttagaa
     9721 ccaattcctt ggtctgtcaa tgcaagaacc aagttcatgg caaccaaacc tgcattgaga
     9781 gctaggtagt cgctgacttg ttgctcactg taacgggcaa actcagctgg cagatttttc
     9841 ataaaatatt gaagttgctc ttcagaaaag ttattagcac caccaacacg ggcaatctta
     9901 cgagcacgtt tggctaagtc cgtatctgta aacaaggcaa tggttacagg cgctgatgat
     9961 acctgttcaa aattggaacc ataagctaac tttgccagtt cagcattttt ctcacgtacc
    10021 accacaaatt tccaaggctg gctgttgtgg gcgcttggcg ccaaggttgc aatttcgata
    10081 gccgtacgca catctttggg atcaacaggc ttatcagtaa aatgcttagt cgcatgacgt
    10141 tttttattta attcaagaaa tttcataatc gatttccttt tctaattcta ctgcttccat
    10201 tctaccataa tttgaaagag cttgcaggga tttttcatga ttaagttttt ctatcacaga
    10261 cataaaagat atatattggt ttatcaggaa agtttctgat aaactagcaa gtactttaca
    10321 tttgaatgga gacagtatga aaaaatttag cctattacta gctatcctac catttttggt
    10381 tgcctgtggg aatcaagcta cacccaaaga gactagcgct caaaagacaa tcgtccttgc
    10441 tacagctggc gacgtgccac catttgacta cgaagacaag ggcaatctga caggcttcga
    10501 tatcgaagtt ttaaaggcag tagatgaaaa actcagcgac tacgagattc aattccaaag
    10561 aaccgcctgg gagagcatct tcccaggact tgattctggt cactatcagg ctgcggccaa
    10621 taacttgagt tacacaaaag agcgtgctga aaaatacctt tactcgcttc caatttccaa
    10681 caatcccctc gtccttgtca gcaacaagaa aaatcctttg acttctcttg accagatcgc
    10741 tggtaaaaca acacaagagg ataccggaac ttctaacgct caattcatca ataactggaa
    10801 tcagaaacac actgataatc ccgctacaat taatttttct ggtgaggata ttggtaaacg
    10861 aatcctagac cttgctaacg gagagtttga tttcctagtt tttgacaagg tatccgttca
    10921 aaagattatc aaggaccgtg gtttagacct ctcagtcgtt gatttacctt ctgcagatag
    10981 ccccagcaac tatatcgttt tctcaagcga ccaaaaagag tttaaagagc aatttgataa
    11041 agcgctcaaa gaactctatc aagacggaac ccttgaaaaa ctcagcaata cctatctagg
    11101 tggttcttac ctcccagatc aatctcagtt acaataacac tcttcgaaaa tctcttcaaa
    11161 ccacgtcagc tttatctgca acctcaaagc tgtgctttga gcaacctacg gctagcttcc
    11221 tagtttgctc tttgattttc attgagtata agatatacta aaagcgattg gaccagccaa
    11281 tcgctttttt agtttgcatt ggctatttta ggaaactctt acaaaaaatc aaaaaaatcc
    11341 ttcacatcct ctacataccc atgcttttct attaagctgg ctaataattc cagattgtgc
    11401 ccctgatagt tatcttcacg acgcagttct tcatacattt cgataaaggg aagccccttg
    11461 gacttggcca attctaactc agcttcgtaa tcataagcaa ctttacgaaa ttggatattg
    11521 agtaattctc catcttcaac ttctatcacg gcatactggg cacggtgatt ttttaacgcc
    11581 tcccaattaa aatagggcat gccaatcgac cctggattga tgatttgttg cccttgactt
    11641 ccataacgaa gcaactgctt gtgaacatga ccataaactg ccacgtccgt ttccgcatct
    11701 agtagttggt caaatttctc tgtatcattc tcaactagca agtcaccacc atagtttttg
    11761 tcaggtaaat tatgagagat agaaaagcgc aatccgtcaa tttctttctt ttccagcaaa
    11821 ggcaagcttc gtagccagac aatcgttgca ggatccattc gctccatcaa aaactgggtc
    11881 atacgcaaga gctgaacttc ctgtgggtct tctaagccat attgcccatc taaagcctca
    11941 aggacacgat catcccaatt gcctcgaaca cttgctgtga taggaaggtc ctttagcagg
    12001 gcgactaagt catttgcgcc tggaccagga agaaaaatat ctcccagaag ccaatattca
    12061 ctggcccctt gatttttagc atctgcaatc actgcttcta gcgccgtcgc attgccatga
    12121 acatctgata aaattgcgat tttatggttc attgtggttt ccttccgttt ggtaatctac
    12181 tctttcttct gctacttgag gcaaggcttc tccctgcggg ttcaactttc tttgcacagc
    12241 ctctgcaacg actctaggta ccccaacttc gacaatctca tccacactgg cttccttgat
    12301 tttggtcaaa gacttgaaat gcttcataag attctgcttg cgtttaggtc ccagaccgtc
    12361 aatcccatcc aattgagatg agaaagaatt tttggagcgc agttggcggt ggaaggtaat
    12421 ggcaaagcgg tgcacctcat cttggatgcg ttggaggagg aaaaattcct gagaattgcg
    12481 agacaagtcc accacctcaa gcggatctcc aaagagcaat tcatgggttt ggtgcttatc
    12541 attcttttgc agcccagcaa ttggaatatc caagcccagt tcctcttgga taacctgctt
    12601 agcgatattg acttgacctt gccccccatc aatcacaatc aaatctggag gagtcaaagc
    12661 ctcacgctgt actcgaccat agcgtctgcg aatgacctct ctcatgctgg catagtcgtc
    12721 tggtccaaca accgttttta tcttgtactt acggtaatcc ttcttactcg gtttaccgtt
    12781 gacaaagacc accatagccg aaacagggct agttcccatg atattagagt tatcgaagga
    12841 ctcgatacgt actggggtcg ggatttggag caaacgtcct agattttcaa tagctccttg
    12901 ggtcttctcg acagatttct ctagcaggtt aaatttctgc tccagactaa cacgtgcatt
    12961 ttttatggct agattgacca gctgtttttt ctctccacgt tggggtttga gaatcttggt
    13021 atccaccaaa gccttgacag cctcttcgtc aatatcctgc ggaatcagta cctcattggg
    13081 aactaggtga gatttttctt gatagaattg tcctacatag gtcaaaaaat cctcatctgg
    13141 atcattgaag taggggaaga gattgacatc gcgctcgatg agcttaccct gacggacaaa
    13201 gaaaacctgc acacacatcc agcccttatc cacatagtag ccaaagacat cgcgattttg
    13261 gagatcctta gccatgaccc gttgcttggt tcgaagcgtt ccaatagcct gaatcaggtc
    13321 acggtattcc gccgcacgtt caaactccat agtctgggct gccgctgcca ttttgccctt
    13381 tagctcatca atgattttgt tatcctgccc tttcagaaaa tcagaaacct cctgggccat
    13441 agacttgaaa taagtctcat ccttcttaca gatggtgtgg gccatgcatt gaccgatatg
    13501 gtaataaaaa cagaccttag agggcgggtt ggtacactta cgaaaaggga atatccgatc
    13561 cagcaaccgc ttgatttcat tggctgcccc cacatcggga tagggtccaa aataaagacc
    13621 tccgtccttt ttgacctgac gagtgataat caagcgtgga tagcgctcat tggtgatttt
    13681 gatgaaagga taggacttgt catccttgag catgatattg tacttgggct tgttttcctt
    13741 gatcaggttg atttctagga gaagtgcctc aatattagac tccgtaacaa taaattcaaa
    13801 atccacaatt tcagacacca gagcctctgt cttggtatca tgacttccac gaaaatagga
    13861 ccgtactcga ttacgcagat ttttagcctt tcctacatag ataatggtgc catttttatc
    13921 cttatgaatg tagcaaccag ggctggtcgg caagagctct agttttgatt taatcaagtt
    13981 gttcatagtt ccattatagc aaaaaaagta gggaaagata gtaccctact cactagtctc
    14041 atatattttt cggaggtttg caacatcctc ttcctggata ccataaaagg aacctgctgg
    14101 ttgcatgaca gacttctcat ctgtatggtc caagccaatc gcatgaccta actcatgttc
    14161 tgccgtatgg acaaggcgtt cataggagta gccatagtat ggattggaca aataataatg
    14221 attcaaccgc accgttacgg acaagaattg ccctgttaag agattagttt gactttccgc
    14281 ctctcctgcc acaggagtgc ctccgtcgtt catctccgta gccgtaatat ccgccttact
    14341 agactcagtc acgagttcaa agttaaaagc acccgtttga ttccagttct ggattgcttc
    14401 taaataagcc tcttgaaagc gtgaatccat ctgcggatcc aggtaaatac gagcagaggc
    14461 ctgtgcccac cttccttcag aatgctggtg actatctgtc tggcttaact taggcagttg
    14521 ccctgttttc tcccattggt caatactttg ttgaccaatt tttactgacc gttctgcttg
    14581 ctttagcgct ccttgaaaat ccccgttcag ataccagaga agtccgaaag caagcacaca
    14641 taagagcaca actatccaaa ccagacgcca aaacaaacgc cacacaaaag aaaagaaagc
    14701 ccctatcaaa cgaaaaagcc agcgcatgtc tctccacctt tctagcaaat aagaattatt
    14761 ttactaaaag aagctaaaag aaatctaaat actgactttt tcatcttaac gtcctactat
    14821 ttttttgagt aactggatag ctttgtattt taaaggcgat ggatggtaac ggaaagtacc
    14881 cgctttgcgt acaatatagc cattaaaatt ctgtttaaaa cgcaaaacac catcacttcc
    14941 atcaaaaatc ccttgaatgc ctaggaagtt gtatttaggt attccacgtt ttatgctttc
    15001 caacataaca tatttttgaa gcagtgcagg ggcatagaac ttattaaact cagtgtagga
    15061 accactaaag agataagtcg tttcctgagg catataaaca aataaactac cagctaaaac
    15121 aatatcttct tctccatatt tttcaatcaa gtctcgcgct tctgcttttc gaacttcaaa
    15181 cgtttcaaat tgactagaat attctctcag ttgattttgt tttttctcag aatgaggatt
    15241 tttactcaaa tcaagtcgca acttgtccaa tttttcttct agtttacttt gttcaccttg
    15301 caatttgctc atatactccg aaaaattcaa gcttgctatg agaaactccg cttgttctcc
    15361 aaaagtatca taaaaatgct cataatattc taaactttta tcactatatt ctctacgttc
    15421 agaggtttct tttgttatat tcttaaaaat cgatagttct tcacgtttta actttttcaa
    15481 ccgaatgcca aaggtttcag cctttttcac caagggttta ccctttttgc taaaactttt
    15541 aagcaaactc ttttcagtta attcagttaa atctttatag tataaccaat ctggttctcc
    15601 acctgggtaa cctgttgtta agccatcaaa ttgataacct aaatcagtca aaccttgaat
    15661 aatacttttt ttctcagcat ctattggatt accttggcta tcaaaagttt gataagtttc
    15721 ataaggtttt acaagcaact ctaatacacc attttgcttg gcatattctt ttaactctgc
    15781 ataaaaaact ggaagagcat cttgttgggt ataaatcggc cccgaattga gttccatatg
    15841 cagaccaccc agcatgggca agctataaac cagagctgca acttgaattt ctccttcttg
    15901 tttcaaagca agataaacaa ttcgagcccc tcttttttct agcaaatccc ccatctggac
    15961 agattgcata aaggaacgag aagaaacctg atcagaataa gtctgaaact cttctttcgt
    16021 gagtgttgtt agtgccatat acttactttc tatgtttttt tcttaatgtt ttacggaaat
    16081 caagagcaag tcttaacaga ggatagagag gatgagtggg cattgtaaat tcacccaagt
    16141 attcttcaat cgttggatta aatttttcct taaaatgata aagtccacca ttgagagagt
    16201 tttcaacacc acctaaattt tgccagacca tacctcgctc aaaggcatag cgagccgttt
    16261 cataccatgt taaaattggt gcattgtaac gtttaaaatc atcatccata ccagcatata
    16321 tattgacaga ggtagtacca aattccaaac tcaaagtagc cgctaaagga actctcgctt
    16381 gacctacatc tatatattcc tgcaagaagg tcaattcctc taacaaacgt tctttttcct
    16441 tcttctgcgc ttctactttt gaagttcgag tcgactcagt aaaggtctct tccaaggctc
    16501 tatttttcgc taactgttct tctaattctt gcgaacgttt agaaacatcc aaggtggcca
    16561 aggtgatata ggccttgtcc ttaaaattat ctaacaattt tttataatag gcttcattcc
    16621 tcaaatgaat ctcttttcgc ttctcagttt ttttcatcaa ctccgaaaat gaatctaata
    16681 gttccagtcc accatattga atctcaagcc ctttgtttcg tgctgttcga atagcctgtt
    16741 ttgttgactt ggaaagttta tcttcttcaa aattttcctt gtatattttc gcctgaatac
    16801 gaggttgaat ggtgtctccc atttcctccg tttttcctga ccaccttact cccatttgtt
    16861 gcaaactatc aataatagcc agattttcag gaaattctgt cttttcctga ttgattaaac
    16921 tttgagatag gcaaatactt gggtcaaaag tcacaaaaac cgctctctta ctgcgagcat
    16981 aggacttaat agactgaatg gcaaaattca agagttcttt atccccataa tccaatatag
    17041 gtcctcttgg gatgtaaaac attttatagc ctagcggaag agttctaatc aaaatactag
    17101 ctgtcgccag taatttttct tccctgtaaa caccaaactt ctcatgttgc caattagact
    17161 taacttcctc ccaagcacta ctttgtaata cattggctaa ttcatgttct ttgacaaact
    17221 gatcatattc taatgtggga atgccaattt gataacggta catttcctac tctctttcct
    17281 ccagtatttt attactattc tactactttc gtttgaaaag tctagtgaaa acatatttta
    17341 ttttagttct actcccccta tgctgaagtt caaactaagt cagtctctct tctaatttga
    17401 aatcaattgg tagggttgtt aaaaaaactt ccaattgttt ttcccagtag taccactcgt
    17461 gagttccagc gctatggcta taggtcacat caaaacctag ttttttgaga tttttcactg
    17521 cgagattatt ggcttcgtac aagaaatcct gttcgccaca ccacgcccaa agtttggtct
    17581 ttttatccga ttttttagcc agactttcaa gagaataggg actagttgtc cagtctttaa
    17641 tctctccaaa aacacctctc cagtaggctg gacttcccag attttgactt tcaggagaaa
    17701 agttttgaaa gctgagggca cctgaaaaac tagctgcatg agaaaaacga tttgtcgtaa
    17761 gagccagttt gaagcagccg tagcctccca tagaaagacc agcgataaag gtcttttcac
    17821 gcttgctagt catattaggg aagaagcgtt tcagaacctg tggcaattcc tctgctagag
    17881 ccatgtagta gtcaaaacca tactgggtat cggtgtacca accattgctg gtattgggca
    17941 taacaacgat gagattagtt cctcgaagca agcgttctac attggtccgc ttaagccaac
    18001 tattatgatt tccagacatc ccgtgcaaaa ggtacaagac gggaatatct tcacactctg
    18061 gttcttccac tcgattggca tcagggtaga ggacattcac cccccactcc atatccaata
    18121 cttgtgagta atactcgatt ttcattactg ccatgatttt ctccttctat ttttctataa
    18181 gaaaaagccg aaactcgact ttctctctgt ttatttcaac gattattttg cttccatgac
    18241 tactggtaaa atagctggac gacgcttggt ttggtcaaag agatacttgg tcaaattatc
    18301 tcgaaccttc cctttaagat ctgcccagtc aaagtcatct ccttgaagat actcttctac
    18361 cgtttggtta atcaattctg aactttcacg gagaatatcg cgactcttct tgagataaac
    18421 aaatccgcgc gtatgaacac gagccctagc cacaattttc ttctcacgac ggttgactgt
    18481 aatagccacg atgaaaattc catcctctga caagacctta cggtcacgaa gaacaacatt
    18541 tccaacatca ccaatggcat tcccatcaat taagatatct cctgctgaaa ccgatccagc
    18601 tggaacaaag tctccattct cgtaagccat ggtcgtcccc tttttaggaa tgaagatgcg
    18661 ttctggcaac atcccaactg ccatggcagc cttagcgtga gcatccaact cacgatactc
    18721 cccttggaca gggaagaggt acttaggttg caaaagattg atcatcagct gcaaatcacg
    18781 cacatttccg tgccctgata catgtaaact ttgggtaatc aatttgacaa ccccacctgc
    18841 ctgataaatc atattttcca cacgcgcaac aaaggcttct ttagcaatag acggagccgt
    18901 agcaatatag accaggtccc catccttgat ttctacataa cgatggcgac caatcgacat
    18961 cttacgaagt ccattgatag gttcacccat acgacctgtc tcaagaataa tcaactcatg
    19021 gtcttcaaag cgagacatat ctttaggctt aatcaagaga atttcgttgg ctaaagacaa
    19081 cttcttaaga cgaatcgctg tgcggacgat attttcaata tcaaatcctg tcaagacgat
    19141 acgtcgacct gttttatccg cagcgtcaaa aatctgctga atacgagaaa gattactgga
    19201 aacagctgca acgatgatac gaccttccca gtcagcaata gtttgggtaa tttcatccct
    19261 aacttcactt tcactagcca cctgaatatt gctgtctgca ttggccgaat cactgaggag
    19321 agccaggacg ccgtcacgac caatctctgc caaacgagca aaatcagttg cataagattc
    19381 actagccgtt tggtcaaatt tgaagtcacc tgtataaacg atgcttcctt ccgatgtctt
    19441 caagacaatt cccagactct ctggaacgga gtaagtcgta gggaagaagg aaaccactgt
    19501 cccaccaaaa tcaatctccg tattctcatc aatgacatgg aaatcattaa atttcttaac
    19561 ggcatcattt cctttgacaa agagctttgc caactcaatg gtcaactcag acccaaatac
    19621 aggaacttta gcctctgcca agagataagg tagagcacca atggcatccg catgcccgtg
    19681 ggtcaagaaa accccagcaa tacggtcgct attttcaaaa aggtaatcca tgtttggaat
    19741 caccacatcg acccctaatt gttcattttc aggatatttt aaccctacat tcaaaacaaa
    19801 aatggactct ccaatttcag caatgtacat attttttcca ttctcacgca caccaccaag
    19861 tgttgttaaa ctgatattac tcatttttcc tccaaaatct tagtttatct tgattatagg
    19921 gcaactctac cctcttattc taaaagttct gatactttca gccgaatctt ttcctaccat
    19981 tataccattt ttttgatgat tttcaaaatg aaggtctgtt ttcaaaaaag agttgatttc
    20041 ccaactcttt cctaacttct actctttttc catcaaaaaa tcataaattt cttgcaccgt
    20101 acccagcgcc atcatttctt ggtctttaac ggtttgtttg agattttggt aaatttgact
    20161 ttctcctatc tcccgctttg gcgcctcttt attgactgtc atcacaccat cttttatcgt
    20221 cacaaagcct agttcttcaa atacttgaat catcttgacc agcaagattt gttgaatatt
    20281 aagatatgca gccaaatctt tcagcttgta gcgaatatca aactctggga actggtaaat
    20341 agtcttgtac aatttggcaa actgatctct agtcccataa cctgtcagat aataggcctt
    20401 gtcaatatca tttttgaaat agacagcaga gaaatgctgt tcctgaaaaa tggtcttcag
    20461 ctgagtaata tcctctggaa tgttttttac gacaatagct tcactagccg caaaatttgg
    20521 cagttctcca ggaaaatcca agactggaac accttctggc aagactgcat tttttccacg
    20581 aatgttaaaa agttgaacac cttccactcg cgcatccacc atcatcaact ggagggcagt
    20641 ttggccattc cattggttga cagacaattt aaccgctaac tctagattct tggtttgaga
    20701 aaactctgtc gcccatctgc cttgaccaaa ggctaccact tcaaaactcg cctcaccctt
    20761 ggaaattttc agctttagat gggcattacc tgcccccata gtacgagcac tttcgacctg
    20821 aaaattcttg atataaaaaa taggtttctg attatccatt ccaaaaggag ctaaacgttc
    20881 aaaacttttg accgtttcca agctaagtgc ctccaaatcc aactcttcat ctaggtttaa
    20941 cttattcttg ccaccagcat ctgcaccttt ttcacgaaca taatcttcca aaacctgaga
    21001 taaatctgag agttgctcaa cttccagcgt catacccgct gcacctgcat gacctccaaa
    21061 ggcgatgaag aggtctcgat ggggatccag agcttcaaaa atatcgaccg cttccacact
    21121 acgagcactg cccttggcac gaccgtcttc tatattaaga acaatgactg tctgtcccaa
    21181 ttcttccaat aaacgaccag ccacgattcc tagaacccca ggattccagc cttccttggc
    21241 caagacctga accttcttct caggatccac catggtcttg gcttcttcat agatagactg
    21301 aacgatttcc ttgcgctctt cgtttttctg gtgaatcata agggcaatct catgcgcttc
    21361 ctcatcatca aatccagtca acaaatcaat ggcaggattg ggatcatcca agcggcccaa
    21421 ggcattcaaa cgaggagcaa tctggaaacc aaccgtttct tctgttactt cgttagcagc
    21481 aatcccagcc atgtccagca tttcttgcag accaatgcgc tgggtatgac ccaacatttc
    21541 cagaccatat tgaactaaga tacgattttc atccgtcaga ctcaccatat ctgcaatagt
    21601 tccaatagcg accaaatcaa gcaattccac ttgcacttct tctaacaagg cacaagccaa
    21661 cttgaaagca actccacaac cagccaaata tttaaaagga taatccgcat ctggatgttc
    21721 aggatggaca atagcataag catctggcag ggtttcaggc atggaatgat ggtctgtcac
    21781 aatgacatct actcccatag actgagccaa tgcaatagcc tcatgaccag caaccccatt
    21841 gtccaccgtc acaatcaagg aaattccttc ttgctcgata aagtatttat aaacactagc
    21901 attagggcca tagccatcgg taaaacgatt tggcaggtaa actcggcact cagcaccaag
    21961 ttgttccaaa ctttccttca caatagaagc cgaagtcatg ccatccgcat catagtctcc
    22021 ataaacgaga atattttccc cttcttcaat agcctgacga atccgctcca ctgccttgtc
    22081 catatcatgg agcagataag catcatgtaa gtcctccaag gaaggttcta aaaacttctt
    22141 cagactttct tggttctgaa tccctctctc aaacaataac cgagccacct caggacccag
    22201 tccagccttc ttggctatct ttgtaaaatc cgcatcttct acctgcaggg caaactgcca
    22261 ttcataagta ggtgttatca aaaagacatc cactctttct aagaattcta ttgcttcatt
    22321 ataacatgat ttagacgttt tctctatcca gattgctttt ttataacatt ttatagtata
    22381 ttgaaactag aatagtacac ctctacttct aaaatattgt tagaaatcga tttgactgtt
    22441 ccgatcgatt tgtcctgtta ttatttcaat atagtgattt tttcagatat ggtttgataa
    22501 gaacattctt ttattgtaga atcgtgttat aaaatctaac ataaatgaga tctctcatgg
    22561 ctttagtaga atttaaaaac gtcgaaaaat attacggaga ctaccacgca ctccgcaaca
    22621 tcaatctccg ttttgaaaaa ggacaagttg ttgtcctgct tggaccttct ggctctggga
    22681 agtccactct tatccgtacg atcaatggtt tagaggctgt tgacaaagga agtctcctag
    22741 tcaatgggca ccaagttgct ggtgccagcc agaaagattt ggtacctctt cgcaaggaag
    22801 tcggcatggt ttttcaacat cttaaccttt atccacacaa aacagtgtta gaaaacgtga
    22861 cacttgcgcc cattaaagtt ctaggaattg ataaaaaaga agctgaaaaa accgcccaaa
    22921 aatatctgga atttgtaaat atgtgggaca agaaagattc ctatcccgcc atgctatctg
    22981 gtggacaaaa acagcggatc gccatcgctc gtggtcttgc tatgcatccg gaactcctcc
    23041 tctttgatga accaacatct gctcttgatc ctgagactat cggagatgtt ctagcagtta
    23101 tgcagaaact ggcgcatgat gggatgaaca tgatcatcgt tacccacgaa atgggctttg
    23161 ctcgagaggt tgcggaccgc attatcttta tggccgacgg agaagtttta gtagatacga
    23221 cagatgtcga taactttttt gacaatccaa gcaaacctcg tgcccaacaa ttcctcagca
    23281 aaattatcaa ccacgaaagt gacaaagtca aataaggagg cgcctatgaa aaaaaaattc
    23341 tttttatcag cattattgat tagccttttc ggccttgctg ctgccaaacc agtccaggct
    23401 gatactagta tcgcagacat tcaaaaaaga ggcgaactgg ttgtcggtgt caaacaagac
    23461 gttcccaatt ttggttacaa agatcccaag accggtactt attctggtat cgaaaccgac
    23521 ttggccaaga tagtagctga tgaactcaag gtcaagattc gctatgtgcc ggttacagca
    23581 caaacccgcg gcccccttct agacaatgaa caggtcgata tggatatcgc gacctttacc
    23641 atcacggacg aacgcaaaaa actctacaac tttaccagtc cctactacac agacgcttct
    23701 ggatttttgg tcaataaatc tgccaaaatc aaaaagattg aggacctaaa cggcaaaacc
    23761 atcggagtcg cccaaggctc catcacccaa cgcctgatta ctgaactggg caaaaagaaa
    23821 ggtctaacct ttaaatttgt cgaacttggt tcctacccag aattgattac ttcccttcac
    23881 gctcatcgta ttgatgcctt ttccgttgac cgctctattc tgtctggcta cactagtaaa
    23941 cgcacagaac tactagatga tagtttcaag ccatctgact acggtattgt taccaagaaa
    24001 tcaaatacag agctcaacga ctatcttgat accttggtca ctaaatggag caaggatggt
    24061 agtttgcaga aactttatga ccgttacaag ctcaaaccat ctagtcatac cgcagattaa
    24121 ggaggatacc ctatgacaga tttatcatct tggacagcct attttcagga ttttggacaa
    24181 tttttcaatg gtttcctctt tactcttgcc ctagcgattg gatcctttat cctcgccatg
    24241 gtcttaggaa tcttctttgg tgccatgtca accagtaaac gtccaatttt acgcatttta
    24301 gctcgcatct ttgttgaatt ttaccaaaat actcccctct tggtgcagtt tgttattgtt
    24361 ttttatggcc tacctcttat cagtgaccat atcatcatga ttccaattta ttggacagcc
    24421 gttctctgcg tgggactcta tcacggcgct tatatcgctg aggttattcg ttcagggatt
    24481 cagtctattc ctagtggtca gatggaggcc gccttgtcgc aaggttttac ctatatcagt
    24541 gccatgcgct tgattacctt gcctcaggcc tttcgcatca ttctccctcc attgaccaac
    24601 caaattgtta acctcatcaa gaacacctct actgtagcta tcatctctgg agtagacttg
    24661 atgtttgtga ctaagtcttg gtcggctctc aacggaaact atatcccagc ctttttaggt
    24721 gctgctcttc tctactttgc cctatgcttc cctgttgccc agtttggtcg caagatggag
    24781 caagccaaca aaaaagccta ttcactttag gaggttacta tggaatctat tttagaagtt
    24841 ttaaccccag ataacctagt ctttatcttt aaaggatttg gcttgaccct ctatatttct
    24901 ctgattgcca tcatcctctc tactatcatc ggtacggtgc tagctgtcat gagaaatggc
    24961 aaaaatccta tcttacgcat tatttccagt atttatatcg agtttgtgcg caacgttccc
    25021 aaccttctct ggatttttac tatctttttg gtgttcaaaa taaagtccac accagcaggt
    25081 attacagcct ttactctctt tacatcagca gccttggctg agattattcg aggcggtctc
    25141 aatgccgtag acaagggaca atacgaagca ggaatgtcac aaggcttcac ctcagcccaa
    25201 atcctctact acatcattct cccacaagcc atccgcaaaa tgctaccagc catcatttct
    25261 cagtttgtta ccgtgattaa ggataccagt ctcctctact ctgttatcgc cctacaagaa
    25321 ctctttggag ccagccaaat tctcatgggc cgttatttcg aaccagagca ggtcttcagt
    25381 ctttacatcc tgattgccct catctacttc agctttaacc tagcaatttc tagcctgtct
    25441 catatgctag ccaaacgttg gcaacaagct gcagaataat actcttcgaa aatctcttca
    25501 aaccacgtca gcttcacctt gccgtatata tgttactgac ttcgtcagtt ctatccacaa
    25561 cctcaaaacg gtgttttgag cagcctgcgg ctagcttcct agtttgctct ttgattttca
    25621 ttgagtataa acagccactc tccagttcaa ttggagagtt ttttgatgag agtagatatt
    25681 tatagacctc aatttgacac catacatttt ctatgataaa atgtaacaaa tttatttaca
    25741 acaaatcgaa atctaaatga aatggaattt tctatgaaat cagtcaaagg actactcttt
    25801 atcatagcta gttttatctt gactcttttg acttggatga acacttctcc ccaattcatg
    25861 attccaggac tagctttaac aagcctatct ctgactttta tcctagccac tcgtctccca
    25921 ctactagaaa gctggtttca cggtttggag aaggtctaca ccgtccacaa attcacagcc
    25981 tttctctcaa tcatcctact aatctttcat aactttagta tgggcggttt gtggggctct
    26041 cgcttagctg ctcagtttgg caatcttgcc atctatatct ttgccagcat catccttgtc
    26101 gcctatttag gcaaatacat ccaatacgaa gcttggcgat ggattcaccg cctggtttac
    26161 ctagcctata ttttaggact ctttcacatc tacatgataa tgggcaatcg tctccttaca
    26221 tttaatcttc taagttttct tgttggtagc tatgcccttt taggcttact agctggtttt
    26281 tatatcattt ttctatatca aaagatttcc ttcccctatc tagggaaaat tacccatctc
    26341 aaacgcttaa atcacgatac tagagaaatt caaatccatc ttagcagacc tttcaactat
    26401 caatcaggac aatttgcctt tctaaagatt ttccaagaag gctttgaaag tgctccgcat
    26461 cccttttcta tctcaggagg tcatggtcaa actctttact ttactgttaa aaattcaggc
    26521 gaccatacca agaatatcta tgataatctt caagccggca gcaaagtaac cctagacaga
    26581 gcttacggac acatgatcat agaagaagga cgagaaaatc aggtttggat tgctggaggt
    26641 attgggatca cccccttcat ctcttacatc cgtgaacatc ctattttaga taaacaggtt
    26701 cacttctact atagcttccg tggagatgaa aatgcagtct acctagattt actccgtaac
    26761 tatgctcaga aaaatcctaa ttttgaactc catctaatcg acagtacgaa agacggctat
    26821 cttaattttg aacaaaaaga agtgcccgaa catgcaaccg tctatatgtg tggtcctatt
    26881 tctatgatga aggcacttgc caaacagatt aagaaacaaa atccaaaaac agagcttatt
    26941 tacgaaggat tcaagttcaa ataagtaatc atactctcct gggaaatccc aggagagttt
    27001 tttatagcca aatgaaataa gacaggaacg atggaatttt ggcattcaaa tcaattgata
    27061 agaatgtttt atagtggagt gaaataggat acgaacaaat tgattaggaa aatcaaatga
    27121 atttatagaa atcttttagc agttatgttg tcctattcta gtttcaaaac gctatagaag
    27181 cagcattgtg ctagtctaga ttcagtttac tatactaaaa cgagtagctt gaaatcaaaa
    27241 aacccaccct cacaggcagg ttttatctgt attattcagc tagattatgc tttaccttct
    27301 gaaccgaata cgtcgatacg ttcttcaacc gatgcttgga tagcttttac accgtcagcc
    27361 aagaatttac gtgggtcgaa gagttttttc ttgtcgtatt ctgcttcgtt tgcttcgtag
    27421 tcacgagcaa atttacgagt tgcgttagcg aatgcgattt ggcattctgt gttaacgtta
    27481 actttggcaa caccaagttt gatagctgct tggatttgct catcaggaat acctgatcca
    27541 ccgtgcaata cgattgggaa tcctggaaga gcttctgtca atttttgcaa gtggtcaagg
    27601 tcaagacctt cccagtttac tgggtaagga ccgtggatgt taccgatacc agctgccaag
    27661 aagtcgatac cagtttcaac cattgcttta gcgtcttcga ttggagccaa ttcaccttta
    27721 ccgatgattc cgtcttcttc accaccgata gtaccaactt cagcttctac tgagatacct
    27781 ttagcgtgtg ctttttcaac aacttcttta gccaatttaa ggttttcttc aactggaagg
    27841 tgtgaaccgt caaacatgat tgaagtataa ccaacttcga tacactcaag tgcatcttcg
    27901 tagtgaccgt ggtcaaggtg gatagctact ggtacagtga tacccattga ttcaacaagg
    27961 ttagcgatca agttgcgagc aactttgtaa ccacccatgt atttagcagc acccattgaa
    28021 gtttggatca aaactggagc ttttttagct tctgctgcgc gcaagatagc ttgagtccac
    28081 tcaaggttgt ttgtgttaaa tccaccaact gcataaccgt tgtcacgggc tgcttggaca
    28141 aatttttctg ctgaaacgat tgccatttta tcaggcctcc tgtatatttt tatgggtcat
    28201 cccatttaca ttgttcattt tatcactttt tgccaaaaaa atctagtttt tcccgcagtt
    28261 tcgattgatt ttcttctaac tccatctatg taaacccttt ctctccctag tcttgggcga
    28321 cttttggaaa atctataaag aaggttaaac gattctcctc catctcgaaa cgataagcta
    28381 atttttcatg ttctaataga ctcttaacca caaagagccc cataccagac cccttgacct
    28441 tgcgactagc attgtcagaa aaagactggg ctagtttttc ttgttcctct gagctacagc
    28501 tattttcgat aaaaagttct ccttctcttt ctccaattcg aactaagcca cctggaacag
    28561 agtgcttaat ggcattgctg atgagattag aaagaatcaa cttcataact gatgggttta
    28621 gataagcctg ctgatgggtc aaactattgt ctatctggag ctctctttcc ttggctagca
    28681 aggcataatc tttgaccaga ttttgcgtca tctggaggag gtcaattgtt tccctatcat
    28741 ctcgcaattc ctgcacagaa gagagggaaa gtatctgcag aacatggtga ttgagttcat
    28801 ccacaatccc caaggcaact cccagatact ggtctctatc cttataacga ccgatattct
    28861 ctctcatatt ttcgattagg attttcaaac tagccagcgg tgttttcaat tcatgagaag
    28921 ctcctcgtag gaattcgacc ttcatcttct ccagctggag aatggcttca ttcttttcat
    28981 gcaagtccgc aataacagtc aagagatgct ggtagaggct attgatttgt tccttgagat
    29041 tacctatctc atccttagaa tccacgcgca atcgcacttg ggcatccagg tacatcatcc
    29101 gacgagtcac ccgcttgatt tccaaaatcg gtgcaacaat agtccgagcg tagatgtagg
    29161 ccaccaagag ggaaatcaga aaggaggcca gcaaggtata gggaagaaac tggagactga
    29221 tttgctccgc ttccttttgt aaatccatgg aagctagaaa ctggagaatc atagtagcac
    29281 cgtcttgcgt tttcacctcg cgctcctcaa taaagagaga ggttgtctgg cggtctgtgt
    29341 ccagaggaag actgtccttg acttctaact tgtcctcggt catctcacct ttgacggtcc
    29401 ccttgatatc actagtctgg gaatacaagt ctaacacttg ctcgatactc tgcctatctt
    29461 tcccttctag ggactgggca atggctgttg ccttttgacc aatggtttcc tgacgatgac
    29521 tcagataagt cgaaggaaaa agaaaataaa tagctaaatg aaggcagata accagaacac
    29581 taaatatcga gaaggtatag ataaatatct ttgcaaataa acctgttcgt ttcattttcg
    29641 ctccaattta taaccaacat tgcgcacagt gaggatacaa tccaagtcta gctttttccg
    29701 caattccttg atataaacat caataacacg gtcaaaggga acctcatctg tcgctttcca
    29761 gacggcatcg ataatctgag atcgagtcaa ggcccggcct tcatttttca ctagatagtc
    29821 cagaatttcc aactctttgg cattgatagg cacttcttga cctgcgaggc ttgcactgta
    29881 gctttcaaag tccaccttgg tatccttgta agaaaagatt cgtcctgtat cgtagtagcg
    29941 cttgaaaatc gcgtccaccc tcacttttaa aagggagagg gagaaaggtt tttccagata
    30001 gccatctgcc aaagaggcaa aggcactcat cttgtattcc tcatcttgaa aagctgtcaa
    30061 catcaagaca ggaacctgac tggttttacg aatctcagct aggacttcta agccgttgag
    30121 cttgggcatc tggatatcca gtaaaaccag ggccacctca tagctagaaa attgctccag
    30181 agcttcctga ccgtccgctg cctcaatagt ttcatagcca caatccgtca aataatcact
    30241 gaccccctca cggatcatct cttcatcttc tacaattaaa attttcatac tttaactgct
    30301 ctctattttt tatttttctt agaataaata cctactctat tttctattat agtctcttgc
    30361 tggccttttg tctgcaagca actgaccact agataaaacg ttgtgaaatt cctttctcat
    30421 aaattccata actttagtat attatattta agcactaaag tacaaagaaa gcaactgaaa
    30481 gcaatgattt tcatcactgc tttcggattt attttgaatt gttaaatagc cattcctatc
    30541 cactattctt gaatagaaac acaagatgca atctttattc tagactcatt ttttcaaatt
    30601 tattcaccat ccagcaagag ctcttttggt tgttttctaa ggagattgct tgaagcaagc
    30661 gccataacga gaaccactag aaccaaggca aggacaaaaa tgatgataaa gtctgatgtc
    30721 tgaatggaaa tgtctaggct cgacaaggtc ttgctaaagc catctacttc tgcaccacca
    30781 ccaaggttag aggcttgagc cgccttacta gcctgtttgg caacacctga agtcacattg
    30841 gcaaggacag tgtttccaat tgcacgggca gtgtaattag ctaggaagta agcagaaact
    30901 agagcaggga tagcaatcaa gatagattcg atgatgaatt gacccaagat acttgcctgc
    30961 ttgaggccga tagagaggag aattcccact tccttgcgac gggcgttgat ccaaaggctg
    31021 agcaagaggg caaggaggag aactgagaag ctcaagctac cccagaagag gaggttggcc
    31081 atcttgtaca taccagagat agattgctca agagctgggt agttagagga gctcttgacg
    31141 agtgtgtagc tcttccagtt gataccactg atgccattca actctttcat aacatcatcc
    31201 aagttcttgt ctgctgttac aaaaaaggtt gcgtccccat aaatggctgt gtcttctgtg
    31261 tatccataaa gttttgcagc agtgtgaatg tctgtaatag ctgtgttttc gtaaagttct
    31321 tgtgagtagg ttactgctga cttattatga ccatcaaaga gtcccttgat tgtcacttca
    31381 actgtttcct tggctccttt ttcattatct gcatcgtaga tattagagtc cagtttaacc
    31441 ttgtccccta ctttccagcc gtgtttggct gccaagtcct tgtgcaagag gattttatcc
    31501 ttgtcgtcgt tggttaagtg ctctccttcg actagtttat aagaaccaga gacaaacttg
    31561 tcttctttag aggagtcatt gacacctgta atcatcaagc tacttccaaa acgtttggca
    31621 cgatcagcag tgagattctt cttggtttct ggcgtttcaa tgaggtcata tccagtcaaa
    31681 tctccgatag cgttgatacg tttgacataa gactcgatgg ccttgttttc ggtgattttt
    31741 ttgatgtctt cacccttgat attcccagca ccacgaggcg ttccttggtt gacgcgacga
    31801 ttgatttgca tggagaagct attggtgata tttttaaagg tctcctgaga agccttggca
    31861 gtagctccct tgattgacaa gccgaccaaa ctcaagctcg ccatgaggag aataatcagg
    31921 aagatgacaa tcgatttgaa aaacttcctt gtaacatagg caaatgcgtt gtgtaacata
    31981 gattcccttt ctagattttg ttttaatcat tctatcaaaa taagctcaaa ttatttacta
    32041 gtattgcgcg tttcagtcag tttcttatcc tttaattcaa gtgtaatatc tgacgcttgt
    32101 gccacttctt tactgtgagt tacgacaatc acacatttac ctgttttctg ggcaagtgat
    32161 ttgagtagtt cgacaatatc tccagcagtt ttaggatcca gatttcctgt tggctcatca
    32221 gctagaataa ctggagcttc tgagaccaaa ctgcgagcaa tggcaacacg ttgctgttga
    32281 ccacctgata actggagaac attccgcttg atctggcttt catccaaacc aagctcaaga
    32341 agtgtatcct tgcttgcctt tttgttgacc aagcggatat tttccagcgg agaaagataa
    32401 tctatcaagt tataattttg aaagaccagg gaaatatggt gcatgcgatg gtaagaatag
    32461 cccttcttac gaatatcctc tccttgaaaa aggatagaac cttcaacagg actatctaga
    32521 ccagcaagta gggacaagag tgtggatttt cctgctcctg attccccaat aatactgtaa
    32581 aattttccgg gttcaaaatt ataatcgatc tgatatagga ctgcttcagc agtattctta
    32641 taacggtagg taacatcttg taattgtaat aaagtcatga tttctccttc ttaactaata
    32701 gatgataaaa tttctttcgg tgattttcta aataagaata ggaaacaaag ggctacagat
    32761 aagcaactaa gcagaactag aaaaacatag gattctgcaa aagataagat gctagttgat
    32821 aaactgcttg ctttggctag tgtatcttgt aagcttgcct gatctccact tgctagtaga
    32881 gtttggagta ggtaagttgt gattccattt cctgcaacaa atgctggaag caaagctcca
    32941 agagatacca aaactacctc taaacagaat tgtaggaaga tcgagctctt gccttttcca
    33001 agtgcaagta aaatccccac ttcatagacc cgttctctca accagagaga caaaaccaga
    33061 attaaggctc cagctcctgc tatcaacatc ccataaagga agatggtcag gaaggtttgg
    33121 aaagttgcaa ctgagtcttt gatttgttca aaagccttgt tttccttttc gacttggtag
    33181 ccttgatttt ccaaggccaa gttttctacc tgcttcatga gtccgtccat ttccttagga
    33241 ttttctacat agaagcgtgc tgcactgact tgagcttcac tattgcccaa aagggtttgg
    33301 ctactttcat agtctgtaaa gacttgattt tcactgaagt cagaagacaa gcctgtgaat
    33361 ttctcttgtt ttttaccaga aaagatgcca ataatctcaa actctactgt ttgtcctttt
    33421 ccagattcag actgaccagc atccaagcca atcttgtcat gaagtgaaag accgttcttc
    33481 ttagccaatt cttcgtggat aaggattttc ttggaatccc ctttttgaag gtgtcgccct
    33541 tcttttagat tgaaagccga actggtaaag gttacatcct tggatgaatc ctcaagagcc
    33601 gttaagctaa ccaagttatt gtctgcagct gataaatcat cacgctccac gctctgctcg
    33661 ccagtcactg cttccttgtc ttttagtttt gcgaccgtct caagttcagg agagacattt
    33721 tccagcccct taatcttgct tacagatgct aggtctgaca acttgaatgt ctgaccattc
    33781 tctatcttct taatagaaaa agatgtattg agtgatttat aaagattgct ttctactgtt
    33841 ttgttggact tcatcagagt caaacaggct gaaattccgg ccaataagac caataaaatc
    33901 agaaataaaa taaaacttct cagtcgcttt ctgctgacat aagcccaaga tctttggatt
    33961 ggattcattt gtcacctcca tatttgtaag actattataa aacccaaata tgaaatgttt
    34021 atgaaatacg aaaaaaaaaa a
//
LOCUS       DAVMAH010000021        33839 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVMAH010000021 DAVMAH010000000
VERSION     DAVMAH010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33839
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.021"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(16..252)
                     /locus_tag="VYO94_000927"
     CDS             complement(16..252)
                     /locus_tag="VYO94_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1759583.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(734..919)
                     /gene="briC"
                     /locus_tag="VYO94_000928"
     CDS             complement(734..919)
                     /gene="briC"
                     /locus_tag="VYO94_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV1759584.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(1077..1844)
                     /locus_tag="VYO94_000929"
     CDS             complement(1077..1844)
                     /locus_tag="VYO94_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV1759585.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(1841..2707)
                     /locus_tag="VYO94_000930"
     CDS             complement(1841..2707)
                     /locus_tag="VYO94_000930"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV1759586.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(2744..4111)
                     /gene="accC"
                     /locus_tag="VYO94_000931"
     CDS             complement(2744..4111)
                     /gene="accC"
                     /locus_tag="VYO94_000931"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV1759587.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(4123..4545)
                     /gene="fabZ"
                     /locus_tag="VYO94_000932"
     CDS             complement(4123..4545)
                     /gene="fabZ"
                     /locus_tag="VYO94_000932"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV1759588.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(4542..5027)
                     /locus_tag="VYO94_000933"
     CDS             complement(4542..5027)
                     /locus_tag="VYO94_000933"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV1759589.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(5030..6265)
                     /gene="fabF"
                     /locus_tag="VYO94_000934"
     CDS             complement(5030..6265)
                     /gene="fabF"
                     /locus_tag="VYO94_000934"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV1759590.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(6287..7018)
                     /gene="fabG"
                     /locus_tag="VYO94_000935"
     CDS             complement(6287..7018)
                     /gene="fabG"
                     /locus_tag="VYO94_000935"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV1759591.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(7052..7972)
                     /gene="fabD"
                     /locus_tag="VYO94_000936"
     CDS             complement(7052..7972)
                     /gene="fabD"
                     /locus_tag="VYO94_000936"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV1759592.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(7965..8939)
                     /gene="fabK"
                     /locus_tag="VYO94_000937"
     CDS             complement(7965..8939)
                     /gene="fabK"
                     /locus_tag="VYO94_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV1759593.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(9058..9282)
                     /locus_tag="VYO94_000938"
     CDS             complement(9058..9282)
                     /locus_tag="VYO94_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1759594.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(9342..10316)
                     /locus_tag="VYO94_000939"
     CDS             complement(9342..10316)
                     /locus_tag="VYO94_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV1759595.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(10316..10750)
                     /locus_tag="VYO94_000940"
     CDS             complement(10316..10750)
                     /locus_tag="VYO94_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1759596.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(10844..11629)
                     /locus_tag="VYO94_000941"
     CDS             complement(10844..11629)
                     /locus_tag="VYO94_000941"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV1759597.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            11954..13318
                     /locus_tag="VYO94_000942"
     CDS             11954..13318
                     /locus_tag="VYO94_000942"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV1759598.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            13321..13692
                     /locus_tag="VYO94_000943"
     CDS             13321..13692
                     /locus_tag="VYO94_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV1759599.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKVSRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            13905..15179
                     /gene="serS"
                     /locus_tag="VYO94_000944"
     CDS             13905..15179
                     /gene="serS"
                     /locus_tag="VYO94_000944"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV1759600.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(15204..16103)
                     /locus_tag="VYO94_000945"
     CDS             complement(15204..16103)
                     /locus_tag="VYO94_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV1759601.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLTE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(16213..16761)
                     /locus_tag="VYO94_000946"
     CDS             complement(16213..16761)
                     /locus_tag="VYO94_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV1759602.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(16979..18301)
                     /locus_tag="VYO94_000947"
     CDS             complement(16979..18301)
                     /locus_tag="VYO94_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV1759603.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILITGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(18392..18480)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(18644..20980)
                     /locus_tag="VYO94_000948"
     CDS             complement(18644..20980)
                     /locus_tag="VYO94_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV1759604.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(21084..21632)
                     /locus_tag="VYO94_000949"
     CDS             complement(21084..21632)
                     /locus_tag="VYO94_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV1759605.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(21629..21931)
                     /gene="zapA"
                     /locus_tag="VYO94_000950"
     CDS             complement(21629..21931)
                     /gene="zapA"
                     /locus_tag="VYO94_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV1759606.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            22018..22899
                     /locus_tag="VYO94_000951"
     CDS             22018..22899
                     /locus_tag="VYO94_000951"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV1759607.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQITPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDTFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            22903..23517
                     /gene="lepB"
                     /locus_tag="VYO94_000952"
     CDS             22903..23517
                     /gene="lepB"
                     /locus_tag="VYO94_000952"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV1759608.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            23597..23719
                     /locus_tag="VYO94_000953"
     CDS             23597..23719
                     /locus_tag="VYO94_000953"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HEV1759609.1"
                     /translation="MKIKEQTRKLAVGCLKQCFEVVDRTDEVSSKYCFEVADGS"
     gene            23796..26162
                     /locus_tag="VYO94_000954"
     CDS             23796..26162
                     /locus_tag="VYO94_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV1759610.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(26210..27493)
                     /locus_tag="VYO94_000955"
     CDS             complement(26210..27493)
                     /locus_tag="VYO94_000955"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV1759611.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEEALYQDAMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEDRIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     ATAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQSLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(28279..29415)
                     /locus_tag="VYO94_000956"
     CDS             complement(28279..29415)
                     /locus_tag="VYO94_000956"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV1759612.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVESKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(29477..29914)
                     /locus_tag="VYO94_000957"
     CDS             complement(29477..29914)
                     /locus_tag="VYO94_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1759613.1"
                     /translation="MKLEKHLIKLDKQFSNKEEAIRYCGQVLYEGGYVNENYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNESNTQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(29916..31871)
                     /locus_tag="VYO94_000958"
     CDS             complement(29916..31871)
                     /locus_tag="VYO94_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1759614.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREKEEVKRCLLMLMSKEASEEVRDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(31895..33664)
                     /locus_tag="VYO94_000959"
     CDS             complement(31895..33664)
                     /locus_tag="VYO94_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV1759615.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        10038 a         7615 c         6402 g         9784 t
ORIGIN      
        1 tttctttgcc tcccactatc taaaaaaatg ataatagata taattgtaaa caaaaatcca
       61 gataggtttt gcatgattga gaaagttaaa aaaactatgg cagagaatcg ttaatctcag
      121 attgtcggta gaacgataaa caagggcaaa aaagaaacca atcagactat aatataataa
      181 actaattgga tctctgtgag atagtatcaa atggctaatc ccaaagatga tagcagatag
      241 gataacatcc aaataatact tggactaggg aaagaaggtg ttcataaaat accctctatc
      301 aagagtctcc tcaaaaacag gaccgatgat tacaggcagg acaaaagata agatagtcga
      361 taaaaaggtt ggttgtccat ttgaaagaac cacggtaaaa tactcatcat gaatattcct
      421 atgattaatc aaatgagcat agcgtgccca aaaattaccg agaatctgat aaaccacata
      481 agttgcaaat aaggagaaga caaatgacca gtcccagctc tttttctttt ttaacctcca
      541 aattaataga aaaggaaact tcccactaat cccactgtta aaataagaga atagacatca
      601 gctcctaacc ctaaaatgat cgtcacatac aatccaattg tttgtggtaa ataggtagat
      661 agtaaaataa taagcaaaaa tattccaaat tgtcttagtt tctttgtgtt tctcatcgta
      721 cttttttgaa agattaccct gttcggaagc cgtacttcca agcatctata taagaattaa
      781 gtgccccttg cctcatatag ggagcaaatt ctctataata taaccatcta ctatatccat
      841 cttcccaaac agcaagacca cctgaagttt gctccaagtc ctcagttgaa ataactgtaa
      901 atgtttctgt acctgtcatt gcaagtacct tcttaaaata gattgttgta ggctcacatt
      961 tatagtatat ttcttttttg tctattttat agcccatctc ctcaactatc aatttttcaa
     1021 cctgaattgc atttttccat aaaaaatgag acctttctag tctcatttag tcattcttag
     1081 tattttctaa atcgttgata gcgttcttcc agcaactctt ctagcggttt ttgtgaaagt
     1141 ctagccagct ccgtttggag ttcttttttg acactcttaa tcagttcttt actagaaagt
     1201 cctacttcag aaatcacctt atccaccacg tccatttcta acagttcatg cgaagtgatt
     1261 ttcatcagtt ctgctgcttc catggcgcga gtaccgtcct tccataaaat ggaagcaaag
     1321 ccttctggac tgagaatggc atagatagaa ttttccagca tccagacacg gtccgcgaca
     1381 gctagagcca gagccccgcc tgaaccacct tcaccgataa taatggcgat aataggaact
     1441 ttcaggtcac tcatttccat gagattgcga gcgatagctt ccccttgacc acgttcttct
     1501 gctccgacac caggataagc acctgctgta ttaataaagg tcacaactgg acggccaaat
     1561 ttctcagcct gtttcatcaa ccgcagtgcc tttcggtagc cttctggatg tggttggcca
     1621 aaattccgtt tgaggttgtc ttgcaaactc ttgccttttt ggataccaac cactgttaca
     1681 gcttggtctc caagccaacc aataccacca acaactgcac catcatcacg aaaagaacgg
     1741 tcaccatgta attggataaa ttcatcaaaa atgcctgtcg caaagtccaa ggttgtcaag
     1801 cgactctgct cacgcgcttc tctgactatt tttgcaatat tcatctagga ctccctccat
     1861 gcaatctgac taggctagca atcgtatctg gtaagtctct tcttttgaca atagcatcca
     1921 caaagccatg ttctaatagg aattctgcct tttggaaatc ctcaggcaag ctttcacgaa
     1981 ccgtattttc aatcacacga cgcccagcaa aaccaaccaa gctctgtggt tcagccagaa
     2041 tgatatcgcc ttccatagcg aaagaagctg tcacaccacc agtcgttgga tctgtcaaaa
     2101 tggtcaggta aaagagacca gcatttgaat gacgtttaac cgccgcagag atcttagcca
     2161 tctgcatgag actcatgatt ccttcctgca tacgggctcc accagaggct gtgaatagga
     2221 caactggcaa tttttcgaca gtcgcatact caaacaaacg agtgattttt tcacctacaa
     2281 ccgtacccat agaagccatg ataaagttag aatccataat cccaagagcc acagtctgac
     2341 ctttaataag agcagttcct gtcacaacgg cttcatgtag acctgttttt tcacgcatag
     2401 atgccagttt cttttggtaa ccagggaaat gcaagggatc cttgctttca atccctgtaa
     2461 acaattcttt gaaggttccc atatcaatcg tcaaagccaa gcgttcttgg gcagaaatac
     2521 gaaaggtata gctacagtgc ggacagatac gttcacttcc cagatccttc tgatagatgg
     2581 tatgcttaca gcctggacac tgggaaaata attcatctgg aacctctggc ttagcttgag
     2641 gtttttccct aaccgaacga ttgggattga ttcgaatata cttatctttt ttactaaata
     2701 gagccattga ttcccctttt cggtttaaac tcttaaagtc attttattct ttttcttgat
     2761 atttaggtaa gaaggtttcc atcaagaagg aagtatcata atccccagca atgacattgc
     2821 gatctgaaat gaggtcaagc tggaaatctg cattggtctg cactccttca atctctaatt
     2881 catagagggc acgttgcatt ttcatcaagg cgtcaaaacg attttcgccg tgtactatga
     2941 ttttggcaat catactatca taataaggcg gaatggtata acctggataa actgctgaat
     3001 ccacgcgcaa gccaactcca ccacttggca gatagagatt agtaatctta cctggacttg
     3061 gagcaaagtt aaaggctggg ttttctgcat tgatacgaca ctcgatggca tgaccgcgta
     3121 ggacaatatc ttcttgctta acagacaaag gctgacctgc cgcaatgcaa atctgttcct
     3181 taacgatatc aacacctgaa acaaactctg ttactggatg ttctacctga acacgagtat
     3241 tcatctccat gaaatagaaa ttgctacttg cttcatcaag aagaaattca atggttcctg
     3301 cattctcata gccaacaaac tctgccgctc gaacagcagc agcacctatt tcatgacgca
     3361 gcgtttttcc gattgcaatc gagggacttt cttccaaaac cttttggtta ttcctttgaa
     3421 gagaacaatc ccgctcaccc aagtgaatca catgtccatg ctcatcacct aggatttgaa
     3481 cctcaatgtg ccgagctgga tagataaccc gttctatgta catggcacca ttgccataat
     3541 tggccttggc ctcactagag gcagtttcaa aggcagaaac gaggtcatct ggtttttcaa
     3601 ccttacgaat ccctttacca cctccacctg ctgaagcctt gagcataaca ggatagccaa
     3661 ttttttcagc aacaatcaaa gcttcttcag agttatgcac ttctccatct gaacctggta
     3721 taacaggcac acctgcttta atcatctgag cacgcgcatt gatcttatcc cccatcatat
     3781 ccataacatg accagatgga ccgataaact tgatacctac ttcttcacac atggtcgcaa
     3841 atttggaatt ttcactgaga aatccaaaac cagggtgaat agcttctgcc tcagtcaaga
     3901 ctgcagctga tagaactgca ttaatattga gataagactc tgttgccttg ccaggaccaa
     3961 tacaaactgc ttcatctgcc aaaagcgtat gaagagcttc cttatcagca gttgaataaa
     4021 ccgctaccgt cgcaatcccc aattcacgtg ccgcacggat aatacgaacc gcaatttcac
     4081 cacgattggc aattaaaatt tttcgaaaca tggagaacct ccttagttcc caattgcaaa
     4141 agtaaggata ccactggctg caagcttgcc atccacttca gcctttgctt caaccacagc
     4201 tatggtgcca cgacgtttta caaaagtcgc tgtcataacc aattggtcgc ctggtacaac
     4261 ttgcttcttg aacttaacct tgtccatacc agcgtaaaag accagttttc ctttattttc
     4321 aggttttgat aactccaaca caccagcagt ttgcgccaag gcttccataa tcagaacacc
     4381 tggcataact gggtattgag gaaagtggcc gttaaagaaa ggttcgttaa tggtcacatt
     4441 tttgatagca acaatggtat cctcgctcac ttccaagaca cggtccacta gaagcatagg
     4501 ataacggtgg ggaagagctt ctttgattcc ttgaatatcg atcatttgat acgtaccaat
     4561 cctttaccaa actcaaccat ttcttcgtta gagacgagaa tttccgttac cacaccatcc
     4621 ttaggagctg ggatttcatt catgactttc atggcttcga taattaccaa tgtttgacct
     4681 tttttgacac tatcaccaac tgtaacgaag gcaggtttat ctggtccagc agccaagtaa
     4741 accactccaa caagtggact ctctacaaga tttccctcag tagccacact tgcttcagct
     4801 ggagctggaa cttcttctgc tacagtctct gctggagcag atgtaggagc tactggactc
     4861 ggtgttgcta gaacgggtgc tggagcgact tgagttgcaa cttcaggcac aggtcttgct
     4921 tcattcttgc taaactgcaa ctcatccgtc ccatttttat aagaaaattc tctcaaactt
     4981 gactggtcaa attgagtcat caagtcttta atatcgttta aattcatact tatctattct
     5041 cccaacgttt gaaagcaaga actgcattgt ggcctccaaa accaaaagta tttgaaatag
     5101 cgtatggaat ttctttctcc aagccttgtc cataaacgac attagcttcg atataatctg
     5161 atacttcact tgtcccagct gtcattggta caaagttatg gcgcatagct tcgatggtga
     5221 cgatagcttc tactgcaccc gcagccccca gcaaatgtcc tgtaaaagac ttggttgatg
     5281 atacaggtac ttccttacca agaacagcta cgatagctcc actttctcct ttttcattgg
     5341 caggagttga cgttccgtga gcattgacat aggctacttg ctctggagaa atctcagctt
     5401 cttccaaggc tagtttgatg gccttgatag ctccctgacc ttctggatgt ggagaagtca
     5461 tgtggtaggc atcacaagta tttccgtaac caaccacttc agccaggata gtagctccac
     5521 gtttttcagc gtgttcaaga ctttctaaaa ccaacatccc tgaaccttca cccataacaa
     5581 acccattgcg atccttatca aatgggatcg aagcacgagt tggatcctct gtagtagaga
     5641 gagctgttaa ggcttggaaa ccagcgatgg caaaaggtgt gatagaagct tctgttcctc
     5701 ccaccaacat cacatcttgg aaaccaaact taatggaacg gaaggcatcc ccaatcgcat
     5761 catttgatga agagcaggca gtattgatag atttacaaac accgtttgca ccaaaacgca
     5821 tggctacatt cccagaagcc atatttggta aagcttttgg aagagtcatt ggtttgacac
     5881 gtttgggtcc tttttcatga aggcgaagta cctgatcttc aatttccttg attccaccaa
     5941 taccagatgc aacgataaca ccaaaacgat ccctattaag agcctctaca tcaagattgg
     6001 catgatttac agcctcttgg gctgcataca aggcatataa agaatagtta tcaaaacggt
     6061 tggtatcttt ttttacaaag tatttatcga acggaaaatc ttggatttct gccgcattat
     6121 gcacatcaaa gtcactatga tcaaattttg taatgccacc aatgccgatt ttcccagttg
     6181 ctaaactatt ccaaaattct tctggtgtat ttccgattgg agatgttact ccataacctg
     6241 ttaccactac tcgatttagt ttcattcttt tcacctctag ctttcgctac atacttaagc
     6301 caccatcaat ggcaatcact tgaccagtta gataatcttg gcctgctaaa aatactgtca
     6361 aatctgcaac ctgctctgcc tgcccaaatt ctttcatcgg aatctgagct agtgtagctt
     6421 ccttaatctt atctgataag atagcggtca tatcagactc aatcattcct ggagcaatca
     6481 cattgactcg tatattccga ctagcgacct cgcgtgccac agacttggta aagccaatca
     6541 agccagcctt agaagcagca tagttagctt gaccaatatt ccccatcaaa ccaacaacac
     6601 tagacatatt aatgatagca ccttctctgg ctttcatcat cggtttcaag actgattgtg
     6661 tcatattaaa ggcaccagtc agattgacct tgagcacttt ttcaaaatct gcttctgtca
     6721 tcttgagcat aagagtatct tgggtaatcc ctgcattgtt gaccaaaaca tctactgaac
     6781 ccagttctgc aatagcttga tcaatcatac gcttagcgtc tgcaaaatct gatacatctc
     6841 ctgaaatggg aaccaccttg ataccatagt ttgaaaactc agcgagcaat tcttctgaga
     6901 ttgccccacg actgtttaag acaatgttgg ctcctgcttg agcaaacttg tgggcgatgg
     6961 caagaccaat tccacgactc gaacctgtaa taaagatatt tttatgttct agtttcattt
     7021 ttttcctttc aaaacttcta cttattttag tctatttttc taaaagtgct actaaactcg
     7081 cttgatcttc cacatgagct aagtgagcag tttgatcaat ttttttaaca aaacctgaca
     7141 agactttccc cggtccaatc tcgataaagt tgcttatgcc tgcttcttgc atgaccccaa
     7201 tactttcata gaaacgaacg ggttccttga cctgacgcgt caagagctga gcaatgtcct
     7261 ctttttgcat cacagcagct tctgtattgc cgactagggg acaagtaaaa tctgaaaaac
     7321 ttacctgagc tagagtttca gctagtttct ggctagctgg ctcaaggaga gcggtgtgaa
     7381 agggacctga caccttaaga ggaatcaagc gtttggcacc tgcttcttgc aaaagttcaa
     7441 ccgctcgatc aactgcaacc acttctccag caatgacgat ttgtgcaggt gtgttatagt
     7501 tggctggagt aaccactcca agttcagaag ctttttgaca ggcttcttca atgacctcta
     7561 ctggcgtatt gagaactgct accatcttgc cagagtcagc aggagccgct tcttccatat
     7621 aggctccacg cttagctacc aaggcaaccg catcttcaaa atccaaggcg ccgcttgcca
     7681 ccaaggcaga gtattctcca agagacaaac cagcaaccat atcaggctga tagccctttt
     7741 cttgcaataa acggtagata gcaaccgaag tcgctagaat ggctggttgc gtatagcggg
     7801 tctgattgag tttgtcttct tccgtatcga tgagataacg caaatcataa cctagcacct
     7861 gactcgctcg atcaatcgtt tctttaacaa tcggatactg atcatagaaa tcccgtccca
     7921 tccctagata ctgggcacct tgaccagcaa ataaaaaggc tgttttagtc atttcttaca
     7981 actcctgccc agcgagaggc ttcttcttga attttcttag cggctccgta atacaaatct
     8041 tttaggattt cttcagctgt ttcttcttta gaaacaagcc ctgcgatttg acctgccata
     8101 acagagccac catccacatc accgtgaaca actgctttgg ctagagcacc tgctcccatt
     8161 tgttcaaaga tttctaaatc aggatcttcc tgcttaaagg catctttttc agccagttca
     8221 aaatctctag tcaactgatt tttaatagca cgaacagcat gaccaaagtg ctgagctgaa
     8281 atcgtagtat caatatccct tgcttttaaa attttctcct tgtagtttgg atgggcattc
     8341 gactcttttg caactacaaa ccgtgtcccc acctgtacag cctctgcacc tagcataaag
     8401 ccagccgcag caccttcacc atccgcaatt cctcctgcag caataacagg aatagatata
     8461 gctgtggcta cctgtcgcac caaggtcatg gttgttaatt taccgatatg ccccccagct
     8521 tccattcctt ctgcaataac agcgtctgca ccgatttttt ccatgcgttt agctaaagcg
     8581 acactaggaa caacaggaat aacgattatc ccagcttcat ggaaacgttc catatacttg
     8641 cttggatttc ctgctcctgt tgtgacaact ttaacacctt cttcaataac gagatccacg
     8701 atgtcttcca caaagggaga taagagcatg atgttgaccc caaagggttt atcagtcaat
     8761 gatttgattt tatcaatatt agccttgaca acttctttcg gggcatttcc cccaccgata
     8821 attcctaatc ctccagcctt ggaaacagcc cctgccaaat caccatcagc aacccaggcc
     8881 atccctcctt ggaaaatagg atagtcaatc ttcaataatt ctgtaatacg cgttttcata
     8941 gtgcctccaa ccttccttgc ttacgtaata gttcgatttc accataattt gacagtcaaa
     9001 ctattaccta aacaagaggg agtgggtttc tccctactcc ttctactaat attctgctta
     9061 ttttgcttgc tcttcaacgt aagcaaccaa gtcaccaact gttttcaagt cattttctgc
     9121 ttcgatttgg atatcaaaag catcttcgat ttctgagatt acttggaaca agtccaatga
     9181 atctgcgtcc aaatcatcaa aagttgattc aagtgttact tctgatgcgt cttttccaag
     9241 ttcttcaacg ataatttctt gtactttttc aaatactgcc atgataggac tcctttaaaa
     9301 taaatagttt ttttataaca atgtgttcac cacatgatta cctaaattgt aagaatgagc
     9361 gtgccccagg tcaagcctcc accgaagcct gatagaagaa cagtctggct accatctaaa
     9421 gggatgagac cttgttctac acactctgaa agtaaaatcg ggatactggc tgcactggta
     9481 ttgccatatt ccatcatatt ggctggaagt ttggctcggt caacaccaat ttttctagcc
     9541 atcttatcca aaatacggtc attggcttga tgaagtagca gataatccaa gtctgtcacc
     9601 tctataggag attcatcaat agtctgcttg atagacttgg ctacatctcg aatggcaaaa
     9661 tcaaagactg tgcgtccatc catcttcaaa aatgaatctg cactttcttg atctgaaaat
     9721 ggagaatgca aacctgaatg cccataagtt aaacactcgc tgcgacttcc atcgctattg
     9781 agactctcag ctaagaaatg ctcttgctcg ctagcttcta acaagacacc accagcacca
     9841 tctccaaaca acacagctgt tgatcgatcc gaccaatcga ctgccttaga gagggtttca
     9901 ctaccaatca ccaagccttt ttgaaagcga ccagaagcga taaacttttc agcagttgaa
     9961 agagcaaata caaatccact gcaagccgcg gttaagtcaa aagcaaaggc tttattagca
    10021 ccaatattag cttgaacacg agcagctgta gagggcatca tcgaatctgg agtaatggta
    10081 gctaggatga taaaatccag ttcttctcct gttattccag cttttgccat cagtttctta
    10141 gcaacctctg tagccaaatc actggtagat tctgttcttg aaatatgcct ttgtcgtatt
    10201 cccgttcgac ttgaaatcca ctcatcattg gtatccataa tctgagccaa gtcgtgattt
    10261 gtaaccactt gctctggcac ataatgagca acctgactta tttttgcaaa agccattatt
    10321 tcaaatcctc caaaaattgg taaagattag tcaagccttt acccatgaca gcaatttctt
    10381 cctcgctcat gccatcaata attttttcta ccatggcctt gtggaagcgt ttatgcagtc
    10441 tatgaatcaa gcgacccttc tttgtcaaat gcagatgcac cacacgacga tcctgttctg
    10501 accgaactcg ctcaatgtag cccttacgct ctaaattgtt caaacttgtc gtaacagttc
    10561 caagagttac catcaactct tttgacactt gacttggagt cacatctgga gccttaccga
    10621 tgacatcaat cgtatgcatt tctttgatgg agatatcctt aaaacgacta cctctcaagt
    10681 tcacttcctc aattacaagg acattgttaa atatagatgt taaatattca ttgattcgtt
    10741 ggtagtccat ttttcatatc cctccttctt caaaaaactt ttacaatcaa aacatttgac
    10801 agaaagaatt atatcaaaat tcaaagaatg atgcaaggat tttttatttt cctgtaaatt
    10861 taggtcttct tctctccgaa tgagctcgca ctccttcttt gaaatcctct gtttgagcta
    10921 aggatttctg taggttcagt tctaaagtag cgtaaccctg ccagtcttta aattggctct
    10981 cccaaaccaa cttcttaatg gcagcatagg aattacttga agcacgtctt aattttttaa
    11041 gaagctgttc tctcgtcttt tcaagttttt cagcttcaga aacgcggtaa accaaccccc
    11101 attctagggc tttttctgcc gttaaagcct ctcctgtcat agctaattga gcagcacgcg
    11161 tcacaccgat actgcggctc aagagatgaa ttccccctgc atctggagcc aaaccaacac
    11221 caacaaaggc ttggataaac ttagccttat ccgtcgccaa acagaaatct gccgcaacag
    11281 ccatattcgc tgcggcacct gcaacagcac cgtcaacttc cattaaaaca ggtttggcta
    11341 tttgcttgat tttataagaa atcgtattga ccaactctgc gatttttgtc aatgatggaa
    11401 tatcatcctc atccactgcc cgcttcatct ctaccaaatc tcccccaact gagaagacct
    11461 ttccattggc attgattaag ataaaatgca cagctggatt ttcttctgcc aaagtcagag
    11521 cttctaaaat ctcctcacac atgggaatat gaaaaccatt tgcgacctca ggacggttca
    11581 aggtaaggat tgccaagtcc tcttcaagct gataaataat gtgttccatc agggctcctt
    11641 tttattttat aagcagttta tactcttcga aaatctcttc aaaccgcgtc agcttccatc
    11701 tgcaacctca aaacagtatt ttgagctgac ttcgtctagc ttcttagttt gctctttgat
    11761 ttttattgag tgttaaatta tttcactgtc aaagtatatc ttttttagga tcagaaagca
    11821 agaaaaaatc gactgaaagt gtctcagccg ataagaaagg ctcgctttag gctagaaagc
    11881 atcttatttt cttcattgaa aaaagccttt ctttctgcta taatcgtata aaatacttac
    11941 tttaggagtt cttatgaaag ttgttaaatt tggaggtagt tctcttgcct ctgctagtca
    12001 attagaaaaa gttttaaaca tcgtcaaaag cgattcagag cgtcgttttg tagtcgtttc
    12061 tgcgcctggt aaacgcaatg ctgaagatac taaggttacg gatgccctga ttaaatacta
    12121 ccgcgactat gttgcgggta acgatattag caagagccaa agctggatta tcgaccgcta
    12181 tgctgctatg gttagtgaat tgggactaaa accagctgtg ctagaaaaaa tttctaaaag
    12241 cattcacgcc ttggccactc ttcctattga agaaaatgaa tttctctacg atactttcct
    12301 agcagccggt gaaaataaca atgccaaatt gattgctgcc tactttaacc aaaatggtat
    12361 cgatgcacgc tatatgcacc ctagagaagc tgggattgtg gtcacaagtg aacctggtca
    12421 cgctcgcatc attccatcaa gttatgacaa gattgaagaa ttgacaaaca ccaatgaagt
    12481 ccttgtcatt cctggtttct ttggtgtcac taaggaaaat caaatctgta ctttctcacg
    12541 tggaggatct gatattacag gttctatcat tgctgctggt gtcaaagccg acctctatga
    12601 aaactttacg gacgttgatg gtatctttgc agcccaccct ggtattatcc accaaccaca
    12661 ctcgattcct gagttgacct accgtgaaat gcgcgagttg gcctatgcag gcttctcagt
    12721 ccttcatgac gaggctcttc ttcctgccta ccgtggaaaa attcctctgg ttatcaagaa
    12781 taccaacaac cctgaccatc caggtactcg tatcgttcta aaacacagta atgatgaatt
    12841 tccagttgtg ggaattgctg gtgactcagg ctttgtcagc attaacatgt cgaaatacct
    12901 catgaaccgt gaggttggat ttggccgcaa ggttctgcaa atcctggaag aacttaacat
    12961 cggttgggaa catatgccaa caggtatcga cgatctttct atcattctcc gttctcgcca
    13021 actaactccc atcaaggaag aagaaatcct gcgtcagttg gttcaaaagg ctaaagtaga
    13081 tcatgcagaa atcgaacacg acctttctat cattatgatt gttggtgaaa aaatgaagag
    13141 ccatatcgga gtgactgcta ctgcgacacg cgctctatct gaaaacaaaa tcaacatcca
    13201 gatgatgtct caaggttcta gtgaagtttc tattatgttt gttgtcaata aagaccaaga
    13261 gaaagcagca attaaagccc tctacaatgc cttttttgga gaaagtaagg aagactaagc
    13321 atggctcaat cacttaacaa aacagtactc ctcagtacga caggcacttc ctacctctct
    13381 atcgctggga aagttgggaa attccttgtc ggagatcagg ctttggaatt ttacccagat
    13441 gtcaatgtcg aacaatttat ccagattcct tggagccata tcaatcagat tggagccaat
    13501 gtcactggac gcaaagtcag ccgccacttc gaagtcttta cagacaaagg aaaattcctc
    13561 tttgcttcaa aagactcagg tgccattctc aaaattgcac gcgaaaaact aggcaatgac
    13621 aaggtcgtca aacttccgac cctgattcag acaattagcc aaaaatttaa aaatctattt
    13681 gcaaaaaagt agaaacttta gtataatcat agcaacggat aagtaggtta tcttcttctt
    13741 tcagaaagtc tgcgggtgct gcgagcagat aggagggata ggtgaaattc taccgttagt
    13801 gacaattaca tacacaatca agtgcacacc tgtgaagttg gatggaaccg tggccctgcc
    13861 actccaacgt tttgtcaggg tgcttttttc ataaaggagt tcttatgtta gatatcaaac
    13921 gtattcgtac agattttgaa gctgtcgcag aaaaattagc tacacgtggt gtagatgctg
    13981 ctgtcttgaa tgaaatgaaa gaaatcgatg ctaaacgtcg taacatcttg gtcaaggttg
    14041 aaactctcaa agcagaacgt aacacagttt ctgctgagat tgcccaagct aagcgcaaca
    14101 aggaaaatac agatgacaag attgctgcca tgcaaaatct atctgctgag gttaaagcct
    14161 tggatgctga attggcagaa atcgatgcta aattgacaga atttacaacg actcttccaa
    14221 atatcccagc tgacagcgtt cctgttgggg ctgacgaaga cgacaatgtg gaagttcgcc
    14281 gttggggtac tccacgcgag tttgacttcg aacctaaagc tcactgggat ctcggtgaag
    14341 accttggtat ccttgactgg gaacgcggtg gtaaggtaac aggcgctcgc ttcctcttct
    14401 ataaaggcct cggtgctcgt ttggaacgtg ctatctacaa ctttatgttg gatgaacatg
    14461 gaaaagaagg ctatactgaa gtcatcacac cttacatagt caaccatgat tctatgtttg
    14521 gtactggtca gtatccaaaa tttaaggaag atacttttga actcagcgat accaactttg
    14581 tcttgattcc aactgctgaa gttcctctga caaactacta ccgtgatgaa atcttagacg
    14641 gcaaagatct tccaatctac ttcactgcta tgagtccgtc attccgttct gaggctggtt
    14701 ctgccggtcg tgatacgcgt ggcttgatcc gtttgcacca attccacaag gttgaaatgg
    14761 tcaaatttgc caaaccagaa gaatcttacg aagaattgga aaaaatgaca gccaacgctg
    14821 aaaacattct tcaaaaactc aaccttccat accgtgtcgt tgctctctct actggagata
    14881 tgggcttctc agctacgaag acttacgact tggaagtgtg gattccagca caaaacaatt
    14941 accgtgaaat ctcaagctgt tcaaacacag aagatttcca agcccgtcgt gcccaaatcc
    15001 gttaccgtga tgaagcagat ggcaaggtga aactccttca taccttgaac ggttctggac
    15061 ttgcagttgg acgtacagtg gctgcaattc ttgaaaatta ccaaaatgaa gatggttctg
    15121 tgaccatccc agaagcactt cgtccataca tgggtggagc tgaagtcatc aaaccataaa
    15181 aaataaggtt tagctatttc tagctagacc ttttttcgta accaaatcag ataagcacct
    15241 agtacaaaga ataaaatagt taggcatata atggtttcag tcaataccag gtaatccaga
    15301 aatggaagtt tcaaaattcc ctgagccatc ttgagcgagg tcgctgtgat aatggttggg
    15361 aaggtgaggg ctgagaaggc tggttgaaaa ccttgtttta aaatgttggg cagacgagtt
    15421 aaaacaaaga aaaagaagga ttgagaagcc aaaatcatga caatcaagac ccaagtcggc
    15481 aggctggttc ctcctactcg aactagagaa gccaagagta gagagaaagg agcacagtag
    15541 attccttctt gtccaagcaa ggctagtggg agtggatgtt tctttaaatc gctataaata
    15601 aggggataga gatagaaggt caagagaaaa ccaaaactca aggtcgcata ggcaatttcg
    15661 ataataccta ccagaggata ggtcaaggca gccactgcta tccccacata gagaaccgtc
    15721 caacttggag tggcatgaac cctccgccct ggacaagcaa acttgatggt aaaaccagca
    15781 atcaaggtca aatccaagag aaatgaaaac caccaaatcc cttgtgctac caaaggaaga
    15841 taagagaata cgcgaaagac ataggtcgat aaaatcatcc cagccatagg aaaggttgcc
    15901 attcctgaca aaagaggggg cttggtcaat tcttgcttgg tttctttcca attaaagaga
    15961 tgcagaatta gaaagtaaat ccataaaacc aaaccagtca gactaaaaag atgggataga
    16021 accggcaacg tatctaaaat aagatttcca gctcctgcca aacctagcaa acaacctgaa
    16081 aatactaagg ggagtttttt catcctaacc tccaataatc atgttagttt cagtataaca
    16141 taaaagcgct taaatgagga tttaaaaaaa cgaagtccgc ttatttcaga cttcatttta
    16201 ctcagatatg aattaggcat aaggttgcaa ttctggatta attggtgtat tagctaagtt
    16261 gttggcatag ttacagagga ttgctaggct gacaccaaaa accacatcca aggcattttg
    16321 ttgagtgtag ccagcttcta aaaactcaga caaggcttca tctcctacac gacccttggt
    16381 attgataact gccaaggtaa acttagctag ggtatccaat ttaggatctg tttcaattgg
    16441 agtacgattg cgaagagctt gaatcaagtc atcattcatc tggatttgtt tgatggaaaa
    16501 ggctgtgtga cctgcgacac agaaggcaca accattggtc acggctgccg tgatttgcac
    16561 cacttcacgc tcaacgggtg tcaggctgtt gcgacggtgg atagatgaga caatttggta
    16621 ggcttctaaa acagtcgggg cattggccaa gagaccgatt aggttgggaa tatagccatt
    16681 gttgtctttt tctactgttt caagaatttc tttcacttct gctggtgctg actctactgt
    16741 atggatagta aatgttgtca taagatacct cttttcttat tattgacact aatattattg
    16801 gaaaatctta taaaatcctg attcctaagt ttatctaaga taaagcttta ttctctcata
    16861 agattttcgt tgttatatta gtttatcaca cttccaatca cttgcataat atatattata
    16921 tatcaggctg ataaaaatta tttataggca aaaaaatcac acgagctgtg tgattccatt
    16981 atttgtcaaa atacttttta gtttcagcaa taacgactgg cgacaagacc aagagggcaa
    17041 tcaagtttgg cagagccatc aaggcgttaa cgatatctgc gataatccag accatatcca
    17101 actcgataaa tcctcctaac aagaccatga gcacaaaaac cacacggtag agccagataa
    17161 agcgagcccc aaagaggaac tcaaaacagc gttctccgta atagttccaa cctagaatcg
    17221 ttgtaaaggc aaaaagtaca aggaagatgg tcaagagggc aggcccaaag tgtgaaaaga
    17281 ctgttgagaa agctgactga gtcaaggcaa ccccattcaa gtcaccactc caaactccag
    17341 ttatcaagat ggtcaaacca gttagagtac aaatgatgag ggtatcaata aaggttcctg
    17401 tcatggaaat caaaccttgc tctactggtt catttgtctt ggcagctgca gctgcaatag
    17461 gagcagaacc cagaccagat tcgtttgaga acacaccacg cgccacacca ttttgaatag
    17521 ccatccgaac gctagcacca gcaaatccac ctaccgcagc aaggggacta aaagctgagg
    17581 taaagactaa agcgattgtg ccagggattt ttccgatatt aaagaaaata actgtaagag
    17641 ttcctaagat ataaatgagg gccataaaag gaacaacagt agttgaaacc ttagaaatag
    17701 acttgagtcc accaaagact gcaatcgcta caaagacaga caagacgaga gctgtgatgg
    17761 ctggcgaaat cgtcgttgta ttttggatag attctgtaat cgagttgact tgggtgaagg
    17821 ttccgattcc caagagagca accaatactc ctgctactgc aaacaaaaca gcaagtggtc
    17881 gccacttttc tcccatccct agaaggatat agtgcatggg acctcccgct actgcaccat
    17941 ggtcgtcctt ggtgcggtat ttgatggcca agagtccttc cgcatacttg gtagccattc
    18001 caaagaaagc cgccatccac atccaaaata gagctcctgg tccaccaacc ttgatagccg
    18061 tcgcaactcc tatgatattt cctgttccaa cagttgatgc caaggctgta cacagagctg
    18121 caaaactgga tacatcacca tgtcccttat cctggataaa aataagctga aaggccttgg
    18181 gcagacgcaa aacctgcaag agtcctagcc gcatggttag gtaaatccct gttccgacca
    18241 ataaaatcaa gaggggcggt ccccaagcaa aagcatcgat tgatttaagc aattctaaca
    18301 tttccttctc ctatcgtttc aaccccaaaa gaaagagcac atgcaagata catgtactct
    18361 ggaatgctta gataaatgct aaaaagcggt ctatcctagc tctgtccttt tacctgagag
    18421 tttgagcagt tgcctgcctt gccccttcgg tgcctttacg gtctctccag agttccgtcc
    18481 atttacagtc atggaaaatc aaacgattcc ccacttctat taaacttcat tcggtgttgg
    18541 tatttaattg attctaattt tacaaaaaat gttggctttt gtcaatgtgt ttattagtaa
    18601 aaattagttc aacagttttt actttataaa gtccagaata ctgctatcct ttaaaagtga
    18661 caatagtcgc accactgcct ccagcatttt gtggggcata gccgaaactc ttgacatgtt
    18721 tgtttctttg caagtatttg gtaactcctt cacggatgac tcctgttccg ataccatgga
    18781 tgatatcaac ttgagccata ttgttaagca aggcttggtc gatgaaggta tctagctcat
    18841 tcatggcttc ttcatagcgc ttgcctcgaa gatccagtct agcttgaggt cctcgcccag
    18901 aagttcgttt cacaacattg acctgtttct tcttgactgg tttttcttgc tgggcttgaa
    18961 caagatcaaa ctctttctct tccaaggtca tcttaatcaa gccaacttgg gcttcccagc
    19021 gaccgtcctt gagttgactg gtcaaggtac cacgctgacc ataactgaga accacgatat
    19081 catctcccac ctttggagct cgttttttct tggccttttg aaggacctta tttttagaca
    19141 agtccacttt ttcaggagcc aattttttca acttggcctt ggcttcaatg atttcgtggg
    19201 gcttgagttg ggatttactg tggagatttt tgagaatctg gtcactttca cttagggcca
    19261 tatccacaat ctcagcagcc tgttcacgcg ccttgttaag ctcggtttcc ttttcacgat
    19321 taagctcgtt gtagagtttt tttagcgcac ggttcatctt gagattttct tgctccacct
    19381 cacggatatt gtccaaacgt ttgcggcttt ccagcgtctg ctcttctaat tgctcaatga
    19441 tacgattgac gtcattgtcc tgatcgatct gctgactggc atctcctacg ataacttcag
    19501 ataggcctag acgtttggca atttcaaagg cattacttcg gccaggaaca ccctgcataa
    19561 agcgataggt cgggcgaaga gttgcagtat caaactccat actggcattt tgcacaaagg
    19621 ctgtctcaat accgtaggcc ttgagttctg gatagtgggt cgtcgccatg gtcttgattt
    19681 gacgcaggcg aaggtcctcc agaatagcca tggcaagggc tgctccctct tggggatcag
    19741 taccagcccc caactcatcc aaaagtaaga gtgaatgttg gttgaccttg ccaagaatat
    19801 ccacgatatt ggtcatatgg ctagagaagg tagacaagct ctgctcaata gactgctcat
    19861 ctccaatatc agcaaagatt tcttcaaaaa taccaacacg acttcccttg tctgctaaaa
    19921 tcggcaatcc tgactgggcc atgacctgtg tcaagcccag agttttgagc atgatggtct
    19981 tcccacctgt attgggacct gtaatgacaa tagctgttaa atcttgacca aaatagacat
    20041 catttgcgac ggcatttttg accaaaggat ggcagacatg gagcagttga atctcttgat
    20101 tttctgacag ctgaggcacg actgcttgtc tttcttggat aaatcgaacc ttggcacgaa
    20161 tcaagtccag atgaccgata atccaagcgt cattagcaat ctcagccgca tgagggcgga
    20221 cacgctcaga aatttcttgg agaatgcgaa gcatttcata gcgctcatct gctcgcagac
    20281 tagcaatttc ttcgctcagt ttgactacct cacgtggttc gatatagacg gtgtttccac
    20341 tagcagaaat atcatgaacg acacctgcaa tcttattgcg gtaggtgttt ttgactggta
    20401 aaacctgacg gccatttctg ctagcaacaa ttccttctgt caacatctgc gctttttgct
    20461 tgagcaagtc ttgtaaaaca tcgcgtacct gactctcgct atcatgtatt tttcgacgga
    20521 ttcgcgccaa ttcttcactg gcaaaatttt caatgaaacc cgcatcatta aaggcctgaa
    20581 gatttccttg taattgcgga aaatcatgta atttctcaaa ccaaagggct aattcttcca
    20641 agctgacatt ttccagattg gcgtaaaaac tttgaagttc tcggctggca agaagcacgc
    20701 gtttcaagag taggaactcc tcgatattga gatccgctcc catctccaac ctcttgcaga
    20761 ctcctgcaat ttccttagtt gagagaatag taaaatgcgg ttgctcgacg aaaagagcct
    20821 gcatttcctt catctcagca aaagcctgtt tgattttatc tgctttggca gtcggagcca
    20881 gttgtctcaa ttgctccaag ccctgctcgg tcaacaaatg aggctcaaac aaggccttga
    20941 ccttatcgaa ctctaatgtt tctaatattt tcttattcat ctttatttcc ttgtctttga
    21001 atgtctaggt gtggtagctt tttacattct gatagattcg agtcaaatct gtaaacaaag
    21061 ggctaggaaa actcctgccc tttttatccg attaaatttg tcacccagat ttgtttgagc
    21121 caactggttg ttatcggtat gctctggatg atgtgttttg cgacgatact cttttcaaga
    21181 ggattttgta taactgccat ggggatggtc gccaagattg tcaaggccat ttgcaagaca
    21241 aataaggtca ccaacatgga caagatacct gctgaaactt ggaacaactt accacccagt
    21301 tttttgctag gaatcaagtg taagagaaga ccaagcaaac gaccaatgct atagacaatc
    21361 ccaaatacaa gcaagtagcc gatgcctgca taaaagacct tatccagctg aaagagttga
    21421 tccgatggga aaaagaaagt cccctgacct tcctgcgaat ttgcataagg gagcaataaa
    21481 tggaattgct ctccaagccc cttataaaac tggccagcca taaaagccga tgccatggct
    21541 gaaatcaggt aataaacctg taagagcagg cctctccgat agccgatata aaatccccaa
    21601 accaagacca atagaagaag gaatgaaatc ataaggaatc ctcaatcttg ctctgttctt
    21661 gcttacaagt cacaagcttg tgacggagtt cttctagctc ttgctcctta tcgtcaaatt
    21721 caatctcacg gctgagctga gttgataaac agttgactgc caacaaaaga gcgattgttt
    21781 catcatctgc gctaggcatt tgttctttaa ttgcttggta tttttctgtc gcaaccttag
    21841 cgatttcctc cataaaaagg ttgtcatgtt cgcttgtcaa ggttaacgat tttttcccga
    21901 atgtaaattt gaatcgattt agatttgcca taaaattcac ctcacgatat tataccaaaa
    21961 ttcgctaatt ttgtcagttt ttacaaattt tactgctttt gtggtacaat agaaactatg
    22021 gcaagtatca cactcacacc aagcgaaaag gatattcagg cttttcttga acactatcaa
    22081 accagtctgg ctcctagcaa gaatccctat atccgctact ttttgaaact acctcaagca
    22141 acggtttcta tctatacttc tggaaaaatc ttgcttcagg gtgaaggggc tgaaaaatac
    22201 gccagtttct ttggctatca agctgtagag caaaccagcg gacaaaatct tcctttaatt
    22261 gggacagatg aggtgggaaa tggttcctac tttggtgggc ttgcagttgt ggctgccttt
    22321 gtcacacctg accagcacga ctttttacga aaactcggtg tgggggattc taagactctg
    22381 accgaccaaa agatccgtca gattactcct attctcaagg aaaaaatcca gcaccaggca
    22441 ctccttctct cacccagcaa gtacaacgag gtcatcggag accgctacaa tgctgtttcg
    22501 gttaaggttg ccctccataa tcaggctatc tatctcctcc ttcaaaaagg tgttcagcct
    22561 gagaaaattg tgattgatac ctttaccagt gctaaaaatt atgacaagta cttggcacaa
    22621 gaagccaatc gtttcagcaa tcctatcagc ttagaagaaa aggctgaggg caaatacttg
    22681 gctgtcgcag tttcttctgt cattgcgcgt gatctctttc tggaaaatct tgaaaatttg
    22741 ggacgagaac tgggttatca gctcccaagt ggagctggaa cggcttctga caaggtggct
    22801 agccagattt tgcaagccta tggtatgcag ggactcagct tctgcgccaa attgcacttt
    22861 aaaaacactg aaaaagcgaa aaaacgctta gaaaggtaag ttatgaattc atttaaaaat
    22921 ttcttaaaag agtggggatt gttcctccta attctgtcat tactagcttt aagtcgtatc
    22981 tttttttgga gcaatgttcg cgtagaagga cattccatgg atccgaccct agcggatggc
    23041 gaaattctct tcgttgtaaa acaccttcct attgaccgtt ttgatatcgt ggttgcccat
    23101 gaggaagatg gcaataagga catcgtcaag cgcgtgattg gaatgcctgg cgacaccatt
    23161 cgttacgaaa atgataaact ttacatcaat gacaaagaaa cggacgagcc ttatctagca
    23221 gactatatca aacgcttcaa ggatgacaaa ctccaaagca cttactcagg caagggcttt
    23281 gaaggaaata aaggaacttt ctttagaagt atcgctcaaa aagcccaagc cttcacagtt
    23341 gatgtcaact acaacaccaa ctttagcttt actgttccag aaggagaata ccttctcctc
    23401 ggagatgacc gcttggtttc gagcgacagc cgccacgtag gtaccttcaa agcaaaagat
    23461 atcacagggg aagctaaatt ccgcttctgg ccaatcaccc gtatcggaac attttaagag
    23521 acctaagagg ccgagaatca ccaatctcag cctcttcttc tatcgtgaga agtgattgtt
    23581 tattgacaaa tactcaatga aaatcaaaga acaaactagg aagctagccg taggctgctt
    23641 aaaacagtgt tttgaggttg tggatagaac tgacgaagtc agctcaaaat actgttttga
    23701 ggttgcagat ggaagctgac gtggtttgaa gatattttcg aagagtataa aataaaaaca
    23761 atcccaactc tcacctattc atgcaaagga attttatgga agtttatttt tcaggaacca
    23821 ttgaacggat tatttttgaa aatcccagca atttttatcg catcctcctc ctagaaatcg
    23881 acgatacgga cgcagaggat tttgatgact ttgaaatcat tgtcacagga accatggctg
    23941 atgtaattga gggcgaagac tatacttttt gggggcaaat tgtccagcac tccaagtatg
    24001 gagaacaact gcaaatcagt cgttatgatc gcgcaaaacc aactagtaag ggcttggtca
    24061 agtacttttc aagtagccat ttcaagggga ttggtctcaa gacagctcag aaaatcgtgg
    24121 atacctatgg cgaaaatacc attgacgaaa ttttgcaaca cccagaaaag ttagaaggca
    24181 tcgcaggact ctctgccaaa aatcgcgagg ctttcgtctc cactctccgt ctcaactacg
    24241 gaacggagat ggttttggcc aaactagcca actacggcat tcccaacaaa ctagcctttc
    24301 agattcaaga cttttacaag gaagaaaccc ttgatgtggt tgaaaattat ccctaccagc
    24361 tggttgagga tatcaagggt ttgggcttta ccattgctga ccaactagct gaggaactag
    24421 gcatcgaaag tcaggctcct gaacgcttcc gcgccggtct agttcacagt ctttttcagg
    24481 cctgtatgga aacaggggac acctatgttg aagcacggga tttgctggaa caaaccctta
    24541 ctctccttga gtcttcccgt cccgtagaac tagaccccag ccaagttgcc caagagctct
    24601 cctacctgat cgaagaagac aaggttcagc agattgatac caagatcttt gacaacagcc
    24661 tctttttcgc tgaggaaggc atccgcagtc acttggttcg tatccttgaa aaaggaaaac
    24721 agaagagtca tgatttagaa accattcaaa aacatatcac tactatcgag gaagagctgg
    24781 gaattgagta tgataacatt caaaaacagg ctatctgtga tgctatccag aataaggtct
    24841 ttatcctgac aggtggacct ggtactggta agacaactgt tatcaatggg atcatcgctg
    24901 tttacgccct gttagaggga cttgacctca ggaagaaaag caatctgccc attcttcttg
    24961 ctgctccaac tggacgagcc gctcgccgca tgaatgaatt gacaggtttg cctagcgcga
    25021 ccatacaccg ccacttggga atgacaggtg acgatgatac cagtcatctg gaagattacc
    25081 tagatgctga ctttatcatc gtggatgaat tctctatggt agatacttgg ctggccaatc
    25141 aactcttctc caatatctct tctaacagta agatcctcat cgtaggtgac agtgatcagc
    25201 taccttctgt cagtcctgga caggttctag cggatctgct tcatattcct ttgattcctc
    25261 agactcgctt ggaaaaaatt tatcgacaaa gcaaagaatc aaccatcgtc accctagcta
    25321 gtcagattcg acagggcatc ttgccagctg atttcaccca aaaaaaagct gaccgttcct
    25381 actttgaaat tgctagtggc catattcctg ccaccattga aaaaatctta ggtgtcgccc
    25441 tcagaaatgg tattcctgcc cgtgatatcc aagttctggc tcctatgtac cgagggacgg
    25501 cagggattga tgctatcaat cagctcatgc aagacctgct caatccccca caaaaagatc
    25561 aactcagttt tgaagctcct cagtgccact atcgtaagag agacaaggtc attcatttgg
    25621 ttaacgatgc tgaaatcaat gtctttaatg gggatttagg agctatcaca gacctgattc
    25681 ctggtaaata caccgaatcg aaacaagacg agattgtcat tgattttgat ggtaatgaag
    25741 tctcttaccc ccgtaacgaa tggtacaaga ttcgcttggc ctatgccatg agtattcata
    25801 agtctcaggg aagtgagttc ccagttgtca tcctaccgat tactagtgct agccgacgta
    25861 tgctggagcg aaatctcatc tacacagcca ttacacgtgc caaaagcaaa ctcatcttac
    25921 taggcgaatt acaagccttc gactatgcta cccaacacat cggaactgcc cgaaaaacct
    25981 atctgattga acgcttcagt gatctactgg agaatgttga agaaaagcaa caagctgtct
    26041 ctgaaacagt cacatcaagt gcctctgaac aatcctacat cctaaccgaa gaaaactggg
    26101 acagcattcc agccatgatt gggattacag acacagacct caaagagatt tttggaaaat
    26161 agtacatcag aaaacccacc aattcaggtg ggttttctgt ttattaagat tattttactg
    26221 ttgctgtgct tgtaatcaat tcaacagctt ttttgattgt gatatcatgt ttcaacatgt
    26281 cagctgaaag caagctttgt acttgagcaa cttccatgtt gtagtctgct gccaattgct
    26341 caacttcttt ttggatttct tcttctgaag catcaaatcc ttcagctttg gcaactgctt
    26401 cgataacaag gttagtctta gtacgtgact cagcttctgc ttggtattgg ttgtgaaggt
    26461 cttcttgagt agttccagtg atttggaagt acatgtcagg gttgatccct tgacgttgca
    26521 agttcccaag gaattcattt actgaacggt gaacttcttc atggatcatt tcttctggaa
    26581 gttctacgat ttcagcgttt tctacagctg tatcaattgc tgcaccttca actgcatctt
    26641 tgtaagcttc ttctttagca gtagccaatt ctttgcggta tttttctttc aagtcagcaa
    26701 gtgtttcaac ttcttcatca atgtcttttg caagttcatc gtcaagagcc ggaacttctt
    26761 tagcttttac ttcgtggata gttgtcacga atttagcttc tttacctgca aggtcttctg
    26821 cttggtagtc ttctgggaat gttacgataa catcaacggt ttcgccagct gagtgaccta
    26881 ccaattggtc ttcgaaacca gggatgaatt gacctgaacc aagtccaagt gagaagtttt
    26941 caccttttcc accgtcaaat tcaacaccgt cgatagaacc aacgaagtcg atcacaacag
    27001 tgtcgccgtt ttcagcagca gcttccttga taaccaattc agccaggttg ttgcgttcgc
    27061 gttcgatacg atcttcgaca tcagcgtcag ttacttcttt ttctacatca actgatactt
    27121 caaggttttt gtagtcaccc aattttactt caggttttgt aacgacttca gcagtgataa
    27181 cccagtcttg acctttttcc attgaagtta cgtcaatttt tggttgggca accacttcaa
    27241 gaccagcttc ttttacagct gcttcataag cgtttggcaa aagtgcgttc attgcatctt
    27301 gataaagagc ttcttcacca aatttttggt cgaagatagg gcgtggaagg tgacctttac
    27361 ggaaacctgg aacattaaga gatttcttca ctgacttgaa gacacggtcc aattctggtt
    27421 tgatttggtc ttgagagata gtgaaagtca agacaccacg gtttgtttct ttgttttcaa
    27481 atgatacaga cattctgtca tttctcctta aaatttttta aatacagtct attataacat
    27541 tttctataaa taaaatctag actaatgcag acaattatag acaacaagcc tttttcctaa
    27601 ctaaaacact cataaagtat agacaatttt agactacttt ggatatcttt tggttagtca
    27661 ttttccaaaa ctaatttatc taatttttca gttatatagt agattgaaac tagaatagta
    27721 cactgctact tctaaaacat ttttagaaat cgatttgact gtcctgatcg atttgtcctg
    27781 tttttgtttc attttactat atagatcgca ttcgaaagaa ttcgttccaa aattgcttgg
    27841 ttcgttcttc tcttggacga ctaaagaatt gatgggcatt atttttttca acaattttcc
    27901 caccgtccat aaaaataaca tgatgggcta catctctagc aaaacctatc tcataaagct
    27961 gatcaaaaac tcaatctgag gagaaaatcc aataaggctt tccataataa aggacatcct
    28021 atcaagattt ttgaacaccc gataggctgc ctttttccga ttttgaagac tttttgtcca
    28081 gcttctttta ccttataaat aacaacaaaa atcaaagaca agctagaaag attaccgcag
    28141 ataactcaaa cagtgttttg aggttgcaga caagactgac ggagtcagct caaagcactg
    28201 ctttgaggtt gtagatagaa caacatatgc ctaagacaaa gcgatgctaa cctgatttga
    28261 agagattttc gaaaaagatt aaatatactc tacaatttgc tcaatcaatt cttggtcgtc
    28321 taaacctgta acttgtataa caacatcttt gactgattgt ttagccaaca attcacctaa
    28381 tcgaatactt tcttcatcat ttacatcgcg atagtcaaag gcatagccaa ctgttttaag
    28441 taggttttta tatgacaaac tgagttcttt caattcacgt atcggccgga tgaatcgttc
    28501 attatagcct aattttcgga ttggagtacg agctacgcga ctaacctcgt ccactatgaa
    28561 agggttttca aaccgttcta taatgacttt gtgataattc tccaattctt ttttatcaaa
    28621 gttccatttg gcaatcaaga gactccgaat ttcagctaat acagattcaa tccgagattt
    28681 aatattagga ttttgaagag cttccaaaat tgtcttggca ccataatgcg caccaatgta
    28741 agctgaagtt gcatgtccag aattgactga aaaaagtttt cgctcaataa agggttctaa
    28801 atcttcttca taatgcacat cttttagacg taaatctgga tttttaagac gcttgctttc
    28861 cacgacccat tcattaaagg gctcgaccac aacaaaaagg gaatcttcgt gactttgtgc
    28921 tggaacaatc ctgtctactg cagcatttgg aaaacctatg tagttatcag caaatgtcaa
    28981 accttccgga cttaaatatt tcttgacttc ttgataaaga aattgagacc cgccaatcat
    29041 attttcacag gccataacat ccaatacctg tgtattccct gcaactcggc gagcttcgat
    29101 tcctttggct agaagttcag cgataaaagg gagtatatta ggtccgattg cagtagtaat
    29161 aatatccgtc ttttgaatcg cttcaatgac ttgctcagga tgttctttgc tattaatgcc
    29221 agccacatta gttacttcta tacgagactg tcctttctgt gcaatttcaa tttcatactt
    29281 gcccttttca tttagagcat gaattatctg attattgaca tccacaaaat caatatggaa
    29341 accattttta aatagaattt cacctataaa accacgaccg atattaccgg caccaaaatg
    29401 aacagaatgt ttcattcaat ttctcctttt cctatttgag ggacatatat actagatgac
    29461 aaatgacgaa attcaattat tcaacagcat caaataagcg caatacttcc tcttttgact
    29521 gagcatctgc tagtttaaga acattatcca catctgcaca gaagatagaa attttctgaa
    29581 taatttctaa gtgttcatta ccaataccag caataccaaa aagaaccgtt gccacttgag
    29641 tgttagattc attcccaaaa tcaacccctc ttgggacttg aacgactgta ataccagact
    29701 tgaggacatc ctttttcgct gcatctgttc catgcggtat ggcgataaag ttacccatgt
    29761 aaacagatag ctctttatca cgctcaatca tggcttcaat atagttttca ttaacatatc
    29821 caccctcata aagaacttgc ccacaataac ggatagcttc ctccttgtta gaaaattgtt
    29881 tatcaagctt aatcaaatgt ttttcaagtt tcatattagt tctccaattt cttaattttt
    29941 tcgttaaaaa tagtatttag catctgataa ataatggatt gatttcccgt cttgtaaatc
    30001 tctgtataaa gatgattttc aataatcgac tgactgatag ctgtcattaa atctctcact
    30061 tcctcgctag cctccttaga cattagcatt aacagacacc ttttgacctc ttctttctct
    30121 cgtttcattg acaatgcgga gataggtagt ttgagttcaa acatagtaaa actatttgtt
    30181 gttactttgc tagactgact atgtaaaagc accagaccag tattaggaat agccatagga
    30241 ctattctgga agtgagataa caattttctt gttaggtaat ctctgtcact cacattcttc
    30301 tgatattgga tgatttgttc taccgtgtgc tcaaatgatt gattattctc caattgaacc
    30361 aactcaaatt gactcaaaag ctgactacta gatattaaat aatcttgcaa gtcataactt
    30421 ttctctggag cgatagcatc acgcgcgaca attgtacgat gtgcctgtac atactgaagt
    30481 cgttcctgta attcaagcaa ttctttgacg gttggaaaac tagaaattac atcgatttcc
    30541 tgattagtca gcggcttggt agataaaata taatcatact gactgagatc aatactgtgg
    30601 taatctacta gagactgaat atctatcaac tctacaaaag gagcaacact cttaatttta
    30661 ctgactaata aatctctagt gacccgacgt tcatccgtta aaagcaaaac acggactgga
    30721 taaatctctg gactacggcc taagctagag ataaaatgta gggcaatcat gccatactca
    30781 tactctgtat gaagatattt cggaaaaata tcattcacta aaagactgat gactgtataa
    30841 agaaatttat tcctttcaac taaaatctgg acagattctg gcaaattttc accctgaaaa
    30901 aggataggga cgcctaaact gagccgaata tgatggaaaa gaaaattgaa taaaaccttg
    30961 tccttaaaaa agtcaatctt ggtatacatg gaaaccgtat caatcagatt tgaaatattg
    31021 tagaaaaatt caccatcaaa tttctccgta aagagcggat tgtcctgacg tttaatgatt
    31081 aattcatcca agatgctcgc aaaatagata atttcctgaa tactataaaa ttgtgcagtc
    31141 tgcttagagt aagcttgaaa aattttttga gaaatttcca aagcctgctt actagtatta
    31201 ggtgaatttt caatgttttg ctcctgacct ataagagata acaagatcgc aaaaaacatc
    31261 ttcatcctag catccatatc cggaaaacct gacagttgct tattaacaat ctgactggcc
    31321 agcctagttc tatctgcttc taaaatatca aagctcccaa aattaccggt tgaaaaatct
    31381 gctactgaga tacagtttgt cagtaaaata gccaaaaatc ttctcttacc aactgaatca
    31441 ccagaaatcc gataaccttt ttgtcgttca attttcagat caaagtctaa aagacgctta
    31501 tcaatatctg aaatatcctg aataatagtt acattactga ctttcgtgca ctcttgcaat
    31561 gcttcattgg tgacaaaacc gctctcagtc agaaggcgat aggtaatcaa ctcttgtctt
    31621 tcttggggac tatactcaac taacacttca agttctgtcg gcaaatcatc caactctcca
    31681 gtcaaaatat agtatttccc atgcttcgtt atttcgattc catattgctc catgctatct
    31741 gtcaaatctg ataaagttcg ataaattgtt ctagatgaaa cctgtaagat ttcagtcata
    31801 tcttgcattg aaagcttccc tacatgtagg aaagccttca ataattgttc ttctcgtttg
    31861 gttaatagca ttcgtaattt agaaacctct agttctattt gtacattcta gcagccattt
    31921 tgtcatattc tggtgttgtt actaaactat ccacaataag aaattgagaa ttcggtgctg
    31981 cttgctgcac ttctgcctgt aaagaaatag ttgttacaat cattatgttt ttagaattaa
    32041 attcacctaa ttctgaaatt ttggcagtag aaactggaat acgaatattc ttgtttctaa
    32101 agatagcccg aatcgtttca cagcccatag ttgcagttcc ctgtgcttta ccataagcaa
    32161 ctactacagc atcaatatgg ttaaggtcaa tttcctgact atctactggt gctgaagttg
    32221 gtatatctcc ttcaatttct gctattggag aagctcctgt taatgaagct acaatttcat
    32281 cataacgagg ggacgctaag aaattatcaa cagaaacatg aatagcactt ggactcttgt
    32341 ctttagctct tggtgtcagt tcttcctgag taacaattaa tgtttttggt gtatcaagca
    32401 aatttgagat tgcctgatta gatactggaa tctctagacc tgctttttta accttatctc
    32461 gaagaatact agctcccata gcagagcttc ccataccagc atcgcaggcg aaaatgattt
    32521 tttccactga gtctgtcgaa acaactgcat caacagaagt tgatactaac tgacctttag
    32581 actgagcctt agctgcttgg gtagccgcct gagcagcttc gagcgaatcc tcagttgact
    32641 tgtctgcatg aagaataagg gctgctacaa ggaaagaaac aactgctgct actaaaacac
    32701 ctagaagaac atttagatgg ggccaaacac cttttggcgc cgtagccata atcgcaataa
    32761 tagaacctgg tgaagctgga gatttaagac cagcgtctaa gagttgaaaa gtaaaagttc
    32821 cagagatacc tcctgccata gcagctaaaa atagagtagg cttcatcata acataaggaa
    32881 agtaaatttc atgaatccct ccgaagaaat gaataaccat tgccccccaa gaagaagatt
    32941 tagcagaacc tttaccgaat acagcataag ctaatagaat tcccaggcct ggtccaggat
    33001 tagcttccaa taggaagaga attgacttac cagcttgagc tacctgttct actcccagag
    33061 gagtaaaaat gccatgattg agggcattat tgaggaaaag gactttagcc ggttcgatga
    33121 taatattagc cataggaagg aggcgagcat tgacaatagc ctcaacacca ttcccaacag
    33181 ctccagtaag agtcgatacg actggaccga ttgcgtagaa agccaaaagc aataatgcaa
    33241 aaccaacgag accagctgag aagttattaa ctaacatttc aaatccggga cgaatttttt
    33301 cttggaactt ctcatcaaat ttcttgatag tccatcctcc cagtgggccc attaccatag
    33361 ctccgataaa cataggaaca ctagaacctg tgattgcacc aacagtagca atagctccta
    33421 caacggcacc acgttggcca tggatcatat atccacctgt gtaaccaatc aggattggca
    33481 ataaatacgt taacatagga ccaacaacag tagctaactg ttcatttggc agatagccat
    33541 cagcgataaa gagggcagtc aatactcccc aagcaataaa tgctccaata ttgggcataa
    33601 ccatatttga aagcgatgtc cctagttttt gaaccctgac tttcaatgat actttttctt
    33661 ccattagatc atcctccttt tcttaaaact agtatataca aagttaaaaa cctttaaaac
    33721 taaagttttg tcacagattt tgtgtcaaaa cattactttt gacgaggctg ggcaaaaagg
    33781 cttaaaaatt ataaaacgca tcatatcagg tgtacatgaa ctgcccccca aaagttaga
//
LOCUS       DAVMAH010000022        33295 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVMAH010000022 DAVMAH010000000
VERSION     DAVMAH010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33295
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.022"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            169..666
                     /locus_tag="VYO94_000960"
     CDS             169..666
                     /locus_tag="VYO94_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV1759616.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            666..2321
                     /gene="dnaX"
                     /locus_tag="VYO94_000961"
     CDS             666..2321
                     /gene="dnaX"
                     /locus_tag="VYO94_000961"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV1759617.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2349..2543
                     /locus_tag="VYO94_000962"
     CDS             2349..2543
                     /locus_tag="VYO94_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV1759618.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2693..3463
                     /gene="sufC"
                     /locus_tag="VYO94_000963"
     CDS             2693..3463
                     /gene="sufC"
                     /locus_tag="VYO94_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV1759619.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPEMAARLEREGYAKLAEELGYDYKEEL"
     gene            3491..4753
                     /gene="sufD"
                     /locus_tag="VYO94_000964"
     CDS             3491..4753
                     /gene="sufD"
                     /locus_tag="VYO94_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV1759620.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4764..5990
                     /locus_tag="VYO94_000965"
     CDS             4764..5990
                     /locus_tag="VYO94_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1759621.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVINPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5977..6417
                     /locus_tag="VYO94_000966"
     CDS             5977..6417
                     /locus_tag="VYO94_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV1759622.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6471..7883
                     /gene="sufB"
                     /locus_tag="VYO94_000967"
     CDS             6471..7883
                     /gene="sufB"
                     /locus_tag="VYO94_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV1759623.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8082..9323)
                     /locus_tag="VYO94_000968"
     CDS             complement(8082..9323)
                     /locus_tag="VYO94_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV1759624.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9426..10535
                     /locus_tag="VYO94_000969"
     CDS             9426..10535
                     /locus_tag="VYO94_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1759625.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAH
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11181..11528
                     /gene="ssrA"
                     /locus_tag="VYO94_000970"
     tmRNA           11181..11528
                     /gene="ssrA"
                     /locus_tag="VYO94_000970"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11711..11798)
                     /locus_tag="VYO94_000971"
     tRNA            complement(11711..11798)
                     /locus_tag="VYO94_000971"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11762..11764),aa:Ser,seq:gga)
     gene            11961..12701
                     /locus_tag="VYO94_000972"
     CDS             11961..12701
                     /locus_tag="VYO94_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1759626.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12698..13609
                     /gene="pfkB"
                     /locus_tag="VYO94_000973"
     CDS             12698..13609
                     /gene="pfkB"
                     /locus_tag="VYO94_000973"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV1759627.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13606..15558
                     /locus_tag="VYO94_000974"
     CDS             13606..15558
                     /locus_tag="VYO94_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1759628.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHSYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQVP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15722..17947
                     /locus_tag="VYO94_000975"
     CDS             15722..17947
                     /locus_tag="VYO94_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1759629.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(18098..18529)
                     /locus_tag="VYO94_000976"
     CDS             complement(18098..18529)
                     /locus_tag="VYO94_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759630.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSV
                     KEEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            18667..19809
                     /locus_tag="VYO94_000977"
     CDS             18667..19809
                     /locus_tag="VYO94_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1759631.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19818..21032
                     /gene="thiI"
                     /locus_tag="VYO94_000978"
     CDS             19818..21032
                     /gene="thiI"
                     /locus_tag="VYO94_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV1759632.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            21167..21991
                     /locus_tag="VYO94_000979"
     CDS             21167..21991
                     /locus_tag="VYO94_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1759633.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            22004..23170
                     /locus_tag="VYO94_000980"
     CDS             22004..23170
                     /locus_tag="VYO94_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1759634.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(23661..25331)
                     /locus_tag="VYO94_000981"
     CDS             complement(23661..25331)
                     /locus_tag="VYO94_000981"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV1759635.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            25561..26250
                     /gene="coaB"
                     /locus_tag="VYO94_000982"
     CDS             25561..26250
                     /gene="coaB"
                     /locus_tag="VYO94_000982"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV1759636.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLLEMQERVQYYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLEEFLSRQNHQAKISSTDEIQVLFLKKTPKIISLVKEWNPAIHLIGFKLL
                     VDVNEDYLVDIAKKSLIKNQADLIIANDLTQISANQHRAIFVEKDQLQTVQTKEEIAE
                     LLLEKIQTYHS"
     gene            26262..26813
                     /gene="coaC"
                     /locus_tag="VYO94_000983"
     CDS             26262..26813
                     /gene="coaC"
                     /locus_tag="VYO94_000983"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV1759637.1"
                     /translation="MAHILLAVTGSIASYKSADLVSSLKKQGHHVTVLMTQAATEFIQ
                     PLTLQVLSQNSVHLDVMKEPYPDQVNHIELGKKADLFIVAPATANTIAKLAHGFADNM
                     VTCTALALPSHIPKLIAPAMNTKMYDHPATQANLKTLETYGYQLIAPKESLLACGDHG
                     RGALTDLTIILERIKETLDEKTL"
     gene            26797..27360
                     /locus_tag="VYO94_000984"
     CDS             26797..27360
                     /locus_tag="VYO94_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1759638.1"
                     /translation="MKKHSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            27642..28169
                     /locus_tag="VYO94_000985"
     CDS             27642..28169
                     /locus_tag="VYO94_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1759639.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            28181..28696
                     /locus_tag="VYO94_000986"
     CDS             28181..28696
                     /locus_tag="VYO94_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV1759640.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(28693..29160)
                     /locus_tag="VYO94_000987"
     CDS             complement(28693..29160)
                     /locus_tag="VYO94_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1759641.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(29233..29721)
                     /locus_tag="VYO94_000988"
     CDS             complement(29233..29721)
                     /locus_tag="VYO94_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1759642.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKTALTALNRFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFN
                     SK"
     gene            complement(29687..30250)
                     /locus_tag="VYO94_000989"
     CDS             complement(29687..30250)
                     /locus_tag="VYO94_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1759643.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKLESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            complement(30260..32248)
                     /gene="uvrB"
                     /locus_tag="VYO94_000990"
     CDS             complement(30260..32248)
                     /gene="uvrB"
                     /locus_tag="VYO94_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV1759644.1"
                     /translation="MINRITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AIFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINNLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(32325..33278)
                     /locus_tag="VYO94_000991"
     CDS             complement(32325..33278)
                     /locus_tag="VYO94_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1759645.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMASLVLLLLIVYLANKLKKENERM"
BASE COUNT         9805 a         6596 c         6937 g         9957 t
ORIGIN      
        1 gtcgcttttc attatagatc ttatgggact ttttttctac aataaaatag gctccataat
       61 atctataggg gggttaccca ctacaaatat tatagagccc aaaatccttt gtttactaaa
      121 caagggattt ttcttttgtc tctgctcctt ttttgatata atagttctat gttaaaatca
      181 gaaaaacaat cacgttatca aatgttaaat gaagaattgt ccttcctatt ggaaggcgaa
      241 accaatgttt tggctaatct ttccaacgcc agtgctctca taaaatcacg ttttcctaat
      301 accgtatttg caggctttta tttgttcgat ggaaaggaat tggttttagg ccccttccaa
      361 ggaggtgttt cctgcatccg tattgcacta ggcaagggtg tttgtggtga ggcagctcac
      421 tttcaggaaa ctgttattgt tggagatgtg acgacctatc tcaactatat ttcttgtgat
      481 agtctagcta aaagtgaaat tgtggtgccg atgatgaaga atggtcagtt acttggagtt
      541 ctggatctgg attcttcaga gattgaggat tacgatgcta tggatcgaga ttatttggaa
      601 caatttgtcg ctattttgct tgaaaagaca acatgggact ttacgatgtt tgaggaaaaa
      661 tcttaatgta tcaagcactt tatcgaaaat atagaagtca aaacttctcc cagttagttg
      721 gtcaagaagt tgtggctaag actcttaaac aagcggtgga gcaagagaaa ataagtcacg
      781 cttatctttt ttctggtcct cgtggaacgg gaaaaaccag tgttgctaaa atctttgcca
      841 aggctatgaa ctgtcccaat caagtgggtg gcgaaccttg caataactgc tatatttgtc
      901 aagcagtgac ggacggtagt ttagaagatg tcattgaaat ggatgcagct tctaataatg
      961 gggtagatga aattcgcgaa attcgtgata aatctaccta tgcgcctagc cttgctcgtt
     1021 ataaggttta tatcatagat gaggttcaca tgctgtctac aggggctttt aatgccctcc
     1081 taaagacgct ggaagaacca acacagaatg tagtctttat tttggccact actgaattgc
     1141 acaagattcc tgctactatt ctatcccgtg tgcaacgttt tgagtttaaa tcaattaaga
     1201 cacaggatat taaggaacat attcactata tcttagaaaa agaaaatatc agttctgaac
     1261 cagaggctgt ggaaatcatt gccagacggg cggaaggtgg aatgcgggac gccttgtcta
     1321 ttttggatca agccctgagt ttgacacagg gaaatgagct gacgactgct atctctgaag
     1381 aaattactgg caccattagc ctatcagcct tggatgatta tgtggcggcc ttgtctcaac
     1441 aggatgttcc caaagctttg tcttgcttga atcttctttt tgacaatggt aagagcatga
     1501 ctcgttttgt gaccgatctt ttgcactatt taagagactt gttaattgtt caaacagggg
     1561 gagaaaatac tcatcatagt tcagtctttg tagaaaattt ggcacttcct caaaaaaatc
     1621 tgtttgaaat gattcgctta gcaacagtga gtttagcaga tattaagtct agtttgcagc
     1681 ccaagattta tgctgaaatg atgaccgtcc gtttggcgga aatcaagccc gaaccagctc
     1741 tatcaggagc ggttgaaaat gaaattgcta cgctgagaca ggaagttgcc cgtctcaaac
     1801 aagagctttc taatgtaggt gcggttccta aacaagttgc accagctcct agtcgaccag
     1861 ctacgggcaa aacagtctat cgtgtcgatc gcaataaagt gcaatctatc ttacaagagg
     1921 ccgtcgaaaa tcctgattta gcacgtcaaa atctaattcg tttgcagaat gcctggggag
     1981 aggtaattga aagtctaggt gggccggaca aggctctgct agttggttct caaccggttg
     2041 ctgccaatga acaccatgct attcttgctt ttgagtctaa cttcaatgct ggtcaaacta
     2101 tgaaacgaga caatctcaat accatgtttg gtaatatcct cagtcaggcg gcaggttttt
     2161 cacctgagat tttagctatt tccatggagg aatggaaaga agttcgcgca gccttttcag
     2221 ccaaagccaa atcttctcaa actgaaaaag aagtagaaga aagcctgatt ccagaaggat
     2281 ttgaattttt ggctgataaa gtgaaggtag aggaagacta aagaaagatt tcatgataca
     2341 ataagtttat gaataaacaa caatttatta ttatggcgct gtttacagct gctgagacct
     2401 attttttcaa tgaagcctgg atgactggcc gctatattat ggcagccttt tgggcaattt
     2461 tactctttag aaatttccga gtcagttatg tgatgggcaa aatcgttgat gtcatcgatc
     2521 agcattttaa taggaaagac tagccctcag cttccagaca aaatcaaagc cttttaggct
     2581 tttttttgtt atactagaaa agtatattta tagaattttt gctctatttc tggggaaatc
     2641 agacgttttt ctagtaagta ctgtaaaagt tttgaaaaag aaaggaacta tcatgtcagt
     2701 attagagatt aaagatcttc acgttgagat tgaaggaaaa gaaattttaa aaggggttaa
     2761 cctgaccctg aaaacaggag aaattgccgc tatcatggga ccaaatggta caggtaaatc
     2821 gactctttct gccgctatca tgggaaatcc aaactatgaa gtaactaaag gtgaagtttt
     2881 gtttgatggc gtaaacatcc ttgagttgga agtggatgag cgtgcgcgta tgggactttt
     2941 ccttgctatg caatacccat cagaaatccc tggaattacc aatgctgagt ttcttcgtgc
     3001 cgctatgaat gcgggtaaag aagatgatga gaagatttca gttcgtgagt ttattactaa
     3061 gctagatgaa aaaatggaat tgctcaacat gaaagaagaa atggcagagc gttacctcaa
     3121 cgaaggcttc tctggtggtg agaaaaaacg caatgaaatt cttcaacttt tgatgttgga
     3181 gccaacattt gctcttttgg acgagattga ctcaggtctt gatattgacg ctcttaaagt
     3241 tgtgtctaaa ggtgtcaatg ccatgcgtgg tgaaggtttt ggtgctatga tcatcactca
     3301 ctaccaacgt cttttgaact atatcacacc tgatgtggta cacgtgatga tggaaggtcg
     3361 tgttgtcctt tctggtggtc cagaaatggc tgcgcgtttg gaacgtgaag gatacgcaaa
     3421 attagctgaa gaacttggct acgactacaa ggaagaattg taatttcctc gtatctttta
     3481 ggagaagtaa atgactagag aaaatattaa acttttttca gaaatgcacg ctgaaccaag
     3541 ctggttggct gatctccgtc aaaaagcttt tgacaagatt gagactttgg aattaccagt
     3601 tattgagcgt gtcaaattcc accgttggaa tctgggtgat ggaacgatta cagaaaatga
     3661 gccatcagca aatgttccag atttcacagc tttagatcat cacttgaagt tggtgcaagt
     3721 aggaactcaa actgttttcg aacaaactcc agttgagtta gctgaacagg gtgttgtctt
     3781 cacagacttt cactcagctt tagaagaaat tccagagctg atcgaagaat tcttcatgtc
     3841 atctgttaag tatgatgatg acaagttggc ggcttaccac acagcttact ttaacagtgg
     3901 tgctgtactc tatattccag ataacgtaga aatcacagag ccaattgaag gaattttcta
     3961 ccaagatagc gatagcaatg tgccgtttaa caagcatatt atgattatcg ctggtaaaaa
     4021 ttctaagatt agttatctgg agcgtttaga gtcacgcggt gaaggaagtg acaaagtaac
     4081 tgccaatatc acagtggaag tgattgcacg ttctggtgcg caagtcaagt ttgctgctat
     4141 cgaccgtcta ggtgaaaacg tcactgccta cattagccgt cgtggtaaat taggcaacga
     4201 tgcaagtatt gactgggcta tcggtgtcat gaacgaagga aatgtcgttg ctgattttga
     4261 tagtgacttg attggtaatg gtagccatgc tgacctcaag gttgtagctc tttcaagtgg
     4321 tcgtcaggta caagggattg atactcgtgt aactaactat ggctgcaact ctatcggaaa
     4381 tatcctacaa catggggtta tccttgaaaa agcaactttg actttcaatg gtatcggcca
     4441 catcatcaag ggtgctaagg gagcagatgc gcaacaagag agccgtgttc tcatgctttc
     4501 agaccaagcg cgttcagatg ctaacccaat tcttttgatt gatgaaaatg atgtcactgc
     4561 aggacacgca gcgtctatcg gacaagttga tccagaagac atgtattacc tcatgagtcg
     4621 tggattggat aaggcaactg cagagcgttt ggttgttcgt ggtttccttg gatctgttat
     4681 cgtggagatt ccagtcaagg aagttcgtga tgaaatgatt gcaactatcg aagagaaatt
     4741 gtcaaaacgc taaggggaag cctatgttag atgtagaagc gattcgcaag gattttccaa
     4801 ttttagatca gattgtcaat gatgaacctc tggtctatct ggacaatgct gcgacgacac
     4861 aaaaacccct agtagttctg aaagctatta acagttacta tgagcaggac aatgccaatg
     4921 ttcaccgtgg tgtccatacc ttagcggaac gagcgacagc ttcttatgaa gctgctcgtg
     4981 aaaccattcg taagtttatt aatgcaggct ctacaaagga agttctcttt accagaggaa
     5041 cgacaaccag ccttaactgg gtggcacgct ttgctgagga aattctcact gagggagacc
     5101 aggtcttgat ttcagtaatg gaacaccatt ctaatatcat tccatggcag gaagcttgtc
     5161 gaaagactgg agcagagctt gtctatgtct atcttaaaga cggtgccttg gatatggagg
     5221 atttgcgagc taaattgact gataaggtta aatttgtttc cctagctcat gcctccaatg
     5281 ttcttggtgt gatcaatccg atcaaggaaa tcactcaatt agcccaccaa gttggggcaa
     5341 tcatggtagt ggatggtgct caatctacac ctcatatgaa gattgatgtc caggacttgg
     5401 atctggactt tttcgccttt tcgggtcaca agatggctgg tccgactggt atcggtgtcc
     5461 tttacggcaa agaaaagtat cttgagcaaa tgtctccagt agaatttggc ggcgagatga
     5521 ttgattttgt ctacgagcaa tttgctagtt ggaaggaatt gccttggaaa tttgaggctg
     5581 gaacgccaaa tatggcagga gctattggac ttgcgactgc agttgattat ttggaaaaga
     5641 ttggtatgga tgccgttgaa gctcatgaac aggaattgat tgcgtacgtc tatccaaaac
     5701 tgcaggcaat tgagggattg accatttacg gttctcagga tttggctcaa cgttcgggtg
     5761 ttattgcctt taacctaggt gatctccatc ctcacgatct tgcgacggct ctggattatg
     5821 aaggagtggc tgttcgtgct ggtcaccatt gtgcgcaacc cttgcttcag tatttggaag
     5881 tcccagcaac agctcgtgca agtttttata tctacaatac caaggcagat tgcgacaaac
     5941 tagtcgatgc cctacaaaag acaaaggagt ttttcaatgg cactttctaa actagatagc
     6001 ctttatatgg cagtggtagc agaccattcg aaaaatccac atcaccaagg gaagttagaa
     6061 gatgctgagc aaatcagtct caacaatccg acttgtgggg atgtcatcaa cctctctgtc
     6121 aagtttgatg cagaggaccg tttggaagat attgcttttc taaattcagg atgcacgatt
     6181 tcaactgctt ctgctagtat gatgacagat gccgttttag gaaaaaccaa acaagaaatt
     6241 ttagaactgg cgactatttt ttctgaaatg gttcaagggc aaaaagatga gcgtcaagac
     6301 caacttggag acgcggcatt cttgtcaggt gttgccaaat tccctcaaag aatcaagtgt
     6361 gcaaccctag cttggaatgc ccttaagaaa acaattgaaa atcaagaaaa acagtaagac
     6421 aagtttcttt tgtcttatga attattagaa atgaagaaag aaaggatatt atggctgaag
     6481 aaagagtaga accaaaacca attgaccttg gtgaatataa atttggtttc catgacgatg
     6541 tagagcctgt cttatcgaca ggaaaaggac tcaacgaagg tgttattcgt gaattatctg
     6601 ctgctaaggg tgagcctgag tggatgttgg agttccgttt gaagtcttat gaaaccttca
     6661 aaaaaatgcc catgcaaact tggggagcag acttgtcaga gattgacttt gatgacttaa
     6721 tctactacca aaaaccatct gacaaaccag cccgttcttg ggatgatgta cctgaaaaga
     6781 ttaaagaaac ctttgaacgt atcgggattc cagaagctga acgtgcttat ttagcagggg
     6841 cttctgccca gtacgagtca gaagtggttt accacaacat gaaggaagag ttccaaaaat
     6901 taggtattat ctttacagat acagattccg cactcaagga atacccagac ttatttaatc
     6961 aatactttgc gaagttggta ccgccgacag ataacaagtt ggcagccctc aactcagcag
     7021 tatggtcggg tggaactttt atctacgtgc caaaaggtgt caaggtagat attccacttc
     7081 aaacttattt ccgtatcaat aacgaaaata taggtcagtt cgaacgtacc ttgattatcg
     7141 ttgatgaggg agcaagcgtc cactacgtag aaggatgtac agcaccaaca tattcaagca
     7201 atagcttaca cgctgccatt gtagaaattt ttgctttgga cggagcttat atgcgttata
     7261 caactatcca aaactggtct gataacgtct ataacttggt aacaaagcgt gctaaggctc
     7321 aaaaggatgc cactgttgag tggattgatg gaaacttggg tgccaaaacg actatgaaat
     7381 atccatctgt ttaccttgat ggagaaggag cgcgtggtac catgctctct atcgcctttg
     7441 ctaatgcagg gcaacaccaa gacacgggtg ctaagatgat tcacaatgct ccacatacca
     7501 gctcgtctat tgtgtctaaa tccatcgcta aaggtggagg aaaggttgac taccgtggac
     7561 aagtcacctt taacaagaac tctaagaaat ctgtttccca cattgaatgt gataccatta
     7621 tcatggatga cttgtcagca tcagatacta ttccatttaa tgaaattcac aactcgcaag
     7681 tggctttgga acacgaagcc aaagtatcta agatttcaga agagcaattg tattatctca
     7741 tgagccgtgg attgtcagaa tctgaggcaa ctgaaatgat tgtcatggga tttgtagaac
     7801 cctttacaaa agaacttcca atggaatacg cagttgagct gaaccgcttg attagctatg
     7861 aaatggaggg atcagttgga taaaatttga ttttatactc ttcgaaaatc tcttcaaacc
     7921 acgtcagcat cgccttaccg tatgtatggt tactgacttc gtcagtttca tctacaacct
     7981 caaaacagtg ttttgagcaa cctgcggcta gcttcctagt ttgttctttg attttgaaga
     8041 tgaacttgta tcaaaaaatc gcggtttaaa atcgcgattt tttataattt ctcgttaaca
     8101 aagcggacaa actgattcca ccaaactttt aagaagaagg ctttttcaat tttcttgtct
     8161 gctaccattt cgaaactagg gcgctctgtg gtgatgtaac cttgaccaat caagtccttg
     8221 tcttcataag tcaaatggcc aaccactgtt ccagcttcaa gtggtgctgg gattgctttg
     8281 gaatcaggtg tgaattgaac agattgggaa gattgattcc caacacgttc tattagatag
     8341 atatcctctg gagccactgc agttactgta tcttcttttc catcttgtac aggggttttg
     8401 ctatcttgat aggcatcgcc ttgttgaacg attttgcgaa gtgtaaatgt agaagaaata
     8461 taatccatta gggaagatgt agctgtaaat cgagcgtaag gattattgtc ttgatgatct
     8521 gcatttaaaa caactgtgat gactctcatg cctttttcga cagtagtacc aacaaaagac
     8581 tctccagcct tatctgttgt tcctgttttt agcccatcaa aaccaccacg gtaagcaggc
     8641 ataccttcta acatgtagtt ggttgaagtg attgtcatcc cagcaaaagt agaagaaggt
     8701 tttttggtga tttctaagac ttgtgggtat tttttgatga ggttgcgagc aacgatagcg
     8761 acatcataag cactaagctt attttcctca tcttttttag aacctgggta aatgttatcc
     8821 cctagagttt cattgttaag acctgtcgta ttgacaacag tggcatcctg aattccccat
     8881 tccaagagtt ttgcccgcat catatcgacg aaatcttttt ctgagccagc aattttctca
     8941 gctagggcaa tagcggcgct gttggcacta gataccagag ttgcttcaag caactcttcg
     9001 acagtataat tacgggcctc cataggaata ttactggctt cagaatttgt cgtcaattga
     9061 taaggataat cagaaatatc tacaggagtg gagagggtaa tacttccgtt ttccaaagct
     9121 tcatagacca gataaacagt aatcaatttt gttatggaag caatttcgac aggttgcgtt
     9181 gcatccttct catagagaat tttaccagta tttgcctcaa cagcaatcgc atgtttagcg
     9241 gcaatggtaa aatcttgagc aacagcagta gaagcacccc ctaaaagaga gacagttaac
     9301 aaagttaaaa atattttttt catagtagtc ttattctatc ataaagaaaa aaaatattct
     9361 tgctttaata attcatctgt taagcttttt gaaaatatgg taaaataaag tgagggaggt
     9421 aactcatgtt tcgtagaaat aaattatttt tttggaccac agaaatttta ctcttaacca
     9481 tcatctttta cctatggaga cagatgggat ctttgattaa cccttttgtt agcgtgctta
     9541 atacaattat gattccattt ttattagggg gctttcttta ttatttgaca aaccctattg
     9601 ttactttctt aaataaagtc tgtaaactca atcgtttgct tggtatttta attaccttgt
     9661 gtactttggt ctggggaatg gtcataggtg ttgtctatct cttacctatt ttgattaatc
     9721 agttatctag tttgattata tctagtcaaa ctatttatag tcgagtacaa gacttaatca
     9781 tagacttatc taattatcct gcgctccaga atttggatgt agaagctaca attcagcagt
     9841 taaacttatc ctatgttgat attcttcaaa atatcctaaa tagcgtatca aatagtgtgg
     9901 ggagcgtctt gtcagctctt atcagtactg ttttgatttt gattatgact ccagtttttt
     9961 tggtttattt cttattagat ggacataaat tcttgcccat gcttgaaaga acgattctaa
    10021 agagggatcg cttgcatatt gcaggcttat taaagaattt aaatgcgacg attgctcact
    10081 atattagtgg agtttcgatt gacgcaatca ttataggttg tttggcttat attggctata
    10141 gtattattgg tttaaaatat gctttagttt ttgccatttt ttctggtgta gccaatttaa
    10201 ttccttatgt ggggccaagt attggtttga ttcctatgat catcgcaaat atattcactg
    10261 atccccatag actgctgatt gcagtgattt atatgcttgt tgttcagcag gtagatggca
    10321 atatcttata tcctcgaatt gtaggaagtg ttatgaaggt tcatccaatc acgattttag
    10381 ttttactttt gttgtcaagc aatatctatg gtgtagttgg aatgattgtc gcagtgccaa
    10441 cctattctat cttgaaagaa atttctaagt tcttatcccg tttgtatgaa aatcataaaa
    10501 taatgaaaga acgagaaaga gaattagcta agtaaaagtc aggagaaccc tgatttttct
    10561 ttactggaag tggcctttag attagaagac tgaaaataag ttaaagtctt aaactaattt
    10621 tcacagctaa gaatagtaga agttaatctg ataaaaatcg aaaaaaccag tggaattccg
    10681 tgtcagggta agttccactg gttttcatag tctattaaag ttcgaatgaa acctatttat
    10741 aatatattga aactagaata gtacacctct aattctaaaa cattgttaga aatcgatttg
    10801 actgtcctga tctattcgta ctattcttat ttcattttac tatattttgg tgcaataagt
    10861 gaaaagtagt ccgaataata taaggattga ttttatagtt tttaaactca aatgaattaa
    10921 aataaagaga gtacgaaaat tctcatctga aagtatttta gaataattct cttcgtgaat
    10981 ttcttcaaaa cagatagctt catcttaggt atgtgttaat tggatttcgt aagctctatt
    11041 tacaatcgta aagttatgca ctgagaaagt tgtagttagt cttccagttt gctaaatttc
    11101 tcgaatagta tcttttttag gtatgtgatt tctttttgca tttttgagtt agataaggta
    11161 taatggtttt attgtctttt ggggtcgtta cggattcgac aggcattatg aggcatattt
    11221 tgcgactcgt gtggcgacgt aaacgctcag ttaaatataa ctgcaaaaaa taacacttct
    11281 tacgctctag ctgcctaaaa accagcaggc gtgacccgat ttggattgct cgtgttcaat
    11341 gacaggtctt attattagcg agatacgatt aagccttgtc tagcggcttg ataagagatt
    11401 gatagactcg cagtttctag acttgagtta tgtgtcgagg ggttgttaaa ataatacata
    11461 acctatggtt gtagacaaat atgttggcag gtgtttggac gtgggttcga ctcccaccgg
    11521 ctccattatt cctttgcatt cttttgcatt ccttggtaaa acgttgttaa atcaacgttt
    11581 tttattttta tctttggtat tcctttgcat tcttttgcta aaaagggagt cacaaacaga
    11641 ccctatttta aaaaaaggat agaaaaaagg atacaacatt tgtcgcatcc tagaaataat
    11701 cttttttcga cggaagacat gggattcgaa cccacgcacg ctattacacg cctaccgcgt
    11761 ttccaacacg gcctcttaag cctcttgagt aatcttccaa tacttactca aatagtctac
    11821 cataaaggct cttatcttgc aataaaaatt ctagaaataa gaaaaaatga tagattttga
    11881 aagaaaatga taaaaaatgc ttgacttcga aagaaagtat gatagaatga atagtgtaaa
    11941 cgataacagg aggtgattca gtgttaaaaa cagaacgtaa acaactaatt ttagaggagt
    12001 taaatcaaca tcatgtagtt tctctagaaa aattagttag tttgctagaa acgtcagaat
    12061 caacggttcg aagagacttg gatgagttgg aagcggaaaa caagcttcgt cgtgtgcatg
    12121 gtggagcaga actcccccac tccttacagg aagaagaaac cattcaagaa aaatctgtca
    12181 aaaaccttca agaaaagaag ttgctggctc agaaagcagc ctctctcatt aaagaaaaag
    12241 atgtcatctt tatcgatgct ggaacaacaa ctgctttttt gattcatgaa ttggtcaata
    12301 agaatgttac agttgtgacc aactccattc accatgccgc tcagttggtt gaaaagcaga
    12361 ttccaactgt catggttgga ggaaacgtca agacggcgac agatgctagt atcgggggcg
    12421 ttgctcttaa ccagattaac caattgcact ttgaccgtgc ctttatcgga atgaatggtg
    12481 ttgacgatgg ctattatacg actcctgata tggaggaagg agctgtgaaa agagctattt
    12541 tggagaatgc caagcagacc tacgtcttgg tggattcgtc aaaaattgga caaacttgct
    12601 ttgccaaggt agcaccactc aaacgcgcta tcgttatcac tagtcaaggg catgagctct
    12661 tgcaggttat taaggagaaa acggaggtaa tagaagtatg atttatacag tcacactcaa
    12721 tccatccatt gactatatcg ttcgtttgga ccaagtcaaa gttggtagtg taaatcgtat
    12781 ggacagtgat gataagtttg ctggtgggaa aggaatcaat gtcagccgtg tcttgaaacg
    12841 tttgaatata ccaaatacag cgacgggatt tatcggtggc tttactggta aatttatcac
    12901 agatacttta gcagaggaag aaatcgagac acgttttgtc caggtggcag aagatactcg
    12961 tatcaatgtt aaaatcaaag cagaccaaga aacagaaatc aacggaacgg gtccaactgt
    13021 tgaaccggtt cagctagaag aattgaaagc tattttatct agtctgacag cagaagatac
    13081 agttgtcttt gcaggttcaa gtgctaaaaa tctaggcaat gttatctata aggatttgat
    13141 ttccttgacg cgccagactg gtgcgcaagt ggtctgtgac tttgaaggac agaccttaat
    13201 tgatagtttg gactaccagc ctcttcttgt aaaaccaaac aatcatgaac ttggagcgat
    13261 ttttggggtt aaactcgaaa gtttagatga aattgagaaa tacgctcgtg agttactggc
    13321 taagggtgct caaaatgtta ttatctctat ggctggtgat ggcgcccttc ttgtcacatc
    13381 tgagggagct tacttcgcta aaccaatcaa aggaacagtc aaaaattcag ttggagctgg
    13441 tgattctatg gttgctggat tcacaggtga atttgtcaaa tcaaaagacg cagtagaagc
    13501 cttcaaatgg ggagtggctt gcggaacggc aactaccttc tcagatgact tggcaacggc
    13561 ggaatttatt aaagaaacat atggaaaagt tgaggtagaa aaaagatgaa aattcaagac
    13621 ctattgagaa aagatgtcat gttgctagat ttgcaggcaa ctgaaaaaac agctgtcatc
    13681 gacgagatga ttaaaaattt gacagagcac agttatgtaa cagattttga aacatttaaa
    13741 gaaggaattt tggcgcgtga agctttgact tctactggtt tgggtgatgg aatcgcaatg
    13801 cctcacagca aaaacgctgc tgtcaaagaa gcgacagttc tatttgctaa gtcaaataag
    13861 ggtgttgact acgagagctt ggatggacaa gcaactgacc tcttcttcat gattgcagct
    13921 ccagaaggtg ccaatgatac tcacttggca gccttggcag aattgtctca atacttgatg
    13981 aaagacggtt ttgcagacaa acttcgtcaa gcaacatctg cagaccaagt tatcgaactt
    14041 tttgaccaag cttcagaaaa aactgaggaa cttgttcaag tacctgctaa tgactctggt
    14101 gactttatcg tagctgttac agcttgtaca acaggtattg cccacactta catggcccaa
    14161 gaagcccttc aaaaagtagc tgctgaaatg ggggttggta tcaaggtcga aaccaacggt
    14221 gctagcggtg ttggaaatca actaactgca gaagatatcc gtaaggctaa agctattatc
    14281 attgcagcag acaaggccgt tgaaatggat cgatttgatg gaaaaccatt gatcaatcgt
    14341 ccagttgctg acggtatccg taagacagaa gagctaatta acttggctct ttcaggagat
    14401 actgaagtct accgtgccgc taatggtgca aaagctgcaa cagcctctaa cgaaaaacaa
    14461 agccttggtg gtgccttcta caaacacttg atgagtggtg tatctcaaat gttaccattc
    14521 gttatcggtg gtggtatcat gattgccctt gccttcttga ttgacggtgc tttgggtgtt
    14581 ccaaatgaaa accttggcaa tcttggttct taccatgagt tagcttctat gttcatgaaa
    14641 attggtggag ctgcctttgg tttgatgctt ccagtctttg cgggttatgt tgcctactct
    14701 attgctgaaa aaccaggttt ggtagcaggt ttcgtggctg gtgctattgc caaagaaggt
    14761 tttgcctttg gtaaaattcc ttatgccgca ggtggtgaag caacttcaac tcttgcaggt
    14821 gtctcatctg gtttcctagg tgcccttgtt ggtggattta tcgcaggtgc cttggttctt
    14881 gccatcaaga aatacgttaa agttcctcgt tcactcgaag gtgctaaatc aatccttcta
    14941 ttgccacttc ttggaacaat cttgacagga tttgttatgc tagctgtgaa tatcccaatg
    15001 gcagcaatca acactgctat gaatgacttc ctaggcggtc ttggaggagg ttcagctgtc
    15061 cttcttggta tcgtccttgg tggaatgatg gctgttgaca tgggtggacc agttaataaa
    15121 gcagcttatg tctttggtac aggtacgctt gcagcaactg tttcttcagg tggttctgta
    15181 gccatggcag cagttatggc tggaggaatg gtgccaccac ttgcaatctt tgtcgcaact
    15241 cttcttttca aagataaatt tactaaggaa gaacgtaact ctggtttgac aaacatcatc
    15301 atgggcttgt catttatcac tgagggagcg attccatttg gtgccgctga cccagctcgt
    15361 gcgattccaa gcttcatcct tggttcagca gtagcaggtg gactcgttgg tcttactggt
    15421 attaaactca tggcgccaca cggaggaatc ttcgttatcg cccttacttc aaatgctctc
    15481 ctttacctcg tttctgtctt ggtaggagca atcgtaagtg gtgtggttta tggttaccta
    15541 cgcaaaccac aagcataaaa aatagaaaaa tgaaaagatt ggaccgtttg gtgcagtctt
    15601 tttctctttc cgaaatgcct gtgaaatatg gtataataga agaatggcaa acaagaatac
    15661 aagtacaaca agacggagac cgtctaaagc agaactggaa agaaaagaag cgattcaacg
    15721 aatgttgatt tcgttaggaa ttgcgatttt attgattttc gcagccttca aattaggggc
    15781 tgcaggtata accctttata atttaattcg cttgctagtg ggtagcctag cttatctggc
    15841 gatattcggc ctattaatct atctcttttt tttcaagtgg atacgaaaac aggaaggact
    15901 cttatctggc tttttcacca tatttgctgg cttactcttg atttttgaag cctacttggt
    15961 ttggaaatat ggtttggaca agtccgttct aaaagggacc atggctcagg ttgtgacaga
    16021 tctgactggt tttcgaacga ctagttttgc tggagggggc ttgatcgggg tcgctcttta
    16081 tattccaaca gcttttctct tttcaaatat cggaacttac tttattggtt ctatcttgat
    16141 tttagtgggt tctctcctag tcagcccttg gtctgtttac gatattgctg aatttttcag
    16201 tagaggcttt gccaaatggt gggaagggca cgagcgtcga aaagaggaac gctttgtcaa
    16261 acaagaagaa aaagctcgcc aaaaggctga gaaagaggct agattagaac aagaagagac
    16321 tgaaaaagcc ttactcgatt tgcctcctgt tgatatggaa acgggtgaaa ttctgacaga
    16381 ggaagctgtt caaaatcttc cacctattcc agaagaaaag tgggtggaac cagaaatcat
    16441 cctgcctcaa gctgaactta aattccctga acaggaagat gactcagatg acgaagatgt
    16501 tcaggtcgat ttttcagcca aagaagccct tgaatacaaa cttccaagct tacaactctt
    16561 tgcaccagat aaaccaaaag atcagtctaa agagaagaaa attgtcagag aaaatatcaa
    16621 aatcttagaa gcaacctttg ctagctttgg tattaaggta acagttgaac gggccgaaat
    16681 tgggccatca gtgaccaagt atgaagtcaa gccggctgtt ggtgtaaggg tcaaccgcat
    16741 ttccaatcta tcagatgacc tcgctctagc cttggctgcc aaagatgtcc ggattgaagc
    16801 accaatccct gggaaatccc taatcggaat tgaagtgccc aactccgata ttgccactgt
    16861 atctttccga gaactatggg aacaatcgca aacgaaagca gaaaatttct tggaaattcc
    16921 tttagggaag gctgttaatg gaaccgcaag agcttttgac ctttctaaaa tgccccactt
    16981 gctagttgca ggttcaacgg gttcagggaa gtcagtagca gttaacggca ttattgctag
    17041 cattctcatg aaggcgagac cagatcaagt taaatttatg atggtcgatc ccaagatggt
    17101 tgagttatct gtttacaatg atattcccca cctcttgatt ccagtcgtga ccaatccacg
    17161 caaagccagc aaggctctgc aaaaggttgt ggatgaaatg gaaaaccgtt atgaactctt
    17221 tgccaaggtg ggagttcgga atattgcagg ttttaatgcc aaggtagaag agttcaattc
    17281 ccagtctgag tacaagcaaa ttccgctacc attcattgtc gtgattgtgg atgagttggc
    17341 tgacctcatg atggtggcca gcaaggaagt ggaagatgct atcatccgtc ttgggcagaa
    17401 ggcgcgtgct gcaggtatcc acatgattct tgcaactcag cgtccatctg ttgatgtcat
    17461 ctctggtttg attaaggcca atgttccatc tcgtgtagca tttgcggttt catcaggaac
    17521 agactcccgt acgattttgg atgaaaatgg agcagaaaaa cttcttggtc gaggagacat
    17581 gctctttaaa ccgattgatg aaaatcatcc agttcgtctc caaggctcct ttatctcgga
    17641 tgacgatgtt gagcgcattg tgaacttcat caagactcag gcagatgcag actacgatga
    17701 gagttttgat ccaggtgagg tttctgaaaa tgaaggagaa ttttcggatg gagatgctgg
    17761 tggtgatccg ctttttgaag aagctaagtc tttggttatc gaaacacaga aagccagtgc
    17821 atccatgatt cagcgtcgtt tgtcagttgg atttaaccgt gcgacccgtc tcatggaaga
    17881 gcttgagatg gcaggtgtca ttggtccagc tgaaggtacc aagccaagaa aagtattgca
    17941 gcaataaaaa atagcttctt tccaaggttg gaaggagcta ttttactggc tattgattac
    18001 ttttatactc ttcgcaaatc tcttcaaacc acgtcagctt cgccttgccg tactcaagta
    18061 ctgtctacgg ctagcttcct agtttgctct ttgattttca ttgagtatta ttttctgaag
    18121 ttggagtatt gggctgtttt tcattttcag tggcaggttt acttgtagca ggtgtagtag
    18181 agtcctgagt tgctgttttc tgatcttctt ttttctcttc cttgacgcta gattttggcg
    18241 tttcttcttg ttgtgttttt tcttgagaag tgttattttc cttatttgga gtagtatttt
    18301 cctgagggga ttctttttga atttctttga caaaggttgt cgtctggctt gtcgtaggtt
    18361 cttttttagt atttttatta ttattattat ccaaggcgtt catgatcgtg atacccgcgg
    18421 taatcaaacc aaggatacta ccgatagtag taatggtttt ttgaaaaaca gtaaagcctt
    18481 ttttgatatg ttctgttttc ggttttgaag ttctacgata gttagacata cattctctcc
    18541 tttgattatg atttattata ctctgtttct ttaaaaaaat cttaaaaaaa gagaaattgc
    18601 cctttcttgt cgcaggctcc gtttcatgat acaatagaag gagtgatttt agaaagcgtg
    18661 agaaacatga tttactttga taattcggcg acgaccaggc cctatccaga agcccttgaa
    18721 acctatatgc aggtggcttc aaaaatttta ggaaatccat ctagtctcca tcgtttggga
    18781 gaccaggcaa cacgaatttt agatgcttcc cgtcaacaga ttgcagattt aatcggtaag
    18841 aaaagtgatg aaatcttctt tacatctggt gggacagaag gggataactg gatcatcaag
    18901 ggagtagcat ttgaaaaagc ccagtttggc aagcacatca tcgtatcagc cattgaacat
    18961 ccagcagtta aggaatcagc cctctggttg aaagctcaag gttttgaagt ggattttgct
    19021 ccagttgata acaaaggatt tgtggatgtt gaggcgctag aagatttgat aagacctgat
    19081 acgaccctcg tttccatcat ggctgtgaac aatgaaatcg gctctatcca acctattgag
    19141 gctatttcag aattcttggc agacaagcca actatttcct tccacgttga tgcggttcag
    19201 gcgcttgcca agattccgac tgaaaagtat ctgacagaac gagtggattt cgcgactttc
    19261 tctggtcaca agttccacgg aatccgtggt gttggtttta tctatatcaa gtctggcaag
    19321 aagattacgc ctcttttaac aggtggtggt caggaacgtg attaccgttc gacaactgaa
    19381 aatgtggcag gaattgcagc gaccgctaag gctctccgtt tatctatgga aaagctagat
    19441 atctttagga gcaagactgg gcagatgaag gcagtgattc gtcaagcact tctggactat
    19501 ccggatatat ttgtcttttc agatgaggaa gacttcgccc ctcatattct gacttttgga
    19561 atcaagggtg ttcgtggtga ggtcattgtt cacgcctttg aagactatga tattttcatc
    19621 tcaacgacct cggcttgttc gtccaaggct gggaaaccag ccggaaccct gattgctatg
    19681 ggagtggaca aggataaggc tcagtcagct gtgcgtctta gtctagacct tgaaaatgat
    19741 atgagtcagg tcgagcagtt cttgaccaag ctaaaattaa tttacaatca aactagaaaa
    19801 gtaagatagg agcattcatg cagtattcag aaattatgat tcgctacggt gagctgtcaa
    19861 ccaagggcaa aaatcgtatg cgtttcatca ataaacttcg caataatatt tcagacgttt
    19921 tgtctatcta tccccaagtt aaggtaacag cagatcgcga ccgtgcccac gcttacctca
    19981 atggagcaga ttacacagca gtagcagaat cgctcaaaca agtatttgga attcaaaact
    20041 tttcccctgt ttataaggtt gaaaaatctg tagaagttct gaagtctgct gtccaagaga
    20101 ttatgcagga catctacaag gaaggcatga cctttaaaat ctctagcaag cgtagcgacc
    20161 acacctttga attggacagt cgtgaactca accaaacgct tggaggggct gtattcgaag
    20221 ccattccaaa cgtacaagct caaatgaaaa gtcctgacat caatcttcag gtggagatac
    20281 gtgaagaagc agcctatctt tcttatgaaa ccgttcgagg ggcaggtgga ttaccagtgg
    20341 gaacttctgg taagggcatg ctcatgttgt cagggggaat cgattcccct gtagctggct
    20401 atctagcgct taaacgaggg gtagatatag aggcagttca ctttgccagc ccaccttaca
    20461 cgagtcctgg tgctcttaaa aaagcccaag atttgacccg taaattaacc aaatttgggg
    20521 gaaatatcca gtttatcgaa gttcctttta cagagattca agaggaaatc aaagccaaag
    20581 cgccagaagc ctaccttatg accttgacgc gtcgttttat gatgcgtatt actgaccgta
    20641 ttcgtgaggt acgaaatggt ttagttatca tcaatgggga aagtctaggt caagtagcca
    20701 gccaaaccct tgaaagtatg aaggctatca atgctgttac caacactccc atcattcgtc
    20761 ctgtggttac catggacaag ttggaaatca ttgacatcgc ccaggaaatc gatacctttg
    20821 acatttcaat ccaaccgttt gaagactgtt gtactatttt tgcaccagat cgtccaaaaa
    20881 caaatcctaa aattaagaat gcggagcagt acgaagcgcg tatggatgtt gaaggcttgg
    20941 ttgagcgagc agtggctgga atcatgatta ctgaaatcac acctcaagcc gaaaaagatg
    21001 aagttgatga cttgattgac aatctgctct aattcagaaa atccaaaaga atagcgaaaa
    21061 tcagtaaaaa aagttagttt tttctctaaa aacaggtaaa aaactaactt tttttatttt
    21121 tatgatataa tgatataaaa ttttgaatat agagagtttt ctgacaatga atcaatccta
    21181 cttttatcta aaaatgaaag aacacaaact caaggttcct tatacaggta aggagcgccg
    21241 tgtacgtatt cttcttccta aagattatga gaaagataca gaccgttcct atcctgttgt
    21301 atactttcat gacgggcaaa atgtttttaa tagcaaagag tctttcattg gacattcatg
    21361 gaagattatc ccagctatca aacgaaatcc ggatatcagt cgcatgattg tcgttgctat
    21421 tgacaatgat ggtatggggc ggatgaatga gtatgcggct tggaagttcc aagaatctcc
    21481 tatcccagag cagcagtttg gtggtaaggg tgtggagtat gctgagtttg tcatggaggt
    21541 ggtcaagcct tttatcaagc acaaaacagg ttggtttgat ggcatgatga cgacaggttg
    21601 ctctatggga gcctatcatg cactcaattt cttcctccag catccagatg tctttaccaa
    21661 agtgattgct ctcagtggtg tttacgacgc acgtttcttt gtcggcgatt actacaacga
    21721 tgatgctatt taccaaaact cgccagtaga ttatatttgg aaccaaaacg atggctggtt
    21781 tattgaccgt taccgtcagg cagagattgt gctgtgtacg gggcttggag cctgggaaca
    21841 agatggttta ccatcctttt acaagctcaa agaagccttt gaccagaaac aaattccagc
    21901 ctggtttgct gaatggggac atgatgtcgc ccacgactgg gaatggtggc gtaaacaaat
    21961 gccttatttc ctcggtaatc tctatttata aaaggagtta cctatgaatt accttgttat
    22021 ttctccctac tatccacaaa actttcaaca gtttaccatc gaactagcta ataaaggcat
    22081 cacagtcttg ggaattggtc aagagtctta cgagcaattg gatgagccct tgcgcaatag
    22141 cttgaccgag tattttcgtg ttgataatct tgagaacata gatgaagtca aacgtgcagt
    22201 tgcttttctc ttttataaac atggtccaat tgaccgcatc gagtctcaca atgaatactg
    22261 gcttgagcta gacgcaacac tcagagaaca attcaatgtt tttggtgcca aaccagagga
    22321 tctcaaaaag acgaaatata agtctgaaat gaagaaactt ttcaaaaaag caggtgttcc
    22381 tgtggtacct ggagctgtta tcaagacgga agcagatgtt gatcaagcag tgaaagaaat
    22441 cggtcttcca atgattgcca aacctgataa tggagtggga gcagccgcaa cctttaaact
    22501 tgagacagaa gacgatatca atcacttcaa gcaagaatgg gaccattcaa ccctttattt
    22561 ctttgaaaaa tttgtcactt ccagcgaaat ctgtaccttt gacgggctcg tggacaagga
    22621 tggaaagatt gtcttctcaa caacctttga ctacgcctat acaccgcttg acctcatgat
    22681 ttataagatg gacaattctt attatgtgct caaggatatg gatcctaaac tgcgcaagta
    22741 tggggaagca attgtcaaag aatttggtat gaaagaacgg tttttccata ttgagttctt
    22801 ccgtgagggg gacgattata ttaccatcga gtacaataac cgccctgcag gtggttttac
    22861 cattgatgtt tataactttg ctcattcctt ggacctttat cgtggctatg cagctattgt
    22921 cgcaggagag gagttcccgg cgtcagactt tgaaactcag tattgtttgg ctacttctcg
    22981 ccgtgcaaat gctcactatg tttattcaga agaggatttg cttgccaaat atagccagca
    23041 gttcaaggtt aaaaaagtca tgccagctgc cttcgcggaa cttcaaggag attacctgta
    23101 tatgctgaca actccgagtc gacaagaaat ggatcagatg attgctgatt tcggacaacg
    23161 tcaagaataa gaactatcgg attaaggaaa ttcactccct taatcctttt gttttgtctg
    23221 gtaaaaaata agagcatcct aacaaggtag ctatcataaa acttgttcga taactatttg
    23281 aagcaggatt aggtggctag aaattgaatt ttaacatttc aatttagtca tagtattgtg
    23341 ttttcgtatc cttaaatcag ctaaaaggat ccatgacgac acctatacga tatagttttc
    23401 aggataccaa accagtctat taatactcaa tgaaaatcaa agagcaaact aggaagctag
    23461 ccgcaggttg ctcaaaacac tgttttgagg ttgtggatag aactgacaga gtcagtatca
    23521 tatacctacg gcaaggtgaa gctgacgtag tttgaagaga ttttcgaaga gtataaatct
    23581 tattgatgaa ctgcttgcag tctgagaaaa aatgagcttg gatattattt ccaaactcac
    23641 ttaaagtcaa tttcaatcca ctagaacaag cctagtacag ttccatcgct ttcaacatcc
    23701 atgttgagag ctgctggacg ttttggaaga cctggcatgg tcataacatc accagttaag
    23761 gcaacgatga agcctgcacc taattttggt accaattcac gaatggtaat ttcaaagttt
    23821 tctggtgctc caagcgcatt tggattgtct gagaaactgt attgagtttt agccatacag
    23881 attggcaatt tgtcccaacc gttttgaacg atttgagcaa tttgtgtttg agatttcttc
    23941 tcaaagttca ctttgctacc acgatagatt tcagtgacaa ttttttcaat cttttcttgg
    24001 acagaaaggt cattatcata caaacgttta tagttagctg gattttcagc aattgtctta
    24061 acaactgttt cggcaagtgc tactccacct tctgctccat cagcccagac actagccaat
    24121 tcaactggta catcgattga ggcacagagt tcttttaaga ctgcaatttc agcttctgta
    24181 tcagatacaa attcgttaat agctacaact gctggaatac cgaacttacg gatattttca
    24241 acgtggcgtt tcaagttagc aaaacctgca cgaactgcct ctacattttc ttcagtcaga
    24301 gcgtctttag ccacaccacc attcatctta agggcacgaa gggttgcgac aataacaact
    24361 gcatctggag atgttggcaa gtttggtgtc ttgatatcaa ggaatttctc agcaccaagg
    24421 tccgcaccaa aaccagcttc agtaacagtg taatcagcca agtgaagggc tgttgtcgtc
    24481 gccaaaacag agttacagcc atgagcgata ttggcaaatg gaccaccgtg tacaaaggca
    24541 ggtgtaccgt aaattgtctg aaccaagttt ggcttaatag catccttcaa aatcaaagcc
    24601 aaggcaccct caacctgcaa atcacctaca gaaacaggcg tacggtcata gcgataacca
    24661 ataacgatat tcgccaaacg acgtttcaag tcctcgatgt ccgttgccaa gcaaagaatt
    24721 gccatgattt ctgaagcaac tgtaatatca aaaccgtcct cacgtggaat accgtttaga
    24781 ggaccaccaa gaccaacagt cacatggcgg agcgcacggt cgttcaagtc cacaacgcgt
    24841 ttccagagga tacgacgttg atcaattccc agctcattcc cttggtgcaa gtggttgtca
    24901 atcaaggcag aaagggcatt gttggcagtt gtaatagcat gcatatctcc agtaaagtgg
    24961 aggttgatgt cttccattgg cagaacttgt gcatacccac caccagcagc accacccttg
    25021 atccccatga ctggaccaag agacggttcg cggatagcaa tcatggtttt cttgccaatc
    25081 ttgttcaagg catccgcaag accaatggta agcgtcgact ttccttcacc tgcaggtgtt
    25141 gggttgatgg cagtaaccaa gatcaattta ccgactggat tgctctcaac tgcacgaatt
    25201 ttatcaaagc tgagtttagc cttgtacttt ccgtacaact ccaaatcgtc gtaagaaata
    25261 ccaagtttct ctacaacatc aacaattggc ttcaactcaa tactctgtgc gatttcaata
    25321 tctgttttca ttcaaaattc ctctaacctc ttatatgata attcattata tcacaaaaca
    25381 agatttttaa catcctaaaa ctctctaaac gttcgtaaat atctctgttt ttaaggcttt
    25441 tagaatcctt tcttaaattt tatatggctt tatagtttga aactatagta aatcttcgtt
    25501 tttaccaaaa atttatcact ttcattttac ttaccgctta tttttgtgta caatagtgct
    25561 atgaaaattt tagttacatc gggcggtacc agtgaagcta tcgatagcgt ccgctctatc
    25621 actaaccatt ctacaggtca cttggggaaa attatcacag agactttgct ttctgcaggg
    25681 catgaagttt gtttaattac tacaaaacga gctctgaagc cagagcctca tcctaaccta
    25741 agtattcgag aaattaccaa taccaaggac cttctactgg aaatgcaaga acgtgttcag
    25801 tattatcagg tcttgattca ctcaatggct gtatctgact acactcctgt ttatatgacg
    25861 ggactggagg aagttcaggc tagttccaat ctagaagaat ttttaagcag gcaaaatcat
    25921 caagctaaga tttcttcaac tgatgagatt caggttttgt tccttaaaaa gacacccaaa
    25981 atcatctctc tagtcaaaga atggaatcct gctattcatc tgattggttt caaactgctg
    26041 gttgatgtta acgaagacta tctggttgac attgctaaaa aaagtcttat caaaaaccaa
    26101 gcagacttga ttatcgcaaa tgacctcact caaatctcag cgaaccagca tcgtgcaatc
    26161 tttgttgaaa aagatcagct tcaaacagtc cagactaaag aagaaattgc agaactcctc
    26221 cttgaaaaaa ttcaaaccta tcattcatag aaaggaaagc tatggcacat attctcttgg
    26281 ctgtaacggg ctcaatcgcc tcttacaagt cggcagattt agtcagttct ctaaaaaaac
    26341 aaggtcatca tgtcacggtc ttaatgaccc aggctgctac agagtttatt caacctttga
    26401 cactgcaggt actctcacag aattctgtcc acttagatgt catgaaggaa ccctatcctg
    26461 atcaagtcaa tcatatcgaa cttggaaaaa aagcagattt atttatcgtg gcccctgcaa
    26521 ctgctaacac tattgcaaaa ctagcccacg gctttgcgga caacatggta acctgtacgg
    26581 ctctagcatt acccagtcat attcctaaac tcatcgcacc tgctatgaat acaaagatgt
    26641 atgaccatcc agcaactcag gctaatctga aaacattaga aacctacggc tatcagctga
    26701 tcgctcctaa ggaatccctc ctagcttgtg gagaccacgg acgaggagct ttaactgacc
    26761 tcacaattat tttagaaaga ataaaggaaa ctctcgatga aaaaacactc taatattgca
    26821 cccattgcta tcttttttgc aaccatgctc gtgatacact ttctgagctc acttatcttt
    26881 aaccttttcc catttccaat caaaccgacc atcgttcata ttcctgtcat tattgccagc
    26941 attatttacg gtccacgagt tggggttaca cttggatttt tgatgggtct acttagctta
    27001 actgttaaca cgattacaat tctaccgaca agctacctct tctccccatt tgtaccaaac
    27061 ggaaacatct actcagctat tattgccatt gtcccacgta ttttgattgg tttaactcct
    27121 tacttagtct ataaactgat gaaaaacaag actggtctga ttttagctgg agcccttggt
    27181 tccttgacaa atactatttt tgtccttgga ggaatcttct tcctatttgg aaatgtttat
    27241 aatggaaata tccaacttct tctggcaacc gttatctcaa caaattcaat tgctgaattg
    27301 gtcatttctg caattctaac cctagccatt gttccacgac tacaaacctt gaaaaaataa
    27361 aaacaatctc cgctttcaaa cctgaaggtg gagattttgc tctatacagt ttctttttaa
    27421 tgaaatcttt actatagtaa aacgaaataa gaacaggaca aatcgatcag gacagtcaaa
    27481 tcgatttcta acaatgtttt agaagtagag gtggactatt ctagtttcaa tctactataa
    27541 cttttaacta aaaaatgatc tataaaccca agtaaattct tgctttattg tctggtttat
    27601 tgtaccatac tagtgtatat gcagttaaaa aggagattct tgtgaataca cggaaaaaga
    27661 cacaatttat gacaatgaca gcccttttaa cggctattgc gattttgatt ccaattgtta
    27721 tgcctttcaa gattgtcatt ccacctgctt cctatacttt ggggagccac atcgctattt
    27781 ttatagccat gttcttgtcg cccttgatgg cagtttttgt catcctagcc tctagttttg
    27841 gatttttgat ggctggctat cccatggtta tcgtttttcg ggctttttcc catatatctt
    27901 ttggtgcttt aggagctctt tacctacaaa aattccccga taccctagat aaaccaaaat
    27961 cttcctgggt tttcaacttt gttttggctg ttgttcatgc ccttgctgaa gtattagcct
    28021 gtgtcctttt ttacgcaact tcgggtacca atgtagaaaa catgttctat gttctatttg
    28081 tgctagttgg atttggcaca attatccata gtatggtaga ctatacatta gcactagctg
    28141 tctataaagt gcttcgaaaa cgccgttaaa aggaaaagct atgacaaaag atcgcaaaca
    28201 agccctgctc caactcttga aagaagctcc taaagccctt aatggccaaa gtttggcgga
    28261 acattttcat gtcacacgtc aggtcattgt gcaggacatt gcaattttga gagccgatgg
    28321 cgctcctatc ctatccacca atcgtggcta catctataag caaattgata ccaatcctta
    28381 tgttcacaaa cttttcaaag tgaaacatga agttgaagaa atcggtcagg aactccttgc
    28441 tattgtcgat aatggtgggc atgtccagaa taccttgatt gaccatcccg tttatggaga
    28501 aattgaaacc ttgcttaaac tgtcttgtcg cagagatgtg caacattttc tagaacaagt
    28561 cgagcattct gactttagac ctctatctga attgacagat ggcatccatt accacctagt
    28621 cgaagccgaa acacaacaag acctccacta tatcgaggag gccttggatc agctaggtta
    28681 tttagtaaaa gactagaaga ttttcttttc ccaatcgtct tctgtacggc gagggtagaa
    28741 aaactctgac ttgtcgggag cttccatcat ttccatcaat ggtagcatat cataggccag
    28801 atttaagttt ggaatctggt ctttttgcac ccaagaaact tctccctctt ctgaagattg
    28861 aagggtacca gagaactcag tcgccttata acaaatgaca atatagcgcc cacctgtatc
    28921 tagtggccaa tttttaatgc cgacaagttg aggattttgg atagtcaacc ctgtttcttc
    28981 gtagatttca cgaatgacag actccgcaaa agcctcatca ttttctacat gacctccagg
    29041 aaaggcataa ccagaccagc gattgttttc aggggcgcga tactgcatca ccacgcgctg
    29101 agtttcgagg tcttcaatca gacagatatt tgttaaaatt gttaattggg aacgggacat
    29161 aaatttactc gctttctaat ttattaaatt ttcagactta ctaccaaaga tattatcttt
    29221 tactttttaa aattatttag agttgaatac cattcgtttt tcctttatag gctttccaag
    29281 ttcaagtatc ttttcttgtc catcaaaagt aaaacccatt ttttgataga aagcaatggc
    29341 tcgcttgtta tctttcaata cccataagaa aatttcagaa aaacgattca gagcagtcaa
    29401 agctgttttc attaactttt gtgctatgcc ttttccataa tagtctttta aaacatataa
    29461 agcaataatt tcaccagctt gaatagtctc atcacgaaag ttaccataac tgataaaacc
    29521 aactaccttc agatcaccta tcgcaatcaa tgtattttct ggatactttt gactaaagaa
    29581 tcgacatctt tctaatgtca ttgtctcctg aaattctgca ggcaaaaggt catcataagc
    29641 ctctctccac gtttgccagt gaacgaggga tttaccttct atctcttcag gagtttccat
    29701 tgatttgata ataaccgtca tttattttct cccagtcttc tctcaaaata ccatatttaa
    29761 tactatcaaa atatttacct tgataataac gaacttttgg aatatgagct tcttttttca
    29821 ttcttaattt ttcagcaagt ttcatcatac caagatttcc tgaccaagtt gtcaaaccca
    29881 gatgctccaa ctccaagtaa tcctgaaacg tcctatctat ccactgcaac atagcaactt
    29941 tcccaatacc agtgttccag aattttttat cataaatacc aattcccaat tccatccatc
    30001 ttgtttgttt acatacccaa taacgcgaaa cagtcccaac tagtttatca tcaacaaaaa
    30061 taccaaggcg atttgagttg cttaaaatgg attctaattt ttgtagttcg aattctttaa
    30121 aatttgaaaa atactgataa tcatcataat agggagcatc atactgtttc caaactggat
    30181 taagttgtga ataagccatt tcccataaag acatcaaatc ttctctcttt aactttctta
    30241 aataaatcat actattcccc taatccaagg ccttgacttc caacatcata tcacgtatct
    30301 gagctgctag ttcaaagtca agcacttcga cggcttcttg catttgtttt tctagtttct
    30361 tgacgagttc tttgcgctct tgtttgttga ggttattgat gtcgacttcc ttgtcctctt
    30421 ccttagcaac tgccttggtc acggcaatca ggtcacggat ttctttcttg attgtctgtg
    30481 gtacgatacc atgctcttca ttataggcca tctgaatttt ccgacggcgg gcagtttcat
    30541 cgatagcacg ttgcatagac tgggtaaccg tgtctgcata catgatgaca tggccttcac
    30601 tgttacgagc agcacgtcca atggtctgga ttaaaccacg ttcgttacga aggaaacctt
    30661 ccttgtcagc atctagaata gcaaccaagc ttacctcagg aacgtcaatc ccttcacgaa
    30721 ggagattgat tccgaccaag acatcaaaga cacccaaacg caggtctcgg ataatctctg
    30781 tccgttctaa agtcttgata tccgagtgca tgtacttgac cttgatgccc atttctttaa
    30841 agtagtcggt taagtcctct gccattttct tagtcaaggt tgtgataaag gttcgttcgt
    30901 tcttttcaac acgggcattg atttcaccca agaggtcatc aatctgtccc atagtcggac
    30961 ggacctccac ctcaggatcc aaaagacctg tcggacgaat gatttgctca atcactgtct
    31021 cggtctgttc attttcatag tcgcctggtg tcgctgaaac gtaaacaatc tggtgcacat
    31081 ggctttcaaa ttcttcacga cggagaggac gattgtccag tgctgacggc aaacggaaac
    31141 cataattaac cagcatttct ttacgcgaac ggtctccatt gtacataccc ttgatctgcc
    31201 ccatggtcat gtggctctcg tcaatcatga ttaagaaatc atctgggaag aagtcgagaa
    31261 gcgtatatgg aggttctccc tcactccgtc catccatgtg gcgagaataa ttttcaaccc
    31321 cgttggtata gcccatctca cgcagcattt cgatatcata ctctgtccgc tgtttcaaac
    31381 gttgggcttc aagcaatttg ccttccttct caaagatagc taactgttct tccaattctg
    31441 cctgaatctt ggcaatggca acttccatgt ggtcgtcatt ggtcacaaag tgagttgcag
    31501 ggaaaatcgc taaatgatcc acttctccca agacctgacc tgtcagagcc tcaacctcac
    31561 ggatacggtc aatttcgtct ccaaaaaatt ctactcgaaa ggcatgctca tcacgggaag
    31621 ctgggaaaat ttctaccaca tccccacgaa cgcgaaatct tccccgttgg aaatcaatat
    31681 cattacgttc aaactggata tcaaccaagt cattcaagag tttatcacga gaaatttcaa
    31741 gacctggacg gagactaaca acactgtcag cgtattcctt gggcgaaccc aaaccataga
    31801 tacaagagac agaagccacg acgataacat cattacgctc caaaagagct gaagtcgctg
    31861 agtggcggag tttgtcaatc tcatcattaa cagagctgtc cttctcaatg taggtatcac
    31921 tagaagggac ataggcctct ggttggtaat agtcatagta agatacaaag tactcaacag
    31981 cattttcagg gaaaaattcc ttaaactccc cataaagttg tcctgccaga gtcttattgt
    32041 gggcaataac tagagtgggt ttattgactt tggaaatgac ctgactcata gtataggtct
    32101 tccctgttcc agtcgccccc atgagaatct gagctttttc gcccccctcg atattatcta
    32161 ccaactgctc gatagcttga ggttggtctc ctgatggttg atattttgat actagtttaa
    32221 attgattatc tgtaatgcgg ttaatcataa gaatcctctc tccatgtgct actcctattt
    32281 tagcatactt atagtatttt cacgaagaaa aggacggacc gaagtcacat cctttcattt
    32341 tctttcttta atttattagc aagatagaca atcagcagta gtaataccag acttgccata
    32401 atggaacctt ctatgccaaa agaaccacct gatagccaat cttgattgcc ttgtggtaaa
    32461 aaggtcatca gagacgttcc tgacggttga ccactaacta aaatcccaaa gagattaccc
    32521 tgagcaaaat tccaagcacc atgaatacct gcaacacccc aaactgtatc agttttgaga
    32581 aggtaaagag ccatggcaac tccgaataaa aagagattta ctagagatag aggggtgagg
    32641 ccagaattgc ccatatgaag cagggtaaag aacaggctag atataagaat agctagtttt
    32701 agattggttc ttgaggccaa ttgaggaagt agccaagcac gggccaccac ttcttctgct
    32761 gtcccctgta aaatccaaaa tgggatagta aagacgacaa aggcaagaga ataaggattc
    32821 aagtgaatgg attccaaacg atattgacct aagaccacta aacctaacaa ggtcagaaga
    32881 aaaagtgcca ggcctagact aaatcctttc agaagattgc tgaggaaatt ctctctataa
    32941 aatcccaagg ttcgaatagg tcttttctca acttttcttg tccatctgaa cacagtgtta
    33001 agaataaaac caaaggccag taatcctaaa attaaacgaa agtcacttgt tttatccgtc
    33061 aagctctgat gcaaggtctg caagtagctt gcaagatttt gaccagcctc tccaaaattt
    33121 ctagcaagtc cgatgagagc taacaaacta ataccatata aagtataagc cacaaactct
    33181 cctatgaaga caaaaacaaa ggctaacaag gggcttgtgt aaatgtttaa actcattttt
    33241 gaagcttgga agtctttaaa tattcttttg ttcttcatat ccccgtcctc ttttc
//
LOCUS       DAVMAH010000023        33111 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVMAH010000023 DAVMAH010000000
VERSION     DAVMAH010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33111
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.023"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..188
                     /locus_tag="VYO94_000992"
     CDS             <1..188
                     /locus_tag="VYO94_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759646.1"
                     /translation="EELELIQGGADSYGKNPNGRYDWEIEPVLTLPVHGFCPRGTYDL
                     GYIGGGNHLCKGSAARF"
     gene            242..913
                     /locus_tag="VYO94_000993"
     CDS             242..913
                     /locus_tag="VYO94_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1759647.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVIMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(965..1162)
                     /locus_tag="VYO94_000994"
                     /pseudo
     CDS             complement(965..1162)
                     /locus_tag="VYO94_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1155..2063
                     /locus_tag="VYO94_000995"
     CDS             1155..2063
                     /locus_tag="VYO94_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1759648.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            2060..2521
                     /locus_tag="VYO94_000996"
     CDS             2060..2521
                     /locus_tag="VYO94_000996"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV1759649.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            2511..3398
                     /locus_tag="VYO94_000997"
     CDS             2511..3398
                     /locus_tag="VYO94_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1759650.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            3401..5284
                     /gene="cbpE"
                     /locus_tag="VYO94_000998"
                     /gene_synonym="pce"
     CDS             3401..5284
                     /gene="cbpE"
                     /locus_tag="VYO94_000998"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV1759651.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            5364..6494
                     /locus_tag="VYO94_000999"
     CDS             5364..6494
                     /locus_tag="VYO94_000999"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV1759652.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            6504..7766
                     /locus_tag="VYO94_001000"
     CDS             6504..7766
                     /locus_tag="VYO94_001000"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV1759653.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMANHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAIGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            7770..8567
                     /gene="proC"
                     /locus_tag="VYO94_001001"
     CDS             7770..8567
                     /gene="proC"
                     /locus_tag="VYO94_001001"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV1759654.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFYQLLAKAGLLVELGES
                     LIDAATGLAGCGPAFVYLFIEALADAGVQTGLPREIALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEVHAFRGTVMDAVHQAYKRTQELGK"
     gene            8787..9425
                     /locus_tag="VYO94_001002"
     CDS             8787..9425
                     /locus_tag="VYO94_001002"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV1759655.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLELHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMDLAK"
     gene            9422..10312
                     /locus_tag="VYO94_001003"
     CDS             9422..10312
                     /locus_tag="VYO94_001003"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV1759656.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            10352..10669
                     /gene="yabA"
                     /locus_tag="VYO94_001004"
     CDS             10352..10669
                     /gene="yabA"
                     /locus_tag="VYO94_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV1759657.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            10672..11541
                     /gene="rsmI"
                     /locus_tag="VYO94_001005"
     CDS             10672..11541
                     /gene="rsmI"
                     /locus_tag="VYO94_001005"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV1759658.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            11768..12286
                     /locus_tag="VYO94_001006"
     CDS             11768..12286
                     /locus_tag="VYO94_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV1759659.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            12395..13041
                     /locus_tag="VYO94_001007"
                     /pseudo
     CDS             12395..13041
                     /locus_tag="VYO94_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(13030..13834)
                     /locus_tag="VYO94_001008"
     CDS             complement(join(13030..13464,13466..13834))
                     /locus_tag="VYO94_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1759660.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKELANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     CRDMKLFKMSRRNIGQAGKILSDSGYQGLMKIYPQVQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKIENIFAKVKTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
     gene            13829..14083
                     /locus_tag="VYO94_001009"
     CDS             13829..14083
                     /locus_tag="VYO94_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1759661.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            14277..15611
                     /gene="trmFO"
                     /locus_tag="VYO94_001010"
     CDS             14277..15611
                     /gene="trmFO"
                     /locus_tag="VYO94_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV1759662.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGAGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLSSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            15695..16432
                     /locus_tag="VYO94_001011"
     CDS             15695..16432
                     /locus_tag="VYO94_001011"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV1759663.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQPGNIKRVVFGENIGTTVSNNIEEKE"
     gene            16441..16998
                     /gene="frr"
                     /locus_tag="VYO94_001012"
     CDS             16441..16998
                     /gene="frr"
                     /locus_tag="VYO94_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV1759664.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDIGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKREKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            17058..17912
                     /gene="cvfB"
                     /locus_tag="VYO94_001013"
     CDS             17058..17912
                     /gene="cvfB"
                     /locus_tag="VYO94_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV1759665.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            17921..18136
                     /locus_tag="VYO94_001014"
     CDS             17921..18136
                     /locus_tag="VYO94_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV1759666.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            18222..19190
                     /locus_tag="VYO94_001015"
     CDS             18222..19190
                     /locus_tag="VYO94_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV1759667.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            19259..20073
                     /locus_tag="VYO94_001016"
                     /pseudo
     CDS             19259..20073
                     /locus_tag="VYO94_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
     gene            complement(20038..20220)
                     /locus_tag="VYO94_001017"
     CDS             complement(20038..20220)
                     /locus_tag="VYO94_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759668.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     RLVRNLVHFIIDDGTN"
     gene            20256..20756
                     /locus_tag="VYO94_001018"
     CDS             20256..20756
                     /locus_tag="VYO94_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1759669.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            20759..21019
                     /locus_tag="VYO94_001019"
                     /pseudo
     CDS             20759..21019
                     /locus_tag="VYO94_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(21386..22485)
                     /gene="ald"
                     /locus_tag="VYO94_001020"
                     /pseudo
     CDS             complement(21386..22485)
                     /gene="ald"
                     /locus_tag="VYO94_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003072563.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            22662..23231
                     /locus_tag="VYO94_001021"
     CDS             22662..23231
                     /locus_tag="VYO94_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1759670.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            23299..23949
                     /locus_tag="VYO94_001022"
     CDS             23299..23949
                     /locus_tag="VYO94_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV1759671.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDSSTEKEVKKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            23933..26173
                     /locus_tag="VYO94_001023"
     CDS             23933..26173
                     /locus_tag="VYO94_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV1759672.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMGNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            26352..26540
                     /locus_tag="VYO94_001024"
     CDS             26352..26540
                     /locus_tag="VYO94_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759673.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYARYEVINYYSGGY"
     gene            26573..27160
                     /locus_tag="VYO94_001025"
     CDS             26573..27160
                     /locus_tag="VYO94_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759674.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            27164..28348
                     /locus_tag="VYO94_001026"
     CDS             27164..28348
                     /locus_tag="VYO94_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759675.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASPGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQMIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKEFFN
                     RF"
     misc_feature    28512..28643
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            28659..29189
                     /gene="infC"
                     /locus_tag="VYO94_001027"
     CDS             28659..29189
                     /gene="infC"
                     /locus_tag="VYO94_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV1759676.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            29222..29422
                     /gene="rpmI"
                     /locus_tag="VYO94_001028"
     CDS             29222..29422
                     /gene="rpmI"
                     /locus_tag="VYO94_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV1759677.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            29474..29833
                     /gene="rplT"
                     /locus_tag="VYO94_001029"
     CDS             29474..29833
                     /gene="rplT"
                     /locus_tag="VYO94_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV1759678.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            29891..30271
                     /locus_tag="VYO94_001030"
     CDS             29891..30271
                     /locus_tag="VYO94_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1759679.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            30521..31321
                     /locus_tag="VYO94_001031"
     CDS             30521..31321
                     /locus_tag="VYO94_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV1759680.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIDGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPENETVSQRVCEDGPVFRTGTVVL"
     gene            31332..32270
                     /locus_tag="VYO94_001032"
     CDS             31332..32270
                     /locus_tag="VYO94_001032"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV1759681.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            32312..>33111
                     /gene="lytB"
                     /locus_tag="VYO94_001033"
     CDS             32312..>33111
                     /gene="lytB"
                     /locus_tag="VYO94_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV1759682.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGK"
BASE COUNT        10011 a         5967 c         7542 g         9591 t
ORIGIN      
        1 atgaagaatt agagctgata caaggtggag cagattcata tggtaaaaat cctaatggta
       61 ggtacgattg ggaaatagaa ccagtattaa ctctgccggt tcatggattt tgtcccagag
      121 gcacctatga tttaggatat attggaggag gcaatcatct ttgcaaagga agtgctgcga
      181 gattttaagt aaaatttatt agtaatatga agaaacaagt ggagaaagca gagaatttaa
      241 tatgaaaaaa cgggctattc aaattttact agcattgtcc ttaatttttt acaaatcaac
      301 ttggttttgg agagttttca atcacctcgc aaagccctat ctaccagcaa gtcgtgaatt
      361 ttttcagatt ctgcttttga tggagagcgg agttcttttc ttagcggtca tctatctact
      421 ggtttttgca ggaaagaaaa tttttcattt caagtggcag ctgaggtact tcatctacct
      481 tttactgggc tacatcattt catatatgtc tgacttcctc ttttcgtatt tcatatccct
      541 gtcttcaaat cagatttctt tgaatgaaac ggtagaaatg atggggagac aggagttccc
      601 ttatttcttg ctcatcgttt gcttcatcgc ccctattgct gaggaattga tttatcgcgg
      661 tgtgattatg acaacctttt tcaaaaactc gccttggtac ggagatgttt tgctttctgc
      721 tattattttc ggttatattc atatcaattt tgctttaact cctcttgctt ttttcattta
      781 tgctagtgga ggtcttattt tagctctatt gtatcgcatg actaaaaatc tctactatcc
      841 aatactagtt catattctca ttaatatcac tgccttctgg gatgtgtggt tgctcctatt
      901 ttcaggaagt tagcttacta aaataatgtc ggaactttcc ggcattttct tttttcacaa
      961 atagtcaacg tttttctttt cgatattgta gtggtgtgta gccagttatt tttttgaatt
     1021 gattttgaaa ataaggttgg cttgagaaag gcagatagtg aagatagtta agaagaatag
     1081 gatgttcttt tttccttttt ggaaaacttc taaaatatgg tataatgaaa agataaagaa
     1141 gttaggggta gaagatgaac attcaacaat tacgctatgt tgtggctatt gccaatagtg
     1201 gtacttttcg tgaagctgct gaaaagatgt atgttagtca gccgagtctg tctatttctg
     1261 ttcgggattt ggaaaaagag ttgggtttta agattttccg tcggaccagc tcagggactt
     1321 tcttgacccg tcgtgggatg gaattttatg aaaaagcgca agaattggtt aaaggatttg
     1381 atatttttca aaatcagtat gccaatcctg aagaagaaaa agatgaattt tccgttgcta
     1441 gccagcacta tgacttctta ccaccaacta ttacggcctt ttcagagcgc tatcctgact
     1501 ataagaactt ccgtattttt gaatcaacta ctgttcaaat attagatgaa gtggcgcaag
     1561 ggcatagtga gattgggatt atctacctca acaatcaaaa taaaaagggg attatgcaac
     1621 gggttgaaaa gttaggtctg gaggtcatcg aattgattcc tttccatacc catatttatc
     1681 tctgtgaggg tcatccttta gcccagaaag aggaattagt catggaggat ttagcggatt
     1741 taccaacggt tcgtttcact caagagaaag acgagtacct ttattattca gagaactttg
     1801 ttgataccag cgctagctca cagatgttta atgtgacaga ccgtgccacc ttgaatggta
     1861 ttttggagcg gacggacgcc tatgcgacag gttctggatt tttagatagt gacagtgtta
     1921 atggcattac agttattcgt ctcaaggata acctagataa ccgcatggtc tatgttaaac
     1981 gtgaagaagt ggagcttagt caagctggga ctctcttcgt agaagtcatg caagaatatt
     2041 ttgatcaaaa gaggaaatca tgaaaaaaag agcaatagtg gcagtcattg tactgctttt
     2101 gattgggctg gatcagttgg tcaaatccta tatcgtccag cagattccac tgggtgaagt
     2161 gcgctcctgg atccccaatt tcgttagctt gacctacctg caaaatcgag gtgcagcctt
     2221 ttctatctta caagatcagc agttgttatt cgctgtcatt actctggttg tcgtgatagg
     2281 tgccatttgg tatttacata aacacatgga ggactcattc tggatggtct tgggtttgac
     2341 tctaataatc gcgggtggtc ttggaaactt tattgacagg gtcagtcagg gctttgttgt
     2401 ggatatgttc caccttgact ttatcaactt tgcaattttc aatgtggcag atagctatct
     2461 gacggttgga gtgattattt tattgattgc aatgctaaaa gaggaaataa atggaaatta
     2521 aaattgaaac tggtggtctg cgtttggata aggctttgtc agatttgtca gaattatcac
     2581 gtagtctcgc gaatgaacaa attaaatcag gccaggtctt ggtcaatggt caagtcaaga
     2641 aagctaaata cacagtccaa gagggtgatg tcgtcactta ccatgtgcca gaaccagagg
     2701 tattagagta tgtggctgag gatcttccgc tagaaatagt ctaccaagat gaggatgtgg
     2761 ctgtcgttaa caaacctcag ggaatggttg tgcacccgag tgctggtcat accagtggaa
     2821 ccctagtaaa tgccctcatg tatcatatta aggacttgtc gggtatcaat ggggttctgc
     2881 gtccagggat tgttcaccgt attgataagg atacgtcagg tcttctcatg attgctaaaa
     2941 acgatgatgc gcatctagca cttgcccaag aactcaagga taaaaagtct ctccgcaaat
     3001 attgggcgat tgttcatgga aatctaccta atgatcgtgg tgtaattgaa gcgccgattg
     3061 gccggagtga aaaagaccgt aagaaacagg ctgtaactgc taaagggaag cctgcagtga
     3121 cgcgttttca cgtcttggaa cgctttggcg attatagctt agtagagttg caactggaga
     3181 cagggcgcac tcatcaaatc cgtgtccaca tggcttatat cggccatcca gtcgctggtg
     3241 atgaggtcta tggtcctcgc aagactttga aaggacatgg acaatttctt catgccaaga
     3301 ctttaggttt tactcatccg agaacaggta agaccttgga atttaaagca gatatcccag
     3361 agatttttaa ggaaaccttg gagagattga gaaagtaaga atgaaaaaga aattaactag
     3421 tttagcactt gtaggcgctt ttttaggttt gtcatggtat gggaatgttc aggctcaaga
     3481 aagttcagga aataaaatcc actttatcaa tgttcaagaa ggtggcagtg atgcgattat
     3541 tcttgaaagc aatggacatt ttgccatggt ggatacagga gaagattatg atttcccaga
     3601 tggaagtgat tctcgctatc catggagaga aggaattgaa acgtcttata agcatgttct
     3661 aacagaccgt gtctttcgtc gtttgaagga attgggtgtc caaaaacttg attttatttt
     3721 ggtgacccat acccacagtg atcatattgg aaatgttgat gaattactgt ctacctatcc
     3781 agttgaccga gtctatctta agaaatatag tgatagtcgt attactaatt ctgaacgtct
     3841 atgggataat ctgtatggct atgataaggt tttacagact gctgcagaaa aaggtgtttc
     3901 agttattcaa aatatcacac aaggggatgc tcattttcag tttggggaca tggatattca
     3961 gctctataat tatgaaaatg aaactgattc atcgggtgaa ttaaagaaaa tttgggatga
     4021 caattccaat tccttgatta gcgtggtgaa agtcaatggc aagaaaattt accttggggg
     4081 cgatttagat aatgttcatg gagcagaaga caagtatggt cctctcattg gaaaagttga
     4141 tttgatgaag tttaatcatc accatgatac caacaaatca aataccaagg atttcattaa
     4201 aaatttgagt ccgagtttga ttgttcaaac ttcggatagt ctaccttgga aaaatggtgt
     4261 tgatagtgag tatgttaatt ggctcaaaga acgaggaatt gagagaatca acgcagccag
     4321 caaagactat gatgcaacag tttttgatat tcgaaaagac ggttttgtca atatttcaac
     4381 atcctacaag ccgattccaa gttttcaagc tggttggcat aagagtgcat atgggaactg
     4441 gtggtatcaa gcgcctgatt ctacaggaga gtatgctgtc ggttggaatg aaatcgaagg
     4501 tgaatggtat tactttaacc aaacgggtat cttgttacag aatcaatgga aaaaatggaa
     4561 caatcattgg ttctatttga cagactctgg tgcttctgct aaaaattgga agaaaatcgc
     4621 tggaatctgg tattatttta acaaagaaaa ccagatggaa attggttgga ttcaagataa
     4681 agagcagtgg tattatttgg atgttgatgg ttctatgaag acaggatggc ttcaatatat
     4741 ggggcaatgg tattactttg ctccatcagg ggaaatgaaa atgggctggg taaaagataa
     4801 agaaacctgg tactatatgg attctactgg tgtcatgaag acaggtgaga tagaagttgc
     4861 tggtcaacat tattatctgg aagattcagg agctatgaag caaggctggc ataaaaaggc
     4921 aaatgattgg tatttctaca agacagacgg ttcacgagct gtgggttgga tcaaggacaa
     4981 ggataaatgg tacttcttga aagaaaatgg tcaattactt gtgaacggta agacaccaga
     5041 aggttatact gtggattcaa gtggtgcctg gttagtggat gtttcgatcg agaaatctgc
     5101 tacaattaaa actacaagtc attcagaaat aaaagaatcc aaagaagtag tgaaaaagga
     5161 tcttgaaaat aaagaaacga gtcaacatga aagtgttaca aatttttcaa ctagtcaaga
     5221 tttgacatcc tcaacttcac aaagctctga aacgagtgta aacaaatcgg aatcagaaca
     5281 gtagtagaaa agaaggtttt agggccttct ttttcctatc aactcttttc tatttcctgt
     5341 tattcatgtt ataatggata aatatgaata atcggagtga gactatgaaa tacaaacgga
     5401 ttgtctttaa ggtgggtact tcttctctga caaatgagga tggaagttta tcacgtagta
     5461 aggtaaagga tattacccag cagttggcta tgctgcacga ggctggtcat gagttgattt
     5521 tggtgtcttc aggtgccatt gcggctggtt ttggagcctt aggatttaaa aagcgtccga
     5581 ctaaaattgc tgataaacag gcttcagcag cggtagggca gggacttttg ttggaagaat
     5641 atacgaccaa tcttctcttg cgtcaaatcg tttctgcaca aatcttgctg acccaagatg
     5701 actttgtgga taagcgtcgt tataaaaatg cccatcaggc tttgtcggtt ttgctcaacc
     5761 gtggggcaat tcctatcatc aatgagaatg atagtgtcgt tattgatgag ctcaaggttg
     5821 gggacaatga cactctaagt gctcaagtag cggcgatggt ccaagcagac cttttagttt
     5881 tcttgacaga tgtggacggt ctctatactg gaaatcctaa ttcagatcca agagccaaac
     5941 gcttggagag aatcgagacc atcaatcgtg agattattga tatggctggt ggagctggtt
     6001 cgtcaaacgg aactgggggt atgttaacca aaatcaaggc tgcaactatc gcgacggaat
     6061 caggagttcc tgtttatatc tgctcatcct tgaaatcaga ttccatgatt gaggcggcag
     6121 aggagaccga ggatggttct tactttgttg ctcaagagaa ggggcttcgt acccagaaac
     6181 aatggcttgc cttctatgct cagagtcaag gttctatttg ggttgataaa ggggctgcgg
     6241 aagctctctc tcaacatgga aagagtcttc tcttatctgg tatcgttgaa gcagaaggag
     6301 ccttttctta cggtgatatc gtgacagtat ttgacaagga aagtggaaaa tcacttggaa
     6361 aaggacgcgt gcaatttgga gcatctgctt tggaggatat gttgcgttct caaaaagcca
     6421 agggtgtctt gatttaccgt gacgactgga tttccattac tcctgaaatc caactacttt
     6481 ttacagaatt ttagaggtaa actatggtga gtagacaaga acaatttgaa caggtacagg
     6541 ctgttaaaaa atcgattaac acagctagtg aagaagtgaa aaaccaagcc ttgctagcca
     6601 tggctaatca cttagtggct gctactgagg aaattttagc ggctaatgcc ctcgatatgg
     6661 cagcggctaa ggggaaaatc tcagatgtga tgttggatcg tctttatttg gatgcagatc
     6721 gtatagaagc gatggcaaga ggaattcgtg aagtggttgc cttaccagat ccaatcggtg
     6781 aagttttaga aacaagtcag cttgaaaatg gtttggttat cacaaaaaaa cgtgtagcta
     6841 taggtgtcat cggtattatc tatgaaagcc gtccaaatgt gacgtctgat gcggctgctt
     6901 tgactcttaa gagtggaaat gcggttgttc ttcgtagtgg taaggatgcc tatcaaacaa
     6961 cccatgccat tgtcacagcc ttgaagaagg gcttggagac gactactatt catccaaatg
     7021 tgattcaact ggtggaggat actagccgtg aaagtagtta tgctatgatg aaggccaagg
     7081 gctatctaga ccttctcatt cctcgtggag gagctggctt gatcaatgca gtggttgaga
     7141 atgcgattgt acctgttatc gagacaggga ctgggattgt ccatgtctat gtggataagg
     7201 atgcagacga agacaaggcg ctgtctatca tcaacaatgc taaaaccagt cgtccttctg
     7261 tttgtaatgc catggaggtt ctgctggttc atgaaaacaa ggcagcaagc atccttcctc
     7321 gcttggatca aatgctggtt gcagagcgta aggaagctgg actggaacca attcaattcc
     7381 gcttggatag caaagcaagc cagtttgttt caggtcaagc agctgagacc caagactttg
     7441 acaccgagtt tttagactat gtccttgctg ttaaggttgt gagcagttta gaagaagcgg
     7501 ttgcgcacat tgaatcccac agcacccatc attcggatgc tattgtgacg gaaaatgctg
     7561 aagctgcagc atactttaca gatcaagtgg actctgcagc ggtgtatgtt aatgcctcaa
     7621 ctcgtttcac agatggagga caatttggtc ttggttgtga aatggggatt tctactcaga
     7681 aattgcacgc gcgtggtccc atgggcttga aagagttgac cagctacaag tatgtggttg
     7741 ccggtgatgg gcagataagg gagtaagaga tgaagattgg atttatcggt ttggggaata
     7801 tgggtgctag cttggcaaaa tctgtcttgc agactaggac gtcagatgag attctccttg
     7861 ccaatcgtag tcaagctaag gtagatgctt tcattgcaga ctttggtggt caggcttcca
     7921 gcaatgaaga aatgtttgca gaagcagatg tgatttttct aggagttaag cctgctcagt
     7981 tttctgaact gctttctcaa taccagacca tccttgaaaa aagagaaagt cttcttttga
     8041 tttcgatggc agctggattg accttagaaa aactagcaag tcttatccca agtcaacacc
     8101 gaattattcg tatgatgcct aatacccctg cttctatcgg gcaaggagtg attagttatg
     8161 ccttgtctcc taattgcagg gctgaggaca gtgagctctt ttatcagctt ttagccaagg
     8221 ctggtctctt ggttgaacta ggagaaagtt taatcgatgc agcgacaggt cttgcaggtt
     8281 gtggaccagc ctttgtctat ctttttatcg aggccttggc agatgcaggt gttcagacag
     8341 gattaccacg agaaatagca ttgaaaatgg cagcacaaac tgtggtagga gctgggcaat
     8401 tggtccttga aagtcagcaa catcctggag tattgaaaga ccaagtctgt agcccaggcg
     8461 gttcgactat cgctggtgta gcaagcctag aagtgcatgc tttccgagga acagtcatgg
     8521 atgcagttca tcaagcctac aaacgaacac aagaactagg taaataagag gtagttttat
     8581 ctgcctcttt tatggtggtt gatactcttc gaaaatcaaa ttcaaactgc gtcagcttca
     8641 ccttgccgta ctcaagtaca gcctgcggct agcttcctag tttgctcttt gattttcatt
     8701 gagtatgaaa tgagaagaca aaaagattgt cacaaacccc tatttttttg atagaataga
     8761 agtagtaaaa aagaaatgag ttagacatgt caaaaggatt tttagtctct cttgagggac
     8821 cagagggagc aggcaagacc agtgttttag aggctctgct accaatttta gaggaaaaag
     8881 gagtaaaggt gctgacgacc cgtgaacctg gcggagtctt gattggggag aagattcggg
     8941 aagtgatttt ggatccaagt catactcaga tggatgctaa aacagagcta cttctctata
     9001 ttgccagtcg cagacagcat ttggtggaaa aagttcttcc agcccttgaa gctggcaagt
     9061 tggtcatcat ggatcgtttt atcgatagtt ctgttgccta tcagggattt ggtcgtggct
     9121 tagatattga agccattgac tggctcaatc agtttgcgac agatggcctc aaacccgatt
     9181 tgacactcta ttttgacatc gaggtggaag aagggctggc tcgcattgct gcgaatagtg
     9241 accgcgaggt caatcgtctg gacttggaag gtttggaatt gcacaagaaa gtccgtcaag
     9301 gctacctttc tctcctggaa aaagaaggaa atcgcattgt caagattgat gctagtctcc
     9361 ctttggagca agttgtggaa actaccaagg ctgtcttgtt tgacggaatg gacttggcca
     9421 aatgaaacaa gatcaactaa aggcttggca accagctcag tttgaccgtt ttgtccgtat
     9481 cttagaacaa gaccagctca atcacgccta tctcttttca ggtttctttg gaagcttgga
     9541 aatggcgcaa tttttagcta agagcctctt ttgtacggat aaagttggcg tcttaccatg
     9601 tgagaaatgc cgaagttgca agctgattga acaggaagag tttccagatg tcaccttgat
     9661 taagccagtc aatcaggtca tcaagacaga acgcattcgg gaattggtgg gacagttttc
     9721 tcaagcaggg attgaaagcc agcaacaggt ctttattatc gagcaagcgg ataaaatgca
     9781 tcccaacgca gccaattctc tgctcaaggt catcgaagaa ccccagagtg aagtttatat
     9841 tttcttcttg actagcgatg aggaaaagat gttaccgaca atccgaagtc ggactcagat
     9901 cttccacttt aaaaagcaag aagaaaaact tatcttactc ttagaacaaa tgggacttgt
     9961 taagaaaaaa gcgactcttt tagctaagtt tagtcaatcg cgagctgaag cagaaaagtt
    10021 ggctaatcag gcaagttttt ggaccttggt cgatgaaagt gaacgcctgc tgacttggtt
    10081 agtagctaag aaaaaagaaa gttatctaca ggttgccaaa ttagccaact tggcagatga
    10141 taaggaaaaa caggatcagg ttttacggat tcttgaagtt ctctgtgggc aggacctctt
    10201 gcaggtaaga gtaagagtga ttctacaaga tttactagaa gctagaaaaa tgtggcaagc
    10261 taatgtcagc tttcaaaatg ccatggaata tctggtcttg aaagaaatat aaactcaaaa
    10321 atgaatgata aagaaaggaa agggctgttt tatggacaaa aaagaattat ttgacgcgct
    10381 ggatgatttt tcccaacaat tattggtaac cttagccgat gtggaagcca tcaagaaaaa
    10441 tctcaagagc ttggtagaag aaaatacagc tcttcgcttg gaaaatagta agttgcgaga
    10501 acgcttgggt gaggtggaag cagacgctcc cgtcaaggcc aagcatgttc gcgaaagtgt
    10561 ccgtcgtatt taccgtgatg gatttcacgt atgtaatgat ttttatggac aacgtcgaga
    10621 gcaggacgaa gaatgtatgt tctgtgatga gttgttatac agggagtaag catgcaaatt
    10681 caaaaaagtt ttaaggggca gtctccctat ggcaagctgt atctagtggc aacgccgatt
    10741 ggcaatctag atgatatgac ttttcgtgct atccagacct tgaaagaagt ggactggatt
    10801 gctgctgagg atacgcgcaa tacagggctt ttgctcaagc attttgacat ttccaccaag
    10861 cagatcagtt ttcatgagca caatgccaag gaaaaaattc ctgatttgat tggtttcttg
    10921 aaagcagggc aaagtattgc tcaggtctct gatgccggtt tgcctagcat ttcagaccct
    10981 ggtcatgatt tagttaaggc agctattgag gaagaaattg cagttgtgac agttccaggt
    11041 gcctctgcag gaatttctgc cttgattgcc agtggtttag cgccacagcc acatatcttt
    11101 tacggttttt taccgagaaa atcaggtcag cagaagcaat tttttggctt gaaaaaagat
    11161 tatcctgaaa cacagatttt ttatgaatca cctcatcgtg tagcagacac gttggaaaat
    11221 atgttagaag tctacggtga ccgctccgtt gtcttggtca gggaattgac caaaatctat
    11281 gaagaatacc aacgaggtac tatctctgag ttattagaaa gcattgctga aacgccactc
    11341 aagggcgaat gtcttctcat tgttgagggt gccagtcagg gtgtggagga aaaggacgag
    11401 gaagacttgt tcgtagaaat tcaaacccgc atccagcaag gtgtgaagaa aaaccaagct
    11461 atcaaggaag tcgctaagat ttaccagtgg aataaaagtc agctctacgc tgcctaccac
    11521 gactgggaag aaaaacaata aagggagaca ggatgtaata attctgtctg tttctgttta
    11581 acttaattag tgatgataat ataaagatgt atcacttggt atagaagctt tggtattaag
    11641 ttttttatta agcccatacg gaataccgat ggttggagca gcagttatag cgttcttaga
    11701 aggtataaat agaaaaataa ggtcatttta aatcaaagga ttgataaatc agaaagaagg
    11761 tgattttttg cgaacatacg aaaataaaga agaactaaaa gctgagatag agaaaacatt
    11821 tgagaaatat attttagaat ttgataatat tccagaaaat ttaaaagata agagagctga
    11881 tgaagttgac agaactccag cagaaaacct tgcttatcag gttggttgga ccaacttggt
    11941 tcttaaatgg gaagaagatg aaagaaaggg gcttcaagta aaaacaccat cggataaatt
    12001 taaatggaat caacttggtg aattatatca gtggttcaca gatacctacg ctcatttatc
    12061 tctgcaagag ttgaaagcaa aattaaatga aaatattaat tctatctctg caatgattga
    12121 ttcgttgagt gaggaagaat tatttgaacc gcatatgaga aagtgggctg atgaagcgac
    12181 taaaacagcg acttgggaag tgtataagtt tattcatgta aatacggttg caccttttgg
    12241 aactttcaga actaaaatca gaaaatggaa gaagatagta ttataaatta tatttttaac
    12301 tttaaaaaat ttcataaaaa tggttaccaa aggcgataga agaaaaacta tcgtcttttt
    12361 ctttgcaaat ttttaagaag ggaggtgatc ttgcatggac tttgaatatt tttataacag
    12421 agaagcggaa agatttaact tcttaaaagt accggagata ttagttgata gagaagaatt
    12481 tcggggctta tcagcagaag caattatcct ttattccata cttcttaaac agacaggaat
    12541 gtcatttaag aataactgga tagacaagga aggcagagta tttatctatt ttactgtcga
    12601 agaaattatg aaaagaagaa atatctcaaa gccaactgcc ataaaaacat tagatgagct
    12661 tgatgtaaaa aaggaatagg actgatcgaa agagtaaggc ttggacttgg taagccgaac
    12721 atcatttatg ttaaagactt tatgagtata tttcaggtaa aagaaaatga cttacagaag
    12781 tcaaaaaact taacttcaga agtaaaagat tttaacctca gaagtaaaga aaatgaactt
    12841 caagaggtta agaaccttga ctctaactat atagagaata ataagagtaa gtatagtaag
    12901 agagaatata gttttggtga aaacggactt ggaacatttc aaaatgtgtt tttagctgct
    12961 gaagatatat cggatttaca aatcataatg aactcacagc ttgagaatta cattagactt
    13021 cctgcaaaac tagaatccta gttcatgatt gataatgcca gcaatcaaat tcattcgtaa
    13081 tccgaagcgt ttacgatgat ttcgatagat tgttgaaaac attttaaacg tttttacttt
    13141 ggcaaagatg ttctcaatct tgcttctctc cttggatagc gcatggttac aggctttatc
    13201 ttcagctgtt agcggcttga gtttgctgga tttacgtgga gtttgtactt gaggatatat
    13261 cttcatgagc ccttgataac cactgtcaga caagatttta ccagcttgtc cgatatttct
    13321 gcgactcatt ttgaacaact tcatatcacg acaatagttc acagcgatat ccaaagaaac
    13381 aattctccct tgacttgtga caatcgcttg agccttcata gcgtgaaatt tctttttacc
    13441 agaatgattc gctaattctt tttttagggc gattgatttt tacttccgtc gcatcaatca
    13501 ttaccgtgtc ctcagaactg agaggagttc ttgaaatcgt aacaccactt tgaacaagag
    13561 ttacttcaac ccattggctc cgacggatta agttgctttc gtgaatacca aaatcagccg
    13621 caatttgttc ataagttcga tattctcgca catattgaag agtggccata agaaggtctt
    13681 ctaggcttaa tttaggtttt cgtccacctt ttgcgtgttt aagttgataa gctgttttta
    13741 atacagctaa tatctcttca aaagtcgtgc gctgaacacc aacaagacgc ttaaatcgtg
    13801 catcagttag ttgtttactt gcttcatcat tcatagaact actataccat attttgtttc
    13861 gcaggaagtc tattggaaag taagaaatat tgaagctgag gctattagaa gaaattgtga
    13921 gcgtggtgct attttttcag gtaaaataaa atatcacgaa gattcacagt ttaaaggaga
    13981 tcactatgtt gaatgttatg ctgttttaga taatacggtt atagcaagag atagaataac
    14041 agtccctatc gatccgttat gtggaaaaga ttttatagag tagcatataa ttgattctta
    14101 actggaatac tcactatctc tttacatcaa gaaaatgact aaacagggaa gtttgccttc
    14161 ttcccttttt ttgttatact agtagaagaa aaaattagaa agatttgtgg gtgtcaaaca
    14221 gcccagtggg gtgttttaat atggacttag gtcccaccca aagaggtatt agtgtcgtgt
    14281 ctcaatctta tatcaatgtt atcggtgctg gtttggcagg ttctgaagca gcttaccaaa
    14341 tcgcagagcg tggtattcca gttaaactat atgaaatgcg tggtgtcaag tctacacccc
    14401 agcataaaac agacaatttt gctgagttgg tttgttccaa ttctttgcgt ggggatgctt
    14461 tgacaaatgc agttggtctt ctcaaggaag aaatgcgtcg cttgggttct gttatcttgg
    14521 aatctgctga ggctacacgt gttcctgcag gtggtgccct tgcagtggac cgtgatggtt
    14581 tctctcaaat ggtgaccgaa aaagttgcca accacccctt gattgaagtg gttcgtgatg
    14641 aaattacaga attgccgaca gatgttatta cggttatcgc tactggtcct ttgacaagtg
    14701 atgccttggc tgaaaagatt catgctctta atgacggtgc tggtttttat ttctacgatg
    14761 cggcagcgcc tattatcgat gtcaacacta tcgatatgag caaggtctac ctcaaatcac
    14821 gttatgataa gggagaagcg gcctacctca atgcccctat gaccaagcaa gaatttatgg
    14881 atttccatga agctttggtc aatgcagaag aagcaccgct tagttctttt gaaaaagaaa
    14941 agtactttga aggatgtatg cctatcgaag tcatggccaa acgtggcatt aaaactatgc
    15001 tttatggccc tatgaagcca gtcggtcttg agtacccaga cgactataca ggacctcgtg
    15061 atggagaatt taaaacacct tatgcggttg tgcaacttcg tcaggataat gcagctggta
    15121 gcctctacaa tattgttggt ttccagaccc acctcaaatg gggagaacaa aagcgtgtct
    15181 tccaaatgat tccgggtctt gaaaatgcgg agtttgtccg ttatggtgtg atgcatcgca
    15241 attcttacat ggattcacca aatcttcttg agcagactta ccgttctaag aaacaaccaa
    15301 atctcttctt tgctggtcaa atgacgggtg tggaaggcta tgttgagtcg gcggcttcag
    15361 gcttagttgc gggaattaac gcagctcgtc tcttcaagga agaaagcgag gctattttcc
    15421 ccgagacgac agcgattgga agcttagctc attacattac ccatgccgac agcaaacatt
    15481 tccaaccaat gaatgtcaat tttgggatca tcaaggagtt ggaaggcgag cgtatccgtg
    15541 ataagaaggc tcgttatgaa aaaattgcag agcgtgccct tgccgactta gaggaatttt
    15601 tgactgtcta atttttttga aagaattgct catgatacta taaaaatctt agaaattgtg
    15661 ataaaatagg taggatgaaa gaaggagagt gaaaatggcg aatcccaagt ataaacgtat
    15721 tttaatcaag ttatcaggtg aagcccttgc cggtgaacgt ggcgtaggga ttgatatcca
    15781 aacagttcaa acaatcgcaa aagagattca agaagttcat agcttaggta tcgaaattgc
    15841 ccttgttatc ggtggaggaa atctctggcg tggagaacct gcagcagaag caggtatgga
    15901 ccgtgttcag gcagattaca caggaatgct tgggactgtt atgaatgctc ttgtgatggc
    15961 agattcattg caacaagttg gggttgatac acgtgttcaa acagctattg ccatgcaaca
    16021 agtggcagag ccttatgtcc gtggacgtgc ccttcgtcac cttgaaaaag gccgtatcgt
    16081 tatctttggt gctggaattg gttcacctta cttctcgaca gatacaacag cggcccttcg
    16141 tgcagctgaa atcgaagcag atgccatcct catggctaaa aatggtgtcg atggtgttta
    16201 caatgccgat cctaagaaag ataagacagc tgttaagttt gaagaattga cccaccgtga
    16261 cgttatcaat aaaggtcttc gtatcatgga ctcaacagct tcaaccctct caatggacaa
    16321 cgacattgac ttggttgtat tcaacatgaa ccaaccaggc aacatcaaac gtgtcgtatt
    16381 tggtgaaaat atcggaacaa cagtttcaaa taatatcgaa gaaaaggaat aagaaagaat
    16441 atggctaacg caattattga aaaagctaaa gagagaatga cccagtctca ccaatcactt
    16501 gctcgtgaat ttggtggtat ccgtgctggt cgtgccaatg caagcttgct tgaccgtgta
    16561 catgtagaat actatggagt cgaaactcct cttaaccaaa tcgcttcaat tacgattcca
    16621 gaagcgcgtg ttttgttggt aacaccattt gacaagtctt cattgaaaga catcgaacgt
    16681 gccttgaacg cttctgatat tggtatcaca ccggctaatg acggttctgt gattcgcttg
    16741 gttatcccag ctcttacaga agaaactcgt cgtgaccttg ctaaagaagt gaagaaggtc
    16801 ggcgaaaatg ctaaagtggc tgtccgcaat atccgtcgcg atgctatgga cgaagctaag
    16861 aaacgagaaa aagcaaaaga aatcactgaa gacgaattga agactcttga aaaagacatt
    16921 caaaaagtaa cagacgatgc tgttaaacac atcgacgaca tgactgctaa caaagagaaa
    16981 gaacttttgg aagtctaaaa ataaacagaa aaactcagtt ggcattgctg gctgagtttt
    17041 attcgaaaga aggaaatatg aatacaaatc ttgcaagttt tatcgttgga ctgatcatcg
    17101 atgaaaacga ccgtttttac tttgtgcaaa aggatggtca aacctatgct cttgctaagg
    17161 aagaaggcca acatacagta ggggatacgg tcaaaggttt tgcatacacg gatatgaagc
    17221 aaaaactccg cctgacaacc ttagaagtga ctgccactca ggaccaattt ggttggggac
    17281 gtgtcacaga ggttcgtaag gacttgggtg tctttgtgga tacaggcctt cctgacaagg
    17341 aaatcgttgt gtcactcgat attctccctg agctcaagga actctggcct aagaagggcg
    17401 accaactcta catccgtctt gaagtggata agaaagaccg tatctggggc ctcttggctt
    17461 atcaagaaga cttccaacgt cttgctcgtc ctgcctacaa caacatgcag aaccaaaact
    17521 ggccagccat tgtttaccgt ctcaagctgt caggaacttt tgtttaccta ccagaaaata
    17581 atatgcttgg ttttattcat cctagcgagc gttacgcaga gccacgtttg gggcaagtat
    17641 tagatgcgcg cgttattggt ttccgtgaag tggaccgcac tctgaacctc tccctcaaac
    17701 cacgctcctt tgaaatgttg gaaaacgatg ctcagatgat tttgacttat ttggaaagca
    17761 atggcggttt catgacctta aatgacaagt catctccaga cgacatcaag gcaacctttg
    17821 gcatttctaa aggtcagttc aagaaagctt taggtggtct tatgaaggct ggtaaaatca
    17881 agcaggacca gtttgggaca gagttgattt agggaggctt atgagaaaat cattttacac
    17941 ttggctcatg accgagcgca atcctaaaag taacagtccc aaagcaattt tggcagacct
    18001 cgcttttgaa gagtcagcct ttccaaaaca cacagatgat tttgatgagg tcagtcgctt
    18061 tttggaggag catgccagtt tctcttttaa cctaggagat tttgacagca tttggcagga
    18121 atatctagaa cactagcatt tattcattgg gtttgggcta gtaatttctc catccctctg
    18181 ctataataaa aagaaataaa aggattagag aggttcttta tttgaaggaa cattcaatag
    18241 acattcaact gagtcatcca gatgacctgt ttcatctttt tggttccaat gaacgccatc
    18301 ttcgtttgat ggaagaagag cttgatgttg tgattcatgc tcgtacggag attgtccagg
    18361 ttttgggaga agagtctgcc tgtgaggaag cccgtcaagt tattcaggct ttgatggtct
    18421 tggtaaatcg tgggatgacc gttggtacgc cagatgtagt cactgcgatt agcatggtca
    18481 aaaatgatga aattgacaag tttgtcgccc tttacgaaga agaaattatc aaagataata
    18541 ctgggaaacc tatccgtgtc aaaaccctag ggcaaaagct ttatgtggac agtgtcaaac
    18601 agcatgatgt gacctttgga attgggccag caggtacagg gaagaccttc cttgcagtga
    18661 ccttggcagt gactgccctt aaacgtgggc aagtcaagcg aattatccta actcgtccag
    18721 cggtggaagc gggagagagt cttggatttc ttccgggtga tcttaaggag aaggtggatc
    18781 cttaccttcg tcctgtttac gatgccttgt atcaaattct tgggaaagac caaacgactc
    18841 gtctcatgga gcgtgaaatt atcgaaattg cgccccttgc ctatatgcgt ggccggacct
    18901 tggatgatgc ctttgtcatt ctcgatgagg cgcaaaacac gaccatcatg cagatgaaga
    18961 tgttcttgac gcgtttaggt tttcattcta agatgattgt caatggagat attagtcaga
    19021 ttgacctgcc acgtaatgtc aagtccggtt tgattgatgc tcaagagaaa ctcaagaaca
    19081 tccatcagat tgactttgtt catttttcag ccaaggatgt ggttcgccat cctgttgtcg
    19141 ctcagattat ccgagcctat gaatattcta ctgaagttgc acacgactga ttttgaggaa
    19201 gttcgcctgc aaaagaatag acttgttcgg taactgtaaa aagtgttata ctatttttat
    19261 ggaaacagta tacgacaaag cacaaaaact taactcaaaa aacttcaaac tattgattgg
    19321 tgtcaaaaag gaaacctttc aactcatgct agaacacctg aattcagcct atcagattca
    19381 gcaccgaaaa ggtggacgtc cacgtagtct gcccatggaa gaccagctca ttatgaccct
    19441 ccgttacttg cgatattatc ccactcagcg tctgctggcc tttgattttg gcgtcggtgt
    19501 agctacggta aatgccatca tcacttgggt ggaggataca cttcgtgcgt caggtagctt
    19561 tgatttggac catttagaag ccccgagtgc tgctgtggct attgacgtga ccgaaagtcc
    19621 gattcagcgt ccaaacaaaa ccaaagcaaa aattattctg gtaaaaagaa acgacacacc
    19681 ttaaaaactc aaattatgct ggatttgacg acacataaag tctgtcaaat ggccttttct
    19741 gacggacata cgcatgattt tactctcttc aaagaaagta ttggacaaag tttgcctgaa
    19801 acgacgcttg cctttgttga cctaggttat ttaggcatct tgaaatttca tgagaatact
    19861 ttcattcctg ctaaaaattc caaaaatcgc cgcctgagtg aggatgataa gcagttaaat
    19921 aaagagatgt cagcgatacg aattgaaatt gaacatttta acgctaaatt caagaccttc
    19981 caaatcatgt cagtccctta tcgtaaccgc agaaaacgtt tcgagttacg ggcggaatta
    20041 atttgtgcca tcatcaatta tgaagtgaac tagattccga acaagtctaa tatacttttg
    20101 agagaggaaa atccagttgt ataggctaaa ggttttatcc aaaggtctga gacaacgatt
    20161 aggcacgatg gaaagaactt ttatgtggct gatgacgatc agtgcatctt cctgtgtcat
    20221 aatcacaggg cacaagaaag taggaatttg aaaagatgat tgaccaacta tctaagtatt
    20281 acagttgtag gatactaact gaaaaggata ttccaagtat tttatcttta tatgaaagta
    20341 atcctctgta ttttcagcat tgtccaccag agccaaattt tgcaactgta aaagaggaca
    20401 tgctttgtct acctgaaggt aaagctaagg ctgataagtt ttttgttgga ttttggaatg
    20461 gatctgacct tgtggctgtt atggattttg tctatgcata tcctgatgag gagactgttt
    20521 ttattggttt gtttatggtt gatcaagcct atcagagaaa agggattggt agtcatattg
    20581 tgacagaagc actagcttat tttgctaaga actttcgaaa ggcacgtttg gcttatgtta
    20641 agggaaatcc gcaatctcag catttttggg aaaagcaggg ctttaaatca attggatgcg
    20701 aggttaagca agaactctat acggttgtta tcgctgaaca gagcctagaa gattagaaat
    20761 ggcatcaagt aagaactatt tggaatttgt tttggaacaa ttatcaggat tagatgatgt
    20821 gacttaccgt tccatgatgg gggagtatat tctttacttc cgcggcaaga ttattggcgg
    20881 catttatgac gatcgctttt tagttaaacc cgtgcaagca gtcttagata agattgacca
    20941 atcttctttt gagtttccat acaaaggtgc caaagaaatg atttgagtgg aagaacttga
    21001 taataagatg tttctataag acctaatttt agctatgtat aaccaactgc caacgcccaa
    21061 acctaaaaag aaaaagcaag ggtgaacgaa gtaaaaaaga agtctgctaa ggccctgtct
    21121 ttgcacgggt aaaattttat atataaaaag aagctgggac taaagagctc agcttccttt
    21181 ggtttatata attgtcatta caagacgaag tggttgggcg aaactctgtt gactttattc
    21241 aatttagagt ttcttatgca caattgagtc tggaacgaaa gtctccagtt gcaaagtata
    21301 cagtacaata aaccaacgat gtaatagctg atgacacaaa gcacagtggg taggacttgc
    21361 gaagtcaccc ttttcttttc aaaatttata ctaaatcatt gatatcagtg tagtcacgat
    21421 taagtccttg agcaactggt aggttagtca agtaaccttg ataagtagtc acaccttgac
    21481 gcaagccttc atcttcagag attgcttgtg cgaatccttt gccagccaaa gcttcgatat
    21541 aaggaagagt gacattggtt agggcgatgg ttgaagtgcg agcaaccgca ccagggatat
    21601 tggcaacggc atagtggaga acaccgtgtt tttcatagac gggttcatcg tgcgttgtca
    21661 cacggtcagc tgtttcgata acgccacctt ggtcaacagc aacgtcaacg atacagagcc
    21721 tggacgcatt tgtttgacca tctcatctgt caccaattcc ggtgcttttg caccagggat
    21781 gagaatggct ccaatcacca catcagcatc tctcacactt gcttcaatgt tgaatgaatt
    21841 agacataaga gtttgaattt gacttccaaa gacttcttct agaactgaga gacgcttgga
    21901 actaatatct aaaatagtca cttgagcacc aagaccaagg gcgatgcggg cagcatgtgt
    21961 accgacgaca ccaccaccga tgatagttac ttttcctttt ggaacacctg gtacaccacc
    22021 aagtagaaca ccagagccac cagcttgctt agtaaggaag tgagctccga tttgaacagc
    22081 catacgacct gcaacctcac tcataggaac gaggagcggt agttgtcctt gattgtcacg
    22141 aacagtttca gttgtttttg ctgttaacat agcatctgct aattctggag cagcggccat
    22201 gtgcaagtag gtgaagagaa gaagatcgtc gcgcaagtaa ccgtattcag aacttaaaga
    22261 ttcttttact ttcacaacca actctgctgc ccaagcttca ccagcagtag cgacaatctc
    22321 agctccttgc ttttgatagt cagcatcagt aaagccagaa ccgagaccag catttgtttc
    22381 gataaggaca cgatgaccac gactaactaa gctatgaaca cctgcaggtg tgagggcgac
    22441 acggttttcg ttatttttaa tttcttttgg gattccgatt aacattgaga taacctacct
    22501 ttcaattgac ggtcttgttt tggttgtcac attccagttc ataaatcaaa aatgtgacgg
    22561 tttcattgta tatgaaaccg cttcaaaaat caagaaaaac ttgtcatcca aattttttta
    22621 tgctagacta gtgaaaatca agctctaatg gagggaaaag tatggaatca atatttgtga
    22681 aatttgccca gtatccgtct atagaaacgg agcgtttatt gctcagacct gtaactttgg
    22741 atgatgcgga agcaatgttt gactatgcct cggacaaggg taatacacgt tacacttttc
    22801 caaccaatca aagcttggaa gaaaccaaga ataacattgc tcagttctac ttggctaatc
    22861 ccttgggacg ttggggaata gaactaaaaa gcaatggtca gtttattgga accattgact
    22921 tgcacaagat tgattctgtt cttaagaagg cagctattgg ctacattatc aataaaaagt
    22981 attggaatca aggattaacg acagaagcca atcgtgctgt gattgagcta gcttttgaga
    23041 agatagggat gaataagttg actgcccttc acgataaggc taatcccgcg tcaggaaagg
    23101 tcatggagaa atcaggcatg cgtttttccc atgcagaacc atatgcttgt atggaccagc
    23161 atgaaaaagg ccgaatcgtg acaagagttc attatgtctt gaccaaggaa gactattttg
    23221 caaataaata agcagttgaa aagaaatttt tcgactgttt tttcttcctc ttacgaataa
    23281 tctaagagag gagaaaatat ggaagcaatt atcgagaaaa tcaaagagta taaaatcatc
    23341 gtcatctgta ctggtctggg cttgcttgta ggaggatttt tcctgctaaa accagctcca
    23401 caaacacctg tcaaagagac gaatttgcag gctgaagttg cagctgtttc caaggactca
    23461 tcgaccgaaa aggaagtgaa gaaggaagaa aaggaagaac cccttgaaca agatctaatc
    23521 acagtagatg tcaaaggtgc tgtcaaatcg ccagggattt atgacttgcc tgtaggtagt
    23581 cgagtcaatg atgctgttca gaaggctggt ggcttgacag agcaagcaga cagcaagtcg
    23641 ctcaatctag ctcagaaagt tagtgatgag gctctggttt acgttcctac taagggagaa
    23701 gaagcagtta gtcaacagac tggttcgggg acagcttctt caacaagcaa ggaaaagaag
    23761 gtcaatctca acaaggccag tctggaagaa ctcaagcagg tcaagggact gggaggaaaa
    23821 cgagctcagg acattattga ccatcgtgag gcaaatggca agttcaagtc agtagacgag
    23881 ctcaagaagg tctctggcat tggtggcaaa acaatagaaa agcttaaaga ctatgttaca
    23941 gtggattaag aatttctcta ttcccctaat ttacctgagt tttctattac tttggcttta
    24001 ttacgctatt ttctcagcat cttatcttgc tttgttgggc tttgtttttc tgctagtctg
    24061 tctctttatc caatttccgt ggaaatctgc tggtaaagtt ctaataattt gcggaatctt
    24121 tggattttgg tttgtttttc aaaattggca acagagtcaa gcgagtcaaa atctggcgga
    24181 ttctgttgaa agggtacgga ttttgcctga tactattaag gttaatggtg atagtctatc
    24241 ctttcgtggc aagtctaacg gtcgtgcttt ccaagtctat tataaactcc agtccgagga
    24301 ggagaaagaa gcctttcaag ctttaactga cctgcatgag ataggactag aagggaagct
    24361 ttcggagcca gaagggcaga gaaattttgg tggctttaat taccaagcct atctgaagac
    24421 tcagggaatt taccagactc tcaatatcaa aacaatccag tcacttcaaa agattggcag
    24481 ttgggatata ggagaaaact tgtccagttt acgtcgaaag gctgtggttt ggattaagac
    24541 gcactttcca gaccctatgg gcaattacat gacaggactc ttgctgggac atctggacac
    24601 cgactttgag gagatgaatg agctttattc cagtctagga attatccacc tctttgccct
    24661 atctggcatg caggtaggtt ttttcatgaa tggatttaag aaacttctct tgcgattggg
    24721 cttgacccaa gaaaagttga aatggctgac ttatcccttt tcccttatct atgcgggact
    24781 aactggattt tcagcatcgg ttattcgcag tctcttgcaa aagctactgg ctcaacatgg
    24841 ggttaagggc ttggataatt ttgccttgac ggtgcttgtc ctctttattg tcatgccaaa
    24901 ctttttcttg acagcaggag gagtcttgtc ctgcgcttat gcttttatcc tgaccatgac
    24961 cagcaaagaa ggggaggggc tcaaggctgt tactagtgaa agtctagtca tctccttggg
    25021 catattgccc attctatcct tctattttgc ggaatttcaa ccttggtcta tccttttgac
    25081 ctttgtcttt tcctttcttt ttgacttggt ctttttaccg ctcttgtcta tcttatttgt
    25141 cctttccttt ctctatccag tcattcagct gaactttatc tttgaatggt tagagggcat
    25201 tattcgcttg gtctcgcagg tggcaaggag accacttgtc tttggtcaac ccaacgcatg
    25261 gcttttaatc ttattgttaa tttccttggc tttggtctat gatttgagga aaaacattaa
    25321 aggattaaca gtattgagtt tattgattac aggtctcttt ttccttacca agtatccact
    25381 ggaaaatgaa atcaccatgc tggatgtggg gcaaggagaa agtattttcc tacgggatgt
    25441 gactgggaaa accattctca tagatgtagg tggtaaggca gaatcttata agaaaatcaa
    25501 aaaatggcaa gaaaagatga cgaccagcaa tgcccagcga accttgattc cctatctcaa
    25561 aagtcgagga gtagctaaga ttgaccagct aattttgact aacacggaca aggagcatgt
    25621 tggagatttg tcagagatga ccaaggcttt ccatgtaggg gagattctag tatcaaaaga
    25681 cagtctgaaa cagaaggaat ttgtggcaga actacaggcg actcaaacaa aggtgcgtag
    25741 tatgatagta ggggagaact tgcccatttt tggaagtcag ttagaagttc tatctccaag
    25801 gaaaatggga gatggaggac acgatgatac cctagttctg tatgggaaat tcttggataa
    25861 gcaatttctc ttcacgggaa atttggagga gaaaggagag aaggacttgc tgaagcacta
    25921 tccagacttg aaagtaaatg ttttgaaagc tagccaacat ggcaataaaa aatcatcaag
    25981 tccagccttt ctagaaaaac tcaaaccaga gcttactctt atctcagttg gaaagagcaa
    26041 tcgaatgaaa ctcccccatc aggaaacatt gacacgactg gaaggtatca atagcaaagt
    26101 ttatcgaact gaccagcaag gagctatacg ttttaagggg ttggatagtt ggaaaatcga
    26161 aagtgttcga taggaaggat aaatgttgta gattagtgaa ataaactaaa aatttgttgc
    26221 ataataatga taaaaatggt ataatgaaaa cgtattcaat attgaggata taaaatcatt
    26281 aaaaatcagc aaaagttgtt ttattagtta gtttataatc tattggtctt cttcagtcca
    26341 gtgtatctgc tgtgacagtc actaaaagtt acaagtatga ttggaatacg gtttgggaat
    26401 atagtaccaa ctatcacgac catcagtatg cttggattcc gtcatggtct cgttatgaca
    26461 gctattctga gtataaagtt ggcggaggct ggaactacgc tcgttatgag gtcataaact
    26521 attacagcgg aggctattaa ttcttaaaga gtgagaaaaa ggagggctag atatgttgca
    26581 gcttactcat gtgaccttaa aaacgcgaca agtcatcttg caagatgtgg atttcacctt
    26641 taaaaagggt agggtttatg gtcttcttgc tatcaatggc tctggaaaga cgaccctgtt
    26701 ccgtgccatt agcaatttaa ttcccataag tagtggaaat atcgcagccc ctccttcttt
    26761 attttattat gagagtattg aatggctgga tggaaactta agtgggatgg actaccttcg
    26821 tcttatcaaa aacatctgga agtcaggtct gaacttgagg gatgaaatcg cctattggga
    26881 aatgtctgac tatatcagtc ttcccattcg caagtattcc ttaggcatga agcaacgctt
    26941 ggtgattgcc atgtatttcc tcagtcaggc caaatgctgg ctcatggatg agattacaaa
    27001 tggcttagat gagtattatc gacagaagtt ttttgatagg ctagcacaaa tcgatagaca
    27061 agaacagctg gttcttttaa gttcccacta taaggaagag ttggttgatg tctgcgatag
    27121 agtagtaacc attcatcagg ggcagataga agaggtttag tttatgaaag atgttagtct
    27181 atttttattg aaaaaagttt tcaaaagccg cttaaactgg attgtcttag ctttatttgt
    27241 atctgtactc ggtgttacct tttatttaaa tagtcagact gcaaactcac acagcttgga
    27301 gagcaggttg gaaagtcgca ttgcagccaa cgagagggct atcaatgaaa atgaagagaa
    27361 actctcccaa atgtctgata ccagctcgga ggaataccag tttgctaaaa ataatttaga
    27421 cgtgcaaaaa aatcttttga cgcgaaagac agaaattctg actttattaa aagaagggcg
    27481 ctggaaagaa gcctactatt tgcagtggca agatgaagag aagaattatg aatttgtatc
    27541 aaatgacccg actgctagcc ctggcttaaa aatgggggtt gaccgcgaac ggaagattta
    27601 ccaagccctg tatcccttga acataaaagc acatactttg gagtttccga cccacgggat
    27661 tgatcagatt gtctggattt tagaggttat catcccaagt ttgtttgtgg ttgctattat
    27721 ttttatgcta acacaactat ttgcagaaag atatcaaaat catctggaca cagctcactt
    27781 atatcctgtt tcaaaagtga catttgcaat atcctctctt ggagttggag tgggatatgt
    27841 aactgtgctg tttatcggaa tctgtggctt ttcttttcta gtgggaagtc tgataagtgg
    27901 ttttggacag ttagattatc cctacccaat ttatagctta gtgaatcaag aagtaactat
    27961 tgggaaaata caagatgtat tatttcctgg cttgctctta gctttcttag cctttatcgt
    28021 cattgtggaa gttgtgtact tgattgctta ctttttcaag caaaaaatgc ctgtcctctt
    28081 tctttcactc attgggattg ttggcttatt gtttggtatc caaaccattc agcctcttca
    28141 aatgattgca catctgattc cctttactta cttgcgttca gtggagattt tatctggaag
    28201 attacctaag cagattgata atgtcgatct aaattggagc atgggaatgg tcttacttcc
    28261 ttgcctgatt atctttttgc tattgggaat tctatttatt gaaagatggg gaagttcaca
    28321 gaaaaaagaa ttttttaata gattctagct ttcctatagg tagggaaaat aagtaaaaac
    28381 taacatagag agggaatcaa cttgattctc tctttttgat tcgaaaacca aaccaaaata
    28441 caaacacaaa cttttcaaaa aataactttt tatcttgaca agagctagaa aacttggtat
    28501 catataaaag ttgagaaaag cagaagtgag agcttctcgc cttgtgacat taagttgcct
    28561 ggccctacgg atgaaaagtt tcgaagaaac gctatcataa cgtgcgggct tgtatattta
    28621 caagtccgct attgtttttc tctaataaaa caaaagaggt gaaaaccata gcaaagcaag
    28681 acttattcat caatgatgag attcgtgtac gtgaagttcg cttgattggt cttgaaggag
    28741 aacagctagg tatcaagcca ctcagtgaag cgcaagcttt ggctgataac gctaatgttg
    28801 acctagtatt gattcaaccc caagccaaac cgcctgttgc aaaaattatg gactacggta
    28861 agttcaaatt tgagtaccag aagaagcaaa aagaacaacg taaaaaacaa agcgttgtta
    28921 ctgtgaaaga agttcgtcta agtccaacaa ttgacaaggg tgactttgat acaaaacttc
    28981 gtaatgcacg taagttcctt gaaaaaggaa ataaagttaa ggtatctatt cgctttaagg
    29041 gtcgtatgat tacccataaa gagattggtg caaaagtttt agccgagttt gctgaagcaa
    29101 ctcaagatat tgccatcatc gaacaacgtg ctaaaatgga tggacgtcaa atgttcatgc
    29161 aattggcgcc agcgactgac aaaaaataat tgtcagaaag ttaaataaag gagaaaaaat
    29221 catgccaaaa caaaaaacac accgcgcatc agctaaacgt ttcaaacgta caggttctgg
    29281 tggacttaaa cgtttccgtg cttacacttc tcaccgtttc cacggaaaaa ctaagaaaca
    29341 acgtcgtcat cttcgtaaag catctatggt gcattcagga gattacaaac gtatcaaagc
    29401 aatgcttact cgcttgaaat aatagcttga ctgtaagtaa acaattctag gaaatatttg
    29461 gaggaaataa aacatggcac gtgttaaagg tggcgttgta tcacgcaaac gtcgtaaacg
    29521 tattcttaaa ttagcaaaag gttactatgg agctaaacac atcttgttcc gtactgcaaa
    29581 agaacaagta atgaactctt actactatgc ataccgtgac cgtcgtcaga aaaaacgtga
    29641 cttccgcaaa ttgtggatta ctcgtatcaa tgcggcagct cgtatgaacg gactttcata
    29701 ctcacaattg atgcatggtt tgaaattggc tgagatcgaa gttaaccgta aaatgcttgc
    29761 tgacttggct gttaacgatg cagtagcttt cacagctctt gcagatgcag ctaaagcaaa
    29821 acttggtaaa taacaactga tgagactgga acaggattgt ccagtctttt taaaaataaa
    29881 ggagaaagat atggcttcaa aaatgctaca cacttgctta cgagtagaaa atcttgaaaa
    29941 atcaatcgca ttttatcaag atgcttttgg ttttaaagaa ttgcgtcgca gagattttcc
    30001 agaccatgcc ttcacgattg tctatctagg tcttgagggc gatgactatg agttggagtt
    30061 gacttataac tacgatcacg gtccgtatgt ggttggtgat gggtttgccc atatcgccct
    30121 cagtacacct gatcttgagg cacttcatca agaacacagt gcaaaaggct atgaagtgac
    30181 tgagccaaat ggtctaccag gaactacacc aaactattac tttgtcaaag accctgatgg
    30241 atataaggtc gaagtcattc gtgaaaaata atttcgtgca agttaagtag aatattcgtt
    30301 ttctacttga ctttttttag ctgaaagagt atactaataa aaattcaacc tttaagggga
    30361 gtccagagag actcacaagg tgtcagataa aagaatggtg caattttcta gaggagactt
    30421 tttgagtgtg ctctcttgtg ttgtacgatt ttaactgagg ccttgcacta gcaaggtctt
    30481 ttctttatct ggtcccctta aaatttaagg aggaaaagtt atgaatccca catgtaagaa
    30541 gcgtttgggt gtcattcggt tggaaaccat gaaggtggtt gcacaagagg aaatcgcgcc
    30601 agcaatcttt gaattagtcc tagaaggaga aatggttgaa gccatgcgag caggccaatt
    30661 tcttcatctg cgtgtaccgg acgatgccca tctcttacgt cgtcctattt caatttcgtc
    30721 tattgacaag gcaaacaagc agtgtcacct catttatcgg attgacggag ctgggactgc
    30781 aattttttca accttaagtc agggagacac tcttgatgtg atggggcctc agggaaatgg
    30841 ttttgacttg tctgaccttg atgagcagaa tcaggttctc cttgttggtg gtgggattgg
    30901 tgttccaccc ttgcttgagg tggccaagga attgcatgaa cgtggagtga aagtagtgac
    30961 agtcctcggt tttgctaata aggatgctgt tattttgaaa acggaattgg ctcagtatgg
    31021 tcaggtcttt gtaacgacag atgatggttc ttatggcatc aagggaaatg tttccgttgt
    31081 tatcaatgat ttagacagtc agtttgatgc tgtttactcg tgtggggctc caggaatgat
    31141 gaagtatatc aatcaaacct ttgatgatca cccaagagcc tatttatctc tggaatctcg
    31201 tatggcttgt gggatgggag cttgctatgc ctgtgttcta aaagtaccag aaaacgagac
    31261 ggtcagccaa cgcgtctgtg aagatggtcc tgttttccgc acaggaacag ttgtattata
    31321 aggagaaaat tatgactaca aatcgattac aagtttctct acctggtttg gatttgaaaa
    31381 atccgattat tccagcatca ggctgttttg gctttggaca agagtatgcc aagtactatg
    31441 atttagacct tttaggttct attatgatca aggcgacaac ccttgaacca cgttttggga
    31501 atccaactcc aagagtggca gagacgcctg ctggtatgct caatgcaatt ggcttgcaaa
    31561 atcctggttt agaggttgtt ttggctgaaa agctaccttg gctggaaaga gaatatccaa
    31621 atcttcctat tattgccaat gtagctggtt tttcaaaaca agagtatgca gctgtttctc
    31681 atgggatttc caaggcaact aatgtaaaag ctatcgagct caatatttct tgtcccaatg
    31741 ttgaccactg taatcatgga cttttgattg gtcaagatcc agatttggct tatgatgtgg
    31801 tgaaagcagc tgtggaagcc tcagaagtgc cagtttatgt caaattaacc ccgagtgtga
    31861 ccgatatcgt tactgtcgca aaagctgcag aagatgcggg agcaagtggc ttgaccatga
    31921 tcaatactct ggttggaatg cgctttgacc tcaaaactag aaaaccaatc ttggccaatg
    31981 gaacaggtgg aatgtctggt ccagcagtct ttccagtagc cctcaaactc atccgccaag
    32041 ttgcccaaac aacagacctg cctatcattg gaatgggagg agtggattcg gctgaagctg
    32101 ccctagaaat gtatctggct ggggcatctg ctatcggagt tggaacagct aactttacca
    32161 atccttatgc ctgccctgac atcatcgaaa atttaccaaa agtcatggat aaatacggta
    32221 ttagcagtct ggaagaactc cgtcaggaag taaaagagtc tctgaggtaa actgcaatca
    32281 atctgttctt gattttttat tagtttgtaa tatgaattta ggagaatttt ggtacaataa
    32341 aataaataag aacagaggaa gaaggttaat gaagaaagta agatttattt ttttagctct
    32401 gctatttttc ttagctagtc cagagggtgc aatggctagt gatggtactt ggcaaggaaa
    32461 acagtatctg aaagaagatg gcagtcaagc agcaaatgag tgggtttttg atactcatta
    32521 tcaatcttgg ttctatataa aagcagatgc taactatgct gaaaatgaat ggctaaagca
    32581 aggtgacgac tatttttacc tcaaatctgg tggctatatg gccaaatcag aatgggtaga
    32641 agacaaggga gccttttatt atcttgacca agatggaaag atgaaaagaa atgcttgggt
    32701 aggaacttcc tatgttggtg caacaggtgc caaagtaata gaagactggg tctatgattc
    32761 tcaatacgat gcttggtttt atatcaaagc agatggacag cacgcagaga aagaatggct
    32821 ccaaattaaa gggaaggact attatttcaa atccggtggt tatctactga caagtcagtg
    32881 gattaatcaa gcttatgtga atgctagtgg tgccaaagta cagcaaggtt ggctttttga
    32941 caaacaatac caatcttggt tttacatcaa agaaaatgga aactatgctg ataaagaatg
    33001 gattttcgag aatggtcact attattatct aaaatccggt ggctacatgg cagccaatga
    33061 atggatttgg gataaggaat cttggtttta tctcaaattt gatgggaaaa t
//
LOCUS       DAVMAH010000024        31869 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVMAH010000024 DAVMAH010000000
VERSION     DAVMAH010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31869
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.024"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            361..1524
                     /locus_tag="VYO94_001034"
     CDS             361..1524
                     /locus_tag="VYO94_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV1759683.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1521..2198
                     /locus_tag="VYO94_001035"
     CDS             1521..2198
                     /locus_tag="VYO94_001035"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV1759684.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2188..3042
                     /locus_tag="VYO94_001036"
     CDS             2188..3042
                     /locus_tag="VYO94_001036"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV1759685.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3061..4128
                     /locus_tag="VYO94_001037"
     CDS             3061..4128
                     /locus_tag="VYO94_001037"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV1759686.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4138..5304
                     /gene="aroC"
                     /locus_tag="VYO94_001038"
     CDS             4138..5304
                     /gene="aroC"
                     /locus_tag="VYO94_001038"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV1759687.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5314..6417
                     /locus_tag="VYO94_001039"
     CDS             5314..6417
                     /locus_tag="VYO94_001039"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV1759688.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            6428..6766
                     /locus_tag="VYO94_001040"
     CDS             6428..6766
                     /locus_tag="VYO94_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV1759689.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6858..8141
                     /gene="aroA"
                     /locus_tag="VYO94_001041"
     CDS             6858..8141
                     /gene="aroA"
                     /locus_tag="VYO94_001041"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV1759690.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8134..8610
                     /locus_tag="VYO94_001042"
     CDS             8134..8610
                     /locus_tag="VYO94_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV1759691.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8607..9455
                     /gene="pheA"
                     /locus_tag="VYO94_001043"
     CDS             8607..9455
                     /gene="pheA"
                     /locus_tag="VYO94_001043"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1759692.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYTEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9452..10726
                     /gene="psr"
                     /locus_tag="VYO94_001044"
     CDS             9452..10726
                     /gene="psr"
                     /locus_tag="VYO94_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV1759693.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11005..11850
                     /locus_tag="VYO94_001045"
     CDS             11005..11850
                     /locus_tag="VYO94_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1759694.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPDERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSCILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11840..12943
                     /locus_tag="VYO94_001046"
     CDS             11840..12943
                     /locus_tag="VYO94_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1759695.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEEFLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            12945..13931
                     /locus_tag="VYO94_001047"
     CDS             12945..13931
                     /locus_tag="VYO94_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1759696.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            13947..15380
                     /locus_tag="VYO94_001048"
     CDS             13947..15380
                     /locus_tag="VYO94_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV1759697.1"
                     /translation="MIDGKRLLFSLTIVSYTLTIVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15409..16443
                     /locus_tag="VYO94_001049"
     CDS             15409..16443
                     /locus_tag="VYO94_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1759698.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16643..17380
                     /gene="mecA"
                     /locus_tag="VYO94_001050"
     CDS             16643..17380
                     /gene="mecA"
                     /locus_tag="VYO94_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV1759699.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17531..18817
                     /locus_tag="VYO94_001051"
     CDS             17531..18817
                     /locus_tag="VYO94_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV1759700.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQEFGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18819..19688
                     /locus_tag="VYO94_001052"
     CDS             18819..19688
                     /locus_tag="VYO94_001052"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV1759701.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            19901..20839
                     /gene="msrB"
                     /locus_tag="VYO94_001053"
     CDS             19901..20839
                     /gene="msrB"
                     /locus_tag="VYO94_001053"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1759702.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            20897..22621
                     /locus_tag="VYO94_001054"
     CDS             20897..22621
                     /locus_tag="VYO94_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759703.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VLVAILTIVIVGLSRLVNPFYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            22623..24374
                     /locus_tag="VYO94_001055"
     CDS             22623..24374
                     /locus_tag="VYO94_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759704.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGILDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            24721..25980
                     /locus_tag="VYO94_001056"
     CDS             24721..25980
                     /locus_tag="VYO94_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV1759705.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    26056..26191
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            26230..26730
                     /locus_tag="VYO94_001057"
     CDS             26230..26730
                     /locus_tag="VYO94_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV1759706.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            26806..27174
                     /gene="rplL"
                     /locus_tag="VYO94_001058"
     CDS             26806..27174
                     /gene="rplL"
                     /locus_tag="VYO94_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV1759707.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            27361..27531
                     /locus_tag="VYO94_001059"
     CDS             27361..27531
                     /locus_tag="VYO94_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759708.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            27531..27779
                     /locus_tag="VYO94_001060"
                     /pseudo
     CDS             27531..27779
                     /locus_tag="VYO94_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            27793..28116
                     /locus_tag="VYO94_001061"
     CDS             27793..28116
                     /locus_tag="VYO94_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759709.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLW
                     EVSHD"
     gene            28109..28489
                     /locus_tag="VYO94_001062"
     CDS             28109..28489
                     /locus_tag="VYO94_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1759710.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLVVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLYN"
     gene            28502..28645
                     /locus_tag="VYO94_001063"
     CDS             28502..28645
                     /locus_tag="VYO94_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759711.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            28738..29325
                     /locus_tag="VYO94_001064"
     CDS             28738..29325
                     /locus_tag="VYO94_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1759712.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRNLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            29527..29664
                     /locus_tag="VYO94_001065"
                     /pseudo
     CDS             29527..29664
                     /locus_tag="VYO94_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
     gene            29954..31357
                     /locus_tag="VYO94_001066"
     CDS             29954..31357
                     /locus_tag="VYO94_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEV1759713.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            31546..>31869
                     /locus_tag="VYO94_001067"
     CDS             31546..>31869
                     /locus_tag="VYO94_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759714.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVL
                     KKVNLY"
BASE COUNT         9618 a         5713 c         7072 g         9466 t
ORIGIN      
        1 ttgtaacaaa aggcttctct ataaaatcaa attttccaga tacctattga agcagattta
       61 tttcttcatc tttcttctac tacctttgtc actaaatttg acagacacat attgctgatt
      121 caacctctct acctataatc tcacagttaa cctgaggcta gtttcatagt ttgttatttg
      181 attttcgttg ataaaaagaa atgctcctcc aagacggaag agcatttttt attgtgattc
      241 ttacacattt acttcctagt tttgcaggaa gtctagtata ccatttttta aaagaagagt
      301 aaaaaagcaa gggtagtttc ttttttgaga attgtctaaa agtttgatat aatggtggtt
      361 atgaatagaa taagagtcag caaaagggtt gaaaagaagc ttgctaaggg gctagtttta
      421 ctagaagcca gtgatcttga gaatgtcaat cttaaggatc aggaagtaga ggtgcagggt
      481 caggaaggaa actttcttgg gactgcctac ctttctcagc aaaacaaggg cttgggctgg
      541 tttgtcagca aagacaaggt ggccttcaat caaactttct ttgaaacgtt gtttagaaaa
      601 gccaaagaaa agagaaacgc ctactatcaa gatgatttga caactgcctt tcgtctcttt
      661 aatcaagagg gagatggctt tgggggtctg acagtggacc tttatggcga ctacgccgtc
      721 ttttcttggt ataactctta tgtttatcag attcgtcaga ctatatcaga agcctttaga
      781 caggttttcc ctgaggtttt aggggcttat gagaaaatcc gctttaaggg ttttgactat
      841 gaatctgccc atgtttatgg tcaagaagca cctgactttt tcactgtttt agaaaatggt
      901 gtcctgtatc aagtctttat gaatgatggc ttgatgacag gaattttcct agaccagcat
      961 gaggttcgcg gtagtttagt tgacggcttg gctatgggta aatccttgct caatatgttt
     1021 tcctacacag cggctttttc agtagctgcg gccatgggag gagctagcca gacaacttct
     1081 gttgatctag ccaaacgttc acgagaattg tctcaagcgc attttcaggc aaatgggctc
     1141 agcacagacg agcatcgttt tatagtcatg gatgtctttg agtatttcaa atatgccaaa
     1201 cgcaaagact tgacctacga tgttattgtc ctagatccgc ctagctttgc tcggaataaa
     1261 aaacaaactt tctctgtggc caaggattat cacaagttga tttcccagag tcttgagatt
     1321 ttaaatccgg gagggattat cattgccagt accaatgctg ccaatgtttc ccgtcagaaa
     1381 tttacagaac aaattgataa aggttttgca ggaagaagtt accagatttt aaacaaatat
     1441 ggtcttccag cagattttgc ctataataaa aaagatgaaa gtagtaatta cctcaaggtg
     1501 attagtatga aggttagtaa atgaaattaa tcgtttcagt aatgccaaga agtttagagg
     1561 aggctcaggc tctggatgcc acgaggtacc tggatgccga catcattgaa tggcgtgccg
     1621 actatctgcc taaagaagcg attttgcagg tagctccagc catttttgaa aaattcgcag
     1681 gccgtgagtt ggttttcacg ctacgaactc gctccgaagg tggagaaatc gacctttctc
     1741 cagaagagta tatccatcta atcaaggaag ttgcgcaatt ctatcaacca gactatattg
     1801 attttgagta ctatagctac aaggatgttt ttgaggaaat gctggacttc ccaaatcttg
     1861 ttttgagtta ccataatttc caagaaacac ctgagaacat gatggaaatc ttgtcagagt
     1921 tgacgatcct aaatccaaaa cttgttaagg ttgcggtgat ggctcacacg gagcaggatg
     1981 tcttagactt gatgaactat acacgaggct ttaaaaccct caatcctgaa caggaatatg
     2041 tgaccatttc tatgggtaag gtgggcaagg tctctcgtat cactgcggat gtgactggtt
     2101 cgagttggtc ttttgccagt ctggatgagg ttagtgcccc tgggcagatt tctctagcta
     2161 gcatgaaaaa aatcagggag attttggatg aagcttgatg gctatacacg tttagctgca
     2221 gttgttgcca atcctattaa gcattctatt tctcccttca tccacaatag agcctttgag
     2281 gcgacagcta ccaacggtgc ttatgtggct tgggagattg aagcgagtga cttggtagaa
     2341 acagtggcca atattcgtcg ctaccagatg tttggcatca atctgtccat gccctataag
     2401 gagcaggtga ttccttattt ggataagctg agcgatgaag cgcgcttgat tggtgcggtt
     2461 aatacggttg tcaatgagaa tggcaattta attggatata atacagatgg caagggattt
     2521 tttaagtgct tgccttcttt tacaatttca ggtaaaaaga tgaccctgct gggtgcaggt
     2581 ggtgcggcta aatcaatctt ggcacaggct attttggatg gcgtcagtca gatttcggtc
     2641 tttgttcgtt ccgtttctat ggaaaaaaca agaccttacc tagacaagtt acaggagcag
     2701 acaggcttta aagtggattt gtgtgcttta gaatatgttt ctgaactgca agcaaggatt
     2761 gccgagtcgg atttgctagt taatgccacc agtgtgggca tggatggcca atcctctcct
     2821 gttcctgaaa acatagtctt accagaaact cttttagttg cagatatcat ataccaaccc
     2881 tttgaaacac cgtttttgaa atgggctaga agtcagggca atccagcagt caatggtctg
     2941 ggaatgttgc tctatcaagc tgcagaagct tttcaactgt ggacaggcaa ggaaatgccg
     3001 acagaagaga tttggcagtc tttaacagaa aaataccaat aaagaaaggg agactctcct
     3061 atgaaaatca gaatcgatat tcctcatcat ccttatgata ttcagattga aaaaggttgt
     3121 atggcccagg ctggtcagtg gttgcgagaa ctctggcaac cgcaaaaggt agtcattgtg
     3181 acagataacc atgtagcctc tctctatgca gagaaggtca agctcagcct agaagatgct
     3241 ggttttcagg tagctgtttt tgatttctta gaaggtgaag aaagaaagaa tttaactact
     3301 gttcagaaag tctatgaatt tctagtcaag caaggtctga ctcgtagcga tggaatcgtt
     3361 gctcttggtg gtggcgttgt tggggacctg gctggctttg tagcctctac ctatatgcgg
     3421 ggtattcact ttgttcagat tccgactagt ttgacagctc aggttgattc ttctatcggt
     3481 ggaaagacag gcgttaacac accatttgct aaaaatatgg tggggacctt tgcccaacca
     3541 gatggggttc tgattgatcc acttgttctt gaaaccctcg gaaaaagaga gttgattgaa
     3601 gggatgggtg aagttatcaa gtatggcttg attgaggatc cagaactgtg ggctctcttg
     3661 acgggactga atggttctgt tgagagtatt ttggaacatg cagagacctt gattgaacat
     3721 tcttgtcagg tgaagcgcaa gatggtggtt gaagatgagt tggacaatgg tattcgtctt
     3781 tacctcaatt ttggccacac tattggccat gccatcgaag cgactgccgg ttatggcaag
     3841 gtcatgcatg gagaggctgt tgccatggga atggtacaga tttccaagat tgctgaggaa
     3901 aaaggcctca tgccagctgg cattacccaa tctatcacag agatgtgtca gaaattcggc
     3961 ttgcctgttg actatgaaaa ttggaaagtt gacaagcttt atcaggctct tactcatgac
     4021 aagaaagcgc gtggtaacac cttgaaattg gtcttggtgc cagagcttgg ttcagcgacc
     4081 attcacccag tttctctgga agagatgaaa gactacttgg taaaataagg agagtgtatg
     4141 agatatttaa ctgcaggaga atcacacggc ccccgtctaa cagctattat tgagggaatt
     4201 ccagctggac ttccattgac agctgaggat atcaatgagg atcttagacg ccgtcagggt
     4261 ggctacggtc gtggtggtcg tatgaagatt gagagtgacc aggttgtctt tacttcgggt
     4321 gttcgccacg ggaagacgac aggggcgcct attactatgg atgtcatcaa taaggaccac
     4381 cagaaatggc tggacatcat gtctgcggag gacattgaag accgccttaa aagcaagcgg
     4441 aaaattactc atcctcgccc aggtcatgcc gatttggttg gggggattaa gtaccgtttt
     4501 gatgatttgc gaaattcttt ggagcgttca tcagctcgtg aaaccaccat gcgggtggca
     4561 gttggtgcag tagccaaacg cctcttggct gagctggata tggagattgc caaccatgtc
     4621 gtggtctttg gtggtaagga aatagatgtt cctgaaaatc tgacagtcgc tgaaattaag
     4681 caaagagctg cccagtctga agtttctatt gtcaaccaag aacgagaaca ggaaatcaag
     4741 gactatattg accaaatcaa acgtgatggt gataccatcg gtggggttgt ggagacagtc
     4801 gtcggaggcg ttccagttgg tcttggttcc tatgtccaat gggatagaaa attggatgca
     4861 agattggctc aagctgttgt ctctatcaat gcctttaaag gggtggaatt tggtcttggc
     4921 tttgaggctg gttatcgtaa aggcagccaa gttatggatg aaattctctg gtctaaagaa
     4981 gacggttata ctcgccgtac caataatcta ggtggttttg aaggtggtat gactaatggg
     5041 caacccatcg ttgttcgtgg ggtcatgaaa cccattccta ctctttataa acctcttatg
     5101 agtgtggata tcgaaaccca cgaaccttac aaggcaaccg tggagagaag tgatccgact
     5161 gctcttccag ctgcaggaat ggtcatggaa gcagttgtag caacggttct ggcgcaagaa
     5221 atcctcgaaa aattctcatc agataatctt gaggaactaa aagaagcggt agccaaacac
     5281 cgagactata caaagaacta ttaaggagtt cctatggcaa aaacaatcta tatcgcaggt
     5341 cttgggttga ttggagcctc tatggcactt ggtatcaaac gcgatcatcc agattatgaa
     5401 attttaggtt ataatcgtag tcaagcttcg agagatatcg ccttgaaaga aggcatgatt
     5461 gaccgtgcaa cggatgattt tgctagtttt gctcctttgg cagatgtcat tatcctcagc
     5521 ttgccaatca aacaaactat tgctttcatt aaggagttgg ccaatttgga tttgcgagaa
     5581 ggcgttatta tttcagatgc tggttcgacc aagtcaacca ttgtggatgc ggcggagcag
     5641 tatttggctg gcaagtctgt tcgctttgtc ggggcccatc ccatggctgg tagtcacaag
     5701 acaggggctg cttcggcaga tgtcaatctt tttgaaaatg cctattatat ctttacacct
     5761 tcaagcctga caagtcagga cacgcttaag gaaatgaagg atctgctttc aggtcttcat
     5821 gctcgtttta tcgagattga tgccaaggag catgatcgtg tcacttctca gattagccat
     5881 tttcctcata ttttggcttc tagtctcatg gagcagactg cggtctatgc tcaagagcat
     5941 gagatggcaa ggcgctttgc ggcaggtggt tttcgagata tgacccgaat tgcggaaagc
     6001 gagccaggaa tgtggacctc cattctcttg tccaatagcg agaccattct ggatagaatt
     6061 gaggatttca aggaacgttt ggaagtgatt ggtcaggcca ttagtaaggg agatgaagag
     6121 caaatttgga acttttttaa ccaagcgcgt gaacaacgcc agaccatgga aatccataag
     6181 cgtggtggtg tggatagctc ttacgacctc tatgttgacg ttcctgatga agaagatgtc
     6241 atcctgcgga ttttggaact gctacgtgga acttccttgg ttaacatcca catcaacgag
     6301 gaaaatcgtg aggatattca cggaatccta caaatttcat ttaaaaatgc tcaagacttg
     6361 gaaagagctg agcatctcat aacagaaaat accgactata cagtcgtcat caaataagga
     6421 gaagaacatg tcaaatattt acgatagtgc aaacgaactc agtcgcggtc tacgcggatt
     6481 accagaatac aaggctgtta aagcagctaa agatgcgatt gcagcagatg ctgaggcaag
     6541 caaaatcttt acagaatatc ttgcctttca agaggaaatt caaaaactag cacatacagg
     6601 tcaaatgcca gatgcgtcct tccaagctaa gatggaaggc tttggtaaac agattcaagg
     6661 aaatagcctc ttgtcagaat tctttaccaa gcaacaacaa ttggccattt acctttctga
     6721 cattgaaaaa attgtttttg aaccagtttc agaattgctg aaataagaaa agaacgatcc
     6781 taaagtcagg aatttttaag gaatttctgg ctttttatga taaaataggt aaaagtattg
     6841 caagtatgag gtccagtatg aaactaaaaa caaacattcg ccatttacat ggtagtatcc
     6901 gcgtcccagg tgacaagtct atcagccacc gttccattat ctttggaagt ttggctgagg
     6961 gtgagaccaa ggtttatgat attctgcgag gtgaagacgt tctttcgacc atgcaggttt
     7021 ttcgtgacct tggtgttgaa attgaggata aagatggggt tattaccatt caaggtgtag
     7081 gcatggctgg cttaaaagcg ccacaaaatg cccttaatat gggaaattct ggcacctcga
     7141 ttcgcctgat ttcaggtgtc cttgctggtg cagatttcga agtagagatg tttggagatg
     7201 atagtctttc caaacgtcct atggaccgtg tgacccttcc actgaaaaaa atgggcgtca
     7261 gcatttcagg gcaaactgaa cgagacttgc ctccccttcg cttaaaaggg acgaaaaacc
     7321 taagacctat tcattatgag ttgccaattg cctctgccca agtcaagtca gccttgatgt
     7381 ttgcagcctt acaagctaag ggggagtcag ttattatcga aaaagagtgc acccgtaatc
     7441 atactgaaga tatgttgaaa caatttggtg gtcatttaag tgtggacggt aagaaaatca
     7501 cagtccaagg gccacaaaaa ttgacaggac agaaggtggt cgtaccagga gatatttcca
     7561 gtgcagcctt ttggttagtc gcaggtttga ttgttccaaa ttctcgtcta gtgctgcaga
     7621 atgtggggat caacgaaact cgcaccggta ttattgatgt cattcgtgcc atgggtggaa
     7681 aattggaaat aactgaaatc gatccagtcg ctaaatcttc taccttgact gttgagtctt
     7741 ctgacttgaa aggaacagag attggtggcg ctttgattcc acgattgatt gatgaattgc
     7801 ccattattgc cctgcttgcg actcaagccc aaggtgtaac agttatcaag gatgctgagg
     7861 agctcaaggt caaggaaaca gaccgtattc aggttgtggc agacgcctta aatagtatgg
     7921 gagcagatat tactcctacg gcagatggga tgattatcaa agggaaatca gctcttcacg
     7981 gtgctagagt caatacgttt ggtgaccacc gtatcggcat gatgacagct atcgcagccc
     8041 tcttggttgc agatggagag gtggagcttg accgtgcaga agccatcaat accagctatc
     8101 ctagtttctt tgatgatttg gagagcttga ttcatggcta aggtgttatt agggtttatg
     8161 ggggctggaa aatcgactat tgcaagaggc ttggacccta attaccttga tatggatgct
     8221 ctgattgaga agcgcctagg tatgtccatt gcgaattttt tcgctgaaaa gggagaagca
     8281 gcctttcgtc aggtagaatc agaagtccta gctgatttac tacaaacaga ccaagtcgtg
     8341 tcaactggag gaggagtggt tatttctcag agaaatcgtg acttactcaa gactaataca
     8401 gataacatct acctgaaagc agattttgaa accctctacc aacgtatcgc agctgataag
     8461 gacaatcagc gaccgctttt tctaaataat agcaaggaag aactagtagc tatttttcaa
     8521 gaaagacagg cttggtatga ggaagtggct agtcgggttt tggatgtgac caagctaagc
     8581 ccagaggaaa ttatagagga actaagatga aaattgctta tctaggtccc aaaggatcat
     8641 tttcacacca cgttgtgcag acagcttttc ctcatgagga attgcaggct tttgccaaca
     8701 ttacagatgt catcaaggct tatgagcaag gattagtgga ctattctgtg gtgccagttg
     8761 aaaattctat tgagggtagt gttcatgaaa ccttggacta tctttttcat caggctcaca
     8821 tccaagcagt agcagaaatc gttcagccta ttcatcagca gttgatggtg gttccaggcc
     8881 atactaagat tgaaaagatt ttttcacatc cacaggcctt ggctcaagga aagaaattca
     8941 tcgatgaaca atatacagag gctcaaatcg aggtaacagc tagtacagct tatgcggccc
     9001 gttttatttc cgaacatcca gatcagccct ttgcagcaat tgcacctaga agttctgctg
     9061 aagaatatgg attggaactg attgccgagg atattcagga aatggaagcc aatttcacac
     9121 gtttctgggt tctaggagct gaaaagccta gtattccctt gcaagcacaa actgaaaaga
     9181 tgagtttggc cttgacatta cctgacaacc ttccaggtgc actttataag gccctgtcga
     9241 cctttgcttg gcgaggaatt gacttgacaa aaattgaaag tcgtccactc aagacagcac
     9301 tgggtgaata ctttttcatt atcgatgtgg attataccga taaggacttg gtccactttg
     9361 cccaaaaaga attagaagcg attggaatcc agtataaaat tctgggtgcc tatcctattt
     9421 atccaatatc agaccatgga aaggagagaa gatgagtaaa gaaaatccct taagtcatca
     9481 tgagcagttg cgttatgatt atttgctaaa aaatattcac tatctcaatg agagagaaaa
     9541 aaatgagttt gcctatttgc aagaaaagct aactcttgct aggggaaata gtagctctag
     9601 cttggaacaa gaaagagaag agcaggttga cttaccaagc tatgcgaacc ggagtcgctc
     9661 acaatccaaa tcacaagcac tctctttccc tccaaaaaag aaaagacgga agctccgtct
     9721 taaacgaatt tttatggtga ttttttcact tttggtctgt gtggctttgg ccatggtatt
     9781 catgtttttg cgtggttacc aagatgctag cgcaaagaaa actgctgatg cccgggcagc
     9841 tcaagtagaa gtctttaatg gtcaggacac tagagatgga gttaatattt taatcatggg
     9901 tactgatggt cgaatcggcc agaacagtgt tgagacacga actgactcta ttatggtatt
     9961 aaatgtcggg ggctcagata agaaaatgaa gctagtcagt ttcatgcgtg ataatttggt
    10021 ctatatagat ggttatagtc aagtgattaa cggtagaaaa cagacagata acaagttaaa
    10081 cgtagcctac gagttaggag aacaagaggg gcaaaaaggg gcagaaatgg ttcgccaagt
    10141 cttgaaagat aattttgact tggacattaa gtactacgcc ttggttgatt tccaggcctt
    10201 tgccacagcg attgacacgc ttttccctga tggggtgacg attgatgctc aattttcaac
    10261 attgaatggg cgtcccctaa cagaagctac agtcggagat gatttatacg ctaccgagac
    10321 tgagtctcca acccaaacca ttaaagtcgg aaaacagcag atgaatggct cgaccctgct
    10381 caattatgct cgtttccgtg atgatgatga ggcagattac ggccgtacaa aaagacagca
    10441 acaagtttta acagcaattt tagagcaaat taaagatccc actaaacttt tcactggttc
    10501 tgaagctctt ggaaaggttt ttgctatgac ctcaaccaac gtaccctata ctttcctcct
    10561 aacaaacggt ttatctgttt tggatggagc aaaaaatggt attgaaaaat tgacgattcc
    10621 agaactgggt gactgggtag atgcctatga tgtttatggg ggcttgggcc tgctggttga
    10681 tcaaaacaaa tatcaaacca agctcgctca aatgggctta agataagata atactcaatg
    10741 aaaatcaaag tgcaaactag gaagctagcc gcaggctgct aaaaacacag ttttgaggtt
    10801 gtagataaga ctgacgaagt cagttaccta tacctacggc aaggtgaagc tgacgtggtt
    10861 tgaagagatt ttcgaagagt ataagacaga aaaatcaaag tttgatagct atttggatag
    10921 cagtcaggct ttgatttttt acagtctgca atagattttc accccttgtt tgtggtataa
    10981 tgaaacgata cgatagaaag aataatgaac aatatgactg atttaaaagc aattcaggct
    11041 cgtagtctgg agatggctga atattttgtg gccttttgta aagaacatga tttgctctgt
    11101 tatctctgtg gcggaggcgc tattggtgcc cttcgaaaca agggatttat tccttgggac
    11161 gacgacctag acttttttat gcctcgtaaa gattatgaga aattagcaga attatggcct
    11221 cgttatgcag atgaacgtta tttcttgtca aagagtcaca aggattttgt tgatcgtaat
    11281 ctttttatta ccattcgtga caagaaaacc acctgtatca agccttatca gcaggatttg
    11341 gatttaccac atggtctggc cttggatgtt ttgcctttgg attattatcc gaaaaatcca
    11401 gatgagcgga aaaaacaggt tcgttgggcc ttgatttatt cactcttttg tgcgcaaact
    11461 attccagaaa agcatggtgc tctcatgaaa tggggaagtt gcattttact gggtttgact
    11521 ccaaaatctc tccgttatcg catctggaaa aaagctgaga aagaaatgac taagtatgat
    11581 ttggctgatt gtgatggcat tacagaatta tgctcaggtc ctggctacat gagaaacaag
    11641 tacccaatca catcttttga agacaatctt ttcttgccat ttgaaggaac agagatgcct
    11701 attccaatcg gctatgatgt ctatctcaga actgcttttg gggattatat gacgcctcca
    11761 ccagcagaca agcaggtacc gcatcatgat gctgtcatcg ctgatatgga taagtcttat
    11821 acagaataca agggagaata tggtggctaa gaaaaaaatc ttatttttta tgtggtcttt
    11881 ttctcttgga ggtggtgcag agaagattct atcaaccatt gtttcaaatc tggatccaga
    11941 aaagtatgat attgatattc ttgaaatgga gcactttgac aagggatatg aatctgttcc
    12001 aaagcatgta cgcattttaa aatcccttca agattatcgc caaaccagat ggttacgagc
    12061 ttttttgtgg agaatgagaa tttattttcc aagactggct cgtcgtttgc ttgtaaaaga
    12121 tgattatgat gttgaagttt cttttaccat tatgaatcca ccactgttgt tctctaaaag
    12181 aagagaagtc aagaagatat cttggattca tggaagtatt gaagaatttc ttaaggatag
    12241 ctctaaaaga gaatcacata gaagccagtt ggatgctgcg aatacaattg tagggatttc
    12301 aaaaaagacc agcaattcta tcaaggaagt ttatccagat tatgcttcta aattacagac
    12361 aatctacaat ggatatgatt ttcagactat tctagaaaaa tctcaagaga agatcgatat
    12421 cgagattgct cctcaaagta tctgtactat cggacggatt gaggaaaata agggttctga
    12481 ccgtgtagtg gaagtgatac gattattaca ccaagaggga aaaaactatc atctctattt
    12541 tatcggggct ggtgatatgg aagaggaact gaaaaaacga gtcaaagagt atgggattga
    12601 ggactatgta catttccttg gttatcaaaa aaatccttat cagtatctat ctcagacgaa
    12661 agttctcttg tctatgtcta aacaagaagg ttttcctgga gtgtatgtgg aggccttgag
    12721 tctgggactc ccttttatct ctacggacgt tggaggggct gaggaattat cccaagaagg
    12781 acgatttgga caaatcattg agagcaatca agaggcagct caggcgatta ctaattacat
    12841 gacttctgcc tcaaactttg atgtcgatga ggctagccaa ttcattcaac aatttacaat
    12901 tacaaaacaa atcgaacaag tagaaaaact attagaggag tagcatggaa actgcattaa
    12961 ttagtgtgat tgtgccagtc tataatgtgg cgcagtacct agaaaaatcg atagcttcca
    13021 ttcagaagca gacctatcaa aatctggaaa ttattcttgt tgatgatggt gcaacagatg
    13081 aaagtggtcg cttgtgtgat tcaatcgctg aacaagatga cagggtgtca gtgcttcata
    13141 aaaagaacga aggattgtcg caagcacgaa atgatgggat gaagcaggct cacggggatt
    13201 atctgatttt tattgactca gatgattata tccatccaga aatgattcag agcttatatg
    13261 agcaattagt tcaagaagat gcggatgttt caagctgtgg tgtcatgaat gtctatgcta
    13321 atgatgaaag cccacagtca gccaatcagg atgactattt tgtctgtgat tctcaaacat
    13381 ttctaaagga atacctcata ggtgaaaaaa tacctgggac gatttgcaat aagctaatca
    13441 agagacaaat tgcaactgcc ctatcctttc ctaaggggtt gatttacgaa gatgcctatt
    13501 accattttga tttaatcaag ttggccaaga agtatgtggt taatactaaa ccctattatt
    13561 actatttcca tagaggggat agtattacga ccaaacccta tgcaaagaag gatttagcct
    13621 atattgatat ctaccaaaag ttttataatg aagttgtgaa aaactatcct gacttgaaag
    13681 aggtcgcttt tttcagattg gcctatgctc acttctttat tctggataag atgttgctag
    13741 atgatcagta taaacagttt gaagcctatt ctcagattca tcgtttttta aaaggctatg
    13801 cttttgctat ttctaggaat ccaattttcc gtaaggggag aagaattagt gctttggccc
    13861 tattcataaa tatttcctta taccgattct tattactgaa aaatattgaa aaatctaaaa
    13921 aattacatta gaacgggggt gaccaagtga ttgatgggaa acgattatta tttagtttga
    13981 ccatagtcag ttataccttg acgatagtaa gtggaattgt gtatctgttt aataataata
    14041 atgttagctt actttctact ttattgttct tgttggttag tagcttaatt gcttgttgga
    14101 atgatatcaa gtattactta atccatttta ttttctattt aaccattttt gtatttctgg
    14161 tatcaagacc gaccattgat tattttaggg atggtgcttt ggatacctat catccaatag
    14221 cctatcgttt tgcctttata gttgttatgg tttcgattct gggcttgacc acaggaggcg
    14281 tcctggctcg ttacttcata gctaggaaga aaataaaagt agcaaatata ggaaattctc
    14341 taaaagaggt ttatatcaag cggttacgct ttgtatcact aggagttttt cttctaacct
    14401 atcctttcta tttcattcgg ttatttgaac ggctcttgta tcgtttgcag acttcctact
    14461 atgcctacta tgcaaatttt gaaagtaaac tgccttattt tacctacatt ttgtctacct
    14521 ttacggtcta tgcaatgtgt atgtatctgg caaccaagcc aaagaaattg caggccacag
    14581 cagtgcttgt ctcctttatt gcagctaata ctattcattt ggcaattggg acacgaaatc
    14641 cctttatttt aagtatttta tttgcttttg tttattactt tatgcgggag caaactgaaa
    14701 aaggaaaatg gattgggttt aaagaaaagt tagcgatttt tgtaggttct cctattctca
    14761 tgttagcgat gggagtactt aattatgtac gggataatgt ccaagtttcc catacaggtt
    14821 tctgggatat cttacttgac tttatctata aacaaggaac tagttttggt gttctggctc
    14881 gaggttttct atttaacagt agcctccctt accgagattt ccgtaatttt acttttggtc
    14941 ctgttcttga ttattttgca agggggagtt tgggagccat tttcggagga aaagcctttg
    15001 aacatacaac caatagtgtg gaactagcta ttgatagtaa tagttatgcc cacaatctat
    15061 cctatcttgt cttgaacaag gaatacttga aagggcatgg tatcggaagt agttatatca
    15121 tggagttgta taccgactat ggtatgattg gagtctttct gcttagtttc ttactcggcg
    15181 tattatttat agccatgctg caagtagcct atcgctcaag gacaatccta tttgctttat
    15241 ccctactcat cttgaataat ctattcttta tgccaagaag cagcttttca gaaagtttct
    15301 tcaatttatt tacaatgcaa ttctggggaa ttgttcttgt gattatattt gtagcaaaaa
    15361 tgcttacaaa ggaaaactag tatctactaa acaaaggaga aaaaaatcat gtttgaacat
    15421 tattcagtag ctgatttgtt tgcaaatctt tataaaaaac gaaaagcaaa tattttagct
    15481 ctcatcgctt tatttgctct cattgctgta ccatttacaa ttaaagcagt taggaataaa
    15541 aacactgtca aagatacaac aagttattca acttatctta tctataaaat cactcctcca
    15601 gaagattcgg ccaaaacgat tttgaatcat caaattggtg gttatagtga tttttatggg
    15661 aaattgattg atggtaattt gaatggagct tatcttttca atgatgtaga acccagtgag
    15721 ttgaaaaaaa ttgccagtga attagacacg acggaaacaa ccttgaaaaa ttcaacgaat
    15781 gactattggt ggaaaaaatt gaccgtctac tatatgattg acgatgcagg ggttggtgtg
    15841 aaaattttga catcaagtaa agatgccaat gacttgttag agaaaaaaat tgatgggttg
    15901 attgagaaat ttaaacatgc ttatgcaaat gtgaaaattg aaaaactgga aaccatcaac
    15961 tctaaagaat tgaacgcaaa tggtgaaaca gcgcttggct taaatgtgaa aaatctgatt
    16021 cttcgtttag ttgttattgg agtggtttgt gtgattttgg ttgtgatggg aaatgtgtta
    16081 gtttatctct ttaatccaac aatcaataga gtaggtgatt tttctcagta tcaaattgat
    16141 tttgtaacag agattacaac aattgctaac ctagcagatg ttttgtcata caaaaatact
    16201 ggacaggaat tgaccatcgt tagctcaaat aaagctatcc tagataaatt gaaacagagt
    16261 caagaagctt taaaaggaat gcattttgta gatttgcagg atgtatcatc tcttttggaa
    16321 agagatacag tccttcttgt tgaagagtac ggagtgactc gttataagaa atttgagcaa
    16381 agtcttcaaa ttctcagaaa cttaaatcgt tctatcctcg gtgtagcaac ctttaaatta
    16441 taagtattct gatgtatgag gtcttcaaaa tcggctaaga gctgattttg aaggcttttt
    16501 ctatctgtct gcagaaattt tcttttggag tctcctatag aaagacccta gggaaaatct
    16561 atccgtatag aggagccttc ttttgataaa atcgtaaaaa tctagtataa tagatagaac
    16621 tgaaagtatg aggttactag caatgaaaat gaaacaaatt agtgatacaa ctttaaaaat
    16681 cactatgtct ttagaggatt tgatggatcg tggaatggag attgctgact ttctcgttcc
    16741 tcaagaaaaa acagaagagt tcttttatgc tatcttggat gagctagaga tgcctgatag
    16801 ctttctggat acaggcatgt tgagcttccg tgtgactcca aaacctgata aggtagatgt
    16861 ctttgtgacc aagtcaaaga ttgaccaaaa tctagatttt gaagacttat cggatttgcc
    16921 agatatggaa gaattggctc aaatgtctcc agatgaattt atcaaaaccc tggaaaaaag
    16981 catcgcagac aaaaccaagg atgatatcga agccattcaa tctcttgagc aagttgaagc
    17041 caaggaagaa gagcaagagc aggctgaaca agaagctgag agtaagaaag aaccttacat
    17101 ctactacatc ctttcttttg ctaagttggc tgacttggta gtttttgcca agacagtgac
    17161 ttttgaaatg gaaacttctg aactctacaa aatgaacgag cgctattatt tgaccatttt
    17221 agtggatatt gaaaatcatc caagcccata tccagcttgg ctgttggccc gtatgcgcga
    17281 gtttgcagac gatagtgata tcagtcgctc agtcttacaa gagtatggtc aagtcttgat
    17341 gagtcacgat gcagtgctca atctgcaaaa aatcggctaa tcctttctgg aaagctattt
    17401 tcagatttta agaagagcga atcgtctgat tcgttttttc tttttatact gaaatagtga
    17461 tttactataa taggaatttt cacaaaattc tgttataatg gctatattag aaaatttcga
    17521 ggagataaag atgacagtta aaattgcttt actaggattt ggtaccgttg caagtggtgt
    17581 gcctttcctc ctaaaggaaa atggaggaaa aatcaatcaa tcagcacatt cagatatcaa
    17641 agttgctaag gtattggtca aggatgaaga tgaaaaaaat cgcttgcttg cagcagggaa
    17701 tgactttaac tttgtaacca atgtggatga tattttatca gaccaggata ttactatcgt
    17761 agtggaattg atggggcgta ttgagcctgc taaaaccttt atcactcgtg ccttggaagc
    17821 tggaaaacac gttgttactg ctaacaagga ccttttagct gtccatggcg cagaattgct
    17881 agaaatcgct caagctaaca aggtagcact ttactacgaa gcagcagttg ctggtgggat
    17941 tccaattctt cgtactttag caaattcctt ggcttctgat aaaattacgc gcgtgcttgg
    18001 agtagtcaac ggaacttcca acttcatggt gaccaagatg gtggaagaag gctggtctta
    18061 cgatgatgct cttgcggaag cacaacgtct aggatttgca gaaagcgatc cgacgaatga
    18121 cgtagatggg attgatgcag cctacaagat ggttattttg agccaatttg cctttggcat
    18181 gaagattgcc tttgatgatg tagcccacaa gggaatccgc aatatcacac cagaagacgt
    18241 agctgtagct caagagtttg gttacgtagt gaaattggtt ggttctattg aggaaacttc
    18301 ttcaggtatt gctgcagaag tgactccaac cttcctacct aaagcgcacc cacttgctag
    18361 tgtgaatggc gtaatgaacg ctgtctttgt agaatctatc ggtattggtg agtctatgta
    18421 ctacggacca ggtgcgggtc aaaaaccaac tgcaacaagt gttgtagctg atattgtccg
    18481 tatcgttcgt cgtttgaatg atggtaccat tggcaaagac ttcaacgaat atagccgtga
    18541 cttggtcttg gcaaatcctg aagatgtcaa agcaaactac tatttctcaa tcttggctcc
    18601 agactcaaaa ggtcaggtct tgaagttggc tgaaatcttc aatgctcaag atatttcctt
    18661 taagcaaatc cttcaagatg gcaaagaggg tgacaaggcg cgtgtcgtta tcatcacaca
    18721 caagattaat aaagcccagc ttgaaaatgt ctcagctgaa ttgaagaagg tttcagaatt
    18781 cgacctcttg aataccttca aggtgctagg agaataagat gaagattatt gtacctgcaa
    18841 ccagtgccaa tatcgggcca ggttttgact cggtcggtgt agctgtaacc aagtatcttc
    18901 aaattgaggt ctgcgaagaa cgagatgagt ggctgattga acaccagatt ggcaaatgga
    18961 ttccacatga tgagcgtaat ctcttgctca aaatcgcttt gcaaattgta ccagacttgc
    19021 aaccaagacg cttgaaaatg accagtgatg tccctttggc gcgcggtttg ggttcttcta
    19081 gctcggttat cgttgctggg attgaactag ccaaccaact gggtcaactc aacttatcag
    19141 accatgaaaa attgcagtta gcgaccaaga ttgaagggca tcctgacaat gtggctccag
    19201 ccatttatgg taatctcgtt attgcaagtt ctgttgaagg gcaagtctct gctatcgtag
    19261 cagactttcc agagtgtgat tttctagctt acattccaaa ctatgaatta cgtactcgcg
    19321 acagccgtag tgtcttgcct aaaaaattgt cttataagga agctgttgct gcaagttcta
    19381 tcgccaatgt agcggttgct gccttgttgg caggagacat ggtgaccgct gggcaagcaa
    19441 tcgagggaga cctcttccat gagcgctatc gtcaggactt ggtaagagaa tttgcgatga
    19501 ttaagcaagt gaccaaagaa aatggggcct atgcaaccta cctttctggt gctgggccga
    19561 cagttatggt tctggcttct catgacaaga tgccaacaat taaggcagaa ttggaaaagc
    19621 aacctttcaa aggaaaactg catgacttga gagttgatac ccaaggtgtc cgtgtagaag
    19681 caaaataaag aatagaagat aggatgggga aactcttgac cagagggttt catatccttt
    19741 ttgtgaaaag aagtttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag
    19801 gttgctcaaa gcactgcttt gaggttgtag atagagctga cgtggtttga agagattttc
    19861 gaagagtatt agttaaaaac gtgataaagg agaaataaaa atggcagaaa tttatctagc
    19921 aggtggttgt ttttggggcc tagaggaata tttttcacgc atttctggag tgctagaaac
    19981 cagtgttggc tacgctaatg gtcaagtcga aacgaccaat taccagttgc tcaaggaaac
    20041 agaccatgca gaaacggtcc aagtgattta cgatgagaag gaagtgtcac tcagagagat
    20101 tttactttat tatttccgag ttatcgatcc tctatctatc aatcaacaag ggaatgaccg
    20161 tggtcgccaa tatcgaactg ggatttatta tcaggatgaa gcagatttgc cagctatcta
    20221 cacagtggtg caggagcagg aacgcatgct gggtcgaaag attgcagtag aagtggagca
    20281 attacgccac tacattctgg ctgaagacta ccaccaagac tatctcagga agaatccttc
    20341 aggttactgt catatcgatg tgaccgatgc tgataagcca ttgattgatg cagcaaacta
    20401 tgaaaagcct agtcaagagg tgttgaaggc cagtctatct gaagagtctt atcgtgtcac
    20461 acaagaagct gctacagagg ctccatttac caatgcctat gaccaaacct ttgaagaggg
    20521 gatttatgta gatattacga caggtgagcc actctttttt gccaaggata agtttgcttc
    20581 aggttgtggt tggccaagtt ttagccgccc gatttccaaa gagttgattc attattacaa
    20641 ggatctgagc catggaatgg agcgaattga agttcgttct cgttcaggca gtgctcactt
    20701 gggtcatgtt ttcacagatg gaccgcggga gttaggcggc ctccgttact gtatcaattc
    20761 tgcttcttta cgctttgtgg ccaaggatga gatggaaaaa gcaggatatg gctatctatt
    20821 gccttactta aacaaataaa acagagagtg gggcttccca ctttcttcat ttctagaata
    20881 tgaatagaag ggatttatga aacacctatt atcttacttc aaaccctaca tcaaggaatc
    20941 aattttagcc cccttgttca agctgttaga agctgttttt gagctcttgg ttcccatggt
    21001 gattgctggg attgttgacc aatctttacc tcagggagat caaggtcatc tctggatgca
    21061 gattggcctg ctccttatct ttgcagtaat tggcgtttta gtggccttga tagctcaatt
    21121 ttactcagca aaggcagcag taggttttgc taaggaattg acaaacgatc tttatcgtca
    21181 tattctttcc ttgcccaagg acagcagaga ccgtctgaca acttctagtt tggtcactcg
    21241 cttgacttcg gatacctacc agattcagac tggtatcaat caattcctgc gtctcttttt
    21301 acgagcgccc attatcgttt ttggtgccat ttttatggct tatcgaatct cagctgagtt
    21361 gactttctgg ttcttagtct tggttgccat tttgaccatt gtcattgtag ggttatctcg
    21421 attggtcaat cctttctaca gtagtctcag aaagaaaacg gaccaactgg ttcaggaaac
    21481 gcgccagcaa ttgcaaggga tgcgggttat tcgtgctttt ggtcaagaaa aacgagagtt
    21541 acagattttt caaaccctta accaagttta tgctagatta caagaaaaga caggtttctg
    21601 gtctagttta ttaacacctc tgacctatct gattgtcaat ggaactcttc tcgttattat
    21661 ctggcaaggc tatatttcaa ttcaaggagg agtgctcagt caaggtgctc tcattgctct
    21721 tatcaattac ctcttacaga ttttggtgga attggtcaag ctagccatgt tgatcaattc
    21781 cctcaaccag tcctatatct cagtcaagcg aatcgaggaa gtctttgttg aggctccaga
    21841 ggatatccat tcagagttag aacaaaagca agctaccaga gataaggttt tacaagtcca
    21901 agaattgact tttacctatc ctgatgcggc ccagccttct ctgagataca tttcctttga
    21961 tatgactcaa ggacaaattc taggtatcat cgggggaact ggttctggta aatcaagctt
    22021 ggtgcaactc ttacttggac tttatccagt agacaagggg aacattgacc tttatcaaaa
    22081 tggacgtagt cctcttaatt tggagcagtg gcggtcttgg attgcctatg tacctcaaaa
    22141 ggtcgaactc tttaaaggaa ccattcgttc caacttgact ctaggtttca atcaagaagt
    22201 atctgaccag gaactctggc aggccttgga gattgcgcaa gctaaggatt ttgtcagtga
    22261 aaaggaagga ctcttggatg ctctagttga ggcagggggg cgaaatttct caggtggaca
    22321 aaaacaaaga ttgtctatcg cccgagcagt cttgcgccaa gctccgtttc tcatcctaga
    22381 tgatgcaacc tcggcactgg ataccattac agagtccaag ctcttgaaag ctattagaga
    22441 aaattttcca aacacgagct taattttgat ctctcaacga acctcaactt tacagatggc
    22501 ggaccagatt ctcctcttgg aaaaaggtga gttgctagct gttggcaagc acgatgactt
    22561 gatgaaatcc agccaagtct attgtgaaat caatgcatcc caacatggaa aggaggacta
    22621 gaatgaaacg acaaactgta aaccagacgc tcaaacgttt agccgtagat ttagcaagcc
    22681 atcctttcct ccttttccta gcctttctag gaactattgc tcaagttggc ttatcaattt
    22741 acctacctat tctgattggg caggtcattg accaagtcct agtggctggt tcatcaccag
    22801 ttttttggca gatttttctc cagatgctct tggtggtaat aggaaatact ctggtacaat
    22861 gggccaatcc tctcctctat aatcgtctaa tcttctctta taccagagat ttacgggagc
    22921 gaatcatcca taagctccat cgtttaccga ttgcctttgt agataggcaa ggtagtggag
    22981 agatggttag tcgtgtaacc acggacatcg aacagttggc agctggcttg accatgattt
    23041 ttaaccaatt tttcattggt gttttgatga ttttggtcag tattctagcc atgctccaaa
    23101 ttcatctcct catgactctc ttagtcttgc tgttgacgcc actgtccatg gtgatttcac
    23161 gctttattgc caagaaatcc tatcatctct tccagaagca aacagagacg aggggaattc
    23221 agactcagtt gattgaagaa tcgcttagtc agcagactat aatccagtcc ttcaatgctc
    23281 aaacagaatt tatccaaaga ttgcgtgagg ctcatgacaa ctactcaggc tattctcagt
    23341 cagccatctt ttattcttca acggtcaatc cttcgactcg ctttgtaaat gcactcattt
    23401 atgccctttt agctggagta ggagcttatc gtatcatgat gggttcagcc ttgaccgtcg
    23461 gtcgtttagt gacttttttg aactatgttc agcaatacac caagcccttt aacgatattt
    23521 cttcagtgct agctgagttg caaagtgctc tggcttgcgt agagcgtatc tatggaatct
    23581 tagatagccc tgaagtggct gaaacaggta aggaagtctt gacgaccagt gaccaagtta
    23641 agggagctat ttcctttaaa catgtctctt ttggctacca tcctgaaaaa attttgatta
    23701 aggacttgtc tatcgatatt ccagctggta gtaaggtagc catcgttggt ccgacaggtg
    23761 ctggaaaatc aactcttatc aatctcctta tgcgttttta tcccattagc tcgggagata
    23821 tcttgctgga tgggcaatcc atttatgatt atacacgagt atcattgaga cagcagtttg
    23881 gtatggtgct tcaagaaacc tggctcacac aagggaccat tcatgataat attgcctttg
    23941 gcaatcctga agccagtcga gagcaagtaa ttgctgctgc caaagcagct aatgcagact
    24001 ttttcatcca acagttgcca cagggatacg ataccaagtt ggaaaatgct ggagaatctc
    24061 tctctgtcgg ccaagctcag ctcttgacca tagcccgagt ctttctggct attccaaaga
    24121 ttcttatctt agacgaggca acttcttcca ttgatacacg gacagaagtg ctggtacagg
    24181 atgcctttgc aaaactcatg aagggccgca caagtttcat cattgctcac cgtttgtcaa
    24241 ccattcagga tgcggattta attcttgtct tagtagatgg tgatattgtt gaatatggta
    24301 accatcaaga actcatggat agaaagggta agtattacca aatgcaaaaa gctgcggctt
    24361 ttagttctga ataagccatt ctcttttgaa agtttatgga cgaaaaaagt tgccttcgag
    24421 tgactttttt gttacaatag ctagaaaaat tgttcactgt aatactcaat gaaaatcaaa
    24481 gagcaaacta ggaagctagc cgtaggttgc tcaaagcaca gctttgaggt tgtagataag
    24541 actgacgaag tcagttcaaa acactgtttt gaggttgcag atagaactga cgaagtcagc
    24601 tcaaaacact gttttgaggt tgcagataga actgacgaag tcagtaacca cacctacggc
    24661 aaagtgaatc tgaagtggtt tgaagagagt acaacttgtc ttttagaaaa ggagcctata
    24721 atgaaagtct ttcagcatgt aaatatcgtg acttgtgatc aagatttcca tgtttatctt
    24781 gatggaatct tagcagtcaa ggattctcaa atcgtctatg tcggtcaaga taagccagcg
    24841 tttttagagc aagctgagca gattatagac tatcagggag cttggattat gcctggtttg
    24901 gtcaattgtc acacccattc tgcaatgaca ggtctgagag ggatccgaga tgacagcaat
    24961 ctccatgaat ggctcaatga ctatatttgg ccagcagaat ctgagtttac tcccgacatg
    25021 actaccaatg cggtcaaaga agccctgaca gagatgctcc agtcaggaac aacaaccttt
    25081 aacgatatgt ataatcccaa tggtgtggat atccagcaaa tttatcaggt ggtgaaaact
    25141 tccaagatgc gttgttattt ttctccgact ctcttttctt cagagacaga aacaactgct
    25201 gagactataa gtagaactcg atccatcata gacgaaatct taaaatataa aaatccaaat
    25261 ttcaaggtta tggtagcacc tcattctccg tatagctgca gtagagactt gctggaagcg
    25321 agtttggaaa tggcaaaaga gctaaatatt ccgctccatg tccatgtggc ggagaccaag
    25381 gaggagtcag gaattatcct caaacgatac ggcaaacgcc cccttgcttt tcttgaagaa
    25441 ctgggttatt tagatcatcc gtccgtattt gctcacgggg tcgaattaaa cgagagagaa
    25501 attgaacgct tggcatcttc tcaagtggct atcgcccaca atcctatcag taacctcaaa
    25561 ctggcatcag gaattgctcc aattatccag ctccaaaaag cgggagtagc agtcggaatt
    25621 gcgactgact cggttgcttc caataacaat ctagatatgt ttgaggaagg aaggactgca
    25681 gctcttcttc agaagatgaa aagtggggat gccagccagt ttccaatcga aacagctctc
    25741 aaggtactga caatcgaagg ggctaaggtc cttggaatgg aaaatcagat aggaagtctg
    25801 gaagtcggca agcaagcaga ttttctggtc attcaaccac aagggaaaat tcatctccaa
    25861 cctcaggaaa atatgctgtc tcacctggtt tatgcagtta aatctagtga tgtagatgat
    25921 gtttatatcg ccggagaaca ggttgttaag caaggtcaag tcctgacagt agaactttaa
    25981 aagaaaaatt acgaaaaatt ttaaaaaaag tttgcaaaaa tcttgcattc tttttttgac
    26041 tatgctatac ttatatacgg tttaaaaaaa ctgcctaaga cagtagggga gctcgactca
    26101 taaatatcct accgaggaca aaacgtatca tgtaaaaaga agcgtattgt actttcgtgt
    26161 ctaggtttgg gcgcgttttt ctttttgaaa aattccccaa gcaaaataat tacggaggtg
    26221 aacacactaa tgagtgaagc aattattgct aaaaaagcgg aactagttga cgtagtagct
    26281 gaaaaaatga aagctgctgc atctatcgtc gttgtagacg ctcgtggttt gacagttgag
    26341 caagatacag ttcttcgtcg tgagcttcgt ggaagcgaag ttgagtataa agttattaaa
    26401 aactcaatct tgcgtcgtgc agctgaaaaa gctggtcttg aagatcttgc atctgtattt
    26461 gttggaccat ctgcagtagc attttctaat gaagatgtta tcgcaccagc gaaaatcttg
    26521 aacgactttt ctaaaaacgc tgaagcactt gaaattaaag gtggtgcaat cgaaggcgct
    26581 gtcgcatcta aagaagagat tcttgcactt gcaactcttc caaaccgcga aggacttctt
    26641 tctatgctcc tttctgtact tcaagcgcca gtgcgcaacg ttgctcttgc agtcaaagcg
    26701 gttgcagaaa gcaaagaaga cgcggcttaa tcttaagcta cacagcgtag cctagctacg
    26761 aaaaaaacta ttataaaatt taaaacttat ttggaggaaa taacaatggc attgaacatt
    26821 gaaaacatta ttgctgaaat taaagaagct tcaatccttg aattgaacga ccttgtaaaa
    26881 gctatcgaag aagaatttgg tgtaactgca gctgctcctg tagctgttgc tgcagctgat
    26941 gcagctgatg ctggtgctgc taaagattca ttcgacgttg aattgacatc tgcaggcgac
    27001 aaaaaagttg gcgttatcaa agttgtacgt gaaatcactg gtcttggtct taaagaagct
    27061 aaagaacttg ttgacggtgc accagcactt gttaaagaag gcgttgcaac tgcagaagct
    27121 gaagaaatca aagctaaatt ggaagaagct ggagcttcag ttactcttaa ataatagagt
    27181 atcgcaattt gattgcggaa tccctattta ccagtctttg agagcgataa gcgattgata
    27241 gaaactgata aattgatttg gtttcctgcc aaaaattctt tggcaggatt tttgttttaa
    27301 taaactttcg ggggtagaca ctagattgtc tacccctttt tttgtgtttc ggaggtaatt
    27361 atgcaaaagg aaggacagtc atcacgtcaa ttcgtgaaga gtcatctcat gactatcatg
    27421 ggagttgata ttgtaaaagc aactcagtta gttgatgaaa tggaacaagt aggtttaatc
    27481 cgatttgatg aatttggaaa tgttggaatt ttagtcttgg agggacaata atgaagcgta
    27541 ttaccgctaa tcaatatcag acatcagagc gttattataa gctccccaaa cttttatttg
    27601 agagtgaacg gtataagaat atgaaactgg aggttaaggt ggtttactca gttttaaaag
    27661 atcggttgga gttttctttg agcaaaggtt ggattgatga ggatggggct atttatttga
    27721 tttattccaa ttcaaatttg atggcacttt taggctgttc aaagtcaaaa ttactctcca
    27781 tgtgagtttg aagtgacatt tttagatgat taccataaaa aacataacta cccactattt
    27841 tacgaatcct atcttcaaaa cgttatggaa ttccttgaaa gtcaagacat aaagaatggg
    27901 gttgatgcct ttgtagatga tcatcaaaat ctcgtttttg ttttatatgg acaaggctat
    27961 cgagccgagg gaaaagaggg aatacttaca acccaagtaa ctgtaaaagc ttatgatgaa
    28021 gacaagaaac cgattaactt cgcaaattta ttagattcct taatcgtgtc agaatatcaa
    28081 atggaaccga atctttggga ggtctcccat gattgatctc tatctaagta aaaatagaca
    28141 aagaaatcaa cttcttttag atttcttcca aaactatggc atagaggtat cttgtcattc
    28201 agtttctgaa atgacaaagg acaaattaat tgagatgatg agctattctt cagattgttt
    28261 tgagttttta tctcccaatt tattgcgatt taagaaccgt gacaatctaa gattaacgga
    28321 tttcgttgag ataattttaa aaaatcctga actaaccatc agacttcctc ttgtggtttc
    28381 aaataagcgg gtttatccaa gtctgaattt ggaagaggct agagctctat tgccaagaga
    28441 tacgaaacaa ttgatttaca tggcacaaac acattattta tataactaaa ggagaagcaa
    28501 tatggctgaa cgattttggg agaacttgtc cattattttg gctgaaagaa atatcagctg
    28561 gattgagtta accagaaaaa tgtttgcggg agagtttcac tatccaagtg aattgaatcg
    28621 tttgtatcaa aagattcgcc actagaagat ggaacaatga atgcctcaaa gtccatgggt
    28681 agaaagaatt gtgcaggtat tagatttaga ttatgaagat ttatttcgga ggtaactatg
    28741 aaaagaataa ttccagttta tatattccaa caagtaaatg tcctattggt atctctatac
    28801 ttattgaaat ttctttgtat cggtgagtta actatactac agattctcta tggttcgtca
    28861 ctcatttctt ttttatggat gtatggccaa cgcaaacaag cgcataaggt caatatgaaa
    28921 tctaggatga aatggcttgg tgttgaattt gttagcctac tgattataag tctatgtttt
    28981 agtctgattc atgctcaagg aagcacgaat caagcaaact taattggcct tcaacatcaa
    29041 attccttggt tttcattttt attgttctta atcaatgcga gtatggttga agaatttctg
    29101 tatcgagaaa ttttatggaa tttggtcaga aatttagata ttcgagttgc tttgacaagt
    29161 gttttatttg ccttagcaca tcatacagga accattctag cttggtgttt gtatgtttca
    29221 cttgggatgt ttttaggtat ggtgcgctat aaatctgact tatggggcag tatgggacta
    29281 catttggtgt ggaacctact agtttatagt ttgctgcttt tttaaaatag gtaacctgat
    29341 ttttaggtaa cttctaaaac taacttccag ttttgggaga gagatggaag ttactttgaa
    29401 aagttacgga aacattattt tctatgtgac aacattgtat cattgcttgc attttactgc
    29461 tggagagagt ataatgaagg tggataaagc acttaatcct aaaaatttaa ataggaggag
    29521 ttagctatgg cagaagaagt attaaatctt taattagtat ctgttcaagt tgacgaaaca
    29581 gatgaagttg atggaatgcg atttagtaca ttcagtacaa accgttgcgg taactggagt
    29641 gcttttagtt gggaaaattg ttaattcatt taaattgtaa actttagaga ttctctggag
    29701 ttatggatct cgttccaata tgtgcacgtt ggaatgtcag tgcttatatg gggggaatcc
    29761 aaaggattct ccctttttat tttaataagt ctgtctagct atagatatat taagtttgat
    29821 agaatttctt ggagattttg ttatggatta taatttcaat ttggagcatc ctttcttttt
    29881 cactaataat gattatagta cagatactag cataaagtac taagtaagtc tgccttttaa
    29941 ttggcacgaa gtaatgaata atgatgagtg ggtttatcaa taccctattg gaaaatttgt
    30001 tgaaagacaa gggtggaaaa tacacattag ttcagagtat aatagttcac acgaattgtt
    30061 acaagatgta gcaaaaattt gccatgaaat gcgaattcca tttaaacatc ttagtacaga
    30121 agacaaattt atcatgcgaa acgggaaatt ggttagtcga ggattttctg gtaaatttat
    30181 tacatgttat ccaaatcaaa atgaattaga gtcggttttg caaaggttag aaagtgcctt
    30241 aaagcaatat aatgggccat atattttaag cgataaacgt tgggatgaag caccaatata
    30301 tctgaggtat ggtgtgttta ggccgtcaag ggatgatgaa aagaaggttg ttattgatga
    30361 attaattgtt ggcgatgaag ttgttaaaga tgaacgttta ccagtattta aaattccaaa
    30421 aggtatagtg ccccctgact ttttgaataa atggcttgac aagaaagata aaaaacaggg
    30481 agactttccc tttattatag ataatgcaat tagattttca aacagtggtg ggatatataa
    30541 tgctagacta aaagaagatg ggaaaaaaat aattttaaaa gaggctagac cgtatacagg
    30601 tctaggattt gatggtactt attcttcaga gagattagct tcggagtgca aagcactaaa
    30661 aattctaaat gaatggagtg agatgcctaa aatatactgg tacggtaaga tctgggagca
    30721 caccttctta ggaattgaac atatgaaggg cgttccacta aatagatggg ttaccaataa
    30781 ttttccttta tatgaagttg ttgataagac caaagattat ctattgagag tttcaaagat
    30841 agtagaaaaa ctcatcgatt taacgaataa gtttcattct gaaaatgtat atcatcaaga
    30901 tttacattta ggaaatatct tggttaagga tgaagatgag attagtataa tagactggga
    30961 acaggctgtc ttttcgaatg atgaaaaagt tgtacataaa gttgcagccc ctggttttag
    31021 agcatggcga gaaacacttc ccagtgagat agattggtat ggtattagac aaatagctca
    31081 ttatttatac atgccactag taactacatc ggatttgaca tacaactatg taagtcaaac
    31141 caggatagaa ggaaaaaaac tatttgagtc tttgggttat acaagagaac atatagatta
    31201 tgtagaaagt ttattgtcat atctagattc taaatgtcca cagattgaga atatttccag
    31261 gaaaaaagtt ttaaaaccca tgcatgagat tagaactatc gagagtgagc aagatataca
    31321 agattttatt ataaaagctt ttcttttagt gaactgatag gtattttctt agcaaacgat
    31381 aaagttttag ggccgataca atcaattgcc tattcattaa ataagataaa tacaaccaaa
    31441 gatttaagga aaccgttttt aaaatactta agtggagaga agaattttat agacgctgaa
    31501 catgataata acggactgta tacttcatca atagatgaga tacacatgaa agatgttgta
    31561 tattctatta caccagaaaa taaattaagt attgacttct catttaagtc accatttagg
    31621 gtattattaa caggaacttc tggtagtggg aaaacaacga ttttaaattt aattaatggt
    31681 tctttaaagc cacaaaaagg ttatgtaaat ttgttatcac atgggaaaaa gagttcagat
    31741 tcaataccaa cagttgatca gacaccatat atttttgaca ctactattcg tgagaacgta
    31801 actttatttc aaaatgaata tttttcagat gatcagataa ttgaggtgtt aaaaaaggta
    31861 aatctatat
//
LOCUS       DAVMAH010000025        30763 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVMAH010000025 DAVMAH010000000
VERSION     DAVMAH010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30763
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.025"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            133..1662
                     /gene="rlrA"
                     /locus_tag="VYO94_001068"
     CDS             133..1662
                     /gene="rlrA"
                     /locus_tag="VYO94_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus transcriptional regulator RlrA"
                     /protein_id="HEV1759715.1"
                     /translation="MLNKYIEKRITDKITILNILLDIRSIELDELSTLTSLQSKSLLS
                     ILQELQETFEEELTFNLDTQQVQLIEHHSHQTNYYFHQLYNQSTILKILRFFLLQGNQ
                     SFNEFTQKEYISIATGYRVRQKCGLLLRSVGLDLVKNQVVGPEYRIRFLIALLQFHFG
                     IEIYDLNDGSMDWVTHMIVQSNSQLSHELLEITPDEYVHFSILVALTWKRREFPLEFP
                     ESKEFEKLKNLFMYPILMEHCQTYLEPHANMTFTQEELDYIFLVYCSANSSFSKDKWN
                     QEKKTHTIQLILQHTRGKHLLSKFKNILGNDISNSLSFLTALTFLTRTFLFGLQNLVP
                     YYNYYEHYGIESDKPLYHISKAIVQEWMTEQKIEGVIDQHRLYLFSLYLTETIFSSLP
                     AIPIFIILNNQADVNLIKSIILRNFTDKVASVTGYNILISPPPSEEHLTEPLIIITTK
                     EYLPYVKKQYPKGKHHFLTIALDLHVSQQRLIYQTIVDIRKEAFDKRVAMIAKKAHYL
                     L"
     gene            1927..3189
                     /locus_tag="VYO94_001069"
     CDS             1927..3189
                     /locus_tag="VYO94_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1759716.1"
                     /translation="MEHINHTTLLIGIKDKNITLNKAIQHDTHIEVFATLDYHPPKCK
                     HCKGKQIKYDFQKPSKIPFIEIGGFPSLIHLKKRRFQCKSCRKVTVAETTLVQKNCQI
                     SEMVRQKIAQLLLNREALTHIASKLAISTSTSTVYRKLKQFHFQEDYTTLPEILSWDE
                     FSYQKGKLAFIAQDFNTKKIMTILDNRRQTTIRNHFFKYSKEARKKVKVVTVDMSGSY
                     IPLIKKLFPNAKIVLDRFHIVQHMSRALNQTRINIMKQFDDKSLEYRALKYYWKFILK
                     DSRKLSLKPFYARTFRETLTPRECLKKIFTLVPELKDYYDLYQLLLFHLQEKNTDQFW
                     GLIQDTLPHLNRTFKTTLSTFICYKNYITNAIELPYSNAKLEATNKLIKDIKRNAFGF
                     RNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(3247..5571)
                     /gene="pflB"
                     /locus_tag="VYO94_001070"
     CDS             complement(3247..5571)
                     /gene="pflB"
                     /locus_tag="VYO94_001070"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV1759717.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            5966..7027
                     /gene="dinB"
                     /locus_tag="VYO94_001071"
     CDS             5966..7027
                     /gene="dinB"
                     /locus_tag="VYO94_001071"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV1759718.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(7174..8019)
                     /locus_tag="VYO94_001072"
     CDS             complement(7174..8019)
                     /locus_tag="VYO94_001072"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV1759719.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            8275..9225
                     /locus_tag="VYO94_001073"
     CDS             8275..9225
                     /locus_tag="VYO94_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEV1759720.1"
                     /translation="MPYVGIDVAKNKHDVTALNVQGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYNPLLIKKFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHNNRQVELKILTRHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAPRSIGTT
                     SPAREFEIIENIKHYKRLIDKAEKCVNDLMAELNSVITTVTGIGNRLGAVILAEIQNI
                     HAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLR"
     gene            complement(9604..11493)
                     /locus_tag="VYO94_001074"
     CDS             complement(9604..11493)
                     /locus_tag="VYO94_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV1759721.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEATLSNLFADYKVSDSLYRRA
                     KAADEKRIQARGIQLKSSFEEVLNQMQEGVRKRVVFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLQLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINFYVAYGWHSMFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            11631..13196
                     /locus_tag="VYO94_001075"
     CDS             11631..13196
                     /locus_tag="VYO94_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1759722.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIELRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNAYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            13196..13936
                     /locus_tag="VYO94_001076"
     CDS             13196..13936
                     /locus_tag="VYO94_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1759723.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(14045..14260)
                     /locus_tag="VYO94_001077"
     CDS             complement(14045..14260)
                     /locus_tag="VYO94_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759724.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(15131..16381)
                     /gene="ilvA"
                     /locus_tag="VYO94_001078"
     CDS             complement(15131..16381)
                     /gene="ilvA"
                     /locus_tag="VYO94_001078"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV1759725.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(16431..16787)
                     /locus_tag="VYO94_001079"
     CDS             complement(16431..16787)
                     /locus_tag="VYO94_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1759726.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(17025..17261)
                     /locus_tag="VYO94_001080"
     CDS             complement(17025..17261)
                     /locus_tag="VYO94_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759727.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(17368..18390)
                     /gene="ilvC"
                     /locus_tag="VYO94_001081"
     CDS             complement(17368..18390)
                     /gene="ilvC"
                     /locus_tag="VYO94_001081"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1759728.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYIVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(18456..18932)
                     /gene="ilvN"
                     /locus_tag="VYO94_001082"
     CDS             complement(18456..18932)
                     /gene="ilvN"
                     /locus_tag="VYO94_001082"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV1759729.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(18925..20625)
                     /locus_tag="VYO94_001083"
     CDS             complement(18925..20625)
                     /locus_tag="VYO94_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV1759730.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(20826..22493)
                     /locus_tag="VYO94_001084"
     CDS             complement(20826..22493)
                     /locus_tag="VYO94_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV1759731.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(22496..22861)
                     /locus_tag="VYO94_001085"
     CDS             complement(22496..22861)
                     /locus_tag="VYO94_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1759732.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(23018..23206)
                     /locus_tag="VYO94_001086"
     CDS             complement(23018..23206)
                     /locus_tag="VYO94_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV1759733.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(23322..23807)
                     /locus_tag="VYO94_001087"
     CDS             complement(23322..23807)
                     /locus_tag="VYO94_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV1759734.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(24249..25793)
                     /locus_tag="VYO94_001088"
     CDS             complement(24249..25793)
                     /locus_tag="VYO94_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV1759735.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            26006..26308
                     /gene="gatC"
                     /locus_tag="VYO94_001089"
     CDS             26006..26308
                     /gene="gatC"
                     /locus_tag="VYO94_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV1759736.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            26308..27774
                     /gene="gatA"
                     /locus_tag="VYO94_001090"
     CDS             26308..27774
                     /gene="gatA"
                     /locus_tag="VYO94_001090"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV1759737.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQVAAAFEATTDYHKQQPVIFGGDN"
     gene            27774..29216
                     /gene="gatB"
                     /locus_tag="VYO94_001091"
     CDS             27774..29216
                     /gene="gatB"
                     /locus_tag="VYO94_001091"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV1759738.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISNEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            29345..29905
                     /gene="efp"
                     /locus_tag="VYO94_001092"
     CDS             29345..29905
                     /gene="efp"
                     /locus_tag="VYO94_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV1759739.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            29927..30316
                     /locus_tag="VYO94_001093"
     CDS             29927..30316
                     /locus_tag="VYO94_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1759740.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            30309..30731
                     /gene="nusB"
                     /locus_tag="VYO94_001094"
     CDS             30309..30731
                     /gene="nusB"
                     /locus_tag="VYO94_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV1759741.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
BASE COUNT         9272 a         6796 c         5623 g         9072 t
ORIGIN      
        1 tttaaaatgc cttttattac atgctgtttt atcaataaag tcggaaattc cacaaccttt
       61 ttgacaagac aattagtttc ttttgtatta taataattaa aattatctat atgcaactaa
      121 gattcggtaa ctatgctaaa caaatacatt gaaaaaagaa ttacagataa aattaccatt
      181 ttaaatatat tattggatat tcggtctatt gaactagatg aactgtctac tttaacttca
      241 ttacaatcta aaagtctcct aagcattttg caggaattac aagaaacatt cgaggaagag
      301 ttgacattta atttagatac gcaacaagtt caattaatcg aacaccattc tcatcaaacg
      361 aattattact tccatcagct ttataaccaa tcaactattt taaaaatact ccgcttcttt
      421 ctactacaag gtaatcaaag ctttaacgaa tttacacaaa aagagtatat ttccatcgca
      481 acaggctacc gcgtacgaca aaagtgtggc ttgttactac gttcagtagg tttggacctt
      541 gtgaaaaatc aagtagttgg tcctgaatat cgcattcgtt ttttaattgc actcctccag
      601 tttcattttg gtattgagat ttatgatttg aatgatggaa gtatggattg ggtcacacat
      661 atgattgtgc agtctaattc tcaactcagt catgaactgt tagaaatcac acctgacgag
      721 tatgttcatt ttagcatact agtggcactc acttggaaac gtcgggaatt tccacttgag
      781 ttccctgagt ccaaagagtt tgaaaaatta aaaaacctct ttatgtatcc gattttgatg
      841 gaacattgcc aaacttactt agagccacat gccaacatga cttttactca ggaagaactg
      901 gattatatct ttttggttta ttgttctgct aattcttcgt tttccaagga caaatggaat
      961 caagaaaaaa agactcatac tattcaactg attcttcagc atacaagagg aaagcatcta
     1021 ctatccaagt tcaagaatat cttaggaaat gacatttcga attctctttc ttttttaaca
     1081 gcactgactt tcttaacaag aacgtttttg tttggtttac aaaatctagt tccctattat
     1141 aattattacg aacattatgg gattgaaagc gacaagccac tgtatcatat ttcgaaagca
     1201 attgttcaag agtggatgac tgagcagaag attgaaggag ttatcgacca gcatcggctg
     1261 taccttttct cactctactt gacagaaacc atcttttcct cactacctgc tatcccgatt
     1321 tttatcattt taaataatca agcagatgta aacttaataa agtccattat tttacggaat
     1381 tttactgaca aagttgcctc tgttacagga tacaatattc taattagtcc tcctccttca
     1441 gaggagcatt tgacagagcc attgattatt attacaacga aagaatacct gccttacgtt
     1501 aaaaagcagt atcccaaagg gaaacatcac tttttgacga ttgccttaga tttgcatgtt
     1561 agccaacagc gtctcatcta tcagacaatt gtagatatcc gaaaagaggc ttttgacaaa
     1621 cgggtcgcaa tgattgctaa aaaggctcac tatttgttat aagttcatcg tactgtctac
     1681 acacaaaaag gggcttccta agccatctct attcttatcc ccatatttcc cagttttggg
     1741 taaatctgaa cagaaaaaca cttctgctct ctagtttctg ctagtgaaca aaagtgtttt
     1801 ttctggctct ataatttctg tagtgggtaa atcccactgt ggagattata gggctttttg
     1861 agtatcaaaa aagtcccata agacttataa tgaaaagcgc ctaaacaact cattagaaag
     1921 tatcttatgg aacacatcaa tcataccaca ttactcatcg gaataaaaga caaaaacatc
     1981 accttaaata aagccattca gcacgatacc catatcgaag tcttcgctac acttgattat
     2041 cacccaccta aatgtaaaca ctgtaaagga aaacaaatca aatacgactt ccaaaagcct
     2101 tctaaaatcc cttttatcga gattggtggt ttccctagcc tcattcattt gaaaaagaga
     2161 cgatttcaat gcaagtcctg tcggaaagtc actgtagctg aaacaactct cgttcagaaa
     2221 aattgccaaa tctcggaaat ggtgagacag aaaattgccc aactcctact caacagagag
     2281 gctcttacac atatcgcttc taaattagcc atctctacct ctacctctac cgtctatcgt
     2341 aagctcaagc aatttcattt ccaagaggat tacaccactt tgcctgaaat cctctcctgg
     2401 gatgaattct cctaccagaa ggggaaattg gctttcattg ctcaggattt caacactaag
     2461 aaaatcatga ccattcttga taacagacgt caaacaacca tccgaaatca tttcttcaag
     2521 tactcgaaag aagctagaaa aaaagttaaa gtcgtcactg ttgatatgtc tggaagttat
     2581 atccctctca ttaagaaatt atttcccaat gctaaaattg ttctcgatcg tttccacatt
     2641 gtccaacaca tgagcagggc tcttaatcag actagaatca acatcatgaa gcaatttgat
     2701 gataaatctc tggaatacag agctcttaaa tattactgga aatttatcct aaaagatagt
     2761 cggaaactct ctcttaagcc tttctatgct agaactttca gagagacctt aactcctagg
     2821 gagtgtctga agaaaatctt tactctagta cctgaactta aagattacta tgacctgtat
     2881 caactactcc tatttcatct acaagagaag aatactgacc agttttgggg cttaattcaa
     2941 gacacgttac ctcatctcaa ccgcaccttt aaaaccactt tgagcacatt tatttgctat
     3001 aaaaactaca tcactaacgc cattgaattg ccttattcta acgctaaact tgaggccact
     3061 aacaaactca tcaaagacat caagcgcaat gcctttggtt ttcggaactt tgaaaacttc
     3121 aaaaaacgga ttttcatcgc tctgaacatc aaaaaagaaa ggacaaaatt tgtcctttct
     3181 cgagcttagc ttttcttcaa cccactacag ttgacaaaga gcccttttta ttattcaaga
     3241 acttgattag ctcaatgcat ccaaggcgtc atccattgaa agaacttcgt ggaagacacg
     3301 ttgtgtcaat tcagtttttt gttctggagt gaggtattta gtgtttacac agtatccaga
     3361 gatacgtacg ataacgtctt cgcctgacat gattttttcg taaacatcgt tcaagtccat
     3421 aacgttcaag ttaacgtgtt gtccaccgtt ttcgaagtaa ccatcaagga ttgttaccaa
     3481 gttatcaact tgttcatcac gagtcttacc aagagcgcga ggtgatactt gtgtagtcaa
     3541 tgagataccg tcagctgcat aactaaagtc aaggctagaa agtgagttca agttttgcaa
     3601 ccaaccacct ttagctttgt tagatgggtt agcacctggt gagaagaatt caagtttaga
     3661 caagttcaca gaaccatctt cgttgaggta tacacctttg tgaactggtg agttaccagt
     3721 ttgtttagag taagcaacgt tagatgtgat tgtcaaaagt gatactgtag cttctgcgtc
     3781 tttgtatagt ttgtggctac gtagacgagt tgtgtaggct tcgatcaacc attctgccaa
     3841 ttcgtttgaa cgtgggtcat cttcacccca gcgtgggtag tcaccgattg tttcgtaatc
     3901 gtagatgtag ccatcttcgt cacggattgg tttaactgta gcgtatttga tagctgacaa
     3961 tgtatcaaca gtgttagcaa atccacagat accgaatccc atgttggcac gttgtttagt
     4021 tggcaagaag gccatttgaa cagcttcgta gttgtaccta tcagtcatgt agtggatgat
     4081 gttcaaggca tctacgtaag tgtcagtcaa ccagtcaaga gatttttcaa agttcgcttt
     4141 aactgattcg aattcaagaa cttcgtcacg gattggttcg atatcaaata ctttgtagtc
     4201 tttgtgaaca tcgtcgtaac caccattcaa accagtaaga agggctttaa gaacgtttac
     4261 acgagcaccg aagtactgga tgttgtggcg ttgttcttca ttttctggat caagtggaga
     4321 cacacagcat gagatacagc tcatttcacc atatccgtct ttagccattg ttgttacacc
     4381 ttcgtattgg atagaagagt gtttgtggct catgtgcata cagtagcgac ggaagttgta
     4441 tggcaatttg tcagtccaaa gaactgtcaa gtttggttct ggtgagttac cgatgttgtc
     4501 aagagtgttc aagaaacggt agtccatctt agtaacacgg tgacgaccgt cgttacccat
     4561 accagccata gaagttgtga taaaggttgg gtcacctgag tacaattggt cataagcttt
     4621 tgtacgagca aatttaactg tacgaagttt cataacgaaa tcatcaacga attcttggat
     4681 ttctgattca gtaaatgtac cacgagcaag gtcacgttct gcaaagatgt ccaatacgat
     4741 tggtacacga cctagagatg tagcagcacc gttaatcaca cggcagacag ccatgaaagc
     4801 aatgttaacc cattggattg cttctttcac gttcatcgct ggtttgcgaa catcaacccc
     4861 gtaaaggtca cccaggcgaa caacttgttg caatgcttgg tattgaaggt ttacttcttc
     4921 acgaagacgg attgtttctt catcgatttc tttgattgca ttccagtcgt ttactttttc
     4981 ttgcatcaag tagtctgcac cgtaaagagc aagacgtgcg taaacaccga tgatacgtcc
     5041 gcgtgagtat gcatctggaa gaccagttac agtgtgtgcg tgacgagcgc gacgaatatt
     5101 tgaagtgtag gcacggaaaa taccgtcgtt aactgttgtt acatatttag tgaagatttc
     5161 gtgaacagct gggtctggtt cgtatccatt ttcttttaaa gtagtttcag ccatacggat
     5221 accacctttt ggcatgaagt tcaatttgaa gagttcatca ttttggatac caaagataac
     5281 ttcattttct ttgtcgataa atccagcagg gatatcagcg atagatgttg gacgagtgtc
     5341 cattgggaaa cgagtttctt cgtagtgtgc tttagtttct tctacaattt tcttgatgtg
     5401 aagtgaacgc tctgttggtc ctgcaaggaa gctttcgtct ccatcataag gtgtgtagtt
     5461 agcttgtaca aagcgtgata cacttgcttt ttctttccaa tctacgcctt tgaagccttc
     5521 ccaagctttg tcaaaaatat cttgtgcttc aacaactgtc ttaacaacca tattaatgtc
     5581 ctcttttttc tagtaacagt catctgttac attcataaga caagtatacc ataaagtaac
     5641 cgatttcaac aagtgcaaaa tccctatttt tacactttct tttctaaaac agtctatatt
     5701 ttatttcaaa ctgtattata tttttgaaaa aaataaagtc cttttttctt tttttcagaa
     5761 aaaagggtat aataaaagaa aataagcagt aacactcaat ggaaatcgaa aagcaaacta
     5821 ggaagctagc cgcaggctgc tcaaagcact gctttgaggt tgtaaataga actgacgaag
     5881 tcagctcaaa atactgtttt gaggttgcag atggaagctg acgtggtttg aagagatttt
     5941 tgaaaagtat aaaaaggtgc taggcatgtt gatttttcct ttgttaaatg atttgtcaag
     6001 aaaaatcatc catattgaca tggatgcctt ttttgctgcg gtggaaatca aggataatcc
     6061 taaactcaga ggaaaacctg tcattattgg aagcgaccct cgacaaacag gtgggcgggg
     6121 agtcgtttct acctgtagct atgaggctcg agcttttggt gtccattctg ccatgagttc
     6181 caaggaagct tatgaacgtt gtccccaggc cgtctttatc tcaggaaatt atgagaaata
     6241 caaagctgtg ggactccaga ttcgagctat ttttaagcgc tatacagatt tgattgaacc
     6301 catgagtatt gacgaagcct atttggatgt gacagaaaat aaactcggta tcaagtcagc
     6361 ggtcaaaatt gctcgcctca ttcaaaaaga tatctggcaa gaactccatc taactgcttc
     6421 tgccggtatt tcctataaca agttcttagc taaaatggcg agtgattatc aaaaacctca
     6481 tggtttgaca gtgattctac ctgaacaggc tgaggatttt ctcaaacaaa tggatatttc
     6541 caaatttcat ggagtaggaa aaaagacagt agaacgtctt catcaaatgg gcgtttttac
     6601 tggtgctgat ttacttgaag ttcctgaggt gaccctaata gaccgttttg gtagactagg
     6661 ctatgatctg tatcgaaagg ctcgtggcat tcacaactct ccagtcaaat ccaatcgcat
     6721 ccgtaaatca atcggcaagg agaaaaccta cgggaagatt ctccgtgctg aggaagatat
     6781 caaaaaagag ctgactcttc tatcagaaaa agtcgctctc aatctacatc aacaagaaaa
     6841 agctggaaaa attgtcattt tgaaaatccg ctacgaggac ttttcaactc ttaccaaacg
     6901 aaaaagtatt gctcaaaaaa cacaagatgc tagtcagata agccaaatag ccctgcaact
     6961 ctatgaagaa ttaagcgaga aagaaagagg tgtccgccta ttggggatta ccatgactgg
     7021 attttaaagc tcaatgaaaa tcaaagagca aactaggagg ctagccgcag gctgctcaaa
     7081 acactgtttt gaggttgcag ataaagctga cgcggtttga agagattttc taagagtata
     7141 aaaccttgaa gagttgcccc ttcaaggttt ttcttataca aataaacgga caaaactgta
     7201 aagtagcaaa acactaccaa gcacgatacg gtatttacca aaaagggtga agtcgtgttt
     7261 tttcacatag ctggtcaaga agcgaatagc caccatgctg accgcaaaag ctactcccat
     7321 cgcgaccaag agcaaaaaca attgcccaaa gctcaagagt tctccggctt tcacaaattt
     7381 gaaaatcttt aaggcactag ctccaaacat aacgggaatc ccaagataga aggtaaattc
     7441 tgtcacaact gaacgactgg ttccatttaa caaaccaccg acaatcgttg cacctgaacg
     7501 gctagtccct ggtaaaagag caagaacttg gaagagtccg atatagaaag cggtcgtata
     7561 aggaagcttg tccaactctg ttacacttgg ctcgatagca cgcgctttat tgcgcttttc
     7621 caaatagatg aaggcaaccc cgtagataat caacatgaga gcaactgaaa ccatgttatg
     7681 gaagtgggta tcaaaccaat catcaaattt aaagacacca agtaaaggca aagtggcaat
     7741 caagaccttc aaccatagtc tccaagtctt acgaacttcc tgtttgtcct tagtcggttt
     7801 aaaaggattg agcttgttaa aataaatcac cataactgct aaaatagcac caagctgaat
     7861 cacgacatta aacatggaca taaaggcttc attttgattt tggtattgga taaactcctc
     7921 tgctaaaatc aagtgacctg tactggaaat cggcaaccat tccgtaattc cttcaacaat
     7981 cccgaagaag atagatttta aaatttcaat aagatacata tatttctcct tatattatat
     8041 ttaacgcagt tagctactgc caaagcccaa gtggtatact tggaataagc cactgtggat
     8101 tagttcattt cctccaatcg cttgacgatt tccgaaaggc tctaaccaca gctttttgtt
     8161 tcaattggta atgagtttga taacgcatag acgttttatc tcgtctaagg taacaaggca
     8221 aaaagttcgt ggataaccaa gtagacttga aatactacat ctggaggtac tcccatgcct
     8281 tatgtgggca ttgatgtcgc taaaaataaa cacgatgtta cagccttgaa tgttcaagga
     8341 aaaactgttc ttaaaccact cactttttca aataataaag ctggttttga actcttagat
     8401 ctgtctcttc gacagctcaa ccaagactgt ctcatcgctc ttgaagatac tggacattat
     8461 gcctttaatc tactgaactt cctgcatgaa caaggatata aagtttacac ctacaatcct
     8521 ttgctcatca agaaatttgc caaatcatta tcacttcgca agactaaaac ggataagaaa
     8581 gacgctcatg gcatcgctct taaacttctt tctgacccca atcgtgaaca atttcaacac
     8641 aataatcggc aagtagaact aaaaatactg actagacata ttcatcgtct caagaaaaaa
     8701 cagtctgatt ggaaagtaca atacactcgt tgccttgata tcatctttcc tgagttggat
     8761 aaaatcgttg gaaagcattc agaatatacc taccaactct tgacacgcta ccctaatcct
     8821 cagaaaagga ttgaggcagg atttgataag ctgatagaaa ttaagcgatt gaccgcttct
     8881 aaaattcagg atatcctctc agtcgcacct cgttctatcg gaacaacatc tcctgctcgt
     8941 gaattcgaaa tcatcgaaaa catcaaacat tacaagaggc tcattgacaa ggcggaaaaa
     9001 tgtgtcaatg acttgatggc tgagttaaac tcggtcatca cgacggttac tgggattggg
     9061 aatcgtttag gggcggtcat tttagccgag attcaaaata ttcatgcctt tgataatcct
     9121 gctcaattac aagctttcgc tggactggat tcttctattt atcagtcagg tcagattgat
     9181 ttagctggaa gaatgatcaa acggggttcc cctcatctgc ggtaggcact catacaagct
     9241 gccaaagcat gcgctcgctt ttcacctgct tttaaggcct atcttaagac taagttagaa
     9301 taaggaaaac attacaatgt agccatcatc caccttgcaa aaaaacttat ccgaaccctg
     9361 ttttatatcc taaaaaagag ctgccatttg acgaacaaaa agtgatgtaa tttctgaaat
     9421 caacacagga ttacctttga aaaaatggac tttttcaagg gctttttgcc gtgctctaaa
     9481 atcatcgcca aatcatcaaa ttgaactaag aaatagttta gataaaacta ttgacttttc
     9541 ttatagtttg tcttttttct atcttccatt atatcatact ttttcagtct atggtagctc
     9601 tctttaaaag gcaccgatac tgccgccacc tccgcctcca gagaagccac caccagaact
     9661 tccacttcca gaagatacag agtaggtgct tgctgtattt gcgacactag cataatggct
     9721 catttgtgct gttgaatgat aaaacatact gtgccagcca taagctacat agaaattgat
     9781 atctggattt tccacttgaa tctgatgaac cttcatcaaa tgactaacct tgtccgcata
     9841 gccaaataag gtcgcataga ccaagaggcg attccagacc acaatacttt ccagttcagc
     9901 ctgatccaat cgtgcaatct cacgcaacat attttcaaaa ctggtccaga gatagtagac
     9961 ctcagctccc gcttcattta gaacaccatc acgattatct agttgaagct tccaataata
    10021 gaaaacagac aaaactaacc ctagaaaacc aagtattggc aaggggaggt aaagatagcc
    10081 atgaacgtct aaactgtaca agaacaaacc aaatccgata aataggggca agatagtcaa
    10141 gacacccata cccacttgca aagccttttc caaaccagtt aaaggacgat agtaatctgg
    10201 gagtccccag aagacaactc gctttctcac tccttcttgc atctggttca atacctcttc
    10261 aaaagaagat ttgagctgaa tccctcttgc ttgaatccgt ttctcatcag cagctttagc
    10321 tctacgataa agactatcag ataccttgta atccgcaaac aaattggaaa gagtggcttc
    10381 ttttttacct gaaaaagcta gatttaggca gtctttctca aagcttgaca aaccatcttc
    10441 ttttactagc ctcaaaccaa ctgcatctcc ttctgaaatg atagagacat tcccacggtc
    10501 tatcacatct agcaaggtag cttgaataag ttgatcaaag gtgaattttc cagctccctt
    10561 gaccaaggga ctcacttcct ccaaggaggt cgagtagact gcttctgata aaaccatagg
    10621 ctctaattcc attgggggtt catagagacg atgattttta gcatatttga ttgaaggagc
    10681 ggtctttctt ctatagataa aatagaaaca gatgctcaat aacaaggaga tggaaaggat
    10741 cgaagggaag atccaagtaa gtagttgttt actttgctct ttttctttaa cgatcgaatc
    10801 ctctatctta ttaaactctt ctaaacgatt ccctttcaag ccctgatccc tagcgctagc
    10861 aaaatcagtt cgcggccagt aggcatgcaa ctcaactcca cgcttagccg gaagattgtc
    10921 taaacggata gtataatcaa ggttactctt ttcaatcgtt ccctctctaa aaagtttccc
    10981 tgtatggaaa aagagttttt cagccccctt gtctcccctt acatgaaatt caaacttttc
    11041 aatagactct gaactatctg tcagaggttg ccaatttaat tcagcgatat catcataaag
    11101 gaaaagtaaa ttttttaagt tccagacgag gtcaacttca actatgtcgc cctcctgacc
    11161 tggattatag actctcacag tataaccatc cgcttcttct gttacttcgc tagttacatc
    11221 tgctagttct gcaccgtttt tcgcggcctg aacctttgga tgagggtcaa tgtcaaaccc
    11281 gctaggcatc ttaccagcac gtccaagtcc cacgatttgt cccttaaagt cctcctcaaa
    11341 ctggtaaact atcttctgtc taaactctgc cgtattatct gcatgaatat acaaatcccc
    11401 ttgataagag tttatcttga aatcaatggc aaaaacagag agtggaagaa ggcaaaacaa
    11461 gcctaacacc agtaagaaaa aagttttttt catcaactaa gccccctttt tatctttctt
    11521 atcattatag cattttttcg taagtaaagg cttacttatg ttgaaaaatt acgcattttt
    11581 cgataaaata ggagacagtt attttttaat agatcagaat aggagaaatc atgagaaaaa
    11641 tatacttatc tattttcaca agtctcttgc tgatgctagg acttgtcaat gttgctcaag
    11701 ccgatgaata tttacgcatc gggatggaag cagcatatgc tccctttaac tggacccagg
    11761 atgatgatag caacggagct gtcaaaatcg atgggaccaa tcagtatgcc aacggatacg
    11821 atgttcaaat cgccaagaaa atcgctaagg acttaggtaa agaacctttg gttgttaaaa
    11881 ccaagtggga aggtctagtc cctgccctta cttctggtaa gattgacatg attatcgcag
    11941 gtatgagtcc aactgcagaa cgcaaacaag aaattgcctt ttcgagcagt tactacacta
    12001 gcgaaccagt tttgcttgtc aaaaaagatt ctgcctacgc aagtgctaaa tctttggatg
    12061 actttaacgg tgcaaaaatc acttctcaac aaggggtcta cctctacgac ttgattgcac
    12121 aaatcccagg tgctaaaaaa gaaacagcca tgggagactt cgctcaaatg cgacaagctc
    12181 ttgaggctgg tgtcattgat gcttatgttt ctgaacgtcc agaagcactg actgctgaag
    12241 ctgcgaactc taagttcaag atgattcaag tagaacctgg tttcaaaact ggggaagaag
    12301 atacagctat cgctatcgag cttcgtaaaa atgacaatcg tattagccaa atcaatgcca
    12361 gcattgaaac catttcaaag gacgaccaag ttgccctgat ggatcgtatg atcaaggaac
    12421 aacctgccga agctacaaca actgaagaga ctagcagtag tttctttagc caagtcgcta
    12481 aaattctttc tgaaaactgg caacaactct tgcgtggtgc tggtatcact cttttaatct
    12541 ctatcgtcgg aaccatcata ggtctcatta ttggacttgc cattggtgtc ttccgtactg
    12601 ctcctctctc tgaaaacaaa gccatttatg gccttcaaaa actagtcggc tgggttctca
    12661 atgcctacat tgaaattttc cgtggtacgc caatgattgt tcaatcgatg gttatctact
    12721 atggaactgc ccaagctttc gggatcaacc ttgaccgtac actggctgct atcttcatcg
    12781 tttcaatcaa taccggtgcc tacatgactg aaatcgtccg tggtggtatc ctagcagttg
    12841 acaagggaca atttgaagct gcgactgctc ttggtatgac ccataaccag accatgcgta
    12901 agattgtcct acctcaggta gtccgtaaca tcctacctgc aactggtaat gaatttgtca
    12961 tcaatatcaa agatacatct gtattgaacg ttatctctgt tgtcgaactt tatttctcag
    13021 gaaataccgt ggcaacacaa acctatcaat acttccagac atttacaatc atcgccgtga
    13081 tttactttgt cctcaccttc accgtaacac gtatcctacg ctttatcgag cgcagaatgg
    13141 acatggatac ctacactaca ggtgctaacc aaatgcaaac ggaggatttg aaataatgac
    13201 acaagcaatc cttgaaatta aacacctcaa aaaatcctat ggacaaaacg aagtgctaaa
    13261 agacatttca ctcactgtcc acaagggaga ggtcatctct atcatcggaa gctctggaag
    13321 cggaaaatcg accttcctac gctccattaa cctacttgaa acaccaactg atggacaaat
    13381 cctttatcat ggacaaaacg tcctcgaaaa aggctatgac ctcacgcaat accgtgaaaa
    13441 gttggggatg gttttccaat cctttaacct ctttgaaaat ctcaatgttc ttgaaaacac
    13501 aatcgtcgct cagacaactg tcctaaaacg cgaacgcaca gaagctgaaa agattgccaa
    13561 agaaaacctg gaaaaggtcg gcatgggaga acgctactgg caagccaaac caaaacaact
    13621 ctcaggtggt caaaaacaac gtgtggccat cgctcgtgcc ctctccatga atccggacgc
    13681 tattctcttt gatgaaccaa catcagctct cgatccagaa atggttggag aagtcctcaa
    13741 aatcatgcag gacctggctc aggaaggctt gaccatgatt gtcgtaaccc atgaaatgga
    13801 atttgcccgt gatgtctctc accgtgttat ctttatggat aagggcgtga tcgctgaaga
    13861 aggtaaacca gaagacctct tcaccaatcc taaagaagac cgaacaaaag agttccttca
    13921 acgctatctc aaataaaaag aaaaggctgc atcaaccgtg cagtcttttt gctgtcctca
    13981 aaatgaaaag gcagattctc tatctctact acttgaaggt caagaatccg ccgttatcca
    14041 aagattaatc ttcaaatttt tcataatttt tttcatagaa atcaattagg cctagggctg
    14101 tttcaaatga aatatttttt acttttgcac gaccctgcgc cagagcaatg atagacattt
    14161 cacgcgcatt cgtttcttta gagatacggt agcctgtgat tttcttatca cgaacccagc
    14221 caacaactga ttctactttt tcaaagtttg acttagccat gtttttctcc tattttcttc
    14281 tttataatat ttaattgtat acgtttttac tacttttgtc aataaaaaaa acatatattc
    14341 aacgaaaata attagttcag aattttctta cttccttttt aaatccgata atatataggt
    14401 tttgctagcc tctacaccat aaatatttgc taataaaaat actgtattat taccctctta
    14461 aggtgcgaaa ttattcaagt tcttaaaaaa tgcttctcta tttccgtaag atagcttatt
    14521 tcttcgattt aagaactgaa gatgatagtt ctaaccttta gaaatccaag ccttcactag
    14581 ctcaaaaact cctatctttc ttcctcaata aatcatctga gagataggta ttccttatgt
    14641 ccttcaaatt catcactcct ttggatattg aggtgctagc ctagaagcag acacccgatt
    14701 atctaaacca tccttaataa agatgacaag acagataagc tcagttaatt acttatatat
    14761 ctttttaata tggtatattt gtcaacaaaa agaaatcaaa tcatacctta tactcaatga
    14821 aaatcaaaga gcaaactagg aagctagccg caagttgctc aaaacactgt tttgaggttg
    14881 cagatagagc taacgtggtt tgaagagatt ttcgaagagt attaaagaca gtgtgactat
    14941 gcttgtcaat agataggaaa tcaaaatgaa ggatggaaat ctgagccaaa catcataagt
    15001 gctataatga acagaagtaa gaattgcacg ataagttttc taaaaccata ggaatcgtcc
    15061 cctttcttca tcttcattat agcacatata catcagttgt acaaataata tgatattttt
    15121 ttattagtcc tcagacaagc atattataaa gcgtttcatt accatttaag ttaatataag
    15181 ctggatcaaa accttccatt ctacgaatca aacctgcata atcatgctta tctgctaaag
    15241 cgatcccaat taatactggg cctgttccct tgctagctcg tttgatatac tcaaaacgtg
    15301 tgatatcatc atttggcccc aggatatcat ttacaaactc acgcaaagct cctggacgtt
    15361 gtgggaaatt gaccacaaag taatgtttga taccatcata aatcaaggca cgctcttcca
    15421 tttctggcat acggttgata tcattatttc ctccagaaat gatacaacaa atggttttcc
    15481 ccttaatata ttcagctaaa acctctaaag aggcgatact agctgctcca gcaggttctg
    15541 cgactatccc ttgcttagag taaaggtcaa tcaaggtttc agaaatcaat ccctcatcga
    15601 cacctaccaa agtttgaata tgttgacgag ttgcttcata ggtcaactga cctacctttt
    15661 gcacagcaat cccatccgca aatttatcaa tttccttgag tttgactgga cctccagcct
    15721 caaaggcagc tttcatagaa cgcgctccat tcgcctctac tccgataacc tcaatctctg
    15781 gacttgtttc cttgatatag gtagaaaccc cggcaatgag accgccacca ccaacaggaa
    15841 ccaagacagc atcaaaatca atcgattctt ttcgagcttc ttctaaaatc tcataagcaa
    15901 ctgttccttg acctgcttga acatgagcat catcaaaagg atcaataaag gtacgatttt
    15961 cagagactgt aaattcttga gctgctttgg ctgaggcatc aaaggtatct ccaactagtt
    16021 taatagttac aaaatcccca ccaaaaaagc gaacctgacc aatcttttgt tgtggcgtag
    16081 taatgggcat aaagatagta gcaggaattt tcatttcatt acaagtatag gctactccct
    16141 gcgcatgatt tcccgcagaa gcgcagacta ccccacgttc acgttcttcc ttgctgagct
    16201 gggaaatggc ataataggca ccacgaattt taaaggagcg aacacgctgg gcattttctt
    16261 ttttcaaata aatcttagca ccatacttct ccgataaata atgatcgtaa tccagtggag
    16321 tattcacaac cacaccgttc aagaccttgt gagccttgat tatatctttt gaacttaaca
    16381 tataaaacct ctttttctat aaaaaacagt cactaatgac tgttttttag ttattcatct
    16441 ccgaaaactt cagtaacact ttcatggtat ttatgagcca tacgaatcga aaactcttta
    16501 ggaagttcat aacgatttgt ggaaatccaa tcatataacc attctaccaa actttcttca
    16561 ctatcattac gatggaagat aaaatagttt aaaatttctt tatattctac atcattcaaa
    16621 tccaacgtgt ctacaaattg actacgagga acaaaattag aatctaattt tcttagttga
    16681 tctgtcaatt ctcccaattg taaatccaac tgaaaaaata gtttttgcag ttgcctatca
    16741 gtttcatcac atcctgtctt gatagaaaac aaattggtaa tattcatatg atttcaaccc
    16801 ctaaataagt acatctaata tcccacgaat agctgaagct aaagttttcg cagtccagtc
    16861 atttaaaccc gattctttca atccagatgc aataatttgc tctatttgat ataaaccgcc
    16921 atctatcgtc tcatttattc tgcgaagagg accttcaata taggataaag cttctccgaa
    16981 tctaacagct gatttaggtc ctaatgattt accaactata tttgttaatg ttttttattt
    17041 ctcaaaatcc atttcgctat ataacgagca gatttagtcg caccagctct ctcaaacgga
    17101 gaatgaattt caagaccttc ttctctagct atttgtgcca atttgaagaa ttgttcaaag
    17161 gtcatatgca acctaccatc ttcaaaatta gcatcatcat aaatgttaat tacagcattt
    17221 tcatcatacg accaatctgc tttattttgg tctgctagca ctattaccga cggtgtaatt
    17281 acattataca actagaacca ataataacga tgcaattttt ctcataatct ttttcataaa
    17341 atcatctcca gcgctatata tttctaatta gttatagatt ttgaatgcat catcgtcgtt
    17401 tttaccaacg aatggcattg ctttacgcaa ttctgcacca actttttcaa tttcaaggtt
    17461 agctgcttgt tcacggtaag cagtcaattt tggacgtcca gctttatagt catttacaaa
    17521 gtcatttgca aatttaccat tttggatgtc tgccaagaca gccttcatat tttctttaac
    17581 ttgttcagtg attacacgtg gacctgatac atagtcaccg tattcagcag tgtttgaaat
    17641 agattgacgc attttcttga atccaccttc gtagatcaag tcaacgatca atttcatttc
    17701 gtgaagaact tcaaagtaag ccaattctgg agcgtaacct gcttctgtca agacttcgaa
    17761 acctgcttcg ataagggcag tcaaaccacc acaaagtaca gcttgttcac caaacaaatc
    17821 ttcttcagtt tcttctttgt aagttgtttc aagaagacct acacgagccg ctccaacacc
    17881 tttacaccag tccatagcaa tgtttttagc atttcctgtt gcatcttggt atactgcata
    17941 aagagctgga acaccaaatc cttcttcgta agtacgacgt accaagtgtc ctggtccttt
    18001 aggagcacac atgaagacat ctacatccgc aggaactttg ataaattcaa agtggatgtt
    18061 gaaaccatgg gcaaatccaa ctgcgtttcc agcttccaag tttggagcga tttctgcttc
    18121 gtacaattct tgttgaattt cgtctggcgc caagatcatg ataacatcag ccaacttagt
    18181 agcttctgct actatgtaag tatcaaatcc atcttctttt gctttatcaa aagatttacc
    18241 tggacgtaca ccgataataa cgtcacgacc tgaatcacgc aagttttgag catgcgcatg
    18301 cccttgtgaa ccataaccga taacggcgat ttttttaccg tcaagtgctg ctactttaac
    18361 atctttttca tattccattt gaactgtcat agcttttctc tcttttctat tatttattgc
    18421 cttttaggct ggtttaataa atttaagttg gatttttaat cgcgggtaaa tccagttgca
    18481 cccgttcgag caatattgcg aataccgtat gggcgaatga ctcgcaatag ggcttcgctc
    18541 ttttctgcat ttcccgtcat ctgaatggta atcgagcttg gcgctacgtc taccactgtt
    18601 gcacggaaag gttgaataat cgctaaaatc tcagctctct tctcagctgg cgctgacatc
    18661 ttaaccaaaa tcacctcgcg ctccaaatga ggcttgtctg taatatctcg aatgcgaatc
    18721 acatcaatct gacgattgag ctgtttgatg atttgctcca cttcatcatg agaagcaaca
    18781 tcaataataa tagtgatacg cgatacattc ggatcttctg ttgctccaac agagatgctt
    18841 tcaatattaa cctgacgacg agataggaca cctgtaaagc gattgaggac tcctgaacga
    18901 ttttgtagtt ttgctgttaa cattctacgc atggaactgc acccccaaca tctcatgatt
    18961 actcttacca gccggtacca ttggtaacac ctgttcctta cgagaaatat ctacctcaat
    19021 tagcatagga acatcctcag tgatgacttc aaggtcttga gccaaggtct caggattgtc
    19081 aaacttatag tttttaatac cataagcctg cgccatcaat tggaaatcag gaagggtatc
    19141 aaagaccgac tctgatgttc tgccttcata gaaggattcc tgccactggc gaaccattcc
    19201 aagtgaatga ttgttcagca taaccacctt gattggcacc ttgtaaatat tcaaaatagc
    19261 caactcctgg ttggtcattt ggaaaccacc atccccaaca aacaagacta cttccttatc
    19321 tgggttagca attttagcac cgattgctgc tggaattcca aatcccattg ttcccaaacc
    19381 acctgaagtc actaactgac gttcattttg gtagggataa tactgagctg tccacatttg
    19441 gtgttgacca acgtctgtta ccacaatggc atctccattc gtcaattcac caattcgttc
    19501 aataactgct tgcggttgaa ccacacgctc tttcttgtca taagaacgaa cacgattctt
    19561 gtctttagtg actttctcaa tccacttttc agtattgttg tgaactgttg gttctgctag
    19621 caacatttgc aaggccttct tagcatctcc aactacagga atgtctgcac tgataatctt
    19681 gccaatctca gctgggtcaa tatcaatgtg ggcaacctta gcattcttag cgaaagtctt
    19741 aggattcccc gtcaaacggt catcgaaacg agaaccaata ctaatcataa agtccgcttc
    19801 cgtcatggca atatttgctg cgaatgaccc gtgcatgcct cccattccaa gaaagagtgg
    19861 gtgactcgtt gcaatcgttc cttgtcccaa aagactggtt accactggaa tttgatagcg
    19921 ttctgcaaat tcatttagtt ccgtagcagc ctcagcataa ctaattccac caccagctaa
    19981 caagactggc tttttagcct tggacaattg cttcaagatt ttcttgattt gcatatcatt
    20041 cggctcaaga gtcggctgat aacttggtaa attcacttct ggtgaataaa tgaagtctgt
    20101 ttctaaagca gatatgtctt ttggtaggtc aattacaact ggccctggac ggcctgtagt
    20161 tgcgatatgg acagcttccg taatgatacg cggaatatca gctgtctcac gaacttggta
    20221 attgtactta gtgattggca tggtaattcc tacgatgtct gcctcctgaa aggcatcctt
    20281 cccaatccct gctcgcgcca cctgacctgt aaagaccaaa aggggaacgc tatcgctcat
    20341 agcatccgca atccctgtaa tggcatttgt tgctcctggt ccactagtga cgacggcaac
    20401 acccaacttt ccagttgatt tggcataacc ttcagcttca tgcaaacaac cttgctcatg
    20461 gcgccctaga atgtggcgaa tgcctttaaa attatatatc gcatcataaa aaggcaaaac
    20521 cgcaccacca ggataaccaa agatggtatc aactcctaaa tcacgaagtg tttccaaaac
    20581 taggtccgac cccgtcttag gagattctaa actgattttc tccattgttc ccctttcttt
    20641 cctcttaaaa ataacttgtt actatcatac cattttttca aaatttttca agataaaaga
    20701 agaaattttc tgaattttct attttaacgt ttatttatga atgttatttt tgtttttatt
    20761 aaaaagatac cgatttcatt tactaaaaaa gaaaaaagaa ctgatttctc agtccttcat
    20821 taatcttatt ccacactaaa taggtatggg taaacaggtt gttgaccttg gtgaatctcg
    20881 acttcaacgt cttcgaattc ttctacgatt tcttgagcga tttcattggc aagttcttcg
    20941 cttccgtctt caccgacata gaaggttacg atttcactgt cttcatccaa catatgtttc
    21001 aaggtttcag tcaatgtttg gtgcatatca gggtttgaca caagaatttt tccatccacc
    21061 atacctagat tatcgttttc atggatttct aagccatcga tcgttgtatc acgcacggct
    21121 gttgtgacgc ttccgctaac gacatcgcta agagcagctg tcatacgctc ttggttttct
    21181 tcaatggact tgcttggatc aaaggcaaga agacttgtca taccttgagg aagagtgcga
    21241 gcctctacca ctactgctgg ttgctccaaa acttctgccg cagattgagc tgccatgaag
    21301 atgttcttgt tatttggcaa gaagatgatg ttacgggcat tgacctgttc aacagccttg
    21361 ataaagtctt ctgttgaagg gttcatggtt tgaccgcctt cgataacata gtccacgcct
    21421 tgagaacaga agatatctgc tagaccttta ccagccacca cagcaattaa agcatactct
    21481 ttttcttcag ccgacttgat aacttgagta gcttctttct caacctgtgc ttcgtgttgg
    21541 ttacgcatat tgtcaacttt taccttgacc aagctaccat atttgagacc ttcttgcata
    21601 acaagtcctg gatcttctgt atgaacatgg actttgacaa tttcatcatc gttaacaacg
    21661 aggagagaat ccccaagctc atccaagtag ttacggaatt catcgtagtc aaaatcttta
    21721 gcataggttg gaccttgctt aagagctacc atgatttcag tacagtaacc aaacgtgatg
    21781 tcctcagtcg ctacgtgacc agctacagac ttatgatgct ctacattgat catctcactc
    21841 atgttggcag gagtcgctac aaagtcctca gatgcaatat attcgccagt aagggctgaa
    21901 aggaaacctt cgtagatgaa gaccaatcct tgaccacctg agtccacaac gccaacttct
    21961 ttcaatactg gaagcatgtc tggtgtttta gctagagctg ttttagcacc ttccaaggct
    22021 gcgcgcatga cttcaacagt gtcatctgtt tgctcagctt ttttcttagc accgatagca
    22081 gctccacgag aaactgtcaa aatcgttcct tcaacaggtt tcatcactgc cttataggca
    22141 acttccacac ctgattggaa ggccagagcc aagtcttgac ctgttaactc gtctttatcc
    22201 ttgatagctt gggaaaatcc acggaaaagc tgagacgtaa tcactcctga gttcccacgc
    22261 gcacccatca aaagcccttt ggcaagaatg ctcgctactt ctccaactgt agaagctggc
    22321 ttgtctgcaa cttctttagc accattttca atggtcattc ccatatttgt cccagtatct
    22381 ccatctggaa ctggaaagac gtttaatgaa ttgacatatt cagcttgctt attcaagcga
    22441 gttgatgcag cctgcaccat ttcttgaaat aagctagtag taatttttga cacggttatt
    22501 ctcctacaac tttgatattt tgaatgtaga catttacagt ctgagcagta attccaagct
    22561 ggttttccaa gctaaaggca acacgctctt gaatgttttt tgacacttca ctaatctttg
    22621 ttccgtagct taacacggta tatacatcaa ctgcaatact gccatcttcg gctgccttta
    22681 cgacgacacc tttagaataa ttttccttac ctagcagggc ttggaaatta tctttgaggg
    22741 catttttact agccataccg accacaccaa aaatctcagt tgctgctcca cctacgacgg
    22801 ttgcaatcac ttcatctgtt agttcgattt gaccatcttt tgtattaatt tttacagtca
    22861 tcctttttac ctcaactagt tgatactcta ttttatcata tttcagccca agtgtaaaag
    22921 cagaatgatg tatcagcgga tatttactct atttttcaaa cgatgttata cccacaataa
    22981 aagaaaaaag accctaaggt ctcctttgct tttattatta aacgcgttca actttacctg
    23041 atttcaaagc acgagctgaa gcccaaactt ttttaggttt accatcgata agaacagtaa
    23101 ctttttgaag gtttggtttt acggcacgtt ttgtttggtt catcgcgtgt gaacggttgt
    23161 ttcctgatac agtcttacga cctgtaaagt aacatacttt agccattgtg ttttcctcct
    23221 attagatcta atatagcgga tgtgctagca ccacataccg tactatgtta tcacactttc
    23281 ttgttttttg caagggaatt ggaagatttt ttatttgtgt cttaaatcag gtcttgcgtg
    23341 acattttctg ctctccacat gccattgttg attaacagaa caccagaatt aaaattatgt
    23401 gtataaaaat catctctaac tgcagctaag ggtatagccg tcaagtccaa atcccacagc
    23461 tcatctatcg attttcttac aacaatatct gaatccaaat acagtacacg agactcgctt
    23521 acatactttg gaataaaata cctaaaaaaa gccgcatatg aaagtccctc aaaggggaga
    23581 cgataacctt tcagaatact actgtcaatc tgaacattca caatctcact attcaaagtc
    23641 tctagtcttt tttccatcaa ttggaaccat tctcgcggaa ggtcatcatt aaaaacataa
    23701 aacttaagat tataatgatg aacacaaaga gattttattg ttgtttcaac tttatccata
    23761 taagcattat ctgcacctaa gacaatcgct tttttctctt ctttcactct ttatcttatt
    23821 tctttttatt cccatcatat tattcccatc atatgtttct acgtaaccat tattttcgcc
    23881 tattcgttcg taaaaccata ccagtggaga ttttagatga agtcccatta cggtttacaa
    23941 tttttacatt acgacacgga gttttacaaa tcgatttcat ttgccaaacg tagttagtaa
    24001 ggcagttagc taggctacct actttctgct acgacggaaa aatccacaaa tcaataccat
    24061 tcgtggattt ttcctagtga agcgtttagg taagccgcca tagcggttac cgattattat
    24121 attacgacac ggagtttggc aaatcgattc tatttgccaa acgtagttag tgaggcagtt
    24181 agctagttcg ccaaatagcg actagcgtcc aacaatttgg aactttagtt ccaattgttg
    24241 gtactgagtc acatcttctc ctctaactct acgtctggat acttgtccgc aaaccagcgg
    24301 agggcaaagt cattttcaaa gagaaagact ggttggtcaa aacggtcttt ggctaagata
    24361 ttgcgacttg acgacatccg ttcatccaag tcctcaggct tgatccaacg aacggtcttt
    24421 ttacccattg ggttcataac tacttctgca ttgtactcgc cttccatgcg gtgtttaaag
    24481 acttcaaact ggagttgacc tacagcgcct agcatgtact cacctgtttg gtaattctta
    24541 taaagctgaa cggctccttc ttgcaccaat tgctcaatcc ccttgtggaa ggatttttgc
    24601 ttcataacat tcttagcaga aactttcatg aaaatttcag gagtaaaggt tggcagtggt
    24661 tcaaattcaa acttgttttt accaactgtc aaggtatccc caacttgata agtaccggta
    24721 tcgtaaaccc cgataatatc acctgccacg gcattgatca cattctcacg actttccgcc
    24781 ataaactgag taacattaga cagtttagcc cccttaccag tacgagggag attgacactc
    24841 atgccgcgct caaattcgcc agatacgata cggacaaagg caatacggtc acggtgacga
    24901 gggtccatgt tggcttggat tttaaagaca aatcctgaga aatccttgtc ataaggatcc
    24961 acaatttcac cgtctgtttt cttgtgacca tgtggttctg gagcaaactt gaggaaggtt
    25021 tcaaggaagg tctgcacacc aaagtttgtc agggctgaac cgaaaaagac aggcgtcaat
    25081 tctccagcca gaatagcttc ctctgaaaac tcattcccgg cttcatttaa aagctcaatg
    25141 tcatccttga cttgctcgta gaaaggattg ctaccaaaga gtttgtcccc gtcttctaga
    25201 ctggcaaaac gctcatcccc tttgtaaagc tctaaacgtt ggttatagag gtcatacaag
    25261 ccctcaaagg ctttccccat cccgataggc cagttcatag ggtagctagc aatgcccaag
    25321 atttcttcca attcttgcaa gagatccaaa ggctcacgac cgtcacggtc cagcttgttc
    25381 ataaaggtaa agactggaat gccacgatgt ttcacaacct caaacaattt cttggtttga
    25441 gcctcgatcc ccttggcaga gtccacgacc atgaccgcag catccaccgc catcaaggta
    25501 cgataggtat cttctgagaa gtcctcgtgc cctggcgtgt ctaagatatt cacgcgcttg
    25561 ccgtcgtagt caaattgcat aacagatgaa gtaacagaaa tcccacgttg cttctcgata
    25621 tccatccagt cagatttagc aaaagtccct gttttcttcc cttttaccgt accagcctca
    25681 cgaatctcac ccccaaagta gagtaactgc tcagtgatgg ttgttttccc cgcgtccggg
    25741 tgggagataa tggcaaaggt acgacgtttc ttaatttctt cttgaatatt cataagttct
    25801 ctttctttga ttctctattt ttcttgtttc aatagctgag aatgattttt acattggatt
    25861 ttaccattcc tttcaacact ccattatatc ggattttagc atttttttca atttctattt
    25921 cttttcactt ccccctccct tatttatagg aaaatatggt aaaatagaac agactaaaaa
    25981 tcatcatttc acgaaaggat gcaagatgaa aattacgcaa gaagaggtaa cacacgttgc
    26041 caatctttca aaattaagat tctctgaaaa agaaactgct gcctttgcga ccaccttgtc
    26101 taagattgtt gacatggttg aattgctggg cgaagttgac acaactggtg tcgcacctac
    26161 tacgactatg gctgaccgca agactgtact ccgccctgat gtggccgaag aaggaacaga
    26221 ccgtgatcgc ttgtttaaaa acgtacctga aaaagacaac tactatatca aggtgccagc
    26281 tatcctagac gatggaggag atgcctaatg acttttaaca ataaaactat tgaagagttg
    26341 cacaatctcc ttgtctctaa ggaaatttct gcaacagaat tgacccaagc aacacttgaa
    26401 aatatcaagt ctcgtgagga agccctcaat tcatttgtca ccatcgctga ggagcaagct
    26461 cttgttcaag ctaaagccat tgatgaagct ggaattgatg ctgacaatgt cctttcagga
    26521 attccacttg ctgttaagga taacatctct acagacggta ttctcacaac tgctgcctca
    26581 aaaatgctct acaactatga gccaatcttt gatgcgacag ctgttgccaa tgcaaaaacc
    26641 aagggcatga ttgtcgttgg aaagaccaac atggacgaat ttgctatggg tggttcaggt
    26701 gaaacttcac actacggagc aactaaaaac gcttgggacc acagcaaggt tcctggtggg
    26761 tcatcaagtg gttctgccgc agctgtagcc tcaggacaag ttcgcttgtc acttggttct
    26821 gatactggtg gttccatccg ccaacctgct gccttcaacg gaatcgttgg tctcaaacca
    26881 acctacggaa cagtttcacg tttcggtctc attgcctttg gtagctcatt agaccagatt
    26941 ggaccttttg ctcctactgt taaggaaaat gccctcttgc tcaacgctat tgccagcgaa
    27001 gatgctaaag actctacttc tgctcctgtc cgcatcgccg actttacttc aaaaatcggc
    27061 caagacatca agggtatgaa aatcgctttg cctaaggaat acctcggtga aggaattaac
    27121 ccagaggtta aggaaaccat tctaaatgcc gctaaacact ttgaaaaatt gggtgctatt
    27181 gtcgaagaag tcagccttcc tcactctaaa tacggagttg ccgtatacta catcatcgct
    27241 tcatcagaag cttcatcaaa cttgcaacgc ttcgacggta tccgttacgg ctatcgcgca
    27301 gaagatgcaa ccaaccttga tgaaatctat gtaaacagcc gaagccaagg ttttggtgaa
    27361 gaggtaaaac gtcgtatcat gctgggtact ttcagtcttt catcaggtta ctatgatgcc
    27421 tactacaaaa aggctggtca agtccgtacc ctcatcattc aagatttcga aaaagtcttc
    27481 gcggattacg atttgatttt gggtccaact gctccaagtg ttgcctatga cttggactca
    27541 ctcaaccatg acccagttgc catgtacttg gctgacctct tgaccatacc tgtaaactta
    27601 gcaggactgc ctggaatttc gattcctgct ggattctctc aaggtctacc tgtcggactc
    27661 caattgattg gtcccaagta ctctgaggaa accatttacc aagttgctgc tgcttttgaa
    27721 gcaacaacag actaccacaa acaacaaccc gtgatttttg gaggtgacaa ctaatgaact
    27781 ttgaaacagt catcggactt gaagtccacg tagagctcaa caccaattca aaaatcttct
    27841 cacctacttc tgcccacttt ggaaatgacc aaaatgccaa cactaacgtg attgactggt
    27901 ctttcccagg agttctacca gttctcaata aaggggttgt tgatgccggt atcaaggctg
    27961 ctcttgccct caacatggac atccacaaaa agatgcactt tgaccgcaag aactacttct
    28021 atcctgataa ccccaaagcc taccaaattt ctcagtttga tgagccaatc ggttataacg
    28081 gctggattga agtcgagcta gaagacggta cgaccaagaa aatcggtatc gaacgtgccc
    28141 acctagagga agacgctggt aaaaacaccc atggtacaga tggctactct tatgttgacc
    28201 tcaaccgcca aggggttccc ttgattgaga ttgtatctga ggcagatatg cgttctcctg
    28261 aagaagccta tgcttatctg acagccctca aggaagttat ccagtacgct ggcatttctg
    28321 acgttaagat ggaggaaggt tcgatgcgtg tggatgccaa catctccctt cgtccttatg
    28381 gtcaagagaa attcggtacc aagactgaat tgaagaacct caactccttc tcaaacgttc
    28441 gcaaggggct tgaatacgaa gtccaacgtc aagctgaaat acttcgctca ggtggtcaaa
    28501 tccgccaaga aacacgccgt tacgatgaag ctaacaaagc aaccatcctc atgcgtgtca
    28561 aggaaggggc tgctgactac cgctacttcc cagaaccaga cctgcctctc tttgaaatct
    28621 caaacgagtg gattgaggaa atgcggactg agttgccaga gtttccaaaa gaacgtcgtg
    28681 cgcgttatgt atctgacctt ggtttatcag actacgatgc tagtcagttg actgctaata
    28741 aagtcacttc tgacttcttt gaaaaagctg ttgccctagg tggtgatgcc aaacaagtct
    28801 ctaactggct ccaaggggaa gtcgctcagt tcttgaatgc tgaaggtaaa acactggaac
    28861 aaatcgaatt gacaccagaa aacttggttg aaatgattgc catcatcgaa gacggtacta
    28921 tttcatctaa gattgccaag aaagtctttg tccatctagc taaaaatggc ggtggcgcgc
    28981 gtgaatacgt ggaaaaagca ggtatggttc aaatttcaga tccagctatc ttgatcccaa
    29041 tcatccacca agtctttgcc gataacgaag ctgctgttgc cgacttcaag tcaggcaaac
    29101 gtaacgccga caaggccttt acaggattcc ttatgaaggc aaccaaaggc caagccaacc
    29161 cacaagttgc ccttaaacta cttgcacagg aattggcgaa gttgaaagaa aactagacag
    29221 aacaaaacca gccctaaggt tggttttttc ttctctacca actcccaata actattttgg
    29281 ctttatttcc agagtatttt atggtaaaat gaagagtaat aatatttatt aaagaggtaa
    29341 aaacatgatt gaagcaagta aattaaaagc tggtatgacc tttgaaacag ctgacggcaa
    29401 attgattcgc gttttggaag ctagtcacca caaaccaggt aaaggaaaca cgatcatgcg
    29461 tatgaaattg cgtgatgtcc gtactggttc tacatttgac acaagctacc gtccagagga
    29521 aaaatttgaa caagctatta tcgagactgt cccagctcaa tacttgtaca aaatggatga
    29581 cacagcatac ttcatgaata cagaaactta tgaccaatac gaaatccctg tagtcaatgt
    29641 tgaaaacgaa ttgctttaca tccttgaaaa ctctgatgtg aaaatccaat tctacggaac
    29701 tgaagtgatc ggtgtcaccg ttcctactac tgttgagttg acagttgctg aaactcaacc
    29761 atctatcaaa ggtgctactg ttacaggttc tggtaaacca gcaacgatgg aaactggact
    29821 tgtcgtaaac gttccagact tcatcgaagc aggacaaaaa ctcgttatca acactgcaga
    29881 aggaacttac gtttctcgtg cctaatctct agaaagaggt cattctatgg gaattgaaga
    29941 acaacttggc gaaatcgtta tcgccccacg tgtacttgaa aaaatcattg ctatcgctac
    30001 tgcaaaggta gagggtgttc actctttttc aaacagatca gtgtctgata ccctttcaaa
    30061 actttcactc ggccgtggca tttatcttaa aaacgtggac gaagaactca cagcagatat
    30121 ctatctctac cttgagtacg gagtaaaagt tcctaaggta gcggttgcta tccagaaagc
    30181 tgtcaaagat gccgtccgta atatggctga tgtagaactc gctgctatca atattcacgt
    30241 tgcaggtatc gtcccagata aaacaccaaa accagaattg aaagatctat ttgacgagga
    30301 cttcctcaat gactagtcca ctattagaat ctagacgcca actccgtaaa tgcgcttttc
    30361 aagctctcat gagccttgag ttcggtacgg atgtcgaaac tgcttgtcgt ttcgcctata
    30421 ctcatgatcg tgaagatacg gatgtacaac ttccagcctt tttgatagac ctcgtttctg
    30481 gtgttcaagc taaaaaggaa gaactagata agcaaatcac tcagcattta aaagcaggtt
    30541 ggaccattga acgcttaacg ctcgtggaga gaaacctcct tcgcttggga gtctttgaaa
    30601 tcacttcatt tgacactcct cagctggttg ctgttaatga agctatcgag cttgcaaagg
    30661 acttctccga tcaaaaatct gcccgtttta tcaatggact gctcagccag tttgtaacag
    30721 aagaacaata aaaagaaaaa gtgtttgata gatatcaaac act
//
LOCUS       DAVMAH010000026        30293 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVMAH010000026 DAVMAH010000000
VERSION     DAVMAH010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30293
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.026"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(<1..2019)
                     /locus_tag="VYO94_001095"
     CDS             complement(<1..2019)
                     /locus_tag="VYO94_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HEV1759742.1"
                     /translation="MFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYVASVTNVNLQSYAKRRKRSVDSIEQLLASINAAVFSGNTIVNGAPAINASINIA
                     KSEEKVYTGEGVDSFYNIPIYYQLTVTNDGSKLTFTYTVTYVNPTTKILGNISKKMSN
                     GYSIYNTGTSTQTMLTLGSGLGKPSGVKNFITDKDGGQVRYYNMSTMTTQGSGYTWGN
                     GAQMNGWHAKREHGLTSSWTVPITGTDTSFTFTPYAAKTDRIGINYFNGGGKVVESST
                     TSQSLSQSKSLSVSASQSASASASTSASASASTSASASASTSASASASTSASASASTS
                     ASASASTSASASASTSASASASTSASESASTSASASASTSASESASTSASASASTSAS
                     ASASTSASASASTSASASASISASESASTSASESASTSASASASTSASASASTSASAS
                     ASTSASTSASTSARTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSAS
                     TSASTSASASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSA"
     gene            complement(2017..2130)
                     /locus_tag="VYO94_001096"
                     /pseudo
     CDS             complement(2017..2130)
                     /locus_tag="VYO94_001096"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(2373..2834)
                     /locus_tag="VYO94_001097"
     CDS             complement(2373..2834)
                     /locus_tag="VYO94_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1759743.1"
                     /translation="MGKERRKQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     DRYLYRPYAGAPRGEKVYGKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(2801..2944)
                     /locus_tag="VYO94_001098"
     CDS             complement(2801..2944)
                     /locus_tag="VYO94_001098"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV1759744.1"
                     /translation="MAYSTDFKQGALDSIKGGHRHVEAAKVFDVGVRTLFTWEKKDVN
                     KGT"
     gene            3213..3593
                     /locus_tag="VYO94_001099"
     CDS             3213..3593
                     /locus_tag="VYO94_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1759745.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRVCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            3692..3913
                     /locus_tag="VYO94_001100"
     CDS             3692..3913
                     /locus_tag="VYO94_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1759746.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            3930..4244
                     /gene="trxA"
                     /locus_tag="VYO94_001101"
     CDS             3930..4244
                     /gene="trxA"
                     /locus_tag="VYO94_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1759747.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQSPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            4550..5083
                     /gene="queF"
                     /locus_tag="VYO94_001102"
     CDS             4550..5083
                     /gene="queF"
                     /locus_tag="VYO94_001102"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV1759748.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLLQHDLYPEKIDNR"
     gene            5095..5313
                     /locus_tag="VYO94_001103"
     CDS             5095..5313
                     /locus_tag="VYO94_001103"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759749.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVADRTDEVSLKHCFEVADRTDEVS
                     NHTYGKVKLTWFEEIFEEYHTKKPCSSR"
     gene            complement(5338..6006)
                     /locus_tag="VYO94_001104"
     CDS             complement(5338..6006)
                     /locus_tag="VYO94_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV1759750.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(6117..6908)
                     /locus_tag="VYO94_001105"
     CDS             complement(6117..6908)
                     /locus_tag="VYO94_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV1759751.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALIYANLLSADANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHSFAHGADLLKEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(7155..8951)
                     /gene="pepF"
                     /locus_tag="VYO94_001106"
     CDS             complement(7155..8951)
                     /gene="pepF"
                     /locus_tag="VYO94_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1759752.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALAAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISIDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(8962..9705)
                     /locus_tag="VYO94_001107"
     CDS             complement(8962..9705)
                     /locus_tag="VYO94_001107"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV1759753.1"
                     /translation="MQQYFVKGSAVSPVTIEDRETSKHMFQVMRLKEDDEVTLVFDDG
                     IKRLARVLDVEARQFELVEELDDNVELPVQVTISSGFPKGDKLEFITQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNVVPSIHLFENKADFLAQLDQ
                     FDRILVAYEEAAKEGEAAALIKAVTGLEKGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(9707..10660)
                     /locus_tag="VYO94_001108"
     CDS             complement(9707..10660)
                     /locus_tag="VYO94_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV1759754.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTVL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEMIIKLDPGMAFGTGTHPTTKM
                     SLFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEDYLIMSGIIKDK
                     WDMVRESAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            complement(10795..11223)
                     /locus_tag="VYO94_001109"
     CDS             complement(10795..11223)
                     /locus_tag="VYO94_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1759755.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(11204..12292)
                     /locus_tag="VYO94_001110"
     CDS             complement(11204..12292)
                     /locus_tag="VYO94_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HEV1759756.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYQLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVGITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(12311..12781)
                     /locus_tag="VYO94_001111"
     CDS             complement(12311..12781)
                     /locus_tag="VYO94_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV1759757.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPKY"
     gene            complement(13072..13524)
                     /locus_tag="VYO94_001112"
     CDS             complement(13072..13524)
                     /locus_tag="VYO94_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV1759758.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(13561..13740)
                     /locus_tag="VYO94_001113"
     CDS             complement(13561..13740)
                     /locus_tag="VYO94_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV1759759.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGK
                     LNKYTERGIRKQAGL"
     gene            complement(13877..14056)
                     /locus_tag="VYO94_001114"
     CDS             complement(13877..14056)
                     /locus_tag="VYO94_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759760.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(14221..14460)
                     /locus_tag="VYO94_001115"
     CDS             complement(14221..14460)
                     /locus_tag="VYO94_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759761.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            14730..16001
                     /locus_tag="VYO94_001116"
     CDS             14730..16001
                     /locus_tag="VYO94_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV1759762.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            16266..16338
                     /locus_tag="VYO94_001117"
     tRNA            16266..16338
                     /locus_tag="VYO94_001117"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16299..16301,aa:Lys,seq:ctt)
     gene            complement(16421..17548)
                     /locus_tag="VYO94_001118"
     CDS             complement(16421..17548)
                     /locus_tag="VYO94_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1759763.1"
                     /translation="MAYIEYKQRGKKKLWSFSIRERSKSLLHKSGFKTKREAKIEAEK
                     VLHKLNTGSVLSSSMTLSELYNEWLDLKILPSNRSVVTKKKYLMRKKVIERLFGNKPV
                     SQIKPSEYQKIMNEYGETVSRNFLGRLNSCIRASIQMAIADKVIIEDFTAYVELFSSK
                     SGQKVEEKYLHAESDYQKVLVYLKNKFDYQKSIVPYVIYFLFKTGMRFSELIALTWDE
                     VDELNEQLKTYRRYNTAIHKFTPPKNNTSIRLVPITSDMLSLLKTLKILQLKTNKELN
                     IDNENNLIFQHFGYVYDVPDIATVNKAIKVMLKELQIFPLITTKGARHTYGSYLWHNN
                     IDLGVIAKILGHKDISMLIDVYGHILEEKISEEFMAVKSLL"
     gene            complement(17550..17732)
                     /locus_tag="VYO94_001119"
     CDS             complement(17550..17732)
                     /locus_tag="VYO94_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEV1759764.1"
                     /translation="MKDTISNKDLISMGYRPSTANAIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVKELLGMEL"
     gene            complement(17748..18791)
                     /locus_tag="VYO94_001120"
     CDS             complement(17748..18791)
                     /locus_tag="VYO94_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HEV1759765.1"
                     /translation="MSKEILNRVVSNSPITIHQMSNKSYSKFQEEVSLKYGFIGLKLD
                     KLSLTAEVSEEFHSEILSGNFTLYDYFGVVEPNLNRNGELASYKGQFFNDEKENWYIE
                     YTPVASIKMNKRPLKIEFTPSKVSKKNFLIVFHRMFPYMFNIAISTFHLAYDFERDLS
                     ALRVNWPKVMYRPIYKGMKLETMDFGAPKGNYHLTAYNKLKERMDSGDMAEIEIYQQY
                     DNLWRIEYKFYNEGNIKKELKNGLPFLAKIPVYIENFKGLEFNNLGVNEKIYLFALRN
                     KPELFAESDKRTVAKYKKLAESISEVNLNVFFQNALDFVEIFNQEPCLINFFEFMNSM
                     LQGDIPKLTINQE"
     gene            complement(18917..19180)
                     /locus_tag="VYO94_001121"
     CDS             complement(18917..19180)
                     /locus_tag="VYO94_001121"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759766.1"
                     /translation="MKETVVVLAISTKKERGWIKVSTLNDCWSDLGMHFDKSKFGAVF
                     SAPGLYEVEVINNASFGQNAQYEVIQSRKLGTFAELIEMAKIK"
     gene            complement(19358..20680)
                     /locus_tag="VYO94_001122"
     CDS             complement(19358..20680)
                     /locus_tag="VYO94_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEV1759767.1"
                     /translation="MFKIKQTASLSEHYFLNTSKLRSIRWFTIGFLSMLSLSSSILFK
                     GWFLQMITLSVGLIITLYIERKIKGWAQQIEPLLIVRENLLFMLRRNSFLFTATKDGA
                     ILRSAKFNYQLNDVSIVIYAFKSGDEFTKEMDNLDVLLSSALGISLSSKEIYATHVEY
                     VFVYRQPERLHVTSLPLEDDSLKIKIYDDFVIDLRKNFSMLISGASGSGKSFFTYYYL
                     TRFISQTVNGKHAKIYVIDPKFSDIYKLCEFSGFPVENYGTTNEDAFRIVRHYINEMN
                     RRMEIYNKSDLFDSICIDLGFPPLLLVIEEYSSLIASMDAKAKKDFENMVAIVAQKAR
                     SLSMGVCIVMQQPRSDSLSTNIREQLVNAIFLGGSPSRESSQMMFGTTDVPKVQKGKG
                     VGLYSVERASPKEFHSPMFDRDVFETIFSVWECAAKDYAKDYMKDEDV"
     gene            complement(21156..21674)
                     /locus_tag="VYO94_001123"
     CDS             complement(21156..21674)
                     /locus_tag="VYO94_001123"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759768.1"
                     /translation="MNTETFKQKFIDGGYECPRSNEQTLRLQNIHFEYNLGFVFDKDS
                     QTYLRKILRLPYTYPCSMKMANSILLANMLVHKSTRETLVEWLNEEKQIHLDSFFLNM
                     NSSKYIKDGLLEEIRKNHRSIARKATPSNISLIEKELNYNSDLFYYYINALEWKHVKR
                     SYLVKCLAGAIA"
     gene            complement(21917..22330)
                     /locus_tag="VYO94_001124"
     CDS             complement(21917..22330)
                     /locus_tag="VYO94_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759769.1"
                     /translation="MKNNERLGIKLSRDSVLGLREVRRLYLGSSDIPVSDGYVIEVAY
                     KQISNEIDIIDWVELNKSKIKISEISESVDIDATSLRTTLTLDTLVYEGMRDIQLRLR
                     ELTKGRVFFSFVVKLVLFASILKKKGLLEKFQEKC"
     gene            complement(22727..24046)
                     /locus_tag="VYO94_001125"
     CDS             complement(22727..24046)
                     /locus_tag="VYO94_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1759770.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(24056..24901)
                     /locus_tag="VYO94_001126"
     CDS             complement(24056..24901)
                     /locus_tag="VYO94_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1759771.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            complement(24903..25805)
                     /locus_tag="VYO94_001127"
     CDS             complement(24903..25805)
                     /locus_tag="VYO94_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1759772.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMISLVQRRVLKEDD"
     gene            complement(25901..27211)
                     /locus_tag="VYO94_001128"
     CDS             complement(25901..27211)
                     /locus_tag="VYO94_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV1759773.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPTIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            complement(27338..28333)
                     /locus_tag="VYO94_001129"
     CDS             complement(27338..28333)
                     /locus_tag="VYO94_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1759774.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            complement(28695..30176)
                     /locus_tag="VYO94_001130"
     CDS             complement(28695..30176)
                     /locus_tag="VYO94_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1759775.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENRDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
BASE COUNT         9392 a         6439 c         5038 g         9424 t
ORIGIN      
        1 tgctgacgtg cttgccgatg tacttgcgct tgttgaagct gacgtgcttg ctgacgtact
       61 tgcgcttgtt gatgctgatg tgcttgctga cgtacttgcg cttgttgatg ccgatgtact
      121 tgctgatgcc gatgtacttg ctgacgtact tgcacttgtc gatgctgacg tgcttgccga
      181 tgtacttgca cttgtcgatg ctgacgtgct tgccgatgta cttgcgcttg ttgatgcgga
      241 cgtacttgct gacgtacttg cgcttgttga agccgatgtc cttgctgacg tgcttgctga
      301 ggtcgacgcg cttgttgatg ctgaagccga cgcactcgtt gatgctgaag ctgacgcact
      361 ggtacttgca gaggctgatg cactggttga tgccgattca gaggcactcg ttgatgccga
      421 ttcagacgct gagatacttg ctgaagctga ggcgcttgtg cttgctgagg ctgaggcgct
      481 tgtgcttgct gaagccgatg cactggtgct tgctgaagct gacgcactcg ttgatgccga
      541 ttcagacgct gaggtgcttg ctgaagctga agcactggtt gacgctgatt cagatgctga
      601 ggtgcttgct gaggccgacg cactggttga cgctgaagcc gatgcactgg ttgacgctga
      661 agccgaagca ctcgttgatg ctgaagctga ggcgcttgta cttgctgagg ctgatgcact
      721 ggtgcttgct gaggctgacg cactggtact tgctgatgct gaggcactcg ttgacgctga
      781 agccgaggcg ctttgactag cacttactga gagtgactta gactgtgaaa gtgactgact
      841 ggtcgtgcta gattcaacta cctttcctcc accattgaag tagttaattc caattctatc
      901 tgttttagca gcgtaagggg taaatgtaaa ggatgtatcc gttccagtaa ttggtacagt
      961 ccaagatgat gttaatccat gttctctctt agcatgccaa ccattcattt gggcaccatt
     1021 tccccaagta tacccactac cctgcgtcgt cattgtagac atattatagt atcgaacctg
     1081 tccaccatct ttgtcagtaa tgaagttctt tacacctgaa ggtttaccaa gaccactgcc
     1141 aagggttaac attgtttgtg ttgaagtacc tgtattatag atagaatatc cattactcat
     1201 cttttttgat atattaccaa gaatctttgt tgtaggattc acatacgtaa ccgtataggt
     1261 aaaggtcaat tttgaaccat catttgtcac tgtcaattga tagtaaattg gaatattata
     1321 aaatgaatct acaccttcac ctgtataaac tttttcctca cttttagcaa tgtttatact
     1381 tgcattaatt gcaggggcgc catttacaat cgtattgcca gaaaaaacag cagcatttat
     1441 agaagccagc aattgctcga tggaatccac tgaacgcttg cgtcgcttag cataagattg
     1501 gagattgaca tttgtaactg atgctacata atcactagct ggtttcttac gatcttcttc
     1561 gaccttctta gcagttgctt ctgtagcggc agctgtttgt gatcctacca cagtagatga
     1621 tgcagagata cttgtcgaag ccgatgtact tgctgattct gatgcacttg tactcgctga
     1681 ggtcgaagcg ctggttgagg ctgactcaga tgcagatgta cttgccgact ctgaagctga
     1741 caaactagtt gaactcgctg aattacttgt agatatcgta cctagaacta ctgtatcatt
     1801 tgttgccaaa gcatccgttt tctctacagt tttttcaagt actgccgact catttgtaaa
     1861 taccttcgtt tgagttgcaa cggttccact tatgacagtt cccgcagcaa ctattccctt
     1921 gaggatatca agcccagtaa ttgaatgact tactttatct tctaccgttt cggtcatgac
     1981 ctgagtagta tcaacaccac cacgcatgac cttaaacaag ccaaaaagag aagtcgaggc
     2041 ccgtagccaa tgcttccctg atttgattaa tttgaaccga gttactcggt ctgtttctct
     2101 atattcaccc ttctgacgtc taaaaaatat tttgaaattt cctttcgagt attattttca
     2161 tgtatggata taaataaatt accatactat aattatagaa tagggaaccc aaaatagcaa
     2221 gaaacttgag gtatttttgc taaaaaaaaa agcattttac tattttgtat atatatatat
     2281 attataagat aagtttttta taaagacacg caaataagta taaatcagct aatttttggt
     2341 ttatattcct atttttatgc ataattattc tttcattctc taatttgtga atcaatatat
     2401 ctgattagaa aactaccatt gagtttttgc tccacctcat tagtccgctc aaaacgccgt
     2461 ccgctaatct tgccatagac tttctcccct ctaggagccc ctgcataagg acgatagagg
     2521 tagcggtcga ttcccgtttc gtcaatatat aggactggta aatcttttag gttatccaaa
     2581 atatcaagaa actcagaaac tttctcaggc ttttgttccc taaaactggt cgtctttttt
     2641 aaaatgacct taatctgctt taaaactgcc catacggagg gcaaagcaca atcaaaacgg
     2701 gccgcaattt cccgtaaaaa agcgtctgga tgagcctcta caaaggcttt caattcttct
     2761 aaagggatct tacgcttttt gacgactcgc tttttccgct ctaagttccc ttgtttacgt
     2821 ctttcttttc ccacgtgaag agagttctga cgccgacatc aaaaactttg gccgcctcga
     2881 catgtctgtg ccctccttta atggaatcta atgctccttg tttaaaatca gtactatatg
     2941 ccatagcttt attagaccat gcttatttta aactaagcaa ctatagatag agaaatgaaa
     3001 taaaatctga attcgaatgt gataaggagt tagaaattga aacaatagga tttccccatt
     3061 attcacacaa aaataaaacc actaaaaaac agagcttgcc agcattcttg aaaagtagta
     3121 taattattgc atgcgcaatc atcttgtgac gcagagactg cccgttaatg gactttcttc
     3181 tattttatga ctctaaaaag aaaggagaca ctatgaccta tttggaaaaa tggtttgact
     3241 tcaatcggcg tcagaaagaa attgaaagtc tcttggaaga gaccattgcc caacagagcg
     3301 agcaaagtct gaccttgaaa gagttctacc tgctctacta tctggacttg gctgaagaaa
     3361 aatctctacg ccagattgac ctgccagata agcttcatct gagcccgagc gcagtttcta
     3421 ggatggtggc tcgcttggaa gctaaaaatt gcggtctact cagtcgcgtg tgttgccatc
     3481 aagatagacg ctctagtttt atctgcctga caaatgatgg gcaaaagaca ctggcctcgc
     3541 tacaaaagac tgtcgaagaa agcttggaag caggtttgga tttcttgatt taagatgatt
     3601 ttaaaaaaag ttgcgtgcgc aatcattttt cttgacattc tcttttataa ggagtaaaat
     3661 aaagttagca ttaaacaaag gagttttaaa tatgattgaa attacctata tagatgccag
     3721 caagaacgaa agaactgtga ctttcgagtc ttatgaagac tttgaacgtt cgcaacaagc
     3781 ttgccttatc ggcgtcgcag actactaccc tgtccaaaaa ttaacttaca agggtcataa
     3841 tttggactac catgggactt atggagacat cttcttctat ctcatgaaac aagatttaag
     3901 ccaatataac taaaaaaagg agaaatacaa tggcaaaagc aattacagat gcaacattcg
     3961 aacaagaaac aaaagacggt ttggtcttag tagacttctg ggcaacttgg tgtggtccat
     4021 gtcgtatgca aagtccaatc ttggacaaat tgtctgaaga actttcagaa gatgtcttga
     4081 aaatcgttaa aatggacgtt gatgaaaatc caaacacagc tcgtgctttt ggaatcatgt
     4141 ctattccaac tcttctcttc aaaaaagacg gccaagttgt caaacaagtt gcaggtgttc
     4201 acacagcaga acaaatcaag gccatcattg ctgaattgag ctaatcaaac gagagaccaa
     4261 gtactttctt tggtctcttt tttcttgccc tttgccattt ttcaaaaaat atgctagact
     4321 atagtagatt gaaactagaa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     4381 tgactgccct gatcgatttg tcctgttctt atttcatttt actatataag tagaatatta
     4441 cgatgtttgg gatatgccat cgctaaaaaa aactcgattt ggtatttttt agctccctaa
     4501 tgggagcttt ttgcgtgctc tgaacatttc ccattttgga aggagtactg tgaaacgtca
     4561 atcagccttg gtcgtcttta gtggtggtca agattcaaca acctgccttt tctgggccat
     4621 gcaacactat gaaacagtcg aagctgtcac ctttgcctac ggccaacgtc atcacctcga
     4681 aattcaaatt actagagaaa tcgctaagga acagggcatt cgtcaccata tcctcgatat
     4741 gtctctgctg ggacaaatca ctgctcagcc agactttgcg acgattcata tttcctacat
     4801 tcctgacaag ctctgtgtcg agtcaaaatc cctcaaacta tatctattta gctaccgaaa
     4861 ccacggagat ttccacgaaa actgtatcaa caccatcggg aaagacttgg tcaacttgct
     4921 agaccctcgc tatttagaag tctggggaaa attcactccg cgcggtggca tttcaatcga
     4981 cccctactat aactacggta agcaaggaac taagtatgag ggcttggcag aacaacgcct
     5041 cctccaacac gacctttatc cagagaaaat tgacaaccgc taaagtcata ctcaatgaaa
     5101 atcaaagagc aaactaggaa gttagccgca ggttgctcaa aacactgttt tgaggttgca
     5161 gatagaactg acgaagtcag cttaaaacac tgttttgagg ttgcagatag aactgacgaa
     5221 gtcagtaacc atacctacgg caaggtgaag ctgacgtggt ttgaagagat tttcgaagag
     5281 tatcatacga aaaagccctg ttcctcaaga tgaggagcaa ggctttttga gtttcaatta
     5341 ttcttctgtt ccaaggaaat tttttgcaac aagggctgca agaactccac cagcgattgg
     5401 tgcaaggatg aaaatccaaa cttgttgaag ggctgcgccg cctaccaaga cagctggtgc
     5461 caagctacga gctgggttta ctgaaagtcc agtaatcttc aatccgacaa gaatcatcgc
     5521 catcaatgac aaaccgatta ccaaaccagc aatcgcgcca ttgcccttgc tttctgaagt
     5581 cacagtcatg ataaccaata caaacaagaa agttgcgatg acttcaaaca agaaaccacc
     5641 aaagacagtg acaccgtttg ccaaggcatt ttcaccaaga ctagcagttg acatacctga
     5701 gttagccaag aggaagaaga cagcgccaga agcgatgaaa gctccaacaa cctgaccaag
     5761 gatgtagttt acaagttctg aagatgacaa acgtttgttt acaaacatag caatcgaaac
     5821 agccgggttc aagtgagcac ctgaaacagt tccgattgag taggctgcca ccacgattgc
     5881 caaaccaaag gcaaaggcga ttccaaggtg accaaggcca tcaagaccat ttccaaaaac
     5941 aacagctcct gtcccaacga acacaagcat gaacgtaccg attaactcag caacaaattt
     6001 tttcattttc tttctccttt tttcaaaaac tagatactag tctatcaaaa gtaggaaagg
     6061 gtttcaagaa aattgattgg aaattttttg aaaatcatag aactattagc taatctctag
     6121 tattgaaaag actggatagc ttctttcaac tcatcttgta aactatttct ctggtcaagt
     6181 tggacataga cttccaccag acaggatcta aagttggaaa atttgtaaaa atcctccctt
     6241 tcttctatcg gaaaatcaac agtttttatc caagaagcta cttgttcttg ctccaacttc
     6301 ccttgtaaaa taggttcata gatcactctt gctaaacgcc aatcctcatc atctgtaaag
     6361 cgaatcgaca ttcttttaaa tagttggcca agtatatcaa atacttcatg aactctgttt
     6421 ttaggaaagt ctggatgaca aaccacctct ttcagtaaat cggctccatg tgcaaaagaa
     6481 tgaacccaac catactgact tgagaaacct gttgtatcct tttcttttga aagatagtgc
     6541 aagccttgat ttaaaaggac attacgaatt tctgattgta atccctgata aaaaaccgat
     6601 tgctggttgg catctgcaga caagagattt gcataaataa gtgccctaaa agaacgttca
     6661 agtgttgaca gacctacctt atcaatctct ttatctaacc ctccatcagc taagaccacc
     6721 tcagcaatga aatgaaattg ctcctgtgta aatagctctt cctgaatccc tctagcaaag
     6781 cttgtaaaaa caagatcatc acgaatttct ggagaaggat ctcccaaatg atcaagcaac
     6841 cactggattt cctcctggtt ataatttggt ttttcttctg ctatttttct tagtaaatct
     6901 tgatacatgg tcaatacctc tacatttcta gcaactgttc aaaaaggcag tcttaaatga
     6961 ctcaatattg aattctcaat taaatacaat ctgatataaa atgacgtaaa taactatcaa
     7021 taccagttct acagtaagtt caaatttaac atcacgacct tcaacgacat ttttgaaaat
     7081 agctacaact aagacaaata gaatgacgct taacaagccc ataaacatca ttctagaaaa
     7141 tttttctatt ccccttactc ccccaactca gcactgtagg cgataatctg gtcaactgtg
     7201 tcagacaaga attggatggt atcacggagt ggtttgtcta ttgaaatatc agcaccgata
     7261 atcatggctg actcaagtgg tgtcttgcta ccacctgatt tgaggagatt gagccagtct
     7321 tcagctccag tttcagaatg ttttagatga aggtaaccag cagtcgagat aactagtcct
     7381 gctgagtaag tgtaactata caagcccata tagtagtgag cttggcgcat ccaagtcaga
     7441 gttgcatcat cgtcaatttc aatagcatct ccccagaaat ccgtcaaaac ttccttcata
     7501 atgctgttga gcttgcttgc tccaaaggtc tccccttctt caatcaatgt atacacctta
     7561 cgctggaagg cggcttccaa gaggtgggtg atgaaattat ggaagtaggt gtctgtcaag
     7621 cgatgagcca gagcgaagcg tttttgacgt gggtcattag actggttctc taagtaatca
     7681 ctgagtagca attcattgaa ggtcgacggt gcttcaacat aataggtcga catgtgggca
     7741 ttgaaatagc tttgatgatt gtctgaaaag atgaattgac cagaatgccc gatttcatga
     7801 atcaaggtat agacatcgct caaacggcct gtccagctca tgagtacata agggtgtacg
     7861 cgatatgggt ccgccgcata accaccggaa tccttgccac tgttagcagc aaagtccacc
     7921 cagcgctctt cttggtaacg agcaacttcc tgacaatatt cttgccccaa aggttctacc
     7981 gacttcatga ccaaatcata ggcatcgtca atagtcactt caggattcag ggcgctgtcc
     8041 aagtccaatt tccagtctgc aaaggtcatc ttttcaagac catttacctt ggcaacatgc
     8101 ttgaggtatc tctgagcgac tggtgcaaag tccttcatga tgaggtcaat ctggcggtca
     8161 aacatgacac ggtccacttc ttgttcagct agaagatagt caaagacaga gtcgtatccc
     8221 ttcatatcag ccaagagttt ttcagacttg acctgagcca gataggctgc tgcagccgta
     8281 ttttggtgct tacgaagtcc ctctgagaag gaacggaagg atttctcacg aacctcagca
     8341 tcctcatggt tttggtagaa attctcatag gtcacaaagc tgtttttgta ggtcttgcca
     8401 tgggcttcaa agtcagccat ttcaaaatcc ccagctcgca tcttagtata aatgtcctgc
     8461 ggactataga aaacttcacc gagattggtc aaggccttct ccacatctgc ccctaagtag
     8521 tgggcttttt tgattttagc ctgacgaatg gcagctgtta aatgtggcaa tttacccaaa
     8581 cggtccaaga cttcctcgtc tgctgccgcc aaggcatcgt caaaaaaggt caaggctacg
     8641 ctggcatctg tttcaaattc catcccagct tgagcaatat ttgcaaattc gtcattgcta
     8701 tagtccgtcg tctgaggcat aaaagcatag ttgccaatat ggctcatctg aatgtagatc
     8761 tgttccaatt ccgcaaaggc cttctcgaaa tcctcaaaag tgtgaagatt gcccttgtaa
     8821 tcacggctaa actggttgat gtcttcgcga gctttctcga ttgcacgcaa gaaatcctca
     8881 cggtcttggt atagagctgt taaatcccaa agttccttct ctggaaattc tgaacggtgt
     8941 ttttgttcca ttttcttcct cttatttctc taattctact aaaacactaa gggctgataa
     9001 agcgtaaagc ggtgctgttt ctgctcttag aatgcgaggg ccaagtcctg ccaaaacagc
     9061 tcccttagct tcaaaatttt caatttccgc aggtgacaga ccaccttctg gaccaaagat
     9121 aaagagcaat ttggctcctt tctcgagtcc agtaactgct tttataagag cagcggcttc
     9181 tccttctttg gccgcctctt cataggctac taagatgcgg tcaaactggt caagttgggc
     9241 tagaaagtct gctttattct cgaaaagatg gatacttgga acaacattac gcttactttg
     9301 ctctgctgct ccaagagcaa ttttttctag tttttcaacc tttttaccca atttcttgcc
     9361 atcccacttg gcaactgacc agtctgcagg aaaggcccaa atctggctgg cacctagttc
     9421 cgtcaccttt tgagtgataa actccaactt atctcccttg ggaaaaccag atgaaatggt
     9481 cacttgaacg ggcagttcca cattgtcatc tagttcttct accaattcaa actgacgagc
     9541 ttccacatcc agcacacgcg ccaagcgctt aattccatca tcaaagacca aagtaacctc
     9601 atcatcttct ttcaagcgca taacctgaaa catatgcttg ctggtttccc tgtcctcgat
     9661 ggtgacagga gagactgcac tccccttgac aaaatactgt tgcatcctag cctccaatca
     9721 cacctgaaat atccttggtc ttcttgaaga cgcaggcatt ccattcccct tgaatcatat
     9781 gggtttcaag gaaaaatcca gctgattcag ccgactcgcg caccatgtcc cacttatcct
     9841 tgataatgcc actcatgatc aggtagtctt cgtccttaac caaacgatag gcatcgtcta
     9901 ttagatgaat gaggatatcc gccaagatat tagccacaat gacatctgcc tcaatttcca
     9961 cacccttaag caaatctcca gccgctacat ggatattttc catgccaggg ttgagctcaa
    10021 tattttcctg agccacacga accgccacat catccaggtc ataggcgaaa atttctttag
    10081 cccccagaag cgagctggca atagagagaa cccctgaacc agtccccaca tctagcaccg
    10141 tttcgccacc acgaagaacc tgttccaagg caaaaaggct catcttggta gttgggtggg
    10201 ttccagtacc aaaagccatg ccaggatcca gcttgataat catttccccc gcagtcgcct
    10261 catagtctgt ccaagaggga acgatggtca aatcatgagt gatacgagct ggctcatagt
    10321 atttcttcca gttatctgcc cagtcttcct cagccaagac agtcgtacct atttttaact
    10381 ctcccaaatc cataaaatcc gtcaattctg ctaagcgagc ctgcaagtcc gcctcaacca
    10441 ctgtcacatc caccgtgtca gggtagtagg ctgtcactac gatttcttct tgctgctcca
    10501 cctctgggaa aatctcgcca aagcggtcaa catttcccac atagtccata ctgtcttcaa
    10561 tcgcaacacc ttgcgctccc agctcaatca agagattgga aaccaactcc tctccctcac
    10621 gcttcactgt aacttttaac tcttgccatg tttccatcat taagatacca agcccgtaaa
    10681 acacaaaacc aaaataggaa attctctgaa gacgtttgtg tctaagagaa gtttatcttt
    10741 ttggcaccgt gtttagggcg ggttcagttt agaaatttaa ctgaaccatc ctttctaatc
    10801 acttactttt aaataatctt ttaatctctc ttgcaactga ggcacaactt gactggaact
    10861 aagaaattcc tcaacattca tcagctgata gccctgtcct tcatctccaa atacgatact
    10921 gtcaaactgg ttctgtgtca actgaccaac tagaaaaacg gactgtttgt ctgcaaaaag
    10981 catacttggg taaaccttac tccaaagcag acaatcttca gtcagatgaa ttcccagttc
    11041 ctcataaact tcacgccgag cgcattcaaa agggctttcg tccccttcac ggccaccacc
    11101 tggcaactcc cacatgttgg gacaagggat atcgtccttg tcatcacgca aaatcgtcag
    11161 tagcttatcc ccacaaaaga gggcaatctt gcaaccttgg aaatcagaaa tttctagttc
    11221 catcttcagt tccttctaac atttcctttt ccagctctgc taacaagttt tcataatagc
    11281 gtttctcgtc cctcaacatt cgactactat ccattttctg tctagcaatc ttgagagcct
    11341 tacgagttcg atctacatct ttcttcacct ttaattgata ccaggcttgt atcacttgaa
    11401 gattggacag tttgagagac agaaacgatt tgacctgtcg aatactagca tattgctccg
    11461 cttgctcaaa atctccttcc aacaaggcga tatgaagtag ggatagttgg gcaactgtct
    11521 gcatcatcgg agtagttgtc ctctcaagta atgcttgaaa ctgctgttta gctacttctt
    11581 ccttcccttc caaaatggaa acttcacctt gcatacctaa tacaccatcc gcaaaactcc
    11641 ctcgtgcatc ctcaggaact gcttgaacaa agtctttcaa atcatattct tgaggagcca
    11701 gcaaagtttg agcagaatgt ctcaatacca ggtaggcgta tttggtattt tcagggtgtt
    11761 gtagtaattc ccaaattttt gctccatcgg tgatgccgac tggtaaaatg ttatttagga
    11821 agaaagataa attaagaaaa atccaagtcc ctgcaaaata ccagcttctt gtcaaaaatc
    11881 caaacactat cgccaataat atcaagccga gatgaaccat caagcctcct gaaagcatca
    11941 ggatgattct ttgatcgctt tcatcctctt ttaaaccaat gtattgagca ccaacatttt
    12001 tcagaatggc tgttctacta agatgaaacc tgcctgactt ttttgtcaaa ataaaatgtc
    12061 ctaatccaaa agccaccagc tgatagcctg tcaagtagcc acaaaaagca tgacccagct
    12121 catgaagaat aaagattaaa tacatgctta gaagagcgaa ggcataacca aaagtaaagg
    12181 ctaaaactgc ggaatacccc aactctgcaa atgcgattgt tccacaagca aaagctagca
    12241 taataaagac aacagctagc acataaacca aataagtccc aattttcttc ataacacctc
    12301 caaccaactc ctagtatttt ggataagggt aaaattctcc ctcttccaag ccaacttttc
    12361 cttcttcaaa gacttcttga ttccattcca taacaaattc ctctgcttct ggatcttcca
    12421 aaaagtccat gagggtatct agcccaacct ccgcagtatc tttgaggaaa agggcaaaat
    12481 aagctaaaaa ctcgcgagaa aatccttttt taggtagata agggataacc gttaaatagt
    12541 cttctgcatt gacggttgac ttggcaggat tgtagaaaag gaccgcttcc tcaaaaagaa
    12601 tgtcatctga tgaaacctct ccgtcttcat ccaccatctc cacacctgca gcattttgcg
    12661 cttccaatag aaaactcact tctaccgcgt ggttacgctt gtcccaacta atctcaaagt
    12721 caaagggaaa gttcttgtcc aactcttcct ctaaaatatc taaaaatccg tatgttgcca
    12781 ttttgtcctc tttctatgcg actctttaat cgccccgatt gctcggaaat atgctaaaat
    12841 agatactacc atcttaccac aaaattattt tatgtcctaa ttataccata ttacctcatt
    12901 taaacccttg gtatcagtga ttttcttaaa agtctgattt cttcatttct cataaaaatc
    12961 aatataaaaa gcccgcgaaa gggctaataa atctataaaa tcaataggcg agtaactagc
    13021 acaagtggac gtgctttttt attgactatt accacgatac cacgcttaat cttaggcttg
    13081 aactttctta tctgcaatag catctgtcaa agtctgagaa aagttaagtc ccatttctcg
    13141 tcccaactta tctgcccatt ttggtatggt caaagtcttt ttaatgggtt cctgacttcc
    13201 taggtattct gatacatcaa cagataccat agaaataaaa gatttatcaa ggtcataggt
    13261 tgacacgaaa tcttcatcat ctttaaaagg atcattatca attaaagaca agctattgat
    13321 atctgatggc tgaggtaact ctccatcact ctctatcaaa tctgcaacag ttatccctag
    13381 ccactccgac cccatagcca aagcctcaga aatcccctct ccttgtgtgg ctgagtattc
    13441 aaaatctggg aaatggacaa aataagtcgc ttctgttccg tctgtgtcgt cataataaaa
    13501 taaagctgga tacgtaacta acatttcact acctccatat caaaaagcag gggctgaatt
    13561 ttacaaccca gcttgctttc ttatccctct ttcagtgtac ttattcagct taccatgaag
    13621 gattgtgata ggtctttccc cttgcttttc cattttaata tgggagcctt taccgcctct
    13681 agtctttatc caaccatggg ccgtaaggag tttaaccatc tctttttgtg tcataggcat
    13741 agcgctttta cctcctgaca acaccattat aacacgtgtt acacgtattg taaaggagtg
    13801 atacttatta ttctattata cataaaagcc cctagatgtg gttctaaggg aagccaattt
    13861 attcagacct atttttctaa tgagtagtaa aaactgcttc tttatcgagc aattcatcat
    13921 ctgtatagtc aattgtaaaa gtatctcgat ctaagacaga ttgaggcgga gttgaatgaa
    13981 tcataggaac actgcgtact ctatattttt tatctccaat ttttacaaac tgatactctt
    14041 cgaaaatcaa attcaaacca cgtcaacgtc gccttaccgt actcaagtac agcctgcggc
    14101 tagtttccta gtttgctctt tgattttcat tgagtatgat taactctcaa gtcttcgaaa
    14161 tcaggatttt caacagttat tacaaggatg cgatttacta cttcaaaaac atcaattatt
    14221 ctatttttca tattttttca acccattatt agaatgaact tcttggtaag caaaatcaag
    14281 tttagattta atgttttcgt acaaatctaa aatctctttt ggagtatctt cccggaagaa
    14341 aagttttctt ttccctgaaa taacttgatc actaagaatc caatgacgaa tttgttttgt
    14401 aaaaatcaaa atttcctgac ttggtccatc atttccattg cttatcacct ctcttttcat
    14461 tatagttcat acaatgacat ttagcaatat tatttctcaa gtcagcactt ccacttcttt
    14521 aggctcaact atcctatttt gagctttaag gaaaatcaaa tctctcatgc tgatacctct
    14581 cctcattaaa ttaaatagta aaaaagattc tatctcactc cctgattatt acaaaaccat
    14641 tgaaatatca caactaatag gctagaatgg acatagtaag atatagtaga tgagtcattc
    14701 tactcaaatc cacgttagaa aggactgcta tgccagacaa tctcgcgctt cgcatgcgcc
    14761 ctaaaaccat cgaccaggtc atcggtcagg agcatctggt cggacctgga aaaatcatcc
    14821 gccgcatggt ggaagccaac cgcctgtcct ccatgattct atatggccct cctggaatcg
    14881 gcaaaaccag tattgcctct gccatcgctg gaacgaccaa gtatgccttt cgaactttca
    14941 atgcgacagt tgatagtaaa aagcgactgc aagaaatctc ggaagaagct aaattttctg
    15001 gtggtctcgt cctattgcta gacgaaattc atcgactaga taagaccaag caagacttcc
    15061 tcttgcctct cttggaaagt ggactggtca tcatgattgg agcaacgact gaaaatcctt
    15121 tcttctctgt cactcctgcc attcgtagcc gtgttcaaat tttcgagttg gaacctctgt
    15181 ctaaccaaga cgtcaaagag gccctgcaga tagctctaag taaccctgaa cgtggttttg
    15241 attttccaat agaactagat gaggatgcgc tggatttcat cgcaacctct acaaacggag
    15301 accttcgctc tgcctttaac tcactggact tggctgttct ctctacccct gagaatgacg
    15361 agggcattcg ccacatcacc ttagacatca tggaaaatag tcttcagaga agctacatca
    15421 ctatggacaa ggatggagac ggtcactatg atgttctatc tgccctgcaa aagtctatcc
    15481 gtggctcaga tgtggatgcc agtctccact atgctgcccg cttgattgag gctggggatc
    15541 tgcctagtct cgctcgtcgc ttgactgtta tcgcctatga agatatcggc ttagccaatc
    15601 ctgaggccca gattcatacc gtgactgctc tggatgctgc ccagaagatt gggtttccag
    15661 aagcccgcat tctcattgcc aatgtcgtga ttgatttggc cctttctcca aaatccaact
    15721 cagcctatgt agctatggat aaggcacttg ctgacctcaa aacatcaggg cacttgccta
    15781 ttccgcgaca cctgcgtgat gggcactaca gtggaagcaa ggaactgggg aatgcccaag
    15841 actatctcta tccacacaac tatcctggaa attgggtcaa gcaagactat ctgccagaaa
    15901 aaattcgtaa tcatcactat ttccaagcag aagatactgg taaatatgaa cgggctttgg
    15961 ctcaaagaaa ggaagctatc gaccgtttgc gaaaaatctg aaatcctttt caaaaaattg
    16021 cactttcctc ttgatttttt ttaaaaaagt ggtatcatat aaatatagaa acgctgtggt
    16081 gtacgacttc acacttaagt gttgaccgac tattttttgt attattaggg aaacaaaagt
    16141 cttctaacag catgtaggcc gtctcacacg gaaacagctt cagttagagc gagttgccca
    16201 cctgcttaat tgcgcgggtt caatacaaac cgtgaagttt cggcaccaat acagcttttt
    16261 tctttgcctc cttagctcag ctggcagagc agcggactct taatccgtgg gtcacaggtt
    16321 cgatccctgt agggggcata taaatacaac aggaaaagcc ttataatata gggctttttt
    16381 tgctttcctt ttaaaaattg tcgtgcaatt tgccgtgttt ttacaacaaa cttttcacag
    16441 ccataaactc ctcactaatt ttttcctcca agatatgccc ataaacatca atcaacatgg
    16501 agatatcttt atgtcctaaa attttcgcta taactcccaa atcaatatta ttatgccata
    16561 aataactacc ataagtgtgt ctagctcctt tggtagtaat caatggaaaa atttgcaatt
    16621 ccttcaacat tacttttata gctttattga ctgttgcaat atctggaaca tcgtagacat
    16681 agccaaaatg ctgaaaaatc aaattatttt cattatcaat atttaattct ttatttgttt
    16741 ttaattgcaa tattttcaat gtttttaaca aggaaagcat atctgaagta ataggaacta
    16801 atcttattga agtattgttt ttaggtggag taaacttatg aatagcagtg ttgtaacgac
    16861 gataagtttt aagttgctca ttaagctcgt caacttcatc ccaagttaga gcaatcaatt
    16921 cggagaaacg catgccagtt ttaaaaagga aataaattac atacggtaca atagattttt
    16981 gataatcaaa cttatttttc aaatatacta aaactttttg ataatctgac tcagcatgca
    17041 aatacttttc ctcaaccttt tgtccactct tagaagagaa caactcaaca taagcagtaa
    17101 aatcctctat tatcacctta tcagcaatag ccatctgtat acttgcccga atacaagaat
    17161 tcaatcttcc taagaaattt ctcgatacag tctctccata ctcattcata attttttgat
    17221 actcgctagg cttaatttgt gatacaggct tatttccaaa taacctttcg atgaccttct
    17281 ttctcatgag atattttttt ttagtaacta cacttctatt gctaggtaaa atttttaaat
    17341 caagccattc attataaagc tccgataaag tcatactaga gcttaagaca ctcccagtat
    17401 ttaacttatg aagaactttc tccgcttcta ttttagcttc tcgttttgtt ttaaatccgc
    17461 ttttatggag taggctcttg cttctttctc ttatagaaaa ggaccaaagc tttttcttcc
    17521 cacgctgttt atactcgata taagccattt cacaattcca ttcccaacaa ctctttcaca
    17581 acactttttg gaacaaccat caaacgtttg cgattataaa atgtatagcc tcgagataca
    17641 agtaattctc tcgcctgatg gataatagca tttgctgttg atggtctata gcccatggaa
    17701 atcaaatcct tattagaaat cgtatctttc atactgttcc cctcttatta ttcttggttt
    17761 attgttaact ttggaatatc gccttgtaac atagaattca taaactcaaa aaaatttatc
    17821 agacaaggct cttgattaaa gatttcaaca aaatctaaag cattttgaaa aaagacattc
    17881 aaattaactt cagagatact ttcggcaagt tttttatact tagctaccgt tcgtttatca
    17941 gattctgcaa ataattcagg tttattacga agagcgaaaa gataaatctt ctcattaact
    18001 cctaaattat taaattctaa gcctttgaaa ttttcaatat acactggaat tttagctaag
    18061 aatggtaatc cattttttaa ttcttttttt atgttgcctt cattgtagaa tttatactca
    18121 atcctccata gattatcata ttgctgataa atttctattt ctgccatatc tccactatcc
    18181 atacgttctt taagtttatt ataagcagtt agatgataat tacctttagg agcaccaaaa
    18241 tccatagtct caagtttcat ccccttataa ataggacgat acattacttt tggccaattt
    18301 acacgtaaag cagataaatc tcgctcaaaa tcataggcta aatgaaaagt agagattgcg
    18361 atgttaaaca tgtacggaaa cattctatga aagacaatta aaaaattctt ttttgaaact
    18421 tttgaaggag taaattcaat ctttaaaggt cttttgttca ttttaatcga cgcaacgggg
    18481 gtatactcga tataccaatt ctctttttca tcattaaaga attgcccttt ataactagct
    18541 agttcaccat ttctatttaa attcggctca actacaccga aataatcata taaggtaaag
    18601 ttcccactaa gaatctcaga atgaaattcc tcactaactt cagcggtcaa acttagctta
    18661 tccaatttca gaccgataaa cccatacttc agagatactt cctcttgaaa tttagagtaa
    18721 ctcttattag acatttgatg tatcgttatc gggctattag aaacgacccg atttaaaatt
    18781 tctttactca tgaaatttct ccttcaaaaa aacaaaacat tctatatact taaattttag
    18841 ggcaagactg ccgttccact gaccacgctc cacttgccag caaagctggc aggtccagcc
    18901 ttaccctaaa tataaattat ttaatttttg ccatttcaat caattctgca aaggtcccaa
    18961 gctttctgga ttgaattacc tcatattggg cattctgtcc aaatgaagca ttattaatca
    19021 cttcaacctc ataaaggcct ggagcagaga aaacagctcc aaatttggat ttatcgaaat
    19081 gcatacctag gtcactccaa caatcattaa gggtggagac ttttatccag cctcgttctt
    19141 tcttagtaga aatagctaga acaacaacag tttctttcat agttaaaaaa tccttcctta
    19201 tttaaaataa tatacagctt ttaacgtcaa tcagtattgg acataaatac atttattcga
    19261 acgttcgttc gaaccggcct tgttgttcgc cggctgcaca atggcatttt gaaaatgaat
    19321 aaaagaattt tattcatctt caaaacgctt aaaattctca tacatcttca tccttcatat
    19381 aatctttagc ataatcttta gcagcacatt cccaaactga aaatattgtc tcaaatacat
    19441 ctctatcaaa catcggagaa tggaattcct taggagacgc tcgctccaca gaataaagtc
    19501 ccaccccttt gcctttttga actttcggca catctgttgt gccaaacatc atctggctac
    19561 tttccctact ggggcttcct ccaaggaaaa tagcattgac caattgttca cgaatatttg
    19621 ttgaaaggct atcggaacgg ggttgttgca taacaatgca gacccccata gataaagacc
    19681 ttgctttttg agcaacgata gcaaccatat tttcaaaatc ttttttagct ttagcatcca
    19741 tcgaagctat taacgatgaa tactcctcta ttactaacag taaaggaggg aaacccaagt
    19801 ctatgcaaat gctatcgaac aaatcgcttt tgttgtaaat ttccatccgc ctattcatct
    19861 cgttaatgta gtgacgcacg attctaaagg catcctcatt agttgttcca taattttcta
    19921 ctggaaaacc agaaaattcg cataatttat aaatatctga aaattttggg tcaatcacat
    19981 atatttttgc atgtttccca tttacggtct gagatatgaa acgagtcaag taataatatg
    20041 taaagaatga tttaccacta cctgaggccc ccgatataag catggaaaag ttttttctca
    20101 aatcgataac aaaatcatca tagattttaa ttttcaggct atcatcttca agagggaggg
    20161 aggtaacatg taaacgttca ggctgtctat atacaaaaac atattcaaca tgagtcgcat
    20221 aaatttcttt tgacgatagg cttattccta gagcactact taggagaacg tctaaattgt
    20281 ccatctcttt cgtgaattca tccccagact taaatgcata gattacaatt gaaacatcat
    20341 tcaattggta attaaattta gctgaacgaa gaatagcgcc atcttttgtt gctgtaaaaa
    20401 gaaaggaatt tctgcgaagc ataaatagaa ggttttctct gacaattaac agcggttcaa
    20461 tctgctgagc ccatcccttg atttttcttt caatgtacaa agttataatt aatccaacag
    20521 ataatgtaat catttggaga aaccatccct taaaaagaat actactagaa agggacaaca
    20581 tgctcaaaaa tcctatagta aaccagcgaa tacttctcaa tttagatgta tttaaaaagt
    20641 agtgctcaga caaagaagcc gtttgtttaa ttttaaacat tttttacctc attttatttc
    20701 tgagatcttt aattaaaaga aaaacagaga ataacttgac ccggataaaa tagtaaagga
    20761 atatggcaaa gaaaagaaat gctaggattg agaacagcac actaagtgca gaccccaccc
    20821 ctgtaggagt atacactgat agaagagcaa agacgaaaaa accaagaaag caaaatctat
    20881 atttatttat cattgttatt taccctctta atcatagctg gtagtatagc taataattga
    20941 actacaaaga ctatcaaagc tactactaat ccaaacttgg cggataagaa gggattatag
    21001 gaattgaagg acagttttcc tccaaatcca gcaaaaaagc tcataatggc caataatata
    21061 agacaactcg ttctccagaa atattcagta accttcattt ttttatattt tcctttcaat
    21121 ttttttcaaa acaaggactt ctcctcaata acaaattaag caatagcacc tgcaaggcac
    21181 ttaactagat aggaacgttt aacatgtttc cactctaacg cattaatata ataataaaac
    21241 aaatcgctat tatagtttag ttctttttct ataagggaaa tattactagg cgtagctttt
    21301 ctagcaatcg aacgatgatt ttttcgaatc tcctctagca aaccatcttt aatatatttt
    21361 gaggaattca tatttaaaaa gaatgaatct aaatgtattt gtttttcctc gttaagccac
    21421 tctaccaaag tttcccgtgt tgacttgtga actaacatat ttgctaataa gatagaatta
    21481 gccattttca tagaacaagg ataagtataa ggtaaacgta gaatctttcg cagatatgtt
    21541 tgtgagtctt tatcgaaaac aaaacctaaa ttatactcaa aatgaatgtt ctgcaatctc
    21601 aaagtttgct cattgcttct agggcactca taccctccgt caataaattt ttgtttgaat
    21661 gtttcagtat tcattattta atactccttt tttactcgtg aattattttt atcaacaatt
    21721 aacaattttt cttaataggt gaagctctag ctttcatctt catcctccaa tatatacatc
    21781 tttgattaac acacccaagc gttaaaaaat aagacaaaga gtttgtcatt gattaacaca
    21841 aaagaagcga aaaaatttag agagaaatct ctctaattaa agtatacttg aactcaacta
    21901 aaaagtcaat acttgattaa cacttttctt gaaatttttc tagtaaacct tttttcttta
    21961 aaatagaagc aaataaaact aacttcacta caaatgaaaa gaatactctc ccctttgtaa
    22021 gctctctcaa ccttaactgt atatctctca taccttcata tactaatgtg tctaaagtca
    22081 aagttgttct caagctagtg gcatctatat ctacgctttc actaatttca cttatcttaa
    22141 tttttgactt gttcaactct acccaatcaa taatatcaat ctcatttgat atctgtttgt
    22201 aagcaacttc aatcacatat ccatcagaaa cggggatatc tgaactgcct aaataaagcc
    22261 ttctaacttc cctcaatcct aaaacgctat ctctacttaa tttaatacct aatctttcat
    22321 tattcttcat ctattccccc caagtgttaa tctataatta actataccat attttaaatt
    22381 ctttttcaaa caataagtcg ggcaattgcc gggcaacgcc ccaccaacaa actcaaaaaa
    22441 ctcatttaaa cgttacaaaa caccagaaaa tcaagaacat ctaaacaaca tatctcctac
    22501 aattcctgta gggggcatat aaatacaaca ggaaaagtct tataatatag ggcttttttt
    22561 gcttaaataa aatttttttc aaattcttta gaaaactagt ttaaatcata atccaacacc
    22621 aattttacaa ataccataaa ctaagcttat atacccaaaa cacaaaaagt cctctttcca
    22681 ctattttaga aagagaactt tttctttagg agaaataact taatttttaa tcaattcgtg
    22741 atagctcagc tggcaccgtt aagtaataag ttgcagtcaa gcttgcttca ccttgattaa
    22801 caaaaatctc gatggaattt ttatctagaa caacttccaa ttctttagct tcaatatcta
    22861 cataccgtcg actagtgtcc tgttcttctt cacctagaat tttttgaata agatggctac
    22921 gatcaatgta aacttgctgc acattactgt cataaccaaa ttcaagataa tctgtatcat
    22981 ttcctaagtg gtaatgacaa tctttatcta tttggatttg atattggcct tttttaacag
    23041 ggaattgtct tagtttgcca tcttccaatc ttagaattct aggtaaagtc atggcacatg
    23101 cccacttgtg ttcttggtca tgggttggaa gggtacgccc ccatgtctgc atccaagcaa
    23161 tcaggatacg acgattttga tcgtccaaca atgtttgagg cgcatagaag tcttggccat
    23221 gatcaatttc ttgaactgat tctgggataa aacatttttc tccccaatct accttacccg
    23281 tgaacaaaag cgatgagttg atgttatgat atgagtctcc ctcacgctga taacgcatgg
    23341 gtgacataat aaggcaatct ttcccatcta actcgaagta atctgggcat tcccacataa
    23401 agccttggtg ttctacccct tttaaaaaga tggattcgaa ctgccattct actaggttat
    23461 cggaccctag tagaacgata cagcccacat tattcttgtg tttggcagct actacggagt
    23521 aatagcgtcc atctttttca aagagttttg gatcacggaa atcagcagca atcaactcat
    23581 ctggcaagtc tgatccagtt gcaactggat tttgggaaat cttttcaaag tgaatcccgt
    23641 catctgaaaa tgccatattt tgcacttggc ggacaccggt tttttcttcg atatgcccag
    23701 tgtacatgag ccagaggcga tcatccttga caatggcaga gcctgagaaa caaccatttc
    23761 ggtcataatc ttgatcagga gcaagtgcca ctggcaagtg ctcccaagtc accaagtcct
    23821 tacttttagc atgtccccag tgcataggcc cccaaacact atcatatgga tagaattgat
    23881 aaaagagatg gtattctcca cgaaaataga caaatccatt tggatcattg atccaaccaa
    23941 tctcagctga aaaatgttct tcaggcttat attgagtatt aacgagatgt ttattttctg
    24001 ctataaaacg attggctttt tctactgtaa atgttttatt tatcataagt atatcctatt
    24061 ttattccagt tccggaacca cccagacctt gaacaatata tttctgagcg actacataga
    24121 ccaaaatcaa cggaatcgtt gaaatagtta atacagccat tacctgattg atataaactg
    24181 gttgagttgt attaatagtt gtaattgcaa cctgcattga aaatttagaa gaatctgtca
    24241 aaaccatcaa tggccagata taatcattcc agcttgaaat aaatgataaa acaccaactg
    24301 tagcaactgc aggtttagac attggaagca taattctaaa gaaaattcta acgatacttg
    24361 ctccgtccat ctttgcagac tcaagaatct cttctggaat tgcaataaag aaattcctaa
    24421 ataagtaaat attaaataca ctcgccaatc ctggaataat aactgcaaga cgattattga
    24481 ccaaacctaa ggaattgata atggtaaatt gtggaattaa cacagtttcc actggaataa
    24541 taagtaaagc aagtaagaaa ccaaataaaa ttttcttacc tgaaaaattg acttttgcaa
    24601 aagcgaaacc ggccagtgca ttgacaataa tagaaccaat agcaaacgtt ccagcataaa
    24661 aaatgctgtt ccctagatat gtaaaaatac taaagcgctc aaatacttcc tgataaggtt
    24721 taaaccaatc agcgggattt aaacttggta agaaggcttg ccaactagtc aaatttttat
    24781 aaacatccgc ttctggcttc atagctgaaa ctaccatcca aaccatagga aaaaggaaga
    24841 gtcctgccaa taaagttaac agaatatatt ctaagattgt tgttggttta aatcgtttca
    24901 tcttagtcat cctccttcag aacgcgacgt tgtactaagc taatcatacc aattaacgtt
    24961 gtaaatacta aagcgattga gctagaatat cctacaagac gatcagtaaa accttgttga
    25021 taaatatagt acaccatagt aattgttgag tttaatggcc caccttgcgt cataaccatt
    25081 ggttgtacaa tcagcttaaa agcagaaatt aaagttgtta acaatacaaa cagggctgtt
    25141 ggttttagta ggggcatcgt gatataacga aactgagccc attttgagaa tccatctaat
    25201 tcagcagctt catagacatc ttgtggaata ttctgcattc ctcctaaaaa taaaagcatc
    25261 tgataacctg caccctgcca agcagaaaca aaaacaattg catacatagc ttgtttagga
    25321 ctagtcaaga aaggttgaga agcaatacct accttattta aaatagcatt taataagcca
    25381 ctatttggat ttaaaagata aagccaaaga atagaaataa ctaccaagga catgacaact
    25441 ggagcaaaaa aagccacttt aaaaaacata tttccttttc gctttttatt gacaatcaaa
    25501 gccattccta aggccgctcc caattgaact ggaataatcc aaacaacaaa tttcaaagta
    25561 ttcaagaagc tctttaagaa aatcggatct tttgttaatc gaataaaatt ttcaagtcca
    25621 acaaattttc tttcatctgg tgtcaacaaa taataatctg taaaagcgta ataaatgacc
    25681 attccaactg gaattactaa aaagatacct aataaaatta aagctggagc taaaaaacta
    25741 taacctaata tgttatcctt tattttttca cgtctttttg tatccacaac agtttcttta
    25801 ctcatatcca tctcctttaa tcatatatat caaactaggc tattaacaag aaaggggaag
    25861 gtagttccaa acattttcct tccaccttct tttttacaga ttatttgagt gactgatcaa
    25921 tagcagtttg catttctttt gtacgagtat ccaagacttt ttgcacattt ggattttctt
    25981 cataatagct aatatcttgc attgcttgtt gaaaagctcg agaaacctga ggatatgcta
    26041 caacaactgg gcgagcatga gctgtttttg aattttgttc catcaagaaa cgcattggtt
    26101 cggatacttt atctttgata ttttcaattg tagatttacg aattggaagg accgaattcc
    26161 ccaagctaat aatttcactt gattctgtat ttgtagcaaa tttaacaaat tcagatgcgg
    26221 cctctttttt atcagatttt gtcgtcacag ctaattgcca actacctgaa ggggatacta
    26281 attttttcgt cttactagat actgggtaag gaaggatacc aaaatcaata tctttgtagt
    26341 ttgtattcat gtcagcaatc gtccaagaac cactcaaaag cattggatac tctcctgttt
    26401 caaaaccttt ttcgactgga ctaacagttg tatagccttc ttttacaaga ttttgaatga
    26461 attgaactgc ttctacactc tctttggagt tgaagtatcc ttctgccttt gttccatctt
    26521 cgtttacgac agaaccatta tttgaccaaa tcaacggcat ataagcatat ggcaacattt
    26581 catcgtttga attaatacga aaatcaattg ttggtttgtt ataatgatct ttcaattttt
    26641 tagcaatcgt attaaattcg tcccatgtcc atggcttttc tagcgttgga agctctgatt
    26701 ccgcaattcc ggcctctttg aacatttttt tattgtaata aacaccaaca ttcgattcag
    26761 aaaatccaaa tgcatagaat ttcccattat aagttccctg ttgtttaata ctgtccaaaa
    26821 catcatccat attattatct tttagataat catctagcgg agtaattact ttagattttg
    26881 cataagctgc cgtatttggt ccatcaaggg taataacatc tggaagacta ttagtcgtaa
    26941 tagcagcatt aaccttgtct tcatatcctc caccactacc actacgagga atatactcag
    27001 ttacaacctt gtacttactt tttcctgatt gattaaagtt atcaacaact ttttgccaag
    27061 cttttccttc atttgtttcg tcagagaatt gtacccagac tttaatatca tttgaagaac
    27121 tcgcttgttt tgagttagtt cctccactac aacctgcaag tatagctaac gatagccccg
    27181 caacaacaga taacattgta cctttacgca tcattttcct cctttttgaa acgtttcatt
    27241 ttttatttat tttttaaaca agcttctagc ctatttttga aacgtttcat ttgttgatta
    27301 tattataaca gcgctttcat taattgtcaa gcgcttttta aatttttttt gttgttttat
    27361 ctccccaaaa atatgtggga attacgattc gtttttctag aatctcttct cgcttaatca
    27421 ttttcagtat cattgcaaca gattcttttg ccatcatacc aatatcttga actattgtag
    27481 acactagata agattgatcg acagaagttt ttaaaccatc aaacccaatt atctggtaat
    27541 catcaggtgc tattttcccc agttctttca taacactaat aactctcaga gccatcatat
    27601 catttattgt aaatatacca tcaatttctt tatgagattg caaaaaaatt cttatctgat
    27661 cttcaggatt tattaaaggt tctttcattt caaaattata gacatctact cctaattcct
    27721 tagctttttc tctgaatcct ttacttctga gtatagtctc attctcatac atattaattg
    27781 aaccaataaa agcaaggtgc ttattatccc ttctaaccag ttcctctgct gcagtttgtc
    27841 ctcctttgta atttgctgaa gtaacatagc atacattttc cgaaaaatgt ctatctatac
    27901 ttacaaacgg taaatcagat aaaatatatt tgtcaatatc agaatatgta ataccaataa
    27961 ttccatccac tttattttgt ttcaacattt cgatatattc gatttcattt tgtgaatcgc
    28021 tatcagcgtt acaaataaat aatttataat tatattttag taactctttc tcaacatgat
    28081 aggcaaactc cgaaaaaaat ggatgccata tgctcggaat aatcaaagcg atagtttctg
    28141 ttctattctt tttcatacct cgagcataat tatcagggat atagtccaat gtttttatag
    28201 ccctttgaac tttccttaaa gttacttctt taattccttt ttctttatta attacacgtg
    28261 aaacagttcc aacactaact cctgcttcta aagcaacatc tttcatggta attgattttc
    28321 tttgttctac catattatca cctcctttca atatatagta tcatgcaaat gctttttaag
    28381 caactatttc tcaatcattt ttggccagat catttatccc atcatgaata aaatcactcc
    28441 aattagcttt tgaaaatact tcaattttca tgtgtaaaca tctacataaa acaggaaaag
    28501 ccttggtttc atggcttttt tcgtatcttc tacaaaaaaa gcaagagttt tagagggcta
    28561 taaatctaga tgtacatttt tcttaaatga ttgaaggtct tttcttaaca aaaacaccct
    28621 aaaaattaga ctttttctgt ctaacttttg aggtacagtt caaacgcgaa atagcgtttt
    28681 tttgttattt ttggttactc atctaatcga ataaacatca tggcatttaa caagtatatg
    28741 agtgagaccg tgtttatatt atttgaatag atgagtctct tattttcaat aggaggaata
    28801 ataaaattag aaataatgat atcataagat gaatcttcta aagattcctt tgataattct
    28861 aattcagtcc aaacttccag ttcaaaatta ttgctacagt aataagaaag tgtctctgca
    28921 acgaattttg catgatactg atcaaaatta ctcataacta aaacctttag tttaggctga
    28981 ttttgtagca aattaatcac caaatgtttg gtatgagtga tgaaggtata agatagatga
    29041 tttaccatca ttgaactaga acaaacctca agagtctcta aatagtgaga aagctctttt
    29101 tttatatctg aaacaaattt tggaaaaata ttttgaaagt tcctgattgt attccctttt
    29161 tgatcaaata aaataaactc agtaaacaac tcttgacgat acagatgtgc ggtattatgc
    29221 agatgccaaa tcagattatc cctattctcc atttcaatct gatacttgac tgaaatctga
    29281 tcaataaaat cactcaatag atggtaagat ttttcaacat aactatcctt ttttacgcat
    29341 ttcataaaga gactttcatc tatgaaaaac attttttgaa agtaagacac aaataattgg
    29401 caaacaactt cttcatctaa agagatattg tattctgatt caaaactctg agcaacacct
    29461 tctattcctt ctgcctgcat taaaaaatcc aaactttggt cgttaaaaga atctttatct
    29521 acttccataa aatgaccaaa ctttattcta tataggttcg taactaggag caactttagc
    29581 attctatgcg ttgacaaatt cattggaaag cttgtttcct tataaaccaa ttctaacaat
    29641 tgagatagtg gctctgatga aaaattttca aatggccatt ctaggaaata atatttttct
    29701 gaaaaatatt gtgcaaaaaa gtaacgaatg tctctctcgt ttccaatgat ttgaacaggg
    29761 gtcagactga cttcaaattg aaattgcctt ttaatcactt tattgatttg gctaataata
    29821 cgatagagcg aagatgaact gatataaaat tctttacaaa tactctcagc ttgacaacct
    29881 tcattaaaga agatgaattc taaaatcgaa aaatgagttg aatgtttaaa gaaatgatgg
    29941 taaaccattt caatatcact atcatcggta ttaataatgc gtataccatt agtagaagaa
    30001 tgaaaaatca agtcaggaaa agcagattta acatgggata gatcatcttt gactgcacgt
    30061 tctgtacaat ttaataactc tgctagttca gaacgatgaa accaacgttt atgttcaaat
    30121 aataattcta ataattctaa ttgcctatga ctttttttag ataataaatc tctcatgaat
    30181 atctttctct ctttataaat tatcggatta aacctcttgc aattatacca caaagaatag
    30241 gtatagcatg atataacgac ttttcctaaa atcttttatt tcgtataata aca
//
LOCUS       DAVMAH010000027        30276 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVMAH010000027 DAVMAH010000000
VERSION     DAVMAH010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30276
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.027"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            699..1691
                     /locus_tag="VYO94_001131"
     CDS             699..1691
                     /locus_tag="VYO94_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1759776.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1693..2511
                     /locus_tag="VYO94_001132"
     CDS             1693..2511
                     /locus_tag="VYO94_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV1759777.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2513..3298
                     /locus_tag="VYO94_001133"
     CDS             2513..3298
                     /locus_tag="VYO94_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1759778.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3337..3615
                     /locus_tag="VYO94_001134"
     CDS             3337..3615
                     /locus_tag="VYO94_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV1759779.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3600..3797
                     /locus_tag="VYO94_001135"
     CDS             3600..3797
                     /locus_tag="VYO94_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1759780.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(4223..4315)
                     /locus_tag="VYO94_001136"
                     /pseudo
     CDS             complement(4223..4315)
                     /locus_tag="VYO94_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4529..10948
                     /locus_tag="VYO94_001137"
     CDS             4529..10948
                     /locus_tag="VYO94_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV1759781.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKEENSNK
                     SQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGSKAIKELSSLKNTKVLYTYDRIF
                     NGGAIETTQDNLNKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHF
                     IRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSF
                     TIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAYEDES
                     ALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEIKATK
                     YDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAETKIRMPEKNKETKAEY
                     PYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKV
                     TTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLM
                     SALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEA
                     IKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVN
                     ESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYL
                     QTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFD
                     GEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSE
                     LKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYV
                     INLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDH
                     SQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLG
                     LKKKNQD"
     gene            11575..12051
                     /locus_tag="VYO94_001138"
     CDS             11575..12051
                     /locus_tag="VYO94_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1759782.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAETTA"
     gene            12089..12394
                     /locus_tag="VYO94_001139"
     CDS             12089..12394
                     /locus_tag="VYO94_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1759783.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            12442..13917
                     /locus_tag="VYO94_001140"
     CDS             12442..13917
                     /locus_tag="VYO94_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV1759784.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            14267..20968
                     /locus_tag="VYO94_001141"
     CDS             14267..20968
                     /locus_tag="VYO94_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV1759785.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLNEDAKAVTNEEVNQMIENRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLYKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQYGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGFWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSL
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTNLNSVDKFVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLRFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQENLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKTQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(21216..22072)
                     /locus_tag="VYO94_001142"
                     /pseudo
     CDS             complement(21216..22072)
                     /locus_tag="VYO94_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(22282..22641)
                     /locus_tag="VYO94_001143"
     CDS             complement(22282..22641)
                     /locus_tag="VYO94_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV1759786.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            22733..23689
                     /locus_tag="VYO94_001144"
                     /pseudo
     CDS             22733..23689
                     /locus_tag="VYO94_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            23673..24230
                     /locus_tag="VYO94_001145"
     CDS             23673..24230
                     /locus_tag="VYO94_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1759787.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            24223..24477
                     /locus_tag="VYO94_001146"
     CDS             24223..24477
                     /locus_tag="VYO94_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759788.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            24489..26543
                     /locus_tag="VYO94_001147"
     CDS             24489..26543
                     /locus_tag="VYO94_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV1759789.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIVLTFVFFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            26722..27582
                     /locus_tag="VYO94_001148"
     CDS             26722..27582
                     /locus_tag="VYO94_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV1759790.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            27801..28511
                     /gene="ccdA2"
                     /locus_tag="VYO94_001149"
     CDS             27801..28511
                     /gene="ccdA2"
                     /locus_tag="VYO94_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1759791.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            28531..29097
                     /locus_tag="VYO94_001150"
     CDS             28531..29097
                     /locus_tag="VYO94_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV1759792.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            29108..30220
                     /gene="msrB"
                     /locus_tag="VYO94_001151"
     CDS             29108..30220
                     /gene="msrB"
                     /locus_tag="VYO94_001151"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1759793.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         9716 a         5276 c         6397 g         8887 t
ORIGIN      
        1 tcttcatcag aatgataaaa ttaatcaatt gatatctgat tacaaacaga atatgaaagc
       61 tttttatatc actattgaaa aatttatacg agatgatgaa agccttaagt gttattttat
      121 aaaggttatt tcaagtcgtt ccaaggtaac aagtctagat cagattgaag ctgataaaac
      181 gatacaaaga aaatattcaa gtgagctaaa aaaatttatt ggattttata atgagattat
      241 ttgtgaggaa aatagtttcc tacatgtacg aaagaggtgg tcgagttggt ttaggtagtc
      301 gatgcgtgag ttgataattc tcagggtatg gacttctttt tcatgaatga ggtaaaagag
      361 caggtattgt ttagagacaa tcattctgag catattttct ggatagaggg agtatccgat
      421 tttatgatca aagttaatac cgccctctgg tgagaagatg agtaggttgg taatttaaac
      481 tattaaacag aatttttgat taaaagtatt atttcatgag agaaatccta atttcacaat
      541 ccataggcaa acgcttgcat ttcgtttttt attggactat aataggttgg tataaagcct
      601 tctgtagtaa taaaatgtag aaggtgtaga aagtaaggat ttagaatatt tgtagttaaa
      661 aacacaatgt tgctattcct tacgataggg agatagatat ggcaatgata gaagtggaac
      721 atcttcagaa aaattttgtg aagactgtta aggaaccggg cttgaagggg gctttgcgct
      781 cctttattca tcctgaaaag cagacctttg aagcggtcaa ggatttgacc tttgaggttc
      841 caaaagggca gattttagga tttatcgggg caaatggtgc tgggaagtcg acaaccatta
      901 aaatgctgac aggaattttg aaaccaacat ctggtttttg tcggattaac ggcaagattc
      961 cccaggacaa tcggcaagat tatgtcaaag atattggcgt agtctttgga caacgcaccc
     1021 agctatggtg ggatttggct ctgcaagaga cctacactgt cttaaaagag atttatgatg
     1081 tgccagactc gctctttcat aagcgtatgg actttttgaa tgaagtcttg gatttgaagg
     1141 actttatcaa ggatcccgtg cggactcttt cactgggaca acggatgcgg gcggatattg
     1201 cggcctcctt gctccacaat cccaaggttc tttttttaga tgagccgacc attggtttgg
     1261 acgtttcggt taaggataat attcgtcggg caattactca gatcaatcaa gaggaagaaa
     1321 ctaccattct tttgaccact cacgatttga gtgatattga gcaactttgt gatcggattt
     1381 tcatgattga caaggggcaa gagatttttg atggaacggt gagccaactc aaggagacct
     1441 ttggtaagat gaagactctc tcttttgaac tgctaccagg tcaaagtcat ctcgtctctc
     1501 actatgacgg tctgtctgat atgaccattg atagacaagg aaacagcctc aacattgaat
     1561 ttgatagttc tcgctaccag tcagctgaca ttatcaagca aaccctgtct gattttgaaa
     1621 tccgcgattt gaagatggtg gatacggata ttgaggatat tatccgtcgc ttctaccgaa
     1681 aggagctcta ggatgatcaa attgtggaga cgttataaac cctttatcaa tgcaggggtt
     1741 caggagttga ttacttaccg agtcaacttt attctctatc ggattggcga tgtcatgggg
     1801 gcttttgtgg ccttttatct ctggaaggct gtctttgatt cttcgcaaga gtctttgatt
     1861 cagggcttca gtatggcgga tatcaccctc tacatcatca tgagttttgt gaccaatctt
     1921 ctgactagat ccgattcgtc ctttatgatt ggggaggagg tcaaggatgg ctccattatc
     1981 atgcgtttgt tgcgaccagt gcattttgcg gcctcctatc ttttcaccga gcttggttcc
     2041 aagtggttga tttttatcag cgttggcctt ccatttttaa gtgtcattgt cttgatgaaa
     2101 atcatatcgg gtcaaggtat tgtagaggtg ctaggattaa ctgtcattta tctttttagc
     2161 ttaacgctcg cctatctgat taactttttc tttaatattt gctttggatt ttcagccttt
     2221 gtgtttaaaa atctttgggg ttccaaccta cttaagactt ccatagtggc ttttatgtcg
     2281 gggagtttga ttcccttggc attttttcca aaggttgttt cagatattct ctcctttttg
     2341 cctttttcat ccttgattta tactccagtt atgatcattg ttggaaaata cgatgccagt
     2401 cagattcttc aggcactcct tttgcagttc ttctggctct tagtgatggt gggattgtct
     2461 cagttaattt ggaaacgggt ccagtccttt atcaccattc aaggaggtta gtatgaaaaa
     2521 atatcaacga atgcatctga tttttatcag acaatacatc aaacaaatca tggaatataa
     2581 ggtagatttt gtggttggtg tcttgggagt ctttctgact caaggcttga atctcttgtt
     2641 tctcaatgtc atctttcaac atattccatt cctagaaggc tggacctttc aagagatagc
     2701 tttcatttat ggattttcct tgattcccaa gggaatggac catctctttt ttgacaatct
     2761 ctgggcacta gggcaacgcc tagtccgaaa aggggagttt gacaagtatc tgactcgtcc
     2821 catcaatcct ctctttcaca tcctagttga aacctttcag attgatgcct tgggtgaact
     2881 cttagtcggt ggtattttat tgggaacaac agtgaccagc attgtttgga ctcttccaaa
     2941 attcctgctt ttcctagttt gtattccttt tgcgaccttg atttatactt ctcttaaaat
     3001 cgcaacagcc agtatcgcct tttggactaa gcagtcaggc gccatgattt acatcttcta
     3061 tatgttcaat gactttgcta agtatccgat ttctatttac aattctcttc ttcgttggtt
     3121 gattagcttt atcgtgcctt tcgcctttac agcctactat ccagctagct atttcttaca
     3181 ggaaaaggat gtgttcttta acgtaggagg tttgatgttg atttctctgg ttttctttgt
     3241 tatttccctt aaactttggg ataagggctt agattcctac gaaagtgcgg gttcgtaaaa
     3301 gctaaagtaa gactaaaatc aagaaagaaa cttatgatgt ttgtaattga agaagtcaag
     3361 gatgaaaatc aaaaaaaggc agttgtcgct gaggttttga aggatttgcc agaatggttt
     3421 ggaatcccag aaagcacaca agcctatata gaaggaacca cgacactgca agtttggacc
     3481 gcctatcagg agagtgattt gactagattt gtaagcttat cctattcgag tgaagattgt
     3541 gcagagattg attgtctcgg cgtaaaaaag cttatcaagg tagaaaaatt gggagccaat
     3601 tgcttgctac tttagagagt gaagctcgta aaaaagttgg ttatctgcag gtcaaaacag
     3661 tggcagaagg ttctaataaa gattatgatc gaacaaatga cttttatcga ggtcttggct
     3721 ttaaaaagtt agagattttt cctcaactat ggaatccgca aaatccttgt cagattttga
     3781 ttaaaaagct tgaataatat tacttgacat ctattctcag agtgctatac tgtaagtgta
     3841 atcgccgatt tagcttagtt ggtagagcaa ggcactcgta aagcctaggt tataggtaga
     3901 taaacgactg aggatttgaa aaaatagata ggtagaagat aaccgttaag ccttactctt
     3961 agcggttatt tatattgttt aatagcgcta atattttatc aattatgcct gttttcgtgt
     4021 ttctggtagt tgttcaagtt tattgctact atttttgatg gtatgaatgt gcttataatg
     4081 tatcccggtt aacgaaagtt ttggacttat actcttcgaa aatctcttca aaccacgtca
     4141 acgtcgcctt gccgtgcgta tggttactga cttcgtcagt tctatccaca acctcaaaac
     4201 agtgttttga gctgactacg tcagttccat ctacaacctc aaaacactgt tttgagcaat
     4261 ctgcggctag tttcctagtt tgctctttga ttttcattga gtactaatct tattttttaa
     4321 tgtgtgctaa aaaataaatt aactaatgtt aatttttttg acttaaattt ttttaaatga
     4381 tatactgttt ttatagagag ataacaatta tatataaatg tactactcta tttcctagat
     4441 aatacttagt aaaacttttt ataacaaagg ctagcaaagt taaagtttat tatctattgg
     4501 aagttatata aatatgtaag gaattaaaat gaaaaaaagt acagtattgt cattaaccac
     4561 agctgcagtt attttagcag cctatgcccc taatgaggta gtcttagcag acacatctag
     4621 ctctgaagat gctttaagca tctctgataa agaaaaagta gcagaaaata aagagaaaca
     4681 taaagatatt cataatgcta tagaaacttc aaaggatact gaagaaaaga aaacaacaat
     4741 tattgaggaa aaagaagttg ttagtaaaaa tcctgtgata gacactaaaa ctagcaatga
     4801 agaagcaaaa atcaaagaag aaaattccaa taaatcccaa ggagatcata cggactcatt
     4861 tgtgaataaa aacacagaaa atcccaaaaa agaagataaa gttgtctata ttgctgaatt
     4921 taaagataag gaatctggat caaaagcaat caaggaacta tccagtctta agaatacaaa
     4981 agttttatat acttatgata gaatttttaa cggtggtgct attgaaacaa ctcaagataa
     5041 tctgaataaa attaaacaaa tagaaggtat tacatcggtt gaaagggcac aaaaagtcca
     5101 acccatgatg aatcatgcca gaaaggaaat tggagttgag gaagctattg attacctaaa
     5161 gtctatcaat gctccgtttg ggaaaaattt tgatggtaga ggtatggtca tttcaaatat
     5221 cgatactgga acagattata ggcataaggc tatgagaatc gatgatgatg ccaaagcctc
     5281 aatgagattt aaaaaagaag acttaaaagg aactgataaa aattattggt tgagtgataa
     5341 aatccctcat gcgttcaatt attataatgg tggcaaaatc actgtagaaa aatatgatga
     5401 tggaagggat tattttgacc cacatgggat gcatattgca gggattcttg ctggaaatga
     5461 tactgaacaa gatatcaaaa actttaacgg catagatgga attgcaccta atgcacaaat
     5521 tttctcttac aaaatgtatt ctgacgcagg atctgggttt gcgggtgatg aaacaatgtt
     5581 tcatgctatt gaagattcta tcaaacacaa cgttgatgtt gtttcggtat catctggttt
     5641 tacaggaaca ggtcttgtag gtgagaaata ttggcaagct attagggcat taagaaaagc
     5701 aggcattcca atggttgtcg ctacgggtaa ctatgcgact tctgcttcaa gttcttcatg
     5761 ggatttagta gcaaataatc atctgaaaat gaccgacact ggaaatgtaa cacgaactgc
     5821 agcacatgaa gatgcgatag cggtcgcttc tgctaaaaat caaacagttg agtttgataa
     5881 agttaacata ggtggagaaa gttttaaata cagaaatata ggggcctttt tcgataagaa
     5941 taaaatcaca acaaatgaag atggaacaaa agctcctagt aaattaaaat ttgtatatat
     6001 aggcaagggg caagaccaag atttgatagg tttggatctt aggggcaaaa ttgcagtaat
     6061 ggatagaatt tatacaaagg atttaaaaaa tgcttttaaa aaagctatgg ataagggtgc
     6121 acgcgccatt atggttgtaa atactgtaaa ttactacaat agagataatt ggacagagct
     6181 tccagctatg ggatatgaag cggatgaagg tactaaaagt caagtgtttt caatttcagg
     6241 agatgatggt gtaaagctat ggaacatgat taatcctaat aaaaaaactg aagtcaaaag
     6301 aaataataaa gaagatttta aagataaatt ggagcaatac tatccaattg atatggaaag
     6361 ttttaattcc aacaaaccga atgtaggtga cgaaaaagag attgacttta agtttgcacc
     6421 tgacacagac aaagaacttt ataaagaaga tatcatcgtt ccagcaggat ctacatcttg
     6481 ggggccaaga atagatttac ttttaaaacc cgatgtttca gcacctggta aaaatattaa
     6541 atccacgctt aatgttatta atggcaaatc aacttatggc tatatgtcag gaactagtat
     6601 ggcgactcca atcgtggcag cttctactgt tttgattaga cctaaattaa aggaaatgct
     6661 tgaaagacct gtattgaaaa atcttaaggg agatgacaaa atagatctta caagtcttac
     6721 aaaaattgcc ctacaaaata ctgcgcgacc tatgatggat gcaacttctt ggaaagaaaa
     6781 aagtcaatac tttgcatcac ctagacaaca gggagcaggc ctaattaatg tggccaatgc
     6841 tttgagaaat gaagttgtag caactttcaa aaacactgat tctaaaggtt tggtaaactc
     6901 atatggttcc atttctctta aagaaataaa aggtgataaa aaatacttta caatcaagct
     6961 tcacaataca tcaaacagac ctttgacttt taaagtttca gcatcagcga taactacaga
     7021 ttctctaact gacagattaa aacttgatga aacatataaa gatgaaaaat ctccagatgg
     7081 taagcaaatt gttccagaaa ttcacccaga aaaagtcaaa ggagcaaata tcacatttga
     7141 gcatgatact ttcactatag gcgcaaattc tagctttgat ttgaatgcgg ttataaatgt
     7201 tggagaggcc aaaaacaaaa ataaatttgt agaatcattt attcattttg agtcagtgga
     7261 agaaatggaa gctctaaact ccaacgggaa gaaaataaac ttccaacctt ctttgtcgat
     7321 gcctctaatg ggatttgctg ggaattggaa ccacgaacca atccttgata aatgggcttg
     7381 ggaagaaggg tcaagatcaa aaacactggg aggttatgat gatgatggta aaccgaaaat
     7441 tccaggaacc ttaaataagg gaattggtgg agaacatggt atagataaat ttaatccagc
     7501 aggagttata caaaatagaa aagataaaaa tacaacatcc ctggatcaaa atccagaatt
     7561 atttgctttc aataaccaag ggatcaacgc tccatcatca agtggttcta agattgctaa
     7621 catttatcct ttagattcaa atggaaatcc tcaagatgct caacttgaaa gaggattaac
     7681 accttctcca cttgtattaa gaagtgcaga agaaggattg atttcaatag taaatacaaa
     7741 taaagaggga gaaaatcaaa gagacttaaa agtcatttcg agagaacact ttattagagg
     7801 aattttaaat tctaaaagca atgatgcaaa gggaatcaaa tcatctaaac taaaagtttg
     7861 gggtgacttg aagtgggatg gactcatcta taatcctaga ggtagagaag aaaatgcacc
     7921 agaaagtaag gataatcaag atcctgctac taagataaga ggtcaatttg aaccgattgc
     7981 agaaggtcaa tatttctata aatttaaata tagattaact aaagattacc catggcaggt
     8041 ttcctatatt cctgtaaaaa ttgataacac cgcccctaag attgtttcgg ttgatttttc
     8101 aaatcctgaa aaaattaagt tgattacaaa ggatacttat cataaggtaa aagatcagta
     8161 taagaatgaa acgctatttg cgagagatca aaaagaacat cctgaaaaat ttgacgagat
     8221 tgcgaacgaa gtttggtatg ctggcgccgc tcttgttaat gaagatggag aggttgaaaa
     8281 aaatcttgaa gtaacttacg caggtgaggg tcaaggaaga aatagaaaac ttgacaaaga
     8341 cggaaatacc atttatgaaa ttaaaggtgc gggagattta aggggaaaaa tcattgaagt
     8401 cattgcatta gatggttcta gcaatttcac aaagattcat agaattaaat ttgctaatca
     8461 ggctgatgaa aaggggatga tttcctatta tctagtagat cctgatcaag attcatctaa
     8521 atatcaaaag cttggcgaga ttgcagaatc taaatttaaa aatttaggaa atggaaaaga
     8581 gggtagtcta aaaaaagata caactggggt agaacatcat catcaagaaa atgaagagtc
     8641 tattaaagaa aaatctagtt ttactattga tagaaatatt tcaacaatta gagactttga
     8701 aaataaagac ctaaagaaac tcattaaaaa gaaatataag gaagaagacg actttgtaac
     8761 tggtggaaaa agaacagtag aacttgatta taaatatgac gataaaggaa atataactgc
     8821 ctatgaagat gaaagtgctc tagaatatga aactgaaaaa tttgacgaaa taaaatcaaa
     8881 aatttatggt gttctaagcc catctaaaga tggacacttt gaaattcttg gaaagataag
     8941 caatgtttct aaaaatgcca aggtatatta tggaaataac tataaattta tagaaatcaa
     9001 agcgactaag tatgactcac attcaaaaac gatgacattt gatttatacg ctaatattaa
     9061 tgatattgtg gatggattag cttttgctgg agatatgcgg ttttttgtta aagatgatga
     9121 tcgaataaaa gctgaaacta aaattagaat gcctgaaaaa aataaggaaa ctaaagcaga
     9181 atatccctat gtatcaagtt atgggaatgt aatcgaatta ggagaaggag atctttcaaa
     9241 gaacaaacca gacaatttaa ctaaaatgga atctggtaaa atctattctg attcagaaaa
     9301 acaacaatat ctgttaaagg ataacatcat tctaagaaaa ggctatgcac taaaagtgac
     9361 tacctataat cctggaaaaa cggatatgtt agaagggaat ggagtctata gcaaggaaga
     9421 tatagcaaaa atacaaaagg ccaatcctaa tctaagagtc ctttcagaaa caacaattta
     9481 tgctgatagt agaaatgttg aagatggaag aagtacccaa gctgtattaa tgtcggcttt
     9541 ggacggcttt aacattataa ggtatcaagt gtttacattt aaaatgaacg ataaagggga
     9601 agctatcgat aaagacggaa atcttgtgac agattcttct aaacttgtat tatttggtaa
     9661 ggatgataaa gaatacactg gagaggataa gtccaatgta gaagctataa aagaagatgg
     9721 ctccatgtta tttattgata ccaaaccagt aaacctttca atggataaga actactttaa
     9781 tccatctaaa tctaataaaa tttatgtacg aaatccagaa ttttatttaa gaggtaagat
     9841 ttctgataag ggtggtttta actgggaatt gagagttaat gaatcggttg tagataatta
     9901 tttaatctac ggagatttac acattgataa cactagagat tttaatatta agttgaatgt
     9961 taaagacggt gacatcatgg actggggaat gaaagactat aaagcaaacg gatttccaga
    10021 taaggtaaca gatatggatg gaaatgttta tcttcaaact ggctatagcg atttgaatgc
    10081 taaagcagtt ggagtccact atcagttttt atatgataat gttaaacccg aagtaaacat
    10141 tgatcctaag ggaaatacta gtatcgaata tgctgatgga aaatctgtag tctttaacat
    10201 caatgataaa agaaataatg gattcgatgg tgagattcaa gaacaacata tttatgtaaa
    10261 tggaaaagaa tatacatcat ttgatgatat taaacaaata acagacaaga cactaaacat
    10321 taagattgtt gtaaaagatt ttgcaagaaa tacaaccgta aaagaattca ttttaaataa
    10381 agatacggga gaggtaagtg aattaaaacc tcatagggta actgtgacca ttcaaaatgg
    10441 aaaagaaatg agttcaacga tagtgtcgga agaagatttt attttacctg tttataaggg
    10501 tgaattagaa aaaggatacc aatttgatgg ttgggaaatt tctggtttcg aaggtaaaaa
    10561 agacgctggc tatgttatta atctatcaaa agataccttt ataaaacctg tattcaagaa
    10621 aatagaggag aaaaaggagg aagaaaataa acctactttt gatgtatcga aaaagaaaga
    10681 taacccacaa gtaaaccata gtcaattaaa tgaaagtcac agaaaagagg atttacaaag
    10741 agaagatcat tcacaaaaat ctgattcaac taaggatgtt acagctacag ttcttgataa
    10801 aaacaatatc agtagtaaat caactactaa caatcctaat aagttgccaa aaactggaac
    10861 agcaagcgga gcccagacac tattagctgc cggaataatg tttatagtag gaatttttct
    10921 tggattgaag aaaaaaaatc aagattaaga taaaagctat agaaaaaaat ggtttatgta
    10981 ctgagattag atagtgaggt gatgacatag ttttgtgaaa acagccattt ataactcaat
    11041 tatttagttt acttcactat tgatactatt tggagttatt aatggactta gtttagataa
    11101 ctaatgaatt gattgaaagg gttagtattg acaatattgg tcatattgat tagaaaatag
    11161 agtctatcaa aatttaaagg ctaatagagg tgatgagaca atttcaagga attaagtagc
    11221 gtttggttgc ttaattcctt tttatttgga aggaagtttt tcgtaaccgc ccaataacga
    11281 agtctattgg acggttacga tatgatcact gacttcgtca gtcttatcta caacctcaaa
    11341 actgtgtttt gagcaacctg cggctagctt cctagtttac tctttgattt tcattgagta
    11401 ttagaacaga aaaaatgctt ggagtatttg tttgtgtgtt tatttttata taacaaacta
    11461 taaacaaaac aaaaatataa aaaaagagac aaaaaagaac agaaagtaat tgacaacggt
    11521 tttatatagt gttatactta tggcataaag ttaatggaaa gaagggaaaa acttatggta
    11581 ttagattatt tctttgacaa aaaccttgtg ttttgcttag aagcggataa tcaagaacaa
    11641 ctctttgatc aggttgcaac tttattggaa gaacgagaaa ttgtcactcc aacttatcgt
    11701 gaagctttga tcacgcgtga aaagtcattt ccaactggtt tagatatgga atttctagga
    11761 aaggacttgc caaatgtagc gattcctcat acagatattg ttcataatct agctgagaaa
    11821 gtggtggttg ttcgattaga aaaaccagta acttttcaca atatgatagc tcctgataag
    11881 gaagtagaag tatccttgct cttctttatc atcaataact caagttcaag tcaaacaaat
    11941 attctggctc agttgatgga ctttttcaca ggaaatggac atcttgaaga cctatcaaaa
    12001 atttccgaac cagaaaaact ttatgcttac attgctgaaa caaccgctta atcttgtcta
    12061 ttaaaaaata aaatcggagg aaatctaaat gattaaaatt cttgctgcct gcggtgcagg
    12121 tgttaactca agtcaccaaa ttaaaagtgc tctagaagaa gaactttcaa accgtggtta
    12181 tgatgttcac tgtgatgcag tcatggtgaa agatgtaaac gaagacctta tgaaaggtta
    12241 cgatatcttt acaccaatcg ctgcaacaga ccttggtttt gaaccaggta tcccagttat
    12301 cgaagctgga ccaatcttat tccgtatccc agcaatgagc gctccagtat ttgacaatat
    12361 tgaagcagct attaaagaac acggattaag ctaattctaa tttgttaaca ttcatataac
    12421 ataaaaaagg gaggaactgt tatggatgca atctttgacc taatcggaaa ggttttcaat
    12481 cccatcttag aaatgggtgg acctgtcatc atgttaatca ttttgacagt attggcttta
    12541 ctttttggag tgaaattctc caaagcgctt gaaggtggta tcaaacttgc catcgctctt
    12601 acaggtatcg gtgctatcat cggtatgcta aatggtgctt tctcagcatc acttgcaaaa
    12661 ttcgttgaaa acactggtat ccaattgagt attaccgacg ttggttgggc accacttgca
    12721 acaatcactt ggggttctgc ttggacactt tacttcttgc tcatcatgtt gattgtcaac
    12781 gtagtgatgc ttgctatgaa gaaaaccgat acacttgatg tcgatatctt tgatatctgg
    12841 cacttgtcta tcacaggtct cttgattaaa tggtatgctg ataacaatgg tgtgagtcaa
    12901 ggggtttcac tcttgattgc tacagcagct atcgttcttg tcggtgtgtt gaaaattatc
    12961 aactctgact tgatgaaacc tacatttgat gaccttctta acgccccaag ttcatcacca
    13021 atgacatcaa ctcacatgaa ctacatgatg aacccagtta tcatggtttt ggataagatt
    13081 tttgaaaaat tcttcccagg ccttgataaa tatgactttg atgctgctaa attgaacaag
    13141 aaaatcggtt tctggggatc taaattcttc atcggtttca tccttggtat cgttatcggt
    13201 attatgggaa ctccacatcc aattgcaggt gttgcagatg cagataaatg gcgtcttgtt
    13261 atcaaaggat ggttgtctct tggtttgact gccggtgtat ctttggaact cttctcactt
    13321 atcggttcat ggttcatcgc agccgtagaa ccactatcac aaggtattac aaacgttgct
    13381 actaaacgtc ttcaaggacg taaattcaat atcggtcttg actggccatt catcgctggt
    13441 cgtgctgaaa tctgggcttg tgccaacgta cttgcaccaa tcatgttgat tgaagcagta
    13501 cttctttcaa aagttggaaa tggtatcttg ccacttgcag gtatcatcgc tatgggtgtt
    13561 actccagctc tcttggttgt aactcgtggt aaattgctcc gtatgattat cttcggaaca
    13621 ctcttgttgc cactcttcct tctttcaggt acacttattg caccatttgc aacagaactt
    13681 gctaaaggtg taggtgcctt cccagaaggt gtgagccaaa ctcaattgat tactcactct
    13741 actcttgaag gaccaatcga aaaacttctt ggttggacaa ttggtaacac tacaactggt
    13801 gatatcaaag caatccttgg tgcagtagcc ttccttgtat tctatatcgg tatctttgct
    13861 tggtacagaa aacaaatgat caaacgtaac gaagagtacg cagcaaaagc aaaataatgc
    13921 gctcctataa aatataaact caatgaaaat caaagagcaa actaggaagc tagccgcagg
    13981 ttgctaaaaa cacagttttg aggttgtaga taagactgac gaagtcagct caaaacatgg
    14041 ttttgaggtt gtagatgaaa ctgacgaagt cagctcaaaa catggttttg aggttgtaga
    14101 tgaaactgac gaagtcagta atcatatcta cggcaaggcg acactgacga agtttgaatt
    14161 ggattttcgc agagtgtaaa ttgttgaaac taggttgtca taccatgtat accacttggg
    14221 ctttagtagt agctaactgc actaaatata atataaggag ggttttatgg ggaaaggcca
    14281 ttggaatcgg aaaagagttt atagcattcg taagtttgct gtgggagctt gctcagtaat
    14341 gattgggact tgtgcagttc tattaggagg aaatatagct ggagaatctg tagtttatgc
    14401 ggatgaaaca cttattactc atactgctga gaaacctaaa gaggaaaaaa tgatagtaga
    14461 agaaaaggct gataaagctt tggaaactaa aaatgtagtt gaaaggacag aacaaagtga
    14521 acctagttca actgaggcta ttgcatctga gaagaaagaa gatgaagccg taactccaaa
    14581 agaggaaaaa gtgtctgcta aaccggaaga aaaagctcca aggatagaat cacaagcttc
    14641 aagtcaagaa aaaccgctca atgaagatgc taaagctgta acaaatgaag aagtgaatca
    14701 aatgattgaa aacaggaaag tggattttaa tcaaaattgg tactttaaac tcaatgcaaa
    14761 ttctaaggaa gccattaaac ctgatgcaga cgtatctacg tggaaaaaat tagatttacc
    14821 gtatgactgg agtatcttta acgatttcga tcatgaatct cctgcacaaa atgaaggtgg
    14881 acagctcaac ggtggggaag cttggtatcg caagactttc aaactagatg aaaaagacct
    14941 caagaaaaat gttcgcctta cttttgatgg cgtctacatg gattctcaag tttatgtcaa
    15001 tggtcagtta gtggggcatt atccaaatgg ttataaccag ttctcatacg atatcaccaa
    15061 atacctttac aaagatggtc gtgagaatgt gattgctgtc catgcagtca acaaacagcc
    15121 aagtagccgt tggtattcag gaagtggtat ctatcgtgat gtgactttac aagtgacaga
    15181 taaggtgcat gttgagaaaa atgggacaac tattttaaca ccaaaacttg aagaacaaca
    15241 atatggcaag gttgaaactc atgtgaccag caaaatcgtc aatacggacg acaaagacca
    15301 tgaacttgta gccgaatatc aaatcgttga acgaggtggt catgctgtaa caggcttagt
    15361 tcgtacagcg agtcgtacct taaaagcaca tgaatcaaca agcctagatg cgattttaga
    15421 agttgaaaga ccaaaactct ggaccgtttt aaatgacaaa cctgccttgt acgaattgat
    15481 tacgcgtgtt taccgtgacg gtcaattggt tgatgctaag aaggatttgt ttggttaccg
    15541 ttactatcac tggactccaa atgaaggttt ctctttgaat ggtgaacgta ttaaattcca
    15601 tggagtatcc ttgcaccacg accatggggc gcttggagca gaagaaaact ataaagcaga
    15661 atatcgccgt ctcaaacaaa tgaaggagat gggagttaac tccatccgta caacccacaa
    15721 ccctgctagt gagcaaacct tgcaaatcgc agcagaacta ggtttactcg ttcaggaaga
    15781 ggcctttgat acttggtatg gtggcaagaa accttatgac tatggacgtt tctttgaaaa
    15841 agatgccact cacccagaag ctcgaaaagg tgaaaaatgg tctgattttg acctacgtac
    15901 catggtcgaa agaggcaaaa acaaccctgc tatcttcatg tggtcaattg gtaatgaaat
    15961 aggtgaagct aatggtgatg cccactcttt agcaactgtt aaacgtttgg tcaaggttat
    16021 caaggatgtt gataagactc gctatgttac catgggagca gataaattcc gtttcggtaa
    16081 tggtagcgga gggcatgaga aaattgctga tgaactcgat gctgttggat ttaactattc
    16141 tgaagataat tacaaagccc ttagagctaa gcatccaaaa tggttgattt acggttcaga
    16201 aacatcatca gcaacccgta cacgaggaag ttactatcgc cctgaacgtg aattgaaaca
    16261 tagcaatgga cctgagcgta attatgaaca gtcagattat ggaaatgatc gtgtgggttg
    16321 ggggaaaaca gcaaccgctt catggacttt tgaccgtgac aacgctggct atgctggaca
    16381 gtttatctgg acaggtacgg actatattgg tgaacctaca ccatggcaca accaaaatca
    16441 aactcctgtt aagagctctt actttggtat cgtagataca gccggcattc caaaacatga
    16501 cttctatctc taccaaagcc aatgggtttc tgttaagaag aaaccgatgg tacaccttct
    16561 tcctcactgg aactgggaaa acaaagaatt agcatccaaa gtagctgact cagaaggtaa
    16621 gattccagtt cgtgcttatt cgaatgcttc tagtgtagaa ttattcttga atggaaaatc
    16681 tcttggtctt aagactttca ataaaaaaca aaccagcgat gggcggactt accaagaagg
    16741 tgcaaatgct aatgaacttt atcttgaatg gaaagttgcc tatcaaccag gtaccttgga
    16801 agcaattgct cgtgatgaat ctggcaagga aattgctcga gataagatta cgactgctgg
    16861 taagccagcg gcagttcgtc ttattaagga agaccatgcg attgcagcag atggaaaaga
    16921 cttgacttac atctactatg aaattgttga cagccagggg aatgtggttc caactgctaa
    16981 taatctggtt cgcttccaat tgcatggcca aggtcaactg gtcggtgtag ataacggaga
    17041 acaagccagc cgtgaacgct ataaggcgca agcagatggt ttttggattc gtaaagcatt
    17101 taatggtaaa ggtgttgcca ttgtcaaatc aactgaacaa gcagggaaat tcacccttac
    17161 tgcccactct gatctcttga aatcgaacca agtcactgtc tttactggta agaaagaagg
    17221 acaagaaaag actgttttgg ggacagaggt gccaaaagta cagaccatta ttggagaggc
    17281 acctgaaatg cctaccactg ttccgtttgt atacagtgat ggtagtcgtg cagaacgtcc
    17341 tgtaacctgg tctttagtag atgtgagcaa gcctggtatt gtaacggtga aaggtatggc
    17401 tgacggacga gaagtagaag ctcgtgtaga agtgattgct cttaaatcag agctaccagt
    17461 tgtgaaacgt attgctccaa atactaactt gaattctgta gacaaatttg tttcctatgt
    17521 tttgactgat ggaagtgtac aagagtatga agtggacaag tgggagattg ccgaagaaga
    17581 taaagctaag ttagcaattc caggttctcg tattcaagcg accggttatt tagaaggtca
    17641 accaattcat gcaacccttg tggtagaaga aggcaatcct gcagcacctg tagtgccaac
    17701 tgttactgtt ggaggtgaag cagtaacagg tcttactagt cgacaaccaa tgcaatatcg
    17761 tactctatct tatggtgccc aattgccaga agtcacagca agtgctgaaa atgctgatgt
    17821 gacagttctt caagcaagcg cagcaaacgg catgcgtgcg agcatcttta ttcagcctaa
    17881 agatggtggc cctcttcaaa cctatgcaat tcaattcctt gaagaagcgc caaaaattgc
    17941 tcacttgagc ttgcaagtgg aaaaagctga cagtctcaaa gaagaccaaa ctgtcaaatt
    18001 gtcggttcga gctcactatc aagatggaac gcaagctgta ttaccagctg ataaagtaac
    18061 cttctctaca agtggtgaag gggaagtcgc aattcgtaaa ggaatgcttg agttgcataa
    18121 gccaggagca gtcactctga atgctgaata tgagggagct aaaggccaag ttgaactcac
    18181 tatccaagcc aatactgaga agaagattgc gcaatctatc cgtcctgtaa atgtagtcac
    18241 agatttgcat caaaaaccta ctcttccaac aacagtaacg gttgagtatg acaaaggttt
    18301 ccctaaagct cacaaagtca cttggcaagc tattccgaaa gaaaaactag actcctatca
    18361 aacatttgaa gtactaggta aagttgaagg aattgacctt gaagcgcgtg caaaagtctc
    18421 tgtagaaggt atcgtttcag ttgaagaagt cagtgtgaca actccaatcg cagaagcacc
    18481 acaattacca gaaagtgttc ggacatatga ttcaaatggt cacgtttcat cagctaaggt
    18541 tgcatgggat gcgattcgtc cagagcaata cgctaaggaa ggtgtcttta cagttaatgg
    18601 tcgcttagaa ggtacgcaat taacaactaa acttcatgtt cgcgtatctg ctcaaactga
    18661 gcaaggtgca aacatttctg accaatggac cggttcagaa ttgccacttg cctttgcttc
    18721 agactcaaat ccaagcgacc cagtttcaaa tgttaatgac aagctcattt cctacaataa
    18781 ccaaccagcc aatcgttgga caaactggaa tcgtactaat ccagaagctt cagtcggtgt
    18841 cctattcgga gattcaggta ttttgagcaa acgttcagtt gataacttaa gcgttggctt
    18901 ccatgaagac catggagttg gtgcaccgaa gtcttatgtg attgagtatt atgttggtaa
    18961 gactgtccca acagctccta aaaaccctag ttttgttggt aatgaggacc atgtctttaa
    19021 tgattctgcc aactggaaac cagttactaa tctaaaagcc cctgctcaac tcaaggctgg
    19081 agaaatgaac cactttagct ttgataaagt tgaaacctat gctgttcgta ttcgcatggt
    19141 gagagcagac aacaaactag gaacgtctat cacagaggta caaatctttg cgaaacaagt
    19201 tgcggcagcc aagcaaggac aaacaagaat ccaagttgac ggtaaagact tagcaaactt
    19261 caaccctgat ttgacagact actaccttga gtctgtagat ggaaaagtta cggcagtcac
    19321 agcaagtgtt agcaacaatg gcctcgctac cgtcgttcca agcgttcgtg aaggtgagcc
    19381 ggttcgtgtc atcgcgaaag ctgaaaatgg cgacatctta ggagaatacc gtctgcactt
    19441 cactaaggat aagaacttac tttctcataa accagttgct gcggttaaac aagctcgctt
    19501 gctacaagta ggtcaagcac ttgaattgcc gactaaggtt ccagtttact tcacaggtaa
    19561 agacggctac gaaacaaaaa acctgacagt tgaatgggaa gaagttccag cggaaaatct
    19621 gataaaagca ggtcaattta ccgttcgagg ccatgtcctt ggtagtgatc ttgttgctga
    19681 ggtcactgta cgagtgacag acaaactagg cgaagctctt tcagataacc ctaactatga
    19741 tgaaaacagt aaccaggcct ttgcttcagc aaccaatgat attgacaaaa actctcatga
    19801 ccgcgttgac tatctcaatg acggagatca ttcagaaaat cgtcgttgga caaactggtc
    19861 tccaacacca tcttctaatc cagaagtatc agcgggtgtg atcttccgtg aaaatggtaa
    19921 gattgtcgaa cggactgttg cgcaagccaa acttcgtttc tttgcagata gtggtacgga
    19981 tgcaccaact aaactcgttt tagaacgcta tgtcggtcca gagtttgaag tgccaaccta
    20041 ctattcaaac taccaagcct acgacgcaga ccatccattc aacaatccag aaaattggga
    20101 agctgtgcct tatcgtgcgg ataaagacat cgcagctggt gatgaaatca acgtaacatt
    20161 taaagctgtc aaagccaaag ctatgagatg gcgtatggag cgtaaagcag ataagagcgg
    20221 tgttgcgatg attgagatga ccttccttgc accaagtgaa ttgcctcaag aaagcacgca
    20281 atcgaagatt cttgtagatg gaaaagaact tgctgatttc gctgaaaatc gtcaagacta
    20341 tcaaattacc tataaaggtc aacggccaaa agtctcagtt gaagaaaaca atcaagtagc
    20401 ttcaactgtg gtagatagtg gagaagatag ccttccagta cttgttcgcc tcgtttcaga
    20461 aagtggaaaa caagtcaagg aataccgtat ccagttgact aaggaaaaac cagtttctga
    20521 gaagacagtt gctgctgtac aagaaaatct tccaaaactc gaatttgttg aaaaagattt
    20581 ggcctacaag acagttgaga aaaaagattc aacactgtat ctaggtgaaa ctcgtgtaga
    20641 acaagaagga aaagttggaa aagaacgtat ctttacagcg attaatcctg atggaagtaa
    20701 ggaagaaaaa ctccgtgaag tggtagaagt tccgacagac cgcatcgtct tggttggaac
    20761 caaaccagta gctcaagaag ctaaaaaaac acaagtgtcc gaaaaagcag atacaaaacc
    20821 aattgattca agtgaagcta gtcaaactaa taaagcccag ttaccaaata caggtagtgc
    20881 ggcaagccaa gcagcagtag cagcaggttt agctcttcta ggtttgagtg caggattagt
    20941 agttactaaa ggtaaaaaag aagactagaa attttgatac cttctttatc attaaagacc
    21001 aaagaaaaac tcttgtccta aatagaagat aaagagtctg ggacaaaata gttctcaacc
    21061 acaaaaaagc tagatatttc caattgcgga actctagctt tttaattttg agtcgttctc
    21121 ttattgtata gtagattgaa actagagtag tacacttcta cttctaaaac attgttagaa
    21181 atcgatttga ctgtccttat cgatttgtcc tgttcttatt tcatttcact atgttttagg
    21241 aggttattgg ccataagtac caatcccatg tcaattctca cttgacgctt gcctctcaga
    21301 ttacatctct tgtaacccaa acaagccttt atctgcccaa agacaggttc cacatcaatc
    21361 ttgcgttgag cgaaaatctg tctaccttgg ggagataaaa gcgcctgaca ttctttagct
    21421 ttcaagtttt gatagcgttc gttcatatac agtccctttt gagggactga ttcaggttca
    21481 tcagcgtagt aaaccttgat ttcctgttga aagtctgtct gtgttttctg gtacttgata
    21541 tggtgaaaac gatagcacca gccatcagga tgtgtgtagc tatcctcctt gtcattatag
    21601 tgccaattcg ctaagttttt agctgactgt ttataccctc tcttttgttt cttatcaaac
    21661 atggcatatt taatcagaag gggagtgatt tcttcttgaa aatagacttg tatctgttct
    21721 tgaagtttgg cggagaattt ctctgtcgtt ttcttccaca caaaactata cttgttggca
    21781 ttggcttcaa tcttagttcc gtcaataaac aaacaatcta aggtcactaa ctcttccatt
    21841 tttcaatttt tcgaccagag aaaatccctt gtgaataggc aaatagaaga gtagatacaa
    21901 gcattttagg gtgataagac gggcgaccaa aggcatgata gaaggcgtgg aaatgacaat
    21961 cctccaaggt attcaccact ttttcaatag taaaaacgag atggtcttgt ggtaagaagg
    22021 aactgatttc tagtggtaaa gttgtttgat ttgtgttata gtgaatatgc atgggatagt
    22081 ctttctaaat ggtttattaa gcaattctat tttaccaaga ctatcgtaac catgcaaaaa
    22141 agcaacggca aatccgttgc ctttttggat ataagagact attgtcccag actcttttct
    22201 ttgtataaaa ttgtatagtg ttattgtcta tactattttg tagagaaagc aaaaatccct
    22261 agaaaatgct tagggattcg actatttcat taagaacaat tcaacaatca tttctatata
    22321 catgataagg gttaataaga atcctgcacg ccagaagaat ttgatgaatt taggatagta
    22381 aaagctgcgt ttttttaaaa ggaagaaaaa gacgagaata atggctagga acgagagggc
    22441 tagccccagt ctagggagga aattatgggt aaaggtttta gctgtaatca agtaatactc
    22501 aaataccaag actggaaaag ccaaatccgc aaagtttcgt cctagttttt ttaatctaaa
    22561 aagtttggtt aggataatgc agacgactaa ggtcagtatc aataataaaa tagatgctaa
    22621 tttcattaaa atcataccca tattgtatca taaaaaaagg ctaatggaaa cgagaaacag
    22681 aggaatttat aggaaagtca ggcttttgag attgtgggtg atttttgtta taatgaaagt
    22741 tataaaatct tataatacct tgaatgatta ttatcgaaaa ctctttggag aaaagacttt
    22801 taaagtccct attgatgcgg gatttgactg tcccaatcgt gatggaactg tggctcatgg
    22861 aggctgtact ttttgtacgg tttccggttc tggagatgcc attgtggcac cagatgcgcc
    22921 tatccgtgag caattttata aggaaattga ctttattcat cgtaagtggc cagatgttta
    22981 gaagtatctg gtttattttc aaaattttac caacacccat gaaaaggtgg aagttattcg
    23041 agagcgttat gaacaggcta tcaatgagcc aggtgtggta ggaatcaata ttggaacgcg
    23101 cccagactgt ttaccagacg aaaccatcga atatttggct gagttatcgg agtgcatgca
    23161 tgtgacggtt gaattgggct tgcaaactac ttatgaagca acctctgacc tgattaaccg
    23221 tgcgcattct tatgaattgt aggtggaaac ggtcaagcgt ttgagaaagt atccaaaaat
    23281 tgagattgtt tcccatttga tcaatggttt gcctggtgaa acccatgaga tgatggttga
    23341 aaatgtccgc cgttgtgtca cggataacga tattcaaggg attaaactgc atttgctcca
    23401 tcttatgaca aatactcgta tgcaacgaga ttaccatgag gggcgtttac aattgatgag
    23461 tcaggacgaa tatgtcaggg tcatctgtga ccaactggaa attattccca aacatatcgt
    23521 catccatcga attacaggag atgcgcctag ggatatgctg cttgggccta tgtggagcct
    23581 caataaatgg gaagctctca acagcattga gatggagatg cgacgtcgtg gaagtgttca
    23641 aggatgcaag gctgtaaaac aggagtttga aaatgaaaag accacttgag atggcacatg
    23701 attttttggc tgaggtcgtg acaaaagagg atgtcgtagt ggatgcgact atgggaaatg
    23761 gtcatgacac gcttttttta gccaagctag ccaagcaagt ctatgccttt gatattcaga
    23821 agcaagcctt ggaaaagacc caagagcgtt tgcatcaggc tgacttgaca aatgcccagt
    23881 taatcttgca aggccatgag acactggacc agtttgtgat aaaagctaag gcagggattt
    23941 ttaatctggg ctatttgccg tcagctgata agtctgtcat cacccgaccg cagacaacga
    24001 ttgaggcatt agaaaagcta tgtggcttac ttgtcaaagg tggacgaatt gctattatga
    24061 tttactatgg tcatgaagga ggcgatctcg agagagatgc tgtcttggat tttgtgatcc
    24121 agttgaacca acaagagtac acagctgcca tttaccgaac tttaaaccaa gtcaacaacc
    24181 cgccgttttt agtgatgatt gaaaaattag agagatacag acatggataa acaataccta
    24241 cacgaaaagc tggatgccat gcgccagaat tttgttgaat caacccacca cgaacgagcg
    24301 gtgggcgtgc tagaccaagc gcatatgagc aaaaaaatgc ttaaaatcaa gaaaaaatta
    24361 gttgctcttg aaatggaacg gtgccagaga aaaattgagc acaaagattg ttccaagatt
    24421 gaccaaaaaa tcaaagagca gaaggagata tttgaatcct gttgtaaaaa agattaagga
    24481 ggacgtgcgt ggaattactg atttacctca tcctattttt actggttttg attgtctcaa
    24541 gtacaaccaa taagctcctg ccctttttgc ctctcccttt ggtgcaaatt cttttgggaa
    24601 ttgtgattgg tctcttttta cccaataccg actttcacct caatacggag ttgtttttgg
    24661 ccctggttat cggacccttg cttttccgag aggctgaaga agcagatgtt acggctattt
    24721 taaaacactg gcgaatcatt gtttatctca tatttccagt gatttttatc tcgaccctga
    24781 gtttgggtgg cttggcccat cttctttggt tcagccttcc cttggcagct tgcttggctg
    24841 ttggggcagc ccttggtcct acggacttgg tggcctttgc ctctctttcg gagcgtttta
    24901 gctttcctaa gcgcgtgtcc aatattctta agggcgaagg actcttgaat gatgcttctg
    24961 gtttggtggc ttttcaggta gctttgacag cttggacaac tggagctttt tctctggggc
    25021 aagctagcag ttcgctcatc ttttcaatcc taggcggttt tttaattgga tttttaacag
    25081 ccatgaccaa ccgcttcctc cataccttct tgctaagtgt gcgcgcaacg gatattgcca
    25141 gtgaactttt attagaattg agtttgcctc tagtgacctt ctttctggca gaagaagtcc
    25201 atgtttcagg gattattgcc gtcgtagttg ctggaatttt aaaggcaagt cgcttcaaga
    25261 aaatcacgct cctcgaagcc caagtggata cggtgaccga gacggtctgg catacagtga
    25321 cctttatgct caacggttct gtctttgtga ttttagggat ggagttggaa atgatagcag
    25381 aacctatctt gaccaatcca atctataatc ctctactttt attgctatct ctcatcgtcc
    25441 ttacctttgt cttctttgtc attcgtttta ttatgatcta tggctattat gcctatagaa
    25501 cccgacgcct caagaaaaag ctaaataagt atatgaagga catgtttctc ttgacctttt
    25561 caggtgttaa gggaacggtg tcgattgcta cgattctctt gataccaagt aatctagaac
    25621 aggagtatcc tctcttgctt ttccttgttg caggtgtgac gcttgtcagc tttttaacag
    25681 gtctcttggt cttgcctcat ctttctgatg aagaggaaga aagcaaggat tatctcatgc
    25741 atatcgccat tttgaatgaa gtaacgctag agttggaaaa agagttggaa gacaccagaa
    25801 ataaacttcc cctctatgcg gctattgaca attatcatgg acgtattgaa aatctcattt
    25861 taagccaaga aaaccaggat gatcaagaag attgggctgc tttgaaactc ttgattctta
    25921 gtattgaaag tgatggtttg gaacaggcct atgaagaggg gaacattagc aatcgtgctt
    25981 accgagttta ccaacgttat ctgaaaaata tagaacaagg aatcaatcgt aaacttgcct
    26041 caagactgac ctattatttc cttgtttctt tgcggatttt acgttttctc cttcatgaag
    26101 tttttactct cggaaagacc ttccgtagct ggaagaacaa ggagcaaagc cgtctccgtg
    26161 ctcttgatta tgaccaaatt gcagagctct atcttgccaa tacggagatg attattgaaa
    26221 gtttggaaaa cctgaaggga gtctacagac gctctttgat tagttttatg caggagtctc
    26281 gtcttcgaga aacaactatt atcagcagtg gtgcctttgt cgaacgggtt atcaatcgtg
    26341 tcaaacccaa caatatcaat gaaatgctga gaggctatta tctggagcgc aagttgattt
    26401 tcgaatacga agaaaaacga ttaattacaa ctaagtatgc caagaaatta cgacaaaatg
    26461 taaataactt agagaactat tccttgaagg aagctgccaa taccctgccg tatgatatgg
    26521 tggaattggt aagaagaaat tagttaatac tcttcgaaaa tctcttcaaa ccacgtcagc
    26581 gtcgccttac cgtatgtatg tgactgactt cgtcagtctt atctacaacc tcaaaacagt
    26641 gttttgagca gcctgcggct agcttcctag tttgctcttt gattttcatt gagtataaga
    26701 ttataagtga aggagtgtga catgaaaaag tggtggaaag agctgataga caagccttta
    26761 ttaaaagctt ttttgcatta ttatcaagca tcagatagtg agttgaccag tgtcgcagta
    26821 gcctactatt ggttgatttc gattttcccc ctgcttttgg tggtggtcaa tatcctcccc
    26881 tattttcaga ttcctgtggg agaatttctg ggctttatga aagacgtcct gcccccaagc
    26941 ctctatgaag gtgtggaaaa aatagccaga gaagtcttga cgcaaccttc aacaggttta
    27001 ttgagttttt ctgttttatc ggcgttatgg agtttttcaa aatctatgaa tttcttgcaa
    27061 aaagctttta acaaggctta tggcgtcgaa aagagtcgtg gacttatttc ccatcagatg
    27121 ctaagtctcc tagtcagttt tggcttgcag ctcctctttg cgtttgcctt gtttttgatc
    27181 ttatttggtc agatgatttt ggctttactt gctcattatt ggacaaaaga tggcattatc
    27241 tatcaggctt tacaagggtt ggcaggtcct ctgatttacg ccctcctctt tgctatcttg
    27301 gtcatgcttt attattttct tcccaatcta tctaacagga aaattagcta taccctacca
    27361 ggcagtgcct ttgttctctt agtgatttta ggtttactaa ctctgttctc tagttatctc
    27421 aattactatg tccatcattt ggtggatgtc cgaattttag gttccgttct tcttgttgtt
    27481 atgatgtttt ggtttatctt gattgctaaa attgttatcc taggcgcggt tatcaatgcc
    27541 agtatgcaga gtttgaaaga tccggtcttt aaaaaagact aactatttat ccattataaa
    27601 agcgcatagt atcaagactt tatagaacct tgatactatg cgcttttgcg cttttgtgct
    27661 ttgacagttt tttgtatagt ttttgtccaa gatttctaaa tcatctgatt aaattcctat
    27721 tttcccctat cattgtccct gttttttcga aaatggaagg agtataataa atctatcaat
    27781 aaaatgatag gaggaacttt atgggtcata ttttcttttt tctaagtgtc tttttggcag
    27841 ggattctatc cttcttttct ccttgtatct tacctttgtt accggtctat acaggagtgt
    27901 tactagatga taaggatggt gctcaggctt ctagcggcaa attttcaatc tcagttacta
    27961 gtttattacg aactctggcc tttatagcag gaatttcctt tatatttatt ttgttgggct
    28021 atggagctgg ttttttaggc gatttgcttt atgcttcttg gttccaatat cttactgggg
    28081 caattattat ccttcttggt ttgcaccaaa tggagattct acactttaag gggctttata
    28141 aggaaaagag gctacaactg caaggacagg ggcaaaatgg taagggctat agtcaggcat
    28201 ttttattggg cttgaccttt agttttgctt ggacgccttg cgtggggccg gttctggggt
    28261 ctgttttggc cttggcggct tcaggtggtt caggagcttg gcagggagct ggtctcatgt
    28321 tggtgtatac gctgggcttg gcgctaccat tcttgcttct agctctgacc tctagttatg
    28381 ttttgaaaca tttccgaaaa cttcatccct atctcggaat cctcaaaaaa gtgggtggtt
    28441 ttctcattat tgtgatggga ctcttggttc tgtttggaaa tgcttcaatt ttaagtcaat
    28501 tatttgaata aaatggaaag gaatatcaat atgaaaaaat ggcaaacatg tgttcttgga
    28561 gcaggttcgc tcctttgttt gacggcttgt tcaggcaagt ccgtgactag tgaacatcaa
    28621 acgaaagatg aaatgaagac ggagcagaca gctagtaaaa caagcgcagc taaagggaaa
    28681 gaggtggctg attttgaatt gatgggagta gatggcaaga cctaccgttt atctgattac
    28741 aagggcaaga aagtctatct caaattctgg gcttcttggt gttccatctg tctggctagt
    28801 cttccagata cggatgagat tgctaaagaa gctggtgatg actatgtggt cttgacagta
    28861 gtgtcaccag gacataaggg agagcaatct gaagcggact ttaagaattg gtataaggga
    28921 ttggattata aaaatctccc agtcctagtt gacccatcag gtaaactttt ggaaacttat
    28981 ggtgtccgtt cttacccaac ccaagccttt atagacaaag aaggcaagct ggtcaaaaca
    29041 catccaggat tcatggaaaa agatgcaatt ttgcaaactt tgaaggaatt agcctaggag
    29101 gcgtcttatg aatgataagt taaaaatctt cttgttgcta ggagtatttt ttctagccat
    29161 aaccggtttc tatgttctat tgatacgaaa tgcagggcag acagatgcct cgcaaattga
    29221 aaaggcggca gttagccaag gaggaaaagc agtgaaaaaa acagaaatta gtaaagacgc
    29281 agacttgcac gaaatttatc tagctggagg ttgtttctgg ggagtggagg aatatttctc
    29341 acgcgttccc ggggtgacgg atgccgtttc aggctatgca aatggtagag gagaaacaac
    29401 caagtacgaa ttgattaacc aaacaggtca tgcagaaacc gtccatgtca cctatgatgc
    29461 caagcaaatt tctctcaagg aaatcctgct tcactatttc cgcattatca atccaaccag
    29521 caaaaataaa caaggaaatg atgtggggac ccagtaccgt actggtgttt attacacaga
    29581 tgacaaggat ttggaagtga ttaaccaagt ctttgatgag gtggctaaga aatacgatca
    29641 acctctagca gttgaaaagg aaaacttgaa gaattttgtg gtggctgagg attaccatca
    29701 agactatctc aagaaaaatc caaatggcta ctgccatatc aatgttaatc aggcggccta
    29761 tcctgtcatt gatgccagca aatatccaaa accaagtgat gaggaattga aaaagaccct
    29821 gtcacctgag gagtatgcag ttacccagga aaatcaaaca gaacgagctt tctcaaaccg
    29881 ttactgggat aaatttgaat ccggtatcta tgtggatata gcaactggag aacctctctt
    29941 ttcatcaaag gacaagtttg agtctggttg tggctggcct agttttaccc aacccatcag
    30001 tccagatgtt gtcacctaca aagaagataa gtcctacaat atgacgcgta tggaagtgcg
    30061 gagccgagta ggagattctc accttggcca tgtctttacg gatggtccac aggacaaggg
    30121 cggcttacgt tactgtatca atagcctctc tatccgcttt attcccaaag accaaatgga
    30181 agaaaaaggc tacgcttatt tactagatta tgttgattaa tacttttcga aaatctcttc
    30241 aaaccacgtc agcgtcgcct taccgtatgt agggtt
//
LOCUS       DAVMAH010000028        29734 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVMAH010000028 DAVMAH010000000
VERSION     DAVMAH010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29734
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.028"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            1..959
                     /locus_tag="VYO94_001152"
                     /pseudo
     CDS             1..959
                     /locus_tag="VYO94_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1059..2681)
                     /gene="groL"
                     /locus_tag="VYO94_001153"
     CDS             complement(1059..2681)
                     /gene="groL"
                     /locus_tag="VYO94_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV1759794.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(2697..2981)
                     /gene="groES"
                     /locus_tag="VYO94_001154"
     CDS             complement(2697..2981)
                     /gene="groES"
                     /locus_tag="VYO94_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV1759795.1"
                     /translation="MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(3137..3532)
                     /locus_tag="VYO94_001155"
     CDS             complement(3137..3532)
                     /locus_tag="VYO94_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1759796.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3610..4371)
                     /locus_tag="VYO94_001156"
     CDS             complement(3610..4371)
                     /locus_tag="VYO94_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1759797.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKA
                     EFAETFPNQTVWTFLLDVTDMTMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(4413..5039)
                     /locus_tag="VYO94_001157"
     CDS             complement(4413..5039)
                     /locus_tag="VYO94_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV1759798.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(5055..5372)
                     /locus_tag="VYO94_001158"
     CDS             complement(5055..5372)
                     /locus_tag="VYO94_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV1759799.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(5369..5668)
                     /locus_tag="VYO94_001159"
     CDS             complement(5369..5668)
                     /locus_tag="VYO94_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV1759800.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(5953..6144)
                     /locus_tag="VYO94_001160"
     CDS             complement(5953..6144)
                     /locus_tag="VYO94_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV1759801.1"
                     /translation="MSYSVDDVVSNAFKKRMILDSFFAFNCSGTMKASTWVYDKGEWY
                     YVSSSGAMIANDWVKDNGK"
     gene            complement(6304..6978)
                     /locus_tag="VYO94_001161"
     CDS             complement(6304..6978)
                     /locus_tag="VYO94_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759802.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            complement(6984..7430)
                     /locus_tag="VYO94_001162"
     CDS             complement(6984..7430)
                     /locus_tag="VYO94_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1759803.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEVADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7544..8047)
                     /locus_tag="VYO94_001163"
     CDS             complement(7544..8047)
                     /locus_tag="VYO94_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1759804.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVFIPATGFVILSLLRKKINAPRPYEEWDIKPLLDRDSPGQSM
                     PSRHVFSATIISMTCLHASLTVGFILLVLSALLGLVRVLGGVHYPKDVVVGYICGLAW
                     GVLFLLF"
     gene            complement(8044..8406)
                     /locus_tag="VYO94_001164"
     CDS             complement(8044..8406)
                     /locus_tag="VYO94_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV1759805.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(8472..9894)
                     /locus_tag="VYO94_001165"
                     /pseudo
     CDS             complement(8472..9894)
                     /locus_tag="VYO94_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(9964..10413)
                     /locus_tag="VYO94_001166"
     CDS             complement(9964..10413)
                     /locus_tag="VYO94_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1759806.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVRFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNSLVELEASPVDKRAKFVRLMDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(10537..11253)
                     /locus_tag="VYO94_001167"
     CDS             complement(10537..11253)
                     /locus_tag="VYO94_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1759807.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(12136..13551)
                     /gene="ply"
                     /locus_tag="VYO94_001168"
     CDS             complement(12136..13551)
                     /gene="ply"
                     /locus_tag="VYO94_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV1759808.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVDAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13562..13894)
                     /locus_tag="VYO94_001169"
     CDS             complement(13562..13894)
                     /locus_tag="VYO94_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759809.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13965..14573)
                     /locus_tag="VYO94_001170"
     CDS             complement(13965..14573)
                     /locus_tag="VYO94_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759810.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14586..15044)
                     /locus_tag="VYO94_001171"
     CDS             complement(14586..15044)
                     /locus_tag="VYO94_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV1759811.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            15169..15568
                     /locus_tag="VYO94_001172"
                     /pseudo
     CDS             15169..15568
                     /locus_tag="VYO94_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(16306..16566)
                     /locus_tag="VYO94_001173"
     CDS             complement(16306..16566)
                     /locus_tag="VYO94_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759812.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFLDG"
     gene            complement(16625..17176)
                     /locus_tag="VYO94_001174"
     CDS             complement(16625..17176)
                     /locus_tag="VYO94_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759813.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFQFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(17166..18161)
                     /locus_tag="VYO94_001175"
     CDS             complement(17166..18161)
                     /locus_tag="VYO94_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759814.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     CRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(18569..18883)
                     /locus_tag="VYO94_001176"
     CDS             complement(18569..18883)
                     /locus_tag="VYO94_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759815.1"
                     /translation="MYDEINIPTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDL
                     TRNHDSNKIIGKGEATSIFLAKKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAF
                     KA"
     gene            complement(18987..19481)
                     /locus_tag="VYO94_001177"
     CDS             complement(18987..19481)
                     /locus_tag="VYO94_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759816.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLGHYIKSTEQLLENNRISQGKYEELLLDAFRYDIVYGLDEEGE
                     LSFD"
     gene            complement(19527..19733)
                     /locus_tag="VYO94_001178"
     CDS             complement(19527..19733)
                     /locus_tag="VYO94_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759817.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(19720..19881)
                     /locus_tag="VYO94_001179"
     CDS             complement(19720..19881)
                     /locus_tag="VYO94_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1759818.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(20227..21183)
                     /gene="lytA"
                     /locus_tag="VYO94_001180"
     CDS             complement(20227..21183)
                     /gene="lytA"
                     /locus_tag="VYO94_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1759819.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(21559..22929)
                     /locus_tag="VYO94_001181"
     CDS             complement(21559..22929)
                     /locus_tag="VYO94_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1759820.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFAFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWNKSLYVDLLEQGLAMGLMSSIVSIGSVILQSSVNTLGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(23235..24401)
                     /gene="recA"
                     /locus_tag="VYO94_001182"
     CDS             complement(23235..24401)
                     /gene="recA"
                     /locus_tag="VYO94_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV1759821.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(24456..25712)
                     /locus_tag="VYO94_001183"
     CDS             complement(24456..25712)
                     /locus_tag="VYO94_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV1759822.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(25797..26813)
                     /locus_tag="VYO94_001184"
     CDS             complement(25797..26813)
                     /locus_tag="VYO94_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1759823.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(26821..27339)
                     /locus_tag="VYO94_001185"
     CDS             complement(26821..27339)
                     /locus_tag="VYO94_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1759824.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            complement(27329..27772)
                     /gene="tsaE"
                     /locus_tag="VYO94_001186"
     CDS             complement(27329..27772)
                     /gene="tsaE"
                     /locus_tag="VYO94_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV1759825.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(27858..28478)
                     /locus_tag="VYO94_001187"
     CDS             complement(27858..28478)
                     /locus_tag="VYO94_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759826.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(28861..29724)
                     /locus_tag="VYO94_001188"
     CDS             complement(28861..29724)
                     /locus_tag="VYO94_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1759827.1"
                     /translation="MSTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEAKELCKIYNNPLMLMK
                     IENYLKELDTV"
BASE COUNT         8898 a         6623 c         5068 g         9145 t
ORIGIN      
        1 aagatttcta tgaccgatat tgcccatcag ctttccatct caacttcaac tgttattcgt
       61 aagctcaatg attttcactt taaacatgat ttttcttgtc ttcctgagat tatgtcttgg
      121 gatgagtatg cttttacaaa gggaaagatg agtttcattg cgcaagattt tgataatctt
      181 aatattatca ctgttcttga aggcagaaca caagctgtca tccgaaatca ctttcttcgc
      241 tacgatagag ccgttcgttg tcaagtgaaa atcattacga tggatatgtt tagtccttac
      301 tatgacttgg ctaaacagct tcgatttcaa atttctaggc tcaggctgaa acagtctccc
      361 agactgtttc actcccgaat gctaaaatcg ttcttgatcg ctttcacatt gtacaacatc
      421 ttagccgtgc catgagtcgt gtgcgtgtcc aaatcatgaa tcagtttcat cgaaaatccc
      481 atgaatacaa ggctatcaag cgctactgga agctcataca acaggatagt cgtaaactga
      541 gtgataagcg attttatcgt cctacttttc gtatgcattt aaccaataaa gagattttag
      601 acaagctttt gagctattca caagacttga aacatcacta tcagctctat caactcttgc
      661 tgtttcactt tcagaataag gaaccagaga aatttttcgg acttattgag gacaatctta
      721 agcaggttca tcctattttt cagactgtct ttaaaacctt cctcaaagat aaagaaaaga
      781 ttgtcaacgc ccttcaacta cactattcta atgccaaact ggaagcgacc aataatctca
      841 tcaaacttat caagcgcaat gcctttggtt ttcgaaactt tgaaaacttc aaaaaacgga
      901 ttttcatcgc tctgaatatc aaaaaagaaa ggacaaaatt tgtcctttct cgagcttagc
      961 ttttcttcaa cccactacag ttgacaaaga gcctataaaa agaagggtta gtcattccct
     1021 ccttttgtgt tttttataag ttgttttcta tagaaagctt acatcatccc gcccatcata
     1081 cttggatcca ttgctggagc tggggctact ggttctggtt tattggctac gactgcttct
     1141 gttgtcaaaa tcaagctggc tacagatgct gcattttgta gggctgaacg actcacttta
     1201 actggatcaa tgataccttg atcaatcatg ttaacccact cgccagttgc tgcgttgaat
     1261 cctataccaa gctcagcatt tttcaaacga tcgataacga tagatccttc aaatcctgca
     1321 ttgtgagcaa tttgacgaac gggttcttcc aaagcacgga gaacaatatt acgtcctgtt
     1381 gcttcatctc ctgtcaattc caaggtagca acagctggaa tcacattggc aagagctgtt
     1441 ccaccacctg caacaatacc ttcttcaaca gctgcacgag tagcgttgag ggcatcttca
     1501 atgcggagtt tcatttcttt caactcagtt tcagttgcgg ctccgacctt aataaccgct
     1561 acaccacctg acaatttggc caagcgttct tgcaattttt cacggtcaaa ttcagaagtt
     1621 gtagtttcga tttgagactt gataaccgca acacggtgag aaatcgcttc aggatttcct
     1681 gcaccttcta caataaccgt gctatctttg tccacggtca ctctcgctgc ttgaccaaga
     1741 gcttcaattg tcgcatcttt caactcaaga ccaaggtctt ctgtgataac tgttccgcct
     1801 gttaagatgg cgatatcttc aagcatggct ttgcgacggt caccaaaacc aggtgccttg
     1861 actgctacta cgttgaaggt tccacgaatc ttgttcaaaa caagagttgg aagagcctca
     1921 ccatccacat catccgcaat aatcaagagt ggacgattgc tttggagaat gctttccaaa
     1981 agtggcaaga tttcttggat attggaaatt ttcttgtctg taatcaaaat gtacggattt
     2041 tcaaggtcag ccaccatttt ttcgctatct gtcaccatgt actgtgaaag gtaaccacgg
     2101 tcaaactgca ttccttctac gacttcaagc tctgtttcca taccacgtga ctcttcgatg
     2161 gtgatgacac cgtctttgcc aactttttcc attgcttcag agatgtactc accaactttt
     2221 tcagaacgag aagatacggc tgcaacttga gcgatagctt ctttattggc aacagggatg
     2281 gcgttgtttt tcaaagcttc aactgctgcg gcaactgctg tttcaatccc acgacgaata
     2341 ccgattggat ttgcacctgc tgtgacgttt ttgattcctt cacggacgat agcttgggtc
     2401 aagactgttg cagtcgtagt cccgtcacct gcgatatcat tggttttaga agctacttct
     2461 gatactaact tagcacccat attttcaaaa tggtcttcca attcgatttc tttggcaatg
     2521 gtcacaccgt cattggtaat caagggtgaa ccgaatgact tttcaagaac gacattgcga
     2581 ccttttggtc ccaaggttac tttaacagtg tctgcaagga tatcgacacc acgaaccatg
     2641 gctgaacggg catctgatga aaatttaatt tcttttgaca tacttacttt ctccttctat
     2701 tcctcaatga ttgccaaaat gttagcttcg cctacgatga tatacttttc atcgccatct
     2761 ttgacatcaa gacctgcgtg ggcttcaact aagacacggt ctccagtttt aacacttgga
     2821 gcaaccaagt caccgttcaa ggtacgaaca ccttgtccag tagccacaac ttgggctgtt
     2881 ttggtttttt cttgggctga acctgcgaga acaaagcctc caacagtttg ttctttttct
     2941 tctactttta agaccacacg gtcccctaat ggtttcaaca tctgatttcc tccataatga
     3001 gatagatatt attagcactc tttatacctg agtgctaatt catagttcta ttgtatcact
     3061 tagtcagaaa taatcaagaa aaaagtctga ctttctcaag ataaaaagcc tgagaccaac
     3121 tcagactttt taattcttaa aatggcaatt cttcctcttc caagaccaaa tctgccaaat
     3181 cttggcctgc attattttca cgcatagcac gttgggcacg actttccaag agttggaatc
     3241 ctgtcacaag gacttcggtt acataattca tctgaccatt tttctcaaag cgacgggtac
     3301 gcaattctcc atcaacggaa atgagactac ctttggttgc gtagcttgcc aaagtttctg
     3361 ctagcctgcc ccataggacc atattgacaa aatcaacttc acgttcaccg ttttggtctt
     3421 tgtaacgacg gttgacagcg atagttgctc gcgctactga cttgtcattg ttggttttgt
     3481 gcaattctgg tgtagacgtt aaacgtccaa tcaagataac tttattatac atattttctt
     3541 cctcctactt atctattcgt aggaaatcaa aaaaagttac agaaatttgt aacttttcga
     3601 gaaaattttt tattttttat gaaccatgaa acctgtcgcc tgttgattgg ccataatggt
     3661 catatctgta atctgaacac gacgaggttg actagtcaca tagactactg tatctgcaat
     3721 atcctgagct tgcaaagctt ctattccttg gtaaacggac gcagctcgtt ctttatcacc
     3781 atgaaaacgc actgtagaaa aatctgtttc gacaattcca ggctgaatgg tcgtcacctt
     3841 gatatccgtt gcgatggtat caattcgcag tccatctgaa aaggtcttaa ctgccgcctt
     3901 ggtggctgag taaacagctg caccagcata ggcataaatt cctgcggttg accccatatt
     3961 gataatatga ccttgattgg cttttaccat tgctggcaag aaacagcgag taaccgccat
     4021 cagaccttta acattggtat ccaacatggt caacatatcc aactcctcat agtcttgata
     4081 gggagccaag tcaagagcca gtccggcgtt gttgaccaag atatcaatcc tccctatcgt
     4141 ttctagaata tcagagcaga cagtctttac cattgtcata tccgtgacat ctaggagaaa
     4201 agtccaaact gtttgatttg gaaaagtttc tgcaaactcc gccttaagag cttctagtct
     4261 gtctatccgt cgtcctgtta gaacgacatc ctcaccctgc tccagataag cacgcgcaat
     4321 cgcttcaccg attcctgatg tcgctcctgt aatcacaaca ttttttgcca tcttatttcc
     4381 ttctagctgg tctatcagat attaacaact tcttaggcag tccagtgttt cgctgggtcg
     4441 aacggtgttc cgacaacttg gtcttctgat aattcaagca ccccacgttt ttgcggagca
     4501 tttggcaaat gcaattcacg aggactacac atcatcccaa aactcttttc accacgaagt
     4561 tcgcctggga aaatgaaatt cccttttggc atcatggcac caggaagagc cacaatggtt
     4621 ttcaacccaa cacgcgcatt aggtgctcct gcaacgattt gcactatctt gtcacttgcg
     4681 actgcaactt ggcagatgtt gaggtggtca ctgtctggat gagctaccat ctcgacaatt
     4741 tcaccaacaa caaacttagg ttccttatca ttaacaattt cttctgtaaa accttccgcc
     4801 tgtaattctt ggttcaaacg agcgacttgc tcatctgata aaaagacttg accgcgctct
     4861 gcaatttcaa acaagctcga aacctcaaaa atgttccaag ctactgtttc cccattttct
     4921 ttgaggaaaa cacgggctac cttgcctttg cgttccacat tcagtttggc atctccgcta
     4981 tttttcacga tgaccataag gacatcaccg acatgttctt tgttatacgt aaaaatcatt
     5041 gtttcctttt tctcctattt caatcctgct aaaaaatcgt taatttgctc cttactttta
     5101 cggtcgcgat tgacaaaacg accaatttcc ttgtcctttt ctagaacaac aaggctagga
     5161 attccgtaaa catcccagag tttggccaaa tccatatact gatctcggtc cattcgaata
     5221 aaggtgaact ctggattggt ctcctcaatc tctggtaagg caggataaat ataacgacaa
     5281 tcgccacacc agtctgccac aaaaaggaag accttcttgc ccgctttttc cactaaagat
     5341 gctaattctt ctaaacttgc tggctgtatc ataagacttc ctcctcatag actaggtctt
     5401 cattttcata gacaaaggta taatgacggc catcctcaaa aataacgcca ccaaccaagc
     5461 tctccagact gctttcgtaa acttgaacat agagggtcgc aatttccccc atgtcggaaa
     5521 aatggtctcg cacaatctct gtcaactctt cctgagtctt catgagctta cggtcatctg
     5581 caactttttt cgtggcaaga gcaaggcttc cgatacctag cagagccaag cctgccatcc
     5641 acattttttt agctttcata ccattcattt taacacaaaa aaggcttcag gacaaatgag
     5701 gaagcagcag aaaagcaagt aaaaagcctc ttcctttaag gaaaaggact tcttatacta
     5761 agagcaaact agaaagctag ccgcaggctg ctcaaaacac gattttgagg ttgtagataa
     5821 ggcgacgttg acgtggtttg aagagatttt caaagagtat tattcttatt gccaggcacc
     5881 taagttgcca acgtagtaac catcaggtgt gtaggtattg cgaagcatct tacctgatga
     5941 agccagataa tactacttgc cattgtcttt gacccaatca ttcgcaatca tggctccaga
     6001 agaacttaca taataccatt ctcccttgtc ataaacccaa gtgcttgctt tcatggttcc
     6061 tgagcaatta aaggcaaaaa aactgtccaa tatcattcgt tttttaaaag catttgacac
     6121 tacatcatcc acgctgtagg acatagatac atcaaacgta agagccaaaa tatcgaaaaa
     6181 tatacaactt ttaaaggcaa catttcattt tttaaagtct aacaaccata gaactgaaat
     6241 cagagcaagg catcaacttc ctactcttag tacgtctatt ttgatggttg aagtgaagat
     6301 tttttattta acgtagacaa gctccaactt cccaaaagcc acatctccac ggataatcaa
     6361 ggttttactg gttggggcta caggagcgtc agccttagct gcaccaaagg aggtttctac
     6421 tttcaaatct acacgccagt gttgtggaac atagacggtt gcatttccga aggccacttc
     6481 aatatttaaa gttgcaaaat cacctagcat ctctgcatta tcatagtaga ttttagcatc
     6541 cccaaaagcg acttccactt ggtcatctac gagatcttga tcttgcttat agaaggtccc
     6601 gctaccaaaa gcgacttcct tatccgtgac gactgttttt ttcccattgt accaccattt
     6661 tttttcattc cagaacttac ttgaatgcgt cagataacca acaccaagta ccaccaagat
     6721 gctagcccaa ataagagaat gattggtaac tggtaacaag tcataagcgt aatttgcaat
     6781 gatgagcgcc agtaaacctg taaaaactgc cgaagtgaga tgacgtctaa ggatggactc
     6841 aatggactta taagcaaaaa aaacaatacc tagtaaaggc catattttac catccaaaga
     6901 aggaattcca aaattccctt gcaacaagat ccaagctgct aaaaccaata aaacaatacc
     6961 aaatgctttc tttttcatgt tttttacctc atgtttctta gattttcttt taggagggat
     7021 tggtaatgcc gtgagacatg aacctccttg tgcgtctgat aaaaggaaat ggtgcccgtt
     7081 cctgaaaagg acttgtccac tgagtaaatt tgacggatgt ttgcgatcgt tgacttggaa
     7141 actcgattaa aatagcgagg caagatagac tccaactcat agagcttgag gcgaacctca
     7201 taagcttcct tctggttatg agcgtagatc ttgctccctt ctgtttcaaa gaagagaatc
     7261 tctgacaggt ctagataata ttcacctgtc cccttgtaaa aagtcaacct cggagccttt
     7321 gactcttgca agagccgttg caagtctgca acttcatctg tcaaagtggg ggtcttgatg
     7381 acaatttcag tctcctctaa attgccgtca atctcaattc gtaacttcat cacatctcct
     7441 ttctgactct actatatcaa agccaaaata agaaaacaag agcaaaaaag caagtggtta
     7501 ctttagaccc gtaagtggtt gcaagaccaa cttaacttac aggtcaaaat agaaggaaaa
     7561 gcacacccca cgcaagacca caaatataac caactactac atccttggga taatgtacac
     7621 cacctaagac tctcacgaga ccgaggaggg ctgacaagac caacaagata aagcccacag
     7681 ttagactagc atgtaagcaa gtcatggaga taatggttgc tgaaaagaca tgacgactgg
     7741 gcatagactg accaggacta tctctgtcaa gcaagggttt aatatcccat tcctcataag
     7801 gcctaggggc attgattttc ttacgaagaa gggataaaat cacaaaacct gtagcaggga
     7861 taaacacata aaccccaact tgctgaccaa gtcctagttg caggtaagtg gtgactagca
     7921 agatcagata gaccaggggc atggcgactg tcatcaaacg attgaaactg cgtaatagga
     7981 ataaaagaat tggacgacta gttagtctgg agctgatatt tcgataccat tcttgataat
     8041 ttttcattta tgcttctcat acttttctag aacttgttga gatgttttcc ccttggcaag
     8101 ccaatccact agcttgtcca agcgacgtat ttcctgcatc agaggatcat caatttcctc
     8161 aatacggaca ccgcaaatct tccctgtaat tgcaattcgt tcagggacat aatatggtgc
     8221 ttgtctaaaa aaatctccgt aagtaacatc cctatccaga caagcaagaa catcactcac
     8281 ttcataccct gtcaaccaac tggtcacttg gtgaactgac tctgcctttc caccctttcg
     8341 ctcaactttt gcaatcaagg ctaagtagac agcagcaaat ttcatattgt ataatttctg
     8401 actcatactt ctctctttct atgtgtacta gtataaataa gaaaaagaag gccgtcaagc
     8461 cttcttttga tttattcttc tgcttcatct tctgtaaatt gactattgta caagtcagcg
     8521 tagaagccac cttgcgccat cagttcctca tagttgcctt gctcgatgat atttccatct
     8581 ttcatgacca agatcaagtc tgcatttcgg atggttgaca agcggtgggc aatgacaaag
     8641 gatgtgcgtc cttccatcaa acggtccatg gctttttgga tcaattcctc tgtccgtgtg
     8701 tcaacagaag aagtcgcctc atccaaaatc aaaagcgatg catccttaag aagggcacaa
     8761 gcaatagtca atagttgttt ttgtcctaca gacaaggtca cggtgtcatc caagatggta
     8821 tcatagccat ctggcaaggt cataataaag tggtgaattc ccacagcctt actagcttcc
     8881 atcattcgtt catcactaat ccctatttga ttatagatga gattgtctcg aatagttcct
     8941 tcaaagagcc agatatcctg caagaccatt gaaaaggcat catgcacttc tgaacgcgtc
     9001 atagccttgg tatccacacc atcaatgtga atacttccct tatcaatctc atagaatttc
     9061 atcaaaagat tgacaatggt tgtcttacca gtcccagtcg gcccaacaat ggcaaccttt
     9121 tgaccagcat gagctgtcgc agagaagtca tagtcttgaa cattgacacc gtccaccaga
     9181 atttctcctg ctgacacgtc gtagaaacgt ggaatcagat tgaccagagt tgatttacca
     9241 gaacctgttg acccaataaa ggccactgtt tgaccagttt ctgctttaaa gctaacatgt
     9301 tcaataactg cctccgaatt tgccgcatag cggaaggtca catcctttta aactctcacg
     9361 agtgatactg ttccgtttat ctgtcagccc ctgaatcaag gactgttttg gaaaggctag
     9421 cgtcatcaaa acggtcgtca tcaggacgtt gacaatcact gccacaagta cggcccagag
     9481 ccagtattct gaatgaccta aaatcttccc aatagcccag atagccataa ttggaccacg
     9541 cgttaccact tgcaagccca tagtaatcaa catttgaact tgagtaatgt cattggtagt
     9601 acgcgtcaag aggctaggaa ttgaaaattt cttaatctct gtctgcgagc aatccaaaac
     9661 tcggttaaaa atatcacttc tcagcctact agtataagaa gccgccactc gggatgcaaa
     9721 aaatccaact gcaactacgg acaagaaggc aagaaagggc attcccatca tcatgcttgc
     9781 cggctgccac aactcatcta aattagttcc ttgactacct agcaaatccg taattttcga
     9841 gatataggtc ggcacttcca actctagata gaccgaaaag caagtaaaga gaatggctag
     9901 taaagagaat ggctagtaaa atcatccccc attcttttct actaattctt ttggctaatt
     9961 tttttattct ctcctcctat tcccttgata ttttgcctgt agttgaccga gaactttctc
    10021 aaaaatcagt aattcatctt catcaatgtc ttccatcaac tgcttgtcta tgcgttcaaa
    10081 aaaagcctta acctgttgca tctgagaacg tgctttgtcc atcagacgaa caaacttagc
    10141 ccgcttatca acaggactcg cctccaattc caccaaacta ttttgcacta tacgcttaac
    10201 cagattacta gcaacagact tggtaatatt gagttcctgc tcgatatctt taatcaagac
    10261 caagtcttgg tttttctcgc gattatccaa aaaacgcaca acctgacctt gcggcccacc
    10321 cataaattca atgccgcaac gtttggcttc cttttgcacc atcaggtgaa tttgatgacc
    10381 aaaacgctta aagactaaca tcggtttacc cataatctcc cccttctaaa taaaaatagt
    10441 tctctggaga ataattaaat ttctatgaga actattttct tgattaaaaa aatcccaagt
    10501 gattttctca cttaggatca tgttctatag gttaaattaa aacccatcta cgttcgtata
    10561 aatcttttgg acgtcttcgt cgtcttcaag aacgctgtaa agtttttcaa aggtttcaag
    10621 gtcttcgcct gacaattcca cttctgactg aggaatcatt tccaattcag tcacttggaa
    10681 ttcttcaata ccagactcac ggagggcaac gatagccttg tgaaggtcag ttggcgctgt
    10741 gtaaactgtg attgtacctt cttgtgcttc tacgtcatcc acatccacat ccgcttcgag
    10801 caattgctca aagactgcgt ccgcatcttc acctccaaat acaataacac ctttgttgtc
    10861 aaagaggtaa gaaacagaac ctgaagcgcc catgtttccg ccgtttttac caaaggctgc
    10921 acggacattg gctgctgtac ggttgacgtt agaagtcaaa gtatccacaa ttagcataga
    10981 gccatttggc ccaaaacctt cgtaacgtcc ttctgtaaag gtttcgtctg tgtttccttt
    11041 ggctttatca atcgctttat cgataatgtg ttttggcact tgggcttgtt tagcacggtc
    11101 gataacgaat ttcaaagctg agtttgattc tggatctgga tcaccttttt tagctgctac
    11161 atagatttct acaccaaatt ttgcatatac tttagagttg gctccatctt tagccgtttt
    11221 cttggctacg atattggccc atttacgtcc cattaggaat ctcctttttt cacattttaa
    11281 tctttcttat tataacacaa gtttttttga ttttcactag aggaaatgga ttttattagc
    11341 aaatcaagct aggatagcac tttacctgct aagatggtct tgcctttcta tctttttatc
    11401 aacagacact catccacatt caaaaaacaa actagaccat tatctgcaaa tagaaagttt
    11461 cagccaagtt tgacaaagtc agctcaaatt actgtttgaa gtttgtagat ataagcgaca
    11521 aaaacaatca tactgcacct tttgttgaca gtctactcca gacatatcat agttcaagta
    11581 aatactttga aatccaacag ttcttatagg cgctattgta ttctaagaaa tcaatagaag
    11641 agtttctaag caaatctcta atactcaata aaaatcaaag agcaaactag aaagctagcc
    11701 tcaggttgct caaaacactg ttttgaggtt gcggataggg ctgacatggt ttgaagagat
    11761 tttcgaagag tataatttac gtgttcccaa gatggagaag ttagactagt acactggcac
    11821 ttctaaacca ttgctagcaa ttgatttgtt catatttaat ttcatttttt ccataaatgg
    11881 gtattagata taaacagcaa aatatttccg atacgtgtcg ttcttgaatt tccaatcatc
    11941 taaaacaagt aaaggataat caattccctg tatatcaagg aattggctac cctttttact
    12001 tttttacaca tcctgtttga tagactcatt ttaacatcac gagcatactc caatggaaat
    12061 cgctaggcaa gagataaact ttcagatatt cgcagagagc tcatcgcctc tttttgtcgc
    12121 aaacattctt ctctcctaat cattttctac cttatcctct acctgaggat agagagttgt
    12181 tccccaaata gaaatcgtcc gcttacgtac tagtggcaaa tcggtttttt cataaaccgt
    12241 acgccaccat tcccaggcaa gcccggtaca ctctctaatt ttgacagaga gattacgaac
    12301 attccctttt aaaggaatac tagtggtaaa gtgagccgtc aaatcctgcc catttctgtc
    12361 ccaagcctta ggagtcaaga cttccttacc ttgatgatca taggataatt catcccaagt
    12421 aatataatat tgggcaacat aggcaccact atgatccagc agtaaatctc cgtttctgta
    12481 agctgtaacc ttagtctcaa catagtctgt actgttttga aaggtcgcaa ctacattgtc
    12541 acgtaaaaaa gaagttgtat aggaaatcgg caagcctgga tgatctgctg taaagcgact
    12601 gccttcttga atcaagtcct ctaccatatc caccttgcct gttacaactc gggcacccga
    12661 acttgggtcg ccccctaaaa taaccgcctt cacttctgta ttgtccaaaa tctgcttcca
    12721 ctctgtctga ggagctacct tgactccttt tatcaaagct tcaaaagcag catctacttc
    12781 atcactctta ctcgtggttt ccaacttgag atagacttgg cgcccataag caacactcga
    12841 aatatagacc aaaggacgct ctgcagaaat tcctctctgt tttaaatcct ctaccgttac
    12901 agtatcttga aacacatctc ctggattttt aacagcatct acgctgactg tataataaat
    12961 ctgcttaaaa ttaacaatct gaatctgctt ttcgcctgaa tggacagagt taaaatcaat
    13021 atcaagagaa ttccctgtct tttcaaagtc agaaccaaac ttgaccttga gttgttccat
    13081 gctgtgagcc gtgatttttt catactgcat tctagctggg acattattga cctgaccata
    13141 atcttgatgc cacttagcca acaaatcgtt taccgctccg cgaacacttg aattgctggg
    13201 gtcttccact tggagaaagc tatcgctact tgccaaacca ggcaaatcaa tactataagt
    13261 catcggagca cgatcgaccg caagaagagt gggattattc tctaacaagg tctcatccac
    13321 tacgagaagt gctccaggat agaggcgact gtcgttggta gctgttacag aaatatcact
    13381 tgtatttgtc gacaagctcc gcttctttct ttcgataaca acaaactcat cgggtagctg
    13441 attaccctct ttgatgaaac gattttcaat actttctccc tgatgggtca agagtttctt
    13501 tttatcgtaa ttcatagcta gtataaagtc atttactgct ttatttgcca tcttctacct
    13561 cctaataagt tcctggattg agttgcataa actcagactt gttcagcgaa atcagccgtg
    13621 gttggactaa gtgatccaaa atttcctcgt acaattcttc tgagacattg cgtcgccgtc
    13681 tggctagata agaagtcgga ataaccgtat tatccaacat aaatacctta tctaagtcaa
    13741 tcaaggttgg tcttgtaaaa ggattacgag ctagatccgg ctcttctatc ataaagttct
    13801 tgaccaaacg tctggtcaag agagctggtt tgaaggtctg atttttaacc aactctttgt
    13861 ttttagtcat gctgttgtca atacagatat acatatgatt cttcacagcc aaatcgctac
    13921 taatagtcgg aaaaggcaaa taaagagcta caacatctcc tctcttaatc aagcaagagc
    13981 accccctttt ctcctaatgt aacatagaca ggattgacca agtcttctga ttgactcaga
    14041 atttccaaag tttgagtttg gcgcgctgtc aatttagtag catcttgtct cttcaataca
    14101 aaatgcttgt cgccaataac cttgacaata taatccttct ccaaagctga ctggtaaatc
    14161 cacatcagat gttgtctgtc ctgagaactc aagagagaag gattttcaag cctcccgata
    14221 gtctgataaa aatcaaaaac aggagctaac tcctgccaat ctgattggct agttgtcaag
    14281 gctagaaaaa gggctttgcg agctgatact tcttggttag ccttgagagt tactttcccc
    14341 tccaagtttt ttagaaatcg ggaaactcca gaaagcaaat ttttctctaa ctgcgagaaa
    14401 taaaaacctt tcgttcccag acataagtct ttcatgtcgc tttctctagc aaataagagc
    14461 tcaaacattt gatagtaaaa gaaaaatatc tggcactggg tcgcgctcat cttttcctta
    14521 tcggcttctt tttttaacca gagcaagggc gacaggtagc tggattgaga catttcctct
    14581 acctcctact cttttttaac tggagcatct gcactagctg ccacttcttt tgactggata
    14641 ctttcccact ggttaatctc ctctgagata agaccttcgc atgtcttgac aaatagggca
    14701 aaagccttgg tctttcctgc atatttctcc gtttggcatt gatagaggaa tttttctttc
    14761 tccaggagtt gcgcagtttt ttggtaagaa atccaatttt cctttgcatt atacaaattg
    14821 ataatcccct cacacagcaa gccgagactg gataaggcaa ccgaaatcaa acggtagcga
    14881 tcacctggca taggaatagc acaaaagaca gctatgagga aacctgccac gatttctgtt
    14941 atttttaata ccttatagcg cctacgatgt tgaacgcttt tctttaaaaa atgagctatc
    15001 tgtacgtcta atcgctctgt caggtacatt tcttctggcg tcatattcgt aactcctttc
    15061 atttactttg ataatcatag tataacatat ttgaatatca aagtatagta aaaactggac
    15121 tataacttat tagacttcct gcgaaacaaa atatggtata gtagttctat gaatgatgaa
    15181 gcaagtaaac aactaactga tgcacgattt aagcgtcttg ttggtgttca gcgtaccact
    15241 tttgaagaga tgttagctgg attaaaaaca gcttatcaaa aaagtcggac aagctggtaa
    15301 aatcttggct gacagtaatt atcaagggct catgaagata tatcctcaag cacaaactcc
    15361 acgtaaatcc agcaaactca agccactaac agttgaagat aaagcctgta accatgcgct
    15421 atccaaggag agaagcaagg ttgagaacat ctttgccaaa gtaaaaacgt ttaaaatgtt
    15481 ttcaacaacc tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt tgattgctgg
    15541 tattatcaat catgaactag gattctagtt ttgcaggaag tctattatat atgcacagac
    15601 atatgaaatc tttttgagac agcagttatg atatatttat ccattcacaa catcttctgt
    15661 actaatacta caatattggt acattttgat tacacaatcg tttcaaaaaa tatgatggaa
    15721 gcctgagtat tttatagtaa ttcccttcct atcaactaga tcaaccagtt gagtgttgaa
    15781 tgttgaaaca ccctagcctc agcaaaggac tatgatcagc atttcctagc caataggacg
    15841 ctccaaatca cctattctaa gtccatcact agcttggtca gtaagataca gactgcaagg
    15901 cgagactgat gtggttgatg agattttgga agagtattac aatcatagat tcaccagtag
    15961 acttgaccgc agatttaact atagtagatt gaaactagaa tagtacacct ctacttctaa
    16021 aacattgtta gaaatcgatt tgactgtcct gatcaatttg tcctgttctc gtttcatttt
    16081 actatactaa aaaaccacct gaaacaaatc aagtgactag aggataaaaa caaaaactgg
    16141 gcaaaaagtt ttgaaaagca aaaaacgcat aatatcaggt cttgaaaaac cttgatacta
    16201 tacgtttgat tgtgggaaga ttgacttcat tttctcctga aattgaagtt ttttctagtt
    16261 tccagatata gacgaattca atatagccat ctcgctacaa ttattttaac catcgagaaa
    16321 atttttcaga atttcaaaaa tttcattttg atccaatgaa atgtcattat tttgaagaat
    16381 agttgacttc acaggctcta attctatcac aaagcggtgc atgtctgctt ttaccgcact
    16441 acttgatgtt atagccgata acttttcatc tcctagcaag gaagctgtca aacgggtaag
    16501 gtcattcaaa tgctttttaa tggacttact taaaccttga gcacctgtgg cagagcgctc
    16561 cctcatatcc agccaagctt tagccttaaa aataattaat actcaatgaa aatcaaagag
    16621 caaactagga agctagctgc aggctgctca aaacactgtt ttgaggttgt agatggaagc
    16681 tgacgtggtt tgaagagatt ttcgaagagt atagaccaca attactcaat accgaatacc
    16741 cctgaatggt ttcttttaca tgcaccaata tattataata atcttcatcc aataataagg
    16801 ctgataaact agcatcttga tcaaaatata agggaatttc tcgaccgtcc ttctttaatg
    16861 gatattctgg taagatacta aatagttcaa tcatagaagg aaactcagga ttagttgttg
    16921 taaattgaaa aagctgcgct ttctcatctt tctgacttcc ttgatactct cccaattcta
    16981 aaaaatgatt caaggtagta taaaattcct tattttttac ttcatcaatg atgaccatat
    17041 cataatcttt tgttgtgcga cttttaaatc cttgcgaatc caatacgata gaggtagcag
    17101 ttcccccaat cagaacataa tagttctgaa aatccgcaaa catttcttga aaaataactt
    17161 tcgtattagc tggcatcatc ttctcccaga tactgtaata tcatattttc tagtgcttca
    17221 ctctcttcct ctatacgtgg gtcatcatca tcttttaagg tcaaataaag agaaatcgga
    17281 tctacaaatt gtttatcatg attattttta aaatcattcc aaaactcaga tacaaaagga
    17341 cgatatttcc atatctctag catctttcct tttaaaacat gctgagaaag tggcaaggat
    17401 aactgattga attttctctg ccatatgaca tagctaatat tttcatccgt ttcagctaaa
    17461 aaagttgaat gcgacaaagc ataagcacca ccatatagaa gattagaaac agattttatc
    17521 tgctttatat cgccatctgg caataaaatc cgttttttga tgggattaaa taaacatgac
    17581 acggatttta agaataattc tttctttgac accgtatatg tgtaaagctt attttgcttg
    17641 tttaaccaat ataaagcttt aaaagtcctc aaacacctac aaattgttga gtttggaagt
    17701 ccagtgactt gtgaaagcaa atcaacatct actacttttt gaccttttgt caataaaaag
    17761 gcaatccacg ttaattgttc gctaggtgtt aattccttag ggacttcagt atcattcgca
    17821 ttcagtacta gtcccaatgg agggaagaag aggtttccct taaagtctac aaacggaact
    17881 ctagcttgaa gtaattgctt tttttcactg tctgataact tcgaaaacac caaaacaaca
    17941 tccatattgg ctttttcacc catagtgcga gcctgagtaa caaatgaact caaactcccc
    18001 cttctctttt ctttaatcaa taaaaatgat tccttatgaa aagtcatttg agtatactca
    18061 aaccttttta caaaactgat tggtaaagtc aaagtcagtt cctcaatact gacatcaaca
    18121 taaaaggatt gaaaaattga cattatcttt ttgacattca tgttttttcc ttattctatc
    18181 atttttatta tattttatca ttcggtataa taaaatataa gttttttgat aaaataacca
    18241 aaaactactc gctatcccct ctcacattac cctacatatc gtttgacatg cgactgatag
    18301 ttcaggaaaa cttcaaggag aacttttctc tcatccacta tgcaggactt actatttcac
    18361 ttctactcct ataggctcaa tttgacactt ttctttttcg aattgctcat atgcctcctg
    18421 aatagtgagt tcgatttatc caaatttatt tttgtctatt ttgatgaata cttccacgaa
    18481 gatagtctga aaatgaattt gcaccaattt tccttctctt tttaagcata ttattccaga
    18541 tatgattgcc ctcttgttca gtaataaatt acgctttaaa cgcttcaatc agtatatctc
    18601 ctgttgtcat atgttctaaa gaaaattctt ctacatatgg tttaacatct cttaggttat
    18661 tacttcctaa tatcccatta tgctttttcg ctaagaaaat agaagtcgct tctcccttac
    18721 caataatctt gttactatca tgatttcttg ttaaatctct atataatgcg tattcttcag
    18781 ttccaatgtc tatgctcaca atctcagctg aacccttagt taccaactgg tctatcctag
    18841 attttaaatg gggaattgta ggtatattga tttcatcata cacctcttgt ggaataacaa
    18901 ttttacccga atagagcttt tctaaaagat gttcagtgcc aacctataaa aatgctgaaa
    18961 tacaatctgc atcaataaat acacgactag tcaaacgaca actccccctc ttcatctagc
    19021 ccatatacaa tatcatatct gaaagcatct agtaacagtt cctcatactt cccttgcgaa
    19081 attctgttat tttctaaaag ttgttcagtc gatttaatat agtgtcctaa taccatttcc
    19141 tttttacttt ctgacaaagg acgatataaa cttgtatcat agcctaatct tgaagctgtc
    19201 tctataacac taatatccat atttttaatt tcttctgcat caaggtatcc atcatttctc
    19261 aatctatata acatagcttt atgactgata ccataaaact gacccaattt tataatatct
    19321 tctacttcaa gatgagttct attggcattt tctctgattt cctcaaccat cctatacagt
    19381 gaagatggga aaattaaaaa ataagaagca aactgatccg cttttctttc agtttcatct
    19441 ccttcaccaa tcaagataag actgactgaa ctcttcttca cctcatcata ataaagatga
    19501 tacagtccat gtgctaaaga aaatctttac cttcctaatg gcatgtctga attgactgca
    19561 atgagactga actgagttcc tttataacag actccgctaa tattctttcc gagtccataa
    19621 aataccagcg tcaaattttc tatcttttgt accaatttaa aaatatctat cggcgattca
    19681 ccatcagctc ccaacttttt tctaagattt ggagctttat tacttaaatc cattcgtgat
    19741 attcctttca cctttttcca ttttggcaat catgctttga ttcaaagaca aatactcagc
    19801 aatcttatct tgagtaagat ttgaagatat tctaagttct tttattcttt ttccaacatc
    19861 acatacattt atcatattca tacacctctc ataaaaagaa tagcacactc ttgtcataat
    19921 tttttaaata aaaaaattat gacaaaacaa ggaagcaatt tattgatgct gcttaaaaat
    19981 ctaaaattga tgagttccta tcaaaaatcg tatcttcaac ctcaaaacag tacttaaagc
    20041 tatccgactc ggtttacatt gtcaaattta gattttattt gagcataact ttctagtttg
    20101 ctttctgatt tttgtttaat atagtagcaa acattgaagg aaatatctcc acaaaaaaac
    20161 gcatactatt aagctttttc aagacctaat aatatgcgct gttctgattt gaaagacatt
    20221 ccattattat tttactgtaa tcaagccatc tggctctact gtgaattctg gcttgtctgc
    20281 cagtgttccg tctggtttga ggtagtacca gcctgttccg tccgctgact ggataaaggc
    20341 atttgatacc atggcgcctt ctttagcgtc taagtagtac caagtgtcct tgtacttgac
    20401 ccagcctgtc ttcatggcac cttcttcgtt gaaatagtac cacttatcag cgattttctt
    20461 ccagcctgta gccatttcgc ctgagttgtc gaaccagtac cagttgccgt ctgtgtgctt
    20521 cctccagcgg tctgcaagca tatagcctga actgtcaaag taataccaag tgccattgat
    20581 tttctcaaac ttgtcttttg gataagagcc gtctgaatgt acgtaccagt agccagtgtc
    20641 attcttctgc cagcctgttt caatcgtcaa gccgttctca atatcatgtt taaactgctc
    20701 acggctaatg ccccatttag caagatatgg ataagggtca acgtggtctg agtggttgtt
    20761 tggttggtta ttcgtgcaat actcgtgcgt tttaattcca gctaaactcc ctgtatcaag
    20821 cgttttcggc aaacctgctt catctgctag attgcgtaag agttcgatat aaaggcggta
    20881 gtccgtcatg aactcttctt tggttgaatg gctttcaatc agttcaaccg ctgcataggt
    20941 ctcagcattc caaccgcccc caacgtccca ggcaccatta tcaacaggtc ctacctgcat
    21001 gatgcaaccg ttcccaacaa tgtgcgagaa aaaacctaat tctgggtctt tccgccagtg
    21061 ataatccgct tcattctgta cggttgaatg cggattccca gttgagtgtg cgtgtacttg
    21121 cctatatggt tgcacgccga cttgaggcaa atctgttctt aatttactca cattaatttc
    21181 catattctac tccttatcaa ttaaaacaac tcatttttta caatccagaa ccagaaactc
    21241 ctttatttct accttacaaa gaagacaatc ttagtcacga ttaggcttgt agatagaacc
    21301 tcaaaacgca ctattttgac actgtaaata ggactgacaa ggtctgcatt ctatctacaa
    21361 taacacccca gactaaaaag cttttcaaaa gtatattttt acagtctcta tatgtccttt
    21421 tcataaatac tatactttat tatatcatat aaaagaagtc aaaagtctgt taaactattt
    21481 tcaacaccaa actaaagaag agaacacaag ttttttcgat tttcactaga ggaaatggat
    21541 tttattcagt aaatccaact aggattgcac tttggttgcc aagattgcct tgccttcttt
    21601 tatcaaggga tgacggaata gtgagaagta cagttgaact gtcatggcaa cccagataag
    21661 aggttcacaa aggataacac ccttatatcc tgcccaagga ataatcaaaa ccacaaaaac
    21721 gatttttccg attagttcaa taaagctaga aactagagga aggatctttt gccccaagcc
    21781 ctgcaagcaa ttgcgataaa tcaacaagag gctcaaaatg ggataaaagg ctgaactgat
    21841 ttgcagatag agacttccat tttctatcaa gtaaccatct gtcgaactag ccaagaagga
    21901 aaccaaggct ggactggcaa aaaagaggaa aatacaaaca aaaactgccc aggatatact
    21961 taaacgactg ccgattcgaa gaccttgaac aatgcggtca ggtcgcttag ctcctagatt
    22021 ctgagaagca aaggtcgtca ttgatgcaga aatagcggtc ataggaagaa gggcaaaggt
    22081 cataatgcgt cgagctgccg tctgggcact aataatcact gcacccaatg tattaacaga
    22141 agactgtaaa atcacactgc cgatagatac aattgaactc atcaagccca tagccaaacc
    22201 ttgctccaag agatccacgt acaagctttt gttccatttg aaatgtttaa accgtggcaa
    22261 gagttctggc acacttttac gaatataata aaagcagaga accgctgata aaccttgtga
    22321 aataatagta gcaagtcctg cggattgaac tcccagatgc aattgcgtaa taaaatagag
    22381 atccagaacc acattaacca aggcagagaa aatcagaaat cccagggctg ctagactgtc
    22441 accaatagac cgcaacaagc ctgcaaaaag attataagca aagctgacac ctacacaggt
    22501 cacaatcata gaaatatatt gataagattg aggaagaatt tctgcaggag tatctaagta
    22561 ttgcaagaga ggatacaagc caagaaagcc cagcaacata actagaatgc tcaaaagagc
    22621 acctaaaatc caggtggctg ctactgcttc cttgatttta gtgaaattcc gagccccata
    22681 ataacgagca atgacaatcc ccatgccatt gccaacacca agtgtaaaac ctacaatcag
    22741 gtcaaaaatc gctgtcgtcg ctcctactgc agccaaggat tcttgaccaa gaaatcgtcc
    22801 aacaatcaag acatcagcag tgttatagag ctgttgaaaa atatttgata gcaagattgg
    22861 gaaggcgaag cttaagagcg agggaagaat cggaccatgt atcaggtcca ctgttcgttt
    22921 tttattcata aagctattat atcagcttcc tagaggagcg acaagaaaca gcaaactata
    22981 tatagcggaa tgaaataagg acagtcaaat cgatttttaa caatgtttta gaagtagatg
    23041 tgtactattc tagtttcgat ctattatagt tggttgagtt tggaatagta cgctgtagct
    23101 gctaaaacat ttctagaaat taatttgact ttcctaataa agttgttcat atcttatttc
    23161 aagctactat atataatcta aaaacttgaa tcaaaaatcg aaaaagtagt ggatttctcc
    23221 actgctttaa cagcttattc ttcaatttcg atttcaagtt catcgcctaa gtcaagcgta
    23281 acttcttcat tcactgcttc ttctttcttt ggctcatctt ttttgttttc agtatcttgt
    23341 tctgaaactt cttctccatc aatcaagcca aatttagaac ggacttgctt atcaatttca
    23401 tcaaagattt ctgggtgctc tgccaagtat ttcttagcat tctcagaacc ttgcccaatt
    23461 ttttcatctt tgtaagaata ccaagcccct gcttttttga taatatccaa atcgcttgca
    23521 atcttcaaaa gctcaccagt cttagaaatt ccttctccgt acataatttc aactacggct
    23581 tccttaaacg gtggagctac cttatttttt acaaccttaa tcttagtttc tttaccgaca
    23641 ttggtttctt tttgatcacc agttccctta atttgtgtat taccacgaac atctaagcgg
    23701 actgaagcat agaatttcaa agcacgtccg cccggtgttg tttctggatt tccaaacatc
    23761 actccaactt tttcacgcaa ttggttgata aaaatggcaa ttgttttggt tttattgata
    23821 gaggcgccaa gtttacgcat ggcctggctc atcatacgag cctgcaaacc aacatggcta
    23881 tctccgatat ctccatcaat ttccgcacga ggaacaaggg cagcaactga gtcgactacg
    23941 acaagatcaa ctgcacctga gtcaatcaat tttcccgcaa tctcaagacc ttgctctcct
    24001 gagtctggtt gagacaagag caattcgtca atattgacac caagggccgc agcataagct
    24061 ggatcaaggg catgttccgc atcgataaag gcagcaatcc caccttcttt ttgcgcttgt
    24121 gcaactgcat gaagggcaac cgttgtctta ccagatgact ctgggccata gatttcgatg
    24181 atacgtccct taggataacc acctgagcca agggcaatgt caagagctaa agaacctgag
    24241 ctcatcactt gcaccttttg ctccgcacgt tcacccaaac gcatgattga tcctttacca
    24301 aagtctttct caatcaattt aagagcgtca ttcaaggcct tttcacgttc tgccccaaat
    24361 ttttttgaaa tttcttctaa tttttttggt tttttcgcca ttctattctc ctacattcta
    24421 atgatcctca gacctatcta ctattatatc aaaagttagt cacttaataa agccttgcga
    24481 actaggttaa aggcatgcat aaccgcaatg tgacgtacat ctgctcggct tctgcctcca
    24541 atattaacct tgataacctc agttccttga tcttgcgcca agcctatgaa gactgtccca
    24601 actgggtgtc cttctaggct atctggtcct gccactccag tcaaactaat tccaaaatca
    24661 gactgggtct tgcttcgtgc ctgctcagcc atcttctgag ctgtaaattc agacaccaca
    24721 ccatgttctt ccaaattctt ggcaggaata tccaacatcc ttgatttttc ctccaagcta
    24781 taggtcacaa aaccaccctt aaatatactt gaaactccag aaaaattcgc cacggtagct
    24841 tggaaaagac ctgccgtcaa actctctgca gccgcgatgg ttttcccttg ccttttcagt
    24901 tcttctacca caatgctggc taaactagtt tcttccccat aaccatagca aaagtctcgt
    24961 aaagaaattc cttcgaaagt ctggcagtcc aagatttgat tttccaagat atccagcgct
    25021 tgattcgcct cttcttgact gctagccttt gttgacagac gtagagtgac ttctcctgtc
    25081 ttggcataag gggccaaggt aggatcgatc tgattatcaa ttaaatcagc caaaatcgta
    25141 accagctggc tctcgccaat cccaaagaaa cgaagaactc gggaatacag cttgctccct
    25201 gtcatcaact tgggtagaag ttggtttaag accatgggtt tcaattcact tggcggacct
    25261 ggaaggacga cataggtcac tccgtctact tctaattttc ctccaacagc cagtcctgtt
    25321 tcgtttggca gtggaatcgc tccttctaca atttgagctt gtctttcgtt attcggtgtt
    25381 cgggcatagt ctggtcgcag ggcaaaaaag atatccaact tctcctgagc ctgaggatca
    25441 aagactaatg ctttccctaa aaatttagct agggtttgtt tggttaggtc gtcctcagtt
    25501 ggccccaaac cgcctgtcaa aatcaccaga ctgctacgtt gactggcaat ctcaagcaaa
    25561 gacaagagac gaacttcatt gtctcctaca gccgtctgaa aatatacatc taccccaatc
    25621 tcagctagtt tttccgacaa aaactgggca ttggtgttga caatctgtcc tgtcaaaatc
    25681 tctgttccaa cagcaatgat ttctgctttc atgtttcctc ctacctatct attcgtattt
    25741 ttttgaaaaa atcgcaggaa ttttcctacg attgattttt ttatttgtat caaaagttaa
    25801 ttatcttcat caccaacagg tgctctgcca aataaatctt caaataaaac cgcattggtt
    25861 tcaagctgag taacttcttc ttgtcccaaa gaacgtcgga gtatattttg catttccaac
    25921 atatgtgctc tcgaaacaat ctggtaagaa acaccttgaa gtatctctcc ttcaccctgc
    25981 aactgctgag tttcaatggt tttaaatgaa tctttatagc ctagcaagtt agggatactt
    26041 tttgcagaca aatcaatatt ggtctgcata ttgtcactca aagcttttag aatctcttga
    26101 taatgaccaa cgctatttaa actgagagct ttttccatga ctttttgaat aacttcacgt
    26161 tgacgttttt gacgaccata atccccctca ggatcttggt aacgcattcg tgcatagact
    26221 agggcttctt ctcccccaat atgttgctcc ccaacaccga tagaaatggt attaaattct
    26281 tcttggtcac tgatagaaat tgggaaacct aggatattat tgactgtaat acctcctact
    26341 gcatccacta atttttgcaa ccctctcata ttgaccatca catagcgatc aatatggata
    26401 ttcatcattt tttgaatggt ttctatagca agctctgctc caccatctgc atatgctgag
    26461 ttcagtttcg cttcatgagc ctgaccattc cctgattcaa tgcgcgtcag aatatcccgc
    26521 tctaaactca tcattgttgt ttttttcgtt ttaggattca ctgtcatcaa gatcatgcta
    26581 tcacttctac cgacccaagt ttcagttcgt tcagcatttc cggtgtccac tcccattaac
    26641 agaatggtta gaggttcagt cgcttcaata accttggttt cttcgccgat ttttttatag
    26701 gttttagcta aggtttctgt cccttgttga taaatagtat aagcaaaaac acctactcct
    26761 actacagtta cagaaagtaa agctagcacc attccaataa tttttttaac catatttcta
    26821 ctaatctatc agtttaccca tcaagtaaac atcgataaat ttcccttctt ctatatatgc
    26881 cccacgctct tggctacctt caatgacaaa gccatgcttt tgataaagat ggactgctgc
    26941 ttgattacga gtttggacag tcagttggag acgacgcaga atgccacttg cttgtgccca
    27001 ctctatcgct tcttctagca acaaacttcc caagccatta ttccaatatc tttttccaat
    27061 cacaatgaag agatctccaa tatgacggac tctcttacgc tggtcagctg taatatttac
    27121 aataccagca attttgccat ttaagaatgc aagtaaggtt atctgattgt ccgaactagc
    27181 ttgcttgttg aggaatattt ccatctcctc actagtcaag agaataccat ctccgtctag
    27241 gctggtaaag tctgtctcca aactcacacg atttaaaaag gccactaatt cagctgcatc
    27301 tttgggctct gcttccctaa tgagcaattc atactccata ttgaagctcc tctaacaatt
    27361 tctcagcacg caaacccttt gcctgaaaat ttaaacggcg tccatctgct tcttttagaa
    27421 tttccaattc taaataagca tctggcaagg catctcctaa gagatttccc cactcaataa
    27481 cagtcacgcc gccaccaaag ataaactcat ccaagtcgat agaatcagca tctccttcaa
    27541 tacgataaac atctaggtga taaagtggaa gtcgaccttc atactctctc acgatagtat
    27601 aggtaggact tttaatcatt tgagaaatct gtaatccttt tgcaagtcct ttagtaaagg
    27661 tcgttttacc tgcacccagt tctccaatta agattaaaac atcattcttt gctaatagat
    27721 ggcccaaacg ctcccctaag gcttgcaact cttcttcatt ttttgtgtac atactcttat
    27781 tataccaaaa acttttcttt tgtgtctatt ttcctactaa acttatcatc ataacatcca
    27841 taaaaaacag gctttctcta aaagaaaatg agcgtaacaa tgaccaatac aagatctcgg
    27901 aaaatatgac cataaaagga aacttccttc ttaaccgaat ttgggacaag ataggctgca
    27961 aaaaacaagc ccagtccagt ataaatcaga agtgagacaa tggtcattgg atttcttaag
    28021 aaaagaagtg ttgctaaaat agtcaccaac actgtctttt ttctgtctag catagcaaga
    28081 aaatcgcgca cgtatttttt caagggtaaa aaaatcagca aatctagccc aaataggaaa
    28141 aagaaggatg gcaataaaaa gtcaactaat tcttgctgca gcgtattttt gatgaacaag
    28201 ttatctgaca aaacaagaac agctcctaac aaattaatta agagtaacat actgtaaaaa
    28261 agcttcaccg acttcttact ggctaggaca ctatggactt cttgcttacg ggtataaaga
    28321 taatttactc cagcacagat tcctgaaacg aaaaccatgc ttccgatgaa aaaagctgta
    28381 ctttgtttaa aggacaagat gcattccttc cataggaaac agctactcaa actgatttga
    28441 attaaagcta acaaaaataa gattctcatt gatttcatct tctctctccc ttcctaccaa
    28501 tcattatact aggagaaaag agagaactgt ttctaatctt ctcaaatgtc tctttaagac
    28561 gctaaacaaa cactagagac taatactcaa tgaaaatcaa agatcaaact aggtagctag
    28621 ccacaggttg ctcaaaacac tgttttgaga ttgcaaatag agctgacgtg atttgaagag
    28681 attttcgaag aatataaatt tgaaatcatg aaaatccgtc tagcgggtgt tttttttgtc
    28741 tcgcacctaa cggagcgaga cgaactaata gtcacataat cataaggctg atagtattca
    28801 tttcactatc agccttacag gttatttaac gtttcagaaa aactataatg tcaagattaa
    28861 ctaaacagta tctaattcct tcaaataatt ttctatcttc atcagcatta aaggattgtt
    28921 ataaatctta cataactctt ttgcttctat ataataattt ttgacttgtt ctctgtctag
    28981 aaatttggct ccagcatttc ctacaagaat aagtagagga gccagttggt agcttgtctg
    29041 tctttgttta cagagttcaa tcgtctcaag agcttcttgg atggcttcat tatatttttc
    29101 ctttgatact aggtagtgag cgtagttgta acgaactctg atgtagccaa ataaaaactc
    29161 ttgatggtcc aaattttttg tctgatacaa ctctattaaa tgagagtagt ttgcctcata
    29221 ttcttgttca cgacccacta aggaatagaa attagataga gtattcaacg cctttaaata
    29281 aatcagagta tttgaggaga cttttaataa tatattttcc aatgaagaaa ttgcttcaca
    29341 cttactgtca tattgataaa agtcaataat agctttaatc cattcaaggt aagttcggtc
    29401 ttctagtgtt agaaaagtac ttcgttcaat ctctattcta taaatatatt ccaaatcgtc
    29461 ataatttcta tcgtctaata gtcgagcaga caattgcttg aaattagaga ggttagattt
    29521 aatttcaatt tgttcattaa aaaaataatc taatggtact tcaagtcgtt gagagagttt
    29581 gaacaaaagg tctgcggagg gaatgaaatg ccctctctca attttactaa tctggctttg
    29641 ttcacaaatt ccttctgcaa gagtttgttg ggagagtctc aactcttttc ttttcaatct
    29701 gaatttctct gcgagtgtac tcattaaaga taat
//
LOCUS       DAVMAH010000029        29030 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVMAH010000029 DAVMAH010000000
VERSION     DAVMAH010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29030
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.029"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            16..1119
                     /locus_tag="VYO94_001189"
     CDS             16..1119
                     /locus_tag="VYO94_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HEV1759828.1"
                     /translation="MLLISTVLLPVRLKNNKILFINFNGKGYGDNPKSICEYLRTTYP
                     ELDLVWLTKETKGFPDGVRLVKYGSIRAFYEQASSKVWVYNVRAFARILKRKEQFYIQ
                     TWHGASSFKLIEKQAELPLNYVLEAKYDARVTDLMISDSKKQTEEYRKYFWYTGEILE
                     VGMPRNDSLFHCKDDYNKLENVRKELNISCDDFVILYAPTFRDNGDISYLNLDFLRLL
                     QSVEKGIRKNCKLLIRLHPNHSQFCRNILFNQDIINVTFFSDMQELILLADVLLTDYS
                     SSIFDFILLNKPYVRYVNDLEEYSKLRGLSDTYYELPDTIISTSEELYTLLPEKINDF
                     DYAAINQYRNGTLSPMFNGRASENIGRRIIQEL"
     gene            1155..2183
                     /locus_tag="VYO94_001190"
     CDS             1155..2183
                     /locus_tag="VYO94_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1759829.1"
                     /translation="MKNNVLKIGSGAIHQISSTLAQNNISGKILYCADPIVDNLYGSL
                     VRSQIEEIGRLKEESCNYNTIAYAMNIAERVIATDIDCIVGMGGGRVLDVCKYASYIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVNRGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLI
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSKRNLHGIQVALGTVAVLKIIEDP
                     ITPVTDYLQRFEVNINPKQMGIDEDLFVYCMQHATTMRNNRYTYLHEADLSTARVKQI
                     YKELVNEL"
     gene            2199..2903
                     /locus_tag="VYO94_001191"
     CDS             2199..2903
                     /locus_tag="VYO94_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="HEV1759830.1"
                     /translation="MKALILAAGLGTRLAPITNDVPKSLVPVNGKPILIKQIENLYQN
                     DVTDITIISGYKASVLKDVISGKYPEIKIIDNVDYKITNNMYSAYLGKDAMGSSEFLM
                     MNADVFYDASVIKSLLLHEAPNAIVTDLGTYIDESMKVVEKNGRLVEISKQISPEEAL
                     GASIDVYKFSPDAGACFFEKCREFIEDKNELQLWSEVALNAILQAVEFVACPLDGRWL
                     EIDNHEDLAAAEKLFA"
     gene            2924..3751
                     /locus_tag="VYO94_001192"
     CDS             2924..3751
                     /locus_tag="VYO94_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIA family hydrolase"
                     /protein_id="HEV1759831.1"
                     /translation="MINKVDYFGMDISDLKNKKLFLFDMDGTIYEEDRLFDGTLQLLE
                     YIQSIGGEYIFITNNSSKSVVDYIEKVNQLGIVAKRENFFTSAQATIVFIEEKYPHAK
                     VYCQGTKSLLKELSDSGIDVTDQVRDNIDLVLVGFDTELTSEKIRNTCEVLSTRDVPF
                     IATNPDVRCPVSFGFLPDCGSICEMISKSVDKTPIYIGKPEPTMVNIVRKKLNYSLSE
                     TVVIGDRLYTDIMTGINAGVSSVCVLTGEATADDIQQGSIKPTYTFRTVKEMWEGII"
     gene            3892..4761
                     /gene="rfbA"
                     /locus_tag="VYO94_001193"
     CDS             3892..4761
                     /gene="rfbA"
                     /locus_tag="VYO94_001193"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV1759832.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFLIGEEFIGDDSV
                     ALILGDNIYHGPGLSKMLQKAAQKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEK
                     PENPRSNYAVTGLYFYDNDVVEIAKGIKPSARGELEITDINKVYLNRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLELAQPLKKN
                     EYGQYLLRLIGEA"
     gene            4762..5355
                     /locus_tag="VYO94_001194"
     CDS             4762..5355
                     /locus_tag="VYO94_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV1759833.1"
                     /translation="MSDNFFGKTLAVRKVDAIPGLLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFVAGKLQNNVSFSRKNVLRGLHAEPWDKYISVADDGKVLGSWVDLREG
                     ETFGNVYQTEIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLAEAEVSEADKHHPLLRDVKPLTKDEL"
     gene            5367..6413
                     /gene="rfbB"
                     /locus_tag="VYO94_001195"
     CDS             5367..6413
                     /gene="rfbB"
                     /locus_tag="VYO94_001195"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV1759834.1"
                     /translation="MTEYKKIIVTGGAGFIGSNFVHYVYNNFPDVHVTVLDKLTYAGN
                     RANIEEILGDRVELVVGDIADAALVDKLAAEADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGLGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQPAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKETIKWYTDNQDWWKSEKE
                     AVEANYAKTQQVIK"
     gene            complement(6475..7329)
                     /gene="rfbD"
                     /locus_tag="VYO94_001196"
     CDS             complement(6475..7329)
                     /gene="rfbD"
                     /locus_tag="VYO94_001196"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV1759835.1"
                     /translation="MILITGANGQLGTELRYLLDERNVDYVAVDVTEMDITNSEMVEK
                     VFAEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTENVAKASEKYGAILVYISTD
                     YVFDGKKPVGQEWEVDDIPDPQTEYGRTKRMGEELVENLTSQHYIIRTAWVFGNYGKN
                     FVFTMQSLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYVTENQKEYGYYHLSNDAAEDT
                     TWYDFASEILKDSDVEVVPVDSSKFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALKE
                     FYKQEVRK"
     gene            7575..9557
                     /locus_tag="VYO94_001197"
     CDS             7575..9557
                     /locus_tag="VYO94_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1759836.1"
                     /translation="MKSSRLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGASEPILYKYLELQ
                     DKAITVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            9857..15160
                     /locus_tag="VYO94_001198"
     CDS             9857..15160
                     /locus_tag="VYO94_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1759837.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPTDLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPRAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HNPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDASTVEKPEFKLSSLASDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(15327..17486)
                     /locus_tag="VYO94_001199"
     CDS             complement(15327..17486)
                     /locus_tag="VYO94_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV1759838.1"
                     /translation="MNKPTILRLIKYLNISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(17483..18079)
                     /gene="recU"
                     /locus_tag="VYO94_001200"
     CDS             complement(17483..18079)
                     /gene="recU"
                     /locus_tag="VYO94_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV1759839.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            18145..18672
                     /locus_tag="VYO94_001201"
     CDS             18145..18672
                     /locus_tag="VYO94_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV1759840.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGTLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            18742..19071
                     /gene="gpsB"
                     /locus_tag="VYO94_001202"
     CDS             18742..19071
                     /gene="gpsB"
                     /locus_tag="VYO94_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV1759841.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            19092..19472
                     /gene="rnpB"
                     /locus_tag="VYO94_001203"
     ncRNA           19092..19472
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VYO94_001203"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            19557..20714
                     /locus_tag="VYO94_001204"
     CDS             19557..20714
                     /locus_tag="VYO94_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV1759842.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQFSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            20727..22121
                     /gene="mapZ"
                     /locus_tag="VYO94_001205"
     CDS             20727..22121
                     /gene="mapZ"
                     /locus_tag="VYO94_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV1759843.1"
                     /translation="MSKKRRNRHKKEAQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSDEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     PASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            22197..23621
                     /gene="gndA"
                     /locus_tag="VYO94_001206"
     CDS             22197..23621
                     /gene="gndA"
                     /locus_tag="VYO94_001206"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV1759844.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            23633..24322
                     /locus_tag="VYO94_001207"
     CDS             23633..24322
                     /locus_tag="VYO94_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1759845.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            24420..25385
                     /gene="cbpC"
                     /locus_tag="VYO94_001208"
     CDS             24420..25385
                     /gene="cbpC"
                     /locus_tag="VYO94_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV1759846.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWKYVRGKWYYLDNKNGDMKTGWYQDGSTWYYLDPS
                     NGDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            25404..26402
                     /gene="cbpJ"
                     /locus_tag="VYO94_001209"
     CDS             25404..26402
                     /gene="cbpJ"
                     /locus_tag="VYO94_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEV1759847.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKELEIKTQDSVGRKYGEKRENSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYIGGERRAGWINDASAWYYLDPATGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(26520..27752)
                     /locus_tag="VYO94_001210"
     CDS             complement(26520..27752)
                     /locus_tag="VYO94_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1759848.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEIVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTLFLVLSPFSLI
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(27911..28381)
                     /locus_tag="VYO94_001211"
     CDS             complement(27911..28381)
                     /locus_tag="VYO94_001211"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759849.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(28281..28619)
                     /locus_tag="VYO94_001212"
     CDS             complement(28281..28619)
                     /locus_tag="VYO94_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
                     /protein_id="HEV1759850.1"
                     /translation="MTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANV
                     TAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLKTFIHNSIWGNLSLFPTK
                     RYSQRKHFRL"
BASE COUNT         9071 a         5109 c         6440 g         8410 t
ORIGIN      
        1 gctagaacta tttttatgct attgataagt acagtgttat tacctgtcag gttaaaaaat
       61 aataagattc tatttattaa tttcaatggg aagggttatg gtgataatcc taaaagtatt
      121 tgcgagtacc taagaactac atatccagaa ttagatttag tatggctcac taaagaaaca
      181 aaagggtttc cagatggagt cagactagta aaatatggtt caattcgagc tttttacgaa
      241 caagctagtt caaaagtatg ggtgtataat gtgagggcgt ttgctaggat actaaaaaga
      301 aaagagcaat tttatattca gacttggcat ggtgcttcaa gttttaaact gatagaaaaa
      361 caggctgaat tacctttgaa ctatgttctg gaagctaaat atgatgcacg agtgacggat
      421 ttaatgattt cagacagtaa gaagcaaact gaggaataca gaaaatattt ttggtatact
      481 ggtgaaattc ttgaggtagg gatgccaaga aatgattcct tgtttcattg taaagacgat
      541 tataataagt tagaaaatgt tcgaaaagaa cttaatatct cctgtgatga ttttgtcatt
      601 ttatatgcac caacttttag agataatggt gatatatcct atttgaattt agattttcta
      661 cgcctgttac agagtgtgga aaaaggaatt agaaagaatt gtaaattatt aattaggttg
      721 catcctaacc actcacaatt ttgtagaaat attttattta atcaggatat aattaatgtt
      781 acattctttt cagatatgca ggaactcata ttgttggcag atgttctact aacagattat
      841 tcttcatcta tatttgattt tatactctta aataagccgt atgtaagata tgtgaatgat
      901 cttgaggaat attctaaact tagaggatta tcggatacat attatgagct acctgacact
      961 atcatttcga catcggagga actgtatacc ctcctgcctg aaaaaataaa tgattttgat
     1021 tatgctgcta taaatcaata tagaaatgga acccttagtc caatgtttaa tggaagagct
     1081 agtgaaaata taggaaggag aataattcaa gaattgtaaa gaaaatcatt gaattatttt
     1141 ttaggtgaaa aggtttgaaa aataatgtat taaaaatagg cagtggggct attcatcaaa
     1201 tatcctctac acttgctcaa aataatatat caggtaagat tctatattgt gctgatccaa
     1261 ttgttgacaa tctatatggc tctttagtta ggtcacaaat tgaggagata ggtcgattaa
     1321 aagaagaaag ttgtaattat aatacgattg cttacgcaat gaatatagcc gagcgagtta
     1381 ttgcaacaga tattgattgt attgtgggaa tgggaggtgg tcgcgtttta gatgtttgta
     1441 aatatgcatc ttatatttca aaacggccat atttatcaat tcccaccact gcagcgaatg
     1501 atgggatagc ttctccagta gcagttttga aaagacaaga tgatagacct aaaagtttgg
     1561 gtgcggcaat tccatctatg actcttatcg atattgatgt tattgcatca ggacccatac
     1621 agaatattaa agcgggcatt ggtgatacga tttcaaatta tacggcgttg aaagattggg
     1681 aattagctgt taaccgaggc aaggatgaaa tgcatggctt tgcctattta atgtcccaaa
     1741 actccttgga cgctttgatg aaaacaaagt ataattctat tacgcctgat ttcattgaag
     1801 ttttgataaa ttcattagtt ttatcaggta ttgcaatgga ttttgcagga agtagtagac
     1861 cagttagtgg ttcagaacac ttatttagtc atgccttgga ttattatggt tccaagagaa
     1921 accttcatgg tattcaggtt gcattaggta cagttgcagt attaaaaata attgaagatc
     1981 cgattacacc agtgacggat tacttgcaaa gatttgaggt aaatatcaat ccaaaacaaa
     2041 tgggaatcga tgaagaccta tttgtttatt gtatgcaaca tgctacaaca atgagaaata
     2101 atcgctatac atatcttcat gaagctgatt taagcacagc tagggtgaaa caaatatata
     2161 aagaattagt aaatgagttg tagaaaagag aggaaaaaat gaaagcactt attttagcag
     2221 caggtttagg aacacgtttg gctcctatca ctaatgacgt cccaaaatca ttagttcctg
     2281 ttaatggaaa acctattctt ataaaacaaa ttgaaaattt atatcaaaat gatgtaacag
     2341 atatcacaat tatttctggc tataaggcat cagtattaaa ggatgtaatt tccgggaaat
     2401 accctgaaat taagattatt gataatgttg attataaaat aacaaataat atgtactcag
     2461 cctatctagg taaagatgca atggggagta gtgaattctt aatgatgaat gcagatgtgt
     2521 tttatgatgc ttccgtcatt aaaagtttgt tacttcatga agctccgaac gcaattgtaa
     2581 ctgatttagg aacctacatt gatgaatcta tgaaagtcgt agaaaagaat ggtcgtttag
     2641 tagaaatttc taaacagatt tcacctgagg aggctttagg agcttctatt gatgtttata
     2701 aattttctcc tgatgcagga gcttgtttct ttgaaaaatg tagagagttc attgaagata
     2761 aaaatgagct tcaactgtgg agcgaggtcg cacttaatgc gattctccaa gctgttgaat
     2821 tcgtagcttg tccgctggat gggcgttggt tggaaattga caatcatgaa gatcttgctg
     2881 cagctgaaaa actatttgct taaaacaaat agggaggaca gatttgataa ataaagttga
     2941 ttattttggg atggatatca gtgacttaaa gaataaaaaa ttatttttat ttgatatgga
     3001 tggtaccatt tatgaagaag atagattgtt tgatgggaca cttcagttat tagaatatat
     3061 tcaaagtatt ggtggtgagt atatttttat tacgaacaat tcctcaaagt cagttgttga
     3121 ctatattgaa aaagttaacc aattaggtat tgtggctaaa cgggagaatt tttttacttc
     3181 tgctcaagca acgattgttt ttatcgagga aaaatatcct cacgcaaagg tgtattgtca
     3241 gggaacgaaa tcattgttaa aagaactatc cgattcggga atcgatgtta ccgatcaagt
     3301 gagagataac atagatcttg ttttagttgg ttttgataca gaactaacaa gtgagaaaat
     3361 ccgtaatacc tgtgaagttt tgtcaacgag agatgtccca ttcattgcca cgaatccaga
     3421 tgttcgttgc ccagtttcct ttggttttct tccagattgt ggttcgattt gcgaaatgat
     3481 tagcaaatca gttgataaaa ctcctattta tattggtaaa cctgaaccga cgatggttaa
     3541 catagttaga aaaaaattga attactcttt gtcagaaacg gttgtaatcg gtgatcgttt
     3601 atacaccgat atcatgacag gtattaatgc aggagtatcc tcagtatgtg tattaacagg
     3661 agaagcaaca gctgatgata ttcaacaagg gagtataaag cctacttata cttttagaac
     3721 tgtgaaagag atgtgggaag gaattatatg attctctagg ttattgattt ataaacttag
     3781 ggatatgacc ttgaaatgtt aatagcaatt tagtatggac aattaaaatt tactttcctc
     3841 ctagtggttt gtcaaagtaa aagacttatc aaaaaagaaa ggtacactat tatgaaaggt
     3901 attattcttg caggcggctc aggtacccgc ctgtacccac ttactcgggc tgcgtcaaaa
     3961 cagctgatgc cggtttatga taaacctatg atttattatc cgttgtcgac attaatgttg
     4021 gctggaatta aagatatttt gattatctca actcctcaag atttgccccg gtttaaggac
     4081 ttgctcttgg atggttccga atttgggatc aagctttctt atgcggaaca acctagtcca
     4141 gatggacttg ctcaggcttt tcttatcggt gaagaattta tcggtgacga tagtgttgcc
     4201 ttgattttgg gcgacaatat ctatcatgga cctggtttga gcaaaatgct tcaaaaggca
     4261 gcccagaaag agaaaggtgc aactgttttt ggctaccaag tgaaggatcc agagcgtttt
     4321 ggtgtggtcg agtttgatac agatatgaat gccatttcca tagaagaaaa accagagaat
     4381 cctcgatcca actatgccgt gaccggtctg tatttctatg ataatgatgt tgtagaaatt
     4441 gctaaaggta ttaaaccaag tgcacgtggc gagttagaaa ttacagatat caacaaggtt
     4501 tacctaaatc gtggtgacct ttctgttgag ctgatggggc gtggttttgc ctggttggat
     4561 acgggaaccc atgaaagcct gctagaagct tctcagtata ttgaaacggt tcagcgtatg
     4621 cagaatgttc aagttgcaaa cttggaagaa attgcctatc gcatgggcta tatcagtcgt
     4681 gaagatgtgc tcgagttggc gcaacctctg aagaagaatg aatacggaca atatttgctc
     4741 cgtttgattg gagaagcata gatgtcagat aatttttttg gaaagacact tgcggtacgc
     4801 aaggttgatg ctataccagg actgctagag tttgacattc ccgttcatgg agacaatcgt
     4861 ggttggttta aggaaaactt ccagaaggaa aagatgctac cgcttggttt tcctgaaagc
     4921 ttctttgttg cagggaaatt gcaaaacaac gtcagctttt ctcgaaaaaa tgttcttcga
     4981 ggattgcatg cagaaccttg ggacaagtat atctctgttg cagacgatgg gaaggtttta
     5041 ggatcttggg tggatttgcg tgaaggcgag acttttggaa atgtttacca gacagagatt
     5101 gatgctagca agggaatttt tgtccctcgt ggcgtcgcca atggtttcca agtcctctcg
     5161 gatacagttt cctatagcta tctggtcaat gactactggg ctcttgaact aaaacccaaa
     5221 tatgcctttg tcaactatgc tgacccatcc ttgggaattg agtgggaaaa tctagcggaa
     5281 gctgaggttt cagaggcaga caaacaccat cctctattaa gggatgtcaa accacttacg
     5341 aaagacgagt tgtaaaagga aacattatga ctgaatacaa aaaaattatc gtgacaggtg
     5401 gagctggttt tatcggttct aactttgtcc actatgttta caataacttt ccagatgtcc
     5461 atgtgacagt gctggacaag ctgacttatg caggtaatcg tgccaatatc gaggaaattt
     5521 taggcgaccg tgttgagttg gttgttggag atattgctga tgcagccttg gtagacaagt
     5581 tggcggctga agcggatgct atcgttcact atgcggcaga aagccacaat gataactcgc
     5641 tcaatgaccc gagtccattt atccacacca actttatcgg aacttacaca cttttagaag
     5701 cggctcgtaa atacgacatt cgtttccacc atgtatcgac tgatgaagtc tatggtgacc
     5761 tgcctctgcg tgaagatttg ccaggtcatg gggaaggcct aggtgagaaa tttaccgctg
     5821 aaaccaagta caatccaagc tcgccttact catcaaccaa ggctgcttca gacttgatcg
     5881 ttaaagcttg ggtgcgctca tttggtgtta aagcaacgat ttctaactgt tcaaacaact
     5941 atggtccata ccagcatatc gagaagttca ttccgcgcca gattacgaat atcttgagcg
     6001 gtatcaagcc aaaactctac ggagaaggta agaatgtgcg tgactggatt cacaccaatg
     6061 accattcatc aggcgtttgg acgattctga ccaagggtca aatcggtgaa acttacttga
     6121 tcggtgctga cggtgagaag aacaacaagg aagtgttaga gctcattctc aaggagatgg
     6181 ggcaacccgc tgacgcttat gaccatgtga ccgatcgagc tggtcacgac ttgcgttatg
     6241 cgattgatgc tagcaagctc cgtgatgagt tggggtggaa gccagagttt accaactttg
     6301 aagcaggcct caaagagacc atcaagtggt acacagataa ccaagactgg tggaaatctg
     6361 aaaaagaagc agtagaggct aactatgcta aaacgcaaca agtgattaaa taataagata
     6421 ctaaaaaagc aagagacctc gaggtctctt gcttttctag tatgtagtaa gcttttattt
     6481 tcttacttct tgtttataaa actctttaag ggcatcttgc caggttggga tgacgaaacc
     6541 tgttgccttt gcctttgcca aactcatagt tgagttgaga ggtcgtttag ccttagcggg
     6601 gaacttgcta gagtctactg gcactacttc aacatcactg tccttaagaa tctcgctagc
     6661 aaagtcatac caagtggtgt cttcagctgc gtcatttgat aagtgatagt agccatactc
     6721 tttttgattt tcagtcacat aggtcatgaa ttcggccaag gtccgtgtcc aagttgggcg
     6781 accgtattgg tcgttgacca ctgtgagcgt tttatgggtt ttggctaggc tttgcatggt
     6841 aaagacaaag ttttttccat aatttccaaa aacccaagca gtacgaatga tgtaatgctg
     6901 tgacgtaagg ttttcaacaa gttcttctcc cattcgcttg gtacgtccgt actctgtttg
     6961 cggatcaggt atgtcatcga cttcccactc ttgtcctact ggtttctttc catcaaagac
     7021 gtagtctgtt gagatataga ccagaatagc tccgtatttc tcagaggcct tggctacatt
     7081 ttcagttcca gttacgttga tggcaaaatc cagttctttc ccttcatctt cggctgcatc
     7141 aacagcagtg taggctgcac aatgatagac tagagttggc ttaacctcag caaagacttt
     7201 ttcaaccatt tcagaattag tgatatccat ttcggtcaca tccactgcaa catagtccac
     7261 atttcgctca tctagtaaat aacgtagttc ggtaccaagt tgaccatttg cacctgtaat
     7321 taagatcata tttttctcct tgatagttct tatacttaat tatatcaaaa atatagaaaa
     7381 atcggttttt agtgaaccct tttttggtat aaactttgtt agtgaagcgc aagagagccg
     7441 aatagttatt actttagaat atccttaaaa gtatttttca gaatttacca aattaattaa
     7501 aaaattcaga aaattatatt gacatctctc tgaaaagagt ctataataga gagaaagttt
     7561 taaaggagaa aatgatgaaa agttcaagac tacttgccct tgcgggcgtg acattattgg
     7621 cggcgactac tttagctgca tgctctggat caggttcaag cactaaaggt gagaagacat
     7681 tctcatacat ttatgagaca gaccctgata acctcaacta tttgacaact gctaaggctg
     7741 cgacagcaaa tattaccagt aacgtggttg atggtttgct agaaaatgat cgctacggga
     7801 actttgtgcc gtctatggct gaggattggt ctgtatccaa ggatggattg acttacactt
     7861 atactatccg taaggatgca aaatggtata cttctgaagg tgaagaatac gcggcagtca
     7921 aagctcaaga ctttgtaaca ggattaaaat atgctgctga taaaaaatca gatgctcttt
     7981 accttgttca agaatcaatc aaagggttgg atgcctatgt aaaaggggaa atcaaagatt
     8041 tctcacaagt aggaattaag gctctggatg aacagacagt tcagtacact ttgaacaaac
     8101 cagaaagctt ctggaattct aagacaacca tgggtgtgct tgcgccagtt aatgaagagt
     8161 ttttgaattc aaaaggagat gattttgcca aagctacgga tccaagtagt ctcttgtata
     8221 acggtcctta tttgttgaaa tccattgtga ccaaatcctc tgttgaattt gcgaaaaatc
     8281 cgaactactg ggataaggac aatgtgcatg ttgacaaagt taaattgtca ttctgggatg
     8341 gtcaagatac cagcaaacct gcagaaaact ttaaagatgg tagccttaca gcagctcgtc
     8401 tctatccaac aagtgcaagt ttcgcagagc ttgagaagag tatgaaggac aatattgtct
     8461 atactcaaca agactctatt acgtatctag ttggtacaaa tattgaccgt cagtcctata
     8521 aatacacatc taagaccagc gatgaacaaa aggcatcgac taaaaaggct ctcttaaaca
     8581 aggatttccg tcaggctatt gcctttggtt ttgatcgtac agcctatgcc tctcagttga
     8641 atggacaaac tggagcaagc aaaatcttac gtaatatctt tgtgccacca acatttgttc
     8701 aagcagatgg taaaaacttt ggcgatatgg tcaaagagaa attggtcact tatggggatg
     8761 aatggaagga tgttaatctt gcagattctc aggatggtct ttacaatcca gaaaaagcca
     8821 aggctgaatt tgctaaagct aaatcagcct tacaagcaga aggtgtgact ttcccaattc
     8881 atttggatat gccagttgac cagacagcaa ctacaaaagt tcagcgcgtc caatctatga
     8941 aacaatcctt ggaagcaact ttaggagctg ataatgtcat tattgatatc caacaactac
     9001 aaaaagacga agtaaacaat attacatatt ttgctgaaaa tgctgctggc gaagactggg
     9061 atttatcaga taatgtcggt tggggtccag actttgccga tccatcaacc taccttgata
     9121 tcatcaaacc atctgtagga gaaagtacta aaacatattt agggtttgac tcaggggaag
     9181 ataatgtagc tgctaaaaaa gtaggtctat atgactacga aaaattggtc actgaggctg
     9241 gtgatgaggc tacagatgtt gctaaacgct atgataaata cgctgcagcc caagcttggt
     9301 tgacagatag tgctttgatt attccaacta catctcgtac agggcgccca atcttgtcta
     9361 agatggtacc atttacaata ccatttgcat tgtcaggaaa taaaggtgca agtgaaccaa
     9421 tcttgtataa atacttggaa cttcaagaca aggcaatcac tgtagatgaa taccaaaaag
     9481 ctcaggaaaa atggatgaaa gaaaaagaag agtctaataa aaaggctcaa gaagatctcg
     9541 caaaacatgt gaaataactg ttgcaaaata taagaaagga tttagtattt ctcttgaatg
     9601 ctgaatcctt tttatatttg taaagaaaga ttctaaatgt actgaccccc aaaagttgga
     9661 gcctcttttt gtcagaatag agaaaatttt tgttaatttt acttgtttcc tattgctttc
     9721 tcagctatta tttgttatat taaaagcata attatttttt atttatcagg gttaagcatt
     9781 gcactttcag aggaaggagt attttttaaa aagaaaatgt aaacgcttgc tcaaaaatga
     9841 aaggatttag aagtttatga ataaaggatt atttgaaaaa cgttgtaaat atagtattcg
     9901 gaaattttca ttaggtgttg cttctgttat gattggagct gcattctttg ggacaagtcc
     9961 ggttcttgca gatagcgtgc agtctggttc cacggcgaac ttaccaactg atttagctac
    10021 tgctcttgca acagcaaaag agaatgatgg gcgtgatttt gaagcgccta aggtgggaga
    10081 agaccaaggt tctccagaag ttacagatgg acctaagaca gaagaagaac tattagcact
    10141 tgaaaaagaa aaaccggctg aagaaaaacc aaaagaggat aaacctgcag ctgctaaacc
    10201 tgaaacacct aagacggtaa cccctgaatg gcaaacggta gagaaaaaag aacaacaggg
    10261 aacagtcact atccgagaag aaaaaggtgt ccgctacaac caactatcct caactgctca
    10321 aaatgataac gcaggcaaac cagccctgtt tgaaaagaag ggcttgaccg ttgatgccaa
    10381 tggaaatgca actgttgatt taaccttcaa agaagattct gaaaagggca aatcacgctt
    10441 tggtgtcttc ttgaaattta aagataccaa taataatgtt tttgtcggtt atgacaagga
    10501 tggctggttc tgggagtata aatctccaac aactagcact tggtatagag gtagtcgtgt
    10561 tgctgctcct gaaacaggat caacaaaccg tctctctatc actctcaagt cagacggtca
    10621 gctaaatgcc agcaataacg atgtcaatct ctttgacaca gtgactctac cagctgcggt
    10681 caatgaccat cttaaaaatg agaagaagat tcttctcaag gcgggctctt atgacgatga
    10741 gcgaacagtt gttagcgtta aaacggataa ccaagagggg gtaaaaacag aggatacccc
    10801 tgctgaaaaa gaaacaggtc cggttgttga cgatagcaag gtgacttatg acacgattca
    10861 gtctaaggtc ctcaaagcag tgattgacca agccttccct cgtgtcaagg aatacagctt
    10921 gaatggacat actttgccag gacaggtgca acagttcaac caagtcttta tcaataacca
    10981 ccgaatcacc cctgaagtca cttataagaa aatcaatgag acaacagcag agtacttgat
    11041 gaagcttcgc gatgatgctc acttaatcaa tgcggaaatg acagtacgct tgcaagttgt
    11101 ggacaatcaa ttgcactttg atgtgaccaa gattgtcaac cacaatcaag tcactccagg
    11161 tcaaaagatc gatgacgaaa gaaaactact ttcttctatt agtttcctcg gcaatgcttt
    11221 agtctctgtt tctagtgatc aaactggtgc taagtttgat ggggcaacca tgtcaaacaa
    11281 tacgcatgtc agcggagatg atcatatcga tgtaaccaat ccaatgaaag acctagccaa
    11341 gggttacatg tatggatttg tttctacaga taagcttgct gctggtgttt ggagtaactc
    11401 tcaaaacagc tatggtggtg gttcgaatga ctggactcgt ttgacagctt ataaagaaac
    11461 agtcggaaat gccaactatg taggaatcca cagctctgaa tggcaatggg aaaaagctta
    11521 taagggcatt gttttcccag aatacacgaa ggaacttcca agggctaagg ttgttatcac
    11581 tgaagatgcc aatgcagaca agaaagtcga ttggcaggat ggtgccattg cttatcgtag
    11641 cattatgaac aaccctcaag gttgggaaaa agttaaggat atcacagctt accgtatcgc
    11701 gatgaacttt ggttctcaag cacaaaaccc attccttatg accttggatg gtatcaagaa
    11761 aatcaatctc cacacagatg gtcttgggca aggtgttctc cttaaaggat atggtagcga
    11821 aggccatgac tctggtcact tgaactatgc tgatattggt aagcgtatcg gtggtgtcga
    11881 agacttcaag accctaattg agaaggctaa gaaatatgga gctcatctag gtatccacgt
    11941 taacgcttca gaaacttatc ctgagtctaa atacttcaat gaaaaaattc tccgtaagaa
    12001 tccagatgga agctatagct atggttggaa ctggctagat caaggtatca acattgatgc
    12061 tgcctatgac ctagctcatg gtcgtttggc acgttgggaa gatttgaaga aaaaacttgg
    12121 tgacggtctc gactttatct atgtggacgt ttggggtaat ggtcaatcag gtgataacgg
    12181 tgcctgggct acccacgttc ttgctaaaga aattaacaaa caaggctggc gctttgcgat
    12241 cgagtggggc catggtggtg agtacgactc taccttccat cactgggcag ctgacttgac
    12301 ctacggtggc tacaccaata aaggtatcaa cagtgccatc acccgcttta tccgtaacca
    12361 ccaaaaagat gcttgggttg gggactacag aagttatggt ggtgcagcca actatccact
    12421 gctaggtggc tacagcatga aagactttga aggctggcaa ggaagaagtg actacaatgg
    12481 ctatgtaacc aacttatttg cccatgacgt catgaccaag tatttccaac acttcactgt
    12541 aagcaaatgg gaaaatggta caccggtgac tatgaccgat aacggtagca cctataaatg
    12601 gactccagaa atgcgagtgg aattggtaga tgctgacaat aataaagtag ttgtaactcg
    12661 taagtcaaat gatgtcaata gtccacaata tcgcgaacgt acagtaacgc tcaacggacg
    12721 tgtcatccaa gatggttcag cttacttgac tccttggaac tgggatgcaa atggtaagaa
    12781 actttctact gataaggaaa agatgtacta cttcaatacg caggccggtg caacaacttg
    12841 gacccttcca agcgattggg caaagagcaa ggtttacctt tacaagctaa ctgaccaagg
    12901 taagacagaa gagcaagaac taactgtaaa agatggtaaa attactctag atcttctagc
    12961 aaatcaacca tacgttctct atcgttcgaa acaaaccaat cctgaaatgt catggagcga
    13021 aggcatgcac atctatgacc aaggatttaa tagtggaacc ttgaaacact ggaccatttc
    13081 tggtgatgct tctaaggcag aaattgtcaa gtctcaaggg gcaaacgata tgcttcgtat
    13141 tcaaggaaac aaagaaaaag ttagtctcac tcagaaatta actggcttga aaccaaatac
    13201 taagtatgcc gtttatgtcg gtgtcgataa ccgtagtaat gccaaggcaa gtatcactgt
    13261 gaatactggt gaaaaagaag tgactactta taccaataag tctctcgccc tcaactatgt
    13321 taaggcctac gctcacaata cacgtcgtga caatgctaca gttgacgata caagttactt
    13381 ccaaaacatg tacgccttct ttacaactgg atcggacgta tcaaatgtta ctctgacatt
    13441 gagtcgtgaa gctggtgatc aagcaactta ctttgatgaa attcgtacct ttgaaaacaa
    13501 ttcaagcatg tacggagaca agcatgatac aggtaaaggc accttcaagc aagactttga
    13561 aaatgttgct cagggtatct tcccatttgt agtgggtggt gtcgaaggtg ttgaagataa
    13621 ccgcactcac ttgtctgaaa aacacaatcc atatacacaa cgtggttgga atggtaagaa
    13681 agtcgatgat gttatcgaag gaaattggtc actcaagaca aatggactag tgagccgtcg
    13741 taacttggtt taccaaacca tcccacaaaa cttccgtttt gaagcaggta agacctaccg
    13801 tgtaaccttt gaatacgaag caggatcaga caatacctat gcttttgtag tcggtaaggg
    13861 agaattccag tcaggtcgtc gtggtactca agcaagcaac ttggaaatgc atgaattgcc
    13921 aaatacttgg acagattcta agaaagccaa gaaggcaacc ttccttgtga caggtgcaga
    13981 aacaggcgat acttgggtag gtatctactc aactggaaat gcaagtaata ctcgtggtga
    14041 ttctggtgga aatgccaact tccgtggtta taacgacttc atgatggata atcttcaaat
    14101 cgaagaaatt accctaacag gtaagatgtt gacagaaaat gctctgaaga actacttgcc
    14161 aacggttgcc atgactaact acaccaaaga gtctatggat gctttgaaag aggcggtctt
    14221 taacctcagt caggccgatg atgatatcag tgtggaagaa gcgcgtgcag agattgctaa
    14281 gattgaagcc ttgaagaatg ctttggttca gaagaaaacg gctttggtag cagatgactt
    14341 tgcaagtctt acagctcctg ctcaggctca agaaggtctt gcaaatgcct ttgatggaaa
    14401 cttatctagt ttatggcata catcatgggg cggaggagat gtaggcaagc ctgcaaccat
    14461 ggtcttgaaa gaagcaactg aaatcactgg acttcgttat gttccacgtg gatcaggttc
    14521 aaatggtaac ttgcgtgatg tgaaacttgt tgtgacagat gagtctggca aggagcatac
    14581 ctttactgca actgattggc cagataacaa taagccaaaa gacattgatt ttggtaagac
    14641 aattaaggct aagaaaattg tccttacagg tactaagact tacggagatg gtggcgataa
    14701 ataccaatct gcagcggaac tcatctttac tcgtccacag gtagcagaaa cacctcttga
    14761 cttgtcaggc tatgaagcgg ctttggctaa ggctcagaaa ttaacagaca aagacaatca
    14821 agaggaagta gctagcgttc aggcaagcat gaaatatgcg acggataacc atctcttgac
    14881 ggaaagaatg gtggaatact ttgcagatta tctcaaccaa ttaaaagatt ctgctacgaa
    14941 accagatgct tcaactgtag agaaacctga gtttaaactt agctctttag cttccgatca
    15001 aggtaagacg ccagattata agcaagaaat agctagacca gaaacacctg aacaaatctt
    15061 gccagcaaca ggtgagagtc aatctgacac agccctcttc ctagcaggtg ttagtctagc
    15121 cctatctgct ctctttgtag taaaaacgaa gaaagactag tatttagtaa aacctcttaa
    15181 caagattacg gaagcagtct ctatcttttc caatgaggtt tatagtacag aaaaagcctg
    15241 agaagatgtc ttctcaggct tttgttaagc acataaatac aatagtgcta tgacaaaatc
    15301 acccagaaaa atctgggtga taaatgttat ggttgtgctg gttgaggatt ctgattttgt
    15361 tgatcagggg ttgtatttga ttgttgcgta ttattgttag gattggtagt cgtactatta
    15421 tttgtgcttg gagtggttga gctagactgt gaagttgaac tatctgatga tgagcttgaa
    15481 ctttcagttg atgggggttg ttgtggagca ggtgagctcc acgtagaacg agcaccattt
    15541 ttaaatacga attctccatt tctgtagagc ccctctggta tattccaatc ctctggattg
    15601 cttccttcag acaggtaggt catcatagag cggtaaactt tggcagcgac cgtaaggcca
    15661 ttgcctacaa gtggtgtcag acggttagaa tagcctgtcc atacagccat tgaatattta
    15721 cgcgtatagc cagcaaatag ttcatcaggt gctacaaatt gagaggtctt gatgtggttt
    15781 tcaatttcct cgtctgtata gttagaggtt cctgttttac cagcctgagg gagccaagca
    15841 agataggcat ttcgtccagt tccataactc aagactgttt tcatcatgtc ggtcatcata
    15901 taggctgtcg tttccttcat ggcacgagtt ccgacattag agaactcttt ttcactccca
    15961 tcactaaaga cgactttatg gatatacatt ggtttatagt aagttccacc atttgcaaag
    16021 gcagcgtaag cagcagccat cttttcacta cttgctccat attttttgtc tgattcggtt
    16081 gtgttacttg aaatggcatt tgagtagtga atacttgggt agtcgattcc gagaccattt
    16141 aggaaagtct tggcgcggtt gagtccgacc ttgtttagag tttccacggc tgggacgttt
    16201 cgcgattgtt gcagggcgta ttgcaaggtg atgttgccaa agtagcccct atcccagtta
    16261 taaacagggg tatttgtccc agggtagtta tagggctcat cgtgaacgat agtagcagtt
    16321 gaatcgtaga taccgtactc caaggcagga gcatagtctg tgatcggttt catagttgat
    16381 ccccagtcgc ggtttgtttc tactgcttgg ttaattccga aggaaacatt acttgactga
    16441 tggcgtgctc ctagctgggc aatgacttta ccgttagaaa catcaacgat ggtagaagcg
    16501 acttgcaatt catcgtctgg ataggcaacg tattcgtctg tattgtaaat atcccacaga
    16561 tgtttttgag cttcttggtc tacatttgtg tagacatcca tcccagttgt gagcaggtta
    16621 tagcctgttt cttcttcaac ttgattgatg acttccttga ggtaattatc catgtaagca
    16681 gggtaattac ttgctgattt gagactttgt agtccatcag taattggtgt attgactgct
    16741 ttctcatact gttcagcaga gatgtagcct tgatttttca tttcagataa gaccaagttt
    16801 cggcggtctt gggctgcttc tggatgtgaa taggggtcat attggtttgg tgcctgaggc
    16861 attccagcca gcaaggctaa ctgaggtaaa cttaaattat tgaggtcttt accatagtag
    16921 ttttgagctg ctgtctgcat tccatagttc ccattagaca tgtagacctt atttatatag
    16981 taggtcaaga tttcttgctt ggttgctttt tgttctaact gaatcgctaa ccaagcttcc
    17041 tgagccttac gagaaatagt ctggtcggaa gtcgaagttg aaaagtaagt caacttaatc
    17101 aactgttgag tgagagttga tccaccttgg agggaattgc tttgcagatt gcgcaagaaa
    17161 gctcccagga tacggatggt atcaatcccc ctgtggtcga agaagcgatg gtcttcgata
    17221 gaaacgattg ccttaaccaa atctgtggga atatcattag cttgggcatt gacgcggcgt
    17281 tcagaaccca agtcagcaat gagttgattt ttattgtcgt agattttact agaagttgtt
    17341 gcaactagtt tactctcgga taggctagga gccttgctaa cgtagtagaa aaaaactcct
    17401 ccgcctaaga caatggctgc gataaccaag cttaagaagc taatgttcag atacttgatt
    17461 aggcgcagaa tcgttggttt gttcatcttg ttttaccacc taataaatgt tctttgataa
    17521 cattgagata aggaatttga gggaaggcac cagccttgat ttcatatcca tattctcgaa
    17581 tatattcaag tggcattgat ttttgtccct tatcttgatg atagaagcga atcaaatcga
    17641 atgccggcaa taagtaggtt tcttgctgag aagaaaagtg aagaaggaca aagcagattc
    17701 cttgttgggc aaggacttgt tccatatgct gaatctgatg tggatgaaaa tttttcatcg
    17761 gaatcgcacg tttttgtttt gtttccttga cttcaaagtc gatgtaatat ccattataaa
    17821 cgccagaata gtccgtcgtt gaagcttgtc gaaaataggc ttcaacaatc ttggcacgac
    17881 ttcgttgtgg atagtccact tgtacgattt gaataggagt tggtttctta tgtataacag
    17941 ccaagccctg agacaaatag tagtcgttgg tagcattgat catcttttca aaagacattc
    18001 ctcgatttgc gaaatttttg ggttgagaaa gagatgtttg tcttttttgt gatgaaactt
    18061 tatgtggata gttgaccata attctcctta ttggtacaat aacatcactt tattatacca
    18121 taatttgcac agaaagggtt aaaaatggct acagctttgg ttttaggcta ttctgctttt
    18181 gatttgggtt tattttctga taaggatcct cgtcttaaat tgattaaaaa agcgatacgt
    18241 aaagatttag aggctatggc agcagatggg gtgtcttggc ttgtgtttac agggactttg
    18301 ggctttgaat attgggtttt agaggttgct caggagatga aaaccgaata cggtttccag
    18361 ttggccacca tttttgcttt tgaaacccat ggggaaaatt ggaatgaagg caatcagatg
    18421 aaactgagtc gctttaagca ggtagacttt gtcaaatatg cctatcctcg ctatgaacac
    18481 aaggggcagt taagagatta ccagcagttt ttgctggaaa acacgactag ttcctatctt
    18541 ttttatgatg aagaaaatga aacaaaacta gcttattttt accaaaagat gaaaaatcaa
    18601 gaggactatt ttataaagag attaacattt gatgaattaa atgaacttgc tgaaaatttt
    18661 tccgaaaatt gaagctttga ccttgatttt tgtttgcctt tttttatata ataatactag
    18721 caagcgagaa tggagagaga catggcaagt attatttttt cagcgaaaga tatttttgaa
    18781 caagagtttg gacgtgaagt ccgtggctat aataaagtag aagttgacga gtttttagac
    18841 gatgtcatca aggactatga aacctatgct gccttggtca agtcacttcg tcaggaaatt
    18901 gcggatttga aggaagaatt aactcgtaaa ccgaaacctt caccagttca agcagaaccc
    18961 cttgaagcgg caattacaag ttctatgacg aattttgata ttttgaaacg cctgaataga
    19021 ttggaaaaag aagtttttgg taaacaaatt ttagataact cagattttta agtagttatt
    19081 tgagatgtgc aatttttgga taatcgcgtg aggagaattg cttctcatga ggaaagtcca
    19141 tgctagcaca ggctgtgatg cctgtagtgt ttgtgctagg cgaaaccata agcctaggga
    19201 cgagaaatcg ttacggcagt tgaaatggct aagtccttgg ataggccaga gtaggcttga
    19261 aagtgccaca gtgacggagt ctttctggaa acagagagag tggaacgcgg taaacccctc
    19321 aagctagcaa cccaaatttt ggtcggggca tggagtacgc ggaaacgaac gtagtattct
    19381 gactgctatc agctagagct gttagtggta gacagatgat tatcgaagga agtggtccta
    19441 gtcacttctg gaacaaaaca tggcttatag aaaattgcat ataggttggg gctgagaaat
    19501 tttctcaacc tcatttttta aagtggacat atagaaaggt cttgcaagac tgtaacatga
    19561 aaaaagaatt taatttaatt gcaactgtgg cagcagggct tgaggctgtc gttggtcgtg
    19621 aagtgcgaga gttgggctac gattgtcagg ttgaaaatgg acgtgttcgt tttcaaggag
    19681 acgtgagagc tattatcgaa accaaccttt ggcttcgggc agcagatcgt atcaaaatta
    19741 tcgtaggaac gttcccagct aagacttttg aagagctatt tcagggagtt ttcgctttag
    19801 attgggaaaa ttatttacca cttggagctc ggttcccgat ttcaaaagct aaatgtgtta
    19861 agtccaaact tcacaatgag cccagtgttc aggctatttc taagaaagct gttgtcaaga
    19921 aattgcagaa acactatgct cgcccagaag gggttcctct gatggagaat ggcccagagt
    19981 ttaagattga ggtctctatt ctcaaagatg tggcaactgt catgattgat acgaccgggt
    20041 ctagcctctt taaacgtggt tatcgtaccg aaaaaggtgg cgctcctatc aaggaaaata
    20101 tggcagcagc cattttacaa ttttctaact ggtatccaga caagcctttg attgatccga
    20161 cctgtggttc ggggactttc tgtattgagg cagttatgat tgctagaaag atggcgccag
    20221 gtcttcgtcg ctcttttgca tttgaggaat ggaactggat cagcgatcgc ttgattcaag
    20281 aagtgcgcac agaagcggct aaaaaagtag aacgtgagct tgagctggat atcatgggct
    20341 gtgatattga tgctcgcatg gtggaaattg ctaaggccaa tgctcaggca gctggtgttg
    20401 caggagacat tacttttaag cagatgcgcg tgcaggattt acgttccgat aaaatcaatg
    20461 gagtaatcat ttccaatccg ccttatggtg aacgtttgtc agatgatgca ggggtgacca
    20521 agctctatgc tgagatgggg caagtatttg caccgctgaa aacttggagc aaatttatcc
    20581 tgactagtga tgaagctttt gaaagcaagt atggtagcca agcagataag aagcgtaagt
    20641 tatacaacgg aaccttgaaa gtggatctat atcaatattt tggtcagcgt gtcaaacggc
    20701 aagaggtaaa atagaaaggg atactcatga gtaaaaaaag acgaaatcgt cataaaaaag
    20761 aagctcaaga accgcaattt gattttgatg aagcaaaaga gctaacagtt ggtcaagcta
    20821 ttcgtaaaaa tgaagaagtg gaagcaggag tcttgcctga ggattccatt ttggacaagt
    20881 atgttaagca acacagagat gaaattgagg cggataagtt tgcgactcgt caatacaaaa
    20941 aagaggagtt cgttgaaact cagagtctgg atgatttaat tcaagagatg cgtgaggctg
    21001 tagagaagtc agaagcttct tcggatgaag ttccatcttc tgaagacatc ttactaccct
    21061 tgcctctgga cgatgaggag caaggcttgg atcctctatt gctagatgat gaaaatccaa
    21121 cagaaatgac tgaagaagtg gaagaggagc aaaacctttc tcgtctggat caagaggact
    21181 cagaaaagaa aagtaaaaaa ggctttattt tgaccgtttt ggcgcttgta tcagtaatta
    21241 tttgtgtcag tgcttattat gtctaccgtc aagtggctcg ttcgaccaag gaaattgaaa
    21301 cttctcaatc aactacagcc aatcaatcgg atgtggatga ttttaataca ctttatgacg
    21361 ccttttacac agatagcaat aaaacggctt tgaaaaatag ccagtttgat aaactgagtc
    21421 aactcaaaac cttgcttgat aaactggaag gtagtcgtga acatacgctt gccaaatcta
    21481 aatatgatag tctagcaacg caaatcaagg ctattcaaga tgtcaatgca caatttgaaa
    21541 aatcagctat tgtggatggt gtgttggata ccaatgccaa agccaaatcg gatgctaaat
    21601 ttacagatat taaaactgga aatacggagc ttgataaagt gctagataag gctatcagtc
    21661 ttggtaagag ccagcaaaca agtacttcta gctcaagttc aagtcaaact agcagctcaa
    21721 gttcaagtcc agcaagctca aatacgacaa gtgagccaaa accaagtagt tcaaatgaga
    21781 ctagaagtag tcgcagtgaa gtcaatatgg gtctctcgag tgcaggggtt gctgttcaaa
    21841 gaagtgccag tcgtgttgcc tataatcagt ctgctattga tgatagtaat aactctgcct
    21901 gggattttgc ggatggtgtc ttggaacaaa ttctagcgac ttcacgttca cgtggctata
    21961 tcactggaga ccaatatatc cttgaacgtg tcaatatcgt taacggcaat ggttattaca
    22021 acctctataa gccagatgga acctatctct ttacccttaa ctgtaagaca ggctactttg
    22081 tcggaaatgg cgctggtcat gcggatgact tggactacta agcagtcgtt acaaaattct
    22141 ttcttttcaa aagtaaaaat gataaaataa aacaaatgaa acaagaggag tgtcaaatga
    22201 caaaagctaa ctttggtgtc gtaggtatgg ccgtaatggg tcgtaacctt gcccttaata
    22261 ttgaatcacg tggttacaca gttgctatct acaaccgtag taaagaaaaa acggaagatg
    22321 tgattgcttg ccatcctgaa aagaattttg taccaagcta tgacgttgaa agttttgtaa
    22381 actcaatcga aaaacctcgt cgtatcatgc tgatggttca agctggacct ggtacagatg
    22441 ctactatcca agcccttctt ccacaccttg acaagggtga tatcttgatt gacggaggaa
    22501 acactttcta caaagatacc atccgtcgta atgaagaatt ggcaaactca ggtatcaact
    22561 ttatcggtac tggagtttct ggtggtgaaa aaggtgccct tgaaggtcct tctatcatgc
    22621 ctggtggaca aaaagaggcc tacgaattgg ttgcggatgt tcttgaagaa atctcagcta
    22681 aagcaccaga agatggcaaa ccatgtgtga cttatatcgg tcctgatgga gctggtcact
    22741 atgtgaaaat ggttcacaac ggtatcgagt acggtgatat gcaattgatc gcagaaagct
    22801 atgacttgat gcaacacttg ctaggccttt ctgcagagga tatggctgaa atctttactg
    22861 agtggaacaa gggtgaatta gacagctact tgatcgaaat cacagctgat atcttgagcc
    22921 gtaaagacga tgaaggccaa gatggaccaa tcgtagacta catccttgat gctgcaggta
    22981 acaagggaac tggtaaatgg acgagccaat catctcttga ccttggtgta ccattgtcac
    23041 tgattactga gtcagtgttt gcacgctaca tttcaactta caaagaagaa cgtgtacatg
    23101 ctagcaaggt gcttccaaaa ccagctgcct tcaactttga aggagacaag gctgaattga
    23161 ttgaaaaaat ccgtcaagcc ctttacttct caaaaatcat ttcatacgca caaggatttg
    23221 ctcaattgcg tgtagcctct aaagaaaaca actggaactt gccatttgca gatatcgcat
    23281 ctatctggcg tgatggctgt atcatccgtt ctcgtttctt gcaaaagatt acagatgctt
    23341 acaaccgtga tgcagacctt gccaaccttc ttttggatga atacttcttg gatgttactg
    23401 ctaagtatca acaagcagtg cgtgatatcg tagctcttgc ggttcaagct ggtgtgccag
    23461 tgccaacttt ctcagcagct attacttact ttgatagcta ccgttcagct gaccttccag
    23521 ctaacttgat ccaagcacaa cgtgactact ttggtgctca cacttaccaa cgtaaagaca
    23581 aagaaggaac cttccactac tcttggtatg acgaaaaata agtaggtcag ccatggggaa
    23641 acggatttta ttacttgaga aagaacgaaa tctagctcat tttttaagtt tggaactcca
    23701 gaaagagcag tatcgggttg atctggtaga ggaggggcaa aaagcccttt ccatggctct
    23761 tcagacagac tatgatttga tgttattgaa cgttaatctg ggagatatga tggctcagga
    23821 ttttgcagaa aaattgagtc gaactaaacc tgcctcagtc atcatgattt tagatcattg
    23881 ggaagacttg caagaagagc tggaagttgt tcagcgtttt gcagtttcat acatctataa
    23941 gccagtcttt atcgaaaatc tggtagcgcg tatttcggcg atcttccgag gtcgggactt
    24001 cattgatcaa cactgcagtc tgatgaaagt tccaaggacc taccgcaatc ttaggataga
    24061 tgttgaacat cacacggttt atcgtggtga agagatgatt gctctgaccc gccgtgagta
    24121 tgaccttttg gcgacactta tgggaagtaa gaaagtattg actcgtgagc aattgttgga
    24181 aagtgtttgg aagtatgaaa gtgcgaccga gacaaatatc gtagatgtct atatccgcta
    24241 tctacggagc aagcttgatg ttaaaggcca aaaaagctac attaaaaccg tgcgtggtgt
    24301 tggttacacc atgcaagaat agaaaagcag ttgcagttgt gtaactgctt ttttgaggag
    24361 tttttatata ttgacatgca gtcgggtctt tgctacaatc gttttaggag gatatataga
    24421 tgaaactttt gaaaaaaatg atgcaagttc tactagcagt ctttttcttt ggtttgctag
    24481 ctacaaatac ggtatttgcg aataccacag gtggccgatt tgttgataag gataatagaa
    24541 aatattatgt aaaagatgat cataaagcaa tctattggca taaaatagac ggtaaaactt
    24601 actattttgg tgatattgga gagatggttg tcggttggca atacttagaa attcctggaa
    24661 caggttatcg tgataattta ttcgataacc aaccagttaa tgaaattggc cttcaggaga
    24721 agtggtacta ttttggacaa gatggtgctt tgctagaaca aacagataaa caagtactag
    24781 aggcaaaaac gtctgaaaat acaggaaaag tatacggtga acaatatcct ctatctgctg
    24841 aaaagagaac ttattatttt gataataatt atgctgtaaa gacaggctgg atttatgaag
    24901 acggcaattg gtattattta aataagctag gaaattttgg cgatgattct tacaatccac
    24961 taccaattgg tgaagttgct aagggttgga ctcaagattt tcatgttact attgacattg
    25021 atagaagcaa acctgctcca tggtactacc tagacccaga aactggcatt atgcgaacag
    25081 gatggcaata tctaggtaat aactggtact acctccgttc ctcaggagca atggcaacag
    25141 gttggaaata tgtacgaggc aaatggtatt acttagataa taaaaatggt gatatgaaga
    25201 ctggttggta tcaagatggt tcaacttggt actatttaga tccttctaat ggagatatga
    25261 aaataggttg gacaaaagta aatggaaaat ggtattatct caattcaaat ggagcaatgg
    25321 ttacaggtag tcaaactatc gatggtaaag tttataactt cgcttcatct ggtgagtgga
    25381 tttaatgttg gaggatatat aaaatgaagc ttttgaaaaa aactatgcaa gctggactaa
    25441 cagtaatttt ctttggtttg ctagctacga atacagtatt tgcagataac tctgaaggat
    25501 ggcagtttgt ccaagaaaac ggtagaacct attacaaaaa gggggacctc aaagaaacct
    25561 actggcgagt gattgatggt aagtactatt attttgattc tctatctgga gagatggttg
    25621 tcggctggca atatatcccg tttccatcta aaggtagtac aattggtcct tacccaaatg
    25681 gtatcagatt agaaggtttt ccaaagtcag agtggtacta ctttgataaa aatggagtgc
    25741 tacaagagtt tgttggttgg aaagaattag agattaaaac tcaagacagt gttggaagaa
    25801 agtatgggga aaaacgtgaa aattcagaag ataaagaaga gaagcgttat tacacgaact
    25861 attactttaa tcaaaatcat tctttagaga caggttggct ttatgatcag tctaactggt
    25921 attatctagc taaaacagaa attaatggag aaaactatat tggtggtgaa agacgtgcag
    25981 gttggataaa tgatgcttca gcttggtact acctagatcc agcaactggt attatgcaaa
    26041 caggttggca atatctaggt aataagtggt actacctccg ttcctcagga gcaatggcca
    26101 ctggctggta tcaggaaggt accacttggt attatttaga ccacccaaat ggcgatatga
    26161 aaacaggttg gcaaaacctt gggaacaaat ggtactatct ccgttcatca ggagctatgg
    26221 caactggttg gtatcaagat ggttcaactt ggtactacct aaatgcaggt aatggagaca
    26281 tgaagacagg ttggttccag gtcaatggca actggtacta tgcttatagc tcaggtgctt
    26341 tggcagtgaa tacgaccgta gatggctatt ctgtcaacta taatggcgaa tgggttcggt
    26401 aatgacaggg cgcttataat tatattagaa cactcgctta atcaaagaag tgactttgtt
    26461 gtacttgacc tgacgattgg ggagattaaa agcatgtgaa atctacacat gctttttcgt
    26521 tagttatgag tgttgaactt gactaaccat tgacaaaaga taagagcaat caaaataaga
    26581 tacaaaaata tcaatgctaa ctgcaccgaa acgcccgatg ctatggatag ggctaatagg
    26641 gagagcaggg acggggcgag aatgtctact gtgctcagag cagagcccac cgtccccatc
    26701 ttgtcactgg ggatatgggc aaagacagct gcttgtaggc gagggctgag aatgccgata
    26761 atcgtagaac tgatgaaact ggtcacgaaa attacgatat aggcttgaca aaggatacta
    26821 gttattagag ccaataggga aatctcacag aaaaccaaga ggtgcgtgaa acggatattt
    26881 ttaaatagat tactgctggt catattgcca aggatagctc cacaagacat gatgatggag
    26941 agcagggcga agagttgccc aatgctcagt tgtgctagtg tctgttggat gaagcggagg
    27001 gcaatcagcc gaggggacac atccaagatg gcaatcatac tggtcgtcag aaacagtagt
    27061 atgacggtat cttttaacct caggagcaca gccagcgact gtttaagatg ttgaaaatat
    27121 ttcttaaaac tcagtgctgt atgtgacatt tcaatccttt tttcaacctc atacaaggta
    27181 tgtcgaataa catacaggcc caaaaaggca atgacaaaag tcagagtgtt gataagggaa
    27241 atagtttgaa tactcataac attgataagg aatgcgccag ctagattggc gacaatgcgg
    27301 acaaccctca tcagagactg cctgaacccc atggcatcat gcaggtcgtc cttaattaca
    27361 ctgatgtaga gggcgttcat catgtaggca gacaggtagc tcaaggtgtc agagatgagg
    27421 ttgatgatga caatcataat gactgaaatt aatgaaaagg gcgacaagac gagaaatagt
    27481 gtcaaaatag cgtagagcag gattttgatt ttggcaatac agagtgcgtg tttgactcta
    27541 ttttcttgaa aatctcctag aatcccgaga aagagttgcg atagtagggg aactatctct
    27601 gaaatggaaa tcagtaaaat cgctagcgga gcgaaattgt actgagccac ataattgata
    27661 atggcgaggt agaaaatact gtcgccgaat gatgaaaaac agctgtttag cagcaactgt
    27721 ctatatatgt tgtttgtcca aaataatttc atacttttct ccttatgtct gcacatcgaa
    27781 tgggaattta ttatttaata gacaccaata taccccctgc ttcctattcc gaagtcaaac
    27841 aaatctgctt taccactatc tccttgaaac atcagtaaac cgtgatcatc tcgttcagaa
    27901 catgctaaaa ttacctgttg gattttttca tcagtaattt gttttgattg tagacagtgg
    27961 tttgtagtaa gctagttatt ccgtggcaat atcctgtcat catttttaga tgatggttaa
    28021 aaacaaattc ttgatattta ctaataatat ctttgtttcc gtcacaatcg tacatacaaa
    28081 gatataagat tattccggaa attccttcgc accaagaaag ttgtaaattt cctaaatttt
    28141 cagtattaga agtaactttt tctaataatt tttttaattc agcatggaat gtatggagat
    28201 cattatagaa catagaaggt tctaagactt tagaataggc aaataaagca tatgcaattc
    28261 cacaatatcc atgagcaaag ctatagtcta aaatgctttc tttggctgta tctctttgta
    28321 ggaaataatg ataaatttcc ccatatacta ttgtggatga aagttttaag agtattgtca
    28381 ttggtaaatt gatagtattt tattaatgat aataggacac cagattttcc caatgcaaag
    28441 tctatttcct ctagagtatc ataattctct attaatttct tagcggtgac gtttgctaat
    28501 tgtagatagt attgattttt actgatagaa aataaatgta ggagtaacca tagatagcct
    28561 gcatcaccaa atagcagtga gtattgatat tcatatgtat gtgtcgttct aattgtcact
    28621 gccttcttga tgatagagag tattttagaa tccagttctg gggggtacaa tttatttaga
    28681 ggaaacagta gtccagctat tccgtgttgg aatgataaat tacttacgaa atttctaaat
    28741 tctgttgaag aagtgatcct tccttcagaa tttacagttt tatctagtaa aaattgtaga
    28801 acactattac attctgtttt gtaatcatat ttatgttcct ctattttttt aattttgact
    28861 aaattatttg tttgacttaa atttagtaga cattgtaacc aaaatagttg ctcatctgtg
    28921 agctgacctt gagtatgtga tagttctagt aattgaatag gatcctttag gtagattcaa
    28981 tcaatctata acacaacaac ataataacac ttttaggata acttatcaaa
//
LOCUS       DAVMAH010000030        27487 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVMAH010000030 DAVMAH010000000
VERSION     DAVMAH010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27487
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.030"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            210..2390
                     /locus_tag="VYO94_001213"
     CDS             210..2390
                     /locus_tag="VYO94_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1759851.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            2442..3257
                     /locus_tag="VYO94_001214"
     CDS             2442..3257
                     /locus_tag="VYO94_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1759852.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYNRYHEGV
                     AILSKTPIETREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            3397..4740
                     /locus_tag="VYO94_001215"
     CDS             3397..4740
                     /locus_tag="VYO94_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1759853.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            4955..6145
                     /locus_tag="VYO94_001216"
     CDS             4955..6145
                     /locus_tag="VYO94_001216"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV1759854.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            6698..7633
                     /locus_tag="VYO94_001217"
     CDS             6698..7633
                     /locus_tag="VYO94_001217"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV1759855.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVVCMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            7667..8704
                     /locus_tag="VYO94_001218"
     CDS             7667..8704
                     /locus_tag="VYO94_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1759856.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            8877..9482
                     /locus_tag="VYO94_001219"
     CDS             8877..9482
                     /locus_tag="VYO94_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV1759857.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            9639..10169
                     /locus_tag="VYO94_001220"
     CDS             9639..10169
                     /locus_tag="VYO94_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV1759858.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            10190..11275
                     /gene="rlmN"
                     /locus_tag="VYO94_001221"
     CDS             10190..11275
                     /gene="rlmN"
                     /locus_tag="VYO94_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV1759859.1"
                     /translation="MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFAERGQDERVNHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRNFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            11275..11757
                     /locus_tag="VYO94_001222"
     CDS             11275..11757
                     /locus_tag="VYO94_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1759860.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            11759..13300
                     /locus_tag="VYO94_001223"
     CDS             11759..13300
                     /locus_tag="VYO94_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1759861.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(13356..14159)
                     /locus_tag="VYO94_001224"
     CDS             complement(13356..14159)
                     /locus_tag="VYO94_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV1759862.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(14242..14454)
                     /locus_tag="VYO94_001225"
     CDS             complement(14242..14454)
                     /locus_tag="VYO94_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759863.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            complement(14933..15142)
                     /locus_tag="VYO94_001226"
     CDS             complement(14933..15142)
                     /locus_tag="VYO94_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759864.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            15312..15584
                     /gene="rpsP"
                     /locus_tag="VYO94_001227"
     CDS             15312..15584
                     /gene="rpsP"
                     /locus_tag="VYO94_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV1759865.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            15604..15843
                     /locus_tag="VYO94_001228"
     CDS             15604..15843
                     /locus_tag="VYO94_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV1759866.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            16420..17208
                     /locus_tag="VYO94_001229"
     CDS             16420..17208
                     /locus_tag="VYO94_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1759867.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELLE"
     gene            17239..17757
                     /gene="rimM"
                     /locus_tag="VYO94_001230"
     CDS             17239..17757
                     /gene="rimM"
                     /locus_tag="VYO94_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV1759868.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            17747..18466
                     /gene="trmD"
                     /locus_tag="VYO94_001231"
     CDS             17747..18466
                     /gene="trmD"
                     /locus_tag="VYO94_001231"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV1759869.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            18478..18816
                     /locus_tag="VYO94_001232"
     CDS             18478..18816
                     /locus_tag="VYO94_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759870.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(18847..19167)
                     /locus_tag="VYO94_001233"
     CDS             complement(18847..19167)
                     /locus_tag="VYO94_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759871.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            19265..19480
                     /locus_tag="VYO94_001234"
     CDS             19265..19480
                     /locus_tag="VYO94_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV1759872.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(19731..20267)
                     /locus_tag="VYO94_001235"
     CDS             complement(19731..20267)
                     /locus_tag="VYO94_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV1759873.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQVLVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(20464..21810)
                     /gene="gor"
                     /locus_tag="VYO94_001236"
     CDS             complement(20464..21810)
                     /gene="gor"
                     /locus_tag="VYO94_001236"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV1759874.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            22075..23274
                     /locus_tag="VYO94_001237"
     CDS             22075..23274
                     /locus_tag="VYO94_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV1759875.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KTDEATN"
     gene            23258..23959
                     /locus_tag="VYO94_001238"
     CDS             23258..23959
                     /locus_tag="VYO94_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759876.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            23961..25220
                     /locus_tag="VYO94_001239"
     CDS             23961..25220
                     /locus_tag="VYO94_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1759877.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESL
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            25344..27341
                     /gene="metG"
                     /locus_tag="VYO94_001240"
     CDS             25344..27341
                     /gene="metG"
                     /locus_tag="VYO94_001240"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV1759878.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLDKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
BASE COUNT         8398 a         5039 c         5990 g         8060 t
ORIGIN      
        1 aagaaaagag cttccaaaga agttccctag agaagacttc ttgatggcta atttgaactt
       61 gaaatttgac tcactagaaa ttttttagaa aaaagtgtaa tttttttata aaagccttta
      121 caaaaaaaat taaagtggta taattaaatt atagaaggtg caaacgtttt cgtaaaacgt
      181 ttgcctaaat aaaaataaag gagatttgaa tgatgaaaga tacattcaaa aatgtcttgt
      241 ctttcgaatt ttggcaaaaa ttcggtaagg ctttgatggt agttatcgcg gttatgccgg
      301 ctgctggttt gatgatttca atcggtaagt ctatcgtgat gattaaccca acctttacac
      361 cacttgtcat cacaggtgga attcttgagc aaatcggttg gggggttatc ggtaaccttc
      421 acattttgtt tgccctagcc attggaggaa gctgggctaa agaacgtgct ggtggtgctt
      481 tcgccgctgg tcttgccttc atcttgatta accgtatcac tggtacaatt tttggtgtat
      541 caggcgatat gttgaaaaat ccagatgcta tggtaactac tttctttggt ggttcaatca
      601 aagttgctga ttactttatc agtgttcttg aagctccagc cttgaacatg ggggtattcg
      661 tagggattat ctcaggtttt gtaggggcaa ctgcttacaa caaatactac aacttccgta
      721 aacttcctga tgcactttca ttcttcaacg ggaaacgttt cgtaccattt gtagttattc
      781 ttcgttcagc aatcgctgca attctacttg ctgctttctg gccagtagtt caaacaggta
      841 tcaataactt cggtatctgg attgccaact cacaagaaac tgctccaatt cttgcaccat
      901 tcttgtatgg tactttggaa cgtttgctct tgccatttgg tcttcaccac atgttgacta
      961 tcccaatgaa ctacacagct cttggtggta cttatgacat tttaactggt gcagctaaag
     1021 gtactcaagt attcggtcaa gacccactat ggcttgcatg ggtaacagac cttgtaaacc
     1081 ttaaaggtac tgatgctagt caatatcaac acttgttaga tacagtacat ccagctcgtt
     1141 tcaaagttgg acaaatgatc ggttcattcg gtatcttgat gggtgtgatt gttgctatct
     1201 accgtaatgt tgatgctgac aagaaacata aatacaaagg tatgatgatt gcaacagctc
     1261 ttgcaacatt cttgacaggg gttactgaac caatcgaata catgttcatg ttcatcgcaa
     1321 cacctatgta tcttgtttac tcacttgttc aaggtgctgc cttcgctatg gctgacgtcg
     1381 taaacctacg tatgcactca ttcggttcaa tcgagttctt gactcgtaca cctattgcaa
     1441 tcagtgctgg tattggtatg gatatcgtta acttcgtttg ggtaactgtt ctctttgctg
     1501 taatcatgta ctttatcgca aacttcatga ttcaaaaatt caactacgca actccagggc
     1561 gcaacggaaa ctacgaaact gctgaaggtt cagaagaaac cagcagcgaa gtgaaagttg
     1621 cagcaggctc tcaagctgta aacattatca accttcttgg tggacgtgta aacatcgttg
     1681 atgttgatgc atgtatgact cgtcttcgtg taactgttaa agatgcagat aaagtaggaa
     1741 atgcagagca atggaaagca gaaggagcta tgggtcttgt gatgaaagga caaggggttc
     1801 aagctatcta cggtccaaaa gctgacattt tgaaatctga tatccaagat atccttgatt
     1861 caggtgaaat cattcctgaa actcttccaa gccaaatgac tgaagcacaa caaaacactg
     1921 ttcacttcaa agatcttact gaggaagttt actcagtagc agacggtcaa gttgttggtt
     1981 tggaacaagt aaaggatcca gtatttgctc aaaaaatgat gggtgatgga tttgcagtag
     2041 aacctgcaaa tggaaacatt gtatctccag tttcaggtac tgtgtcaagc atcttcccaa
     2101 caaaacatgc ttttggtatt gtgacggaag caggtcttga agtattggtt cacattggtt
     2161 tggacacagt aagtcttgaa ggtaaaccat ttacagttca tgttgctgaa ggacaaaaag
     2221 ttgcagcagg agatctcctt gtcacagctg acttggatgc tatccgtgca gcaggacgtg
     2281 aaacttcaac agtagttgtc ttcacaaatg gtgatgcaat taaatcagtt aaattagaaa
     2341 aaacaggttc tcttgcagct aaaacagcag ttgctaaagt agaattgtaa tatacttgag
     2401 gttggaagct gtattccaac ctcttatttt gggagaaaag aatgaaattt ttaacactca
     2461 atactcacag ttggatggag aaagaagcag aggaaaaatt ccagattttg cttgaagata
     2521 ttcttgaaaa ggactatgat ttgatttgtt ttcaagaaat caatcaggag atgacctcgt
     2581 cagaggtgga ggttaatgac ctttatcaag ctttgccagc agctgagcct attcaccaag
     2641 accattatgt tagactcttg gttgaaaagt tgtctgagca agggaaaaat tactactgga
     2701 cctgggccta taaccatatc ggctataacc gctaccacga aggtgtggct atcttgtcta
     2761 aaacacctat tgaaaccaga gaaattttgg tttcagatgt ggatgatcca acagactatc
     2821 atactcgccg tgttgcccta gctgaaactg tagtcgatgg caaggagcta gcagttgcca
     2881 gtgttcatct ctcttggtgg gataaaggtt tccaagaaga atgggcacga tttgaggctg
     2941 tcttgaaaaa attgaacaag ccacttttac tagctggaga tttcaacaat ccggctggac
     3001 aggaaggtta ccaagctatt ttagctagtc cattaggctt acaagacgca tttgaagttg
     3061 ctcaagagaa aagtggtagc tatactgttc cgcctgaaat tgatggctgg aaagggaaca
     3121 ctgaacccct tcgaatcgat tatgtcttta ctaccaaaga gttagcggtg gaaaatttac
     3181 atgtcgtatt tgatggtaac aagagtccac aagtgagtga tcactatggc ttgaatgcta
     3241 tgttaaactg gaaataataa ctgaaaagag gttggaacta taaaattcca gccttttctt
     3301 actagagaag ctactggaaa tagcctaaat aagtgagact actgtaatgg aataaaatat
     3361 ggtataattg ataagataga tagaatcgag gatgttatgt catttacgaa atttcaattt
     3421 aaaaactata ttagagaagc cttggaggag ttaaaattta caactccaac agaggtgcaa
     3481 gacaagttga ttcctattgt tttggcaggt cgtgacctag taggagaatc aaaaacaggt
     3541 tcaggtaaga ctcatacttt cttgttaccg attttccagc aattagatga agctagcgat
     3601 agtgtacaag cagtgattac tgcaccgagt cgtgagttgg ctactcaaat ttaccaagta
     3661 gcgcgtcaga tttcagctca ctcagatgtc gaagttcgtg tggttaatta tgtgggtggt
     3721 acggataagg ctcgccagat tgagaaattg gcaagcaatc agcctcatat tgttattgga
     3781 acaccaggcc gtatctacga cttggttaaa tctggtgatt tagctattca taaagccaag
     3841 acatttgttg ttgatgaagc ggatatgacc ttggatatgg gattcttgga aactgttgat
     3901 aagattgctg gcagtcttcc aaaagacttg caattcatgg tcttctcagc gactatccca
     3961 caaaaactgc aaccattctt gaaaaaatac ttatccaatc ctgttatgga gaaaattaag
     4021 accaaaacgg ttatttctga caccattgat aattggttga tttcgaccaa gggacatgat
     4081 aagaatgctc aaatttacca gttgactcag ttgatgcagc cgtatttggc aatgattttt
     4141 gttaacacta aaacgcgtgc tgatgaattg cattcatatc tgactgctca aggcttgaag
     4201 gttgcaaaaa tccatggcga tattgcccct cgtgaacgca agcgaatcat gaatcaggtg
     4261 caaaatctgg attttgagta tattgtcgca acagatttgg cagcacgtgg gattgacatt
     4321 gaaggtgtca gccatgtcat caatgatgcc attccgcaag acttatcttt ttttgttcac
     4381 cgtgttggtc gtactggacg aaatggccta ccaggtacag ctattaccct ttatcagcca
     4441 agtgatgact cggatatccg tgagttggag aaattgggaa tcaagtttag tcctaagatg
     4501 gtcaaagacg gggaatttca agatacctat gaccgtgatc gtcgtgccaa ccgtgagaaa
     4561 aaacaagata aacttgatat cgaaatgatt ggtttggtta aaaagaaaaa gaaaaaagtc
     4621 aaaccgggtt ataagaagaa aattcaatgg gcggttgatg aaaagcgccg taaaaccaag
     4681 cgtgctgaaa atcgcgctcg cggtcgtgca gagcgtaaag ctaaacgtca aacattttaa
     4741 tagaaattgt tggagtactg agctccaact ttttgcttta tgagaacgaa ctatctaaac
     4801 cgaaacacta cattaaagac tgcaaattga gattaaaaat ggtataatga taaagttata
     4861 tagtcccgat aagatggtag gtatttatta cgaagagttt tcctatcagt actttgtaac
     4921 tctataacaa tattttttaa ggggggacat ttttatgtca gaacgtaaat tattcacgtc
     4981 tgaatctgta tctgaggggc atccggataa gattgcagac caaatttcag atgcgatttt
     5041 ggatgctatt ttagcaaagg atccagaggc gcacgttgct gctgaaacag ctgtatatac
     5101 tggttctgtc cacgtttttg gtgaaatttc tacaaatgcc tatgtggata ttaaccgtgt
     5161 ggttcgtgat accattgcag agattggtta taccaataca gaatatggat tttctgctga
     5221 gacggtggga gtacacccat ctttggtgga acaatctcct gacatcgctc aaggtgttaa
     5281 cgaagccttg gaggttcgtg gaaatgctga tcaagatcca ctggacttga ttggagcagg
     5341 tgaccaaggg ctcatgtttg gatttgcagt agatgaaaca gaagagctca tgccattgcc
     5401 aattgcactc agtcataaat tggttcgtcg tctggcagaa cttcgtaagt ctggagaaat
     5461 tagctatctc cgtccagatg caaaatcaca agttacagtt gagtacgatg aaaatgaccg
     5521 tccggtacgt gtagatacag tcgttatttc tactcagcat gatccagagg ccactaatga
     5581 acaaatccat caagatgtga ttgacaaggt catcaaagaa gttattccat cttcttatct
     5641 tgatgataag acaaaattct ttatcaatcc gacaggtcgt tttgtaatcg gtggtcctca
     5701 aggggactca ggtttgactg gtcgtaagat tattgtagat acttatggtg gctactctcg
     5761 tcatggtggt ggtgccttct ctggtaaaga tgcgactaag gtggatcgtt cagcctctta
     5821 tgcggctcgc tatattgcca agaatatcgt tgcagcaggc cttgctaaga aggcagaagt
     5881 gcagttggcc tatgctatcg gtgttgcgca acctgtttct gttcgtatcg atactttcgg
     5941 tacaggaaca gtagctgaaa gtcaacttga aaaagcggct cgtcaaatct ttgaccttcg
     6001 ccctgcaggg attatccaaa tgctggacct caagcgtcca atttaccgtc aaacatcggc
     6061 ttacggtcac atgggacgta cagatattga tcttccatgg gaacgtttgg ataaggtaga
     6121 tgctttgaaa gaagcagtaa aataagattt taagagggga acgtcctctc ttttttatag
     6181 tttttaacta tactgggata ctgttctgaa aatccatttt gcgaaagtag agatttacat
     6241 gtatagtaga ttgaaactag aatagtacac ctcaacttct aaaacattgt taaaaatcga
     6301 tttgactgtc ctgatcgatt tctcctgttc ttgtttcatt ttactatatt tctttaaaaa
     6361 tgataaaggt tgagatttct cctcgtaata gataatcttg gggatatttc aatccaaagt
     6421 tttattcgtt atcacttgac tattgcaagg ttttctagag caacagagtc atggaataga
     6481 ctcatggttg agatttctcc ttgttgcttg gacttcattc aaaagtctgt tacccaagcc
     6541 ttgttcaaac ttctaataca ctagctgttt ccatagcatg acttctgtac tagactttct
     6601 tttccgaata aatagataga accacagaat ctagtaaacc tagaattaaa attatggtat
     6661 aatattagca ataaaagaaa tctggaggat tagaatcatg gtatcaacga aaacacaaat
     6721 tgctggtttt gagtttgaca attgcttgat gaatgcagca ggtgtggttt gtatgacgat
     6781 agaggagtta gaagaggtca aaaactcagc ggcaggaacc tttgttacta agacagcgac
     6841 cttggacttc cgtcagggga atcctgagcc acgctaccaa gatgttccac ttggttccat
     6901 caactctatg ggcttgccaa ataatggctt agactattat ttggattatc ttttggattt
     6961 gcaggaaaaa gagtcgaacc gaactttctt cttatctctg gtcggcatgt ctccagagga
     7021 aacccatact attttgaaaa aagtccaaga gagtgatttt cgtggtctga ctgagctaaa
     7081 tctttcctgt ccaaatgttc caggtaaacc tcagattgcc tatgattttg agacaacaga
     7141 ccggattttg gcagaagtgt ttgcttactt caccaaacct cttggaatta aattgccacc
     7201 ttattttgat attgttcact ttgaccaagc ggcagctatt ttcaacaaat atccgctcaa
     7261 gtttgtcaac tgcgttaact ctatcggaaa cggcctctat atagaagacg aatctgtcgt
     7321 tattcggcct aagaatggtt ttggtggaat tggtggagaa tacatcaaac cgactgctct
     7381 agccaatgtt cacgcctttt atcaacgttt aaatcctcaa atccaaatta tcggaacagg
     7441 tggcgttctg actggtcgag atgcctttga acacatcctc tgtggagcaa gtatggtgca
     7501 ggtgggaacg acccttcaca aagaaggcgt cagtgctttt gaccgcatta ccaatgaact
     7561 gaaagcaatc atggtggaaa aaggctacga gagcttagaa gatttccgtg ggaaattgcg
     7621 ctatattgac taaattaaat cgaaaaatca gaagaaagaa gggacgatgc tagccattga
     7681 agaaagtcag aagttgactt tatcaaattt accgagcctg agcctattta cagggacaga
     7741 tcagggtcag tttgaagtga tgaagagtca aatgttgaaa cagattgggt atgattctgc
     7801 tgacctcaac tttgcctact ttgatatgaa agaagtagtt tacaaggatg tggaactgga
     7861 gttggtcagc cttcctttct ttgcggatga gaaaatcgtg atattagatt attttatgga
     7921 tatcacgact gctaagaaac gctttttgac agatgatgag cttaagtcat ttgaggaata
     7981 ccttgacaat ccttctccaa caaccaagtt gataatcttt gcagaaggaa agctggatag
     8041 caaaagacgg ttagtcaaat tacttaagcg tgatgccaag gtcttcgatg cagtagaagt
     8101 aaaagaacaa gaattgcgcc aatatttcca aaagtggagt cagaaacaag gtctgcagtt
     8161 taccaatcat tcttttgaaa atctcctcat caagtcgggg tttcaattta gcgaaatcca
     8221 gaaaaatctt ctctttttac agtcctataa ggcggattct gttatcgagg aagaggatat
     8281 tgttaacgca attcccaaga ccttgcagga caatattttt gatttaactc agtttattct
     8341 gactaaaaag atggatcagg cgcgcgattt ggtgagagac ttgaccttgc aaggggaaga
     8401 tgaaatcaaa ctgattgcag tcatgctggg acaatttcgg acttttactc aggtgaagat
     8461 tttggcggag tctggccaaa cagaatcgca gattgcaagt agtttaggta gttatctggg
     8521 acgtaaccca aatccttatc aaatcaagtt tgcattaaga gattcgagag gactttcttt
     8581 gagctttctg aagcaagcta tttcctattt gattgagaca gactatcaga ttaagacagg
     8641 tctttatgaa aaaggtttcc tttttgaaaa ggcactctta cagattgcta gtcaggtcaa
     8701 ttgacatttg ttgaaactac aacccgcgtc aggattatct tgtcgtgggt ttcttgctga
     8761 tttgcttatt ttattagaaa gtatgtcagt gatttcctta tctataagca aaaaacttga
     8821 aaaaagtgaa tgtttgcgtt atcattttca tatagaaaga aaaagaggta ttacagatgg
     8881 ctattatctt accagaactt ccatatgcat acgacgcttt ggaaccatac atcgatgcgg
     8941 aaacaatgca tttgcaccat gacaaacacc atcaaactta tgtcaacaat gccaatgcag
     9001 ctttagaaaa acaccctgaa atcggtgaag accttgaagc cttgcttgct gatgtagaat
     9061 ctatcccagc tgatatccgt caagcactta tcaacaatgg tggcggacac ttgaaccacg
     9121 ctcttttctg ggaattgatg actcccgaga aaacagctcc ttcagcagaa ctggcagcag
     9181 caatcgatgc aacatttggt tcatttgaag aattccaagc agccttcact gcagcagcaa
     9241 caactcgttt tggttcaggt tgggcatggt tggttgtcaa caaagaaggg aaacttgaag
     9301 tgacttcaac agcaaaccaa gacacaccaa tctcagaagg taaaaaacca atcttgggct
     9361 tggacgtttg ggaacatgct tactacgtga aataccgcaa cgtgcgtcct gactacatca
     9421 aagctttctt ttcagtaatc aactggaata aagtagatga attgtacgca gctgctaaat
     9481 aatgatagtt ggagggaaga attgttcttc tcttttttag gttataagat tctggtctga
     9541 caaaatcgtt agactttttt catttttatg agaaacgtgc taactgctag aaattatggt
     9601 agaataaagt attaagtaat cgtggaaaaa ggatatctat gcgaaaagaa attgcacctg
     9661 aattatacaa ctataacaag tttcctggtc cggagttcca tttacacggg gataaggtcg
     9721 aaacggaagg gatagctttt tccttggttg aaaatatcaa ggatgccttt gatgtgacga
     9781 cttttaatca gcgtttttca gaagtcttaa ccaagtttga ttatatcgtg ggggactgga
     9841 gcaacgaaca gcttcgccta cgaggttttt acaaggatga ccgaacagaa gaaaaacttg
     9901 aaaaaatcag tcgtttacaa gactaccttt tagagtattg tagttatggt tgtgcctatt
     9961 ttgtcttaga aaatgaagcc cctaagcgag catcatttga caagaaaatg cgtaagacgg
    10021 aagaagaaac accttctaga aaaggaaaga aaccgactca aactaaacga aagtcgaatg
    10081 cagataagaa gaatagacgt cgtcagaaag accagcattc tcagaaagag gacaagggac
    10141 aacgtcattt tgtcattcgt cagaagtgag tagagaataa ggagaagaaa tgaaaccttc
    10201 aattcatagt ttgacacatc aaaccatgca ggaatgggta ttggagcagg gagaaaagaa
    10261 attccgtgca gatcaaatct gggaatggct ctaccgtaaa cgtgtgcagt catttgaaga
    10321 aatgaccaac ctttccaagg atttgattgc taagctcaat gaccagtttg tggtcaatcc
    10381 cttgaaacaa ggtattgtgc aagagtctgc tgatggtaca gtcaaatatc tctttgaatt
    10441 gcctgacggt atgttaattg agactgtact catgcgtcaa cactatggtt tatctgtctg
    10501 tgtgaccact caggtcggct gtaatatcgg ttgtaccttc tgtgcctctg gtttgattaa
    10561 gaagcaacgt gacctcaata acggtgaaat cgtagcgcaa atcatgctgg ttcagaaata
    10621 ctttgctgag cgtggtcagg atgaacgcgt caaccatatc gttgtcatgg gaatcggtga
    10681 gccctttgat aattacaaca atgtcttgaa tttctttcgt actatcaatg atgataaagg
    10741 aatggctatc ggtgctcgtc acatcacggt ttcaacctca ggtttggctc ataaaattcg
    10801 taactttgct gatgaagggg ttcaggtcaa tcttgccgtg tctcttcacg cacctaacaa
    10861 tgaacttcgt tcaagtatca tgaagattaa ccgtgccttt ccgattgaaa aactctttgc
    10921 tgctattgaa tactacattg agacaacaaa ccgtcgtgta acctttgaat atatcatgct
    10981 taatgaagtc aacgacggtg tagaacaagc cttggaattg gctgaattgc tcaagaacat
    11041 caagaaattg tcttatgtaa acttgattcc ttataaccca gttagtgagc atgaccaata
    11101 tagccgtagt cccaaagagc gcgtgttggc tttctatgat acgcttaaga aaaaaggggt
    11161 caactgtgtg gttcgtcaag agcatggtac agatattgac gcagcttgtg gacaattgcg
    11221 ctctaacaca atgaaacgtg accgccagaa ggcagtcgca gcggtaaatc cttaatgatg
    11281 aagaagactt ataatcatat tttggtctgg ggagtcattt tctatagcat ttgcattgtc
    11341 tgtttttgct ttactcctca agaacaatct accgtgggag tgggaactcc aggtattcag
    11401 catcttggac gcctggtttt tcttttgact cctttcaatt ctctctggaa actgggcgaa
    11461 gtgagtgaca ttggacaatt atgttggatt tttttacaaa atgtcctcaa tgtcttcttg
    11521 ttttttcctc tgattttcca actcctttat ctatttccaa atttgcggaa aacaaaaaag
    11581 gtccttcttt ttagttttct tgtgagtctt ggaatcgagt gtacgcaatt aatcttggac
    11641 tttttctttg atttcaatcg cgtctttgag attgatgatt tgtggaccaa tactttgggt
    11701 ggctatctgg cttggctcct ttataaacga ttacataaaa acaagataag gaattaaaat
    11761 gagtatttta gaagttaaaa atctgagtca cggttttggt gaccgtgcaa tttttgaaga
    11821 tgtgtccttc cgtctcctca agggagaaca tatcggcctg gtcggtgcca atggtgaagg
    11881 aaaatcaacc tttatgagta tcgtgactgg taaaatgctg ccagatgaag gaaaggttga
    11941 gtggtccaaa tatgtgacgg ctggttactt ggatcagcac tctgtccttg ctgaaagaca
    12001 gtcggtgcgt gatgttctcc gtacggcttt tgatgagctt ttcaaagctg aagctcgtat
    12061 caatgacctc tatatgaaaa tggctgaaga cggcgcggat gttgatgctc tcatggaaga
    12121 agtaggagaa cttcaagacc gtctggagag tcgtgatttc tataccttgg atgctaagat
    12181 tgacgaagta gcgcgtgctc ttggtgttat ggactttggc atggatacgg atgtaacttc
    12241 tttgtcaggt gggcaaagaa ccaaggtgct tttggcaaaa cttctccttg aaaagcctga
    12301 tatcttgctg ttggacgagc cgaccaacta cttggatgct gagcatattg attggctcaa
    12361 gcgctatctc caaaactatg agaatgcctt tgttctcatt tcgcacgata ttccattcct
    12421 caatgacgtt attaatattg tctatcatgt ggaaaatcaa cagctgacgc gttactctgg
    12481 tgactactac cagttccaag aagtttatgc tatgaagaaa tctcagctag aggcagccta
    12541 cgaacgccag cagaaagaga ttgcagacct caaggacttt gtggctcgta ataaagcccg
    12601 tgttgcaact cgtaatatgg ctatgtctcg tcaaaagaaa ttggataaga tggatattat
    12661 cgaactccaa agtgagaaac caaaaccatc ctttgatttc aaaccagctc gtacaccagg
    12721 gcgctttatc ttccaagcca agaacttgca aattggttac gaccgtcctc ttactaagcc
    12781 tttaaatctt accttcgaac gcaatcaaaa ggttgcgatt attggtgcta atggtattgg
    12841 aaaaacaact ctcttgaaga gtctcttagg cattatctcg ccaatcgctg gggaagtgga
    12901 gcgtggagat tatttagaac ttggttattt tgagcaggaa gtagaaggtg gtaatcgcca
    12961 aactcctctt gaagctgtct ggaatgcctt tcctgccctt aatcaagcag aagtccgtgc
    13021 agcccttgcc cgttgtggtt tgacaaccaa acatattgaa agccagattc aagtattatc
    13081 agggggagag caagccaagg ttcgtttctg tctcttgatg aatcgtgaaa acaacgtttt
    13141 agtgctggac gagccgacca accatttgga tgtggatgca aaggatgagc tcaaacgcgc
    13201 tctcaaagaa tataggggat ctatccttat ggtctgccac gagccagact tttatgaagg
    13261 ctggatagac caaatatggg attttaataa tttaacttaa gaatgagagt aaaagaaata
    13321 cagtaccgaa tgtggatact gtattttttt ggtttttaag atttaaaatc gtagtctttc
    13381 accacttcga tgctgtcgat tgtgatagca gtagttggct tgtctttttc atctttttcg
    13441 gccttagcaa tcttatccac aacatccata ccgtcaatca cttgaccaaa gactgggtgt
    13501 ttgccatcta gactagggtt tccaccttct ttgtaggctt cgataatttt ctgtggatac
    13561 ttgcttgtag ggagtttaga agaggtatct gtagagtttt ggttgatgaa gaactggctg
    13621 ccattggtgt ttggttgacc agtattagcc atagcaagag caccgcggat gttatacaaa
    13681 taaggagtaa tctcgttctt gaaaccagtt cctttgtctt tagtcttatc cttgtcatgc
    13741 cagatggact gaccacctgt accgtcccct tttggatctc cagtttggac cataaagcca
    13801 tcgatgacac ggtggaaggt aataccgtta tagtagcctt ctttggcgtg agtgaggaaa
    13861 ttttcaaccg ctagaggagc gagtttaggg aagagtttaa tgcgaatatc accttggctt
    13921 gtgtggagaa tcacttcggc ttcatcttca gcaacttcct tagatagttg tgggaaattg
    13981 gcgttttcgt ttgttaaagc atcgtttaac tccttggcag attgggcagc tactttggaa
    14041 ctttcttcag cagcaagact ggaatcaaca taatcatcac cacgcagact gcgttggacg
    14101 ctgctacacc cagctagggc tacagtagac agtaaaagaa gggttgctag ttttttcatt
    14161 ctgatcctct caaaaattca tttataccat tgtaccctaa aaggaagtgg atttcaaata
    14221 ttagtagttt acagaactgg cttagataat agttgggatt tcatcatcat cttgaaaatc
    14281 ttcaacttct tccccagtaa atggtttctg aaaagaactt agtataaaac gggcaattgg
    14341 ttcaacaatt aggaaattta gaggaagagc tgcaataaag tttacgaacc aggcgcttag
    14401 ataggtattg ggtgtgatag caatgccatt gtaaaaaagt ccatagaagg acatgaaagt
    14461 gaccagctaa ttcttcttct gaaaaatgct catgaagggc ttgatccagg tcgcaagatt
    14521 tcattttaga aagtccagta actcccttct tcttcaggat attctttttc atggtattat
    14581 ttagatggtc aagtgagtca aaagaagttt cgacaagagc ataccctttt tctaccagag
    14641 tttttagatg tttaggggca tcaataccat aagtgtactc aaagtatttt ggaaaccaga
    14701 tcttaagaaa gctcgtaaag ctagccagtt ctctaaacgc taagaactag ctacaacaca
    14761 gcatttacaa cacttcatgg ttcacaccat ggggtgtttt ttaatgattt taagcaaaat
    14821 tcacacttaa ttgaaagtta tttaaattag atgaaaattt attttttgaa aaagtgggaa
    14881 aacattgatt ctaagcgaat tttgaatcat attcgaatgg gagtttttaa aatcatgttt
    14941 cagtggtaaa agtaccaaac tggattctcc atagtaaaat gatatctcct gctagtgaat
    15001 catctactaa taagtccata tttcgcttgg gaacgggctt gggacttaga agccaagtat
    15061 ccaactctcg ttcaggcgat atgaagggtt tgacttggtg ttctttataa aatttttcta
    15121 aaatagtatt cacggatagc atctttcaaa catttatttc ctattctaac aaatttctaa
    15181 atactttaag aaatttatag tctgtcaagt ttttttcttg acacatgcca gaaatctgct
    15241 ataatagaac atgtgctaaa tagctcagct atttcaccga aataaaaaat taaagaaatg
    15301 agactttaaa aatggcagtt aaaatccgtt tgactcgtat gggttctaag aaaaaacctt
    15361 tctaccgtat caacgtagca gattcacgtt caccacgtga cggacgtttc atcgaaacag
    15421 ttggaactta caacccactt gttgctgaaa accaagtaac tttgaaagaa gaccgcgttc
    15481 ttgcatggtt ggctaatgga gctcaacctt cagacacagt acgtaacatc ctttcaaaag
    15541 aaggcgtatt gaaaaaattc cacgattcta aattctcaaa ataagtttaa agtaggttga
    15601 cagatggata cgattgaaaa tctcattatt gcgattgtga aacccttaat ttcacaacca
    15661 gatgccttaa ctatcaagat tgaggataca ccagaatttt tggaatatca tttgaatctt
    15721 gatcaaagcg atgtgggtcg tgtaatcggt cgtaagggtc gcactatttc tgcgataaga
    15781 acgattgtct actctgtccc aactgaatac aaaaaagtaa gaatcgttat tgacgaaaaa
    15841 taagaagggc gggacggatg tctcgctttt ttgtgtggaa tagaagatat agtaaaatga
    15901 aataataaca ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaag
    15961 taaaggtgta ctattctagt ttcaatatac tataaaagat tgaacgttta ggcaattcca
    16021 agactactta atcgaacatt aacagcagtc tcggactgat gaaggtcttt ttatgaagtt
    16081 agtggaggaa gtcggagaag tagccgaggt tttgaatagg cgctctggtc gaaaagaagg
    16141 gataggattc gaacgaggaa cttgccagag aactggctga tatcatttac tacaccgtcg
    16201 caatcgtagc tattaatcat attgacctta ccaagactgt ctttgagaaa gacaaaaccg
    16261 cagccgttaa ttaccaacat aaacataatt tggaaggatt attgaaggga aagtagagat
    16321 attgtcccct tcctccaact tgagaaaatc cttggaacgt gataaaataa aggataagga
    16381 tttttaataa ttcattatat agaatcagtg gatttcttta tgaagaggtt tgaagtatct
    16441 acagaaattg gtagcctctc tgttacttat caaaagcaaa agaaagtgct agtttgtcta
    16501 aacggagcag gtttgctacc aagttatgaa aatttttcac ttatacttga aaaacctcct
    16561 cctacaattg gttatttgac aattgatttt ccgaacacag gtaggagtcc gattcatgac
    16621 caagctggaa aaaatctaga taatcttgca gatgcggttt atgaagtact tgaagaatta
    16681 ggaatttctg aatatatact ttgtgcacat agttggagtg gaattttagc ttgcaaatta
    16741 ctcgagaaac caattaagcg tcagacttta gtagcaattg aaccgacaac taaaaaagtc
    16801 atgtttgctg atttttcaga aaatccttat ccagaaatgg aagagcagat gaggctgatt
    16861 gacgagtgtg gtcctgaact ttattttaag aacttaactc aagcaacatt tagtcctgaa
    16921 acgaataaaa aaatctggga attaatgcaa gaaaaaggct tagagttgga aaatcaagat
    16981 ccagaatttc agatatctgg agagattact gaggaagatt ttgaggatgt atctatagaa
    17041 gctcatattc ctgtatttgt tttttgtcag ccttatagag aaaaagagta cagagaatca
    17101 gaatattgga cttccaatac taaactcatt ttaggaggga atcaccatta tttacaatgg
    17161 tcagaatcgg aaaaaattgc ggctattatt cgagaattat tagaataaga tggaaaaaag
    17221 gagattacag gagacaagat gaactacttt aatgttggga aaatcgttaa tacgcaggga
    17281 ttacagggtg agatgcgagt cttgtctgtg acggattttg cagaagaacg gtttaaaaaa
    17341 ggagctgagc tggctttgtt tgatgaaaaa gatcagtttg tccaaacagt gaccatcgct
    17401 agccaccgta aacagaagaa ctttgacatt attaaattca aagatatgta ccatatcaat
    17461 actatcgaaa agtacaaggg atacagtctc aaggtcgctg aggaagattt gaatgaccta
    17521 gacgatggtg aattttacta tcacgagatt atcggtttgg aagtctatga gggtgatagc
    17581 ttggttggaa ccatcaagga aatcctgcaa ccaggtgcta atgatgtctg ggtggtcaaa
    17641 cgaaaaggca aacgtgattt gcttttacct tatatcccac cagtggttct caatgttgat
    17701 attccaaata aacgggtcga tgtggaaatc ttagaagggt tagacgatga agattgatat
    17761 tttaaccctc tttccagaga tgttttctcc actggagcac tcaatcgttg gaaaggctcg
    17821 agaaaaaggg ctcttggata tccagtatca taattttcga gaaaatgctg aaaaggcccg
    17881 tcatgtagat gatgagccct acggaggcgg tcagggcatg ttgctcagag tacaacctat
    17941 tttcgattcc tttgatgcta ttgaaaagaa aaatccgcgc gttattctcc tcgatcctgc
    18001 tggaaagcag tttgatcagg cttatgctga agatttggct caagaggaag agctaatctt
    18061 tatctgtggg cactatgagg gttatgatga gcgcattaag accttggtaa cagatgagat
    18121 ttccctaggc gactatgtcc tcactggtgg agaattggca gctatgacca tgattgatgc
    18181 tacagttcgc ctgattccag aagtgattgg caaggagtct agccaccaag atgatagttt
    18241 ttcttcaggt cttttagaat atcctcagta cacacgtcct tatgattatc gaggcatggt
    18301 cgtgccagat gtattgatga gtggccacca tgaaaagatt cgtcagtggc gattgtacga
    18361 gagtttaaag aaaacctacg agcgcagacc ggatttactt gaacattatc aactgacagt
    18421 agaagaagaa aaaatgctgg cagaaatcaa agaaaacaaa gaataaagga gaaacctatg
    18481 caagtaatca aacgtaatgg cgaaattgct gaatttaatc cagataagat ttaccaagcc
    18541 atcttgaagg cagcccaaac tgtttatgtt ttgacagatg atttgcgtca aaatcttgct
    18601 caagtcacta agaaggtagt tttggattta caagaagcca aggtggaacg tgcgactatc
    18661 agtatgattc aatctatggt tgaacatcgt ttattgggcg caggttacat taccattgca
    18721 gaacactaca tttcctatcg tttacaacgt gacttggaaa gaagtggtta tggagatcat
    18781 atcgcagttc atttacattt tgaacaaatt cgctaagaaa aaagagtggg atgaagcaac
    18841 tacatctcac tctttcttaa atctattttt ttgggctgtt tggacagttg aggggacaaa
    18901 tcgcaggcgt tgaatatcgc ttatacggat aatccggctc acatttttgg aaaaattttt
    18961 cacgataatt tgctggcctt gctgatcata tttgatgatg tcacctgtaa agcttgtctc
    19021 agataagata aggtgaacag cggtttgttt ctggatagcc tcttcaatag tggctgtaag
    19081 ggagttggtt tcagtctggt caggttggtc atatccattt aaaaaatcat gtattttatt
    19141 tagaacttgc tggaatttat gtctcatatt ggcctccctt cttttatatc aatattatat
    19201 aaaattttcc taaaatctac aagattttac gaataaacta atgaaactaa aaaaggagaa
    19261 gaaaatggca gaatttacat ttgaaatcga agagcacttg ttgactcttt ctgaaaacga
    19321 aaaaggttgg accaaggaaa ttaaccgtgt gagctttaat ggtgcccctg caaagtttga
    19381 tattcgtgct tggagtccag accatactaa aatgggcaaa gggattactc tctcaaatga
    19441 agaatttcaa acgatggtgg atgcctttaa aggcaactaa tactcttcga aaatctcttc
    19501 aaaccgcgtc agctttgcct tgccgtatgt atggttactg acttcgtcag tttcatccac
    19561 aacctcaaaa caatgttttg agctgacttc gtcagtttca tccacaacct caaaacagtg
    19621 tttttagcag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataagtt
    19681 ttcaaaataa aagaaaagga tattgagtca tgataactcg gtatcctttt ttagttagta
    19741 aagtaagcct gatttttaag gcgttgaagt aggggacggc taataaaact aatagccaga
    19801 agtttgccaa ggtctggaat gataaaggga agaaccccca caacaagagc tttttcaaat
    19861 gccattccag ctaggaaatg caagctgaga atcccgccga caaagacaag ggcatcaccc
    19921 aagaggtttg caagaaaaat cttaacaaca ccactcttgc tgttggttag agaggaagta
    19981 agtccagagt aaacgagata aaaccaaaga tagcctgcag tagggccaac taaaacctga
    20041 aaaccagctc cacctcctgc aaagacagga agaccgatag cacctagaag aagatagagt
    20101 ccagcagaaa gtacagcctc tctcggtcta aagacagtag caatcaagcc gattgcaaag
    20161 ttttgcagag tgaagggaac aggtccaatt ggaagactga tttgtgccaa agcagcaatg
    20221 agagcagccc caatagcagg gatagcataa acgtgagctt ttttcaaaat agttaacctc
    20281 ttttctaatg tatagtaact attatactca tataggagtc gatgtcaacc attttttaaa
    20341 aacaaggtaa caaaaactgt aacagccgat tttcgtgact agtcaagttg gataattttt
    20401 ttgttgattc gaaaatcatt aaaaaagaag cagacatatt tatatcagct tcttttgttt
    20461 cgattaacgc atggttacaa attcttcaga tgcagttggg tgaattgcca cagttgcatc
    20521 aaagtcagcc ttggttgctc ccattttgat agcaacggca aatccttgaa tcatttcatc
    20581 aacgccgtag ccaattccat gaagtccgac aactttttct tctgaaccag ctgttatgag
    20641 tttgaaacgg gattcttgac ggttgcgagt gcaagcagag tacatagatg caaagcttga
    20701 tttataaacc ttgatttggt cttgaccgta ttctttaata gcttgctctt ctgtcaaacc
    20761 aacagttccg atagcagggt gtgaaaagac aacagttgga atagttgagt aatccatttt
    20821 tgcagtagtt tttccgttaa agagacgttc agatagggta cgtccggcct tgattgcaac
    20881 tggagtcagt tctttctcgc ccgttacatc acctagagca tagattccct caacaacagt
    20941 attttggtat tcatccactt ggataaagcc acgttcgttc agagtcactc cagctttttc
    21001 aagttgcaag cccttaacgt ttggacggcg acctgtagcc cagataactt ggctagctgt
    21061 gtgactagta ccatcttcga aatgaatggt aatgccgtca gtagtttttt ctaacttgac
    21121 agggactttg tgagtgtgaa gtggtaagtt tgttctttcc atttccttga ccaaaccttc
    21181 aacgatgtag gaatcaaaac cacgtaaagg acgatcgcgg cgaacaaaga gatctgtctt
    21241 gacaccaaaa gtgtggagta cgccagctaa ttcaacggcg atataaccag cgcctagaat
    21301 ggcaattgac tctggaagtt cttcccaggc aaatacatca tcagaagagc cacctagctc
    21361 agcaccagga atattaggaa tacttggatg ggcacctgta gcaatcacga tatgtttagc
    21421 acgaatcagt tcaccattta cgcttacagt atgagaatct acaaattcag catgaccttc
    21481 aatcaagtct acaccgttgc gtttaaaact accatcataa gaagaacgag cgcgatcaat
    21541 gtaggcttca cgattgcgac gtagggttgc aaagtcaaag ttaagatcag tagtcttaaa
    21601 gccgtagtct tctccaaatt gatggaaagt ctcagcgatt tgcgccccgt accacatgat
    21661 ttttttagga acacaaccga cgttgacaca ggttccacct aatttctttt cctcaataac
    21721 ggctgctttg gctccatgtt caccagcacg gttcatggta gcgattcctc cgctacctcc
    21781 accgatagca atgatatcat attctctcat tgaaaactcc tttgtaatct tttaaatagt
    21841 agagcgtctt ttttgatagt tatattttat tctttttttg atttgattgc aaaaatctgc
    21901 tacgcacaaa aaattgcaaa aaagcttgcc aaataagtca agatagtgta ttatatatct
    21961 agtacaatag aaaaacaaaa ttccgaacga ttgtttaatc ctgaactgta ttgtttgctg
    22021 gagggaaatt tggtataata gcaaagtatt gtaaaaaaga aaaggagttt cattatgaag
    22081 aaaaagaatg gtaaagctaa aaagtggcaa ctgtatgcag caatcggtgc tgcgagtgta
    22141 gttgtattgg gtgctggggg gattttactc tttagacaac cttctcagac tgctctaaaa
    22201 gatgagccta ctcatcttgt tgttgccaag gaaggaagcg tggcctcctc tgttttattg
    22261 tcagggacag taacagcaaa aaatgaacaa tatgtttatt ttgatgctag taagggtgat
    22321 ttagatgaaa tccttgtttc tgtgggcgat aaggtcagcg aagggcaggc tttagtcaag
    22381 tacagtagtt cagaagcgca ggcggcctat gattcagcta gtcgagcagt agctagggca
    22441 gatcgtcata tcaatgaact caatcaagca cgaaatgaag ccgcttcagc tccggctcca
    22501 cagttaccag cgccagtagg aggagaagat gcaacggtgc aaagcccaac tccagtggct
    22561 ggaaattctg ttgcttctat tgacgctcaa ttgggtgatg cccgtgatgc gcgtgcagat
    22621 gctgcggcgc aattaagcaa ggctcaaagt caattggatg caacaactgt tctcagtacc
    22681 ctagagggaa ctgtagtcga agtcaatagc aatgtttcta aatctccaac aggggcgagc
    22741 caagttatgg ttcatattgt cagcaatgaa aatttacaag tcaagggaga attgtctgag
    22801 tacaatctag ccaacctttc tgtaggtcaa gaagtaagct ttacttctaa agtgtatcct
    22861 gataaaaaat ggactgggaa attaagctat atttctgact atcctaaaaa caatggtgaa
    22921 gcagctagtc cagcagccgg gaataataca ggttctaaat acccttatac tattgatgtg
    22981 acaggcgagg ttggtgattt gaaacagggt ttttctgtca acattgaggt taaaagcaaa
    23041 actaaggcta ttcttgttcc tgttagcagt ctagtaatgg atgatagtaa aaattatgtc
    23101 tggattgtgg atgaacaaca aaaggctaaa aaagttgagg tttcattggg aaatgctgac
    23161 gcagaaaatc aagaaatcac ttctggtttg acaaatggtg ctaaggtcat cagtaatcca
    23221 acatcttcct tggaagaagg aaaagaggtg aagactgatg aagcaactaa ttagtctaaa
    23281 aaatatcttc agaagctacc gtaatggtga ccaagaattg caggttctca aaaatatcaa
    23341 tctagaagtg aatgagggtg aatttgtagc catcatggga ccatctgggt ctggtaagtc
    23401 cactctgatg aatacgattg gcatgttgga tacaccaacc agtggagaat attatcttga
    23461 aggtcaagaa gtggctgggc ttggtgaaaa acaactggct aaggtccgta accaacaaat
    23521 cggttttgtc tttcagcagt tctttcttct atcgaagctc aatgctctgc aaaatgtaga
    23581 attgcccttg atttacgcag gagtttcgtc ttcaaaacgt cgcaagttgg ctgaggaata
    23641 tttagacaag gttgaattga cagaacgtag tcaccattta ccttcagaat tatctggtgg
    23701 tcaaaagcaa cgtgtagcca ttgcgcgtgc cttggtaaac aatccttcta ttatcctagc
    23761 ggatgaaccg acaggagcct tggataccaa aacaggtaac caaattatgc aattattggt
    23821 tgatttgaat aaagaaggaa aaaccattat catggtaacg catgagcctg agattgctgc
    23881 ctatgccaaa cgtcagattg tcattcggga tggggtcatt tcgtctgaca gtgctcagtt
    23941 aggaaaggag gaaaactaag atgcagaatc tgaaatttgc cttttcatct atcatggctc
    24001 acaagatgcg ttctttgctt actatgattg ggattattat cggtgtttca tcagttgttg
    24061 tgattatggc tttgggtgat tccctatctc gtcaagtcaa taaagatatg actaaatctc
    24121 agaaaaatat tagcgtcttt ttctctccta aaaaaagtaa agatgggtct tttactcaga
    24181 aacaatcagc ttttacggtt tctggaaagg aagaggaagt tcctgttgaa ccgccaaaac
    24241 cgcaagaatc ctgggtccaa gaggcagcta aactgaaggg agtggatagt tactatgtaa
    24301 ccaattcaac gaatgccatc ttgacctatc aagataaaaa ggttgagaat gctaatttga
    24361 caggtggaaa cagaacttac atggacgctg ttaagaatga aattattgca ggtcgtagtc
    24421 tgagagagca agatttcaaa gagtttgcaa gtgttatttt gctagatgag gaattgtcca
    24481 ttagtttatt tgaatctcct caagaggcta ttaacaaggt tgtagaagtc aatggattta
    24541 gttaccgggt cattggggtt tatactagtc cggaggctaa aagatcaaaa atatatgggt
    24601 ttggtggctt gcctattact accaatatct cccttgctgc gaattttaat gtagatgaaa
    24661 tagctagtat tgtctttcga gtgaatgata ccagtttaac cccaactctg ggtccagaac
    24721 tggcacgaaa aatgacagag cttgcaggct tacaacaggg agaataccag gtggcagatg
    24781 agtcccttgt atttgcagaa attcaacaat cgtttagttt tatgacgacg attattagtt
    24841 ccatcgcagg gatttctctc tttgttggag gaactggtgt catgaacatc atgctggttt
    24901 cggtgacaga gcgcactcgt gagattggtc ttcgtaaggc tttgggtgca acacgtgcca
    24961 atattttaat tcagtttttg attgaatcca tgattttgac cttgttaggt ggcttaattg
    25021 gcttgacaat tgcaagtggt ttaactgcct tagcaggttt gttactgcaa ggtttaatag
    25081 aaggtataga agttggagta tcaatcccag ttgccctatt tagtcttgca gtttcggcta
    25141 gtgttggtat gatttttgga gtcttgccag ccaacaaggc atcgaaactt gatccaattg
    25201 aagcccttcg ttatgaatga gatcaacaag atggacactc gtctatcttg tttttgtatg
    25261 gatttcccta tcgaaattca ttaaaaatgt gatataatga agtgttagaa aaacaggttt
    25321 catttgcctg gaaaggaaaa attatgtctg aaaaaaattt ttatattaca acgccgattt
    25381 actatccatc tgggaaactt catatcggtt ctgcctacac aactatcgca tgtgatgtcc
    25441 tagcacgtta caaacgcctg atgggctacg atgtatttta tctgacaggt cttgatgaac
    25501 atggtcagaa aatccagcag aaagcggaag aagctggtat tacacctcaa gcctatgttg
    25561 atggaatggc ggttggagtt aaagaactct ggcaattact agatatctca tacgataaat
    25621 ttatccgtac aactgatgac taccatgaaa aagttgttgc acaggtcttt gaacgcttac
    25681 ttgctcaaga tgatatctac ttgggtgaat actctggttg gtattcagta tcagacgaag
    25741 aattctttac agaaagccag ctggcagaag ttttccgtga tgaagctgga aatgtgactg
    25801 gtggtattgc tccatcaggt catgaggttg aatgggtttc tgaagaatca tacttccttc
    25861 gccttagcaa ataccaagac cgtttggtcg aatttttcaa agctcatcct gaatttatca
    25921 cgccagatgg tcgccttaat gaaatgctac gcaacttcat cgagccaggt ttggaagatt
    25981 tggcggtatc tcgtacaacc tttacatggg gagtgcctgt cccatcaaat ccaaaacacg
    26041 ttgtctacgt ttggattgat gcccttctta actatgcgac agctcttggc tacgctcaag
    26101 acgaacatgg taactttgac aagttctgga atggaacagt cttccatatg gtaggaaaag
    26161 atatccttcg cttccactct atctactggc caatccttct tatgatgttg gatgttaaat
    26221 tacctgatcg tttgattgcc catggttggt ttgtcatgaa agacggaaaa atgtctaagt
    26281 caaaagggaa tgtcgtttac cctgaaatgt tggtagagcg ttatggacta gatccacttc
    26341 gttactacct catgcgtaac cttccagttg gttcagacgg aacctttact cctgaagact
    26401 atgtcggccg tatcaactat gaattggcta atgaccttgg gaacctcctt aaccgtacgg
    26461 tttccatgat taataagtac tttgatggac aaatccctgc ctatgtagaa ggtgtgactg
    26521 aatttgatca tgttcttgct gaggttgcag aacaatcaat cgcagacttc catacacaca
    26581 tggaagcagt tgactatcca cgtgcgcttg aagcagtctg gactctgatc tctcgtacca
    26641 ataaatacat cgatgagact gcaccatggg tcttggacaa ggatgaagct cttcgtgacc
    26701 aattggcaag tgtcatgagc cacttggcag ccagcattcg tgtagttgct cacttgattg
    26761 aaccatttat gatggaaact agtcgtgcag ttttgactca acttggtttg gaagaagttt
    26821 ctagtcttga aaacttgagt ttggctgact tcccagcaga tgtgactgta gttgccaaag
    26881 gaacacctat ctttccacgt ctaaatatgg aagaagaaat cgcctatatc aaggaacaaa
    26941 tggaaggcaa taaaccagca gtcgaaaaag aatggaatcc ggacgaagtt gagctcaaac
    27001 taaacaagga tgaaatcaag tttgaagact ttgacaaggt tgaaatccgt gtcgcagaag
    27061 tcaaagaagt gtctaaagta gaaggttcag ataagttgct tcaattccgc ttggatgctg
    27121 gtgatggaga agatcgtcag attctttcag gaattgcaaa atactatcca aatgaacaag
    27181 aattggtcgg caagaaagtt caaatcgttg ctaacctcaa accacgtaaa atgatgaaaa
    27241 aatatgtcag ccagggtatg attctctcag ctgaacatga tggcaaatta acccttctca
    27301 cagttgatcc agctgtacca aatggaagtg tgattgggta aaagtagaca ggactagttc
    27361 aggctagttc tgttttttta tttatactca atgaaaatca aagagcaaac taggaagcta
    27421 gccgcaggtt gctcaaaaca ctgttttgag gttgtagata gaactgacga agtcagctca
    27481 aaacatg
//
LOCUS       DAVMAH010000031        27058 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVMAH010000031 DAVMAH010000000
VERSION     DAVMAH010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27058
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.031"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(562..654)
                     /locus_tag="VYO94_001241"
     CDS             complement(562..654)
                     /locus_tag="VYO94_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV1759879.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            815..1786
                     /gene="ruvB"
                     /locus_tag="VYO94_001242"
     CDS             815..1786
                     /gene="ruvB"
                     /locus_tag="VYO94_001242"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV1759880.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYGGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            1767..2339
                     /locus_tag="VYO94_001243"
     CDS             1767..2339
                     /locus_tag="VYO94_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV1759881.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLKKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            2570..3328
                     /locus_tag="VYO94_001244"
     CDS             2570..3328
                     /locus_tag="VYO94_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV1759882.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            3337..4140
                     /locus_tag="VYO94_001245"
     CDS             3337..4140
                     /locus_tag="VYO94_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV1759883.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            4162..5421
                     /gene="rseP"
                     /locus_tag="VYO94_001246"
     CDS             4162..5421
                     /gene="rseP"
                     /locus_tag="VYO94_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV1759884.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            5434..7287
                     /locus_tag="VYO94_001247"
     CDS             5434..7287
                     /locus_tag="VYO94_001247"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV1759885.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            7386..8765
                     /gene="bglA"
                     /locus_tag="VYO94_001248"
     CDS             7386..8765
                     /gene="bglA"
                     /locus_tag="VYO94_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1759886.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            8957..10765
                     /gene="glmS"
                     /locus_tag="VYO94_001249"
     CDS             8957..10765
                     /gene="glmS"
                     /locus_tag="VYO94_001249"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV1759887.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQVFDLVHELSIVAQSIESTLSEKET
                     IEVKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            10884..11933
                     /locus_tag="VYO94_001250"
     CDS             10884..11933
                     /locus_tag="VYO94_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV1759888.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIIAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(12033..15830)
                     /gene="spuA"
                     /locus_tag="VYO94_001251"
     CDS             complement(12033..15830)
                     /gene="spuA"
                     /locus_tag="VYO94_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV1759889.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNYRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGDRGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDTASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYRTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENISATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            16247..16660
                     /gene="rpsL"
                     /locus_tag="VYO94_001252"
     CDS             16247..16660
                     /gene="rpsL"
                     /locus_tag="VYO94_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV1759890.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16680..17150
                     /gene="rpsG"
                     /locus_tag="VYO94_001253"
     CDS             16680..17150
                     /gene="rpsG"
                     /locus_tag="VYO94_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV1759891.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            17575..19656
                     /gene="fusA"
                     /locus_tag="VYO94_001254"
     CDS             17575..19656
                     /gene="fusA"
                     /locus_tag="VYO94_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV1759892.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            19760..24151
                     /locus_tag="VYO94_001255"
     CDS             19760..24151
                     /locus_tag="VYO94_001255"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV1759893.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLDRLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLFPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            24253..24516
                     /locus_tag="VYO94_001256"
     CDS             24253..24516
                     /locus_tag="VYO94_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV1759894.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQVLTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            24509..24787
                     /locus_tag="VYO94_001257"
     CDS             24509..24787
                     /locus_tag="VYO94_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV1759895.1"
                     /translation="MLKIRYHKQFKKDFKLTMKRGLKAELLEEVLNFLVQEKEHPTRY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            24808..24960
                     /locus_tag="VYO94_001258"
     CDS             24808..24960
                     /locus_tag="VYO94_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759896.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGLF
                     SALKEK"
     gene            24982..26223
                     /locus_tag="VYO94_001259"
     CDS             24982..26223
                     /locus_tag="VYO94_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV1759897.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(26277..>27058)
                     /locus_tag="VYO94_001260"
     CDS             complement(26277..>27058)
                     /locus_tag="VYO94_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV1759898.1"
                     /translation="SEYVKDIPNKNQFIVKDITGKHAHLAHFENTSQHDYKRDKHKKT
                     LNQSNVYSTSLQVVRRASEEPIHYLCKYFGITATEESLKQLEEIGENISRMENTIDNL
                     YQREKQIKTDFNPPKFILKYFSKDLMKELDIHLPDIKVDYTSYIFEYVSAGGNSSQKT
                     TILFNGETVEATAEYIAKKIKSKQTAQAQRSLMTNKLRTQIKERDHYTCQICAASTAE
                     QSLLLLEIDHIVPVSKGGLSTPDNLQTLCWKCNRSKSNKIL"
BASE COUNT         7611 a         5136 c         6321 g         7990 t
ORIGIN      
        1 acctcctaac tttatttaat aaaatcctaa acttttcttt ttcataataa tctcccttaa
       61 ctccacccaa tcaggtggag ttttttagct ctatttcagg cttttgggga ctattctaaa
      121 aataattttt cgatattttt cggtattttt cggattttgg tcggggaatt ggcggggact
      181 tttttagcga atataactaa gaaataggtc tgtggtcgct tcagctagtt caaactcaat
      241 ttgattgtaa gtgactgtta attgaagaac tggaactact gtaataatga ttttgcttgt
      301 ctagtagtgg cgtattaaat gagaagtgac atgtaagatt gtctcttcgt ttacgaaatc
      361 aaaatttcta tgaaattgat agaatcccta acgttctctt aatcttaacc gtcttgtcgt
      421 acagcggttg aagaaaatgt aaacctttga caaaattcgt gaactatggg ataataaaaa
      481 ggaattgagt actagttcta tatcataggc tagaaaagac tccaagctca cgaccaaata
      541 agcttgaggt cttttttgac actatttgtc cttgtttagc catttatcga ctatacgaag
      601 aacgacaccg accacaattg gtccgatgat agttttgagt actaattcca tcatgggcta
      661 tctcacctcc tttcgtaggc ggtgtagcag tgtcgtagaa tattatacca cataagtgct
      721 aaacttagga gtcacccaat caggtggctt ttttgtttgt ggcttggttt tttgatataa
      781 tagagccatg agtagaattt tagataatga gataatgggg gatgaggagt tagtagaacg
      841 cacgctccgt cctcagtatt tacgtgaata tatcggacag gataaggtca aggaccagct
      901 acaaatcttt attgaagctg ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt
      961 tgggcctcca ggtctcggga aaacgaccat ggcctttgtt attgccaacg aactgggagt
     1021 caatcttaag cagacgtcgg gtccagtcat tgaaaaagcc ggagatctgg tagctatttt
     1081 gaatgagtta gagcctgggg atgtactttt tattgatgag atccatcgtt tgccaatgtc
     1141 agtggaagag gtgctttata gtgctatgga ggacttctac atcgatatta tgattggggc
     1201 tggtgagggt agtcgtagtg ttcatttgga gttaccacct tttaccttga ttggtgcgac
     1261 gactcgggct ggtatgctct ccaatccgct acgggcacgt tttgggatta caggccatat
     1321 ggagtattat gcccatgctg acttgacaga aattgtcgag cggacggcag atatttttga
     1381 gatggaaatc actcatgagg cagcatctga gttggcccta cgtagtcgtg ggacccctcg
     1441 tattgccaat cgtctcctca agcgcgtgcg cgattttgcc cagataatgg ggaatggggt
     1501 aattgatgat attattaccg ataaggcttt gactatgctg gatgttgacc atgaaggttt
     1561 ggactatgtg gatcaaaaaa tccttcgcac catgattgag atgtacggtg gtggccctgt
     1621 cggattagga actctttctg tcaatattgc cgaggagcgt gagactgtag aagacatgta
     1681 tgagccttac ttgattcaaa aaggttttat catgcggaca cggtctggac gggtggcgac
     1741 tgctaaggca tatgagcact taggttatga atacagtgaa aaataagcaa gaaatcttag
     1801 aggcttttag agaaaatcca gatatgatgg ccattctgac gatcatccga gaccttggtc
     1861 tgaaagactc gtggttggca gcaggttctg tcagaaattt catttggaat cttttgtcag
     1921 acaaatcccc ttttgatcat gaaacagata tagatgtgat tttctttgat ccagattttt
     1981 cttatgagga aaccttatta ctgaagaaaa agctgagaga ggattttcct cagtaccagt
     2041 gggaattgaa aaatcaggtc tatatgcatc agcacagtcc tcacactgct tcctatacca
     2101 gttctcgtga tgctatgagt aagtatccag aacggtgtac ggcagttgga ctgcgcttga
     2161 atgaagaatc agattttgaa ctctatgtac cttatggttt ggaggatatt ttgaattttc
     2221 aagttcgtcc aactcctcat ttcttagaaa atgaagaccg aatggaactc tatcaaacac
     2281 gtttatccaa gaaaaattgg caggagaaat ggaaaaattt gatttttaaa aatacttaag
     2341 gaaactttaa gctagggagt gtacactaag ttcataagtt aagaagacct taacttaaac
     2401 tcctaaaact ttttcataat aatctcccta taaaaataaa gtcgcccaat caggcggctt
     2461 atttttttga caaatgggct tggtgcctga gaataaatag cttagtgata gaagaaaatg
     2521 gggaaatatg gtataatgaa acgatagatt tttgaatagg aataagatca tgtttggatt
     2581 ttttaagaaa gataaggctg tggaagtaga ggttccgaca caggttcctg ctcatatcgg
     2641 catcatcatg gatggcaatg gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg
     2701 acataaggcg ggcatggaag cattgcaaac cgtgaccaag gcagccaaca aactgggcgt
     2761 caaggttatt acggtctatg ctttttctac ggaaaactgg acccgtccag atcaggaagt
     2821 caagtttatc atgaacttgc cagtagagtt ttatgataat tatgtcccgg aactacatgc
     2881 gaataatgtt aagattcaaa tgattgggga gacagaccgc ctgcctaagc aaacctttga
     2941 agctttaacc aaggctgagg aattgactaa gaacaacaca ggattgattc ttaattttgc
     3001 tcttaactat ggtggacgtg ctgagattac acaggcgctt aagttgattt cccaggatgt
     3061 tttagatgcc aaaatcaatc caggtgacat cacagaggaa ttgattggta actatctctt
     3121 tacccagcat ttgcctaagg acttacgaga cccagacttg attatccgta ctagtggaga
     3181 attgcgtttg agcaatttcc ttccatggca gggagcctat agtgagcttt attttacgga
     3241 caccttatgg cctgattttg acgaagcggc cttgcaggaa gctattcttg cctataatcg
     3301 tcgtcatcgc cgatttggag gagtttagga ggaaatatga cccaggattt acagaaaaga
     3361 accttgtttg cagggattgc cctggctatt ttcctaccaa ttttaatgat tgggggcctc
     3421 ttgcttcaga tagcaatcgg aatcatagcc atgctagcca tgcatgaact tttgaagatg
     3481 agaggtctag agaccatgac gatggagggc ctcttgaccc tctttgcaac ctttgcattg
     3541 accattccct tggagaatta cctgactttt ttgccagttg atgggaatgt ggttgcctat
     3601 agtgttttga tttcaatcat gttaggaacg accgttttta gcaagtctta tacgattgag
     3661 gatgcggttt tccctcttgc tatgagcttc tacgtgggct ttggatttaa tgctttacta
     3721 gatgctcgtg ttgcaggttt ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca
     3781 gacagtggtg cctatcttgt tgggatgaac tatgggaaac gaaagttagc accaagggta
     3841 tcgcctaata aaacccttga gggtgccttg ggtggtattt taggagcaat tttagtaacc
     3901 attatcttta tgatagttga cagtacagtt gctcttccat atggaattta caagatgtca
     3961 gtctttgcta ttttctttag cattgctgga caatttggtg atttactaga aagttcgatc
     4021 aaacgtcatt ttggtgttaa ggattctggg aaatttatcc ctggacatgg tggtgttttg
     4081 gatcgtttcg atagtatgtt gcttgtattt ccaatcatgc acttatttgg actcttttaa
     4141 tcaaaagacg gaggaaacgc tatgctcgga attttaacct ttattctggt ttttgggatt
     4201 attgtagtgg tgcacgagtt cgggcacttc tactttgcca agaaatcagg gattttagta
     4261 cgtgaatttg ccatcggtat gggacctaaa atctttgctc acattggcaa ggatggaacg
     4321 gcctatacca ttcgaatctt gcctctgggt ggctatgtcc gcatggccgg ttggggtgat
     4381 gatacaactg aaatcaagac aggaacgcct gttagtttga cacttgctga tgatggtaag
     4441 gttaaacgca tcaatctctc aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg
     4501 acccagtttg attttgaaga caagctcttt atcaaaggat tggttctgga agaagaaaaa
     4561 acatttgcag tggatcacga tgcaacggtt gtggaagcag atggtactga ggttcggatt
     4621 gcacctttag atgttcaata tcaaaatgcg actatctggg gcaaactgat taccaatttt
     4681 gcaggtccta tgaacaattt tatcttaggt gtcgttgttt tttgggtttt aatctttatg
     4741 cagggtggtg tcagagatgt tgataccaat cagttccata tcatgcccca aggtgccttg
     4801 gccaaggtag gagtaccaga aacggcacaa attaccaaga ttggctcaca tgaggttagc
     4861 aactgggaaa gcttgatcca agctgtggaa acagaaacca aagataagac ggcaccgact
     4921 ttggatgtga ctatttctga aaaggggagt gacaaacaag tcactgttac acccgaagat
     4981 agtcaaggtc gttaccttct aggtgttcaa ccgggggtta agtcagattt tctatccatg
     5041 tttgtaggtg gttttacaac tgctgctgac tcagctctcc gaattctctc agctctgaaa
     5101 aatctgattt tccaaccgga tttgaacaag ttgggtggac ctgttgctat ctttaaggca
     5161 agtagtgatg ctgctaaaaa tggaattgag aatatcttgt acttcttggc aatgatttcc
     5221 atcaatattg ggatttttaa tcttattccg attccagcct tggatggtgg taagattgtg
     5281 ctcaatatcc tagaagccat ccgccgcaaa ccattgaaac aagaaattga aacctatgtc
     5341 accttggccg gagtggtcat catggttgtc ttgatgattg ctgtgacttg gaatgacatt
     5401 atgcgactct tttttagata atcgaggaat attatgaaac aaagtaaaat gcctatccca
     5461 acgcttcgcg aaatgccaag cgatgctcaa gttatcagcc atgctcttat gttgcgtgct
     5521 ggttatgttc gccaagtttc agcaggtgtt tattcttatc taccacttgc caaccgtgtg
     5581 attgaaaaag ctaaaaacat catgcgccaa gaattcgaaa agattggtgc tgttgagatg
     5641 ttggctcctg cccttcttag tgcagaattg tggcgtgaat caggtcgtta cgaaacctat
     5701 ggtgaagacc tttacaaact aaaaaaccgt gaaaaatcag actttatctt aggtccaact
     5761 catgaagaaa cctttacagc tattgtccgt gattctgtta aatcttacaa gcaattgcca
     5821 ctcaaccttt atcaaattca gcccaagtat cgtgatgaaa aacgcccacg taatggactt
     5881 cttcgtacac gtgagtttat catgaaggat gcttatagtt tccacgctaa ctatgatagt
     5941 ttggatagtg tttatgatga gtacaaagca gcctatgagc gtattttcac tcgtagtggt
     6001 ttagacttca aggctattat tggtgacggt ggagccatgg gtggtaagga tagccaagaa
     6061 tttatggcca ttacatctgc tcgtacagac cttgaccgct gggttgtctt ggacaagtca
     6121 gttgcctcat ttgacgaaat tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc
     6181 aaatggatag tctctggtga agataccatt gcttactcaa gtgagtctag ctatgcagct
     6241 aacttagaaa tggcaacaaa cgagtacaaa ccaagcaacc gtgttgtcgc tgaagaagaa
     6301 gttactcgtg ttgcaacgcc agatgttaaa tcaattgatg aagttgcagc cttcctcaat
     6361 gttccagaag aacaaacgat taaaaccctc ttctacattg cagatggcga gcttgttgca
     6421 gcccttctag ttggaaatga ccaactcaac gaagtcaagt tgaaaaatca cttgggagca
     6481 gatttctttg acgttgctag cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt
     6541 tcacttggac cagttggttt gccagagaat attaaaatta ttgcagatcg taaggtacaa
     6601 gatgttcgca atgcagttgt cggtgctaac gaagatggct accacttgac tggtgtgaac
     6661 ccaggccgtg attttactgc agaatatgtg gatatccgtg aagttcgtga gggtgaaatt
     6721 tccccagatg gacaaggtgt ccttaacttt gcgcgtggta ttgagatcgg tcatattttc
     6781 aaactcggaa ctcgctattc agcaagcatg ggagcagatg tcttggatga aaatggtcgt
     6841 gctgtgccaa tcatcatggg atgttacggt atcggtgtca gccgtcttct ttcagcagtg
     6901 atggagcaac acgctcgcct ctttgttaac aaaacgccaa aaggtgaata ccgttacgct
     6961 tggggaatca atttccctaa agaattggca ccatttgatg tgcatttgat tactgtcaat
     7021 gtcaaggatg aagaagcgca agccttgaca gaaaaacttg aagcaagctt gatgggagct
     7081 ggttatgaag tcttgacaga tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt
     7141 gacttgattg gtcttccaat ccgtatcact gttggtaaaa aagcggccga tggcattgta
     7201 gaagttaaga tcaaggcaac tggtgacacc attgaggttc atgcagataa cgtgcttgaa
     7261 acgcttgaaa tcctaagcaa gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat
     7321 gtaactagtt tttaccttgt tttttctgta taatgggaga aatgagtaga taaagaggta
     7381 aatgtatgct aagatttcca aaggattttg tctggggatc ctctacttct ggaccgcaga
     7441 cagaaggacg tgtagctggt gacggtaagg gagacaatct ctgggattac tggttccaag
     7501 tggagccaaa tcgttactat aatgggattg gttcagataa gacatcgact ttttatgaaa
     7561 attgggagcg ggatattgag cttttgttag agactggtca cacagccttt cggacttcta
     7621 ttcagtggtc acggattttt ccacaaggct gtggaaaagt caaccctcaa ggtgtggatt
     7681 tttatcgtaa ggtctttgag gctattaagg ctaaaggaat tcgtctgtta gtcaatctct
     7741 atcattttga tttacctttt gcccttcaag aggatggtga tggttgggaa aataaggcga
     7801 cagtctcagc ctatgaagac tatgctcgtt tttgttttga gacttatgga gatttagtgg
     7861 atcaatggat tacctttaac gagcccatcg ttcctgtaga atttggttat ttttatgatg
     7921 cccattatcc acataaggtg gatgcagagg cagctgttaa ggtagcctat catacacaat
     7981 tggccagcag ccgggctgtt aaggcttgcc atgaactttt gcctgattcc aagattggga
     8041 ttgtcctcaa cttgacaccg gcttatccac gtagccagca tcctgctgat gtcaaggcag
     8101 ctcgtattgc ggcccttttt caggcccaat ctttcttaga tccatctgtc ttggggactt
     8161 atccacagga gttggtagaa atcttgcatg aacacggtct tttacctgat gctacagagg
     8221 aagagttgga actcattcgt gataatacgg tggacttcct tggtgtgaac tactatcaac
     8281 ctttgcgtgt tatggctcct cgatttgcta agcatccaga gagtccactc ttaccagaac
     8341 atttttacga gccttatgtg atgcctggac gtaaaatcaa ttctcaccgt ggttgggaga
     8401 tttatgagca agggatttat gacatcgccc aaaatatcaa ggaaaattat ggcaatattg
     8461 aatggatgtt gactgagaat ggtatgggtg ttgaagggga agaaaaattc cgtcaagatg
     8521 gaatgattca agatgattac cgtattgact ttgtaaaagg tcatcttcgt gaacttcacc
     8581 gtgccattga agatggtgcc aactgtaagg gctacttgat ttggaccttt attgactgct
     8641 ggtcatggct caacagctat aaaaatcgct atggtttggt cgaattagac ttggaaacgc
     8701 aagaacgtcg tctgaagaaa tcaggccact ggttcaaaaa attaagcgat aataatggat
     8761 tttaaaaagg actctgactg attatcccaa tcggtcagag ttttttgctt acaggagctt
     8821 aatttgaact ataccaattt ttactcttga caagtgaaag aaacaagtat atactgtttt
     8881 tgctgattct ataaaagatg aattagacta taccaatttt aaggagaaag cacagcttgc
     8941 ctgtgtcgta tatactatgt gtggaattgt tggtgttgtt ggaaacacaa atgcaactga
     9001 tattttgatt caagggcttg aaaagcttga ataccgtggc tatgattctg cgggaatttt
     9061 tgtcctagat ggtgctgata accatttggt gaaggcggtt ggtcgtattg cagaattgtc
     9121 tgccaagaca gctggtgttg agggaacaac tggtatcgga catactcgtt gggctactca
     9181 cggaaaacca actgaggaca atgctcaccc acaccgctct gagacagaac gttttgtctt
     9241 ggtgcataat ggggtgattg agaactacct tgaaatcaag gaagaatacc ttgcaggtca
     9301 ccacttcaag gggcagacag atactgaaat agccgttcat ttgattggaa aatttgcgga
     9361 agaagaaggg ctctcagttc ttgaagcctt caaaaaagcc cttcacatca tccgtggttc
     9421 ttatgccttt gccttggttg actcacaaga tcctgaagtc atctacgtag ctaaaaataa
     9481 atcaccactt ttgattggtc ttggagaagg ctataacatg gtctgctcag acgccatggc
     9541 tatgattcgt gaaactaacc aatacatgga aatccatgac caagagttgg taatcgtcaa
     9601 ggctgatagt gtggaagttc aagactatga tggaaatcgt cgtgagcgtg ctagctacac
     9661 tgctgaactt gacttgtcag atatcggtaa gggaacttac ccttactaca tgctcaagga
     9721 aattgacgag caaccaactg ttatgcggaa actcatccaa gcctacacag atgaggctgg
     9781 tcaagttgtc gtagacccag atatcattaa ggctgttcaa gacgcagacc gcatctacat
     9841 ccttgcagct ggaacatctt accatgcagg atttgcttct aagaaaatgt tggaagaatt
     9901 gacagataca ccagttgaac ttggaatctc atctgagtgg ggctacggta tgccacttct
     9961 cagcaagaaa ccactcttca tctttatcag ccaatctggt gaaacagcgg atagtcgtca
    10021 agttttggtc aaggctaatg aaatgggaat tccaagctta acagtgacaa atgttccagg
    10081 ttcaaccctc tcacgtgaag ccaactatac catgctcctt catgcaggtc ctgaaattgc
    10141 tgtggcatca actaaagcct atacagcgca aatcgcagcc cttgccttcc ttgcaaaagc
    10201 agtcggagaa gcaaatggta atgctaaagc gcaagtcttt gatctggttc atgaattgtc
    10261 aatcgtagct cagtctatcg aatcaactct ttcagagaaa gaaaccattg aagtcaaggt
    10321 tcgtgaactt cttgaaacaa ctcgtaacgc cttttacatc ggacgtggtc aagattacta
    10381 cgtagccatg gaagcaagtc tcaaactcaa agagatttct tatatccagt gtgaaggctt
    10441 tgctgcagga gaactcaagc acggaaccat tgccttgatt gaagaaggaa cgcctgtttt
    10501 ggctctcttg tcagatccag ttcttgccaa ccatactcgt ggaaatatcc aagaggtcgc
    10561 agcccgtggt gccaaagtcc tcactatcgc agaagagaat gtagccaaag ataccgacga
    10621 tatcgtcctt acgaccgtac atccatacct ctcaccaatt tcaatggtcg taccaacgca
    10681 attagtcgct tactttgcaa ccctccaccg tggcctcgat gtggataaac cacgtaacct
    10741 tgctaaatca gtaacggtag aataagctaa aaaagtctag ttatctaggc tttttctaat
    10801 gagcaaattg gttgcttgta cttaagattc gtgttagaat aatttttcaa attgaaggac
    10861 agagatagac aaggagaatc acaatggtag aattgggaat ttcaacattt ggggaaataa
    10921 cggagcttga agggactgga caaacttaca gtcatgctga acgcattcgc cagttggtgg
    10981 cagagattga gctggctgac aaggttggtt tggacgtata tgggattggc gagcaccatc
    11041 gggcggattt tgcagtatca gccccagaga ttgtcctggc cgctggggca gtcaatacca
    11101 agaaaatccg tttgaccagt gcagtcagca ttctgtcaag catggacccg attcgtttgt
    11161 tccaacagta tgccactatc gatgctttgt caaatggacg atcggagatt atagctggaa
    11221 ggggctcttt cacggaatct ttccctctgt ttggttatga cttgaaagac tacgactctc
    11281 tttttgatga gaaattagac ttgcttcagt tagtcaatga aaagaccaag ttagactggc
    11341 aaggtcgatt gactcaaacg attgctggta aagaagttta tcctcgtcca gttcaggaca
    11401 aattgccctt gtggatagct acaggtggtc atgtcgaatc aacagtgaag attgctcagg
    11461 ctggtctacc gattgtatat gctattattg gtggtaatcc acgttatttt aaaaagttga
    11521 ttcaggctta tcgtgagatt ggaagcgaag cgggccatgc tgacaaagac ttgaaagtgg
    11581 gagcccattc ttgggggtgg attgcggaag atggtgagca ggcggtgaaa gattatttcc
    11641 atccgactaa gcaagtggtg gatgctattt ccaaagaccg tccgcactgg caggaattgc
    11701 gttatgagca atatttggag caggtagggc caaatggcgc catgtttgtt ggcaatccag
    11761 atcaggtggc cgaaaaattg attcgcatga tagaggattt aggattggac cgcttcatgc
    11821 ttcatctacc gcttggttct atgcctcatg accaggttct gagagctatt gaactcttcg
    11881 gaacacaagt tgcacccaaa gtacgagctt attttgctat gaaagaggct taataaaaaa
    11941 tcctaatcaa gtttattagg acaacaaata ttgtacgaaa attaatcccc cgagctataa
    12001 tgcttggggg atttttctat aggagggcta gcttagttct cttttttatt ttttagtaag
    12061 aaaccgagac caaggagcgc aaggaggctg attcctgcaa ataggagttt gttttcgttt
    12121 ttgattcctg tatttggaag ttcagcttgt ctatctgggg ttgcagatat attttccttg
    12181 ctagagtttt ctaccgattc gtttcgaacc gcttctttta cagatgatgc ttgtgcttct
    12241 tgtgctggtt gttcagcttg tgaatcagct gtagcttggc taggtttatt ttccgcatca
    12301 gctactttgg catctggttt agtagaatca ggtctagctt ctggagctgg gtcttgatgt
    12361 gcagggtgag aagcttcatt ttgatgttca ggcttggaag gggttgagtc tggtttctct
    12421 tctgcagttg actcatggct agttccattt tgagagactc gaagaacagt agctgtaagg
    12481 gcattcaatt tcaagccttt ttcagtccat tcaagtcctt tcgggttggc aattccgact
    12541 gatcctgctt ggttttcatc tgccaaaact tccgcatttc ttagatgtgc aaaggcagtt
    12601 cccaaattaa attcgcgagc tttttcatcc gcattgacaa agactgcgta gatatcgccg
    12661 tttggagcag tgatttgata gccaatcact acatcctctt tttccacacc attttggcct
    12721 gggacagtga tgaggtggac acggtctttg atatcttgaa gactcttaag tcggaaggca
    12781 tctgtagatt gacgaagggc aatcaaacct ttcatatagt cacggctctt gacattttca
    12841 ggataagctt taccatctgt agccttagtc cagtcaaact tgttgactgc atcactagaa
    12901 tcgtaagagt catggatgaa gtaaggatag tcaaatgggt tgccgtcctt atcacgcaac
    12961 aagtgagatt tgtttggaac cttatcctct gctacaggag ttctgtaggc tgggtcacgg
    13021 aattgtttgg tacgtccata ttcctggcca gagtggataa acggagttcc ttgagctgtc
    13081 aagaccatga gatttccaag tctcaaacga cggtggattt cagcatagtt ctcagccttg
    13141 cttgggtctt ttttgataga ctgggcaatg atgtcaaaga gggtcaagtt atcatgggct
    13201 gcgatgtatt ggatgacatc tccagggctg tcagcttcaa agttagttgg ttgagcaatg
    13261 agatttttaa agatggtgtt gacatcacgc ttgccacctg tgataaaggc aggttgacct
    13321 tcgtttggat aaccagattt gaggttgtta cggatgtcat ctgaaaagac agcgacagta
    13381 tcggtatgtt tcatccaatc ttggtcagca gctttagtag gcatgttttc atcaccggca
    13441 taggttctcc aaccttcacc aagcatgatg aggtttggat tgagggcgcg tgcagctttg
    13501 taagcttctt cgatagaagc ggtgtcatgg tctcccatca tatcgaaacg gaatccatcc
    13561 actttgtagg tatcaactag atatttgata gagtcaacta ggaggcgttt ggtcatatgg
    13621 tgggttgttc ccaagcgtcc accaccaaag ctagttcgag gtgtaccatc ggcatccata
    13681 aagtggtagt agtttggctc taggtcttca aagatatcga ctttggctgt gtggttataa
    13741 acgacatcta ggatagctcc cataccacgt ttgtggattt cgttgatgag gtttttaaat
    13801 tctgcgattc gtttttctgg attcttagga tcgcttgagt acataccagt caaggagaag
    13861 tagttttgag ggtcatatcc ccagttgtag ttgctgttgc ttgaagcata gtcagacaag
    13921 cgttcatggt ttttcaattc attgacaaag tagtaagaca agactggaag gagctggata
    13981 tgggttacac ccaagtcttt gagatagtct agtttttcaa tgaaggcttc aaaagtccca
    14041 aatggtttgg tcaagtcttt tgcaatggca ggatctgaag tgaagtcacg cacatgagct
    14101 tcgtagataa cggcgtcttc acgagtcttg aaattgtgaa tcttaccata agtcaagtct
    14161 tgaggtccga gtttagctgg atctacaaag gcggctttag ccactttatg ggcatcgtca
    14221 atcttggcat cgtcgctatt ccaagcagca agagatttag cgtaaggatc gagtgcaaga
    14281 acagttttac cttgacgctc gatttggtat tgataatagt agccagtgaa atctgtgatt
    14341 ccgagtttgt ttgtgctgtc tagagtttgt ttccaagttc ctctgtcccc tttttcgaga
    14401 gcgacagttc caactacttt gtcagggtca ttcttgtcgt agacaacaac agaaacctta
    14461 tcagcacttg gtgaccaaag ggtcaaatca acttgttttc cttcttcttt taggtcagct
    14521 cccagtttgc catcatagct gtatgtctca tctttcaggc gccagcttgt tttggtagtg
    14581 aattggtcgg aattgtagct aacagtataa ggatgttttg tgtcagagaa atctccgctg
    14641 taggtcactt tcttaccagc ttcatcgatt gcaacatcgg taatagttac cttgtttcct
    14701 aggtgattag tgatgttgga gtgtttgagg atatcttctt ttttagcacc gacaagtgtt
    14761 gaaaagctac tttcaatgct agaagtgcct acgtgttggg ctcctgtcat acggatatca
    14821 tggacatagt atggatttgt gtaaatcgat tcatcatcgt cttttaggaa aatttggcta
    14881 tgatttttca aatctgtgaa cttataattt tctttacgga ttttcacgtc gtctccttgt
    14941 ttgctctcat ctagtaataa aaatccaaat tctcttgcgg cttcattaag aggaatgtcg
    15001 atatagcggc catatttgcc tgtagccgta aagtctgttc cgtcaggcca ttgagcgcta
    15061 cttggatttt ttacatctcc ccagtaccag agagatttct tgtcatagtt gccatctgtg
    15121 cggtagtagt tgacgcgaac agttcctgca ggttgtggct cgtaagagaa aaccttgtaa
    15181 tcttggtcta accaagcctc gttcattttt ggaactagtt tttctacaga tttatcgccg
    15241 gttagatttt ttccagctgt attgttgatg aggaagctaa ttttcttggc ttgttctccc
    15301 tttaatttga catctaggta atagccgtag tcatctttct tggcatcctt gaaggacaaa
    15361 gctccgtttg gccagttttc agatggtttt tcaacatcgt cccaagtcca tagtccttga
    15421 gcatccttgt tttcttcagg aagttttttg acatggatac ggaagtagtt atcttcgatg
    15481 ggctcttctg ccttagtttc agttgttact ggactagtag aagtagttgg ctctgttgca
    15541 ggtttttctt ctgttttctc tagggaagcg tttgcatttc taggtgaaga aatatcactt
    15601 tcgttcttac cagagccagc agctgtatca gtaagaggtt gggcaagggt ggttgtattt
    15661 ctgtagttgg gttcgttagt ggttggtgta ctttcgtcgg atgagatagt tggtgtagcc
    15721 atggcaagca agacaaggct tgcgccgata aggacagaac cagttccatt tttgagggaa
    15781 cggatgctgt agaccatttt tttctcagtg tgagatggtg tttttctcat aatgattctc
    15841 caatcaataa atttctatat cagtatagca tgtagtaaaa caatatgcaa gcgttttctt
    15901 ttatttgtga aaaaaattct tacttttgag aagttttctg tactatttta tatgtcagta
    15961 taaatgacgg agataaaaat gtcacataag ccaagccgta ttattaggaa gatgatgtgt
    16021 tcccagctat ttttattcag aaattgatct ctaacattac caataaaaaa gaaaaatatc
    16081 ttgacaagca agggaaaatt ttgttacaat aatagacggt actttttact tttggtctct
    16141 caagagtgta cagggacgtg ctgacaaatg ttgcaaaagt acacacagat gatatctgtc
    16201 accaagtgta tcatcaccaa aaataaaaaa acacaggaga atgtagatgc ctacaattaa
    16261 ccaattggtt cgcaaaccgc gtaaatcaaa agtagaaaaa tctaaatcac cagctttgaa
    16321 cgttggttac aatagtcata aaaaagttca aacaaacgtt tcttcaccac aaaaacgtgg
    16381 tgttgcaact cgtgttggaa caatgacacc taaaaaacct aactcagccc ttcgtaaatt
    16441 cgctcgtgta cgtttgagca accttatcga agttactgcc tacatcccag gtatcggaca
    16501 caacttgcaa gagcacagcg tggtgcttct tcgcggtgga cgtgtaaaag accttccagg
    16561 ggtacgttac catatcgtcc gtggtgcact tgatactgca ggtgttaacg atcgtaaaca
    16621 aggccgttct aaatacggta ctaaacgtcc aaaagcataa ggaaagggga taaagagaaa
    16681 tgagtcgtaa aaatagagct ccaaaacgtg acgtattgcc agatccgcta tacaattcac
    16741 aactagttac tcgtcttatc aaccgcgtta tgcttgatgg taaacgtggt actgctgctt
    16801 caatcgttta cggtgctttt gagcaaatca aagaagctac tggcaacgat gcacttgaag
    16861 tatttgaaac agctatggaa aacatcatgc ctgtacttga agtacgtgca cgtcgtgttg
    16921 gtggttctaa ctaccaagtc ccagttgaag ttcgtccaga acgtcgtaca acacttggac
    16981 ttcgttggtt ggtaacaatc gctcgtcttc gtggtgaaca cacaatgcaa gaccgtcttg
    17041 caaaagaaat cttggatgct gctaacaaca ctggtgcagc tgttaagaaa cgtgaagata
    17101 ctcaccgtat ggctgaagct aaccgtgcat tcgcacactt ccgttggtaa gataggatgc
    17161 gaaagcgtta agaaagtccc agagaaaata gggaatcgaa gcaggttgcg attgcaacca
    17221 atgagattca tctttttctc cagactttta gcttgagctc aactaaatca tgatgctagg
    17281 cacggtaagg atgcaaggtg aaaataggaa actgacgcag tattcaacga atacaaggag
    17341 ttttatcttt ttcacgcagc atcccgttcc agctcacatc ggctaactaa ctttagccca
    17401 ggttcaaatt agctaaatcg attagtatta gctataactc agcttaccat ctcgtaagtt
    17461 gaaaccaaca atagcatgaa aacattgaga acgggtaggt cctgcctatc cgtttttatt
    17521 aaaatcgtgt tataatagaa tagaaatcaa aaataaatag gagaaacaaa cctcatggca
    17581 cgcgaatttt cacttgaaaa aactcgtaat atcggtatca tggctcacgt cgatgctggt
    17641 aaaacaacaa ctactgagcg tattctttac tacactggta aaatccacaa aatcggtgaa
    17701 actcacgaag gtgcgtcaca aatggactgg atggagcaag agcaagaacg tggtatcacg
    17761 atcacatctg ctgcgacaac agctcaatgg aacaaccacc gcgtaaacat catcgacaca
    17821 ccaggacacg tggacttcac aatcgaagta caacgttctc ttcgtgtatt ggatggtgcg
    17881 gttaccgttc ttgactcaca atcaggtgtt gagcctcaaa ctgaaacagt ttggcgtcaa
    17941 gcaactgagt acggagttcc acgtatcgta tttgccaaca aaatggacaa aatcggtgct
    18001 gacttccttt actctgtaag cacacttcac gatcgtcttc aagcaaatgc acacccaatc
    18061 caattgccaa tcggttctga agatgacttc cgtggtatca ttgacttgat caagatgaaa
    18121 gctgaaatct atactaacga ccttggtacg gatatccttg aagaagacat cccagctgaa
    18181 taccttgacc aagctcaaga ataccgtgaa aaattgattg aagcagttgc tgaaactgac
    18241 gaagaattga tgatgaaata cctcgaaggt gaagaaatca ctaacgaaga attgaaagct
    18301 ggtatccgta aagcgactat caacgttgaa ttcttcccag tattgtgtgg ttcagccttc
    18361 aaaaacaaag gtgttcaatt gatgcttgat gcggttatcg actaccttcc aagtccactt
    18421 gacatcccag caatcaaagg tattaaccca gatacagacg ctgaagaaac tcgtccagca
    18481 tctgacgaag agccatttgc agctcttgcc ttcaagatca tgactgaccc attcgtaggt
    18541 cgtttgacat tcttccgtgt ttactcaggt gttcttcaat caggttcata cgtattgaat
    18601 acttctaaag gtaaacgtga acgtatcgga cgtatccttc aaatgcacgc taacagccgt
    18661 caagaaatcg acactgttta ctcaggtgat atcgctgctg ccgttggttt gaaagatact
    18721 acaactggtg actcattgac agatgaaaaa tctaaaatca tccttgagtc aatcaacgtt
    18781 ccagaaccag ttatccaatt gatggttgag ccaaaatcta aagctgacca agacaagatg
    18841 ggtatcgccc ttcaaaaatt ggctgaagaa gatccaacat tccgcgttga aacaaacgtt
    18901 gaaactggtg aaacagttat ctcaggtatg ggtgaacttc accttgacgt ccttgttgat
    18961 cgtatgcgtc gtgagttcaa agttgaagcg aacgtaggtg cgcctcaagt atcttaccgt
    19021 gaaacattcc gcgcttctac tcaagcacgt ggattcttca aacgtcagtc tggtggtaaa
    19081 ggtcaattcg gtgatgtgtg gattgaattt actccaaacg aagaaggtaa aggattcgaa
    19141 ttcgaaaacg caatcgtcgg tggtgtggtt cctcgtgaat ttatcccagc ggttgaaaaa
    19201 ggtttggtag aatctatggc taacggtgtt cttgcaggtt acccaatggt tgacgttaaa
    19261 gctaagcttt atgatggttc atatcacgat gtcgactcat ctgaaactgc cttcaagatt
    19321 gcggcttcac tttcccttaa agaagctgct aaatcagcac aaccagctat ccttgaacca
    19381 atgatgcttg taacaatcac tgttccagaa gaaaaccttg gtgatgttat gggtcacgta
    19441 actgctcgtc gtggacgtgt agatggtatg gaagcacacg gtaacagcca aatcgttcgt
    19501 gcttacgttc cacttgctga aatgttcggt tacgcaacag ttcttcgttc tgcatctcaa
    19561 ggacgtggta cattcatgat ggtatttgac cactacgaag atgtacctaa gtcagtacaa
    19621 gaagaaatta ttaagaaaaa taaaggtgaa gactaatccg tcctcactct agaaggaagt
    19681 cacttagtgg cttccttttg tctttagaaa atacctctaa atatggtaaa atagtagaag
    19741 aataatgtga ggaaaatgaa tgtcaaatag ttttgaaatt ttgatgaatc aattggggat
    19801 gcctgctgaa atgagacagg ctcctgcttt agcacaggcc aatattgagc gagttgtggt
    19861 tcataaaatt agtaaggtat gggagtttca tttcgtattt tctaatattt taccgattga
    19921 aatcttttta gaattaaaga aaggtttgag cgaagaattt tctaagacag gcaataaagc
    19981 tgtttttgaa attaaggctc ggtctcaaga attttcaaat cagctcttgc agtcctacta
    20041 tagggaggct ttctctgaag gtccatgtgc tagtcaaggt tttaagtctc tttatcaaaa
    20101 tttgcaagtt cgtgctgagg gtaatcagct atttattgaa ggatctgagg cgattgataa
    20161 ggaacatttt aagaagaatc atcttcctaa tttagccaaa caacttgaaa agtttggttt
    20221 tccaactttt aactgtcaag tcgagaagaa tgatgtcctg acccaagagc aggaagaggc
    20281 ctttcatgct gaaaatgagc agattgttca agctgccaat gaggaagcgc tccgtgctat
    20341 ggaacaactg gagcagatgg cacctcctcc agcggaagag aaaccagtct ttgattttca
    20401 agcgaaaaaa gctgcagcta aacccaagct ggataaggcg gagattactc ctatgatcga
    20461 agtgacgaca gaggaaaatc gtctggtatt tgaaggggtt gtttttgatg tggagcaaaa
    20521 agtgactaga acaggtcgtg ttttaatcaa ctttaaaatg acggactata cttcaagttt
    20581 ttctatgcaa aagtgggtta aaaacgagga agaggcccag aagtttgacc tcatcaagaa
    20641 gaattcttgg ctccgagttc gagggaatgt ggagatgaat aacttcacac gcgatttgac
    20701 tatgaacgta caggatctgc aggaagttgt tcactatgag cggaaggatt tgatgccaga
    20761 aggtgagcgt cgggttgagt ttcatgctca tactaacatg tcgactatgg atgctttgcc
    20821 agaggtcgaa gagattgttg caacagctgc taagtgggga cacaaggcgg ttgctatcac
    20881 agaccatggg aatgtccagt cctttccaca tggctataag gcggctaaga aagcgggaat
    20941 ccagctgatc tatgggatgg aagccaatat cgtggaggac cgtgtcccta tcgtctataa
    21001 cgaagtggag atggacttat cagaagcaac ctacgtggtc tttgacgtgg aaacgacggg
    21061 actttcagct atctataatg acttgattca ggttgcggcc tctaagatgt acaaggggaa
    21121 tgttattgct gaatttgatg aatttatcaa tcctgggcat cccttgtcag cttttactac
    21181 agagttaact ggaattacag atgatcatgt caaaaatgcc aaaccactag aacaagtttt
    21241 gcaagaattc caagaatttt gcaaggatac ggtcctagtt gcccacaatg ctacctttga
    21301 cgttggcttt atgaatgcta attatgagcg tcatgatctt ccaaagatta gtcagccagt
    21361 tattgatacg ctggagtttg ctagaaacct ctatcctgag tataaacgcc atggtttggg
    21421 gcctttgacc aagcgttttg gtgtggcctt ggaacatcac cacatggcca actacgatgc
    21481 ggaagcgact ggtcgtctgc ttttcatctt tatcaaagag gtagcagaaa aacatggtgt
    21541 gaccgattta gatagactca acattgatct aatcagtcca gattcttaca aaaaagctcg
    21601 gatcaagcat gcgaccatct atgtcaagaa tcaggtaggt ctaaaaaata tctttaagct
    21661 ggtttccttg tctaatacca agtattttga aggagtgcca cggattccga gaacggttct
    21721 agatgcccat cgagagggct tgattttagg ttcagcctgt tcagagggtg aagtttttga
    21781 cgtggtcgtt tctcaaggtg tggatgcggc ggttgaggtg gccaagtatt atgactttat
    21841 cgaggtcatg ccaccggcta tctatgcgcc cttgattgcc aaagagcagg tcaaggatat
    21901 ggaggaactc cagaccatta tcaagagttt gatagaggtt ggagatcgcc ttggcaagcc
    21961 tgttctggct acgggaaatg ttcactatat cgaaccggaa gaagagattt atcgtgaaat
    22021 tatcgtccgt agtttgggac agggtgcgat gattaaccga actatcggtc atggtgaaca
    22081 tgcccaacca gcgccacttc caaaggctca ttttcgaacg actaatgaga tgttggatga
    22141 atttgccttt ttgggagagg aactggctcg taaactggtt attgaaaaca ccaatgcctt
    22201 ggcagaaata tttgaacccg ttgaagtcgt taagggtgac ttgtatacgc ctttcatcga
    22261 caaggctgaa gaaacagttg ctgagttgac ctataagaaa gcttttgaga tttatgggaa
    22321 tccgctgcca gatattgttg atttgcggat tgaaaaagaa ttaacatcca tactggggaa
    22381 tggatttgct gtgatttatt tggcatcgca gatgctggtg caacgttcta atgaacgggg
    22441 ttatttggtt ggttctcgtg ggtctgtcgg atctagtttc gttgcgacca tgattgggat
    22501 tacggaggtc aatcctctct ttcctcacta tgtctgtggt cagtgtcagt acagtgagtt
    22561 tatcacagat ggttcgtacg gttcaggatt tgatatgccc cataaggact gtccaaactg
    22621 tggtcacaaa ctcagtaaaa acggacagga tattccgttt gagaccttcc ttggttttga
    22681 tggggataag gttcctgata ttgacttgaa cttctcggga gaagatcagc ctagcgccca
    22741 cttggatgtg cgtgatatct ttggtgaaga atatgccttc cgtgcgggaa cggttggtac
    22801 agtagctgcc aagactgcct atggatttgt caagggttac gagcgagatt atggcaagtt
    22861 ttatcgtgat gcagaagtag aacgcctcgc tcaaggagcg gcgggtgtca agcggacaac
    22921 aggccaacac ccggggggaa tcgttgttat tccgaactac atggatgtct acgattttac
    22981 gcctgtccag tatccagcag atgatgtcac ggctgaatgg cagaccactc actttaactt
    23041 ccacgatatc gatgagaacg tcctcaaact cgatgtactg ggacatgatg atccgaccat
    23101 gattcgaaaa cttcaggatt tgtctggtat tgaccctaat aaaattccta tggatgacga
    23161 aggcgtgatg gcactctttt ctgggactga tgtgctaggg gtaacacctg aacaaattgg
    23221 aacgcctacg ggtatgttgg ggattccaga gtttggaaca aatttcgtac gtggaatggt
    23281 agacgaaacc catccgacaa cctttgcgga attgcttcag ctgtctggtc tgtcccacgg
    23341 tactgacgtt tggttgggga atgctcagga tctgattaag caaggaatag cggacctatc
    23401 gactgttatc ggttgtcggg acgacatcat ggtttacctc atgcatgcgg gtctggaacc
    23461 taagatggct tttaccatta tggaacgggt acgtaagggt ttgtggctaa agatttcaga
    23521 agaggagaga aatggctata tcgaagccat gaaggctaat aaggtgccag agtggtatat
    23581 cgaatcctgt gggaaaatta agtacatgtt ccctaaggcc catgcggcag cctacgttat
    23641 gatggccttg cgtgtagctt acttcaaggt tcaccatcct atttattact actgtgctta
    23701 cttctccatt cgtgctaagg cttttgatat caagaccatg ggtgcgggct tggaggccat
    23761 caagcgcaga atggaagaaa tctctgaaaa acggaagaac aatgaagcct ctaatgtgga
    23821 aatcgatctc tatacaactc ttgagattgt caatgagatg tgggaacgag gtttcaagtt
    23881 tggtaaatta gatctctact gtagtcaggc gacagagttc ctcatcgacg gggataccct
    23941 tatcccacca tttgtagcaa tggatggtct gggagagaac gttgccaagc aactggtgcg
    24001 ggcgcgtgaa gagggagaat tcctctctaa aacagaacta cgcaagcgtg gtggactctc
    24061 atcaaccttg gttgaaaaga tggatgagat gggtattctt ggaaatatgc cagaggataa
    24121 ccagttgagt ttgtttgatg agttgtttta aaaaattgct taataatcta ttaaaagagg
    24181 ctaacgtata tccaatagat ttacattagc tttctttttt gttaaaatag tctatggaaa
    24241 gagggtgaga gtatgtcaaa gatgagtata agcatccgtc tggatagtga ggttaaggag
    24301 caggcccaac aggtgtttag taatctggga atggatatga caacagctat taatattttc
    24361 cttcgtcagg caattcaata tcagggatta ccttttgatg ttagactaga cgaaaatcgg
    24421 aagttgctcc aagtgttaac ggatttagac caaaatcgta atatgagcca gtcttttgaa
    24481 tcagtctcag atttgatgga ggacttacgt gcttaagatt cgctatcata aacagtttaa
    24541 aaaagatttt aagttgacta tgaagcgtgg tttgaaggca gaattattag aagaagtttt
    24601 gaattttctg gttcaagaaa aagaacatcc taccagatat cgtgatcatt cattgacggc
    24661 atccaagcat tttcaaggag ttcgtgaatg ccatacccag ccagattggc ttttggttta
    24721 taaagtagac aagtcggaat tgattttaaa tttgctgagg acaggcagtc acagtgattt
    24781 attttaatct attttaaggg ggttctcatg aaactaagaa tatttgcgga agataagccg
    24841 gctaagaagg tatttgaata tcaattagaa cttgctgatc gtacaattct tctatcaaca
    24901 gcactcttgt caggtgctat tgctttagcg ggattattct ctgctttgaa agaaaaataa
    24961 aaatagaaaa gagaaaatta catggtttta ccaaatttta aagaaaatct agaaaaatat
    25021 gcgaaattgt tggttgcgaa cggaattaac gtgcaacctg gtcacacttt ggctctctct
    25081 attgatgtgg agcaacgtga attggcacat ctaatcgtga aagaagctta tgccttgggt
    25141 gcgcatgagg tcatcgttca gtggacagat gatgtgatta accgtgagaa atttctccat
    25201 gccccgatgg agcgtttgga caatgtgcca gaatacaaga ttgctgagat gaactatctc
    25261 ttggagaata aggctagccg tcttggagtt cgttcatctg atccaggtgc cttgaacgga
    25321 gtggacgctg acaagctttc agcttctgct aaagctatgg gacttgccat gaagcctatg
    25381 cgtatcgcaa ctcaatctaa caaggttagc tggactgtag cagctgcagc aggacttgag
    25441 tgggctaaga aagtcttccc aaatgctgcg agcgacgaag aagcagttga tttcctttgg
    25501 gaccaaattt tcaaaacttg ccgtgtctac gaagcagatc ctgttaaggc ctgggaagag
    25561 catgcagcta tcttgaagag caaggccgat atgcttaata aggagcaatt ttcagccctt
    25621 cactacacag cgccaggaac agatttaaca cttggtttgc caaagaacca cgtttgggaa
    25681 tcagctggtg ctgtcaatgc acagggcgaa ggattcttgc caaatatgcc gacagaagag
    25741 gtcttcacag cgcctgactt ccgtcgtgca gatggttatg tcacttctac aaaaccgctt
    25801 agctacaacg gaaatatcat cgaaggtatt aaggtaacct ttaaggatgg acaaatcgta
    25861 gatatcactg ctgagaaggg tgatcaggtt atgaaagacc ttgtctttga aaatgcgggt
    25921 gcgcgtgcct tgggtgaatg tgccttggta ccagatccaa gtccaatttc tcagtcaggc
    25981 attaccttct ttaacaccct tttcgatgaa aatgcgtcaa accacttggc tatcggtgca
    26041 gcctatgcga ctagcgttgt tgatggagcg gagatgagcg aagaggagct tgaagctgca
    26101 gggcttaacc gttcagatgt tcacgtagac tttatgattg gttctaacca aatggatatc
    26161 gatggtattc gtgaggatgg aacgcgagta cctcttttcc gtaatgggaa ttgggcaaat
    26221 tagcaaaaat atcccaaaag caaattgaat tgtaagtatg cttttgggat atttatttat
    26281 aagattttat tagattttga acgattacat ttccaacaga gagtttgaag attgtcaggt
    26341 gtggaaagtc ctccttttga tacagggaca atatggtcta tctcaagtaa caggagagat
    26401 tgttcagctg tagaggcagc acagatttga caagtatagt ggtctctttc ttttatttga
    26461 gttcgaagtt tgtttgtcat cagtgatcgt tgagcttgag cagtttgttt tgattttatt
    26521 ttctttgcaa tatactctgc tgttgcttca acagtttcac cgttaaacag aattgtcgtt
    26581 ttctgagaac tattgcctcc tgcactcacg tattcaaaaa tataagaagt gtaatcaacc
    26641 tttatgtctg gtaggtggat atctaactct ttcattaaat ctttagaaaa gtattttaaa
    26701 ataaattttg gaggattaaa gtcggttttt atttgtttct ctcgttgata aagattatca
    26761 attgtgtttt ccattcgaga gatattctct ccgatttctt caagctgttt caagctttct
    26821 tcggttgcag ttattccgaa atacttacag agataatgta taggttcttc agatgcacgt
    26881 cgcacaactt gtagggaagt tgaataaacg ttactttgat ttaaagtttt cttatgttta
    26941 tctcgtttat agtcatgttg gctagtattt tcaaagtgag ctaaatgtgc atgtttccca
    27001 gtaatatcct ttacaataaa ttgattttta tttgggatat cttttacata ttctgaaa
//
LOCUS       DAVMAH010000032        25148 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVMAH010000032 DAVMAH010000000
VERSION     DAVMAH010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25148
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.032"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(7..237)
                     /gene="blpU"
                     /locus_tag="VYO94_001261"
     CDS             complement(7..237)
                     /gene="blpU"
                     /locus_tag="VYO94_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV1759899.1"
                     /translation="MNTKMMSQFSVMDNEMLARVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            518..2671
                     /gene="blpA"
                     /locus_tag="VYO94_001262"
     CDS             518..2671
                     /gene="blpA"
                     /locus_tag="VYO94_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HEV1759900.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQAPENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILKACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2682..4043
                     /locus_tag="VYO94_001263"
     CDS             2682..4043
                     /locus_tag="VYO94_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV1759901.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEITPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTSL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDTIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLGNNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            4100..4255
                     /gene="blpC"
                     /locus_tag="VYO94_001264"
     CDS             4100..4255
                     /gene="blpC"
                     /locus_tag="VYO94_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV1759902.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(4300..5640)
                     /locus_tag="VYO94_001265"
     CDS             complement(4300..5640)
                     /locus_tag="VYO94_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1759903.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDIERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(5654..6391)
                     /locus_tag="VYO94_001266"
     CDS             complement(5654..6391)
                     /locus_tag="VYO94_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1759904.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(6396..6734)
                     /locus_tag="VYO94_001267"
     CDS             complement(6396..6734)
                     /locus_tag="VYO94_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1759905.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKQGE"
     gene            7011..7340
                     /locus_tag="VYO94_001268"
     CDS             7011..7340
                     /locus_tag="VYO94_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1759906.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7508..8557)
                     /locus_tag="VYO94_001269"
     CDS             complement(7508..8557)
                     /locus_tag="VYO94_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1759907.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFAISLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8554..9285)
                     /locus_tag="VYO94_001270"
     CDS             complement(8554..9285)
                     /locus_tag="VYO94_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759908.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9353..9763
                     /locus_tag="VYO94_001271"
     CDS             9353..9763
                     /locus_tag="VYO94_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1759909.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9773..10060
                     /locus_tag="VYO94_001272"
     CDS             9773..10060
                     /locus_tag="VYO94_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759910.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(10738..11874)
                     /gene="dnaJ"
                     /locus_tag="VYO94_001273"
     CDS             complement(10738..11874)
                     /gene="dnaJ"
                     /locus_tag="VYO94_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV1759911.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12218..12622)
                     /locus_tag="VYO94_001274"
     CDS             complement(12218..12622)
                     /locus_tag="VYO94_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV1759912.1"
                     /translation="MDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARYREI
                     ILAEHDSCIKNDEAVRNFVTSVLLSAFVSALVSAMISLEIQTYKFVIPFIIGMIWTVV
                     VFLMINWNYIANTKKRQKYINISVLIGYLKSK"
     gene            complement(12633..14456)
                     /gene="dnaK"
                     /locus_tag="VYO94_001275"
     CDS             complement(12633..14456)
                     /gene="dnaK"
                     /locus_tag="VYO94_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV1759913.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14936..15460)
                     /gene="grpE"
                     /locus_tag="VYO94_001276"
     CDS             complement(14936..15460)
                     /gene="grpE"
                     /locus_tag="VYO94_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV1759914.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15487..16521)
                     /gene="hrcA"
                     /locus_tag="VYO94_001277"
     CDS             complement(15487..16521)
                     /gene="hrcA"
                     /locus_tag="VYO94_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV1759915.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVHLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16685..17122)
                     /locus_tag="VYO94_001278"
     CDS             complement(16685..17122)
                     /locus_tag="VYO94_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV1759916.1"
                     /translation="MHLKGWRYRTSRFGLFYFEQGQPDDVIYRIYDSRFLKKYKHELQ
                     DFRDRGWELIGAGSCSILRKSSSDLLPEVQVYMSKGLKWEVMRSRLRSCTATFLGGLV
                     VCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFRLKRKYRVDE"
     gene            17801..20134
                     /locus_tag="VYO94_001279"
     CDS             17801..20134
                     /locus_tag="VYO94_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1759917.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKEDSNWRKVIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVGEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20147..21610
                     /locus_tag="VYO94_001280"
     CDS             20147..21610
                     /locus_tag="VYO94_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1759918.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPKELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21610..23178
                     /locus_tag="VYO94_001281"
     CDS             21610..23178
                     /locus_tag="VYO94_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1759919.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRISTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLAR
                     FIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYAWAVADSHVTVIRV
                     LSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIV
                     DKIEQFFAHIDALI"
     gene            23235..24032
                     /gene="psrA"
                     /locus_tag="VYO94_001282"
     CDS             23235..24032
                     /gene="psrA"
                     /locus_tag="VYO94_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV1759920.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLTFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            24043..24651
                     /locus_tag="VYO94_001283"
     CDS             24043..24651
                     /locus_tag="VYO94_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1759921.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETTSYPIYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(24599..25144)
                     /locus_tag="VYO94_001284"
     CDS             complement(24599..25144)
                     /locus_tag="VYO94_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1759922.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT         8092 a         4964 c         4592 g         7500 t
ORIGIN      
        1 ccataattac caccaacatg ttgctgcata ggctacacct ccaagtatag ctccacccgc
       61 agcaccagtt gctgcacctt gccatgttcc tgttttaatg cctagttgaa gacctcttgc
      121 tgctcctcct ccaacacctg ctttggcaaa atctccccaa ttgcatccgc caccttcaac
      181 acgagcaagc atttcattat ccataacaga aaattgtgac atcatttttg tattcatgac
      241 aaatactcct tttttatttt taatttttgt cttgttgcaa ctttgacaag tttagtatat
      301 cattattttt taattttttt catccaaatc ttgaattggc atcgaaacgt cttgaattag
      361 cttttttatt tcaagccacc tctaaatgtt taaaaaaaat aatttctaat cactttttta
      421 ccattcagga agttttaatg actattcaag atttcataaa atatgaactt agttttatgg
      481 cataatatac ctatccacta tatgaaagga attgccaatg acttcttata aacgtacatt
      541 tgttcctcaa atagatgcga gagactgtgg tgtcgctgcc ttagcctcga ttgctaaatt
      601 ctatggttca gatttttctc tagctcactt gagagaactt gcaaagacca ataaagaagg
      661 gacgactgct cttggcattg taaaagccgc tgatgaaatg ggctttgaaa caaggcctgt
      721 tcaagcagat aaaacgctct ttgacatgag tgatgtcccc tatccattta tcgttcacgt
      781 taacaaagaa ggaaaactcc aacattacta tgttgtctat caaacaaaga aagactatct
      841 gattattggt gatcctgacc cttctgtaaa aatcactaaa atgtcaaaag aacgcttttt
      901 ctctgaatgg actggagtag ctatttttct agctcccaaa cccagctatc aaccccataa
      961 agataaaaag aatggtctac taagcttcct tcctctgatt ttcaaacaaa aatctctcat
     1021 tgcttacatt gttctctcaa gcttattggt cactattatc aatatcggtg gttcttacta
     1081 tctccaagga atcttggatg aatacattcc aaatcagatg aaatcaactt taggaatcat
     1141 ctcagttggt ctggttatca cctatatcct ccaacaagtc atgagcttct ccagagatta
     1201 tctcctaacc gttctgagcc agagattaag cattgatgtg attttatcct atattcgcca
     1261 tatttttgaa cttcccatgt ctttctttgc gacacgtcgt acaggagaaa tcatttcacg
     1321 gttcacagat gctaactcta ttatagatgc cttggcttct accattcttt ctctttttct
     1381 ggatgtttct attctgattc ttgtaggggg cgtcttactg gcacaaaacc ctaatctctt
     1441 cctcctttct cttctttcca ttcctatata catgttcatc atcttttctt ttatgaaacc
     1501 ttttgaaaaa atgaaccatg atgtcatgca aagtaattct atggttagct ctgccattat
     1561 cgaagatatc aacgggattg aaactataaa gtcgctcacg agtgaagaaa atcgctatca
     1621 aaatatagac agcgaatttg tagattattt ggaaaaatcc tttaagctca gtaaatattc
     1681 tattttacaa acgagtttaa agcagggaac aaaattagtt ctgaatatcc ttatcctatg
     1741 gtttggcgct caattagtca tgtcgagtaa aatttctatc ggtcagctga ttacctttaa
     1801 cacacttttt tcttacttta caactcctat ggaaaatatt atcaacctcc aaaccaaact
     1861 ccaatctgcg aaggttgcta ataaccgttt gaacgaagtc tatctagtcg agtctgagtt
     1921 ccaagcccca gaaaaccctg ttcattcaca ttttttgatg ggcgatattg aatttgatga
     1981 cctttcttat aagtatggtt ttggacgaga taccttaaca gatattaatc tcacgattaa
     2041 acaaggagat aaggttagcc tagttggagt tagtggttct ggtaaaacaa ctttagccaa
     2101 aatgattgtc aatttctttg aaccctacaa agggcatatt tccatcaatc atcaggatat
     2161 taaaaacatt gataaaaaag tcttgcgccg tcatattaat tacctacccc aacaagccta
     2221 tatctttaat ggctctattt tggaaaactt aaccttgggc ggtaatcata tgattagcca
     2281 agaagatatt ctaaaagctt gtgaattagc tgaaattcgt caagacattg aaagaatgcc
     2341 tatgggctat caaactcagc tctctgatgg agctggtcta tcaggaggac aaaagcaacg
     2401 aatcgctctc gctcgtgctc ttttaactaa agctcctgtt ttaatactag atgaagctac
     2461 tagcggtctt gatgtcttga ctgagaaaaa ggttatagat aatcttatat ccctaactga
     2521 taaaaccatt ctctttgtag cccatcgtct cagtatagcc gaacgaacta accgtgtcat
     2581 tgttcttgac caggggaaaa tcattgaagt tggtagtcac caagagttaa tgcaggcgca
     2641 aggtttctac catcatctat tcaataaata aggagaatgt catgaatcct aatcttttta
     2701 gaagcgtcga gttttatcag agacgttacc ataactatgc gacagtatta atcatacctc
     2761 tttcattatt atttactttc atcttgattt tctcccttgt tgccacaaaa gaaattactg
     2821 ttacttccca aggggaaatc acccctacaa gtgtcattgc atctattcag tcgaccagtg
     2881 ataatcctat ccttgctaat catttagtgg caaatcaagt agttgagaaa ggtgacttac
     2941 tcatcaaata ctctgaaaca atggaagaga gtcagaaaac ttccttagaa actcaattac
     3001 aaagacttga gaagcaaaaa gaaggacttg gaatcttgaa acaaagctta gaaaaagcga
     3061 ctgatctttt ttctagcgag gatgagtttg gctaccataa tacttttatg aattttacta
     3121 aacaatccca tgatattgaa ctgggtatct caaagactaa cactgaagtt tcaaatcaag
     3181 ctaatcttac caatagcagt tcatcagcca tcgaacaaga aattacaaaa gttcaacaac
     3241 aaattggaga atatcaagag ctgagagata ctatcgtaaa taaaagagct cgcttaccaa
     3301 ctggcaatcc gcaccagtca attttaaatc gttatcttat agcctctcaa gaacaaacac
     3361 aaggaacggc agaggagcca tttttatctc aaattaatca aagtattgca ggtctggaat
     3421 catctatcgc aagcctcaaa attcagcaag ctggtatcgg aagtgtagca acttatgata
     3481 atagtttagc aaccaaaatt gaagtactcc gcactcagtt tttacaaaca gcctcacagc
     3541 aacaactaac cgtggagaat caattaacag aattaaaagt acaactagat caagcaacgc
     3601 agcgcttagg aaacaatacc ttaaccgctc caagtaaagg tatcgttcat ctgaacagcg
     3661 aatttgaagg taaaaataga attccaactg gtacagaaat tgctcaaata ttccctgtca
     3721 tcacagatac aagagaagta ctaatcactt actacgtatc atctgactat ctccccttac
     3781 tagataaagg acaaactgta agattaaaac tggagaagat tggaaatcac ggcaccacca
     3841 tcatcggcca acttcagagt attgatcaaa ctcctaccag aacagagcaa ggcaatctct
     3901 ttaaattaac cgctcttgca aaactatcta atgaggatag taaactcatc caatatggct
     3961 tacaaggtcg cgtcactagt gtaactgcaa agaaaacata ttttgattat ttcaaagata
     4021 aaattttaac ccattctgat taattttcag ataacactct ataactattt attatcttat
     4081 caaaaaggag aatcataaca tggataagaa acaaaaccta acttcatttc aagaactaac
     4141 aactaccgaa ctcaaccaaa ttacaggtgg aggactgtgg gaagatatct tatacagcct
     4201 taatataatt aagcataaca atacgaaagg acttcatcat ccaatacaac tataaaaaat
     4261 aagaccgagt aacaagaact ctcggtctta tttttttcat cattctgtag gtatcatagt
     4321 aagcacctga cgaaagactt gatcttgaca ggtagtattt aaactggcat tgggataact
     4381 ttccacaatc ttcataacgg tatagagacc gacacctctc tcctcccctt tagaactaac
     4441 tccaaaggag aagatttcag aaatatcgat gccctcttct ttgatggaat tttcgatgat
     4501 gaaggtctcc tgtgctccac tttttaaaaa ggcaattgaa acatgaggtt gaccggcctc
     4561 tgcactcgct tcaatagcat tgtcacaaag gatagacaca atggttagaa aatcaagcag
     4621 tctcatcccc tcaacctgaa tctcttcagg aacttcgaca ttaaagacaa tgtccttttc
     4681 tctagctttt ataaattttc cagctaggag acttttgagg gcacgatccc gaacattcac
     4741 caatcggcca aggtcatatt tattgtcctg caatttttta ctagaatcct ttaagaccaa
     4801 gtcatagacc tcttttatct gctccatatc ctcctcttca atacccagac gtaaacttgt
     4861 caagaggttg gtgtagtcat ggcgaaaact ccttacttcc ttgtaaagtt cctctatatg
     4921 ccgactatag cgttctatat ctctatagcg caagacctgc tcttggtcca gtctatcatg
     4981 gagtttgtcc ttcaaatagg tatccaattt cttgataacc cccataaaaa ataggaggta
     5041 gaacactagg atgagatggc gaacagtcgt tgattgaata ccttgctcat attcaaagta
     5101 agacagactt tgtatcacca aatagtaagc ccccattatc cagttaatct tagtcaggga
     5161 cttttgaaaa cctgtatcta gaatctccct tctcaaacta gtaaaatcat agtccaacca
     5221 tttcaaaaag gctagagaaa tgaagaaatt gaaaattatt atacataacc cagtgaatga
     5281 gtagccatca tatacttgcc cttgtcccaa aaatggaagc acaaaatagg agactcctct
     5341 ataaaagaga ttcaccaata tcattggaaa gagaccataa aagaaaagga gttttttagg
     5401 aagccctctt aacaataaga aagacaagcc tatgccgtac aagggttcca taaaataaga
     5461 taggtaaaca tttcctacta tatagctaat cattacaaaa acaacggcca acagtatctt
     5521 aaaaagaaag gccttaaaaa tcctctcaaa agtgagacta attccatcta ccttaaagaa
     5581 tatgacaatt tttaatccgt gagtaacaag tgtatacaac aatatccaag caacattcat
     5641 aaactctcct agctcagtgt aagttattaa tagcctcaga cacttccctg accttataac
     5701 gcgcgattag acaacttcca ccattgggaa agaaaagcag tttttctttc ttatctaaat
     5761 gcaccacatt ggcaggattg atgagaaaag agcgatggca ctgcaagaga cgaggctcct
     5821 gcttgagaac ctcctctaga ctcgctgtaa attccagcct gtctgtcttg gtatagagaa
     5881 taacacgatg gggtcttgtg gacgtttcga gatagtaaac ctctttaaaa ggatactgaa
     5941 attgggcaaa ttttgattta aagtaaaagc aatcttccgc cagactttta ctatcttgac
     6001 tattggcata gaggagagct gtctcgattc gagattcaaa ctcctctgcc gaaagggcct
     6061 tatcaatata gtccagagca gacacttggt agcgaaagga caggggcata aactccgagt
     6121 gagtcgtcac aaagacaatc agggcatagg ggtcttgttc ccgaatcttt ctagccactt
     6181 ccagcccctt catctcctca tttcgaatct caatatccaa aaagaatagc tgatgggccc
     6241 ccttctcatg cacctctgcc agcagttggt ctggcttgcc aaatacctca aaagagctgg
     6301 gagtgatatg atgttccttc aagagtttct caatcgtcgt ttcaatccta gtctgttggg
     6361 aaaaatcatc ctctaaaaca aatattctca tctttttact ctccttgttt taaccatttt
     6421 tgacgaattt ctctatagcg acgtctggca tacttgacag cgtattgacc ttcttctccg
     6481 agaaaaagga ttctttcttg aaaatcaatc gattttaatt tatcaagatt aaccaaacaa
     6541 tttcgatgac atctcatcaa ggtttcccca tattggttct caagattact taaattttga
     6601 agcatattaa aactagcttc ttctgtaaca atctgtacgg tatgggcttt agttggatgt
     6661 gtttggatat agtagatatc gtcgacgttt actttataga ctgttttctg cgtctgaata
     6721 atcatatgtt tcattggatt ctcctcctaa gaaaagaata acagaaaagt tctagcccaa
     6781 gcccacccaa tcctaaacag tctttgaaag ctcctaaaag gattattttt ctacaacatc
     6841 atgatgagct tacaactatt ttatcataaa attcactcag cgcaattcaa gacatttcaa
     6901 tgacaattaa agatttgaat aaaaaaaaag aattaaaaat gataaactaa cagtatcaaa
     6961 acacagttgc cagaagtaag actggcaccc agattaaagg aggcattccc atgacagata
     7021 cagaccccat caaaagagct catactttga ttactgactt aaacaaagcc taccaagcat
     7081 gcaaacaggc aagcgctgac gacgtccgct ttcaggagca attaaactct attcttggtt
     7141 ttctagccaa ggctgaaaca gtggataatc gattcttgat tgaactagaa aaattttacc
     7201 agacttccag tcttctcatg ggactcagcg ctcttgatcc agatgctcca actcgcgccg
     7261 cttggcgggc ctatgaccgc ttccactttg accaagtcaa gaccaagtta atactcaatg
     7321 aaaatcaaag agcaaactag gaagctagcc gcaagctgta cttgagtacg gtaaggcgac
     7381 gctgacgtgg tttgaagaga ttttcgaaga gtataagtct ctacggacca accattatcc
     7441 tgtagtaaca aaaaagaagc tgagacaaac tgaactcaac ttctttttta gtgtcgtatc
     7501 agcaatgtta gtcctgcatc tgacgtttta cctgataagg caaatacaag actagtaaaa
     7561 ccaaaccagc tcctagtaag gctagaaggg ctagtttttc ttggaaggta atcaacccaa
     7621 caactaattc cacaagtaaa acaaaactgg tcaatcctcg aactacctcc tgtaagcctt
     7681 tttccttttg ccccttgtcc agcggaaaga gttgggtcaa atactggtag tcaaaggcat
     7741 gatagagggc cagcaactgg aagagcaaga ggtagttaaa gagaactacc actgctgtcg
     7801 caatccaagc ttgctcgata aaaacctgcg ccagtacgga aagtaataga agacgaagac
     7861 tgatagcaaa gaggtcgcca tttcgcagat aagaacgcag atagagattt tgccaaatct
     7921 tcccaggcac cttctgaaca gcctttaaga taaagtccag ataggcacga cgcttaacgc
     7981 tgtttgaaat tcccttgacc tgcgtaaaga gggcaaagaa acgaagcaag acttgcttac
     8041 gcttgctttc ttgagaaata acatagtccc agtccagtcc agtttcagta aaaaatttgc
     8101 tggccttttg acgaaagtgg aaatattttc ctacccccaa taaaagcaca tagagcagaa
     8161 aaactggcaa gccataaccc attgctaaaa ataaaggcgc aaataacagc aagaaaaggg
     8221 tctgtacaaa gagccaaaag actagggaaa tgccagtttg acgcttgaga tggagcttga
     8281 tttcctcttc tccaactaag agaaagagct tgtctggagc ctccatatag gtggcaattc
     8341 ctccccaaag taagagtaaa acagacgtaa ttcctacaaa caaaaggata ggccaatgat
     8401 tttcaggaaa atgttgtaag agttgactgt actggtaggc tagaaagccc aacaggacaa
     8461 gcaggaacaa gacaaagtgg tcattgagca catagcgcag ataaccaaga cactccttac
     8521 gaaaggcctg ctttctcttt aaaaacaagt ctttcataga tcctcctctt tggtcagagc
     8581 caagtaaata tcattcaaac tagcctcagg catatcaaag gcttcacgta gttgcaggag
     8641 attgcctttg gcacgcacct ctcccttgtg aagaatgaca aaggcatcac acatcttctc
     8701 cgccgaatcc agcacgtggg tactcatgag aatagacttg cccttttgct tctccacttc
     8761 caaaagctga atcaaatcag aaatagccag cggatcaaga ccaaggaaag gctcatccac
     8821 gatgaaaaga cttggatcca ccacaaaagc acagataatc atgaccttct gcttcatccc
     8881 ttttgaaaaa tgaacaggga accagtctaa tttctggtcc agacggaaca tctttaacaa
     8941 gggctctact cgttcgaaag ccactttttg ctcaataccg taagccatag caaccgtttc
     9001 gatatgctct ctgagggtca attcctcata cagactaggc gtctcaggaa tgtagccaat
     9061 ctgcttgcgg tagctagtcg catctccttg cagagtcagg ccattgatat tgatggagcc
     9121 actataaggt gccaacagac cgataatctc attgatcgtc gttgatttcc cagcaccatt
     9181 gagaccaatc aaaccgacca actgcccact ttcaacagta aaggacacat ctttcaaaac
     9241 aggaacatga acatagccac ctgtcaggtt tttaatttct aacatatttt ctccaaatct
     9301 ggtataatgt agctatatta tatcaaaatt cagtacagta gaggtagatt ttatgtcaga
     9361 ttgcattttt tgtaaaatca tcgcagggga aattcctgct tcgaaagtat atgaagatga
     9421 gcaggtcctt gcctttcttg atatctctca agtaacacta ggacacacct tggtcgtgcc
     9481 aaaagaacac tatcgcaatc ttttggagat ggatgctacg agcgccagcc aactctttgc
     9541 ccaagtacca aaagtagctc aaaaagtcat gaaagtcact aaggctgctg gtatgaatat
     9601 catttccaac tgtgaagaag tcgctggtca aacagttttt catactcacg ttcaccttgt
     9661 gcctcgctac agtgctgacg atgacctcaa gattgatttt atcgcccacg aaccagactt
     9721 tgacaaactt gctcaagtcg ctgaaaccat caaaaacgct taaggagttg ctatgaaatt
     9781 atccaaccta ctgctatttg caggagctgc agccggaagt tatctggtta caaaaaatcg
     9841 ccaaaccatc acagatgaag tcttgaatac cactgaccgc gttcaagcta tcaaggacga
     9901 tgtggatatt atccaaaaca gcctgcaaat cattaaccag caaaaagaac ttatcaagga
     9961 ataccaagaa gacttgactt acaagtttaa ggtcttggaa aaggatatcc agactagact
    10021 agctgtgata aaagaaatgc agggaactga agataagtaa aaagagcccc ccggctcttt
    10081 tttaaaacgt aaacaagtta tagtgaattg aatttagaat agcacaccat agtttctaaa
    10141 gcattgttag agattacttt aaaatcctct tatcaatttg ttcatattct atttcaatct
    10201 attatatata tcccatcaac tatgcatcat aatttaggta actcatactc aataaaaatc
    10261 aaaaagcaaa ctagaaagct aggcacagac tgctcaaaac accgttttaa ggttgtggat
    10321 agaactgacg aagtcagtaa ccatacccat gacaagccga cgctgacgtg gtttgaagaa
    10381 atttttgaag agtatcattc accatttcac aactaaatcg aagactttct gccgtaatga
    10441 aaacacctga aacagcttgg tttcagctgt ccggaaactt taagacttag gttcaaagtt
    10501 taggtatgga acttcgaaga aggtcgctac cgtccgtcat tacttaggaa agtcttaaaa
    10561 aatctataaa gtaaaaagag cccgacagct ctttttgttt atactcaatg aaaatcaaaa
    10621 agcaaactag gaaactagcc acgggctgct caaaacactg ttttgaggtt gtagatacga
    10681 ctcacatata tacggcaagg caacgctgac gtggtttgaa gagattttcg aagagtatta
    10741 ttctccatca aaggcatctt ttatatggtc aaagaagcct tttttctttg gatttacttt
    10801 caagtcacca gcagccgcga attctttcaa ggctactttt tggcggtcgt tcaagcctgt
    10861 cggtgttacg acattaacag taacgtattg gtcaccaact gcaccgccac gaaggctcgg
    10921 tgccccctta ctacgtaggc ggaatttctt accagtctga gttccctctg gaataaccaa
    10981 ttcaacatca ccgtgaacag ttggaatatc tactgtatca ccaagagccg cttggacaaa
    11041 gttgaggttg agattgtaga agatagtcgt tccttcacgt tcaaacttgt cgctagcttc
    11101 tacagaaact actacataca agtccccata aggtccaccg ttaaagcctg cttcgccttg
    11161 accagcgagg cgaatttgtt gacctgtttc cacaccagca gggattttca catgtacgct
    11221 atgagcttgt ttctcatgac ctgttccatg acaggttgta catggatatt tgatttcttt
    11281 tcctcgaccg tgacagacat cacaggttac ttggcgacgc atcataccaa gaggagtctg
    11341 cgtatcgacg ttaatgacac cagcgccatg acagcgtcca caagtgactg gacttgtccc
    11401 tggcttagca ccagagccat tacatgtacg acagccagct tcacgatgat acttaacttc
    11461 cttctcagtt ccgaagatag cttcttcaaa ggtcaaattg acacgatact ggagatcatc
    11521 tccttggcga ggagcgtttg gattgcgcga agaaccgcct ccgccgaaga aacttgagaa
    11581 aatatcctca aaaccaccga agccacctgc cccattgaaa ccaccgaaac caccagctcc
    11641 accaaaacca ccattggcgc ctgcagcacc atactggtca taggcagcac gtttttggtc
    11701 gtcactcaaa gtctcatagg cttcttgaac ttccttgtac ttgtcctcag caccaggctc
    11761 cttgttgata tctgggtgat attttttgga aagcttacga taagcctttt tgatttcgtc
    11821 tgccgaagcg tttttggata cccccagacg atcataaaat tcagtattgt tcataattca
    11881 agatacaaag ggcgtcaaac ggacacagcc atctaggagt tttgacgacg gacgcttacg
    11941 tcctagaaaa aactatcttt ttggcacagt ccgtagcccg tgttcagtta cgaacaccct
    12001 tattcctttc tattaatgtt ctgaatcgaa ccaccattta ggtcgggttc aattcctttc
    12061 ttttatattt agtaagaaat tctgaaaccc gtgttcagtt acgaacactc tttgttccct
    12121 tctattgatg agacaaaacc caaacaaata agattccgtc cctttttatc gaaaaacaga
    12181 ggctgggttg caacctctgc aaataagtaa attaacttta ttttgatttt aaatatccta
    12241 taagtacaga aatatttata tatttttgtc tcttcttagt atttgctata taattccaat
    12301 tgatcataag aaatacaact actgtccaaa tcataccaat tatgaacggt attacaaatt
    12361 tatatgtttg tatttctaat gatatcatag ctgataccag cgccgataca aatgcagaca
    12421 acaatactga ggtaacaaaa ttccttaccg cttcatcatt tttgatacaa ctatcatgtt
    12481 cagctaatat aatttctcta tatctagcta aatattctat tggaatatta tcaataaaat
    12541 cttttgatgt tctatagtta tcagcttgat tacaaaaatc attataaact tttcgtgtat
    12601 tttttagata ctcttcatcc aatacactcg tcttactttt ccgtaaactc tccgtctacg
    12661 acgtcatcgc ctgcgtttcc tgttgcttgt gcgccttctg ctccttcttg agcttgttgc
    12721 gctgctgcgg cttgttcgta gagtttcaca gcaaggcctt gagctttttc gttcaacgct
    12781 tcaagtttcg ctttcatgtc gtccaagttg ttgtcttctt gagctttctt aaggtcatca
    12841 agggcagctt gggcagcgtc acgttctgcg tcgaagcctt taccttcagt ttccttgatt
    12901 gtcttttcag tcgcaaagat tgcttggtct acttcattac gaaggtctac ttcttcttta
    12961 cgtttcttat cagcttcagc gtttgcttct gcatctttca tcatgcggtc gatttcttcg
    13021 tcagtcaaac ctgagttcga ttggatgaca atagtttgtt ctttttgagt tccaaggtct
    13081 ttggccttaa cagacacgat accgttcttg tcgatgtcaa atgttacttc gatttgagga
    13141 attccacgag gtgcagctgg gatatcagtc aattggaagc gtccaagagt cttgttatct
    13201 gctgccattg ggcgttcacc ttgaagaacg tggatatcaa cggctggttg gttgtctgct
    13261 gctgttgaga agacttgtga tttagatgtt gggattgtag tgttgcgatc gataagtttt
    13321 gtaaatactc cacccattgt ttcgatacca agtgacaatg gcgttacatc aagaaggaca
    13381 acgtccttga catcaccagt aatcacacca ccttggatag ccgcacccat agcaactact
    13441 tcatcagggt ttactgattt gtttggttct ttaccagttt cagctttaac agcttcaaca
    13501 acggcaggga tacgagttga accaccaaca aggataactt cgtcgatttc tgacaagctc
    13561 aaacctgcat ctgaaagggc ttgacgaact ggaacttttg tacgttcaac aaggtcacga
    13621 gtcaaatcgt caaatttcgc acgagtcaaa gtcatttcca agtgaagagg tccagcctca
    13681 cctgcagtga taaatggcaa gctgatttgt gttgaagtta caccagaaag gtctttcttc
    13741 gctttttcag ccgcatcttt caaacgttgc attgccatct tgtcagtaga caagtcgata
    13801 ccgttttctt tcttgaattc tgctaccaag tggtcaatga ttttttggtc aaagtcgtca
    13861 ccaccaagtt tgttgtcccc tgcagttgac aatacgtcga agacaccgtc acccaattca
    13921 aggatagaga cgtcgaatgt accaccacca aggtcaaata ccaagatttt ttcttctttg
    13981 tcagtcttgt ccaaaccata agcaagagct gctgcagttg gttcgttaac aatacgttct
    14041 acttcaagac cagcaatttt accagcgtct tttgttgctt gacgttgagc gtcgttgaag
    14101 taagccggaa ctgtgataac agctttggtt actttctcac caaggtagtc ttcagcgtag
    14161 cctttcaagt attgaaggat catagctgag atttcttgtg gagtgtattc ttttccattt
    14221 gcagaaactt tttcagaagt tcccatctta gatttgatag agataactgt atctgggttt
    14281 gtaactgctt gacgttttgc agcatcacca acgatgattt ctccgttttt gaatgagact
    14341 acagatggag ttgtgcggtt tccttctggg tttgcgatga ttttgctttc agttccttca
    14401 agaactgcaa ctgctgagtt tgttgtacct aagtcaatac cgataatttt agacatgtgt
    14461 ttttctcctt gttagttaat tttctatttt tctttttgat actcttctta agtggcgacg
    14521 ccgtcagagc ttgacttcgt cagtctcttt gactaaactt tgagcctaag gtctcaaaat
    14581 ttgcgcaaat agcgccacgg cgaagagtat cgtctttggt tcgcttcgct cactattaca
    14641 aagcaaaaca tattttatct ttcttcatag tttattgtcg tttcggacaa gttttctatt
    14701 atgtaaattg cgacacgagg agtcgaaatc gattttattt cgacgacgag ttagtaagga
    14761 agctaggcaa acgccatagc aattgccgtt ttctgacgag ttgctttagc taccgtcaga
    14821 attgccgaat cgaacacgcc ctaagctctg agtaaaaaag atagattttc ttgtgttcat
    14881 cgaacacttc gttaatctcc tatttttact gcgagctttt tacgggcttt gtatcttagt
    14941 tatacaccac taccattgct gggcgtagga tgcggtcatg gagtttgtag cctttttgaa
    15001 agacttgggc gatggtatct actgggtgtt catcgtctgc tgggagagtt tggatggcca
    15061 tatggtagtt atggtcaaat tcgccatctg ctgcgatttc ttcaattcct tcttctttca
    15121 aagcgtgaat caagctttct tgcaccatcc ccaagccctt cttcacatca tctgtcaaac
    15181 cttcaactgc aagtgcacgc tcaaggttgt caagagatgg taagattgct tttgccaagt
    15241 cctggctacg ataacgttgc aagttttgac gttcttcatt ggcacggcgt tggatatttt
    15301 gcatttctgc atgagcgcga agatatttgt tttcgaactc atctgcacgt tcatttgcca
    15361 agtccaactc agacttttca ggagttgttt cttcagctgt ttccacaact tcctcttctt
    15421 gaacttcttc tacttcttca ttttttatat cttgggccat gttcgcctcc tttaatgatt
    15481 tcaatcttaa tgtacttcgt aatgattact gctgaggtag cggtaaaaat ctgtcaactt
    15541 catggtcaaa acacggttga ccacattgac ttgattgatt agctgttggt aatccagatt
    15601 aactggaccg ataatggcta gaattccaac tccccgataa ggaatgagga acttactact
    15661 aattaccgct aggtcagcta aacaagactc ttgaccgtct gcaacacgaa cattttgcat
    15721 ctgatcctca cgcaacccct cacgaatctc caaggccacc ttttgcggtt ggtcaaagaa
    15781 ctgataggct gctagattgg caaaattcaa gagatggacc ttgcccgcca tcacaatgtt
    15841 ttcgttgaac atttccttaa agatgtgttc aaagagatcg atgacattat ccgttgttgt
    15901 aaagtaacgc tggataatct gcggaatctc cgtccgaatc ttgtagtgaa tatctaaaac
    15961 ggtgtgaccg aggaaacgtt cctgaatgat gctcttcagt ttcagcaaat cctcctgcaa
    16021 gaagttcctt ggaatcagaa actgactagt aaccgttcgc gactcgtcta gggtaaatac
    16081 cgccaaggct gtatgttgcc ccaaaacaac gatatcaaag gctgtcaaac gttgcctgct
    16141 cggctcaaca tccagtgcca ctaccgtaca gccactcagg tctgttaaca agttagcagc
    16201 ctcttgcaga atatcctcca atttgaagaa ttcctgatca aaggctttga caatctcata
    16261 tacctcattt tcagccagtc ggtcaaaatc cagtgagtgt ttcacatagt actgaaaacc
    16321 agcaacactt ggcatccgac cgcttgaagt atgagccttc tcaagcaacc cttgtttttc
    16381 tagttccgcc atgtcattac gaatggttgc actgctagag ttaatagact cttgcaaggc
    16441 ttttgatccg acaggttcgt gcgttttggt aaagatgtca ataatcagat ttaaaatatc
    16501 ctgctgacgc tctgtaacca tctcatcact cctctctgtc tgatcaatta gcactcaatg
    16561 catccaagtg ctaacttatg attctattat acacccttag aagagaatgt caagacaaaa
    16621 actcaaaaaa ttagcactct tttataaaga gtgctaaaaa tcaatctgaa gacctagaac
    16681 cttgctattc atctactcgg tatttccttt ttagtctgaa ataaccatga attagataag
    16741 aaatcagaaa agcatataaa acaaaaataa gaaagaaaga catagaaaga tcctctctaa
    16801 acaaactcat acaaacaaca agaccaccta agaaagtagc tgtacaggaa cgaagtctag
    16861 atcgcataac ttcccatttg agccccttac tcatatagac ttgaacctct ggaagtaaat
    16921 cagaagacga tttacgaaga atcgaacaag aacctgctcc tatcaattcc caacctctat
    16981 ctctaaaatc ttgcagttca tgcttatact ttttaagaaa tctagaatca tagatacggt
    17041 agatgacatc gtctggttga ccttgctcaa aatagaacaa accaaaacga ctcgttctat
    17101 acctccaacc tttcaaatgc atctcatgta aatattcttc ttacttgtcc aaatcaggaa
    17161 tagtgaaaat ccgaaattct actctgctat tcattgtctt accccaaaat tagaaaacat
    17221 gcctggcgtt atttattaga taattctttc cacttttgac tcaatctcca aaaaatataa
    17281 gaaatctgaa tcgcaaaaac tattaataaa acccaatcta ttatgaaaat caaaaatact
    17341 ccccaactga aagaactacc tccagtgaca aactttgaga aaaacggtag tagagctaaa
    17401 aagagaagca aaataggaag catccgcatt gttaaaatcc gtttggcata aaaaatcttt
    17461 atttaaacga aaatattatg gcaaaattta cgccagtttt tgaacggctg atgtagatat
    17521 tttatacttt caaaatgttt aaatgtgatt atttattttt gaaaaatagc tcaccagccc
    17581 gactgaaagt gcttatagaa tgataataag tcgcctgccg aaaacagcgg aaaatagcgg
    17641 tgttatgcgg agataatctg acgcgatgcg aaagtatatt gcatacttat tttcaacaat
    17701 ttagcagagt atttttataa gtgtgatata atagaagtat aatttgttct gatagtttat
    17761 tttatggaga agtagatttt tagaatgcgg agggttcaat atggttgagt ttataaagtc
    17821 taagaaagaa atgagtgagg aggatattaa agcaaatttc atcactcctg ctattgtatc
    17881 caaaggatgg aaaaatggtg agcatatcgc ttacgaagaa tacttcactg atggtcgaat
    17941 tgaggttaga ggagataagg ctcgtcgtaa agaaggaaaa aaatcagact attcactgta
    18001 ttaccaattt ggaactcgaa ttgcaattgt tgaggcaaag gataataaac acagcgttcg
    18061 agcaggatta caacaagcta ttgaatatgg agagatttta gatgttccat ttgtttattc
    18121 ttcgaatggt gatggcttta ttgaacacga ccgtatcacg agagaagaac gtgagctgga
    18181 gttagacgaa ttccctactc gtgaagaatt attttctcgt atgacgaagg aaaaaggatt
    18241 gacgtacgaa attacagaag ctatctcaac tccatactat acagacgcct tctcaatgaa
    18301 aacgccacgc tattatcagc aaatagctat caaccgtact attgaaacag ttgccagagg
    18361 acaaaaacga gtaatgtttg tgatggcaac aggaacgggg aaaacgttca tggcttttca
    18421 aattattcat cgccttcgaa aagctggttt ggctaaacga gttttattct tagcagatag
    18481 aaacatctta gtagaccaaa cgatggctga agactttagg ccattcgaaa aggtaatgac
    18541 gaaaattaca ccaaaacttt tgactgctcc tgaaaaatta aattcttttg aaatttatct
    18601 agggctttat cagcaactaa ctggtgaaga tggaactgaa acacattatc aaaaatttga
    18661 caaagacttc tttgatttaa tcgtaattga tgaagcgcac cgtggttcag ctaaggaaga
    18721 cagtaactgg cgtaaggtga ttgattattt cagttctgcg acacagattg ggatgaccgc
    18781 tactcctaaa gaaaccaaga atgcttccaa tacggaatac tttggtgagc caatctatac
    18841 ttatagttta aaacagggaa tcgaggatgg ttttttggct ccatatcgtg ttatgagggt
    18901 taatttagat gtggatgtgg atggttatcg tccagaaact ggaaaagttg atgctaacgg
    18961 acaattaata gaagataggt actacggcag gaaagatttt gataaaacca ttgtcattga
    19021 tgatagaacg caaagagttg ccaagtttgt ttctgattat atgaagcaaa acaatgcacg
    19081 atttgataaa acaattgttt tttgtgttga tattgaccat gccgagcgaa tgcgtgctgc
    19141 acttgtaaaa gagaatctag acttagtcca agaagactat cgttatgtca tgcaagtaac
    19201 tggtgacaac gctgaaggaa aagctcaact ggataacttt atggatgtca attctaattt
    19261 tcccgctatt gtaacaacgt ctaaattatt aacgacagga gttaatgcta aaacatgtcg
    19321 tttgattgtt ttagactcta atatccaatc catgactgaa tttaaacaaa ttattggtcg
    19381 tggcacacgt ctttatcctc aaaaggggaa agaatttttt acgattattg attttcgaaa
    19441 tgttaccaat ttgtttgctg accctgattt tgatggtgag ccagtgaagg tgctggaaac
    19501 aggtgcgaaa acagtcagtg gttctacgcc tggtttcgta ggtgaggaag gtgacccagt
    19561 agaaaaatat atcgttacag acaagcaggt taccattctt aattctactg ttcaagtatt
    19621 ggatgaaaac gggaaactga ttaccgaaag cctgaccgac tacactcgaa agaatatctt
    19681 aggtagctac gccactttga acgattttat cacagtttgg catacggcag ataaaaagaa
    19741 gcttatctta gacgaacttt ataaaaaagg agtttatcta gatgctattc gagagtcgga
    19801 gggaatatca gaacaagaaa tcgatgattt tgatttactc ctaaaacttg cctatggtca
    19861 aaaagaatta accaaaacgg aacgtatcaa taaactcaaa caaagcggat atttatataa
    19921 atatagtgag gaagcgcgtg ctgttttgga aattttactg aacaaataca tggataaagg
    19981 tattggagaa ctcgaaagca ttgaaacatt aaaacttcca gaatttcaga tatatggtgg
    20041 aaccttcaaa atcatcaata cttattttgg agataaaaaa cgatatttac aagcaattaa
    20101 agaattggag caagagctat ttacagtagc ttaatgaaag gaaagtatgt caattacatc
    20161 atttgtaaaa agaattcaag atatcactcg aaacgatgct ggtgttaatg gtgatgctca
    20221 acgtattgag caaatgtctt ggttattatt cttaaaaatt tatgatagcc gtgaaatggt
    20281 ttgggaatta gaagaagacg agtatgagtc aattatccca aaggaattaa aatggcgaaa
    20341 ttgggctcat gctcaaaatg gggaacgggt attgacaggc gatgaattac ttgattttgt
    20401 caataacaag ttattcaaag agttgaaaga gcttgaaata acttcaaata tgcctattcg
    20461 aaaaacgatt gttaaatcag cttttgaaga tgcgaacaac tatatgaaaa atggcgtctt
    20521 gttacgccaa gtcatcaatg ttattgatga agttgatttc aatagccctg aagatcgtca
    20581 ttcgtttaat gatatttacg aaaaaattct taaagatatt caaaatgctg ggaactcagg
    20641 agaattttat acgccacgtg cagcgactga ttttattgcc gaagttcttg acccaaaact
    20701 tggagaatca atggcagacc ttgcttgcgg aacaggaggc ttcttgactt cgactctgaa
    20761 ccgtttaagt agtcaacgta aaactagtga agataccaaa aaatataata cagctgtttt
    20821 tggtattgaa aagaaagcat ttcctcatct tttagcagtt acaaatctgt ttcttcacga
    20881 aattgatgac cctaaaattg ttcatggaaa tactttggag aaaaatgttc gtgaatatac
    20941 ggatgatgaa aaatttgaca ttattatgat gaatccacct tttggagggt cagaattaga
    21001 aacaataaaa aataactttc cagcagaatt acggagttct gaaacagctg atttatttat
    21061 ggctgtcatt atgtatcgtt taaaagaaaa tggtcgtgtt ggagttattt tacctgatgg
    21121 ttttctattt ggtgaaggtg taaaaactcg cttgaaacaa aaactggtag atgagttcaa
    21181 cttacatacg attattaggt tgcctcatag tgtctttgca ccgtatacag gaatccatac
    21241 gaacattctt ttctttgata aaacaaagaa aacagaagaa acttggtttt atcgtttaga
    21301 tatgccagat ggttataaaa atttctcgaa aactaagccg atgaagtcag aacacttcaa
    21361 tcctgttcgt gactggtggg aaaatcgtga agagattctg gaaggtaagt tctacaaatc
    21421 taaatcattt acacctagtg aattggctga gttgaattat aatttagacc agtgtggctt
    21481 tccaaaagag gaagaggaaa tcttaaatcc ctttgagttg attcagaatt atcaagcgga
    21541 aagagcaact ttaaatcata agattgataa tgtattagct gatattttgc agttgttgga
    21601 ggacaaataa tgacaccaga acaacttaaa gcaagtattc tccaaagagc gatggaaggg
    21661 aaattagtgc cgcaaaatcc caatgacgaa cctgcaagtg aattattaaa gagaattaaa
    21721 gctgaaaaag aaaaacttat cagtgaagga aaaatcaaac gagataaaaa ggaaactgag
    21781 atatttcgtg gtgatgatgg gaaacattat gggaagtttg ctgatggaag cactcaagaa
    21841 attgatgttc cttatgatat tcctgatact tgggagtggg tgaggatttc tacattggtt
    21901 gaaattgtca gaggtggctc tccacgacca atcaaagatt atcttacttc tgaagtagat
    21961 ggaataaatt ggataaaaat aggtgatact gaaaagggtg aaaagtatat aaataatgtt
    22021 aaagaaaaaa tcaaaaaatc aggacttaac aaaactagat ttgtaaaaaa aggtacattt
    22081 ttgttaacta attctatgag ttttggtaga ccttatattt tgaatgttga tggtgcaata
    22141 cacgatggat ggttggctat ttcgaactat gaaaactcat taaataaaga ttacctattc
    22201 tatattcttt catcaaatgt agtttattct caatttctat ctctaattag tggagctgtt
    22261 gtgaaaaact tgaatagtga taaagttgct tctattctta tccctctccc cccactatcc
    22321 gaacaacaac gaatagtaga agcaatcgaa tcagctttag aaaaagtaga tgaatatgct
    22381 gaaagttata atagactaga acagctagat aaagaatttc cagataaact aaaaaaatct
    22441 attcttcaat atgctatgca aggaaaatta gttgaacaag acccaaatga tgaatcagtc
    22501 gaagttttac ttgaaaaaat acgagcagaa aaacaaaaac tctttgaaga aggcaagatt
    22561 aaaaagaaag atttggacat ttctattgtt tcccaaggag atgataactc ttattatgag
    22621 gaagtacctt gtgaaatacc agaaagttgg gaatgggtga ggttaaacga tataacctcc
    22681 tacattcaaa gagggaagtc tccaaaatat tcaaatattc ctatataccc tgtgattgct
    22741 cagaaatgta atcaatggtc tggcttttct attgacttag caagatttat tgatcccgaa
    22801 acagttcata gttaccagaa agaaagatta ctaagggatg gtgatttaat gtggaattca
    22861 acaggtctag gtacgttagg acgattagct atttaccatg aaaataaaaa tccttatgcc
    22921 tgggctgttg cagatagcca tgttacagtt ataagagtct tatcgggggt tattaattgc
    22981 catttcatct ataattttct ttcctctcct attgttcagt cagttattga agaaaaagcg
    23041 tcgggtagta caaaacaaaa agaattatta acgaaaacta taaaagaata tttaatcccc
    23101 ctcccacccc ttcctgaaca atccagaatc gttgataaaa tcgaacaatt tttcgcccat
    23161 attgacgcac taatttagta taatagtttt acgtgcggtg gaatttctat caaacataag
    23221 ataggagttt tacgttgaaa gattttgaat tacatttgaa gaaagctggt ttagctgaaa
    23281 atactgtgcg ttcgtacctt tatggtgttc gatttttctt ggagaattac gaactcaaaa
    23341 tggaagattt atttgaatac aaaggatatt tattagacaa ttttaaacct aaaactgtca
    23401 atttgcgact acaaggagta aataaatatc tgacttttat tggtcatgat gatttgaaat
    23461 taaaatttgt caaagtacag caaaaaccgt ttttagaaga tgtcattagc catgctgatt
    23521 acctttttct taaacgtagt ttgaaaaaag atggtatttt aaaatggcat tttgtcgttt
    23581 ggtttttagg tgcaactggg gctcgtgtaa gtgaacttat taaactaaaa gtagagcatg
    23641 tagaaatcgg ttattttgac atttactcaa aaggtggtaa aattcgtaga ctgtacattc
    23701 ctaaaaaatt aagaaatagt tgtcttagtt ggttagaatc agaaaatcgt cgaagtggtt
    23761 atttattttt gaataaattt aacgaaccaa ttacagcaag aggagttgct caacagttaa
    23821 aaaattatgc tgataaatac aaaatgaatc ctaaagtaat ttaccctcat tcttttaggc
    23881 atttatttgc taagaatttt ttagcgaagt ataatgatat tgccttgctt gcagatttga
    23941 tgggacacga aagtatagaa actactcgaa tttatctaag gaaaacagct actgaacaac
    24001 aaaatattgt agataaaatt gttaattggt aaaaaataac aggtggtcaa actgactacc
    24061 tgctattttt gtgattatgg ctcttattat gggaataaag acgaaacaac ctcttatcct
    24121 atatatgaaa tcccagaagc atggagatat attaaatttg ctagcctagt taacttcaga
    24181 ataggaaaaa ctcctccacg cagtgaagct actttttggg gaactgaaat accttgggta
    24241 tctatatcag atatgcctat atctggttat gtaactaata cgagagaatc tatttctaaa
    24301 ttagcattaa aatcaaagaa aatagacatt tcacctaaag gaactttatt aatgagtttt
    24361 aaattatcta ttggaaaagt tgccatattg gatattcctg ccactcataa tgaagccatt
    24421 atatcgatat tcccctatgc taataaagaa aatattatca gagattactt aatgatattt
    24481 ttgccactta tctctacttt aggtgattca aaagatgcta tcaaagggaa aacattaaat
    24541 agtaccagta tctccgaatt attaatccct atttctaatc atgaagagat gaaaagaatc
    24601 atttccaaag ttgatttact ttttcaaaaa gtttctcaac tttttgagta ataagttcct
    24661 gttcctcaaa aggagctaac ggaattaata gctcgctcag tgtagtttta ggaatattat
    24721 ataaagcttg acctgatagt ttagttattg ctttcaattg tttataaaat aacggagagg
    24781 acaagttaaa taatagaaat tttgaaataa tctctgaact ttcgaatggt gttaattgga
    24841 aaataaatcc accagccaca acaccatcat agtctttatc gattcttgca aactttccaa
    24901 tatgttctaa agaggttgat acaggtgtta ttagctgatt atgttttaaa taaacttgct
    24961 cagaggagat gaattgtgta tcaatgtagt aatcgttatc caacagagaa aattctaaag
    25021 gcttaatatt accaccacgt ataattctaa cacctttatt attaatgctt aaatcgccct
    25081 tcttgtaaga aagacctgta ttcattgaaa aaatatcttt tatttttata acaacccaat
    25141 tcataggt
//
LOCUS       DAVMAH010000033        25094 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVMAH010000033 DAVMAH010000000
VERSION     DAVMAH010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25094
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.033"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(313..1212)
                     /gene="galU"
                     /locus_tag="VYO94_001285"
     CDS             complement(313..1212)
                     /gene="galU"
                     /locus_tag="VYO94_001285"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV1759923.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(1234..2250)
                     /locus_tag="VYO94_001286"
     CDS             complement(1234..2250)
                     /locus_tag="VYO94_001286"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1759924.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            2462..2842
                     /locus_tag="VYO94_001287"
     CDS             2462..2842
                     /locus_tag="VYO94_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1759925.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            complement(3016..3441)
                     /locus_tag="VYO94_001288"
     CDS             complement(3016..3441)
                     /locus_tag="VYO94_001288"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1759926.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(3509..4159)
                     /gene="phoU"
                     /locus_tag="VYO94_001289"
     CDS             complement(3509..4159)
                     /gene="phoU"
                     /locus_tag="VYO94_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1759927.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKTLLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(4174..4926)
                     /gene="pstB"
                     /locus_tag="VYO94_001290"
     CDS             complement(4174..4926)
                     /gene="pstB"
                     /locus_tag="VYO94_001290"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1759928.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(4928..5743)
                     /gene="pstA"
                     /locus_tag="VYO94_001291"
     CDS             complement(4928..5743)
                     /gene="pstA"
                     /locus_tag="VYO94_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1759929.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(5736..6599)
                     /gene="pstC"
                     /locus_tag="VYO94_001292"
     CDS             complement(5736..6599)
                     /gene="pstC"
                     /locus_tag="VYO94_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1759930.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(6717..7592)
                     /locus_tag="VYO94_001293"
     CDS             complement(6717..7592)
                     /locus_tag="VYO94_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV1759931.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(7759..9090)
                     /locus_tag="VYO94_001294"
     CDS             complement(7759..9090)
                     /locus_tag="VYO94_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV1759932.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(9091..9798)
                     /locus_tag="VYO94_001295"
     CDS             complement(9091..9798)
                     /locus_tag="VYO94_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1759933.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(9882..10367)
                     /locus_tag="VYO94_001296"
     CDS             complement(9882..10367)
                     /locus_tag="VYO94_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1759934.1"
                     /translation="MAPTDKEDLIRTLELAPHIEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            10353..10911
                     /locus_tag="VYO94_001297"
                     /pseudo
     CDS             10353..10911
                     /locus_tag="VYO94_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11226..12917)
                     /locus_tag="VYO94_001298"
     CDS             complement(11226..12917)
                     /locus_tag="VYO94_001298"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV1759935.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSTISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            13053..13499
                     /gene="argR"
                     /locus_tag="VYO94_001299"
     CDS             13053..13499
                     /gene="argR"
                     /locus_tag="VYO94_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1759936.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNGTEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDKWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            13550..16084
                     /gene="mutS"
                     /locus_tag="VYO94_001300"
     CDS             13550..16084
                     /gene="mutS"
                     /locus_tag="VYO94_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV1759937.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            16231..17925
                     /gene="patA"
                     /locus_tag="VYO94_001301"
     CDS             16231..17925
                     /gene="patA"
                     /locus_tag="VYO94_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV1759938.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(18256..18525)
                     /locus_tag="VYO94_001302"
                     /pseudo
     CDS             complement(18256..18525)
                     /locus_tag="VYO94_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            18717..20483
                     /gene="patB"
                     /locus_tag="VYO94_001303"
     CDS             18717..20483
                     /gene="patB"
                     /locus_tag="VYO94_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV1759939.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMGLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            20622..21311
                     /locus_tag="VYO94_001304"
     CDS             20622..21311
                     /locus_tag="VYO94_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1759940.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            21315..21494
                     /locus_tag="VYO94_001305"
     CDS             21315..21494
                     /locus_tag="VYO94_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759941.1"
                     /translation="MEHLVVLSFIFSKFLECGILLKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            21481..22830
                     /locus_tag="VYO94_001306"
     CDS             21481..22830
                     /locus_tag="VYO94_001306"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV1759942.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            22954..24414
                     /locus_tag="VYO94_001307"
     CDS             22954..24414
                     /locus_tag="VYO94_001307"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV1759943.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            24428..24862
                     /locus_tag="VYO94_001308"
     CDS             24428..24862
                     /locus_tag="VYO94_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1759944.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
     gene            24984..25055
                     /locus_tag="VYO94_001309"
     tRNA            24984..25055
                     /locus_tag="VYO94_001309"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25017..25019,aa:Glu,seq:ttc)
BASE COUNT         7472 a         4919 c         5357 g         7346 t
ORIGIN      
        1 tatgttcggc tcggttgatt taatttaacc atgactactc caacagttaa gtcaaattta
       61 aaattattta ttattttgga accattagaa acaacatagc aaagttaaaa taaggctttg
      121 tccgtacaca acttgaaaaa gtgcgcaccg attcggtgct tttttgtttt actatactaa
      181 tttattctac tcttatttta atgaaaaaac aaatacaagt atagcgtttt cattagtttt
      241 tattaaatag gtagattcaa gtagagaatt tacttaattt atgtgtggct aatctttata
      301 taaatgattt tgttattcct tctcagtcaa ttcttttcca agttggatga ggtaattctt
      361 caaatcatct ttgacttgtg gatgtttgag ggcgtagtcg atggatgttt tcatgaagcc
      421 aaacttgtct ccgacatcgt aacgagcccc tttgaactca cgagcaaata cacgttgtgt
      481 tttattgagg gtgtcgattg catctgtcag ctgaatttca tttcctgcac ctggagcttg
      541 cttttcgaga atctcaaaaa tttcaggcgt gaggaggtag cgtccgataa tagcaaggtc
      601 gctaggagcg tcctctggag ctggtttttc aacaaaggtt tcaacactgt aaagaccatc
      661 ttttccttcg ccttgcggag caataacccc gtaagcagat acttcgtcat gagggactgg
      721 catgacagcg atagtagacg cgtgggtacg ctcgtagtca tccatgagtt gtttggtaag
      781 tggaacagcc ttttcgtctg tgatatccat caagtcatca ccaagcataa cgacaaaagg
      841 ttcatttccg acgaaagcct tggcttgcaa aacagcatct ccgagaccgc gtggatgagt
      901 ttggcggata aaatgcagac gcatgccagt tgtttcatca actagcttca aaagatctgt
      961 tttccctttt tctttgaggt tatattccaa ttcgaagttt gaatcaaagt ggtcctcaat
     1021 agaacgtttt gatttaccag tgacaactag aatatcttca atacctgatt tgagagcttc
     1081 ttccacgata aactggatag ttggtttgtc tacgattggc aacatttctt tggcaagggc
     1141 cttggttgct ggtaaaaatc gagttcctag tccagcagca gggatgactg cctttctaac
     1201 ttttgatgtc ataaaaatcc tttctataga gggttaagac cactcatttt ctgctttaaa
     1261 ttcattgttc atgatgtcat aaatggcatc tttgatattg gttccgtgat aaataacttg
     1321 gtaaatagcc tgtgtaatgg gcatatagac tccaagttct tgggctagtt cataggctgc
     1381 tcgagtcgtt gaaattcctt cgattaccat gcccatatta gcttctatat cagctaggga
     1441 ttctcctcgt ccgagagcat ctccagctct ccagttacga gagtggatgg aagttcccgt
     1501 tacgatcaaa tctcccacac cagataagcc gctataggtc aatggactgg ccccgagtgc
     1561 tacccctagg cgggtgattt ctgctaaacc tcgagcgatg atggctgcct tagcattatc
     1621 accaaatcca agaccatgta aagctccagc accgacagca ataatatttt taagagcacc
     1681 agcagtttca accccgataa catccgtatt ggtataaagt cggaagtagt gattactaaa
     1741 tagcttctga acgtattgag ctgtttgtaa atctttagaa gcagcagtta ttaaagttag
     1801 gtcacgcaca atggtctctt ctgcatgact aggccctgaa acaacgacga tatcactacg
     1861 gagatgttca ggaatttctt cttcaagaat ggttgataat cgtttatggc tatcaggttc
     1921 taatcccttt gatgcgtgca tgatgataac cttatggtcc aaggtttgtg caacttgctg
     1981 ggcaacaagt cgtgtcactt ttgttgggac aacaaacaaa atcgcatcca catctttcaa
     2041 tgtttctgct aagtcggtgt aggcaatgat attttcgtct agaacgacat ctttaaagta
     2101 gtgcttatta gtatggtgtg tattaatttc attgatttgc tcgggaagat ttccccaaat
     2161 acgtacctcg tgtccattgt catttaagac ttgtgaaagg gcggttcccc aagaaccagg
     2221 ccccaagacg gcgacggttt gtttttccat gatttcctcc ttgatagagt tctttctctt
     2281 attctatcat attctagggg attttgcact tgcattactg gggtatggtg gaaaaataca
     2341 caaaaaccga gacgaaggga taaactctta gtctttagtt aaagtgagaa gaaatctgat
     2401 agatagtttg attcagtata tgcttataat agaggtaaac aactcaggag gttcttgtag
     2461 gttgcgagag tttggcgaaa aaattaaaag attacgtttg gctaaaaaaa tcagtcgttc
     2521 agaattttgt ggtgatgagt ctgaattaag tatccgtcaa ttaattagaa ttgaaaatgg
     2581 agaatccaga ccaacactaa caaagttaaa atatatcgct gaacgtttgg gggttgagga
     2641 ttacaagttg atgccaagtt atatagagtt ggataaggaa tacctagaat tgaagtattt
     2701 cttgatgagg actcctacat acgaagatga aactatcgcc caaaagaaag agagtgtttt
     2761 gataagattt ttgaagagta ttatgatagg ctacctgagg aagaaagatt tatcatccca
     2821 aattattcat atctggcact aacgaactac acagttcaaa aattaccaga aaagctagtt
     2881 gaaatactgt ccttctggtg attttgctta atttctgatg ttagagacat aattgaggag
     2941 atttgtcttg attttttcct aaaaaagggc agactcctcc cttggtttga tgctcgattt
     3001 ttaaaataag gtgacttatt ctgttaggca tgttttcccc tgccctctag ctctatatgg
     3061 aacagggagt atcagattta tctggcagat tgtatcaaat aaggcttgaa actgttttga
     3121 ataggcatat agacttgaga atttgagaat atgtcgtcta gcagtagaga catattttcc
     3181 ggcaatatga aggaagagac gtcgaaaacg cttgatagtc aaggccttta cttcatcacc
     3241 agctagctgc tttaaaaaga ggtagagatt ataagccaga cagcccatca tcatacgtac
     3301 ttcattctta atcatggtcg aactatctgt cttatcccca aagaatcctg ctttcctttc
     3361 tttgataaag ttttcagcat tccctcgttc acgatagaat tgaaacagct cctcactatc
     3421 tacactgctt aaattggtca aatgaacttt tttacaacca taaaaaagag cacttaatcg
     3481 tactcttctc ttttaaggat tagttgaatt aattcaaatc cactagttct cctgtttcta
     3541 ggtagactag gcgttcacaa atgttagcaa tgtaatcagc gaagcgttcc agatgcccta
     3601 tgatataaag gtattgtgtt ccattgggaa ttgaggtttc ttggtctttc ataagtccaa
     3661 tgatttcctt tgataaggca taataatatt ggtcaatctg ttcatctttt tgagcaatac
     3721 taatagcttt tgaggcttgg tgcaaaggaa aggcaaccaa taaatcggat agcatgctga
     3781 gggataattt acccatttgg tgtaactgtt cttcgtcagg ggctagttga ttttctttta
     3841 gttgcaaaac agctttagca atgcctgcca tatggtctcc catacgttca aggtctgaac
     3901 aagaagacat gatgctaatc acaaatcgaa ggtcagacac ttgtggctgc tgcaaggcca
     3961 acaaacgggc acaggtcaat tcgatagcgc tttgaccttg gttgatagca tgatccttat
     4021 tgataattag ctctgccatc tccttgtctt tggaggctaa ggccagtaag gtttttgaag
     4081 ctgtttcaag gacaagttgc cctagtccta aaaaggattg ttctaattca tgcaattcta
     4141 agtcaaattg atttctcata ggtttttcct tccttatccg aaccgtcctg aaatatagtc
     4201 ttctgtgcgc tgatcttttg gattggtaaa cacgtcaacg gtgtctccaa attcgcaaat
     4261 ttctcctgtt aagaaaaaag cagttttatc tgaaatacgt gaagcttgtt gcatgttatg
     4321 ggtaacaatg ataatcgtat aatccttttt tagttgctga atgaggtctt caatttttaa
     4381 agtggagata gggtctaagg ctgaagtcgg ctcatccatt aacagaacat caggttctac
     4441 tgctaaagct cgcgcaatgc aaaggcgttg ctgctgaccg cctgataagg acatggcact
     4501 ctttttaaga tcatctttga cttcgtccca aatggctgcc ccttttaaag atttttccac
     4561 taaggcatct aattgttttt tgtctcgaat accatgtgtc cttgggccat aagccacgtt
     4621 atcatagata gacatggcaa agggattagg ctgttgaaaa accatcccta cacgcttgcg
     4681 tagctgatta aggttgaatt tgctactata aatatcttgc tcatctaaga ggacttggcc
     4741 ttcaatatgg caagaaggaa ccaaatcgtt catccgatta agggttttta gaaaagttga
     4801 tttaccacaa ccagatgggc ctatcaaggc agtaatctgt ctttctggta attgaatcga
     4861 aatatttttt aaggcttgaa aatccccgta aaataagtct aggtgtctga ctgaaaatgt
     4921 tcccatacta ggaagctcct ttcacaagtt tccgagataa taagcttgat agagtattta
     4981 tcattaaaac agtaataatc aaaatcacgc cggtagcata ggcttcattg acatgtagcc
     5041 cctcacttga cagcatatac atatgtaggg ctagagaacg gcctgaagac atgagactac
     5101 ttggcgtatt ggtagaggta cctaatgtat acatgagggc agctgtttca ccaacgatac
     5161 ggccaatagc tagtatcact ccagctaaaa tacctggcat ggcaactggt agaacaattc
     5221 taaaaacagt ccgtaactta cctgccccaa gtccataact tgcttgacgc atgctatcac
     5281 taacagataa aagggcttct tctgttgagc gaataatgac tggcaacacc atgataactg
     5341 aggttaagat tcctgataac agagagtatt gaaaacctaa gaagactaca aagaagagca
     5401 tgccaaacag accaaaaaca atggaaggaa tcccagacaa ggtatctgag gccaatcgca
     5461 tgattttaac acaaagggaa tctttttttg tatattccac aagataaaaa ccagcaaaaa
     5521 tccctatggg caaggctaaa agaagagcac caaagaccag aataacggtg gaaataatcg
     5581 ctggcataag ggaaatgttc tcagaagtat aagtccaaga aaagagggat agacttagat
     5641 gaggtaagcc tttgatgagg ataaaaccaa tgattaaaaa gagagagcca aaggttaaag
     5701 ctgaaaaaca ataaacgaga agttttagca ggtatttact cataagatga ttttcctttc
     5761 aagtaggcaa agtaggcatt aatcaagaga ataaggaaaa agagaactgc tgaggttgca
     5821 ataagggctt ccctatgctg acctgatgcg taagccattt ccagaacaat attggttgtt
     5881 aaggttctgg ttcctgaaaa gagtccactt ggaataatcg gctggttgcc tgccaccaaa
     5941 ataactgcca tggtttcacc tactgcgcga ccaattccta aaataactgc tgataaaata
     6001 ccagatctcg cagctggcaa gatgacacta aaaatactcc gttcatgact agctcctaga
     6061 gccaagctac cagaataata cgttttggga actgttcgga tagcagattc tgacaaactg
     6121 ataatggttg gcaaaatcat tattcctaat agtaacgaag cggttaggac actcatgcca
     6181 tttcctaaaa agcttctaat ccaaggcacc aataattgta ggccgaaaaa accataaaca
     6241 atagatggaa tggccgccat caagttgata gctgatttta agaagccata gacgggcttt
     6301 ggacaataat aaaccataaa caccgatgtc aagatgcctg ttggcacccc aatcacaatc
     6361 gctcctaagg taattaataa ggaaccaacg atcattggta aaataccata gcttgccgga
     6421 atgttcgttg gcgaccaatc actgcctaat aaaaaacggg caaagccgta gttagccatg
     6481 aaaggtaagc cattactaaa aataaagaaa cagattagca aaatagctac aacagctact
     6541 gttgcactca tgaaaaaaat tgccctaaaa actgcttctt tgaaggcttg ttttgtcaca
     6601 tcttgtcctt tctagtgaag aaagtaaggg agatacgaca cctccctact tgccttcttt
     6661 atcttattgt acgatgaaac gtctgcatct ctttagagat ttatggagca aacattttat
     6721 ttaatcttgt cccaggtggt taatttgcca ctaaaaacgt ctgcaagttc agccatactg
     6781 acttggcttg ccttattgtc attattgacc acaacagcaa taccgtctaa agcaatagca
     6841 tcatgggtga gactcttacc ttcttcagga gttaattccc tagaaaccat accaatatca
     6901 gcggttttct ccttaacagc ggtaatacct gctgaagacc cattagaggt aatatcaatc
     6961 gtaacttctg gattttcttt tttataagct tctgctaatt tttccattaa agaagatact
     7021 gaagtggaac ctacaacaga caacttgcct gataagtgtt ggcttgtata ttctgtggtt
     7081 tcggttttag cttcaataaa tttattatct gtgaccactt gttgaccttg tttggagtgg
     7141 ataaagctga taaaatcttg acctagcttg gaaagattag aagaccaaac aatgttgaag
     7201 ggacgttgaa gagggtattc accatctaaa actgtgtctc gactagcctt gacaccatca
     7261 atctctaaag ccttgacaga tttcgttaaa gatcccaagg agatgtagcc gatagcatta
     7321 gcattccctt gaactgctga gagaacacct tctgtactat tttgaatcac agctgttttg
     7381 gcagtgttgt caattttttt atcaccgtct tttttgagaa tccctgtgat ttctgtgaag
     7441 gcaccccgtg ttccagagcc attttctcgt gaaatcacct caatcgttcc tgaagctgac
     7501 tgtttggaag cagctgactg attgccacag gcaacaagcc caaatcctga taagccaatg
     7561 gctgcaagag taagcatttt tttgaatttc ataataatca cctttatctc tatgtatttt
     7621 tcttgtgtag gcttactaca tttatagtct aacaagtctt tgtaaaggtt tatccctgat
     7681 tcatgtaaag attgtgtaaa gaatcaaaaa aagccacttt tgaaaaatgg ctgctcctaa
     7741 aaatagcttt aaaaattatt agtcctgtgc gaaagattgg ttaggaagaa aaatcgtgaa
     7801 gcaactgcct ctgccaagct gactcgtcac cgtgacttgg ccacctaata attgactgag
     7861 ttctttgaca atggcaaggc caagaccagt gccaccagtt tgtctgcttc gacctttatt
     7921 aactcggtaa aaacgttcaa aaatacgatc ctgctctaat tgactaatac caatccctgt
     7981 atctgataca gaaatcttaa tgccttcgtt caccttttgg gtcttgacct caatttttcc
     8041 cccttgttca gtgtaacgga tggcattgga taaaagattg agtaagattt gggaaagtaa
     8101 ttgactatct gatacgaggg tgacatcatc tggcacctgc acctttagct gtaaatcctt
     8161 cttcttgagc tgaggttgca agctttgagt caaatcctgt acaaattctg ccaaagaaag
     8221 ggtcgtccat tgtataggca tttgttgagc cttagataag gtaagaagat gctcaacaat
     8281 atgctcaaga cgcaaacttt ctttgtaaat aatgtctaga aagtcatcct tgagcgcttc
     8341 ttcttcagct gacatcccct taatggtttc agcaaagccc ttaatcgaag taactggtgt
     8401 cctcaattca tgggaggcat ttgagacaaa ggctaaattt aacttttcat aagttctaat
     8461 cgttgttaaa tcatatagca agacgagcac agcttccaca gattgggtgg ggctaaaaac
     8521 gggaactgct gtcacttcta aaatcaagtc accctcatga aacccactta cttcttgttt
     8581 taaccttgtt ttttgatcaa aggcttggtg aactaaattc cgaatatcca tccgtttgag
     8641 gtcatcaagt gaacttatgt cgccgtccac atcgggaaaa taatgaggca gagagcgact
     8701 ggataataac atctgacctt gagcggaaac taaaaacgtc cccatggtta ggtgcgacag
     8761 aagaacctcc attgtttcgg ctagatcctt gtattgctga tcctgttggg agactttggt
     8821 ttttaggcca gacacatact gagccaaaga ctttaagtct tcttgccctt tttctaaaaa
     8881 gtattcacta ctggtcaaga gaggttggtg caaggtctca aaagcaactt cccatttcca
     8941 aaggcaaaag agccagtagc cacctagtcc caaagaaagg gctagaagaa agagaccgat
     9001 gcctttactg atccaagtta atgccatccc tgcaatcaga atgaggctaa cacttagatt
     9061 gactagccaa aattgaaggt agcgtttcat ctataactcc ttgaacttat aaccataacc
     9121 ccgaatggtt cgaataaatt gaggggcttt aggattgtct tcaatttttt ccctcaactt
     9181 accaatatga acgtccacca aacgtgtttc ctgcccaaag tcataccccc agatacgttc
     9241 caaaagacgc tctctagtca gtgtcatgtt gggatgtttc ataagataga gcaagagttc
     9301 aaattctttt ggggtcaaac tcagtaactt attcgccttg tagacttcat gacgctcagg
     9361 gtatactttc aaggtcccaa atagccaaga atcgtcagcg atattatctg aatcatctcc
     9421 ttcttgttct cctttagttc gcctgaggac agccttgaca cgcgccagca attctctagg
     9481 gctaaaaggc ttggtcaggt agtcatcagc ccctaattcc aaggccaaaa ccttatcaaa
     9541 ttcatcactt ttcgcagaaa ccatcataat tggagttttg acgcctttgg ctctcagccg
     9601 cttacaaact tccatgccat ctaattgtgg taacatgata tcaagcaaga taaaatcaaa
     9661 gggttctgtt tctgccaaag ctaaggcctt ccgtccattt gtaaccaatt gagtagaaaa
     9721 gccttcctta cttaaatggt agtcaagcaa tttcagaatg tgttcttcat catccactaa
     9781 taagacttgt tttgtcatct attatctcct attggtaaca ttataacaca attatcagaa
     9841 atcctaacat tgctaaatca gattaaattt gcctatcaag actagtatct ggtcaaacgc
     9901 tcaatcatct ccttgtgctc tggataggtc gccagtagat ctaccctttc aaataattca
     9961 aaatcctcaa attcaaaacc aggagcaaca agacaagaaa ccagagcatc atccttatca
    10021 actgttgatc cccaaatagt gcccttagga acacagtagt gaagttgttg ccctttggat
    10081 atgtccaggc ctaaagtgac tgcttcgtag tgaccatctg ctgtaatcat gtgaacagta
    10141 agtggggatc ctgcatgaaa ataccagatt tcatctgctg tcaatcggtg aaaatgtgaa
    10201 ggattcgttt cttctaataa gaaataaata ctggtataaa gcgcccttcc cttaccagca
    10261 aggtttatag tgtctgaagc tttttttgtt tgtctaaaat agccaccttc aatatgggga
    10321 gctaactcta gagttcttat caagtcttct ttatccgtcg gagccaatgg gttgaagtaa
    10381 ctcttgttca aagtggtttt acgatttcaa gaactcctct cagttctgag gacacggtaa
    10441 tgattgatgc gacggaagta taaatcaatc gccctaaaaa aagaattagc gaatgattct
    10501 ggtaaaaaga aatgccacgc tatgaaggct caagcgattg tcacaagtca agggagaatt
    10561 gtttctttgg atatcactgt gaactattgt catgatatga agttgttcaa aatgagtcgc
    10621 agaaatatcg gacaagctgg taaaatcttg gctgacagtg gttatcaagg gctcatgaag
    10681 atatatcctc aagcacaaac tccacgtaaa tccagcaaac tcaagccact aacagttgaa
    10741 gataaagcct ataaccatgc gctatccaag gagagaagca aggttgagaa catctttgcc
    10801 aaagtaaaaa cgtttaaaat gatttcaaca acctatcgaa atcatcgtaa acacttcgga
    10861 ttacgaatga atttgattgc tggcattatc aatcatgaac taggattcta gttttgcagg
    10921 aagtctatta tttggttagg tgaattagtg aagcgtttag gcaagtgtct ctggttacga
    10981 cgtcatggcc tctaaatcga ttatatttag gggtcatgac tagtgaagca gttagctagt
    11041 tcgcatataa gcggctagcg tctaacaatt aggaacttta gttccaataa ctttaagatt
    11101 acgacgtttt aggacataaa tcgatcatat ttatgtccta aaactagtga agcgcctagc
    11161 caaagtccga ataggatttg gcgttagtta cttagattgc tttgcaatca agtaactttg
    11221 gcgatttaca tcttctctgg cgcttctact ccaagcaagc gaagggcttc tttgagaacg
    11281 actgcggttg cgtagctgag ggctagacgg ctgtcgcgtt ctgggctttc atccaagata
    11341 cgtgtatgtg catagtattt gttaaaggat tgagccaggc taattgcaaa tttagcaatg
    11401 atagaaggtt caaagttatc tgccgcacgg ttgataatac gtgggaagtc ttgaatgagt
    11461 ttaatgattt cccagctttc agtatcattc aagctatagt tgccagctgt ttctggtttg
    11521 aaatcggctt tgcgtaagat agattggata cgagcgtagg catattgaac gtaaggtcca
    11581 gtttcaccct cgaaggatac catagcctct aggtcgaagt cgtatccatt tgtacggtcg
    11641 gttttgaggt catagaattt aatggctcca accccaacag catgtgctac ctgatcttta
    11701 ttttccaatt caggattttt agcctcgatt tggaccttgg cacggctaac agcctctgca
    11761 acagtaggct ctagcaagat gacattccct ttacgagtag agagcttctt cccttctttt
    11821 gtaaccaagc caaaaggaac gtgagtaatg tcgtcactcc agtcgtagcc catctcttgc
    11881 aagacagctt tgagctgttt aaagtgggca gattgttctt gaccaacgac atagatagat
    11941 ttagcaaatt ggtattcgtt tttacggtaa agggctgcag ccaagtcacg tgtgatatag
    12001 agagttgcac catcagactt cttgataagg gctggatgtt caattccata tttctcaaga
    12061 ttcacaactt gggcaccttc tgattcaaga agtagtcctt tttcagaaag aatgtctaca
    12121 actgcatcca tcttatcatt gtagaaggct tctccgttat agctgtcaaa ttcaactttc
    12181 aattcattgt aaaggcggtt aaattccact aaactttcat cgcggaacca ttgccaaaga
    12241 gcgagagctt cctcatctcc attttcaagt ttacggaacc attcgcgcgc ttcttcatcc
    12301 aagctagggt cattttcagc ttcagcgttg atgcggacat agagtttaag gagttcatcg
    12361 attggatgag cttttacagc ttcttcgtcg ccccattttt tgtaggcaac aatcaacatc
    12421 ccaaattgtt taccccagtc tcccaaatgg ttgaccttga ccgtttgata accgattttt
    12481 tggaaaatat gtgacaagct atctccgata acagttgaac gcaggtggcc aatagaaaat
    12541 ggtttagcga tattcggact agacatgtcg ataacaacat tttcttgttt accaatattt
    12601 tggtcagcat agtgttcttt ttcagtggta acagcttgca atacttgagc agaaatggta
    12661 gatttatcaa ggaaaaagtt aacgtaaggt cctgttgcga caactttttc aaaggcttgg
    12721 ctgttcattt tttcagccag ttcagccgca atcatttgtg gtgctttacg ttcgactttg
    12781 gcaagagaaa aagcagggaa agcgatgtcc cccatttctg agtttttagg ggtttccagt
    12841 aactttaaaa tagcctcttg gtccaggcta tcaatgatgc tagccaattc gcttgcaatc
    12901 aattcttttg tattcattaa gagctccttt ttggactttt ctactatttt atcacaattt
    12961 taaagaaaga agaaaaaatt tttgaaatct cctgtttttt tggtataata tggttataaa
    13021 tatagttata aatatgcacg caagaggatt ttatgagaaa aagagatcgt catcagttaa
    13081 taaaaaaaat gattactgag gagaaattaa gtacacaaaa agaaattcaa gatcggttgg
    13141 aggcgcacaa tgtttgtgtg acgcagacaa ccttgtctcg tgatttgcgc gaaatcggct
    13201 tgaccaaggt caagaaaaat gatatggtgt attatgtact agtaaatggg acagaaaaga
    13261 ttgatttggt ggaatttttg tctcatcatt tagaaggtgt tgcaagagca gagtttacct
    13321 tggtgcttca taccaaattg ggagaagcct ctgttttggc aaatattgta gatgtaaaca
    13381 aggataaatg gattttagga acagttgctg gtgccaatac cttattggtt atttgtcgag
    13441 atcagcacgt tgccaaactc atggaagatc gtttgctaga tttgatgaaa gataagtaag
    13501 gtcttgggag ttgctctcaa gacttatttt tgaaaaggag agacagaaaa tggcgataga
    13561 aaagctatca cccggcatgc aacagtatgt ggatattaaa aagcaatatc cagatgcttt
    13621 tttgctcttt cggatgggtg atttttatga attattttat gaggatgcgg tcaatgctgc
    13681 gcagattctg gaaatttcct taacgagtcg caacaagaat gccgacaatc cgatccctat
    13741 ggcgggtgtt ccctatcatt ctgcccaaca gtatatcgat gtcttgattg agcagggtta
    13801 taaggtggct atcgcagagc agatggaaga tcctaaacaa gcagttgggg ttgttaaacg
    13861 agaggttgtt caggtcatta cgccagggac agtggtcgat agcagtaagc cggacagtca
    13921 gaataatttt ttggtttcca tagactgcga aggcaatcaa tttggcctag cttatatgga
    13981 tttggtgacg ggtgactttt atgtgacagg tcttttggat ttcacgctgg tttgtgggga
    14041 aatccgtaac ctcaaggctc gagaagtggt gttgggttat gacttgtctg aggaagaaga
    14101 acaaatcctc agccgccaga tgaatctggt actctcttat gaaaaagaaa gctttgaaga
    14161 ccttcattta ttggatttgc gattggcaac ggtggagcaa acggcatcta gtaagctgct
    14221 ccagtatgtt catcggactc agatgaggga attgaaccac ctcaaacctg ttatccgcta
    14281 cgaaattaag gatttcttgc agatggatta tgcgaccaag gctagtctgg atttggttga
    14341 gaatgctcgc tcaggtaaga aacaaggcag tcttttctgg cttttggatg aaaccaaaac
    14401 ggctatgggg atgcgtctct tgcgttcttg gattcatcgc cccttgattg ataaggaacg
    14461 aatcgtccaa cgtcaagaag tagtgcaggt ctttctcgac catttctttg agcgtagtga
    14521 cttgacagac agtctcaagg gtgtttatga cattgagcgc ttggctagtc gtgtttcttt
    14581 tggcaaaacc aatccaaagg atctcttgca gttggcgact accttgtcta gtgtgccacg
    14641 gattcgtgcg attttagaag ggatggagca acctactcta gcctatctca tcgcacaact
    14701 ggatgcaatc cctgagttgg agagtttgat tagcgcagcg attgctcctg aagctcctca
    14761 tgtgattaca gatgggggaa ttatccggac tggatttgat gagactttag acaagtatcg
    14821 ttgcgttctc agagaaggga ctagctggat tgctgagatt gaggctaagg agcgagaaaa
    14881 ctctggtatc agcacgctca agattgacta caataaaaag gatggctact attttcatgt
    14941 gaccaattcg caactaggaa atgtgccagc ccactttttc cgcaaggcga cgctgaaaaa
    15001 ctcagaacgc tttggaaccg aagaattagc ccgtatcgag ggagatatgc ttgaggcgcg
    15061 tgagaagtca gccaacctcg aatacgaaat atttatgcgc attcgtgaag aggtcggcaa
    15121 gtacatccag cgtttacaag ctctagccca aggaattgcg acggttgatg tcttacagag
    15181 tctggcggtt gtggctgaaa cccagcattt gattcgacct gagtttggtg acgattcaca
    15241 aattgatatc cggaaagggc gccatgctgt cgttgaaaag gttatggggg ctcagaccta
    15301 tattccaaat acgattcaga tggcagaaga taccagtatt caactggtta cagggccaaa
    15361 catgagtggg aagtctacct atatgcgtca gttagccatg acggcggtta tggcccagct
    15421 gggttcctat gttcctgctg aaagcgccca tttaccgatt tttgatgcga tttttacccg
    15481 tatcggagca gcagatgact tggtttcggg tcagtcaacc tttatggtgg agatgatgga
    15541 ggccaataat gccatttcgc atgcgaccaa gaactctctc attctctttg atgaattggg
    15601 acgtggaact gcaacttatg acgggatggc tcttgctcag tccatcatcg aatatatcca
    15661 tgagcacatc ggagctaaga ccctctttgc gacccactac catgagttga ctagtctgga
    15721 gtctagttta caacacttgg tcaatgtcca cgtggcaact ttggagcagg atgggcaggt
    15781 caccttcctt cacaagattg aaccgggacc agctgataaa tcctacggta tccatgttgc
    15841 caagattgct ggcttgccag cagacctttt agcaagggcg gataagattt tgactcagct
    15901 agagaatcaa ggaacagaga gtcctcctcc catgagacaa actagtgctg tcactgaaca
    15961 gatttcactc tttgataggg cagaagagca tcctatccta gcagaattag ctaaactgga
    16021 tgtgtataat atgacaccta tgcaggttat gaatgtctta gtagagttaa aacagaaact
    16081 ataaaaccaa gactcactag ttaatctagc tgtatcaagg agacttcttt gacaattctc
    16141 cacttttttg ctagaataac atcacacaaa cagaatgaaa aggagctgac gcattgtcgc
    16201 tcccttttgt ctatttttta aggagaaagt atgctgattc agaaaataaa aacctacaag
    16261 tggcaggcct tggcttcgct cctgatgaca ggcttgatgg ttgctagttc acttctgcaa
    16321 ccgcgttatc tgcaggaagt attagacgcc ctccttactg ggaaatatga agctatttat
    16381 agtatcgggg cttggttgat tggtgtggcc gtagtcggtc tagttgctgg tggactcaat
    16441 gttgtcctcg cagcctatat tgcccaagga gtttcatccg accttcggga ggatgccttc
    16501 cgtaaaattc aaaccttttc ttatgctgat attgaacaat ttaatgcggg aaatctagtc
    16561 gttcgaatga caaatgatat caaccagatt cagaacgttg tcatgatgac cttccaaatt
    16621 cttttcagac ttcccctctt gttcatcggt tcgtttatcc tagcggttca aaccttacct
    16681 tctctgtggt gggtgattgt tctcatggta gtcttgattt ttggtttgac tgctgtcatg
    16741 atgggaatga tggggcctcg ttttgccaag tttcaaaccc ttcttgagcg catcaatgcc
    16801 attgccaagg aaaatttacg tggcgttcgt gtggtcaagt cctttgtcca agaaaaagag
    16861 caatttgcta agtttacaga ggtctcagac gagctttttg gtcaaaacct ttacattggt
    16921 tatgcctttt cagtagtgga accctttatg atgttggttg gttacggggc ggtcttcctc
    16981 tctatttggc tggtcgcggg aatggttcag tcggatccgt ctgttgttgg ttccatcgct
    17041 tcttttgtta attacctaag ccagattatc tttaccattg ttatggttgg atttttggga
    17101 aattctgtca gccgtgccat gatttccatg cgtcgtattc gagaaattct tgacgcagag
    17161 ccagctatga ccttcaagga tatcccagat gaagagttgg ttggaagcct tagctttgaa
    17221 aatgtgacct ttacctatcc aatggacaag gaaccgatgc tgaaagatgt gagctttact
    17281 attgaacctg gtcaaatggt tggtgtagtt ggagcgactg gtgcaggaaa gtcaaccttg
    17341 gctcaattga ttccacgtct ctttgatcca cagaacgggg ccattaaaat cggtggcaag
    17401 gatattcgag aagtgagtga aggaaccctg cgtaaaacag tttccatcgt tctccaacgt
    17461 gccattcttt ttagtggaac gattgcagat aacttgagac aggggaaggg aaatgctact
    17521 ctatttgaaa tggagcgcgc agccaatatt gcccaggcta gtgaattcat tcatcgtatg
    17581 gagaaaacct ttgaaagtcc agttgaagaa cggggaacca atttctctgg tggacaaaaa
    17641 caaaggatgt cgattgcgcg tgggattgtc agcaatccac gtattctgat ttttgatgat
    17701 tcgacctcag ccttggatgc caaatcagag cgcttggtgc aagaagcttt gaataaggac
    17761 ttgaagggga cgacaaccat tattattgct caaaaaatta gctcggttgt ccatgcagac
    17821 aagatcttgg ttctaaatca aggacgattg attggtcaag gtacgcatgc agacttggtt
    17881 gccaacaatg ccgtttaccg tgaaatctat gaaacacaga aatgaaagac aaactataag
    17941 aaaagtcaat agttttatct aaactatttc ttatttcaat ttgatgattt ggcgatgatt
    18001 ttagagcacg gcaaaaggcc cttgaaaaag tccatttttt caaaggtaat cctgtgttaa
    18061 tttcagaaat tacatcactt tttgttcgtc aaatggcagc tcttttttta ggatataaaa
    18121 cagggttcgg ataagttttt ttgcaaggtg gatgatggct acattgtaat gttttccttg
    18181 ttctaattta gtcttaagat aggccttaaa agcaggcgaa aagcgagggc atactttggc
    18241 agcttgtatg agtacctacc gcagatgagg ggaactccgt ttgaccattc ttcctgctaa
    18301 atcaatctga tctgactgat aaatagaaga atccagtcca gcgaaagctt gtaattgagc
    18361 aggattatca aaggcatgaa tattttgaat ctcggctaaa atgaccgccc ctaaacgatt
    18421 cccaatccca gtaaccgtcg tgatgaccga gttgaactca gccatcaagt cattgacaca
    18481 tttttccgcc ttgtcaatga gcctcttgta atgtttgatg ttttcattac acgagataaa
    18541 acgtctatgc gttatcaaac tcattaccaa ttaaaacaaa aagctgtggt tagatccttt
    18601 cggaaattgt caagcgattg gaggaaatga actaatccac agcggcttat tccaagtata
    18661 ccacttgggc tttggcagta gctaactgcg ctaaatataa tataaggagg agtaaaatga
    18721 agacagttca atttttttgg cattatttta aggtctacaa gttctcattt gtagttgtca
    18781 tcctgatgat tgttctggcg acttttgccc aagccctctt tccagtcttt tctggacaag
    18841 cggtgacgca gctagccaat ttagttcaag cttatcaaaa tggcaatcca gaacttgtat
    18901 ggcaaagcct atcaggaatc atggtcaatc ttggcctgct ggttttggtt ctatttatct
    18961 ctagtgtaat atacatgtgt ctcatgacgc acgtgattgc agaatcgacc aacgagatgc
    19021 gcaaaggcct ctttggtaag cttgctcagt tgacggtttc tttctttgac cgtcgacaag
    19081 atggcgatat cctgtctcat tttaccagtg atttggataa tatcctccaa gcctttaacg
    19141 aaagcttgat tcaggtcatg agcaatattg ttttatacat tggtctgatt cttgtcatgt
    19201 tttcgagaaa tgtgacgctg gctctcatca ccattgccag caccccattg gctttcctta
    19261 tgctgatttt catcgtgaaa atggcacgca aatacaccaa cctccagcag aaagaggtag
    19321 ggaagctcaa cgcctatatg gatgagagca tctcaggcca aaaagccgtg attgtgcaag
    19381 gaattcaaga ggatatgatg gcaggatttc ttgaacaaaa tgagcgcgtg cgcaaggcaa
    19441 cctttaaagg aagaatgttc tcaggaattc ttttccctgt catgaatggg atgggcctga
    19501 ttaatacagc catcgtcatc tttgctggtt cggctgtact tttgaatgat aagtctattg
    19561 aaacaagtac agccctaggt ttgattgtta tgtttgcaca attttcacag cagtactacc
    19621 agcctattat ccaagttgca gcgagttggg gaagccttca gttggccttt actggagctg
    19681 aacgaattca ggaaatgttt gatgcagagg aggaaatccg acctgaaaag gctccaacct
    19741 tcactaagtt gcaagaaagt gttgaaatca gtcatatcga tttttcatac ttgcctgata
    19801 aacctatttt gaaagatgtc agcatttctg cccctaaagg ccagatgaca gcagttgttg
    19861 ggccgacagg ttcaggaaaa acgactatta tgaacctcat caatcgcttt tatgatgttg
    19921 atgctggtgg tatttatttt gatggtaaag acattcgtgg ctatgactta gatagtctta
    19981 gaagcaaggt gggaattgta ttgcaagatt cggtcttgtt tagcggaacg attcgagaca
    20041 atatccgatt tggtgtgcca gatgctagtc aggaaatggt tgaggtagca gcaaaagcaa
    20101 cccacattca cgactatatc gaaagtttgc ctgataagta cgatactctt attgatgatg
    20161 accagagcat cttttcaaca gggcagaagc aattgatttc aatcgctcga accctgatga
    20221 cagatccaga agttctcatt ctcgatgaag caacttcaaa cgtagatacg gtgacagaaa
    20281 gcaagattca gcatgccatg gaggtggttg tagcaggtag aactagtttc gtcattgccc
    20341 accgcttgaa aaccattctc aatgcagatc agattattgt ccttaaagat ggagaagtca
    20401 ttgaacgtgg taaccaccat gaacttttga agctaggtgg cttttattca gaactctatc
    20461 acaatcaatt tgttttcgaa taagaaagaa gttgtcctat gtgggcagct ttttcttgtc
    20521 cataaaaaat gtttatcaca gccttaaaaa aaacatatta gacgaaagtc attttgagtg
    20581 atatgatagg actatcgtta gcattcgaaa ggagaggcat catggctaga acggttgtag
    20641 gagttgctgc aaatctatgt cccgtagacg cagaaggcaa aatcattcat tcatctgtat
    20701 cttgtagatt cgcagagatc attcgtcaag tcggtggtct ccctttagtc attcctgttg
    20761 gtgatgagtc agttgtacgt gattatgtgg aaatgattga caaactcatt ttgacaggag
    20821 gccaaaatgt tcatcctcag ttttatggag agaaaaagac cgtcgagagc gatgattaca
    20881 atctggtccg tgacgaattt gaattggcac tcttgaagga agcgcttcgt cagaataaac
    20941 caattatggc aatctgtcgc ggtgtccaac ttgtcaatgt tgcctttggt ggaaccctca
    21001 atcaagaaat cgaaggtcac tggcaaggac tacctttcgg gacatctcac tctattgaga
    21061 cagtagaagg aagcgtggtg gctaagctat ttgggaaaga aagtcaggtc aactcagtcc
    21121 atcgtcaaag cattaaagat ttggcaccta atttccgtgt aactgctatt gattcaagag
    21181 accaaactat tgaagcgatt gagtctatcg acgagcaccg cattatcggt ttacagtggc
    21241 atccagagtt tctggttaat gaagaagatg gcaatttaga attatttgag tatttattga
    21301 atgaactgta acgattggaa catctggtcg ttctttcttt tattttttca aaatttttag
    21361 aatgtggcat tttactcaaa cgtttgaatt ctgataaaaa ttggagaaat tcgacaaaaa
    21421 aacttgaaaa aaacgaaggt aagcgttatg atagaaaaga agaaatattg gaggaagaac
    21481 atgtcacata ttaaatttga ttattcaaaa gttttagaca aatttgttgc accacatgaa
    21541 gtggaataca tgcaatcaca agtaacagca gcagatgaat tgatccgtaa aggaactggt
    21601 gctggtagcg acttcttggg atggttggac cttcctgaaa aatacgaccg cgaagaattt
    21661 gaccgcatct tgaaagctgc tgagcaaatc aagtcagaca gcgatgtttt ggttgtgatc
    21721 ggtattggtg gatcttacct tggtgcaaaa gcagcaatcg acttcttgaa tcaccatttt
    21781 gctaacttgc aaacaaaaga agaacgcaaa gctccacaaa tcctttacgc aggaaactca
    21841 atctcatcta cttaccttgc tgacttggta gagtatgttg cagacaaaga cttctcagta
    21901 aacgtaattt ctaaatcagg tacaacaact gaaccagcga ttgctttccg tgtctttaaa
    21961 gaactcttgg ttaagaaata cggtcaagaa gaagctaaca aacgtatcta tgcaacaact
    22021 gaccgccaaa agggtgctgt taaggttgaa gcagacgcta acggttgggg aacatttgtt
    22081 gttccagatg atatcggtgg acgcttctca gtattgacag ccgttggttt gcttccaatc
    22141 gcagcatcag gagctgacat caaagctctt atggaaggtg cgaatgcagc tcgcaaagac
    22201 tacacttcag acaaaatctc tgaaaacgaa gcttaccaat acgcagctgt tcgtaacatc
    22261 ctttatcgta aaggctatgc aactgagatc ttggtaaact atgagccatc acttcaatac
    22321 ttctcagaat ggtggaaaca attggctggt gaatcagaag gaaaagacca aaaaggtatc
    22381 tacccaactt cagccaactt ctcaactgac ttgcactcac ttggtcaatt tatccaagaa
    22441 ggaactcgta tcatgtttga aacagttgtc cgtgttgaca aacctcgtaa aaacgtgctt
    22501 attcctactt tggaagaaga ccttgacgga cttggttacc ttcaaggaaa agacgttgac
    22561 tttgtaaaca aaaaagcaac tgacggtgtt cttcttgccc acacagatgg tgatgtacca
    22621 aacatgtatg tgactcttcc agagcaagac gctttcactc ttggttacac tatctacttc
    22681 ttcgaattgg caattgccct ttcaggttac ttgaatgcta tcaacccatt tgaccaacca
    22741 ggtgttgaag cttataaacg taacatgttt gcccttcttg gaaaaccagg atttgaagaa
    22801 ttgagcaaag aacttaacgc acgtctataa tagaagaaaa gagtggtttg cccactcttt
    22861 ttactctctt tatccataga aattggactc agccaagact tgtgatataa tatagaaagc
    22921 aaaaaggcag acgcctagat aataggagaa actatgtcaa aagatatccg cgtacgttac
    22981 gcaccaagtc caacaggact actacacatc ggaaatgctc gtacagcatt gtttaattac
    23041 ttgtatgcgc gccatcatgg tggaacattt ctcatccgta tcgaagatac tgaccgtaaa
    23101 cgccatgtcg aggatggtga acgttcacaa cttgaaaacc ttcgctggtt aggcatggat
    23161 tgggatgaaa gtccagaatc acatgagaat tatcgccagt ctgagcgttt ggacttgtat
    23221 caaaaataca ttgaccaact attagctgaa ggaaaagcct ataaatctta cgttacagaa
    23281 gaagagttgg cagctgaacg cgaacgccaa gaagtagctg gcgaaacacc acgctacatc
    23341 aatgaatacc ttggtatgag tgaagaagaa aaagcagctt acatcgcaga acgtgaagca
    23401 gcagggatca tcccaactgt tcgtttggct gtcaatgagt caggtatcta caagtggcat
    23461 gatatggtca aaggcgatat cgaatttgaa ggtggcaata tcggtggtga ctggattatc
    23521 caaaagaaag acggttaccc aacttacaac tttgccgttg ccatcgatga ccatgatatg
    23581 caaatctctc atgttatccg tggagacgac catattgcta acacaccaaa acagctcatg
    23641 gtttatgaag cacttggttg ggaagctcca gagtttggtc acatgacctt gattatcaac
    23701 tctgagactg gtaagaagtt atctaaacgt gatactaata cacttcaatt tatcgaagat
    23761 taccgaaaga aaggttacct tccagaagca gtctttaact ttattgctct tcttggttgg
    23821 aacccaggtg gtgaagatga gattttctct cgtgaagaac tcattaaact ttttgatgaa
    23881 aaccgcctca gcaagtcacc agcagccttt gatcagaaaa aactagactg gatgagcaat
    23941 gattatatca agaatgcaga ccttgaaacc atctttgaaa tggcaaaacc attcttagag
    24001 gaagcaggcc gtttgactga caaggctgaa aaattagttg agctctataa accacaaatg
    24061 aaatcagtag atgagattat cccattgaca gatcttttct tctcagattt cccagaattg
    24121 acagaagcag agcgcgaagt catgacgggt gaaacagttc caacagttct tgaagcattc
    24181 aaagcaaaac ttgaagcgat gacagatgat aaatttgtga cagaaaatat cttcccacaa
    24241 attaaagcag ttcaaaaaga aacaggtatt aaagggaaaa atcttttcat gcctattcgt
    24301 atcgcagttt caggcgaaat gcatgggcca gaattaccag atacaatttt cttgcttgga
    24361 cgtgaaaaat caattcagca tatcgaaaac atgctaaaag aaatctctaa ataaagagga
    24421 tacaataatg gacatctggg aaaagatgta cgaagaagca cagaaactat acaatccaca
    24481 tgaagtatca gactttgttt atgccaatca tgttgtagct gcagtagaag cagaagatgg
    24541 acaaatattt acaggattct gtatggaggg aacctgtggt gttttccatc tctgcgcaga
    24601 acgggcggcc ctcttcaata tgtaccaatt ttcaggacaa actaaggtta agaaagtatt
    24661 agcctttcga gacaaaccac cttatggtgg aagttcagcc atgccttgcg gtgcttgtag
    24721 agaattcctt ttagagctta atgctgaaaa taaagatgca gaattcatga tggactataa
    24781 tataagaaaa acagttaaag tcgcagaact aatcccttat tggtggggag aagaacgtgc
    24841 ttctaagttt aatgagcgat agaagagtca gtataattct ggcttttttt actataagtt
    24901 gaaaaaataa aaaaaaatta gaaaaagtag ttgacaaaac ataaaaaggc tgtataatag
    24961 taagagttga aaataacaac tcaggtccgt tggtcaaggg gttaagacac cgccttttca
    25021 cggcggtaac acgggttcga atcccgtacg gactatggta tgttgcggtt ggaacacttg
    25081 atgaaaaaaa gttt
//
LOCUS       DAVMAH010000034        24018 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVMAH010000034 DAVMAH010000000
VERSION     DAVMAH010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24018
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.034"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(162..2033)
                     /locus_tag="VYO94_001310"
     CDS             complement(162..2033)
                     /locus_tag="VYO94_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1759945.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(2030..3214)
                     /locus_tag="VYO94_001311"
     CDS             complement(2030..3214)
                     /locus_tag="VYO94_001311"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV1759946.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKDIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(3226..3993)
                     /locus_tag="VYO94_001312"
     CDS             complement(3226..3993)
                     /locus_tag="VYO94_001312"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV1759947.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESEPEWQ
                     GIPVFKDKADLAGFEADVWIDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(4259..5107)
                     /locus_tag="VYO94_001313"
     CDS             complement(4259..5107)
                     /locus_tag="VYO94_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1759948.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(5109..5483)
                     /locus_tag="VYO94_001314"
     CDS             complement(5109..5483)
                     /locus_tag="VYO94_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV1759949.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(5557..6909)
                     /locus_tag="VYO94_001315"
     CDS             complement(5557..6909)
                     /locus_tag="VYO94_001315"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV1759950.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVNYYVDTITDVVRAEIGID
                     "
     gene            complement(6933..7712)
                     /locus_tag="VYO94_001316"
     CDS             complement(6933..7712)
                     /locus_tag="VYO94_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV1759951.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(7699..8556)
                     /locus_tag="VYO94_001317"
     CDS             complement(7699..8556)
                     /locus_tag="VYO94_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV1759952.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            8692..9657
                     /locus_tag="VYO94_001318"
     CDS             8692..9657
                     /locus_tag="VYO94_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1759953.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(9691..10602)
                     /gene="whiA"
                     /locus_tag="VYO94_001319"
     CDS             complement(9691..10602)
                     /gene="whiA"
                     /locus_tag="VYO94_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV1759954.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(10599..11576)
                     /locus_tag="VYO94_001320"
     CDS             complement(10599..11576)
                     /locus_tag="VYO94_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV1759955.1"
                     /translation="MRKPKITVIGGGTGSPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(11573..12463)
                     /gene="rapZ"
                     /locus_tag="VYO94_001321"
     CDS             complement(11573..12463)
                     /gene="rapZ"
                     /locus_tag="VYO94_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV1759956.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(12515..12895)
                     /locus_tag="VYO94_001322"
     CDS             complement(12515..12895)
                     /locus_tag="VYO94_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV1759957.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILVEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(12906..13493)
                     /locus_tag="VYO94_001323"
     CDS             complement(12906..13493)
                     /locus_tag="VYO94_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV1759958.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(13502..14734)
                     /gene="clpX"
                     /locus_tag="VYO94_001324"
     CDS             complement(13502..14734)
                     /gene="clpX"
                     /locus_tag="VYO94_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV1759959.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(14766..14936)
                     /locus_tag="VYO94_001325"
     CDS             complement(14766..14936)
                     /locus_tag="VYO94_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759960.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            complement(14936..15442)
                     /locus_tag="VYO94_001326"
     CDS             complement(14936..15442)
                     /locus_tag="VYO94_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV1759961.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGIGRRLLPQRETLILTRNLEETIDGVATFHDVQSVLDWYQAQEKNLYILGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(15572..16090)
                     /locus_tag="VYO94_001327"
     CDS             complement(15572..16090)
                     /locus_tag="VYO94_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV1759962.1"
                     /translation="MVELKKEAAKDVATLTKAAPLALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMRGRGFMVWHPKMDEYMDALDGHLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            complement(16589..18093)
                     /gene="lytC"
                     /locus_tag="VYO94_001328"
                     /pseudo
     CDS             complement(16589..18093)
                     /gene="lytC"
                     /locus_tag="VYO94_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
     gene            complement(18131..18889)
                     /locus_tag="VYO94_001329"
     CDS             complement(18131..18889)
                     /locus_tag="VYO94_001329"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV1759963.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            complement(18987..19664)
                     /locus_tag="VYO94_001330"
     CDS             complement(18987..19664)
                     /locus_tag="VYO94_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV1759964.1"
                     /translation="MTYLDAFKSGALVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            complement(19673..20617)
                     /locus_tag="VYO94_001331"
     CDS             complement(19673..20617)
                     /locus_tag="VYO94_001331"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV1759965.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            complement(20799..21311)
                     /locus_tag="VYO94_001332"
     CDS             complement(20799..21311)
                     /locus_tag="VYO94_001332"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV1759966.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            complement(21399..22157)
                     /locus_tag="VYO94_001333"
     CDS             complement(21399..22157)
                     /locus_tag="VYO94_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1759967.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            22365..22511
                     /locus_tag="VYO94_001334"
     CDS             22365..22511
                     /locus_tag="VYO94_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759968.1"
                     /translation="MEIKEQTRKLAVSCSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEY"
     gene            complement(22658..23788)
                     /gene="ugpC"
                     /locus_tag="VYO94_001335"
     CDS             complement(22658..23788)
                     /gene="ugpC"
                     /locus_tag="VYO94_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV1759969.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
BASE COUNT         6922 a         5576 c         4396 g         7124 t
ORIGIN      
        1 aaaggacgaa atttgtcctt tctcgagctt agctgacttc aacccactac agttgacaaa
       61 gagtctaaaa atcaaagtgc aaattaggaa gccggtcaca ggctgtactt gagtcggcaa
      121 tgtgaagccg acatagtttg cactttgatt ttcgaatagt cttaactatc aaattcactg
      181 agatactcat agcgttcgta tttttcaagg agtgcttcat ttttctcatc caattctttt
      241 tggagagtag ccagcttacc aaagtcagag ccgttagcct gcatttcctc ttcaatagca
      301 gcgatacgtt tttccaaggt ttcaatatca ccttcaatac ttgcccactc ctgcttttct
      361 tggtaggtca tgcgtttctt gtcttctcga accttgacca ctttttcctt ttcggccttt
      421 tgcacttgat tggccatatc tgtttcaaaa gctttttcat caagatagtc ggtgtaatga
      481 ccaaagaaag gacgaatctt gccatcctca aaagcgagaa tcttggtcgc taccttatcc
      541 aagaaatagc ggtcgtgact gactgttaaa acgggacctg caaaaccttg caagaaattc
      601 tctaagactg tcaaagttgc aatatctagg tcattggttg gctcgtctaa aagaagaaca
      661 tttggttttt ccaaaagcag tttgaggaga taaagacgtt ttttctcacc ccctgacaat
      721 ttctcaatca aggttccatg cgtcgaacgt gggaaaagga actgctccag caactctgca
      781 atcgaagtcg tagaaccgcc actggtcttg acctcttctg ccacttcctg caagtaattg
      841 ataactctct tgctttcatc caaaccctca atttgctgag agaaataggc gatgcgaaca
      901 gtttccccaa tcacaacttg tcctttagtt ggctcaagac ttcctgcaat caagttgagc
      961 agggttgatt ttccaacacc attgtcccca acgattccga tacggtcttt ggcctgcacc
     1021 aagagattaa aatcttgcaa aataggcttg ttttcatagg caaaggaaac agcctgaaac
     1081 tcgatgactt tcttcccaat ccgactggtt tcaaagttca tggtcaagtc tgtctcagca
     1141 ctactgcctg aaacttcctt tttcagatca tggaatcgat tgatacgggc ctgctgcttg
     1201 gtcgcacgcg cctgcggttg tctgcgcatc caggccaatt cttgtttgta gagttgttct
     1261 tttttgtgaa gaagagccgc gtcgcgctca tcctgttccg cctttaggcg aacatagtcc
     1321 tggtaattgc cctggtactc ggtcaagcct gcacgatcca actcgaaaat ccgtgttgac
     1381 aaagcgtcta agaaataacg atcgtgagtg ataaaaagga cggtcttctt agaatttttc
     1441 aaaaagaggg tcagccactc aataatcgca atatccagat ggttggtcgg ctcatccaaa
     1501 agcaagaggt cgtggttgcc aagtaagact tgtgccaact gtacccgtct tctcagacca
     1561 cctgacaatt ccccaacagg agtagataag tcttgaatgc ccaatttgct aagaacggtc
     1621 ttgacctgac tttcgatttc ccaagcttgg agagagtcca tctctgccat gacacgttcc
     1681 aaacgcgcct gcttgtcctc actatagtcg agcataatca attcatactc acgaatgagc
     1741 tggatttcct tgagttcact agatagaacc gtatccaaaa ctgtctttct atcatcaaaa
     1801 tcaggatcct gagtcaagta accaatctgg taatcatttt tagctgaaaa aggactaaca
     1861 tccccatcaa atccagaaac accagaaagg acgtccaaaa gggtggtctt gccagtccca
     1921 ttgacaccga ttaaaccaat tctgtctaag tcatggataa taaaggaaat atccctaaaa
     1981 acggtcttgt caccaacgga tttacttagt ttttcaacga taaaatcact cattttttct
     2041 ccctcaggta agcatggatg gcttcacgat tattctccaa ttctccatcg acaatggcaa
     2101 actcaatctc tgttaaaatc tctcccaagt ctgggcctgg ctgatagcca tattccttga
     2161 tcaaaatacc gccattaatc tgaatatctt tcttgtcatg gatagtcaag ctttggtatt
     2221 tttctgtgat ggcttgtggg ttgacttctt ttccttgagc ttgacgaaga ttttcagcct
     2281 gtaaaagcaa atctatgtca aagcgataac aatctcgctt gctcaattct ccattttcac
     2341 gcagagccaa aataatcagc aaatcctgaa cttgcttggc aaactggcgt gaggtcttcc
     2401 aagatttcaa aaatgactgc gcattttcaa tctccaaagc ccatagtaaa gccgcccagg
     2461 cttgttcaga ggattcaaaa gtaaaatcag tctccaaatc aaacagtctg ttgagcttgt
     2521 cctggctaga tgccatatca gggagatagt cataagcttg actctcaatc atggaagcca
     2581 agccccttct ccaaaatgga gccagcaaga gtttatcaaa ttcgacgaag gtacgctcta
     2641 cagaaatttt ctccaaaagc ggcgtcaagg tcttcatagc tttaaatgtt tctggctcaa
     2701 gtgcaaaacc aagactagcc tgaaaacgga aaccacgcat aatccgtaaa gcatcttcgt
     2761 tgaaacgctc actagccact ccaactgctc gcaagacttg cttttccaaa tcttctaaac
     2821 catggaacaa gtcaacgatt tctcctgtct catccaaggc aaaggcgttg actgtgaaat
     2881 cacggcgttt gaggtcttct tctagcgagc gcacaaagga aaccgcactg ggtctgcgat
     2941 agtccacata gacatcctct gtccgaaagg ttgttacctc atactcctca tccccatcta
     3001 agaccaagac ggttccatgc tcgattccga tatcggctgt tcgcggaaaa atctgcttgg
     3061 tctcttctgg ataagaagac gtcgcaatat ccacatcgtg gatagggcta tggagaaggg
     3121 catctcgaac agagccccca acaaaataag cctcaaagcc tgcttcttta attttttcta
     3181 atactggtaa agccttctga aattcagaag gcatttgcgt taatctcata ataagtgttc
     3241 taatccatag acaagctcat gacgcttgac aacttcttta attcccaaat tgactcctgt
     3301 catgaaggag atgcgatcat aggagtcatg acggagggtc aacccttctc cctgattgcc
     3361 aaagatgact tcctgatgag ctaccaagcc tggcaaacga actgagtgga tgcgcatacc
     3421 atcaaagtca gcaccacgag caccagcaat cagctcttcc tcatctgctg caccttgctg
     3481 aattgactct cgaacctctg ccatcaactc agctgtttta atggctgttc cactcggagc
     3541 atcctttttc ttgtcatgat ggagctcaat aatctccaca tttgggaaat atttggcagc
     3601 ctgcgtcgca aattgcatga gtaagacagc acccaaggca aagttagggg caatcaggcc
     3661 acccaagtct tgggcacgag aaaattcttt tagctctgca atttcttcac tcgtgaaacc
     3721 agtcgttcca actactggag caaagccatt ttcaagagca aaacgtgtat tttcgtaggc
     3781 aacagctgga gtagtaaaat ctatccagac atccgcttca aaaccagcta aatcagcctt
     3841 atccttgaaa acaggaatac cctgccattc tggctcagac tcaaaaggat ccaaaactgc
     3901 taccaagtcc aagtctggat cagtcaatac catctgacaa gcagcctggc ccatctttcc
     3961 cttaaaaccg gcaataatta ctcgaatact catctctact cctgtccaaa atacaaagcc
     4021 tgtaagaaca caaagtgaaa ataggaattc tgatcaagaa gtgtctactt cttggaagaa
     4081 ctatcttttt cacacagggt tccaggcgtg ttcaattatc aagatacaaa ggaccttagc
     4141 tgcccctgaa aaatagggaa tggcactgac tttccacgaa aggcaagaca ggcatctttt
     4201 ttcaagaggc aggtagtccg tgttcaattt ctaagattaa ctagcctaga agtgccaact
     4261 aaatcactgg aatataacct agagcaatac ttcctgctcc taggtgcgtt ccaatgacac
     4321 taccaaatgt agcaagtgaa acatccgaac ccaagccaaa atcaagcaaa tgctgacgca
     4381 attcttcagc cttttcagga gcattcccat gaatgacaat gacccggtat tgacctgaag
     4441 ccgttgtttc cttgataatt tcaattaagc gtttggtggc cttcttttca gtacgaactt
     4501 tttcgtaaac ttcaatcaca ccttgatcgt taaaataaag gattggctta atgctaagca
     4561 aattgcccaa aatggcagcc ccatttgaaa ggcgtccacc ttttaccaaa tgatccaagt
     4621 catctaccat gataaaggct gacgtacggc tgatttgaat ggctagctta tcctgaatgc
     4681 tggcaaaatc atcgccctga tcacgccaat taaagacgct ttcaaccatg atgcctaggg
     4741 gagcacttgt aatcaaagtg tctgggaaag caatggttaa gccctcatag tcatcgacca
     4801 tatactggat attttggtaa aaacctgaaa ttccagaaga taggaaaagc cccaaggcat
     4861 gtgtatagcc ttgttctttg agcgaagtta agatttcatc taacttggca atacttggtt
     4921 gactggtctt aggcaattca gaagcctgag ccattttttg gtaaaattcc tcagcagaca
     4981 gattgatgcc ttcgacatat tcctcaccat caatattgac aggaatatcc aagacaaaca
     5041 agtcttctct ttgcaagatc tctgcactga gataagcaga ggaatctgtg aaaacagcta
     5101 atttcatatt agaactccaa attaattcct ggtaagtcta atgcaatttc agtcacttcg
     5161 taagtcaaac gattgagcat gttcaaacat ggacgagcca aggtttccac ctcttcttgg
     5221 ttcaattcac ttggttcatt gacaatacgg ccatcgatat ggtttacttg tgagattgtt
     5281 ccactaatga caaacttatc aaatacaatc ataaagctca agatgacaat caaggaagtc
     5341 acttgatttt cttggtcatg ttggagcaat tggaaattca catccacctt ggtttcagga
     5401 gctccatttt cattttccca ttcaaaatta cgcgcatcaa aatgatactg actaacaaat
     5461 tcttgttcac gtttaagatt catgtctttc tccatcggct acaatattat aagctattgt
     5521 accataattt tttattttca tctagttttc taggatttag tcaatcccaa tttcagcacg
     5581 aactacatct gtgatggtat caacatagta gtttacttct tctgttgtag gcgcttctgc
     5641 cataacacgc aagaggggtt ctgttccact tggacgaaca aggatacggc cgttccccgc
     5701 catttcttct tccatcttct cgatgatggc cttgatagct ggcacttcca tggccttttc
     5761 cttcatgacg ttttccactc ggatattaac taatttttgt ggataaatcg ttacttctgc
     5821 cgccaactct gataagctct taccagtttc cttcatgatt ttagtcaatt gaactgctga
     5881 taattgacca tcacctgtgg tattgtaatc catcaagata acgtgaccag actgttcacc
     5941 accaaggttg tagcctgatt ttctcatttc ttcaacaacg tagcggtcac caactgcagt
     6001 aactgccttg ttaatacctt cgcgattcaa ggccttgtgg aaaccaaggt tagacataac
     6061 agttgtcaca attgtatttt gagccaattg tcctttttca gaaaggtatt ttccgatgat
     6121 gtacataatc ttgtcaccat caacgatgtc accattctca tcaacagcaa tcaagcggtc
     6181 actgtctcca tcaaaggcca aaccaatagc tgacccactt tctttgacca cttcttgaag
     6241 ggcttctgga tgtgttgaac caacattaag gttgatgtta agaccgtctg gtgtttcccc
     6301 gataaccgtc aattgggcac caaggtctgc aaagatttga cgggcactgg tagaagctgc
     6361 tccattagct gtatccaagg caaccttcat tccatcaaga ggagttccag ttgaaacaag
     6421 gtatccttca tacttacgca agccttctgg ataatctacc aaaattccta agccttctgc
     6481 acttggacga ggaagagtgt cttcctcagc atctagcaag gcttcaattt ctgcttcttt
     6541 ttcatcatct agtttgaagc catcaccgcc aaagaacttg attccgttat caagggctgg
     6601 gttgtggcta gcagaaatca tgacaccggc acttgctcct tcagtttcaa ccaagtaagc
     6661 tactgctggt gttgcaagga caccaagttt gtatacgtga atccctactg aaaggagacc
     6721 tgccaccaag gccgattcca acatttcccc tgaaatacgt gtgtcacgtc ctacaaagac
     6781 tttcggcgct tccgtttcat gttgactaag aacatagcct ccaaaacgtc ctagtttaaa
     6841 ggctaattct ggtgttagtt ctaggttagc ttctccacgg actccatcag tcccaaaata
     6901 tttacccatt gttataaaat ccttttctat ttttaattcg tttttgaact agttgctttc
     6961 gttgacgaag atgtctccga tgaactgctt gtacttgaat ttgatgtgct tgaacttggt
     7021 gctactggtt ttgtagtcac cttcattatt gtatcaaacg gagtgataac tgccggtaag
     7081 acaacaccat tgcggtcgat tgcctgcaaa ggtactgaac cactgtaatt acctgttata
     7141 cgttcgctag ttggcaaaac agcgataatc ttatcaattc tatccaatgt ctcttggtca
     7201 ctcgtaatag acacttcttt atctgacacc atgacatttt caatttgtac ccgactatca
     7261 atttgactag ggtcaatctc tggtacaatc tttaccttat ccttctgagc cttcttacca
     7321 atcttgactg taattttttg cggagtcgcc acagcggtca gcccattggg taaatcttca
     7381 atgctcaaag gaacttcaat cgttccaaca ccggcatctg ttaggtcagc agtaaccttg
     7441 aatttacgtg tactttcttg catttcacta gctagcgata ggcgatttgc accagtcaag
     7501 accactgata cttctgaagc aaaaccgcta ataaaatact tatcactatt atagcgtatg
     7561 tcaataggga catttgttac tgtattagta taggtttccg tttttacctg cctagcactg
     7621 gtactgtttt gaaaattcgt cgccgtagca tagacaaata agacacaagc aaaaaagagt
     7681 gaggatatga tatataaact attttttttc atgtttccat cctcctagca atcgttcttt
     7741 aaaactaaga cccacttcct cttttggaag taagatttca cgtaattctg tttcaaattc
     7801 atcaagtgtt aggttgtgct taaaccttcc attataggtt atcgaaattc ctcccgtttc
     7861 ctctgatacg acaaaagtca aggcatctga gacttctgat aaaccgatag ccgcccggtg
     7921 tctggtccca aattccttgg aaatccctgt gttttttgtc aagggcagat aggcagacgt
     7981 cacagcgata cgttcttctt tgataatcac cgcaccatca tgtaggggag tgttgggaat
     8041 aaaaatgtta atgagaagtt ctgcagaaat cttagcatcc aagggaattc ctgtcgaaat
     8101 atactcctgc aaggtacgta cacgctgaat agcaaccaag gccccgattt tacgaggact
     8161 catgtattca acagacttaa caaaggcacg aatcatctgt tcctcagcac taataggggc
     8221 attggaaaag aaatctgtcg ctcttcccaa acgttccaaa ccagtccgaa tctctggaga
     8281 gaagataaca accgccgcaa taaccccata agtaataatt tgattgatta accaagaaat
     8341 cgtagtcaaa ccaatcatat ttgcaaggat ttgagctaaa ataaacacca aaactccacg
     8401 taccaaaatc ataatcttgg ttcctgcaat agcttttgta aaatggtata aaatataagc
     8461 aacaatcaaa atatcaatca gattgatagc tatcgtccat ggacttgcaa acaaactggt
     8521 ccaatattgc agattggata attgttgaaa attcatccct gatatcctcc ctatcaaaac
     8581 actttcgtcc tattatacca ttttctggca tttttttccc tatcctagtc cattttacat
     8641 tgaacaaaaa tatgataaaa taaactgact aaaaaaaaca aaggagaaac tatgtctcaa
     8701 ctctatgata ttaccattgt gggtggtggt cctgtcgggc tttttgcagc cttttatgcc
     8761 cacctacgcc aagccaaggt tcaaatcatc gactctcttc cccagctagg tggacaacct
     8821 gctattctct accctgaaaa ggaaatccta gacgtaccag gcttcccaaa cctgactgga
     8881 gaagagttga ctaaccgctt gattgaacag ctaaatggat ttgatacccc tattcatctc
     8941 aatgaaacgg ttcttgagat tgacaaacaa gaagaatttg ccatcacaac ttctaaagga
     9001 agtcacctga ctaaaacagt tatcatcgct atgggtggcg gtgccttcaa accacgtccg
     9061 ctggaacttg aaggggttga gggctatgaa aatatccact accacgtttc taacattcag
     9121 caatacgctg gtaagaaagt gacgattctt ggtgggggag actcggctgt ggattgggct
     9181 ttggcttttg aaaaaatcgc accaactacc cttgttcacc gcagagataa tttccgtgcc
     9241 ttggaacaca gtgttcaagc cttgcaagaa tcatctgtaa ccatcaagac accattcgcc
     9301 cctagccaac tccttggaaa tggaaaaaca cttgataaac ttgaaatcac aaaagtcaaa
     9361 tctgatgaaa ctgaaaccat tgacctagac cacctctttg tcaactatgg tttcaaatct
     9421 tctgtcggta accttaaaaa ctgggggctc gacctcaacc gtcacaagat tatcgtcaac
     9481 agcaaacagg aatccagcca agcaggtatc tatgctatcg gtgactgctg ctactatgac
     9541 ggaaaaattg atctgattgc gacaggcctc ggagaagctc caactgctgt caacaacgct
     9601 atcaactaca ttgaccctga acaaaaagta caaccaaaac actctactag tttataaaaa
     9661 agaaccacga gtcacatagg attcgtggtt ttataattca tccgctatct tattgatttt
     9721 tctgagtctg tgattgacac cacttttggt cagaggggtg ctgagactat ctgctaactg
     9781 ctggatagag tagtctgggt gctgaatcct cagttgcgcc acttcctgca aatctactgg
     9841 caaattttct aagcccatga tatctttgat tttactgata ttgttaatgg tcttcatgct
     9901 ggcagaaact gtccgagcga tattagctgt ctcggcatta ttagcccgat tgaggtcgtt
     9961 acgggtttct cgcaaaatct taacccgctc aaaatcatca cgtgcctgca tggctcctat
    10021 tactatcaag aagtccataa tgtcttctgc tcgctggaga taggtcacag cccccttctt
    10081 gcgctcaagc accttggcat ccagtaaaaa ctgttggaga agggaggcaa ttccttgcgc
    10141 gtggtccaga taaacagaac tgatttccaa ctggtacttg cctgactcag ggtcacgaat
    10201 gctcccattt gccaagaaag cgccacagag ataggcacga cctgcttcct catccgataa
    10261 aatcgcctca tcaatacctg tttccaggcc aaagaaagag tctgccaagt gcaaatcact
    10321 taacaaatcc tgcacctttt catctgtaaa aacggtatag acgcgattct tgcgaagatt
    10381 gctccgttgg tggtgacgaa tttcagattt gatttcatag aaatggagaa aggactcata
    10441 gaggtgacgg gccagtttgg cattttctgt cacaactgac aaagtcaagc ccgaagtcga
    10501 gagaccgatg ctaccagaca ttttgataat ggcagataat tcatgccggc tcagatggtg
    10561 ttggcccagg atttcttctt ttactgctac tgtgaaactc attttttcac ctgtataatg
    10621 cgcatcaact cgtccacaat caaatctcca tcgtggaagg caccgccatt ttccagacga
    10681 aggaagttag atgaaatcac gcgcgaaact tgcttacaaa gacctacaaa atcgtgttcc
    10741 acttgcacca agtattcatc aaaacggttg gaattcatgt attcctgagg cactttttca
    10801 atattcacca agacagtgtc gataaaaggg cgaccaaggt gacgatgcaa gacttccacg
    10861 tggtcgctat ctgtaaagtg ttccgtctcc ccacgttggg tcatgatatt gcagacatag
    10921 gcaatttctg ccttagtttc caaaagagcc cgcccaattt ccttaatcac gatattgggc
    10981 aaaatagagg taaagaggga acctggccct aggacaatca tgtcactttc aaggatggtc
    11041 tgcactactc gacggctggc cagaggcgta tcatcgttta gggcattggt cacatagaca
    11101 ttgtcaatta tgcctcgatg gtctacaata tgactctctc cagccacttc tgtcccatcc
    11161 tgaaagactg catgaagggt caaaggatgg tcactggaag gataaatttt ccctgttgta
    11221 tggaaaaatt tgctcaataa ctgcatggca ttataggttg aaccctgcat ttctgacaag
    11281 ccagcaatga tgagatttcc caatggatgg ccagcaaagg ctccggcatc ctcagagaac
    11341 cgatactgaa agaccttctc ataaaactta ggcatatccg acatggccac aaggacatta
    11401 cgaagatcac ctggcggtgt caactgttgc atattttttc ggagttcacc tgaagaacca
    11461 ccatcatctg ccaccgtcac gatagctgcg atttccacat ctttttcccg cagacttttt
    11521 agaatgacgg gacttccagt ccctccacca atcaccgtta tctttggttt tctcatgaac
    11581 ggtttaccgt ttcctttctg cggtctttgt cgcgatgccc ttcattaaca gaccaattct
    11641 tggataagtc ctgcgccaag cgtttagcaa atgccacact acggtgttgt ccacccgtac
    11701 atcccatggc aatggtcaaa acggacttac cttccttttg gtaacttggc agaatcggct
    11761 caatcaaggc caataaatgt tgataaaagt cttctgactc aggatggttc atgacataat
    11821 cataaacagg ttcatccaca cccgtttggt ttctcagttc tggtagataa tagggatttg
    11881 gcaagaaacg gacatcaaag accaagtccg catcaatcgg gattccatac ttaaatccga
    11941 aagacatgac ttcgatacgg aaagactggg cttgttcttg gtctgaaaac tgctctgcaa
    12001 gggttttgcg cagctcacgt ggagtgagtt cagtcgtatc caccacattt tggctcatat
    12061 ttttcaaagg tgccaagagt tcacgttcca acttgattcc atctaaaata cgaccgtctg
    12121 ctgctagtgg gtgactccgt ctggtctcct tgtaacgagc gaccaattcc ttatcagccg
    12181 catccaaaaa gaggattttg aaatccaaac catcttgatt ttccaactca tccaaaacag
    12241 cttgaatctc tgaaaagaaa gaacggctac gcatatccac taccaaggcc aacttaggat
    12301 tgtcttcctt aatttcaacc agctgcaaaa acttaggcaa gagagctggc ggcatattat
    12361 caatggtgaa ataacctaga tcctcgaagg actgaatggc tacagttttc cctgcgccac
    12421 tcatccctgt cacaatcacc aagtgaagtt gtttctttgt catctttttc tccttatatc
    12481 aaaagaagtt tggcaacacc aaacttcaac tagcttatcc aatctctgcg atgacttcaa
    12541 tttcgacttt tacatcacga ggaagacgag ctacctccac agctgaacga gctgggaatt
    12601 cctctttgaa ggccgtttgg taaacctcat taaaaggaac aaagtcgttc atatcgctca
    12661 agaaacaagt tgttttgaca acatggtcaa agtctgttcc tgcttctacc aaaatagcac
    12721 cgatgttttt caagacttgc tctgtctgtt cttggatatt ctctcctaca atttccccag
    12781 tttcagggga taggggaact tgaccgctag caaacaaaag gttgccaacg atttttcctt
    12841 gaacataggg tccgatagcc tttggggcct tatctgtatg aattgttttt gccattttct
    12901 tttcctcaca atttttctaa gattgcatcc caagcctcat ccatccctgc cttgctgaca
    12961 gatgaaaaga ggatgaaatc gtcacttggg tcaaagttta atttcttttt gattgctgat
    13021 tcatgcttgt tccatttacc acgaggaatc ttgtccgcct tggtcgccac aatgatgact
    13081 ggaatctcat aatacttgag aaattcgtac atctgcacat catctgctga cgggtcatga
    13141 cgaaggtcaa ctagactgac aaccgcacgg agattttccc gagtcgttaa gtactcctca
    13201 atcatgcacc cccacttttc acgttccttt ttagaaacac gggcatagcc ataaccaggc
    13261 acatccacaa agcgcatctt gtcatcaatg ttaaaaaagt tcaggagctg ggttttacca
    13321 ggttttcctg atgtacgggc gagattctta cggttcaaca tagtgttgat aaagctggat
    13381 ttaccaacat ttgaacgccc tgctagggca atctctggca gttcatcctg cggatagtgg
    13441 gacttattag ctgcactgag caagatttca gcattgtgtg tattaagttc catagtcacc
    13501 tctaggctgt ttctaggatc ggtttatccg ttccatcgac agtttcttta gtgatgcgaa
    13561 ccaatttcac attttcctga ctcggcacct caaacataac atctagcatg gtttcttcga
    13621 tgatggagcg aagtccacgc gcccctgtct tccgttcgat tgctttatta gcaatctctt
    13681 gaagggcttc gtcgtcaaat tccaactcaa catcatcata agaaagcaag gtttggtatt
    13741 gtttcaccaa ggcatttctt ggctctttca agatgcgaac caagtcatca acggtcaatt
    13801 gctcaagagc cgcaaaaaca ggcaagcgtc caattaactc agggataata ccaaattttt
    13861 gaatgtcttc agcgatgatt tcttgcatgt atgagctgtt ttcgtcaatc gccttattgt
    13921 tttgaccaaa tccgatgact ttttcaccca gacgttgttt gacaatttct tcaataccat
    13981 caaaagcacc acccacgatg aagaggatat tttttgtatc cacttgaatc atctcttgtt
    14041 gtggatgttt gcgtccacct tgaggcggta cgctagcaac agttccctcg ataatcttga
    14101 gaagggcttg ttgcacccct tcaccagaaa catcacgtgt gatagacaca ttctcactct
    14161 tcttggcaat cttgtcaatt tcatccacat agataatgcc acgctctgca cgttcgatgt
    14221 taaagtcagc aacctgcaag agtttgagga gtatattttc cacatcctca cccacataac
    14281 cagcctccgt cagagctgtc gcatccgcaa tagcaaaagg tacattcaag ctcttagcca
    14341 aggtctgggc aaggaaagtt ttccctgaac cagttgggcc aatcatcaaa atgtttgact
    14401 tctgcaaatc cacatcttct gactcttcgc gtgtatcgtg gaaattgatg cgtttgtagt
    14461 ggttataaac cgccactgcc aaggcacgct tggcacgatc ttgaccaatt acatagtggt
    14521 tcaagatatg gaggagttca attggttttg gcacctcaga taagtctgcc aagacttcct
    14581 caaccaattc ttctcgaatg atttcctgag ctaactccac gcattcatta caaataaaag
    14641 cattgttgcc agcaattatt ttttgtactt cttcttggtt tttgccacaa aatgagcaat
    14701 aaaccatcat atcatttttt ctatttgtag acatgatttc cttccattct atactgtcat
    14761 tctatctaaa ataaggtcat gtaaaaagca tgaatactat tgaccagatt ggtaaaggca
    14821 tttaaccaaa ggaggataga aagcccgtaa cgctttttac gaaaagcctg tgctcctgcc
    14881 agaaagcaga tgaaacacag aaaagccgtg aatagaccaa ataaactccg ttccattaga
    14941 cttcctttct cttgcggtat tggatggtaa aatcataagg attcttctca tctttggcgt
    15001 aaaatttgct tgaaactgtc tcaaaaagag acaagtcaag ctcttcaggg aaataggtat
    15061 ctccttccac ccgagcatga atgtgagtca caatcacttc gtcaagatag ggttcaaaag
    15121 cctgaaaaat ctgctttcca ccaagaatat agagattctt ttcttgagcc tgataccagt
    15181 ccaagacaga ctggacatca tgaaaagtag caaccccatc tatcgtttct tctaggttac
    15241 gtgtcaaaat caaagtctcc cgttgtggaa gcaagcgacg ccctattcca tcaaaggtta
    15301 cccgccccat caagatagca tgattcagag ttgtttcttt gaagtgttgc agttctgctg
    15361 gtaaatgcca aggtagacga ttgtctttcc caatcacacc ctcttcatcc tgggcccaaa
    15421 tagctacgat tttcttagtc atgcttccat cctttttact gatagtacta ttctatcaaa
    15481 aaactcaaaa aaagactggt ttggaatagc ttacaaaata gaaaaaatct gtaagaaatt
    15541 tcctacagat ttatctatgt tgccttgttt cttacaaacc aggtgcttgt ccaagttctg
    15601 cggcaagcat ccaaactgtt ttctcaagtt cagccttagc accaacaaaa atatcgtttg
    15661 taacatcatc gccttcttca tcagtcacat ccaacgcttt ttggaaaaga gtgatgaggt
    15721 agcgataaat agctagaaca cgttccaagc tttcttcaac attacgatat tcaccagctt
    15781 cttcttcgat ttcactgttt tgaaggaatt ctgtcaatgt agagaatggg cttccaccga
    15841 gtgtaatcaa tcgttcgctg atttcatcta aatgaccatc aagagcatcc atgtactcat
    15901 ccatttttgg atgccatacc ataaaaccgc gtccacgcat ataccagtgt acttggtgca
    15961 aagcaacgtg agctacgtac aaatcagcta cagcttgatt caaaacttcc tttgtttttg
    16021 ccaatgctag tggcgctgct tttgttaatg ttgcgacatc ttttgctgct tcttttttca
    16081 attctaccat tttattttac ctcattcatt atttttatgt aaccacttct taatgattac
    16141 taccttagta tactactaag gaaaaccaat agcaagacaa agaacttata tgagaaaagt
    16201 tgcaatagac tgataattta agaattcttt agaagacaaa aaagagggtt ggatgcttat
    16261 agtcaatgga aatccatcag caaactagga aactaaaccc agcttgacca aagcacaagt
    16321 tttgaggtcg caggtaggac tgaccaagct gatgtggttt gaagaaattc cccaatacta
    16381 taatagattg aaataagatg aaaccaagtc gattaggaaa ggtaaatgaa tttctaaaat
    16441 gttttaccaa tcacaaggta tttgtctata ttcaatctac tatataagct tcatttccga
    16501 gcaagaactt gaatttactc gaggatgaac tatcataaaa caaagaaaaa gagggtgcta
    16561 ctatcacatc cctctttcaa atcatcgctt aataccaaac gctgacatct acgcgccctt
    16621 ggattccttt catgtattca gaagaggtat attgccaacc tttttttcct gaataatgag
    16681 ggttttccca ttctaaagca ttcgtatagg ccgctaccca gtttacatgt tttaaaatat
    16741 ctgggtgttt taaacgcgtc tgtaataaac tacgatagct atagacatac acattttgat
    16801 aacccgcctg cttcatcgtg tccatgtact tgttgatgat tttaacccaa gtgcctgtat
    16861 cacttggagc tctcttgctc ttatttacat attcccaatt ctcaacatca taatagatag
    16921 ggtaagacag gttcatattg tatttcttta taagttcaat ggtctgttta gcgtcactct
    16981 cagcatcggt ctcattttca gcataggtat agagatagac accataagga attcccagac
    17041 ggtttaactc cttaatgtta tgcgccaatt ccttgtcttc tttaccgcta taacctagac
    17101 gaacaatgac accatccact tcgttctcat caataacctt tttccaatca ttgatacgac
    17161 cattgtgctc actaatatca atgactttct tagcatgttc ggttcccact tgttcttctc
    17221 tattattaaa gaaatagcgc ttaccatctc tgtgaaccca gccgacattc aaatctttct
    17281 tttctttgag ctcaccagag gccgcaaaga tatagcgagt accatccata atcacttcgt
    17341 cagtcgccat ggcaccactt ccagtcaaat agtagttgcc ttgccactca ttccgagcca
    17401 tatagcccca cttcttgaaa tagtaccatt tgccgcccac tttttgccac tcttggttag
    17461 cataagttcc atcggatttt agataaaaat aagcagaata ggctggatca tagagccatt
    17521 cattttgcat catagctcct tgaccattca agaaataact tccttgccat tggcttttag
    17581 ccatgtaacc ccacttcttg aagtagtacc acttatttcc aatcaattgc cattcttgat
    17641 gagcataagc cccatctgac ttgagataaa accaactctt gtaattactg tcatagatcc
    17701 actcgttttg ggccatatat ccacctgatt tcaggtagta atttccatgc cattcattct
    17761 gcgagtaacg accatctgaa ttaatataaa accaagcctt atagtagttg tcaaaaatcc
    17821 attcactttg agctttagaa ccatcatcct ttacataata atccccatcc cagtgggcag
    17881 cagcattagt ctgtacttct gcgctcgttt gcgttttatt agaagactga ttttgctctg
    17941 aactacttga agctgtcgtt gtatcctgcg aagtttttgc tacttcagtt tcatttgcag
    18001 cgacatgact agttgccaag cctagtaaac agatacttgc taatccaatt tttgttttca
    18061 atctttctct cctataaaaa atgtaacaga catctgaatg ctgttccacc tagcttttgc
    18121 tacttactga ttattttaca aagtcaagca aagccaagaa gctttcagct tcaagtgacg
    18181 caccacctac aagggcaccg tcaacgtctg ggcaagccat gtatgaagca acattttcag
    18241 gtttaacaga accaccgtat tgaacacgaa ctttgtctgc gacttcttga ccaaagtcag
    18301 cagctacaac gtcacgaaca actttacaca ttttttgtgc atcgtcttgt gaagctgatt
    18361 taccagtacc gatagcccag attggctcat aagcgataac tgaggcagca acttgttcag
    18421 cagtcaatcc agccaatgca gcagatactt gagcacctac gaattcagca gctttaccag
    18481 cttcgtaagt ttcaagtgat tcaccacaac agatgattgg aagcataccg ttcgcaaaga
    18541 ttgcttttgc ttttttgttg atatcttcat cagtttcatg gaagtagtca cggcgttctg
    18601 agtgaccgat aacaacgtag tcagtaccga tttctttcaa aacttgtggg ctagtttcac
    18661 cagtgaaagc acctgcattt tcaaagtagc agttttgagc agcaacttta aggtttgagc
    18721 cttttgcaac agcaagaaca gttgtcaaat caagagctgg agcagcgata cctgcttcaa
    18781 caagatctga tgaaggaagt tttgatgcaa ctgcttcaac gaatgcttta gcttcttctg
    18841 gatttttgtt cattttccag ttaccagcga taaatggttt acgtgacatt tcacatacct
    18901 cttttttcaa tttattttct atttattcta tcacaattat acacagcttg caaatcttac
    18961 tcggatttca agcctacttg catggattaa tccttccaga gatccatggc atttatgaaa
    19021 tctgcagata cctgtgtcaa ctgaggattg cttgcttctc tttctgctct cttggcctca
    19081 atttgagcca cactcttgat tccttcatgg cgccagtttc tcaaaatcgc ctgaatgtac
    19141 ttccagtttg gttttccatt caaaacagct tcacgaagag cctccttaat caagtcagca
    19201 ctggttccat cttcctttag tgtcttggtc aaatcctcaa tctcaaaagg cgtcaacaat
    19261 cgtcccaact cctgctggaa ggtttccacc aaatccttga gctggttttg aggtgttagc
    19321 tggtctgaac ttgaatgaac tgctccaaac aggtcatcca aacgttccaa ggccaaacta
    19381 gcatcaaaga gcaattcaat ttcgccattt aattcgatag tacgatactg gagcagtccc
    19441 ctttccgtca gattagaaat ggactggttg acatccgaaa tttccttgcc aatcctttca
    19501 gcaatctggc ttggcgacat ttcttctaag cctgtcgtat tttgcaaata gaaaaattgc
    19561 caaaccagaa aatcgtcgct agaaggaaag agttccttaa aatgcaagag cagggcactc
    19621 ggtaaaacca aggcacctga tttaaaagcg tctaaatatg tcataattcc tcttataaat
    19681 acccatatgc agatgcatca tcttctatct ttctccagtc aaaaggcgtc tcctgataga
    19741 ccgcatggtt tacccaatta ctgaaaaaga gggctgcaga tgaagaccaa caaagacaag
    19801 gtacctgatt aacatcatca tctttaaagt aattttctgg aatatgtggg tcgaaacctg
    19861 catcacgatc tcgaaaatac tcttttgcca aggtatcacg gtcatactcc aaatgaccaa
    19921 aactataaat ttctcgtaaa tcacgactgg ccaaaataga aaccccaacc tgaggtcctt
    19981 ctgataaaat ctcgagattg gtcttgttta agacctcttc cttagaaatc tccgtgtgcc
    20041 gtgaatgagg ggatacatag ctatcatcaa agcctctaaa tagaaggtga ccctctttta
    20101 gggtgtcctg aggataaata cctgatagct tactgtccat ctggtatttt tctacaccat
    20161 agcgcagata aagcccagcc tgagcccccc aacagatatg aagggtcgaa tagacatgag
    20221 tcttagacca ctcaagcatc tgtctaaatt cctcccaata gtccacttcc tcaaatggta
    20281 aatgctcaac tggagcaccc gtgatgatca tcccatcaaa atactcatcc ttgacttcag
    20341 gaaaagtttt atagaaggtc tccatgtgct ctgaacgagt tgttttagaa cggtggctct
    20401 ccatatagag aaaatcaata tccagttgta ggggtgtatt agccaagtgg cgcaacaact
    20461 gggtctctgt gaccattttc tgtggcatga gatttaaaat taaaatcttc aaaggacgga
    20521 tatcttggtg ggcagcacgt tgatcatcca tgacaaagat attctctgtc cgtaaaatct
    20581 caacagctgg caatttttta tcaattcgaa tcggcataac cctctcctaa ctgtactctt
    20641 tcaggaataa ttgcatatgt ttgaagacaa atctcaaaca cttagtcctt ttattatact
    20701 gcaagaagat atagttttca attatagttt ttctctaact agttatagtc tatttttata
    20761 tcctagtgta gagaaaacag ccctagggac tgttttcatt aataatgcat aagaactttg
    20821 tagtcgtagt caccaatttt ttcacggccg ttcaattcat ccaattcaac aaggaaggca
    20881 caacctgcca taacaccacc aagtttttca atcatctcga tagttgcctt aacagttcca
    20941 cctgtcgcca aaaggtcatc tacaataaga acacgttgac ctggcttaat ggcatccgcg
    21001 tgcatagtca aggtatcgac accgtactct ttttcatagt cagcagaaat aacttcgcgt
    21061 ggcaatttac ctggcttacg aacaggcgca aaaccaattc ccaactcaaa ggcaactgga
    21121 caacccacga taaatccacg agcttcaggt cccacgatca tgtcgacttt cttgtcagta
    21181 gcatactgaa cgatttcacg aacagcgtag ctataagcat ttccatcagc catcaaagga
    21241 ctaatatcac ggaaggtaat gccttccttt ggataatttt caattgttgc aatgtaatct
    21301 tttaaattca tcttttttct ttctttcaaa gttttttact ctctattata gcatattttt
    21361 taagaaagaa aaaaggaaaa gttaacttca ataattatct aacgttttga cgatttataa
    21421 ctagccatcg caataaagcc caatttctgt ttattcttag caaacatttt atacatagtt
    21481 aaaaactgct ttctattctc ctttttacaa gcatttacac aaattttcaa agttcctagc
    21541 aaaccttcgt cataaatcat acccgataat ttcattaatg tcatttcacc agtcaatgct
    21601 ttcacatcac aataacctga ttctatcatc acctgttccc aaccatcttg agttaaagga
    21661 cctacattta catgaattgc ttgtgataat tcctgtctga tagactcttt agcttcctta
    21721 agaagcacat catgtgtcaa gagaagacct ccaggtttta atacccttag atattccatt
    21781 acacattttt tcttagcttg atcggcttgc atagtcagca tagcttcatt tataacaata
    21841 tcaaaactag catcttgata aggaagtttc attgcatttg ctctttcaaa actgattaaa
    21901 tgagcaacac ctgccgttcc agcagatttt ttagccactt ctaaagcttg agcatccata
    21961 tcaacagcag ttatcttgca accaaaacgc tgtgccaact caattgctgt agttccccta
    22021 ttacacgcaa cctctagtat tctcttttct tttgaaaatc ctccttctgc aattaaccaa
    22081 tctgtggcac gctttccacc tggacgtaag cgttttttcc ccaattttgc taaaaactta
    22141 tgacctgctt ctgacatttg aacacctctg ttttttcttc attataacac aaaatgatat
    22201 tatctgacaa ttctaatcta ttatttgata aactagaatc aaaagcatac aagtcaccat
    22261 aactatagca taaatttatt attacctctc tagttcgaat tcaattgctc acgtagttta
    22321 cgcatatagc ttcacttgta gatggtaccc acaaataata ctcaatggaa atcaaagagc
    22381 aaactaggaa actagccgta agctgctcaa agtacagctt tgaggttgca gataaaactg
    22441 acgaagtcag taatcatacg tacggcaagg cgacgttgac gtggtttgaa gagattttcg
    22501 aagagtatta aagagcatca caatatagat gcataatatg acttccctag caaaaaggag
    22561 agaagcattt tgtttctctc cctagatcaa ctgatatctc tccactacaa ttgataaaga
    22621 gatatctttt cttgtagtgc tttgaatttt atttatttta gtagattgtt ttttcagttt
    22681 ctacatcgaa gaagtgtgct ttgttcaagt caaatccaag ctcaactgtt gcacctgttt
    22741 gcaagtagtc acgagcatca acttttgcaa caaactcgtc tttaccaact tggcagtaaa
    22801 ggtgagattc tgaaccaagc agttctgata cagagatagt cgcttttaca acacagtctg
    22861 ggaatgtttc aaggaaagca ggttctgcat tcacgtcttc tggacggata ccaaagatca
    22921 attcttttcc ttcgtagcct ttttcacgaa gaactttcaa tgctccttct ggcactttca
    22981 aacggaaacc gtcagaaaca atttcgctac caaccaattt cacgttgatg aagttcatag
    23041 ctgggcttcc gatgaatcct gcaacgaatt tgttaactgg atttttgtaa acttcttgag
    23101 gagtaccgat ttgttctaca cgtccgatag tacctgtacc agcagggttc ttagtagctg
    23161 acataataac gatacggtct gcaagtgtca tcgcttctgt ttggtcgtga gttacataga
    23221 tagttgtagc tccgatacga cggtgaattt tagcgatttc agcacgcatt gatacacgaa
    23281 gtttggcatc caagtttgac aaaggttcgt ccatcaagaa tactttcgca tcacggacaa
    23341 tcgcacgccc catggcaaca cgttgacgtt gaccacctga aaggtcagcc ggtttacgtt
    23401 ccaagaattc tttcaatcca agtatttcag ctgcttcttg aacacgtttg ttaatgtctt
    23461 ctttgctgta tttacgcaat ttcaaaccga aagccatgtt gtcataaaca gtcatgtgtg
    23521 ggtaaagagc gtagttttgg aataccatgg cgatatcacg gtcttttgga gctacgtcgt
    23581 tgacaaccac gccatcgata gatgcagtac cttctgtgat gtcttcaaga ccagcaatca
    23641 tacggagtgt agttgattta ccacatcctg aaggtcctac gaaaacgata aattctttat
    23701 ctttgatgtt caagttgaaa tcttcaactg aatagtgttc gctgtttgga tattttttgt
    23761 aaatattttt aagattcaat tctaccatga ggtgaactcc ttttgtcttt tgataattat
    23821 attatagatg aaaacgcttt atatttctat ggcaagatga ccaaaaaaat aaaaaagttc
    23881 tgtgcaactt gcacaaaact ttagagaata tcggagaatt tgaagaagat aatctttatt
    23941 attcttctat gacaaaagca gaaacaagga tcagttttcc catattttcg ctgattctcc
    24001 actacatttg actggatt
//
LOCUS       DAVMAH010000035        22181 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVMAH010000035 DAVMAH010000000
VERSION     DAVMAH010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22181
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.035"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(380..2350)
                     /gene="tkt"
                     /locus_tag="VYO94_001336"
     CDS             complement(380..2350)
                     /gene="tkt"
                     /locus_tag="VYO94_001336"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1759970.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYNDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            complement(2387..3082)
                     /locus_tag="VYO94_001337"
     CDS             complement(2387..3082)
                     /locus_tag="VYO94_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1759971.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            complement(3093..4177)
                     /locus_tag="VYO94_001338"
                     /pseudo
     CDS             complement(3093..4177)
                     /locus_tag="VYO94_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(4203..4514)
                     /locus_tag="VYO94_001339"
     CDS             complement(4203..4514)
                     /locus_tag="VYO94_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEV1759972.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            complement(4542..4991)
                     /locus_tag="VYO94_001340"
     CDS             complement(4542..4991)
                     /locus_tag="VYO94_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1759973.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            complement(4969..5397)
                     /locus_tag="VYO94_001341"
     CDS             complement(4969..5397)
                     /locus_tag="VYO94_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1759974.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKPPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSGIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            complement(5390..6853)
                     /locus_tag="VYO94_001342"
     CDS             complement(5390..6853)
                     /locus_tag="VYO94_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV1759975.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKG
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKLTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFSELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSAFLTEGDKQRLQAKIQEINYE"
     gene            complement(7382..9718)
                     /locus_tag="VYO94_001343"
     CDS             complement(7382..9718)
                     /locus_tag="VYO94_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV1759976.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMIVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            9851..10600
                     /locus_tag="VYO94_001344"
     CDS             9851..10600
                     /locus_tag="VYO94_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV1759977.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            complement(10892..11506)
                     /locus_tag="VYO94_001345"
     CDS             complement(10892..11506)
                     /locus_tag="VYO94_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV1759978.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(12321..12590)
                     /gene="rpsO"
                     /locus_tag="VYO94_001346"
     CDS             complement(12321..12590)
                     /gene="rpsO"
                     /locus_tag="VYO94_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV1759979.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            complement(12731..13360)
                     /locus_tag="VYO94_001347"
     CDS             complement(12731..13360)
                     /locus_tag="VYO94_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1759980.1"
                     /translation="MKLAVIAANGQAGKAIVEEVVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            13599..13799
                     /locus_tag="VYO94_001348"
     CDS             13599..13799
                     /locus_tag="VYO94_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1759981.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIISLLYSYRFRFSL"
     gene            14230..14370
                     /locus_tag="VYO94_001349"
     CDS             14230..14370
                     /locus_tag="VYO94_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV1759982.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            14377..14553
                     /locus_tag="VYO94_001350"
     CDS             14377..14553
                     /locus_tag="VYO94_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV1759983.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTWK"
     gene            14611..16554
                     /gene="thrS"
                     /locus_tag="VYO94_001351"
     CDS             14611..16554
                     /gene="thrS"
                     /locus_tag="VYO94_001351"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV1759984.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(16603..17577)
                     /locus_tag="VYO94_001352"
     CDS             complement(16603..17577)
                     /locus_tag="VYO94_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1759985.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(17570..18247)
                     /locus_tag="VYO94_001353"
     CDS             complement(17570..18247)
                     /locus_tag="VYO94_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1759986.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            18403..19476
                     /locus_tag="VYO94_001354"
     CDS             18403..19476
                     /locus_tag="VYO94_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV1759987.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVTTVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     EKETLGRLTQLLIDTRYQVWKNR"
     gene            complement(19567..19870)
                     /locus_tag="VYO94_001355"
                     /pseudo
     CDS             complement(19567..19870)
                     /locus_tag="VYO94_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(19939..20376)
                     /locus_tag="VYO94_001356"
     CDS             complement(19939..20376)
                     /locus_tag="VYO94_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV1759988.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            complement(20452..21294)
                     /locus_tag="VYO94_001357"
     CDS             complement(20452..21294)
                     /locus_tag="VYO94_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1759989.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            21406..22056
                     /locus_tag="VYO94_001358"
     CDS             21406..22056
                     /locus_tag="VYO94_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV1759990.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
BASE COUNT         6822 a         4989 c         4002 g         6368 t
ORIGIN      
        1 ttaatttcat aataaaacac cccaaaaagt tagatttttt ctgtctaact tttggggtca
       61 gttcatttta acatcctata ctatgcgttt tttaatttta gagaccttct ctctagcttt
      121 caaaaaactt acaatatcct aagtcaatct gtggatgctg tgtttattga ttaaagaaac
      181 tatctagatc agtagcaaag tgattagcgt acttcgcaac cgtttcaggg tatactctat
      241 tgtgtatact atctactata actttcgtag ataaattatt acattctcat tatagttttt
      301 aaataaccaa tcatctgatt agtgtctatc actacatctg ctagtctgac aacagctgta
      361 tcttcattgt aattggtttc tatagggact taacttgagc aacgatattc tctaccgtaa
      421 atccataatt atcaatcaca gtctgagctg gggcagacgc accgaagatg tcaataccaa
      481 tgaccgcgcc atccaaacca acatacttgt accaactttg ggtcgctgcc atttcaatgg
      541 ccacacgacg acgagtctta gatggtaaaa tgtcttcctt gtaggtagca tcttgagcat
      601 caaatagttc ggttgagggc atagatacca cacgtacttt accaccttgt aaaaccaatt
      661 ccttagcagc tttgatagct agattgacct cagatcctgt agcaatgata atagtatcaa
      721 atcccggggt atcatacacg acgtaggctc ctttagcgac cttaccaaag tctgtccctt
      781 cttcaactac caagttttga cgggttaaga caatgacagt tggagtggtg gtactggtca
      841 aggcatgatg ccaagccgct tgagtttcac gggcatccgc tggacggata acagtcaagt
      901 ttggcattga gcgtaaacct gccaaatgtt caactggttc atgagttgga ccatcttcac
      961 caacggcaat tgaatcatgg gtaaagacat aagttacagg caactcctga atggctgata
     1021 gccgaatagc agctttgacg tagtcagaga aaacaaagaa ggttccgcca taaactcgta
     1081 aaccaccatg aagagccatt ccattgagga ttgttcccat ggcaaattca cgtaccccaa
     1141 actgaatatt gcggtttaat ggattatatt tatcttgtaa gccatctgcc ttgatgtagg
     1201 tcatgttgga gtgagctaag tctgccgatc cacctaagaa ggttggtaaa actgctgctg
     1261 ctgtattaat agcatcttgg gacgaattac gagttgcttg agagaagcca ttctcataga
     1321 cagggaagtc tttttcagta atggttacag gggattttcc agctacaata gcgtcaatct
     1381 cactagcaac ttcgggataa gcaaccttgt aatcagacac caaactagcc caagcatcgt
     1441 atgcctcctg accacgatcc gctacatttg tcttgaaatc agaatatact tcctctggta
     1501 cttcaaatgg atcgtaatcc catcccaaaa acttacgagt tgctcctgtt tcttctgctc
     1561 ctagtggtgc accatgaaca gcatttgtac cacttttatt gggtgagccg taaccaatta
     1621 ccgttttcac ttcaatcaaa ctcggcttac cagaaaactt ggccgtctca attgctgtag
     1681 aaattgctgc taaatctgtt ccatcttcta ccagaactgt atgccaacca taagcatcgt
     1741 aacgggcgcg aacattttca gagaaagtat ctttggtctc accatccaag cagatgtcgt
     1801 tggagtcgta gaggacgata agcttatcta aagcttgatg acctgcataa gaagccgcct
     1861 ccgcagacac tccttccatg aagtcaccgt ctccagcgat aacataagta taatggtcaa
     1921 aaatagggaa accatctttg ttgtacttag cagctaaaaa acgctctgct tgggcgaaac
     1981 caacggcagt agaaatcccc tgaccaagcg gaccagatgt cgcatccaca ccagacgtat
     2041 gcgtcacttc aggatgacca ggtgtcttag atccccattg ccggaaattt ttaatctcgt
     2101 ccatggatac atcgttatac cctgttaaat gcaagagagc atacagtagc attgatccat
     2161 gacccgcaga caagataaag cgatctcggt taatccagtt tggctgctca ggtgtaattc
     2221 taaggtgctt tgtaaatagg ctataagcca ttggcgcagc acccatgacg attcccgggt
     2281 gaccagaatt agatttgtta atagcatcta cgccaagaaa acgaatggcg ttaactgatt
     2341 gtagtgacat atattcctcc taactaataa atttcttctc aaaccattat ttgattggca
     2401 ttgtttttcc ggtcatttct tcgtaatctc tagaacagat atcccaggct ttggcaatat
     2461 cgtcatccaa accaaataat ccactgcgac ctataacata aatatctggt cctgccacat
     2521 caatttgttt gaaagtctta cgactcgaag aaccatccat ctcaatgatg tagtgataac
     2581 cattctgaac tctaagctga cggagttctt ggattttata caaggtagac tccaaaaagc
     2641 gttgtcctgc aaaacctgga tctacagtca taatagttac tttgtcaagt aaatcaatgt
     2701 agggaaagat tgtagaaaca ggtgtttcag gattaaggac aacaccagcc tttagacctg
     2761 catcatgaat tttatcaatc aaacgaaaag caagaccatt cagaacttca gcatgaatac
     2821 aaatatactc acattgtaaa tcgagaactt gatctaccca aaaggttggg tctgtgacca
     2881 tcagatgaac tgataaaggt gtgtcactaa ttttttgaac ttcttgaatg aaccaaggag
     2941 acaaggtaat attgggaaca aaatggccat ccataatatc gatatgataa gatgctactt
     3001 tatcattcaa aaaagtaatc tgctctttga atttgtccaa atccatggtc atcaaagatg
     3061 gtgaaaattc aattcttgac atcgttaccc tcttacaaaa tttcaatatc tgacaaatca
     3121 atctcttctt caacagtcat aactggttct gtatgtttta ttggtttttt caaaatcgcg
     3181 tagacaagtc ctgtgactac aatgttggct aacaaagcac aaataccagc tactggacga
     3241 gtcatggttg gtaacataag cactccacca aatggcacgg cagaatcagc acccattgtc
     3301 aaagaaacag caccaccaac agcaccaccg atacctgttg caatgagacc tggaaccaag
     3361 ttattcataa caatcggaat tacaccttca acaatattga caatccccat aggaacagcc
     3421 gatttcaatg tttcgatttc ctcttgagta tagatatttt tttgagtaat ttcgcgataa
     3481 aataggccaa tccaaatcca actggtgtag cagtattcac caattgcaaa gcagtcaatg
     3541 gttctttcac accttcagcc tgtaaagtca acacaaaggc atagactgtt ttattaagtg
     3601 ggccaccaaa gtcaacagca ctgagaactc caataactgc ccccatcaaa ccatttgaag
     3661 cacttcccaa gctttgtaat aagctcgtca accagttggt aaaggctgcg ataggcgctc
     3721 caataatata aatcataatc aaactactta ccaaagaggc tacaaaagga ataatcaagg
     3781 ttggcattaa acctttaatc cagtttggta ctttgacctt tttaataatc gcttgaacca
     3841 agaaaccagc tatataacct cccaagatac caccgataaa ccctgaacca acagaattgg
     3901 caattagacc aacaacaaaa cctggtgcaa tccctggctt accagcaatc gagtaagaca
     3961 aacctgtagc aataacaact ggcaagagac caagggcttt accacccata gttgctaaag
     4021 catcccagat agtgaatttt cctgctacaa gagcgtcagg aacaccaccc cccattgcta
     4081 aaccaatggc aactaagaat cctgcaccac aaacaattgg aatcatatag gaaatggctg
     4141 tcaataagtg accttttaag tttaagtgtt tcaacatata ttttctcctt aaatattttc
     4201 agttatttcg taacaatctc aacagcttta gcaatcagtt tattgggaga tttgactgcc
     4261 acttctgttg gaaccttgat aatcttttta ccctcaaagc gttccatacc agaaatctta
     4321 acatcaactg ctaaaataac tacatccgct gcatcaatct gctcttgact caattcattt
     4381 tctaccccta ttgtcccctg agtctcaaca tgaatcacat gtccagctac ctttgcggca
     4441 ttctctaatt tttcctgtgc aatataagtg tgggcaattc ccacagtaca agctgcaaca
     4501 ccaacaattt tcatacggat accctccaaa attttttctt attaacaaaa agctgcaatc
     4561 acatcatcag atgtctgagc ccgaactaat ttggcaacaa cttcgtcatt accaagtttt
     4621 cgagcaaaga gtgataaggt cttcaaatgc tccctagcag cttctgtatc atcaccaact
     4681 gcaaagagta caattacttt gacccctttc ccatcaatgg tctcccaagg aatctcattg
     4741 tgatttatag ctatgactac ccccgccttc tccacagcag aactcttgct atggggaata
     4801 gcaatataat tcccaatacc ggtctgtcct tctgcctctc tctgataaag accttcgata
     4861 aattggtctc tatcagacac ataacccgtc tcaaccaata gttgagctaa tgcctcaaaa
     4921 acctcttctt tgctctgcat ctgtaaatcc gtctggatca gactcacatt aagaatatct
     4981 ttgatttcca tatattatct cccgtaattc ttcttttgtt aactgtttta attgatttat
     5041 gaatgattca tctgctagtc ttctcatcaa tgttttaata cctgacttgt cctgtgatac
     5101 tgcaatggcc aaaccgataa taaggtcaac acactggata tccttcgacc attctctgat
     5161 aggtggtttt aatctagtaa tcactaagac atgatgttga aagtttcctt cacaatgtgg
     5221 tagaagaaca cctttagcaa cctctatact tccctgtctc tcacggtaat atagaagctc
     5281 ttctattttt tctgtatctt cagaaacaag aaggctgatt tgatttgcta attctttgta
     5341 ggcttcttga cgattttgaa cagatatatc cataaggaca agcgaaagat tattcatagt
     5401 ttatctcctg aatttttgct tgaagacgtt gtttatcacc ctcggttaga aaagcactaa
     5461 ctaggacaaa cgggacactt gctggttcct gcaaagctac cgtcgtcaca atgaaatcta
     5521 aatctggata tagatttatc agctcatcta attgatgata agcaactaca tcaataatat
     5581 ccaattcaga aaattgcttt tctaatcgtg ctcgtaaaag ctctgaagtt ccgacacctg
     5641 atgtacacat cactactgtt tttagaggac gtgctcgctt ttcttgaaac cgtgcaaaat
     5701 ataagactag aaaaccaatc tcgtccagac tcaaggacgc aaaaccaaat actagactca
     5761 cttctttaga aatagttgtt aactctttaa ccagattagg ataggttaaa agaatttgtg
     5821 ataaaagact attcttaatc tgtactctat tatctaatct cctcagtaag ggactgatat
     5881 gactcgccaa gtcaacaaag tcaggatctg tcgtttcaat ctctctattg tccatacaca
     5941 tacggctaaa atagtaatga gtgacatcta aaactcgctg agaaaaagga agcttcccgg
     6001 aagaaaatgg tttttgcaat ctcgaagata caacgtattg ataaagatag tcaatctcaa
     6061 ctgcatcaac cttcatctta aaatattgtt caatttcttg aataattttt tgacagacac
     6121 tgtaaatttt ctcatcaaca atagtaagtt ttgaaggtgc tacaacatga atactagtac
     6181 tacgacgatt cctactgata aaaatataca ggtgagagaa aatatttata ttatatggat
     6241 agggaatgtt tacccccaat tctctctcaa gtgtaatcag taatcccaaa caaaagtgag
     6301 caagttctcc gtcaagaggc tgaaccttat tctgtgtaat ttgctctaaa tccaactgat
     6361 taaacattgg cagtagattt agaatggctg aacgaatttg agcctcatcc ccatcaataa
     6421 aaagctttcg ttgtctcatt tttaaatcta acccataaat tgctagactc tcttgtaata
     6481 tctgacgatc ttttagtact actgactcgc ttacgtagaa ttcctctcct aaatcataaa
     6541 tagaatgtgg cttaggagca gtcaacaaga gacgttctag taatttttca cgccttactt
     6601 caggatcaaa agcctctgta aaattcccat caacgtccac gagggaactt cttggattta
     6661 atttgaagcc tctgcctttt tcagataaaa tgaatgcttc taccggacaa tctttgttga
     6721 ttcccttgac aaggcgataa accgttttat cagagcaatt taatttttct cccaatactt
     6781 tagcagatat ataatcctta ctatctcgca aaaggagcaa caacgtttcc atttgttctt
     6841 gttttctaga cacgatacac ctcctttatg attccattat atcgctttca aaaaataata
     6901 tacttcgcat tttgtccttt gcaatggaca tttttgtttt tatcaaaaat atgatatcaa
     6961 atagaacaga acctcactat gccaaaatca ttttaccttt tcttcataac atctatttta
     7021 gttgaaatat ttaagttgct tttcgtattt gataagaaat aaaccaaacg attttctaat
     7081 aaataacact atgttccatt taacaataga tagcatcttc attttcaaac taccaaccta
     7141 tccgaccatt tgttctagca atagaagaga gttaaaatta cttcaatctg tcgctttctc
     7201 tttcttacat caaacttcaa atagtctaac tacagatatt taaatctatt acctcaatcc
     7261 aagcaggctt gagaatcact cttgggttca ccgatagata atagacatgt aggccttgca
     7321 catcagatct acgatagatc catcgtataa aaaactgcaa tccacagatt gcagtctttc
     7381 tttattttct agcttgatag cgactagtca ggatgaaaat cactgtaaag accaacatca
     7441 tgacaccata aacaggcaac gtttgttctg tcaaggttga aatttcaagc agtttttgga
     7501 ttcttgggaa gagagctgtg gctaggaagc ctcctactga ccagacaatc aagaggactc
     7561 gccatagagt gaatggcatg caggctctaa atacggataa gaaaccaatt gaccccaaga
     7621 gataatagag gagagttgag atttctaact cagaccaacc ttgactcgtt ccaaagattt
     7681 tcacaaaaag aacgctaaac acgatcatga gggcacttgg tagggcacga agcatggatt
     7741 ttctgaggaa atttggctca acaggtttga tatttcgctc aaaagtcaga acgaatggtg
     7801 ggaaaccttc cacaaactgg tcaatcatgg taatctggat cggaatgaag gggaaaatca
     7861 aaatccactc tgaccgacct agtaaagcac tggcaataca gatgactgct aacaggaagg
     7921 aatagatggt ctttatcaag aaaatcgggg cgatgtgggc aatgttattg accacgcgac
     7981 gaccctcgaa gagaatctca ggaacatcat taaagtctga gttcaagaga accagattgg
     8041 caatctgacg ggttgctgga tccccctccg ccatcacgat agaacaatcc gcctcacgaa
     8101 gggccaagat atcattaacc ccgtcccctg tcatagccgt tgtatgaccc gcttttttca
     8161 acgtttggat gatgagtttc ttttgatgag gggaaacacg tccgaaaata gctgtctcct
     8221 ccgccatggc catcaattcc tcatcggtga tttttgagca atctacatag ctgtgatagt
     8281 ccgcaaaacc agccttctgg gcaatgctgg acaccgtaac tggattgtca ccagagataa
     8341 tcttgagtcc cacctcctga gaacggagat agtccagcgt ctctgctgct ccctctcgaa
     8401 tggggtccaa gatttccagc aaggctagag cctgaatatc agatggtttc tgtggtttgt
     8461 gatggtctaa tttctcctga ctgagagcta agaccaagac acgtgatcct ctctccaagg
     8521 cctccctggc ttctgggact tcagaatcca gcaacatctc aggtgcccct aagaaaactg
     8581 tccccaagcc ttctaactcc atagcccccc acttgcggtc gctcgagaag ggaagattgg
     8641 aaatcatagg ataagcaaca tctcccacaa aacgctggcg aatggcttgg gcagttggat
     8701 tcttatcctc actatgggcc atgtagctag tcaagatgct ggcaatagcc tcttcaccgt
     8761 aagtttccgt cagtggaaga acagcctcca cctgcatctt tccttgggtg atggtgcccg
     8821 tcttgtccag acagagcata tccacgcgcg ccaaggtctc aacagagtac atctcctgca
     8881 ccaagacctt tttcaagccc aacttaatca ctgcagtcaa gagcgaagta atggtcaaaa
     8941 gggcaattcc cttaggcaac attcccaaaa gagctgtcga cgagtttaca acggatgact
     9001 tgagaggcag gccttttaaa agcaaggctt ccagcaagag agccagacca aagggaatga
     9061 taatcttccc agtaaaacca gccaacttgt ccagcgattt catgatacgg gagttgatgg
     9121 gtttaacggt cttagcctca agcatgagtt tggcagcata gttgtctgca ccgacatggt
     9181 gaacttgaga taaaactgac ccactggcta ggaaacttcc tgacaaaagt aagccgtcaa
     9241 cttccttttg caccaaatca ctttctcccg ttaacatggc ttcattgact tccgcaaagc
     9301 cttccaaaac caaggcatca ctaggaatct gctctcctgc agacaaacga atgacatctc
     9361 ctagcactaa ttcttcagga ttaagagcaa cttcctgacc atcacggatg gttttgacct
     9421 tttccttggt catgagattg agcttgtcca ccatgtgttt ggctcgtagc tcggtcacaa
     9481 tcccagaaaa agcgttaaag cagataacag caaagaagac cagattgctc caagcctgca
     9541 caaaggcaag ggccaaagca atggcaaagt tcaaagcgtt aaaaagggta aagacatttc
     9601 gtttaacgat ttgccaagtg ctggtactgg ctgatgcggt aaagtcattg accaaaccct
     9661 cagcctgtct ttccttgact tctctttggg ttaatcccat aatcttattt ttatccataa
     9721 attctattat atcatttttt ttaacagaat tctaatttca tcccaaatat gcatctagtc
     9781 aagggaaaag tttgccagcc ctcctttgat aaggtataat aataacaaga aaacaatcga
     9841 aggagatcgc atgttttata cttatttgcg tggattagtt gtgttgctct tatggtccat
     9901 caatggcaat gctcactatc ataatactga taaaattcct aatcaagatg aaaattatat
     9961 tttagttgcg cctcaccgta cctggtggga tcctgtttat atggcctttg cgaccaagcc
    10021 aaaacagttc atttttatgg caaaaaaaga actctttacc aaccgtatct ttggttggtg
    10081 gattcgtatg tgtggcgcct ttcccatcga ccgtgaaaat cccagcgcct cagccatcaa
    10141 atatcctatc aacgttctca aaaaaagtga ccgctctctc atcatgtttc caagtggtag
    10201 ccgccactca aacgatgtca aggggggcgc agcactgatt gccaaaatgg ccaaggtccg
    10261 tatcatgccg gttacctaca ccggtcccat gactttgaag ggcttgatta gccgtgaacg
    10321 tgtcgatatg aactttggaa atccaatcga tatctcagat atcaagaaaa tgaatgatga
    10381 aggcattgaa acagtcgcca atcgtattca aacagaattc caacgtctgg acgaagaaac
    10441 gaaacaatgg cacaatgata aaaaaccaaa tccactctgg tggtttatcc gcatccctgc
    10501 cctcatcctt gctattatcc tcgctatcct aaccatcatc tttagcttta tcgcaagctt
    10561 catctggaac ccagataaga aaagagaaga acttgcatag aagaaatgaa ccttggccaa
    10621 acagctaagg ttttcattta tatagtagat tggaactaga atagtacacc tctacttcta
    10681 aaacattttt agaaatcgat ttgactgtcc tgatcgattt gtcctattct tatttcattt
    10741 tactatattt ataagaatct cctaatcaaa tcaaaagcca ctctacaata gagtaacttt
    10801 aagattgtcc atttatactc aatgaaaaag ccctctgaaa atcagagagc tgatttgagc
    10861 tcgggctaaa atcctagtga aacaaaaaaa tctacacgat cagaaaagtc tctatcgtac
    10921 cattttcata catgatgtat agtccaagta gaatgaatac taagggcaca atgattcgct
    10981 cgtatttttc aattgtctcg aatattaacg gaatagagga taacacccta ctaatctcgc
    11041 aaaagataat tatgccgatt acaaacacaa gcaaggccac gagggtctgt gaccaatcta
    11101 acgaagcaaa ataaggtata tagataccta aattatctcc gccagacgca attgtcagca
    11161 atgtaactgt ccaaaacagt tgatttgcct tgctttgttc taatctttca ataatttctt
    11221 cctcttcttc ttccgcatct tctccaacaa ttgcaaagcg aatccctaaa tagataggga
    11281 ttaaaccaag caatccaacc atccattctt caggcacgaa attaacgaca taagcagcaa
    11341 ctaaactcgc ccctacaagt aagcctgtgc ctagatattg ccccgcataa atatgccatt
    11401 tctgtttatt ctgtgatagc tgtgcaaata aaataattaa aataattaaa taatcgatac
    11461 tggtggaaat ataaacacca atagcagata tgattgtctg tcccataaaa aaaacctcct
    11521 gtattagtca gtaataaatc agcagatttt aggagagcac agacacatta atttagctat
    11581 cgctagtggg taatatcgaa cgtaggaaag cattttactc ctcctcaaaa cgtagttaca
    11641 aagtaatttc taactggaat tcagtgacta cttccatgta aagtataaca tactatactt
    11701 tactttgtaa agagtgggct cttctagggg gcttgcatac agctactcgg cttgaaaagc
    11761 cgagtaactg cgcaccttta tggtgtaatt agctgatacc atttgaggtt tttgtagtct
    11821 ccaaaattgt taccgataaa acctcaataa aaaagccctc tgaagtcaga gagctgattt
    11881 gagcccgggc taaaatccta gtgaaaaaga tgaaactcct tgtgctcatc gaacactgtg
    11941 tcatttccct attttcatac ggatttttga cgcccttagc atcatgattc ttgctagata
    12001 aatcgtttat agactaggcg acgaggcgaa gatcgtacga aactttcagt gaaacaaaaa
    12061 aatctccccg aagggagaaa agctggttta ttttacctta cagtgctagg aaccgtaacc
    12121 gaagactata cttgagtata gcgaggtaag gtgacaacgc aacaaagcta cccaatttag
    12181 agtagcttca ttatcaagat atgctcaatt gaacacggcc taagcacttg gcaaaaaaga
    12241 taaaatctcc tagaaactga agtttcttcg tcaattttcc tatttttgct ttgtgctttt
    12301 gacagcattt gtatcttgaa ttagcgacga agtcctagag agttgatcaa ctcacggtaa
    12361 cggttaacgt cgtttttacg caagtatgca agcaagttac gacggcgacc gatttttttc
    12421 atcaatccac ggtaagtagc gtggtctttt ttgtgttgtt tgatgtgttc gttaaggtgg
    12481 ttgatttccc aagtaaggac agcaacttga acctctactg aacctgtatc accttcgtga
    12541 cgtgcatatt gtgcgatgat ttcatttttt ttctcttttg agattgccat gatgtttctc
    12601 ctttttattt ggcttcatcc gagtgacagg ttggcatgcc tgtaaccaag aagaagttat
    12661 ttgtctttac gacaatccct attttaccaa gatttaaatt ttctgtcaaa cattaatact
    12721 ctcatagtta ttatttttca agtaaagaga tacgttcttt tatatgatga cctttttcaa
    12781 gttcatctac caatccaata gcataatctg cataactaat ctggcttatt cctttttcat
    12841 tagtagtaaa aatttctcct gctagaatgt agtttcctgt tttttcacca tcgggaataa
    12901 aatctacagc aggactgaca aaagtccagt tgagattatt ttttgtacga agaagatcca
    12961 attcatccgc ttgagctttt gctagtggct taaattcttc aggaaaatca gacgtatcta
    13021 aaagtcgtgt cgtttttgtt tcatctatat aaaagcttcc tgatccccct acaactagaa
    13081 aacgtgtctg tgttccagca agaagctgat taaatagttc gattgatttg ctgtggagcg
    13141 gtagcgtatc tggtgtataa gcaccaaacg ctgaaataac agcatcaaat ccagtaagat
    13201 catcttttgt caactcaaat aaatcttttt taataataga ctcagattga cttttgtttt
    13261 cagaacgaac aatagccgtt acttcatgtc ctcgtttgac tacttcttca acaattgctt
    13321 tccccgcttg tccatttgct gcaataactg ctagtttcat tttttatacc tctcttattg
    13381 taattatttt agttacaaca attgtgacac tcttaataat caatgtcaat agtcttgctt
    13441 aattattatc aaaatatttc taccaagaaa actaactatg attctagtga aaagaaaaat
    13501 cttctttgtc aacaaattta ctttcttgtt ttaaacatgc tataataatc atagcaagag
    13561 atctaagttg tctgtttttt taaaacgagg tgattatcat gcgtagattc tattcccatc
    13621 tcccctacta tctggtcata ttattctttt attggccact ttatgagttg ttcttactag
    13681 ttgtttctga cccccttaca ctcaaggaac tctatataaa caatcttctc ttctttacac
    13741 ctctggtaat cttgattata tcgttactct atagctaccg tttccgtttc tcactttgat
    13801 ggttagttgg taacggactg ctcttttact ttactatcat aacctttggt gagtttatac
    13861 taatttactt gctaatctat gaaacagttg ctctggtcgg catggattct ggtattagca
    13921 tcaagcatat tctacaaaaa atgaaaaaca aaaaactttc acaaaatcct tgaaaaatct
    13981 cacaatcatg ctataataat ccatagagac aagtcactta gtccctttct actagagagt
    14041 gcgtggttgc tggaaacgca taggaagtct aaactgatac tactcttgag ttttttatga
    14101 aaacataaaa cggtggccac gttagagccg atcagaggtg tccctctctt ttgaggtaca
    14161 taaatgaagg tggaaccacg ttgcgacgtc ctttcgagga tgtcgcattt ttttattagg
    14221 atactaatta tggagttgca agaattagtg gagcgcagtt gggcaatccg acaagcttat
    14281 cacgaactgg aagttaagca tcatgatttc aagtggacgg tagaagaaga cctcttggct
    14341 ttatctaatg atattggaaa tttccaatga ctggtgatga caaagcaagg acgctactat
    14401 gatgaaacac cctacacact ggaacaaaaa ctttcagaaa atatctggtg gctattagaa
    14461 ctttctcaac gtttggatat agacattctg acggaaatgg aaaacttcct ctctgataaa
    14521 gaaaagcaat tgaacgttag gacttggaag tagtctgctg ataaaaaatc aatgcttaga
    14581 aactatgaaa taataaaaaa ggagaacatc atgattaaca ttactttccc agatggcgct
    14641 gttcgtgaat tcgaatctgg cgtaacaact tttgaaattg cccaatctat cagcaattcc
    14701 ctagctaaaa aagccttggc tggtaaattc aacggcaaac tcatcgacac tactcgcgct
    14761 atcactgaag atggaagcat cgaaattgtg acacctgatc acgaagatgc ccttccaatc
    14821 ttgcgtcact cagcagctca cttgttcgcc caagcagctc gtcgtctttt cccagacatt
    14881 cacttgggag ttggtccagc catcgaagat ggtttctact acgatactga caacacagct
    14941 ggtcaaatct ctaacgaaga ccttcctcgt atcgaagaag aaatgcaaaa aatcgtcaaa
    15001 gaaaacttcc catctattcg tgaagaagtg actaaagacg aggcacgtga aatcttcaaa
    15061 aatgaccctt acaagttgga attgattgaa gaacactcag aagacgaagg cggtttgact
    15121 atctatcgtc agggtgaata tgtagacctc tgccgtggac ctcacgttcc atcaacaggt
    15181 cgtatccaaa tcttccacct tctccatgta gctggtgcgt actggcgtgg aaacagcgac
    15241 aacgctatga tgcaacgtat ctacggtaca gcttggtttg acaagaaaga cttgaaaaac
    15301 taccttcaaa tgcgtgaaga agctaaggaa cgtgaccacc gtaaacttgg taaagagctt
    15361 gacctcttta tgatttcaca agaagtggga caaggtttgc cattctggtt gccaaatggt
    15421 gcgactatcc gtcgtgaatt ggaacgctac atcgtaaaca aagagttggc ttctggctac
    15481 caacacgtct acactccacc acttgcttct gttgagcttt acaagacttc tggtcactgg
    15541 gatcattacc aagaagacat gttcccaacc atggacatgg gtgacgggga agaatttgtc
    15601 cttcgtccaa tgaactgtcc gcaccacatc caagttttca aacaccatgt tcactcttac
    15661 cgtgaattgc caatccgtat cgctgaaatc ggtatgatgc accgttacga aaaatctggt
    15721 gccctcactg gccttcaacg tgtacgtgaa atgtcactca acgacggtca cctattcgtt
    15781 actccagaac aaatccaaga agaattccaa cgtgcccttc agttgattat cgatgtttat
    15841 gaagacttca acttgactga ctaccgcttc cgcctctctc ttcgtgaccc tcaagatact
    15901 cataagtact ttgataacga tgagatgtgg gaaaatgccc aaaccatgct tcgtgcagct
    15961 cttgatgaaa tgggcgtgga ctactttgaa gccgaaggtg aagcagcctt ctacggacca
    16021 aaattggata tccagattaa aactgccctt ggaaaagaag aaaccctttc tactatccaa
    16081 cttgatttct tgttgccaga acgcttcgac ctcaaataca tcggagctga tggcgaagat
    16141 caccgtccag tcatgatcca ccgtggggtt atctcaacta tggaacgctt cacagctatc
    16201 ttgattgaga actacaaggg ggccttccca acatggctgg caccacacca agtaaccctc
    16261 atcccagtat ctaacgaaaa acacgtggac tacgcttggg aagtggccaa gaaactccgt
    16321 gaccgcggtg tccgtgcaga cgtagatgag cgcaatgaaa aaatgcagtt caagatccgt
    16381 gcttcacaaa ccagcaagat tccttaccaa ttaattgttg gagacaaaga aatggaagac
    16441 gaaacagtca acgttcgtcg ctacggccaa aaagaaacac aaactgtctc agttgataat
    16501 tttgttcaag ctatcctagc tgatatcgcc aacaaatcac gcgttgagaa ataagagtct
    16561 agcataaaag cctccaatct ggaggctttt tctcatctat ttttactcaa ggactaagtt
    16621 cacttgagca aactgaatcc gcactgtcgt tccttttccg acctcagact cgatacgaat
    16681 ctggtgcccc agttcttcag aaattttctt agatagataa aggccaagtc cagaggactg
    16741 ctgggtcaaa cggccattgt atcctgaaaa gccacgttca aatactcgga ggacatcact
    16801 gttttttatc ccgattcccg tatctttgat acaaagctct tggtcatcca tataaatctc
    16861 cagaccacct tccttggtgt acttgagact gtttgagatg atttgctcaa taaccactag
    16921 cagccacttt ttatccgtca cgatttcttt atcaaggtca tgtagattga catttaagcc
    16981 tttttgaata aagaaaagag catatttacg aattatttcc ttgaccaagt cctcaatttg
    17041 aacctgcttt aagagcaaat catcatggaa actttctaaa cgcaggtact gtaaaactag
    17101 gttggtatag gagtcgattt tgaaaatttc ctgttctagc tgctgcttca gttggcggtc
    17161 gaccacttct gcaactaaga gttgactggc tgcaatgggg gtctttatct gatggaccca
    17221 caaggtatag taatccagca aatccgtcag ttttctttct gcttttgacc tctgctgata
    17281 gagttccatc tcacgcgctt ctaatttttc tgctaaagct atttccaaag gagacttggc
    17341 ttccctctct ccatagagaa gttcctggcg atagacctgc gtttccacca atatgtccca
    17401 agtgaaaaat aagatggtta caaagcaaca caagaagaaa aagtagagga agtaaattcc
    17461 tagactggca aataaaaact gaaagagtaa gacaagaaat gccaaagaaa gcagatagat
    17521 aaaaagacga ctacgggagc gcagataggc tagaaaaaat tgtttccaat caagcatgct
    17581 tcaatccgta ccctattcct ttcttggtct cgataaatcc taccaatccc tgctcctcca
    17641 actttttacg caaacgagcc acattgacag agagggtatt atcatcaatg aaaaagtcac
    17701 tgttccaaag ttcccgcatc aggtcgtcac gtgctacgat gttgcctgca tgctcaaata
    17761 acacgcgtaa aatctggaat tcattcttgg tcaaattcaa gacttgccct tgataatgta
    17821 aatccatgga tttggtattg aggataacac cagcatattc cagcaaactc tcatcacgcc
    17881 caaactcata ggaacgacgc aacaagccct gaaccttagc taaaagaacc tgctggtcaa
    17941 aaggcttggt cacaaagtca tccgccccca tattgattgc catgacaata tccatagcct
    18001 ggtctctcga agaaagaaac atgataggta ccttggaaat cttgcggatt tcctgacacc
    18061 agtgataacc attaaacaag ggcaaaccaa tatccatgag gaccagatga ggttccgact
    18121 gaacaaatag actcaaaact tccataaagt cttctaccag gaccacttca aatccccatt
    18181 cagagagcat tttcccaatc tgttgacgaa tgacctgatc atcttctatt aataaaatct
    18241 tgtgcatgcg cttctccttt tccattatta taacagattt ttccatgcta gatggtctga
    18301 aactgaattt gaaatagcct gtttttagcc agtacaaaca ggctatgcta ctagctaatt
    18361 tgagggaaat ttgctaagat aaataaaaag aaaggagctc ttatggccaa tatttttgac
    18421 tatctgaaag atgtcgcata tgattcttat tacgaccttc ccttgaatga gttagacatt
    18481 ctaaccttaa tagaaatcac ctacctctcc tttgataatc tggtctccac acttcctcaa
    18541 cgtcttttag atctagcacc tcaggttcca agagagccca ccatgcttac tagcaaaaat
    18601 cgccttcaat tattagatga attggctcaa cacaagcgct tcaaaaattg caaactctcc
    18661 cattttatca acgacatcga ccctgaactg caaaagcaat ttgcggctat gacttatcgt
    18721 gtcagcctcg atacctatct gattgtcttt cgtgggacag atgacagtat cattggctgg
    18781 aaggaagatt tccacctgac ctatatgaag gaaattcctg ctcaaaagca cgcccttcgc
    18841 tatttaaaga acttttttgc ccatcatcct aagcaaaagg ttattctggc tgggcattcc
    18901 aagggaggaa atctcgctat ctatgctgct agccaaattg agcaaagttt gcaaaatcag
    18961 atcacagcag tttatacatt tgatgcacct ggtctccatc aagaattgac acagactgcg
    19021 ggttatcaaa ggataatgga tagaagcaag atattcattc cacaaggttc cattatcggt
    19081 atgatgctgg aaattcctgc tcaccaaatc atcgttcaga gtactgccct gggtggcatc
    19141 gcccagcacg atacctttag ttggcagatt gaggataagc acttcgttca actggataag
    19201 accaacagtg atagccggca agtagacaca acctttaaag aatgggtgac cacagtccct
    19261 gacgaagaac ttcagctcta cttcgacctc ttctttggca ctattcttga tgctggtatt
    19321 agctctatca atgacttggc ttccttaaag gcgcttgaat acattcatca tctctttgtc
    19381 caagctcaat ccctcactcc agaagaaaaa gaaaccttgg gtcgccttac ccagttattg
    19441 attgatactc gttaccaggt atggaaaaat agataatact cttgaaaatt aaatgtatac
    19501 aaaacaaaag acctagaata catactttca tgtgcattct aagtcttttt aaatagaatc
    19561 taatagtcaa taaaaatcaa agagcattga gagataatgg ggcttggaac gtccctctcg
    19621 cttcaacaaa atgaccccat tatagattaa aaagatgcca cttagaaaaa gcaaaaaaag
    19681 gaagtaatac aaaggcaaat acataaaaag ctaactgaac attctcgtat ccatttttat
    19741 aaaaaaggta ggatagataa aaataacttg aaatgaggga taataaaaat aatactggat
    19801 tccacaaact tctattatac ttccaaaatg acactataaa ggctaataca attcctataa
    19861 cgagatacat ttcttactcc tttaatagct acattttatc ataattatcc aaagaaaaaa
    19921 agagggcatt tatccctctt aatccttcat ctgactctct gcatcggcca cgactttttc
    19981 tagactggtt tgaccaagtt ctgcctccat agtcaactga attctctcca atttttgatc
    20041 caaaacatca tgaatatgag ctcctacagg gcaatttgga ttcggattgt catggaaact
    20101 gaagagttga cctgtcttac caagacattc taccgcctga taaacatcta aaagactaat
    20161 atccttaagg tccttgacaa tctctgttcc gcccgttcca cgcgctactg aaatcagctc
    20221 tgccttcttc aactgggaca agatctttct gataatgaca ggattgaccc cgacactagc
    20281 agccagaaaa tcactggtca ccttgctttc cttcccttcg agggcaatga ttatcagcat
    20341 atgagtcgca atggtaaatc tacttggaat ttgcatcctc ttctcctttt tacgaggcta
    20401 ccctgcctct actcttcttt ttctattatt ataccctttt tagttgtaat gtcaatcgtt
    20461 accacttttc aaccagtcgt ctaactcccg atcgcagccc tctttctgag ccaattctct
    20521 caaaaattcc tgatgatgag tatggtggat cccattgacc agactttcat agtaaacctc
    20581 aaaataggga agtctcaggt ctttagccag ctgcaattca gctgccacat cgtagtctac
    20641 ccgtcggaag tccatatcta ccaggccttt gtcatcaaac tccaaaatca tatactgggc
    20701 ccgcaagtcc ttccgtagct gagcgtccaa aaagaaaggt tgcccaatcg aacccggatt
    20761 gacaatcaat tgcccaccag tcccgtaacg aagcaactgc tggtgaatat gtccataaac
    20821 agcaatatca cagggaggat gagtcaccaa gcggtcaaac tcctcttgtt tgccagtatg
    20881 aatcaactct cgcccccagt tcttatcagg cagatgatgg ctaattccca ccgtcaaatc
    20941 cccaaactga cgatgaattt gaagaggttg attgtggagc acttcaattt cttctaggga
    21001 aatttcctct aaaacatact ggcactggcg caagagatag cgttgactgg ggcgagtact
    21061 atccaattcc ttacggacac catgccaaag actgtcttcc cagtttccca aaactctagc
    21121 cgtaatcggt agttgatcca acaagtccaa aatccttcta cgccctgtcc ctggcatgag
    21181 aatatctccc aaaagccagt attcatccac tcctagctgc cgagcatctg ccaaaacagc
    21241 ctccaaggcg gtggtatttc catgaatatc tgaaagaaga gctattttcg tcatatccat
    21301 ctcctcgttt tttctcttgc aataagtata acataaaaag tcacagctag agaaatctag
    21361 ctttttttga tatactagat aaagatatta gacaagagga aacgaatgac cccaaacaaa
    21421 gaagactatc taaaatgtat ttatgaaatt ggcatagacc tgcataagat taccaacaag
    21481 gaaattgcgg ctcgcatgca agtctctccc cctgccgtaa ctgaaatgat caaacgaatg
    21541 aaaagtgaaa atctcatcct aaaggacaag gaatgtggct atctactgac tgacctcggt
    21601 ctcaaactgg tctctgagct ctatcgtaag caccgcttga ttgaagtttt tctagttcat
    21661 catttagact atacaagtga ccagattcac gaggaagctg aggtcttgga acacactgtc
    21721 tctgacctgt tcgtggaaag actagataaa ctgctaggtt tccctaaaac ctgcccccac
    21781 gggggaacta ttcctgccaa gggagaacta ctcgttgaaa tcaataacct cccactagct
    21841 gatatcaagg aagctggcgc ctaccgcctg actcgggtgc acgatagttt tgacattctc
    21901 cattatctgg acaagcactc acttcacatc ggtgaccagc tccaagtcaa gcagtttgat
    21961 ggcttcagca ataccttcac tatcctcagt aacgacgagg atttacaagt gaatatggac
    22021 attgcaaaac aactctatgt cgagaaaatc aactaatttc tcaagtcccc taccaaccct
    22081 gaaagtttta ttttggctct ttgtcaactg tagtgggttg aagtcagcta agctcgagaa
    22141 aggacaaatt ttgtcctttc ttttttgata ttcagagcga t
//
LOCUS       DAVMAH010000036        21493 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVMAH010000036 DAVMAH010000000
VERSION     DAVMAH010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21493
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.036"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(123..764)
                     /locus_tag="VYO94_001359"
     CDS             complement(123..764)
                     /locus_tag="VYO94_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1759991.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(761..2869)
                     /locus_tag="VYO94_001360"
     CDS             complement(761..2869)
                     /locus_tag="VYO94_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1759992.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(2921..3208)
                     /locus_tag="VYO94_001361"
     CDS             complement(2921..3208)
                     /locus_tag="VYO94_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1759993.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            3634..3954
                     /locus_tag="VYO94_001362"
     CDS             3634..3954
                     /locus_tag="VYO94_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1759994.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICRDDAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(4007..4594)
                     /locus_tag="VYO94_001363"
     CDS             complement(4007..4594)
                     /locus_tag="VYO94_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1759995.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            4836..5507
                     /gene="sdaAB"
                     /locus_tag="VYO94_001364"
     CDS             4836..5507
                     /gene="sdaAB"
                     /locus_tag="VYO94_001364"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV1759996.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKHGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            5516..6388
                     /gene="sdaAA"
                     /locus_tag="VYO94_001365"
     CDS             5516..6388
                     /gene="sdaAA"
                     /locus_tag="VYO94_001365"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV1759997.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            6410..7042
                     /locus_tag="VYO94_001366"
     CDS             6410..7042
                     /locus_tag="VYO94_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1759998.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(7302..9152)
                     /locus_tag="VYO94_001367"
     CDS             complement(7302..9152)
                     /locus_tag="VYO94_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1759999.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(9191..10351)
                     /locus_tag="VYO94_001368"
     CDS             complement(9191..10351)
                     /locus_tag="VYO94_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1760000.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENVEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNMLQ"
     gene            10409..11575
                     /locus_tag="VYO94_001369"
     CDS             10409..11575
                     /locus_tag="VYO94_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV1760001.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKEL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            11714..12040
                     /locus_tag="VYO94_001370"
     CDS             11714..12040
                     /locus_tag="VYO94_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1760002.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            12027..12620
                     /locus_tag="VYO94_001371"
     CDS             12027..12620
                     /locus_tag="VYO94_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV1760003.1"
                     /translation="MTRTEYLTQLELYLKKLPEAERIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            12613..13524
                     /locus_tag="VYO94_001372"
     CDS             12613..13524
                     /locus_tag="VYO94_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV1760004.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            13586..14650
                     /locus_tag="VYO94_001373"
     CDS             13586..14650
                     /locus_tag="VYO94_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760005.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKVEETIADFDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEESDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKFETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(14722..15582)
                     /locus_tag="VYO94_001374"
     CDS             complement(14722..15582)
                     /locus_tag="VYO94_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV1760006.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYYLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQLEIQPILG
                     QDFKTLAQEK"
     gene            complement(15857..16843)
                     /locus_tag="VYO94_001375"
     CDS             complement(15857..16843)
                     /locus_tag="VYO94_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV1760007.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(17115..18590)
                     /locus_tag="VYO94_001376"
     CDS             complement(17115..18590)
                     /locus_tag="VYO94_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV1760008.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(18694..19617)
                     /locus_tag="VYO94_001377"
     CDS             complement(18694..19617)
                     /locus_tag="VYO94_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1760009.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(19631..20560)
                     /locus_tag="VYO94_001378"
     CDS             complement(19631..20560)
                     /locus_tag="VYO94_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1760010.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(20879..21100)
                     /locus_tag="VYO94_001379"
     CDS             complement(20879..21100)
                     /locus_tag="VYO94_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760011.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQEELQKAVLF
                     LADEKGSEHTAAELIDNLKEVIAKLKANA"
     gene            complement(21054..21314)
                     /locus_tag="VYO94_001380"
     CDS             complement(21054..21314)
                     /locus_tag="VYO94_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760012.1"
                     /translation="MTGVSNPTTDSAPLVLAEAKKAFADDSLIEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT         6468 a         4651 c         3927 g         6447 t
ORIGIN      
        1 attttcaatt tgaaacaaaa aaaacctaga aatactacat aaaatgtcat tcctaggcgt
       61 atttatgcta tttttctctg gaaaacatga gtattcagcc agtcaaaagg agctgaatga
      121 actcattttc cctcgcccaa ttcaatgaca cgatgacatt gttgggctac ataagcatcg
      181 tgggtcacaa taatgactgt tttcccttct cgattcatct ctaagagaaa cttcaagacc
      241 aaatctctat tttcaggatc cagcgaacct gtaggttcat cggctaaaat cagctggctg
      301 ggttttaaga tggctctagc aactgcaatt cgttgttgtt cgcccccaga caactcggag
      361 accctttgat gcaaagtagc tgacaaacct actctctcta aaatctcttc cacctttttg
      421 agcttgtctt tcttaggcaa tttcacatat ttcagcgcca gcatgagatt gtactcgacc
      481 gtttcatcat caatcagggc aaaattttga aacagataag agatatgttc acggattatt
      541 gtttgcgact tagcagaatt aaccgctaga tttgtctgac caaaaatctc ataccgtccg
      601 ctataatcac catctatcaa acccaataaa tttaacaagg tcgacttccc actaccactc
      661 ttaccaacaa tagctaccaa atccccctga tcaatcctga gagataagtt atccaaaatc
      721 acttttcccc caatggtttt ggtaatattt ttcaactcaa tcataagatg ccccctttca
      781 ataactctac tagacttctt ttctccatcc tagaagctaa gcctagcaca aatagtatat
      841 ccagacatgt aaaacctgca aacagtagaa gtggtaagaa cgcatgggca aagaaaatca
      901 agactagaag agggaaacta tagcccagca agagcagaac gaggagagga cggtagcgat
      961 cgaccagttt ccaccccata aacttcttgg taatgatatc cctgcgcttc aataagaaag
     1021 ttgttactag taagaagtag gaaatcatca tgctaaggag accaaacaaa gcaaagagta
     1081 ggttaaaatt ccgaacagca tctcgataag aatccacttt ctcttgttga atggcttgaa
     1141 tagatgaaaa ttttaaataa tttccatctg acaatttctc aactaactct gtaatctctt
     1201 tttgatgttg aaccgtattt tcaattttaa tcggattatt taagccagtt gttgacaggg
     1261 aggctttctc atcccacatc atatcagaat cattgaccaa gctaataatt ggattggaga
     1321 gattttcctt tcgcttatca ctatatggga aaaatgacca atctccttca taataggcaa
     1381 tctcgacatc catctcctct atcgttcgtt tttgctgctc ttcatacttc atcgaatgaa
     1441 aggcaattaa cttccccaag agctgatttt tatcttcttc acctttcgta cttgctggca
     1501 tcaaaataac ttttttaata ccggtatctg gtagcttgaa tcccttgctc tttagaaaat
     1561 tgcgattcgc atagtaaaca tccaccgtat ctgttaactg atattgctga atctgttctg
     1621 attggacaaa attttttaca ggaagactgc tactctgcac atagcccgcc tgcgtttttt
     1681 ctaccaaatc ctgataaaat cgatagaaat aatctgtaga tttccctgac cctgctagct
     1741 cttcttgcca cagattatca ttgagtttga aggtttctaa ggtcaggtaa ttaccttgac
     1801 ttacccactg ttgctgataa gcaagttctt tgttttcttg ttctaaactt ctgcccaccc
     1861 caatcagtaa ggccgtcagt aaaatagttg tccctatttt catcacataa ttgaagataa
     1921 gaccaaattt gaaagatgaa aaacctttca gcagagagct gattgtcatt ttttggatta
     1981 agaggtaagt caaccaactg ataaagagat aaagctgcaa cagcaaaaaa tgagacaacc
     2041 acagcatagg aaacaaatct tttggcttat aatcaagcaa gaaaaacacg cctagattga
     2101 tcacaagagc cccacctagg aggaggtaaa ggttgccttt tacaacatca gctaaaacag
     2161 ccctatcttg aaaaccaagt aatttttgta ccccaactct tttcatctcc atcatcggtt
     2221 gatacactgt cactaacaca agaagcaaaa tagccaagac aaaaacaatg gcagataaaa
     2281 gcaaatctcg atttatgact tccactgcac ttttgtaggt cggctctagc aaggtagcct
     2341 ggtctatctt gaaaaaatcg ctccatttct gtacaatcct atccttgtcc atctcttgtg
     2401 tagaagttat cgtatagcga ccatttaaac tacgagatgt atccttgata taggtttgaa
     2461 aagtcataag ctgaataggt ttggctttta gaaaggtcgg aatcgtacca agtttattgg
     2521 aaatttcttt attactatag actccttcac catctgtggt aaaatcaaga gaagaaatcc
     2581 caaactcttg gtaggggaag gtatctttat caaaaacacc agacttgacc acctcatcac
     2641 cactgtctgt tttgatgatg gagactttat actcctttga tacatcctca aaaaatcgaa
     2701 gaacagacgc tgcaggttcg ttaatatctt tcaaatacaa atccaaagaa tctacagtct
     2761 ttcccatttc ttgaatccga accacttctc gtgtatagtt tacattaaaa acaaaaaaag
     2821 tggtacacag aagcaggagt aacatacaga aattactgat ttttttcata aaagtgcctc
     2881 cactacagtt ttccctctcc aaataggaga gggaagaatt ttactcaaat ccatagaaat
     2941 attccattcc tgttggcgga atcttggtga gggaagctct agcccatgcc tcaggttttg
     3001 cataatcctt agaggttcta cccccatgtc taacagttgc tgtatgatat cgagtagaat
     3061 gtaagtaatc agaatatcca aaagttcctg tccaacctac tccatagttc cattgaccac
     3121 cctcaaccca tactgctaaa gcatttgtag tagcaagtat accacatacc attaaagatg
     3181 caacaccaat tttaactaat tttctcatga tttatttctc ctattatcga gagctgttcc
     3241 gtaaaaacag ctatagtaat ttatcaacaa gtatcgtagt ccattggact caccttcctt
     3301 ctatctcatt tcatttttaa acaacgaact tactcttaac tagaagaata gttctcttct
     3361 gtatcaggtc tttgaacaac cagagtagta ttaatcacac tctaactatt actcaagaat
     3421 cagcccaata aacaacatgg atagcgcttt caaattttta aactcttatc ccatcctttt
     3481 atctatataa taagtgaaaa tataataact gtcaagtaat cgaagtgaat tttataaaaa
     3541 aaattacaag ccaaatttgt aaagtttaca ctaagccgct agggcaatcg tctatcagaa
     3601 tgtccgttta tctgtcaata atccgagaaa atcttgcaac gcttagaagt ctataaaaac
     3661 tatcaacatt tatatgactt gcgaatagca atcctgctca acctttccac actctatcta
     3721 tacaatcaag ataaaaacat gtgtaagcaa atctgctaca ctttactgga ggacgccaag
     3781 aataagaaaa gctacgatag gctggctatc tgctatgtcc ctattgggat ttgtagggat
     3841 gatgcgaaac ttatccaaaa aggtttctca ctcctagagc taaccgagga aacttctatg
     3901 ctgtctcatc tcaaaaaaga agtagagacc cattatcaac caaagaaatt ataaaaaaag
     3961 tcgagggatt tcctcgactc tttacatatt atttgttcgt tagttcttaa taccagccat
     4021 tgttaagcca gaagttttta gcagctgtcc atgaaccgta acgtcctgca acgtaggcat
     4081 ctgctacacg ttcttggttt tcagctgagt agtcaccgtt caggtatgaa tctgttaatt
     4141 ggtaacgtcc gatataacgt ccatttgtag ctgtatagct accacctgat tctttttgag
     4201 cgatccattc tttggcttct gcttcagatc cgcttacagt tgaaacaact gtttcactta
     4261 ctactggagt ttctgccact ggagctgaaa cagtttcatc ttgagcggct ggtgccgcat
     4321 aagtagctgg cgctggtgtt gcaacaggcg ctacagggcc atcgataacc aactcttgac
     4381 caacataaat caaatgaatg ttatcaatgt ggttgttttc tgccaatttt tcaactgttg
     4441 tgttgtgagt ttcagcgatt tctgaaagtg tatcaccttc tttaacagtg taagttgatg
     4501 attcttgagc agatacaaat gatggagcaa atactgcaaa caaggcagct actcctgcaa
     4561 gagttgcttt aatcttttta gttattgatt tcatattcga aaattctcct tctttctata
     4621 gttctatcat accctttaaa tattaccgtt tcttgacact tttatgtaga aatattacaa
     4681 aattattttt tatttcccta aataaggtgt tttttgtcat aaaagatact atttttatgc
     4741 tatttgaggt attagaaagg ttttcatcca caattaaagc caagcccctc attctttgat
     4801 ataatagaga taagaatttt tataagggga aactgatgaa atcacttcgt tttcaatctg
     4861 tctttgatat catcggacca gttatgattg gcccatctag tagccatacc gctggtgctg
     4921 ttcgtattgg gaagattgtc tcttccattt ttgatgatac tccgacagaa gttgaattcc
     4981 aactttttaa ctcatttgcc aagacctatc gtggtcacgg aacagaccta gcccttgttg
     5041 caggtatttt aggaatggat acagatgatc ctgaaattcc aaatagtctg gaaattgccc
     5101 acaagcatgg tatcaagatt gtctggacca ttcagaaaga cagcaatgcc cctcacccta
     5161 acaccactaa aattactgtt aaaaatgccc acaagaccat cagcgtgact ggtatttcta
     5221 tcggtggagg aaatattcag gtaaccgaac tcaatggttt tgccgtctct ctcaatatga
     5281 atacaccgac tatcatcatc gttcatcaag atattccagg tatgattgcc cttgttacag
     5341 aggcgctttc ccgctatggt atcaatatcg cccagatgaa tgtcactcgt gaaaaagctg
     5401 gtgaaaaagc cattatgatt atcgaagttg acagtcgcaa ctgtgatgag gctatcgaag
     5461 aaattcgaaa aatccctcat ctccacaatg tcaatttctt taaataggag gaagcatgtt
     5521 ttattctatc aaagaattgg tcgagcaagc agatctggac tttcaaggaa atgtcgcaga
     5581 actcatgatt acaacagagt ttgaattgac cggtcgcgaa cgtgaagaag tcttccttct
     5641 catggaacgc aatctggaag ttatgaaagc ctctgtccaa cttggcctca atgaaaataa
     5701 atctcgtagt ggcctgacag gtggagatgc tgccaaattg gatcactaca tcgaaaacgg
     5761 aaaaactctg tcagattata cgattctctc ggctgcccga aatgccatcg cagtcaatga
     5821 acacaatgcc aaaatgggct tggtctgtgc cactccaacc gctggaagtg ctggctgtct
     5881 gccatccgtt ctcactgctg ctattgaaaa attagacctc agccacgagc aacaattgga
     5941 tttcctcttt gctgctggtg cctttggact agtcatcgca aacaatgcct ccatctcagg
     6001 tgctgagggt gggtgtcaag ctgaagttgg ttcagcctct gctatgagtg ctgccgcctt
     6061 gactctggct gcaggtggaa caccttatca ggccagtcaa gctattgcct ttgtcattaa
     6121 aaatatgcta ggcctcatct gtgaccctgt tgcaggtttg gtcgaagttc cctgtgtcaa
     6181 acgtaatgcc atgggagcta gctttgcttt catcgcagca gacatggcct tggcaggtat
     6241 cgaatctaaa atccctgtgg atgaagtgat cgatgccatg taccaagtag gagcaagcat
     6301 gccaactgcc tttcgtgaaa cagctgaagg tggactcgct accaccccta ctggtcgtcg
     6361 cctccaaaaa gaaattttcg gagaataagc ttatcaaata ggagaaacca tgacctctat
     6421 cacagcgatt tttttcgatt tggatggaac cctcgttgat agttctatcg ggattcacaa
     6481 tgcctttacc tataccttta aagagctggg ggtgcctagc cctgatgcca aaactattcg
     6541 tggttttatg ggaccacctc tcgaaagtag ttttgcgacc tgcctgtcca aagaccaaat
     6601 ttctgaagcc gtgcagatat atcgttctta ctataaggca aaaggcatct atgaagctca
     6661 actctttcct cagattatag acttgcttga ggagttatcg agcagttatc cactctacat
     6721 caccacgaca aaggatacat ctactgctca agacatggca aaaaacttgg aaatccatca
     6781 tttctttgat ggcatttatg gttctagccc tgaagcaccc cataaggcag atgtcattca
     6841 ccaagccttg cagacacatc aactagcacc agaacaagcc atcatcatcg gagataccaa
     6901 gtttgatatg ctgggagctc gagaaacagg tattcagaaa ttggccgtca cttggggatt
     6961 tggagagcaa gcagatctac taaactatca acctgattat atcgctcaca aacccttaga
     7021 agttttggcg tattttcaat agcatagact gggtaacaat tccatttcag aagaaaatga
     7081 agtaatactc aatgaaaatc aaagagcaaa ctaggaaact agctgcgggc tgctcaaaac
     7141 actgttttga ggttgcagat agaactgacg aagtcagtaa ccatatctac ggcaaggcga
     7201 cgttgacgtg atttgaagag attttcgaag agtataagtc tctacataat aaaacgcata
     7261 ttaccaaggt tgtttaactt gataatatgc gtttttcttt tttattcaat gtgggttgtt
     7321 tgattagcaa aggcgataat agcttgcttc aactcatctc cactgagagt gcggaactct
     7381 ccaatctttt gattgatgga ttctaaaggc atgacattaa ccttaccaac gaaaatctta
     7441 tccataactt gattgtcaac gagttcggtt gataccaaga gttcttcgta gagtttttca
     7501 cctgggcgga ttccaacttc aacgattgga atttcacttt cagtgtggcc acttagaagc
     7561 accatcttct tggccaagtc ataaatcttg actggtttac ccatatcaag gataaagact
     7621 tccccatctt tggcataagc accagcatgg ataaccagac ggctagcttc tggaatggtc
     7681 ataaagtaac gggtcatgcg gaagtctgtc accgttacag gcccaccttc agcaatttga
     7741 cgttcaaaga ctggaatgac actaccacgg ctaccaagaa cattcccaaa acgaactgca
     7801 cagtaggttg attggctacg ttggttaaag ccagtgacaa tcaactccgc cacgcgcttg
     7861 gttgctccca taacatttgg tggattgact gccttatctg tcgaaatcat aaccatctta
     7921 ggcaccttgg cttcatcaac ggctctagca acattgtaag ttccacggat attgtttttg
     7981 aaggcttctt ttggattgcg ctccatcata ggaacatgct tgtgggctgc cgcatgataa
     8041 acaatagcag gtttgtactg ctcaaagact tgcaacaaac gatcatagtc ttgaatgtcc
     8101 gcaatcacag gtacataatc aatcccttgg aacttacgaa tcaattcatg ataaacaagg
     8161 tagattgagt tttccccatg accgagcaag acaatgcgtt caggattgaa gcgactaact
     8221 tgacgacaga tttcagaacc gattgaacct ccagctcctg tgactaagat ggtcttacct
     8281 gtcagttctg cacccagacg cgattcgtca agacggattt cctgacgacc caaaaggtcc
     8341 gtaatatcaa ttttttggaa gccagtacct gcttggtgaa ggccctgaac aacagtttca
     8401 accttaggca tcttgtaaca tttgacaccc agcttattac acatctgcaa gatacgctca
     8461 tattctgacg gatccagcga cggaatcgca acgatgacac gctcgatttg atggcgtttg
     8521 gctaattcag gcagattgtc ataagagccc aaaacaggaa taccaccaag tttttgaccc
     8581 tttttcttag aatccttatc caaaataccg accagttcta attcactggt tggatgttgg
     8641 taactatcca taaaaagagc cccaccatca ccggcaccaa tcaagaaggt ccgacggtgt
     8701 tctccatcac cactaccttt tttgcgtctg gagtagatta actgccaagt aatccgtggc
     8761 aataaaatca agaaggtact caacaagata aagagaatga tgaaacggat ggagaagagt
     8821 ggcaagaagg cataacagat actatatgac aagacactgc tagcagtcac accaaaaaag
     8881 attttcatga aatccgtaat cttgctgtaa cgactaatgc tcgcgttcaa cccccaaaaa
     8941 ccaatcatca attgatagaa caagaaggcc aaactcgtat agataatgta gtcaacaggt
     9001 gctggattaa tcagcccata aaataaaata taagatacaa tgatggaaac caccatactg
     9061 aaaatatcaa atattcccca gaaaacctgc ttttgttgtt tatttaaaat ttccaccaga
     9121 tcaatcacat aatctgttag ttttttattc atagaaatct actcctcctt aaaagagttt
     9181 tactatattg ttattgtagc atattttgat ttatttggct tattttatcc aaataaatta
     9241 ttgttccctt gtactccttc ttccatttaa atcctctaat taaacctaca atcgtcccaa
     9301 agccataagc aaagtgaatg gaaaataaaa gaaagggcat cacaattaga aatccatttt
     9361 tatgttttaa taaagtcagc aaagtgagta gtgacaaaag tagaaaatag gcacctaata
     9421 gtaaagttat gaatacgaat gtgatcggta acaatgctag actaaacaca agactcaaaa
     9481 caaataaaca aggaacatag tgaaataatg ataaacactt aaactgaaca tgacttgtca
     9541 agccaatcca caaaccattt gaatactttt gatgcagcat tttcttgaat gttggtcgaa
     9601 tatactgata agatagaata cttgggctat agcggatttt ataaccatgt tctcgaattc
     9661 tataatgaat atcattatct tcagttcggc caagttgctc atttactaaa ccaaccttct
     9721 ggaaaacctc tcgtttatac atcccatgaa aaatagaaga aacatatcta tcctcggaac
     9781 tatttcgata attggcaatg ctactgccaa acatattttc ctcaacaaga tgcaaggtct
     9841 ctgcccattt tccttttcct tcgacaatcg tcggtctagg ccccccacag acaaattcac
     9901 cttgttgaat aatagccaca ttgttcatta caaaactctc agtaactttt gaatgagcat
     9961 caatttttaa aataaggtcc cctacagaat gtttaactcc caggttaaaa ccactagctt
    10021 gatttttctt aggattgtta tacaatctaa ttgagttaaa ctctgtatct tcctttataa
    10081 attgctgaat gatagctgtg gtcccatctg tggacatagc atttataaat agaatttcaa
    10141 cattctcttt aggataggtt tgatttttta agtcttcaat tagaccaggc agatattttt
    10201 cttcattgta tgcactgatt acaatggata cgagaagact ttcaacattt tgagtcacta
    10261 ctactctcct gaatttttcc ttccaccatt ctatcataat tttcaagact ttcccatttt
    10321 tatcttgaaa gccagaaacc ttacttgaca ttatagtgaa aaagccttaa aataagctgt
    10381 tattaaaatc agctagaaga ggtattatat gaaaaagcaa tcactctttt ttgttccagg
    10441 tattatcctg attggtgttt ccttgcgaac tccttttact gttttaccca ttattttggg
    10501 aaatatttcg caaggtctgg aggtagaagt tagttcgctt ggtgtcttga ccagcctgcc
    10561 tctccttatg tttaccctct tttcaccatt ttctacccga ctggctcaga aaatcggctt
    10621 ggagcatctc ttcacctaca gcctcttctt cttgaccatc ggctcactca ttcgactaat
    10681 caatctgccc ctgctctatc taggaacctt gatggttggg gcaagtgtcg cagtcatcaa
    10741 tgtcctgctt cctagtctta tccaagccaa tcaaccaaag aaaattggtt ttctgaccac
    10801 cttatatgta acgtctatgg ggattgcaac ggctctggct tcctatctag ctgtgcccat
    10861 tacacaagcc agttcttgga aagaacttat cctcctcctc acgttactct gtctagcaac
    10921 ttttttggtc tggctcccaa atcaccgcta taatcataga ctagctccac aaaccaaaca
    10981 aaaaagtcaa ataaaggtca tgcgtaataa acaggtttgg gcaattatta tcttttcagg
    11041 ttttcaatcc ttgatctttt acaccgtcat gacctggtta cctaccatgt ctatccatgc
    11101 aggtctatcc agtcacgaag ctggcttgct gacttctatc ttatctctga ttagcattcc
    11161 tttttcaatg accatcccaa gcctgacaac cagtttatct actcgcaacc gtcagctcat
    11221 gctcactctg gtttcactag ctggtgtggt cggcatttcc atgctctttt tcccaatcaa
    11281 taatttcatt tactggctta ccatccatct cctcatcgga accgcaacca gcgccctctt
    11341 cccttatctc atggtcaact tttcactcaa gacaagcgcc cctgaaaaga cagcccaatt
    11401 gtccggccta tctcaaacag gaggctatat cctagcagcc tttgggccaa ccctctttgg
    11461 ttacagtttt gacctgttcc actcttgggt accagctgta gctgccctct tgctcatcta
    11521 tatcctgatg actgtggccc tctttacagt ggacagagcg gataagatcc tttaaacttc
    11581 tagttttagc tagaagtttt ttatatataa aaattttaca catttctctt gacagggctt
    11641 tcttttagat gtacaatgta tgtgtagaaa aattatatat aaaaatctta cacattagaa
    11701 aaggaggttt cccatgtact ttccaacatc ctctgccttg attgaatttc tcatcttggc
    11761 tgtactggag cagggtgatt cttatggtta tgagattagc caaaccatta agctgatcgc
    11821 taatatcaaa gaatccacac tctatcccat tctcaaaaaa ttggaaggca atagctttct
    11881 gacaacctat tctagagagt tccaaggtcg catgcgcaaa tactactcct tgacaaacgg
    11941 tggtatagag cagctcttga ccctaaaaga tgaatggaca ctctatacag acaccatcaa
    12001 tggcatcata gaagggagta tccgccatga caagaactga atacctgact cagctagaac
    12061 tctatctcaa gaaactacct gaagctgagc gtatcgaagc catggactat ttcagagagc
    12121 tctttgacga tgctggagtc gaaggagaag aagaactcat cgctagtttg ggaactccca
    12181 aagaagcggc ccacgaagtt ctatccaatc ttctcgataa aaaaatcaat gaagcacccg
    12241 ctcaaaaaaa taaccgacaa attttacata tcgccttgtt agccctcctt gcagcaccta
    12301 tcggcattcc tctgggaatc gccatcctcg tgaccctgtt cgcaatcctt gtagccgctt
    12361 tgactgtcat tctggctttc tttgcagttt ccatactggg tatcatcggc ggattcctat
    12421 ttttagttga aagtttcact atcctcgccc aagccaaatc agcctttatc ttgatttttg
    12481 gttctggttt actggctatc ggtgcttctt cgctagtttt acttggcatt tcctatgtag
    12541 ctcgcttctt cggtctactc attgttcgtc tggtacaatt tgttcttaaa aaaggaaaga
    12601 gaggtaatca gcatgcgtaa atggacaaaa ggatttctca tctttggtgt ggtgactacc
    12661 gttatcggct ttatcctgct ttttgtaggt atccaatctg acgggattaa gagcctactt
    12721 tccatgtcca aagaacctgt ctatgatagc cgtacggaaa agctaacctt tggcaaggaa
    12781 gtcgaaaacc tagaaattac tctccaccaa cacgcgctca ccatcacaga ctctttcgat
    12841 gatcaaatcc acatttctta ccatccatct ctttctgctc accatgatct tatcaccaat
    12901 cagaacgata gaactctgag tctcactgat aagaaactgt ctgaaactcc gtttctctct
    12961 tctggaattg gtgggattct tcatatcgca agtagctact ctagtcgttt tgaagaagtt
    13021 attctccagc taccaaaagg gagaactcta aaagggatca acatctcagc caatcgcgga
    13081 caaaccacca tcataaatgc tagccttgaa aatgcaaccc tcaatacaaa cagctatatc
    13141 ctccgaattg aaggaagtcg tatcaaaaac agtaaactca caacgcccaa tatcgttaat
    13201 atctttgata cagttcttac agatagtcag ctagagtcaa cagagaatca cttccacgct
    13261 gaaaatatcc aagtccatgg caaggttgaa ctgactgcca aagattatct cagaatcatc
    13321 ctagaccaga aagaaagcca acgaattaac tgggacatct caagcaacta tggttctatc
    13381 ttccaattca caagagaaaa gcctgaatca agaggtacgg aattaagcaa cccttacaaa
    13441 actgaaaaaa ccgatgtcaa ggatcaactc attgcgagat ctgatgataa tattgatcta
    13501 atatccacac caagcagacg ttgacaaaaa cgcttacatc tgctactatg gaagcatatt
    13561 tatctaacca aaaggaggtt ctaccatgaa acaagaatgg tttgaaagta atgattttgt
    13621 aaaaacaaca agcaagaaca agcctgaaga gcaagctcaa gaggttgcag acaaggttga
    13681 agaaacgata gccgatttcg atacaccaat tggaaaaaat actcaagtag aggaggaagt
    13741 ctctcaagct gaagtcgaac tggaaagcca gcaagaagag aaaattgaaa ctcctgaagt
    13801 cggtgaagcg agaacagaaa tagaagaaaa gaaggcatct aattctactg aagaagagtc
    13861 agacctttct aaagaaacag aaaaagtcac tatagctgaa gagagccaag aagctcttcc
    13921 tcagcaaaaa gcaaccacga aagagccact tcttatcagt aaatctttag aaagtcctta
    13981 tatccccgac caagctccaa aatctaggga taaatggaaa gagcaagtgc ttgatttttg
    14041 gtcttggcta gtggaagcga tcaaatctcc tacaagtaag tttgaaacaa gtatcacaca
    14101 cagttacaca gcctttctct tgctcattct gttttctgca tcttcctttt tctttagtat
    14161 ctatcacatc aaacatgctt actatggaca tatagcaagc attaacagtc gcttccctga
    14221 gcagctagct cctttaactc ttttttctat catctctatc ctagtagcga caacactctt
    14281 cttcttttca ttcctcttgg gtagtttcgt tgtgagacga tttatccacc aggaaaagga
    14341 ctggacgcta gacaaggttc tccaacaata tagtcaactc ttggcaattc caatcttcct
    14401 cactgctatt gctagtttct ttgctttctt tgatagccta cgatttacag ccctcttgtg
    14461 tgtgattagc attggaatca ttctgcttgc cagtctccat atcattacaa gaccaagtca
    14521 agcaagtgaa accgactcct tctatcaatt attcttgtct gtccttgtga acggagttat
    14581 tatcctcctc ttctttgtag ctgaagtggc actgattgga gattatcttc gtatcttggc
    14641 ctttctttaa aattcaatcc tgtcatcctt ggcaggattt tttctatgtc aaaaaagcaa
    14701 gtcgattgac ctgcttctgc tttacttttc ttgtgctaat gttttaaaat cttgtcctag
    14761 gatgggttgt atttctaatt gattggcgtc tagctggtgg taaaaagatg ggggtaacac
    14821 ctctaagaat tttgcatagt ccaagcgagc tatggattca tagtcttctg gtttagagcc
    14881 gtctcctgtg atttgaacca agtcaatctc ccactggact tccttatcca ccaattgctc
    14941 aatataggct gcaggaacaa acggttctct cggtaaaact gtcttgactc cttgagctag
    15001 atagtaaacg ccatgcactt ttccttctcc atcctgatag aaggaaactc tcgcaaagta
    15061 ggcatctgtc tcttgaaccg cacgcacacg cgcttcaaac tgagccaagc catctgcctc
    15121 taaaaagctt ttcaagttct cacgactaaa gaaaatagga ttaaaaattc cttggcaaat
    15181 cgtaaaacga gctacagggt ctgctagata ggcttgaata cttgcttgga aataagcttc
    15241 aaaatcaaaa ccatctagcc cttcaatatc agtccctgta taagcaagca aagcatctaa
    15301 aaatgacttg ataatctgcc agtctgtctt tgttagtagg tcaggaagat cgacacggta
    15361 agccttttga ccatcagcat aactgacctt aaaaagaaat tgtgattgcc ccactatcgc
    15421 acactcaata tactcgagac gattaagagg ctgacggaga tagactacat catagctatg
    15481 tgactccaaa ccgtctagca aggccaagat cgacttggca ttcaaaatct cttgttctcc
    15541 taaaatgctc tgtttatttg gaataaaaaa tgttttcgcc ataactggac tcctttgaaa
    15601 tcgtttacat acagtatacc ttatttttct gaaagataca aaaacaaact ttatattctt
    15661 cgaaaatctc ttcaaaccgc gtcagcttcg ccttgccgta gatatatgta actgacttcg
    15721 tcagtcttat ctacaacctc aaagcagtgc tttgagcagc ctgcggctag cttcctagtt
    15781 tgctctttga ttttcattga gtattagatt tttgagtaca aagcatagaa aaacagcccc
    15841 tgaggactgt ttgatcttat acagtagctg cctgatccaa gctttcaccg atagcggcta
    15901 ggcgctcaat cacttcagct tgtgtcaatt cattttttga aacatagcgg ttacgtgggt
    15961 gaacacggca ctcgtgtgag catccacgaa ggtacttgtc ttcattttct tctgatgtca
    16021 agatacgacg gttacagaag ggatttccac agttgacata acgttcacat ggtgttccat
    16081 caaaccagtc tttccctacg atggttgggt tgacatggtt gacatcaacg gcgatacgct
    16141 cgtcaaatac gtacattttt ccatcccaaa gctcaccttg aacttctggg tctttaccgt
    16201 aagttgcgat tcctccgtgc aattggccga catctttgta gccttcacgg accatccagc
    16261 ctgagaattt ctcacagcga acgccacctg tacagtaaac cacgacacgc ttgtccatga
    16321 atttttcctt gttatcacgg acccattgtg gtaactcacg gaagttgcga atatctgggc
    16381 gaatagctcc acggaaatgt cctaggtcgt actcataatc gttacgtgtg tcaaggacaa
    16441 cggtatcttt atcaagaagc gcttctttga actcttttgg agacaagtaa gcacctgttg
    16501 tttcaagtgg gttgatgtca ttgtcaaagt cgttgtcttc caaaccaagg tggacaattt
    16561 ctttcttgta gcgaacaaac atcttcttga aggcttgttc actttcttcg tcaatcttga
    16621 accagagatc ttccatacct gggaggctgt gaacgtagtc catgtatttt tgagttgttt
    16681 catagtcacc tgaaactgtt ccgttaattc cctcgtcagc gactaggata cggcctttaa
    16741 gaccgattga tttacagaaa gccaagtggt ctgcagcaaa ttgctctgca ttttcaattg
    16801 gagtataaag gtagtaaagt aagacacgaa tatcttttgc cataagattt gttctctttt
    16861 ctattcttaa attttctaaa ttttttattt atccatacta gtatacctgc ttgagaaaac
    16921 gaatgcaatt tatttgactg gaaattgtag agggttctcg aaatttcctg aatggttaaa
    16981 ataaggacaa gagaaaacag ggatatctat atccttgtgc caaaaaaacc actgccttcc
    17041 ccagataaac ctgaggaaag cagtgattct tattttagga gttaggaatg aatacacgaa
    17101 atcaatttag ctgattattt tttgtttttc aagaattcat cgtattgttt ttgcatttcg
    17161 ttcaatactt tttcgtaggc accttcagat ttcaattttt ccatcaattc tggaatagct
    17221 ttatctgggt ctacagtacc agtgttgata gctgtatcaa attgttgcat tgtgttagca
    17281 atagctgaga tttcagattt cacattgtca gtattgaaga taaatccaag cgctggagat
    17341 tctttagctt ctgccaattc tttcttagaa ttttcgattt gttggtctgt aacgttttcg
    17401 ttgatgtaaa ggatccagtt gttaccagtg ttccatccac ccatgtgagt gtttcctttg
    17461 tagccatcaa gaacgcgaac acggttttct ttaccttcaa ttttttccca gttcttgcct
    17521 tctggaccgt aaacaagacc gttcaaaagt tctgggttcg tattcaagag gttcaagatt
    17581 tccattgatt tttctttgtt cttagagttg tttgagatga caaagttagc aacttgtgtt
    17641 gtttggtttt tcttgatgaa gttagtaatt ggtttgattt ggatatcttt gttggcaaca
    17701 cgtgaaagca agctgttacc gtagtcagct ggtcctactg tttcttcacg aacgaaccaa
    17761 gtatcttgtt gaaggtcaaa ggaagtatcg cttgttgcga cgtcttttgg aatgtagcca
    17821 gcttcataga atttgtgaag agtcttcaag tgttctttga aacgaggcac ttcgtaacgg
    17881 tttacaactt tagtagtatc gccttcaagg tcaataacga atggaagccc gtttgctact
    17941 gggtagtcaa aattatcaga tgggatgaaa actttaccaa tagcaaatgg tactacgtct
    18001 ggagcttttt ctttgatttg tttcaagact ggctcaagag tttcgtaaga agtaacacct
    18061 gaaatatcga taccatattt ggcaaggaga gttccgttga aggcaaagtt ttgagatgat
    18121 gcaacgttgg ctgcaactgg tacagcataa atcttaccat ttacagtatt acccttgata
    18181 taagctgggt caagtgcctt gtaaaggtct ttaccttctt ttttgtacaa ttctgtcaag
    18241 tcagcataag cacctttttg agcatttaca atatagttat ctgcaaaggc gatatcatag
    18301 ttttcaccag atgatgtgat aactgacatt ttcttaccat agtcacccca gccaaggtat
    18361 tggatatcca atttagcacc aactttttct tcgatgattt tgttggcatt tgctaacaat
    18421 tcatccaagt tatctggttt gtcaccgatt tggtacattt tgataacagg tttgtcacct
    18481 gaatcagcag cttttttact gttacctgtc aaatttccac aagcagcaag acctgcagcc
    18541 aaagcgacta cactagcaga tgcaaaagca tattttttcc agtttttcat gataaaaact
    18601 ccttttttta tttttaaact tataaacaat gtaatgatct taacttcacg caagggaagt
    18661 ttggaaatga gaaatgttct ttttcaataa gcactattct ttcacaccac cgatagtcaa
    18721 accttttaca aagtagcgtt ggaagaatgg atataaaatc gcgattggaa gggttgcaac
    18781 cacaaccatg gccatacgac ctgtttcttt cggtagagca actcccagtt gaccagtcaa
    18841 gccgaccgct ttggcaatgt agtccatatt ttgttggatt tgcatgagca aatattgcaa
    18901 tggatacaag ttatcactct tgatgtaaag aagggcgttg aaccagtcat tccagaaacc
    18961 aagagctgtc aaaagcgtga tggttgcgat acctggtagt gacaatggca aacagatttg
    19021 gaagaaaatc cgggcctcac tggcaccatc gatacgagcc gattcgagaa tggcttctgg
    19081 aatggtcttc ttgaagaagg aacgcatcaa gatgatgtta aagggggaga gaagcattgg
    19141 cacaatcaag gcccaaacag tgtcaccaag ctgaagtaca cgggtcacca tgatataacc
    19201 tggtaccaaa ccagcgttga acaacatact gagaaggacg aagatggtaa aaaatctgcg
    19261 atacttaaag gttgtccgtg aaatagcgta ggcataggtt gttgtgataa agacatttgt
    19321 caatgtccca actacggtta caaagacaga gatgaagagg gcttgtagga ttttatcctt
    19381 aaactgtgcc aaaaactcaa aaccgtctaa gccaaattgg gatgggaaga agctatagcc
    19441 gtattggagg aggcttttct cgtctgtcac tgaaataatg ataacgaata caaaaggtag
    19501 gatacaagag agggcaatca aacccgaaat gatactgaag aagatatctg ctttcttact
    19561 gaaggagtga atgccgacat tatcaatttt ttctttttta attttctttt ttgccatatt
    19621 ctcctccttt ctagaacaaa gctgagtttg gatcgactcg tcttgcaagc aagtttgata
    19681 ggataaccag aatcaaacca acaacggatt ggtaaagacc ggctgctgca gccataccga
    19741 tatctgctgt ctgagtcaaa ccattaaaga catatacgtc caaaacgttg gttacattgt
    19801 aaagctgacc agcattgtgt gggatttgat agaagagacc gaagtctgcg cggaagatat
    19861 ttccgactgc aaggatggtc aatacagtta caagcggagt caactgagga atggttacgt
    19921 tgcgaatacg ttgccacttg ctagctccgt ccactgtcgc tgcttcgtag taggttggat
    19981 caattcccat gatcgtcgca tagtacatga cactgctata tccaaagcct ttccaaatac
    20041 ctaggaaaag taggagatag ggccagatgc ccaggtcagc gtaaaaattg acttctttga
    20101 gaccaagact ttccaataga tgattgaaca cccctttatc aatatttagg aaggcatctg
    20161 taaagaaact gatgataacc caagacaaga agtaagggaa caacatagaa gtttggaaaa
    20221 tcttcaccat tctcttagaa cggagctcgc tgaggataat ggcaatccct acagatacaa
    20281 ctaaacctag aaagataaag ccaagattgt agaggacagt atttcgtgtg ataataaagg
    20341 cgtctcttga actaaataag aatctgaaat tatcgagtcc gacccattta ctatttatga
    20401 tactatctat gaaaccatta ctggtcatgt ggtagtcttt gaaggcaacc acgttcccaa
    20461 atactggaat gtaaaagaat agaatcaacc agagtgcccc tggcaaaacc atcaagagaa
    20521 agatccagtt gtctctcaat gtttttgaaa actttttcat aatttcctcc ctttttattt
    20581 tgatatccat ctaaaaattc ttttttagac ttttgataac gattacatta ttagtatact
    20641 cctatttgca ggttaggtta aactcctaat tatagaaaaa actccacaaa ttatgtagca
    20701 gatttaaaac tttatcacca ctatcaaaca aatgtcctaa atcaattgtt tattttatct
    20761 ctattagccc agtgatggcg tcactctgtt ataagcatcc aacaacgggg tatactgaaa
    20821 aatctccaga ctagggaact cagcgatagt tcctaatctg gagattttta atatgttatt
    20881 aggcgtttgc tttcaactta gcaataacct ctttaagatt atcaatcaac tctgctgcag
    20941 tatgctcaga gcctttttca tctgccaaga acaaaactgc tttttgaagt tcttcttgag
    21001 agttttcaag gacatcctta tctactgttt caaggtttga gtctttaaga agtttactta
    21061 attccttggc taatttcttg agtttgattt gcagactcat cttctcctgc tgtttctttg
    21121 cccgctgttt gtcctccatc cttagttgct gactggcttt ccttaatgga ctctagggaa
    21181 gcaatggcat ctttgactgt ttgcaagata tcacgtaaac cttgctctat caaactatca
    21241 tctgcaaaag ctttcttagc ctctgccaaa accagaggtg ctgaatctgt ggtaggattc
    21301 gatacacctg tcaatgatct caaaagattt tctaaggttt gagtctgctt actaatacta
    21361 gactaaaatc aaaaagcatt atataacagt gatatgaaat caactaaaga agaaatccaa
    21421 accatcaaaa cacttttaaa agactctcgt acagctaaat atcataaacg ccttcaaatc
    21481 gttctatagt aaa
//
LOCUS       DAVMAH010000037        20628 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVMAH010000037 DAVMAH010000000
VERSION     DAVMAH010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20628
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.037"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            21..1796
                     /locus_tag="VYO94_001381"
     CDS             21..1796
                     /locus_tag="VYO94_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
                     /protein_id="HEV1760013.1"
                     /translation="MANNRKTETLGVSYLSTFIDKHELLQSYFESNDKTPVWDGEIHV
                     LKSPSEKKDEILGKVPVQIKTTRQKKDVLKSFSLDTRDLELYKPNGGVVLFVVWLNED
                     NGLRDIYYKSLPPLSIKNLLKKSKLKNKSTNRKKLSIEIFKLDEKKMYPMLVDFINNS
                     QKQYSFINVEGISVEDIPDDKTLKFYFYGQEKEEIFNYQEEHDLFIYYLDPITGIEIP
                     LENTIKIVETEEETDLIIKIGDYVFQDVKRHRFPDGSVQLHFGESFTMSFDIKKKQFK
                     FNYTRPDLLSKAIKCTQVFQELGKIGYFTLNGNKIELDERSIKDISSLDLEADIKGLL
                     KISNFMKKMGIQKDVDLSCFDKQSQRNLNILYSGLVLKKKVALNYNESKLLHLNIANI
                     HIITLYSFLSDKNGTMIDIFTETPWCREGETEDEDYLDISIFEVFEPNDWLKIDNCKI
                     DSVIASYQRLVDNKLKYEGADRTILKIVIAADMAEDKTKRELLLNWAQCLSDWNLKYS
                     KNCEMAIINDLQIKSRVRKLNSKETETLTNILVNSNDNYELCFGSSVLLKSKPQADLF
                     WNKLDNETKERYKDFPIYTLYMKLS"
     gene            complement(2007..2813)
                     /gene="yidA"
                     /locus_tag="VYO94_001382"
     CDS             complement(2007..2813)
                     /gene="yidA"
                     /locus_tag="VYO94_001382"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV1760014.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMADKEIVKCMFIDEPE
                     ILDATIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(2826..4130)
                     /locus_tag="VYO94_001383"
     CDS             complement(2826..4130)
                     /locus_tag="VYO94_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1760015.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            4202..4579
                     /locus_tag="VYO94_001384"
     CDS             4202..4579
                     /locus_tag="VYO94_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV1760016.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            4670..5002
                     /locus_tag="VYO94_001385"
     CDS             4670..5002
                     /locus_tag="VYO94_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV1760017.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            5014..6585
                     /gene="ffh"
                     /locus_tag="VYO94_001386"
     CDS             5014..6585
                     /gene="ffh"
                     /locus_tag="VYO94_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV1760018.1"
                     /translation="MAFESLTERLQNVFKSLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(6780..8063)
                     /locus_tag="VYO94_001387"
     CDS             complement(6780..8063)
                     /locus_tag="VYO94_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV1760019.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(8415..9128)
                     /gene="rsmG"
                     /locus_tag="VYO94_001388"
     CDS             complement(8415..9128)
                     /gene="rsmG"
                     /locus_tag="VYO94_001388"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV1760020.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            9222..9782
                     /locus_tag="VYO94_001389"
     CDS             9222..9782
                     /locus_tag="VYO94_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV1760021.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            9784..10683
                     /gene="htpX"
                     /locus_tag="VYO94_001390"
     CDS             9784..10683
                     /gene="htpX"
                     /locus_tag="VYO94_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV1760022.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALVSAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(10832..12391)
                     /locus_tag="VYO94_001391"
     CDS             complement(10832..12391)
                     /locus_tag="VYO94_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1760023.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEICSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(12630..12947)
                     /locus_tag="VYO94_001392"
     CDS             complement(12630..12947)
                     /locus_tag="VYO94_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1760024.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            13117..13659
                     /locus_tag="VYO94_001393"
     CDS             13117..13659
                     /locus_tag="VYO94_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV1760025.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            13659..14288
                     /gene="nth"
                     /locus_tag="VYO94_001394"
     CDS             13659..14288
                     /gene="nth"
                     /locus_tag="VYO94_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV1760026.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            14499..15020
                     /gene="pyrR"
                     /locus_tag="VYO94_001395"
     CDS             14499..15020
                     /gene="pyrR"
                     /locus_tag="VYO94_001395"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV1760027.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            15039..15962
                     /locus_tag="VYO94_001396"
     CDS             15039..15962
                     /locus_tag="VYO94_001396"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV1760028.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            16012..17091
                     /gene="carA"
                     /locus_tag="VYO94_001397"
     CDS             16012..17091
                     /gene="carA"
                     /locus_tag="VYO94_001397"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV1760029.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            17404..20580
                     /gene="carB"
                     /locus_tag="VYO94_001398"
     CDS             17404..20580
                     /gene="carB"
                     /locus_tag="VYO94_001398"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV1760030.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDTLIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIKSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCHGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         6177 a         3852 c         4529 g         6070 t
ORIGIN      
        1 gttattttag aggtgcagat ttggccaata ataggaaaac tgagacatta ggtgtttcat
       61 atctttcaac atttatagat aagcatgagt tacttcaatc ttattttgaa agtaatgata
      121 aaactccagt atgggatgga gaaattcatg ttcttaaatc accgagtgag aagaaagacg
      181 aaatattagg taaagtacct gttcagatta aaactactag acagaaaaaa gatgtgttaa
      241 aatccttctc attagatact agagatttag aactatataa accaaatggt ggagtagttt
      301 tatttgtagt ttggttgaat gaggataatg gtttaagaga tatttactat aagtcattac
      361 ctcctctttc tataaagaat ttgctcaaaa agagtaaact aaaaaataaa tctacaaata
      421 ggaagaaact ttccatagag atttttaaac tggatgagaa aaaaatgtat ccaatgttag
      481 tggatttcat aaacaatagt cagaagcagt atagtttcat aaatgtcgaa ggtatttcag
      541 ttgaggacat tcctgatgat aaaactctaa agttctactt ctatggtcag gaaaaagaag
      601 aaatttttaa ctatcaggaa gaacatgatc tctttattta ttatttagat cctataactg
      661 gcatagaaat acctcttgaa aacacaataa agattgtaga aactgaagaa gaaacggatt
      721 taattataaa aataggcgat tatgtttttc aagacgtaaa aagacatcgt tttcctgatg
      781 ggagtgtaca gcttcatttt ggtgaaagct ttacaatgtc ttttgacata aagaagaaac
      841 aattcaaatt taactatact aggccggatt tgctgtcaaa agctataaag tgtactcagg
      901 tatttcaaga gctaggaaaa atcggatatt ttacccttaa tggtaataaa atagagttag
      961 atgaacggtc aataaaggat atttcttcac ttgatttaga ggctgatata aagggattgt
     1021 taaaaatttc taactttatg aaaaaaatgg gtatacaaaa agatgttgat ttatcttgct
     1081 ttgataaaca atctcaaaga aatctaaata ttctttattc aggtcttgtc ttaaaaaaga
     1141 aagttgcttt aaattataat gaatcgaaat tacttcacct aaatattgct aacatccaca
     1201 ttataacttt atatagtttt ttgtcagata aaaatggaac tatgatagac atttttactg
     1261 aaactccttg gtgccgggaa ggagaaactg aagatgaaga ttatttagac atttcaattt
     1321 ttgaagtatt tgaaccaaac gattggctaa aaattgataa ttgtaaaatt gattcagtta
     1381 ttgcctcgta tcaaagattg gtagataata agctgaaata tgaaggcgct gaccgtacta
     1441 ttttaaaaat agttatcgct gcagacatgg cagaagataa gactaaaaga gagttgttac
     1501 ttaattgggc gcaatgtctt tctgactgga acttaaaata ctcaaaaaat tgtgagatgg
     1561 ctataataaa tgaccttcaa ataaaatcta gagttcgtaa attaaacagc aaagaaacag
     1621 agacactaac taatatttta gtaaatagta atgataacta tgaactttgt ttcggttcat
     1681 cagtgctatt aaaatcgaaa ccacaagctg atttgttttg gaataaactg gataatgaga
     1741 caaaagaaag atataaggac tttcctattt atactttgta tatgaaatta tcgtaaaatt
     1801 aaaagagatt ataaagagat aacatataga aatagagagt gatttattac aattcagtac
     1861 cacaaattaa gaaagcaatg cctatttttt gtactctcaa gatttaagta actgtacaac
     1921 tgcaattaaa tttattaatt tactctcatt gtgatatatt catacaaaaa ccgctcagct
     1981 gagcggtttt agtctattct ttccttttac agtacccatg ttcggatggc gtgggcaacg
     2041 ccggattcgt catttgtttt agtgatgtat ttggcgattt ttttgatttc tggatttcca
     2101 ttttccatga caacggggtt tccaacgact tccagcatgg cacggtcatt ttcttcgtca
     2161 ccgattgcca tggtttcatc tttggtcaat ccgagttttt cagccaagtg agtaatggct
     2221 gaacccttgt ctacattctt tgtaaggagt tcgaggtaga aaggagcaga tttgttgatg
     2281 gagtagcgct cgtaaaattc tgctggaatt ttttcaatcg tagcatcgag gatttctggt
     2341 tcatcgatga acatacattt gacaatttcc ttgtcagcca tttcttcagg tgtacggtag
     2401 aagataggca tgctgacgag ggttgattcg tgcacagtgt attttccgat attgcgattg
     2461 gcagtataga taccgtcctt ggtaatggcg tgcatgtgga caccgagctt gcggctgaga
     2521 aattccatat ctagataatc ctcataagtc aaggattcgc tgataatctc atgtcctgta
     2581 gcagtttctt ggacaagggc accgttgaag gttaccacat agtccccctc gtctctcaac
     2641 tgcaagtcgt ctagaagttt ggcaacgcct gcgatagggc ggccagttgc aatcacgact
     2701 ttgacaccag cttctttggc atcttggatg gcagaaaaga cttcaggagt gatttccttt
     2761 tggctgttga ctagggttcc gtcaatatcg acggcgatta gtttaatact cataaatttc
     2821 ctcttttagt ttttatttgg ggtaaaatga tcgttctcaa tcaagtgtaa aaattgctgg
     2881 gtgatgcttg cgaagatgct gttttggtct aacatttctt tcgggaaata aaagcgatta
     2941 tctccgtggc gacttccagc aagggattgg acgatagggg acaggctaga gagttctgcc
     3001 agttctccat ttttttgtaa aatctcaatc tgtgtccttg gattttcaga ttcgggacgg
     3061 taaatatcat aagggaggtc aaagttctta tgaatggcag tatagtagtc gggatcaaag
     3121 ccgatgtcct caaccaattt tctcatgcta gcgagttggt cttggtcttc ttgtgaaaag
     3181 gtaatggatt taaagacctt gcggttgaca aagcgatgcg ataaatctgc aagaatcttg
     3241 tcaggactgg tcatccagag ttggaagtag gtattcatca caccatcatc cagagccaga
     3301 tagtcagtca aggtcacatt tttttcgaag aaaggcagga ggtgtggaga agttcgggca
     3361 aagaaatcct tgtcctcagg atagagttcc ttggcgcgtt tgagaagatt ctgtaggaga
     3421 acttccatgg cgcgtgttgc ggggtggaaa taaacctgca tgtacatctg gtagcgactg
     3481 aggacgtagt cttcgatggc gtgcatgcca ttgcgctgaa aggcgatacc attttcgata
     3541 ggacgaatga ctcggaggat tcgagtcagg tcaaattccc cataggatgc tcctgtaaaa
     3601 taggagtcgc gcaagagata gtccatgcga tctgcgtcaa tctgactaga aatgagctgc
     3661 acgacctgct tgttaggata ggtatggtct atgacactgg caactttctc tggaaaatcg
     3721 ggcgctactt gtagcaagac ttggtgaatc tctgtctcag gattttgaat aatctcctga
     3781 gtaatggctt catggtctgt atcaaagaga ttttcaaaag tatgggagta ggcaccatgc
     3841 ccaaggtcgt gtaggagagc agcggtcatg gtcaagagag actcggcagg attccattcc
     3901 tcaggatatt tttcttcgaa aatctctgtg atgcgtcgtg caatttcata gactcctaga
     3961 cagtgagaga agcgactgtg ttctccaccg tggaaggtat aactggaagt tcccagttgt
     4021 ttgatccggc gcaaacgctg aaattctttt gtattaatca agtcatagat gatttgatta
     4081 ttgacatgga tgtagttgtg aacagggtca cggaatactt tttcgttcat atgaccatta
     4141 tagcaaaatc ctgctctttt tggtaaaata gtaggacaag agacaagaaa gagggcctga
     4201 tgtgaagatt cggatgcgaa atacaattca gtttgatgag cagttggaag tgattgacca
     4261 gctttatgat gtggaagtgc atgaaaaagg agattatagc tacctgcttt tctataatga
     4321 ggaaaaggaa aaagtagtga ttaaatttca tggtcaagaa cttatgatga gccgattttc
     4381 taatcccaag accattatgc gctttctaaa ggatagcgat agtttagcct atattcctac
     4441 acctatgggc atgcaggagt ttatcatcca aacgagccat tatcaagttg ataggcaaaa
     4501 gattgaacta gattatcaac tacaaaatca agagggacat ccttttgcca gctatcaatt
     4561 ggaaattact tggggctagg ctcatgtctt tttcaaattt agctatctat cttcttggat
     4621 cggcttccta gtgtggtaga ttaggctaat ttttggtata ataaaagtta tggaaatcga
     4681 aaaaaccaat cgtatgaatg cgctctttga attttatgcg gcgcttttga cagataagca
     4741 aatgaattat atcgagctct actacgctga tgattacagc cttgctgaaa ttgccgagga
     4801 gttcggtgtc agtcgtcagg ctgtctatga caatatcaag cgaacagaaa agattctgga
     4861 agattatgag atgaaattgc acatgtactc ggattatatt gtccgcagtc agatttttga
     4921 tcagattttg gagcgctatc ccaaggataa ctttctgcag gagcagatag aaattttaac
     4981 aagcattgat aatagagaat aagaggaaga aaaatggcat ttgaaagttt aacagaacgt
     5041 ttgcagaacg tctttaaaag tctacgtaaa aaaggaaaaa tctctgaatc tgatgtccaa
     5101 gaggcaacca aagaaattcg cttggccttg ctcgaggccg acgttgcctt gcctgttgta
     5161 aaggacttta tcaagaaagt tcgtgagcgt gcagtcgggc atgaggtcat tgatacactt
     5221 aatcctgcgc aacagattat taaaatcgtt gatgaggaac tgacagctgt tttaggttct
     5281 gatacggcag aaattatcaa gtcacctaag attcctacaa tcatcatgat ggttggtttg
     5341 cagggagctg gtaaaacaac ttttgcaggt aagctggcta acaaactcaa gaaggaagaa
     5401 aatgcccgtc ctttgatgat tgcggcggat atttatcgtc cagctgccat tgaccagctt
     5461 aagaccttgg gacaacagat tgatgtgcct gtctttgcac ttggaacaga agtaccagct
     5521 gttgagattg tacgtcaagg tttggagcaa gcccaaacta atcataacga ctatgtcttg
     5581 attgatactg cgggtcgttt gcagattgat gagctcctca tgaatgagct tcgtgatgtg
     5641 aaagcattgg ctcaaccaaa tgaaatcttg cttgtcgttg atgctatgat tggtcaggaa
     5701 gcagccaatg ttgcgcgtga gtttaatgct cagttggaag tgactggggt catccttacc
     5761 aagattgatg gcgatactcg tggtggtgct gctctgtctg ttcgtcacat tactggaaaa
     5821 ccaatcaagt tcactggtac aggtgaaaag attacggaca ttgaaacctt ccacccagac
     5881 cgcatgtcta gccgtatcct tggtatgggg gatatgctca ctttgattga gaaagcttct
     5941 caggaatacg atgaacaaaa agcccttgaa atggctgaga agatgcgcga aaacaccttt
     6001 gattttaatg atttcatcga tcaattagat caggtgcaaa atatggggcc gatggaagac
     6061 ttgctcaaga tgattccagg tatggccaac aatccagccc ttcaaaacat gaaggtggat
     6121 gaacgccaga ttgctcgtaa acgtgccatt gtgtcttcga tgacacctga agagcgtgaa
     6181 aacccagatt tgttaaatcc aagccgtcgc cgtcgtattg ctgctggttc tggaaataca
     6241 ttcgtcgaag tcaataaatt catcaaggac tttaaccagg ctaaacagct catgcagggt
     6301 gttatgtctg gggatatgaa taaaatgatg aagcaaatgg ggattaatcc aaataacctt
     6361 cctaaaaata tgccaaatat gggaggaatg gatatgtctg cccttgaagg aatgatggga
     6421 caaggcggta tgcctgactt atcagctctc ggaggagcag gaatgccaga tatgagccag
     6481 atgtttggtg gcggtttgaa aggtaaaatt ggtgaatttg ccatgaaaca gtccatgaaa
     6541 cgtatggcta acaaaatgaa gaaagcgaag aagaaacgca agtaagacaa gagattgatg
     6601 caaatctcat ttgatgagaa aataaagtaa aaatttctat gataaaacgt acagtatcaa
     6661 ggttttagaa tatctgatat tatacgtttt ttgattttaa taattttgtt aagacacttt
     6721 tattatggta tgcgaaaaat ccactcagct gtctgagtgg attaggtgta tttagactct
     6781 tagtctttat tttcgtatgg caagatcaag ttcaagatga ttcctgtcat ggctgaaagg
     6841 gcagtacctg aaagtgtaac tggaccaagt ttaaggatag ctcctccaag tccaagaacc
     6901 aacatagcac ttgcgatgat gaggtttcgc atttgagcga aatcaacacg ttctttaatc
     6961 aagactttca aaccattgct ggcgataacc ccatagagaa ggattgacat accaccaagt
     7021 acagcgtttg gaatagttga aatcaaggca gtgaatttac caaggaagct gagggcaatc
     7081 gcgatgaagg cagcgttacg gataactgag acagaagcga tacgagtcat accgataacc
     7141 cctgtatttt ctccgtaagt tgtattggct ggtccaccaa ggaaggcaga aacagaagtt
     7201 gcgataccgt caccaagaag agtacgatga agacctggtt cttttaagaa ttgacggcca
     7261 cagatttgac ccaaaacagt atggtctccg atatgttcag aaattgttac gatagcgatt
     7321 ggcaagatag cgatggcttc tggaccaaag taaagattgt actctttaaa ggcaccacct
     7381 gtgctaaatg gcaagtagaa accaggaatt tcgaaccagt tggctttaag aactggtgta
     7441 aagtcaacca agccaagagt tagtgcgaaa aggtaaccac cgataatggc aaagaggaat
     7501 ggaatgattc gtaggaagcc ttttcctttt gtattgataa aggcagcaat taggaaagta
     7561 acaacggcta ccagagcatt tttccaattt ccgtctgcta caagacctgc attggtaaca
     7621 gctgaacctg caagtccaag accgataacg atgatcatag gaccgataat gattggtggc
     7681 aagagtttat caatccattt tgttcctaca aatcggatgc tggtagcaac aaggacatag
     7741 accaaaccag tcaagataac ccctgtttgg gcagcagata catcaccccc catttctttc
     7801 atagccagtg acatagctgt gataaaggca aatgaagaac ctagataaac tggaacttta
     7861 aaaccagtag caatcatgta gatgagtgtt ccaacacctg aagcaaaaag ggcaacagat
     7921 acaggcattc ccaaaatcaa tggtaccaag atggtcgcac caaacatggc gaaaacgtgt
     7981 tggaagctaa ggagaattcc ttttccatcc gaaggacgtt ggtcaacgtc tagtaacaaa
     8041 tcaacagttg attcttgttt catataaacc tcacttttgg gcatcagaaa agagcccatt
     8101 attttacagc aataggccct cagagtaaga cttctctaaa atctagactt taaagagttt
     8161 caaatatttt tgcgtcttcg tcacctcacg ggatgacatt aaaaaccttt gcttaggata
     8221 gtatagcaga aaaaaatgat tttgtaaatc attttttccc gagcctagaa ataaaagagc
     8281 gaggctgatt ttgtaaatca ttttttcccg agcctagaaa taaaagagcg aggctgattt
     8341 tgtaaatcat tttttcccga gcctaaaaat aagagagcga ggttgatttt gtaaatattt
     8401 ttttacttaa aaatttaaag cgggcgttta tttggcatac cagccttacg tggatattta
     8461 tttggtgttt cttttttctt ttctaccact gtgatgtaac gcggatctct atttggtagg
     8521 gcgtagctga gattgtcttc gactttacta aaaaggagat tgagggcatt cttagcttct
     8581 aacaactcct caggcgcatt gctggccttg agtgccaata gttttccacc aaccttaagg
     8641 tagggaatag tcaattcaga taggacctgc atacgggcaa ccgcacgagc tgttacaaaa
     8701 tcatattgag cacggaagtt cttgtcttgg gcaaaatctt cggcacgtcc gtggtagaaa
     8761 tgaactccgt tcaaatccag ttcttgagcc aagagttgta ggaagttgat gcgcttattg
     8821 agtgaatcaa taatggtcac atctaactcc ggatagagaa ttttcattgg tagactagga
     8881 aatcctgccc cagccccgat atcaagaagt ttgatagttt cattgggaat caaaccttga
     8941 agaatgggtg caatcgaatc gtaaaaatgt ttgagataaa cttcttcctt gtccgtaatc
     9001 gccgtcaaat taatcttctc attccactcg accaagagct caaaataacg ttcaaattgt
     9061 tctttttgct ggttcgaaag tggaagattc tgctcggcaa gcaagttgta aaatgtttct
     9121 ggtttcatag ttatttcctt ctttagtatc atcttatttt accacaatca ttaaaaattt
     9181 gatatactgg tactaatcta aaagtagaaa ggacttatat catgacttgg attattcttg
     9241 gagttatcgc tcttattgtt atttttgtga ttgttagcta taacggtttg gttaaaaatc
     9301 gtatgcaaac caaggaggct tggagtcaga ttgatgttca gttgaaacgt cgcaatgatc
     9361 tcttgccaaa cttgattgag actgtaaaag gttatgccaa atatgaaggt tctacccttg
     9421 aaaaggtggc agaactacgt aaccaagtgg cggcagcgac ttcaccagca gaagctatga
     9481 aagccagtga tgccctcact cgtcaggttt caggtatttt tgcagttgca gaaagctatc
     9541 cagatttgaa agctagtgct aactttgtta aattgcaaga ggagttgaca aacacagaaa
     9601 ataaaatttc ttactctcgt caactctata acagtgttgt cagcaactac aatgtaaaat
     9661 tagaaacttt cccgagcaat attatcgctg gaatgtttgg atttaaagcg gcagatttcc
     9721 ttcaaacacc tgaagaggaa aagtcggttc ctaaagttga ttttagcggt ttaggtgact
     9781 aagatgttgt ttgatcaaat tgcaagcaat aaacgaaaaa cctggatttt gttgctggta
     9841 tttttcctac tcttagctct tgttggttat gcggttggtt atctctttat aagatctgga
     9901 cttggtggtt tggttatcgc actgattatc ggctttatct acgctttgtc tatgattttt
     9961 caatcgacag agattgtcat gtccatgaat ggagcgcgtg aggtggatga gcaaacggca
    10021 ccagacctct accatgtagt ggaagatatg gctctggtcg ctcagattcc tatgccccgt
    10081 gttttcatca ttgatgatcc agccttaaat gcctttgcga caggttctaa tcctcaaaat
    10141 gcggctgttg ctgcgacttc aggtctacta gctatcatga atcgtgaaga actagaagct
    10201 gttatgggac atgaagtcag tcatattcgt aattatgata tccgtatttc gactattgca
    10261 gttgcccttg ttagtgctat caccatgctt tctggtatgg caggtcgtat gatgtggtgg
    10321 ggtggagcag gtcgcagacg aagtgatgat gaccgagatg gaaatggtct tgaaatcatt
    10381 atgctagtgg tttccctact agctattgta ctggcacctc tcgctgcaac cttggttcag
    10441 ctcgctattt ctcgtcagag ggaatttctg gcagatgcat ctagtgtcga gctgactcgc
    10501 aatccccagg gaatgattaa tgccctagat aagttggaca atagcaaacc tatgagtcgc
    10561 cacgtcgatg atgctagcag tgctctttat atcaatgatc ccaagaaagg tggggggttc
    10621 caaaaactct tttataccca cccacctatc tcagaacgga ttgaacgttt aaaacagatg
    10681 taaaatgaag gctggaaaaa agtctttaaa atctgaaaaa cgcataatat caggtgtgaa
    10741 aacttgatat tatgcgtttt actatgggaa gatttacttc tttttctcct aaaattgtgt
    10801 ttttgcccca cctatctgct atgttgcaaa tttataaatc ttctaaatta actagcttca
    10861 aaccgtgttc tgtcatgcga tagatgatcg agcagatttc ttttaagaaa cgacggtcat
    10921 gcgaaacagt gatgagaccg cctggatagg ttgcaaagag ttttctgatt tggggttgag
    10981 aagtgggaga aaagtttcgt gtgggttcat ccagcaggag aaagtttggt ttgcgcagga
    11041 ctaaatccaa aagcaggagt tttccctgtt gtccgccaga taaggagcga atttgatgct
    11101 gcatttctgg ataactgaaa ttgagactgg ctaggtgaga ttggattttc tgaagttcct
    11161 ctttttcccc agttttgctg atataagcta ttggtgataa atccaattgc agttttttgt
    11221 ggtaatcttg tggcataaaa ccaagggaaa tctctctttt atcattcaga agttgcttta
    11281 atttggctaa cagagttgat ttcccaacac catttggccc gataataccg attttttctt
    11341 gcccacggac agttagttgt agtttttgaa ccaaaactcg gtcgtcaatg gacaaatttt
    11401 ctttttccag ttggactaag actttagaag ctggtaatgg ttggatgtct gaaaagaaaa
    11461 gttggatttg ttcctcttca agtggctttt gagtcatgga ctgagctgtc ttttcgtagc
    11521 gtttttcttg tgagaggaca gttttcatct ttttagccaa taggcgaccg gcagtactat
    11581 ctttggtagc tcgaagcgca gtttctacat tttgcttaac tctccgatgt ttttccatgg
    11641 ttttatcgta ggctctttgg ttgttagcag cttgctgact ttgtttggca aaattagcct
    11701 ttctctgctc actatagcta tcatagtcta aatgctctac tagcgtttcc gcttctttac
    11761 ggtgtttgac cagtcgcaag tgaacaatag tgtctgctgt ttcagaaaga aagtcttcat
    11821 catgggaaat gaaaataacg gtttgcctgg tcttttgaat ctggcctttt agccaatcaa
    11881 ctgtctcaag gtctaggtca tttgaaggtt catctaaaaa tagaatctca aagggtttgg
    11941 ctaactcatg gataagctga attttcaaag cttctccccc tgatagattg ccaatctttt
    12001 ggtcacttgc gaaacgattg ctatcaaaat gcaattcctc cgccaaacga tagaggatac
    12061 tgtagtctaa atcaatagaa tctaaaaaga aatagtcgtg taaagttttc tttttcagct
    12121 cctcgggaag tttttgagga atgtaggcca gtgactgata gtcagattgg atgtttccct
    12181 tgatagtgaa atcagacaaa gcttccccca ttaaaatttt aagtaaggtt gatttgccat
    12241 ttccttcttc accaataata gcaacctttt ccccgtcttg gatggtcatg cttaggtcag
    12301 atacaagatc tcgtaaatct ttgttttgtg tgatggttag atgattgatt tttatcatat
    12361 gatttccctt tctagaatgt tcatagtgca taacaaaaag ctctacttta cctagtagag
    12421 cccaaagtct atgtcaaaaa aactctatta acatgccaga aaaagagcat aaaagagcac
    12481 acaaaaagag acaaaaacaa gatctactaa ataaaggttc tttatttgat agacttagtt
    12541 gttcatgtct cccttacctc cgagtattag tatctttata ttataccttt aaggaaattt
    12601 tgtcaacaga aaactggaaa ttctatgctc taaaatccaa aaacaggtcc atagagactt
    12661 agtacgtgtt tgacatgctc gtaatggaat ttatcatagt ttcgccaagc agtgcgtgct
    12721 tgatcgttta gttttaggct acccagtcca atcagaagac tggtgggttg gtaaaatttc
    12781 tcaagatcaa ttaagatact gttgttcaac ttttccgttt ttttgagctc ttgcatagta
    12841 gtgtttagca gctcttgtag tcgaatatca tctgccgtac cctgtttaca gttttggtag
    12901 cttttattta acttggatag gagttgaatg agtttcttgt cttccatgtg agcatcctcc
    12961 ttgatctgat gtactctttc cctatagtat agcactaaaa aacaaaactg tcatagtaaa
    13021 tatgttaaaa ttctgaattt taattacaaa gtttggtgtg ctgatttgta gccttttcat
    13081 ggtataatca agagagtaaa tctttatgga ggaagtatga aattaaatat tcaagaaatt
    13141 cgtaagcagt ctgaaggttt gaactttgaa caaacgttag atttagttga tgacctgcgt
    13201 gcacgtaatc aagaaatttt agatgtaaaa gatatccttg cagttgggaa agtacaatat
    13261 gaagaccgta tgtatttctt agattatcaa ctatcttata ccattgttct tgcttcgagt
    13321 cgcagtatgg agccagttga gttagttgaa tcttatccag tcacggaagt tttcatggaa
    13381 ggcgcaacta accatctaaa tcaagaaatt ttagatgatg acttggtctt gcccatcgaa
    13441 aatgaggcgc ttgaccttgc tgagagtgta tcagacaata tcttgctaaa cattcctatc
    13501 aaggtcttga cggctgaaga agaagctggt caaggatttg tctcaggaaa tgactggcaa
    13561 atcatgacag aggaagaata ccaagctcaa caagcagtaa agaaagaaga aaacagtcct
    13621 tttgctggct tacaaggact atttgacgga gatgaataat ggtcttgtca aaaaaacgag
    13681 cacgaaaggt gctagaagaa atcattgccc tcttcccaga tgccaagcct agtcttgatt
    13741 ttaccaatca ttttgaactc ctggttgcgg tcatgttatc agcccagacg acagatgcag
    13801 cggtaaataa ggccacacca ggtctctttg ttgcctttcc aacaccccaa gctatgtctg
    13861 tagcgacaga gagtgagatt gcttcacata tttctcgctt gggattgtat cggaataaag
    13921 ctaaattcct taaaaaatgt gcccaacagt tactagacga ttttgatggt caagtccctc
    13981 agacacgtga agaattggag agtttggcag gtgttggtcg caagacagcc aatgttgtca
    14041 tgagtgtagg atttgggatt ccagcctttg cagttgatac tcatgtggag cgtatttgca
    14101 aacaccacga tattgtcaaa aaatcagcga cgccacttga ggtggaaaag cgggtcatgg
    14161 atatcttgcc gcctgagcag tggttagctg cccatcaggc catgatttat tttggaagag
    14221 ccatttgcca tccaaaaaat ccagagtgtg accagtaccc acaattatat gattttagca
    14281 atttgtaaga tgctacattg aaactttttg cttgatttta agcatgcttt gtgctatagt
    14341 aaatgataac taaatattcc tttaaacctg tcccgtgagg caggcaagga gcgcgataaa
    14401 gtagaagggt gaagtctata ctgtgtgcag tagggctcgc ttggctataa atttcaagtc
    14461 tccttgttta aggagacttt tctttttgga ggtttgtcat gaaaacaaaa gaagttgtag
    14521 acgaattgac cgtcaaacga gcgattacgc gtattactta tgagattatc gaacgcaaca
    14581 aagatttgaa taagatcgtc ttggctggta ttaaaactcg tggtgtcttt attgcccacc
    14641 gaatccaaga acgtttgaag cagttagaaa atctttcagt tcctgttgtg gaattggata
    14701 ctaaaccttt ccgtgatgat gttaaaagtg gagaagatac ttctttggtt tctgtcgatg
    14761 tgacagaccg cgaagttatc ttggtggatg atgtgctcta tacaggtcgt accatccgtg
    14821 ctgctattga taatattgtc ggtcatggtc gtcctgcgcg tgtgagttta gcagttctag
    14881 tcgatcgtgg acatagagaa ttgccaatcc gtccagatta cgttggaaaa aatatcccaa
    14941 ccagtcgttc tgaagaaatc atcgtagaga tgacagaact tgatgaccaa gacagagttc
    15001 tgattactga agaagcttag aaagttaaag gagtagccat gtcagaaaat caacaagcat
    15061 tgaaccatgt ggtgtccatg gaagacctca ctgtcgatca agtaatgaaa ttgatcaagc
    15121 gaggaattga gtttaaaaat ggagcccagc ttccctatga agaccatccg attgtttcca
    15181 atctcttctt tgaggattct acacggacac ataagtcctt tgaagtcgca gagattaaac
    15241 ttggattgga acgacttgac tttgatgtga agactagttc ggttaataag ggtgagacac
    15301 tttatgacac cattttgact ctgtctgctt taggagtgga tgtctgtgtg attcgccatc
    15361 cagaggtcga ctactataga gaattgattg ctagtccaac gattacgact tccatcatca
    15421 atggtggaga tggttcgggc caacacccta gccagagctt gcttgatttg atgaccattt
    15481 atgaggaatt tggccacttt gagggtctta aagttgctat tgcaggtgac ttggaccact
    15541 cacgcgttgc caaatccaat atgcagattt tgaaacgctt gggatctgaa ctctttttcg
    15601 ctggacctga ggaatggaga agtcaagagt ttgcagacta tggacagttt gtaaccattg
    15661 atgaaatcat tgatcaggtt gatgtcatga tgtttctccg tgtgcaacac gaacgccatg
    15721 atagtggagc tgtattttca aaagaagact accatgccca acatggcttg actcaagaac
    15781 gttacgatcg tttgaaagaa acagcaatcc tcatgcaccc agctccaatc aatcgtgatg
    15841 tagaaatagc agaccacttg gttgaagcac caaaatcacg gattgtccaa caaatgacca
    15901 atggtgtctt tgttcgaatg gcaatcttag aatccgtact agcgagtaga aacgccaact
    15961 aaaacacaag acgttaaaag acgccagtga gcgtccacga gaggtgaaaa tatgacaaaa
    16021 agaattctag tattagaaga tggcacagtt tttgaaggca aggccttcgg agcagatatt
    16081 gatgtaacag gcgaaatcgt ctttaataca gggatgaccg gctaccaaga atccattaca
    16141 gaccagtctt ataatggaca aatcttgacc tttacttatc ctttggtagg aaattatggt
    16201 attaatcgtg atgattatga atccattatt ccaacttgta agggagtcgt tgtttttgaa
    16261 gaagcgcgta gagctagcaa ctggcgcaac caaatgacct tggatgaatt tttgaaagcc
    16321 aagaaaattc cagggatttc aggaattgat acgcgtgctc ttaccaagat tatccgtaag
    16381 catggtacta tgcgtgcaac cttgacccat gttggggaca gtatggacca tgtgacggac
    16441 cagctccaag caacagtttt accgacagac aatatcaaac aggtttctac taaaacgtct
    16501 tatccagctc caggagttgg tttgagcgtg gtgctagtgg actttggtct caagcactca
    16561 atcctacgtg aactttctaa acgcaactgt aacgtgacag ttgttcctta ttcgacaacg
    16621 gctgaagaaa ttctccatct caatcctgac ggagttatgt tgtcaaatgg tccaggtaac
    16681 ccagaagacg ttccacaagc actcgacatg attcgcggtg tacaaggaaa aattccaatc
    16741 tttggtattt gtatgggaca ccaactcttt gcaatggcaa acggggctaa gacctataag
    16801 atgaagtttg gccaccgtgg attcaaccat gcggtacgtg aaatcgcaac aggacgagta
    16861 gacttcacca gccagaacca tggttatgca gtcagccgcg aggatttgcc agagcacttg
    16921 attattaccc acgaagaaat caatgacaag tcagtggaag gtgtgcgcca cagataccaa
    16981 cctgctttct ctgttcaata ccacccagat gcagctcctg ggccacacga cgctagctac
    17041 ctatttgacg agtttatcga gatgatggaa gtttttaaac aatcaaacta agaacgagta
    17101 aaagctcgtc ggagaattta tgtaactgaa cacggacgga aagctcagaa tgtagagaaa
    17161 ccaacttgga ttgtcaatcc ttccttgatt tcctaaaatt caatcgcttt ctattcgtcc
    17221 tttgtatctt atttaatgtc gccctgagag gcgacgaata gaaaggagaa gggagctccg
    17281 tatttgctga actgaatacg ggctacggac ggtgctaaaa agatagttat tcctagaact
    17341 gacagttctt cgtcataact cctattttag ctttgtccgc ttgacaccct taatatctta
    17401 tatatgccta aacgtactga tattcaaaaa attatggtga ttggttctgg tccgattatt
    17461 attggtcagg ctgctgagtt tgactacgct gggactcagg cttgcttgtc gttgaaagag
    17521 gaaggttatg aggttgtttt ggttaactca aatcctgcaa ccatcatgac ggacaaggaa
    17581 attgctgaca aggtttacat tgaaccgatt acacttgagt ttgtgacacg tattcttcgt
    17641 aaggaaggtc cagatgcctt gctaccaaca ctcggtggtc agacaggtct caacatggcc
    17701 atggaattat ctaaaaatgg tatcctagac gagcttggcg ttgaacttct gggtaccaaa
    17761 ttatctgcca ttgaccaagc ggaggaccgt gatctcttta aacaattgat ggaagagctt
    17821 gaacaaccca ttccagaatc tgaaattgtt aacacagtag aagaagcagt tgcctttgca
    17881 gcgacaattg gctacccagt catcgttcgt ccagccttta cccttggtgg tactggtggt
    17941 ggtatgtgtg ccaacgagaa agaattgcgt gaaatcactg aaaatggttt gaaattgtca
    18001 cctgttaccc aatgtttgat tgagcgttcg attgccggtt tcaaggaaat tgaatacgaa
    18061 gtgatgcgtg actcagctga caatgccttg gttgtttgta acatggaaaa ctttgaccca
    18121 gttgggattc acacagggga ttccattgta tttgcccctg cgcaaaccat gtcagactat
    18181 gaaaaccaaa tgcttcgtga tgcgagcttg agcattattc gtgccctcaa gattgaaggt
    18241 ggatgtaatg ttcagctagc tcttgatcct aacagcttca agtattatgt tatcgaagta
    18301 aaccctcgtg tatcacgttc gtcagccctt gcttctaaag cgacaggata tccgattgct
    18361 aagttggctg ccaagattgc agtaggtttg accttggatg aggttataaa cccagttaca
    18421 ggttcaacct atgccatgtt tgaaccagcc cttgactacg tagttgctaa gattccacgt
    18481 ttcccatttg acaagtttga aaagggtgaa cgccgtctcg gtacacaaat gaaggcgact
    18541 ggagaagtca tggcaatcgg tcgtaacatc gaggaatctc ttctcaaggc ctgccgctcc
    18601 cttgaaattg gggtgcacca caatgaaata cctgaacttg cagcagtttc tgatgatacc
    18661 ttgattgaaa aggttgtcaa agcccaagat gaccgtctct tctacgtatc agaagccatt
    18721 cgtcgtggct acacacctga agaaattgca gagcttacaa aaattgatat cttctatctt
    18781 gataaactct tgcatatctt tgaaattgag caagaattgg gtgctcatcc acaagatcta
    18841 gaagttttga aaacagccaa acttaatggt ttttcagacc gtaagattgc tgaactctgg
    18901 ggaacgactg atgataaagt tcgccaactt cgcttggaaa acaagattgt tccagtttat
    18961 aagatggtag acacttgtgc ggcagagttc gattccgaaa cgccatattt ctattcaacc
    19021 tatggttggg aaaatgaatc tatcaaatct gataaagaat ctgtacttgt cctaggttca
    19081 ggtccaatcc gtatcggtca aggggttgag tttgactacg caaccgttca ctctgttaag
    19141 gctatccagg cagctggtta tgaagctatc atcatgaact caaacccaga gaccgtttca
    19201 acagacttct ctgtatcaga taagctttac tttgagccat tgacattcga agatgttatg
    19261 aacgtcattg acttggaaca accaaaggga gttatcgttc agttcggtgg tcaaacagcc
    19321 atcaaccttg cagagccatt ggcaaaagca ggtgtgacca tccttggtac acaggttgct
    19381 gacctagacc gtgccgaaga ccgtgacctc ttcgagcaag ctctcaaaga attggatatt
    19441 ccacagccac caggacaaac ggctaccaat gaagaagaag cagctcttgc agctcgtaag
    19501 attggcttcc cagttcttgt ccgcccatct tatgtacttg gtggacgtgc catggaaatc
    19561 gttgaaaacg aagaagacct tcgttcttac atgcgaactg ctgttaaggc tagtccagac
    19621 catccagttc ttgtcgactc ttatatcgtt gggcaagagt gcgaagttga tgccatttca
    19681 gatgggaaaa atgtactcat tcctggtatc atggagcata tcgaacgtgc tggtgtccac
    19741 tcaggtgact caatggctgt ttacccacca caaaccttgt cgcaaaaggt tcaggagacc
    19801 atcgcagact acaccaaacg cttagcaatc ggtcttcact gccatggaat gatgaacatc
    19861 cagtttgtta tcaaggatga aaaagtctac gttattgagg tcaatccacg tgccagccgt
    19921 accgttccat tcctatctaa ggtaaccaat attcctatgg ctcaagtagc gaccaagctc
    19981 attcttggtc aaagtttatc agaacttggc taccaaaatg gactttaccc tgaaagcacc
    20041 cgtgttcata tcaaggcacc tgtcttctcc tttaccaaac tagctaaggt agacagcttg
    20101 ctcggtcctg aaatgaagtc aacaggtgaa gttatgggtt ctgatgctac tttggaaaaa
    20161 gctctctata aagcctttga agcttcttat ctacacttgc caacttttgg taatgtcgtc
    20221 tttaccatcg ctgatgatgc caaagaagaa gccttgaact tggctcgtcg tttccaaaac
    20281 attggttatg gaatccttgc gacagaaggg acagcagcct tctttgctag tcatggcttg
    20341 caagcccaac ctgttggtaa gattggtgat gacgataagg atatcccaag ttttgtacgc
    20401 aaaggaagaa ttcaagctat cattaacaca gtaggaacaa aacgaactgc tgacgaagat
    20461 ggtgagcaaa ttcgtcgttc agccattgaa cacggggtgc ccctcttcac agcgctagat
    20521 acagctaatg ccatgcttaa ggtacttgaa agtcgtagct ttgttacaga agcgatttaa
    20581 atagaaaaat aagatatagc agactgaatt tagaacagta cacaggga
//
LOCUS       DAVMAH010000038        20341 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVMAH010000038 DAVMAH010000000
VERSION     DAVMAH010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.038"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(416..2143)
                     /gene="ezrA"
                     /locus_tag="VYO94_001399"
     CDS             complement(416..2143)
                     /gene="ezrA"
                     /locus_tag="VYO94_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV1760031.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2225..4171)
                     /gene="gyrB"
                     /locus_tag="VYO94_001400"
     CDS             complement(2225..4171)
                     /gene="gyrB"
                     /locus_tag="VYO94_001400"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV1760032.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4186..4749)
                     /locus_tag="VYO94_001401"
     CDS             complement(4186..4749)
                     /locus_tag="VYO94_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1760033.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4834..5388)
                     /locus_tag="VYO94_001402"
     CDS             complement(4834..5388)
                     /locus_tag="VYO94_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV1760034.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5399..6622)
                     /locus_tag="VYO94_001403"
     CDS             complement(5399..6622)
                     /locus_tag="VYO94_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1760035.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6659..9109)
                     /locus_tag="VYO94_001404"
     CDS             complement(6659..9109)
                     /locus_tag="VYO94_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV1760036.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLLEKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHRLKK
                     RFEKSEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9308..10237)
                     /locus_tag="VYO94_001405"
     CDS             complement(9308..10237)
                     /locus_tag="VYO94_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1760037.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDSYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10377..10664
                     /locus_tag="VYO94_001406"
     CDS             10377..10664
                     /locus_tag="VYO94_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV1760038.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10698..12032)
                     /gene="ciaH"
                     /locus_tag="VYO94_001407"
     CDS             complement(10698..12032)
                     /gene="ciaH"
                     /locus_tag="VYO94_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV1760039.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12022..12696)
                     /gene="ciaR"
                     /locus_tag="VYO94_001408"
     CDS             complement(12022..12696)
                     /gene="ciaR"
                     /locus_tag="VYO94_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV1760040.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12805..15351)
                     /locus_tag="VYO94_001409"
     CDS             complement(12805..15351)
                     /locus_tag="VYO94_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV1760041.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLCFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15474..15914)
                     /locus_tag="VYO94_001410"
     CDS             complement(15474..15914)
                     /locus_tag="VYO94_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV1760042.1"
                     /translation="MTPQEMWNKYKQINPSIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVKPFNRVSADHAYKEGE
                     GNKTLVYWRQVHEDFFRDCLGEAGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15889..16536)
                     /locus_tag="VYO94_001411"
                     /pseudo
     CDS             complement(15889..16536)
                     /locus_tag="VYO94_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
     gene            complement(16514..17014)
                     /locus_tag="VYO94_001412"
     CDS             complement(16514..17014)
                     /locus_tag="VYO94_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1760043.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17025..17723)
                     /locus_tag="VYO94_001413"
     CDS             complement(17025..17723)
                     /locus_tag="VYO94_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV1760044.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(17716..17952)
                     /locus_tag="VYO94_001414"
     CDS             complement(17716..17952)
                     /locus_tag="VYO94_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV1760045.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18052..18978)
                     /locus_tag="VYO94_001415"
     CDS             complement(18052..18978)
                     /locus_tag="VYO94_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV1760046.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19053..19868)
                     /locus_tag="VYO94_001416"
     CDS             complement(19053..19868)
                     /locus_tag="VYO94_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760047.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSIFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(19872..20192)
                     /locus_tag="VYO94_001417"
     CDS             complement(19872..20192)
                     /locus_tag="VYO94_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1760048.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6116 a         4463 c         3608 g         6154 t
ORIGIN      
        1 ctatttaccg tagactaaag ttgtacaaga aaagtgcaaa taagaaatct ccagattagg
       61 aactatccgt gagttctcta gtctggagat ttttcaatag acttcgttat tggacggtta
      121 ccaagttact caaagtacag atttgaagct gcagataaga ctgacgaaat cactttaata
      181 ctaaatgaaa atcaaaaagc aaactaagaa gctagcctca ggctgtactt gagtacggta
      241 aggcgacgct gacgtgattt gaaaagattt tcgaagagta taaaacactg ttttgaggta
      301 gtggataaat cggctgggca aaaactcaat ctcaggagaa aatgaagtaa atctccccac
      361 aactatagaa aaagatttga ttctgctcct cacacaataa aatctttttc ttttattaaa
      421 aacgaatcgt ttcacgtgtt ttctcatatg aggtaacaaa gcgattagtt acaccaggct
      481 ctgccacttc caatgcttga gaaatcttgt caaatgaagc gtgataatca aattcttttt
      541 caaaaatatc taaagcttcg ttaaatgctt cttgaatgcg ttcatcaaat gagcgatagc
      601 ggttagaata ttgcaagagt tgctctgtca aagttgcata ttgtacaata ttataagttt
      661 ccgtttctaa agcttccata tcattcgttg caatttcaag aactcgggta acagattcaa
      721 tgttaatcat tttttgttct aactcaacca ttaaatcctc ggtattattg cttgccgtaa
      781 agaataactt caagaaagtt tgtggaatac ctggcagatt gcgtttttcc atgtatcgct
      841 tgatagtatg gagacgattg acataaacat tggccttttg acgtgcatta atatcatctt
      901 tctcaatttg tgtcaggcgc tcactaactg aaatttgctc atcttcaata tcttttagtt
      961 gagtttgtaa atcctcaaga ttttcttcaa gaactgaata agcttgggtt ggttcttctt
     1021 gatttgaagt tacctcaaca atagctgcct caaaactctc taattctgtc tgaatacgac
     1081 gaacatggct tgcagctgtc tcaggaagta aataggtctt gttcaaacgt gcaatatctt
     1141 ctcccaataa agtattattc tctttcatat gttgaaggta agttggaaga gttgcaagta
     1201 gattttccac tactttctga gcagcaattt ctcgagtaaa aatatcatac aaggcattga
     1261 tttcctcttg tgcctgtcca ttctcatatt cggcattatc caattccaac tgacgaatat
     1321 tctcttggtt tttcttgaat gcttcataaa gcaagtggaa acgcgcttca atatccgttt
     1381 caacaaaatg ataattagca tcaattagtt tacgataacc ggcttccaaa tcctgtaatt
     1441 gatctggcaa ttctgtagaa agcgtcgtaa ccaaggctgg aacacgatcc acaatatgac
     1501 ttaaggccaa aatgtgattt tctgtattat ccaaaatcac tgcggcttcc acagggtcac
     1561 ccgatgaatt caaggttaca aattgtgaaa attcagattg gatattttct aattgttttt
     1621 caatttcatc caaggcttga ccatactgtt ctgaattttc agcaactcta tgctgaagtt
     1681 cctcaaataa atccaaagca tgaagaacac gaccactatt tttagattct tgcttctcta
     1741 agtctgccaa agcattgcga attgccgcaa tatcttcttc aatcaaagta atttgactct
     1801 caatttggtc aatttgatga ctggccttga gaaaacgaaa tgaatggtta tagccctctg
     1861 cttcaaagag attattttca atatcggcaa aagagttgag agataaatcg acccattttt
     1921 gattccattc acggaaagcc acttgacttt gtccaatcaa gtgcatattt tttacagctt
     1981 ctacttcatc atttactgga agattgtata gttcttcttt tctttcttct agtgcctcta
     2041 atctcccctc gtttcgctta cgtagaaaga ttgccactac ataagccaga actaaaatga
     2101 ctgcaattgc aaccattaaa taaattagtt gtccattaga catatcaaac tcctttttta
     2161 cttgaaacaa tcgtaacgat tatatcatat tttttagacc aagggaacta cttctcccta
     2221 ttttttagac atcaagtgta ctatagacag cattttcttc gataaactca cgacgaggct
     2281 ctactcgatc ccccatcaac atatcaaaga ttttatctgc ttctgcagca tcatctacag
     2341 aaactctagc catcaagcga tgttcgggat ccatggttgt ttcccacagc tgatgatcgt
     2401 ccatttcacc tagccccttg taacgctgaa tagtcggttt ggtacgacct tcactataac
     2461 gggctaaagc ttcttggagt ttgatttctt gatctgcacc cggctggata tattctttaa
     2521 tctcgcttcc aaccttgaca ccatagattg gtggttgggc aatataaaca taaccagctt
     2581 ctaggattgg tttcatataa cgataaatca aggttaaaag aagggtacga atgtgggctc
     2641 catcgacatc ggcatcggtc atcaaaacga gtttttggta acgggctttc gaaacatcaa
     2701 attctgcgcc aaatcctgtt cccatggctg tgaaaagact acgaatttct tcgttggcta
     2761 gaatcttatc catacttgct ttttcaacat tcaaaatctt accgcgaatt ggaagaatag
     2821 cctgaaactc acggttacga ccagatttgg ctgatccacc agctgagtct ccttcgacga
     2881 tgaagagttc tgtttcagca gggttattag aagaacagtc tgctagtttc cctggaaggt
     2941 tggaaatttc caaaccagat tttttacgtg tgacttcacg cgcacgcttg gcagccacac
     3001 gagccttggc agccaaaatt cctttttcta cgatacgttt ggcaatctgt ggattttcca
     3061 tgaggaaatc ggagaaggct tcactgaaga ggcgattggt aatcttgacc acttcgctat
     3121 ttcccaattt ggtcttggtt tgtccttcaa actgtggatt tgggtgttta actgagataa
     3181 ctgcagttaa gccttcgcga acatcttccc ctgttaaatt atcttcattg tctttcagta
     3241 acttattctt acgagcataa tcattgataa cacgagtcag tgccgtacgg aaaccttgtt
     3301 catgcgttcc accttcatgg gtatgaatat tattggcgaa actcatgaca ttttcatggt
     3361 aacctgttgt gtactgcatg gctacctcaa ctgtaatatc atccatctca ccgtctgtat
     3421 agattggtgt atcaaagatt acatccttgt tctcgttgat atattcaacg taactagcaa
     3481 tcccaccttc ataatgataa tgcttggttt gttccaaacc ttggcgctta tcagtgatag
     3541 aaatttgaag accgcgattt agaaaggcca actcttgaat ccgtttattt aatttatcaa
     3601 aatcaaaggt tgttgtttca gtaaagattt ttgggtccgg tatgaagtga accgttgttc
     3661 cagttctatc tgtatcccca accacctcaa ggtctgcaac aacatgacca cgacggtatt
     3721 cttggtaatg aatcttaccg tttttatgga catgaacgtc taattgagtg gaaagggcat
     3781 taactactga cgaccccacc ccgtgaagac cacctgaaac cttgtatcca ccaccgccga
     3841 actttcctcc agcatgaagg actgtaaaga cggtctcaac agcaggacgg cctgtttttt
     3901 cctgaatatc gactgggata ccacgcccat catccacaac agtaatcgaa tcatctggct
     3961 caataaaaac ttgaatatgg ctggcaaatc ctgccaaggc ctcgtcaatt gagttatcaa
     4021 caatttccca gactagatgg tgaagacctt cttttgaggt tgatccaatg tacatccctg
     4081 gacgcatacg aacagcctct aagccctcta aaacttgaat ttgactggca tcataatcct
     4141 gtgcctgcag atttttgatt tcttctgtca tcttattcct ttttcttata tgtctaatac
     4201 ttgtcttaaa ttcacgatac tggtaaacaa gtgggtatca agtcctgcag cttgacctgc
     4261 ttcgatatca atcggccgat caccaatgac aagaccagag ctaatctgat acttttctct
     4321 taaataaagc atggattcgg gatttggctt tctcttaaag cctgagctag aagtcaccac
     4381 ttctgtaaaa taagctgcta tagaggtttt ttctaaaatt tccaaaacct gatcatttcg
     4441 atgagagacc aaaaaatgac ggccaccttg atttaaaatg tcttccaata ggtcagaaac
     4501 tccttcaaat aaaatcgggt gttcaagctc tctggcttca ttttccttgt acttttctaa
     4561 aaaattctct aaattgggag cgaatgtctc aatcgcaaaa ggagtagaaa cctttaaagc
     4621 ttgatagaca ctgtcatggt cttgtgtgat accatacagt gccaatgttt caacaaatgc
     4681 agctgttgaa gtttcataat tatccagtaa agttccacct aaatcccaga tgtaatcgtg
     4741 atatttcata cccttcatta tagcattttt ttatgaaaaa agcgatgatt tccctgagtt
     4801 ttccacataa aaaacgagag aataactccc gttttactga tttttaccaa agacatctcg
     4861 atagagcatt cctgttcgta aactctctgc gtcccctcct agttgctcca ccaactcgta
     4921 ggcaaaggca agggctgttg aaggaccccg actggttgtc aactgaccat ctaccactac
     4981 tgtttccttg acgtagtgac catcaaggat ttgctcttga acgccgtcat aacaagtgta
     5041 tcgcttattt ttcaatatct ctgcttgatt gagggcaatt ggtgccgcac aaatggctgc
     5101 tagtttcttc ccttcttgct cgaagctttg caattcttga atcaaggtct gattatcacg
     5161 taaatgtgca gaaccaggca tacctccagg aagaacaatc atatcatagt ctgataaatc
     5221 tccatcaaag acatgatctg ctcttacttg gattgcatgc gaacccgtta cttgctcttc
     5281 aaaaccaacc atatcacatg tgatattggc tcgacgcaag acatctacaa ctgtcaaggc
     5341 ttcaatttct tcaaagccct gagctaacat aactgctact tttaccatga ttttctcctt
     5401 atttaatttg ttttaataca acctttttcc gtttgaatgg gacttttccg ctcttttctt
     5461 cagctagatt agtctggtaa ctcatcgata aaagcaaacc aacaccaatc agattactga
     5521 taatagctga tcccccttgc gaaatgaaag gcaagggaat ccccgtcaaa ggaagtagtc
     5581 cagtcacagc accgatattc tcaaagatgt ggaagagcaa catcataatc aaacctgtgg
     5641 aaatataagt gtagaactgg ttatttgatt taagagtaat cttcaacata cggtaaatca
     5701 acatgagata gagggcaata accaggacag agccaataaa gccaaaatct tctgcaataa
     5761 ccgtaaaaat catatctgac tctcgaactg ggataagcag attcgaagca ttaaatccct
     5821 gaccaaataa gccaccactc ccaatggcaa tctgcccttg agcctgctgg taagtcgttg
     5881 tttgggcaaa ctcaaaggga ttgagccaag ccaaaatccg attaatttgg taggtcggca
     5941 ttccaatctg gtgaagaaaa gctcgtccgt ccttgctaat aaagatagct aagaaaccag
     6001 caactcctgt tacagcagtc acaaatactg ggataataat tttccaagaa acccctgata
     6061 ataaaacgat tcctgagaaa atggctacaa aaaccaaagc cgtccccaag tcactttgaa
     6121 gtgctaaaag aactaggact ggaatggtaa agagaatcat ccagaaaatt aacaaaaagt
     6181 ccagcggaac cgtgcgtctc cattccttat gtttctttgt aaattggaca atgacacgag
     6241 ccaacatgag gatataggat atcttcataa attctgacgg ttggaatagg gtaattccat
     6301 ttattgatac ccagtttttg gcacccgttg atgcaactaa gcttggatta taaaatacaa
     6361 tcggcaagat cataagtccc aagcctaaaa tatatagaaa gggggtcacc ttccaaagaa
     6421 attctgtatt aaagagcatg accacaaaac caatcacaag ccccaaggca atccaggcga
     6481 cctgctgccc taaaatgggc agaatattat tgggataatc atgactaacg gctatataga
     6541 tagccaccac accgatgacc agtagaaaaa atactggcaa gagcaaactg taatcgactc
     6601 ttgagtcgag agaacgtttc atatatacta accttatact ttcatacaat actatttatc
     6661 aaagttcatt aaaaaatcta tcaatagcct cgtcaacttc ggatcgagag atggttttaa
     6721 cagtcgcttc ttctgctaga gatgctacta tttgtttgcc gtatcgtttt ccgacgattc
     6781 tcctatccaa aataagagtt aaggaacgtt ggtattcacg tctcatactt cttcccaaag
     6841 cctgttttaa acgaataatg gccattggta attgataatc ataaaaggca tttttccctt
     6901 cttgattcag ttcttgatta atctttttcg tcaagggttc ttgaggattt tggaaaggaa
     6961 gcctcggtac aacttgaatc acaaaaggat ggcttgaaaa atcaactccc tcccagaaac
     7021 ttgctgcacc aagcaagatt tgttgttcac ttttttcaaa gcgtttcttt agccgatgaa
     7081 catccccatt tttatactga gccaagtggc taactgtaag taaatccgat actgctagaa
     7141 gcatgtcttt agcggtaaag agaaccaaaa tcggttgctg gaaagcttga atttccacta
     7201 gtaaagcagc tacctctctg gcatagactt ctaaggaggt ttctgttacc agagggaaat
     7261 ctttgaccat gaccacttct tgttcctgtt ttccccgaga ttcaatcttg acaaatttgg
     7321 cttcaggata gcctaaaagg tctgccaaag aaaccctctg actaatctca agagtagccg
     7381 atactcccag gacttggcaa ctctcaggaa gtaaagagga cagaagagta cggcctgatt
     7441 ttgtagaaga aatctgaatt ttcttttgac tcgtttcagt tacttcaagc cagtaatcac
     7501 cttcagctgt aaaatagcga accagctcat caaagccttc cacttctaat tctgaaaaat
     7561 actgatggag attgtccaga gaatctaaga tatttttcct agatttgcca gactgaaatt
     7621 gttctatcaa gtagagacac tcaaagcgaa tactttctag tatccgttgt tgaaccctgt
     7681 tttcttctcc tactaaagcc ttatcaatta aatcgataat agattgtata tcgtaggtct
     7741 cttgaagcag attttctaga gctaacaaaa tcttttggac ttcatcaata atcagtaaac
     7801 ggtcactgac aaattcagga ttatcttcaa gtctggtcac gagataggca tgattagtca
     7861 ctaaaagctt gcaagtctct gccctttctt gactacgttt ccaaaaatct tccgtcacaa
     7921 ataagctctg ggatgataaa ttcccatcat gacgaaggtc tgctagaaaa tgttggtaac
     7981 ggtagagttg cccgatttca tccaaatctc ctgtctctgt ctcagtaagc cagaccaaga
     8041 cttgcatttt aaagcgtcta aataagcgat tttcatcatt ttcctgcaag gaatgataaa
     8101 aggcatccaa cttcagataa ttttgtggtc cctttaagct atgaatatct gtatggaaca
     8161 cttccttgag gcgtttacct tcttcttcca tgatttgatt ttgaagaatc tttgtcggaa
     8221 cactaagaac aatttgtcgc tctttggatt gagataaagc gggtaagaga tagccatagg
     8281 ttttcccaat ccctgtcggc gcttgaatca gagagacagg ttcatctttc aatagcaagc
     8341 caacctcttt agcaaaactt tcttgttcct ccctcacttc aaggttcaac agagaaatat
     8401 ttttagaaaa gtcttgagat agttttcgtg gctccagaga agctgccgtt ttcttaaaat
     8461 acagaccttg aacttggacc aagtctggag aactcaggat agattggttg cgataagttt
     8521 cctcaataac caggtaggac tcatatagga gagcgtcagc catttccagc aagcgttcca
     8581 agagaccttt aggaagctga gtcatctttt ccagtaaaaa aagaagtaat tctgctgtag
     8641 cttgggcatc tgaaagggct gtgtgtgcgt gtttaagagg aattcctaat tctcgacaca
     8701 aaatcggcaa gctatatttt tccagttcag ggaaaaagac ctgggccaat tcgaccgtat
     8761 caacacgagg gtttcttagc tcatagcctt caaaaaataa attttccgcc aagagattag
     8821 catcaaactg aacattatgg gctacaaaaa tcccatcctc caccaagtca aatatttttc
     8881 tggcaacttg cgaaaaatca ggtgcttgcg ccagacgttg gtctgtcaat cctgtcagtt
     8941 ctttgatatg agcatccaag ggttcatgtg gattgacatc cgtcgtatag tgatcgacga
     9001 tttctccgtc ctcaatcacg acaattccca cttggataat tttagcctta ctacctgtgc
     9061 tagttgcctc taaatccacc acaacatagc gattaccaat cgttttcatt ataaaaaatt
     9121 ataccaaaaa aagggccatt tggcacctgc aaacatagga taattttcaa actcaagaac
     9181 actacttttc ttaaaaatcc catcgaatag agcattctag cctgctgatt ttttaaaata
     9241 gtgaagaaat acgaaaaatt gagagaagaa atgttttcat cttccttctc tcaacgaatc
     9301 atgtatttta tttaaccatg tcaggatcgt agtcataaaa tcctgtatca aggaaacggt
     9361 ttttagggtg aagtttacga acttcttcat ccagcaagaa ggcttggtca tggctaaagt
     9421 tgccctcttg aatcaagcta cgcgcttgga taaagagttt tgcaatctca acaaagttct
     9481 gaccaggagt gtagagccct tctagtttcc agcgagtaaa gccatgctcc accaattctg
     9541 ttaatttgat catcaaatca aggtcattgt tggcaaagat atgggtccca tgattatctt
     9601 caaaaatgga atagtggctc tctggatcac ttggctcagc caagaagagg tcacgtttat
     9661 gcgtcttttc atcatcgata tgtgtaaagt tatagtagtt ttgtaagagt ggacgtttag
     9721 aatgatggat gacgctagca ccgtaaacca aaacttcagc aggaatttcc aaaatctctg
     9781 gcattttgaa aagttcagct gatggaattt cacgcgccaa aacagcctca gatgcgccag
     9841 ccttttgtcc ccagaagtta atctgacgac tgctagttac catggttgaa gcatcgtaga
     9901 tggtcttaaa tgaataacta tcgcggttaa ctacgtaaaa gacgcctgca tccccaatcg
     9961 taatatagtc tgtcttgatt tcttccaaga agtctaagaa aggcttgata cggtccatca
    10021 tatcttggtg catgagagca ttgaccgcaa cgatcaattc cttaccagca tcatgaacca
    10081 acttagcgat ttcacgtaat tggtcataac taaaggtcgt tggcagacga aggccaaaat
    10141 ctttctcacc gacatagata cggtctacgc cagcttcgag tagttgttca acttgttcaa
    10201 tactttcagc agttgctgta atgacaatct tttccataag aaaaattata ccacatttct
    10261 ccaaaatcat ccatgctttg aaaatgaaaa gggactttat tctttttgta acctttctgt
    10321 aataattctc tgccgaaaaa atgataaaat aggtatgtac tgttaaggag agaattatgc
    10381 ccgtaagaaa attacaatcc tatgaggtag actatcaaga agaattaaac cagcagcttc
    10441 ctcattacca agcttataca cctgaagcgc aatctgatgc caatctcaag gaaatcctat
    10501 tttttattaa tatcgctgtt ttttgtatct gtattgctat ctttagtttt atctttttag
    10561 cattaaaatt atcaactgct cttgcctttg ccgcagcaat cggattcagc ttacttgttt
    10621 taaaagttca acggtctatt atcaaacgaa aacgtagaag ataaatccaa aatatcgccc
    10681 cagttggagc gatattttta ttttttcttt ttagatggtg tctgaatggc aatcttcact
    10741 tcaaagattg ttcccttggg tttattatct ttgacagtaa cagttccttt tagagcatct
    10801 acaatttgct tggctaggga taatcctaaa ccaaaaccac ctttttgccg agttctagcc
    10861 ttgtctactc gataaaaacg gtcaaaaatt ttctttttat cttctgtcga aataccgatt
    10921 ccattatcag aaacaagtaa ataaagattg cgatcggtcg ccgagataag aaaatcaatt
    10981 tcaccatcct cctcagtata cttgacggca ttatcgaaaa gaatggtcat cagttgtttc
    11041 agaagaagct gatctgtgac aattgttcga tggatacgat tttcaaaacg gaagacacga
    11101 ttattttccg aagcaatcat ctcgtagttt gtgaaagttg tattaaaaaa gctagttgga
    11161 acttctgcaa gctccggctt aatcccatca tctctccgag ctaagttcag caagcttgtc
    11221 gttaaaaaac gcatatttcg gacttcttcc aaactcgatg caatgctttc gctcacatcc
    11281 ataatggtag cttctggctt acgaaaaagg gtctctaagc gattttgcaa aactgcgagt
    11341 ggagttcgta actcatgact ggcattttcc acaaaagact gttgcttctg catactctca
    11401 agcaggggcc taacactgac cctagctaga tagaggctgg caagtaaaga caaaatccag
    11461 aaactagcca tcacgaccac aatcaattgc tcatgctttt gactagcctg ctccaactga
    11521 ctggtattaa tcaagacagc agcatacttg atattggttg aaaccgaact aatattggtc
    11581 tccatcaaaa tcacacgata gatttcttcc tgcccatagc tattaaaaac ctgaatctgg
    11641 tagatatgtc ctagttcttt cttttctaac ttaatcttat ccaagcccaa aaatcgattt
    11701 ccagaaagaa gttgagtaaa gtccttatca aagagaataa cttccgtatt ggaactgaca
    11761 ttaggtttta tttctacttt actagcgtcc gccctagcat tttctaaatc tttaatctct
    11821 tctgttgccc tatttatagc cagctgaata actgcttgag gattttcact cagtccatga
    11881 agcttatcgt ccaccgaagt ataaagactc gaatgcatga cttgtaaaat aatcagagtc
    11941 attgtagaaa aaatcagggt gaagacaccg aagttgcgga taaaataact aaagtcatcc
    12001 gcataccatg tttttttaag tttactgaac atcttttaaa agatacccaa cactacgcaa
    12061 ggtttgcaaa ttctctgcaa aagtggttcc ctttaatttc ttacggactt ttgaaacata
    12121 gacttcgaca accgaaatcg ttgtatcact atcaaatccc catagacggt caaaaatctg
    12181 cgtcttaggc aaaatcacat tttgattttg aaggaaataa actagtaaat cgaactcttt
    12241 ccccagcaat tcgacaggag tatcttcaac tttaacggta ttggttgata aattaaccac
    12301 gatattccca taagtcaagg tgttttcatt aaacttccct gaacgtttga gaagggcctg
    12361 aatccgcatt ttaagttctt ctaggtagaa aggtttggtc agataatcat ccgctcccag
    12421 ttcaaatcca tgtcccttgt catccaaact ttccttggca gtcataatca gaactggtgt
    12481 cgtaattccc ttttcacgca attcttttaa gacttggaaa ccattttttt ctggcaacat
    12541 caaatccagc aaaatcaaat catagacacc actctcagct tcgtagagac cttcttctcc
    12601 atcaaatacc tgcataacat ccgcaaaatc gtctaaaaag tcaaatactg aatttgacag
    12661 acctaggtca tcctcaacca ataagatttt tatcatgaga aactcctcct tattaaaact
    12721 attataccaa atttgcctta aaaaaaactc aactctctgc attttacatg agatagctga
    12781 gttttctttt tattttaggc ttatttatgc atttccgtat tgaagaacaa ctgcttcgac
    12841 tgcagctttt tcacggctaa tcaagtcaac acgtgctgca atttccttga ttcccatacc
    12901 gatgttacgg ctaagagcaa ggtcagaaag ttgcggctca aagaactcct tgtattccgc
    12961 caagcgttgc tgagtcttaa atacatgagc aggaaggata acaaagctat caaagctcat
    13021 atctcctcca agggctgcct taatccaagc ccagttttca cgcgcccaag accaagctgt
    13081 tttctgagtt gcttgatgag ctaggaattg ataataccaa gcagacaagt cctgtggttt
    13141 gaccacaaat ttgtccttcc aagaagtaat caagttttgg atattatccg catctgtact
    13201 gtatgcaaga gctgctgcca actggcgttt aaagacagca tctgttgcgt gagtataagt
    13261 atcaagataa agtgctaaca agtctttagt ctcatgatgt ttcatctcat taatcagaac
    13321 ttgtgaacga atagctgctg ggagtcctgc aagattctcc ttgtgtgttg cgaagatttg
    13381 gctagcgact tgactagctt ctgcatcatt tgagcgaatc atcatcgaaa cagccagctg
    13441 acgaaccaat tcatcctcat ctgattctcc gtctttagct tcaaaaccaa gacggtcata
    13501 gttatgacga gccaatttag caaccagtcc tttgaaggct gtttcagcat ccgttccttc
    13561 atcaataaag cgctcaaggg ctgaaatcac ttgagaaaca gctgaaacca ccagataaga
    13621 ctcttcctta gcaagtttat caagaactgg aagcaagtct gcataagaaa tgtgccctgc
    13681 ctcagccaac aaacgacgtt cttgaacaat ttgcagtttg cttgtgttat caagtgtctc
    13741 tagctcagca agaacagctt ctaacaagtc tccttgatag tcggtaatat agtgggcagt
    13801 attttcagtg ttgagacgaa gagctccttc attttcagca agaagagctg cgtagccagg
    13861 gatttcgata ctttcagttt cgagtgtatc aggcaagcct ttccagttgc tattgagtgg
    13921 caccacccag agacggttct tgtcttcgtt ctcaccgatg aagaattgtt tttgtgaaat
    13981 cttcaagaca tcattttcaa ctttgacagt aagaactggg taaccaggct gttccaacca
    14041 agaatccatg aaggctgcga catcacgtcc tgacgcttga ccaagggcat cccaaaggtc
    14101 actaccaatg gtgttgctgt attggtgttt ttcaaagtag gcgtgcaaac ctttagcaaa
    14161 atcagcatct cctagccaac ggcgaagcat gtgcatgaga cggcttcctt tggcatagac
    14221 gatagcgccg tcaaagagtg tattgatttc atctggatgt ttaacttcga cgtggacaga
    14281 ctgaacgcca tcagtagcgt cacgttcaag agcaagaggt actccacctg tttggaaatc
    14341 ttcaaagata ttccagcttg gttcgatggt atccacacag acgtattcca tcatattagc
    14401 gaaactttca ttgagccaaa ggtcatccca ccatttcata gtcacgaggt tcccaaacca
    14461 ttggtgagcc aattcatggg ccacaacaag ggcaacttgt tgacggctag caaatgtaga
    14521 gttctcatcg acaaccaagt aaacttcacg gtaggtcaca agaccccagt tttccatagc
    14581 accagctgag aagtcaggaa gggcgatgtg gagagattga ggaattgggt acttaactcc
    14641 atagtaatct tcgtaaaact cgatagagcg aacagcgata tccagtgaga aatcaagatt
    14701 tgaaagtgga tgtgctttgg ttgagtagac acctaccagg gtaccatttt tagttttagc
    14761 ggtcacccct tgcaaatcac cagcaacaaa ggccaacaag taagaagaca tgcgaggtgt
    14821 tgtctcaaac ttccagatac ctgtttcctt acggttttca acatcgattt ctggcatgtt
    14881 tgacaaggcc aattcacctt ctgcttggtc aaagcaaaga gagaggtcaa aagttgcttt
    14941 ggcttcaggc tcatccacac atgggaaagc ttcgcgcgca aaatggctct caaactgagt
    15001 agacaagacc tccttcttga ctccatcaac tgtataataa gaagggtaaa tccctgtcat
    15061 gttgtctgta attttaccag aaaaggcaag aaccaattca acttgaccag cctcagccaa
    15121 ttcgatatga agggcttcat tgtcatggtc aactgtaaat ggacgagctt gacctgcaac
    15181 ttctacagag gtgatttcca agtctttttg gtggagggag atgcggtcac tctgtgcttg
    15241 accagtgatg gtcactttcc cagaaaaagt cttggtctca cgactcaaat ctaaaaataa
    15301 atcataatgt tcaggaacaa attgcttaat aaaatgttca actgcttgca tagttttctc
    15361 ctattctaag tttaagagct gctgctcttc ttcaaacaaa cttattatat catattttgc
    15421 ttgagaaaaa aggattggac agcgatttcc aaaactttct tccttctaat agtctacagt
    15481 gggtagacct tgcgaaattc ttctaaaaca accttgcttt caggtgtaaa agtcaatcct
    15541 gcttcaccca agcagtctct gaaaaaatcc tcatgaacct ggcgccaata gacaagtgtc
    15601 ttgtttccct caccttcctt ataggcatgg tcagctgaca ctcgattgaa gggtttaaca
    15661 gaaacctttg taatttcgac aatgcagaca gcctgatttt gactatctaa aatgacatcg
    15721 aaggtcccta cttggggaag tggttcgtct tctagtacat agaggtcata ggctgatgct
    15781 gttgctgtct tttctccttt aaacaccaaa tccgctaaaa ggtctggttc aactccaaaa
    15841 gcccaggcat cgatttcatc tccgatagaa ggattgattt gtttgtattt attccacatt
    15901 tcttgcggtg tcatgggtgc tcctttgtaa ttttttactt tcttctttta tgtgtttaag
    15961 atgatctgga tggtcaatct ctaaatcaaa aatctctgga atagaactgt agtggataat
    16021 gcacttgata cccaactgat tcattttttg tatgaaagaa gtattcagat agcctgctac
    16081 agcaaaatca atcttgttct ttcttgcttt atcctacata tctcttagca tatctaacat
    16141 tattggactt tccatatcat gccattgact gtttctcata gtcacaaaaa caaaggaagt
    16201 caaatcattt attccaacta caatctttga aatgcccgtt tccagtatcc tatccaagtc
    16261 aaaatacgct gacggtaatt caatcatcgt tccgactttc ccagtaaagc catactgacg
    16321 caatactgta atagcttgtt ttaattggtc ggcatcattg acaaaaggaa aaataagaga
    16381 cagattagga ttggtttgat aaacttctgt aacgacatgt acttcagcct gaaattcatc
    16441 caaacacgcc agtaaacgcc tggttcctct atagccaaac agaggataaa ttttttcaag
    16501 aattttttcg ccactaaggg caagttgatt tttcatcatt caccttccaa ttcatgtaag
    16561 aagtcttgtc cagttctgga aatcctaata attcagactt aaccttcaag actaatggcg
    16621 atgcattttc ttctgtaatc tcttgaatat ccatccaaat atatccaagt gaatcattcg
    16681 caccatcaga cacagcttcc gaagtcgtaa cttgaggtgc actctcattc atttcaacat
    16741 catacaaggc catgacatgg tgaaccataa aatttgttaa ctcttctctg acgaaaacat
    16801 cgtagattcg aggattagag tagcttctaa cagtaaatcc cgtctcttcc ataacttctc
    16861 tagtcagcgt ttccgtcagt ccttcaccaa gttgctgact gcctccaggt agatcatacc
    16921 gatgttgata agggcctctc gttttttcaa tgcagagtaa cttcccattt tctaagcaaa
    16981 cagcgtagac tccaaagtgt tttttgattt ccatccaact cctcctactt caaagaccag
    17041 ccaccatcta ttgtcaagat ttgtccttgc atggcgctcg cttttccact tgctaaaaaa
    17101 agactaagct ctgctatttc ctctggctca atccagcgct tgattggagt ttcactagcc
    17161 acccagtcag ccaaaccacc tggttcaaaa tccgcagcgg tcatagctgt cttgactgct
    17221 cctggagcga taccaaagac ctgaatccca gcttcagcat agtctagagc caactgcttg
    17281 gtgaagccag ccaaggcatg cttggatgaa gtataggcgt gaccacctcc acctgctagg
    17341 ctagaagcaa tggaacacat attgatgatg attccctttt tattttccag catttgtgtc
    17401 aaataatacc gagtcaactc tactggaata atgtagttga tttcaaaaat ctcttgaatg
    17461 tcctgcgccg tttgttccaa cagtggtttg taatcatcca aaactccagc agtattacac
    17521 aaaacatcca cctgagggca ccagtcaaaa ataggttcca agtccaaggt caaatctctc
    17581 tgtaaaaagt gaaaatcacc ctctaagagt ggcttttcac cttggtcaac tccataaact
    17641 tgatagccct tctctaaaaa gaggcgagct tgagccaatc cgatccctga actcactcct
    17701 gtaatgagta cacgtttagt catgcacttc tacccaatcc gttgccaaaa catcacaagc
    17761 tgtcgggctc cacatggaaa aaccttctcc ttctccagac acgttgatta ggaaataagg
    17821 tgtcacttca agtgcaagcc cattttgctc gatggtatca aagagttgga catagttttc
    17881 agcacctccc caaccagttc gtacatattt tttcttagcc tttaagccag gtagaatttc
    17941 ttcaaatgtc atgtttttct cctttaatgt caataattct ccccttcatt ataacaaaaa
    18001 aaccgcttta aaacggcttt ttgactgtga tttatttaca tcttcttcta cttacggcaa
    18061 attattccct gcagcaagat aaatttcata ccattctttt cttgttaagc taaagtttgc
    18121 cgcttggcta acttctctca agtgcttagg atttgtggta cctacaactg cctgcatttt
    18181 tgctggataa cgcaatatcc aagaaatggc aatagttgaa gaggttactc catatttaat
    18241 agctaaacga tcaagtactt gatttaaagc ttgaaatttc tcatttccaa caaaattccc
    18301 tttaaaatac ccgaattgta agacagacca tgcttgaatg accacatcgt gtaattggca
    18361 atattcaaaa atgctgccat ctcgcatagc tgcttgacta tcttccatat taacatgaaa
    18421 agctgattca aatcctggag taaaagccgc actcaattgt agctgattaa cagctaacgg
    18481 ctgcttgaca tcttttttaa gcaactccat catcatagga ttttgattag aaactccaaa
    18541 atctcgaact ttaccttgtt tataaaggag attaaaggct tctgctactt ggtcagattc
    18601 catcaaagca tctggtcgat gaaggagcaa gctatctaga tgatcaatct tcaatctttg
    18661 caaaataccg tctactgatt ttataatata gtccttagaa aaatcaaaat aggtaaattc
    18721 ttcaatgcga atgccacatt tggactgaat ccacatcttt tctcttaaat ctggacgatt
    18781 ttttaggaca agacctaaca gttcttcaca acgaccacga ccataaatat cagccaagtc
    18841 gaaggcattg attccaacag aaagtgctgt ttctacaagc tcttcaactt cttttacaga
    18901 cttatctttt attctcatca ttccgagaac aatttctgat aattctttgt catcttgacc
    18961 aagagttatg tatctcatca aatttttctc ctttaatttc taacattctt cccttcatta
    19021 taacaaaaaa ccgctttgca acggcttttt gactatactt cactccattt tatcttctta
    19081 aacccacgga acaagacaaa gattccaata aagaggacag ctaaaggaat aacttttgta
    19141 aggaaaacat ttgaaattcc catccactca taataacgga gcagagaacc caccacaaga
    19201 tgggcaataa tcatactgac aaatggacga aagaccgctt ctttccaatt ccaaataccg
    19261 ataactagcg aaatcgtaaa gatagacaaa ctatcccagg gagccggaat ataaaaggct
    19321 ccttcttgta tgaagcttgc cattcctaca tatcctaaaa caactagaag aactatagtc
    19381 ccaacaacaa tgtaagtgcc aattttcatt ttaggagaat cttggactaa acttcttcgt
    19441 aaaattgtgg ccacaagtcc aaatccaatc agaaaaataa gaagttgccc taaaaatgtg
    19501 agcaaattga ctgttaagag aggaccttta gaaaaatcac ttagtagttg ataataacgt
    19561 aataccgcca ggacaagaat tggcgtcaaa agggactctt tgatagaact gcgaggtgct
    19621 cccttgagaa tctctttcat tattttttta ggattcttac ctagataatc ctctgcactc
    19681 atgccatctc gttctgcttc tgagaaatct agcatcatca aatagatctg ctctctgaga
    19741 tagtcttcat catagagaaa tccagcaaga ttaaaacttt cccacaactc ctcaaaatac
    19801 ttttgattct cctcagaaaa ctcatgtagc aaagcgcttg tttcttcgta atacttcatt
    19861 ttcttcatgg tttaaccccc attcttaatc ccttctactt tttgactcaa atcgtcccat
    19921 tgttgccaaa agactgagac acgctcttct ccttctttca ttaatgaaaa atacttccga
    19981 tctggaccat ctggcgacgg gcgcatgtcg cctcttatcc attgattttt ttctaacttt
    20041 tgcaacaaag gataaatagt tcctggaacg atagtatcaa atccagcctc tcgcaaagtc
    20101 tgaaccaact cataaccata ccgctctttt tgaccaatca tatccaagac acaaccttca
    20161 agaacacctt ttaatagctg agtttctttc atcacttctc ccttctaatc tattttgtaa
    20221 tacctactag taacttcacc tatagtatat tacttctaca ctagtttgta aagcataata
    20281 gttaatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgccctaccg tatgtatggt
    20341 t
//
LOCUS       DAVMAH010000039        20242 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVMAH010000039 DAVMAH010000000
VERSION     DAVMAH010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20242
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.039"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(137..286)
                     /locus_tag="VYO94_001418"
                     /pseudo
     CDS             complement(137..286)
                     /locus_tag="VYO94_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(440..2071)
                     /gene="rlmD"
                     /locus_tag="VYO94_001419"
     CDS             complement(440..2071)
                     /gene="rlmD"
                     /locus_tag="VYO94_001419"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1760049.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVATRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2145..3119)
                     /locus_tag="VYO94_001420"
     CDS             complement(2145..3119)
                     /locus_tag="VYO94_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV1760050.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3193..3807)
                     /gene="pmp23"
                     /locus_tag="VYO94_001421"
     CDS             complement(3193..3807)
                     /gene="pmp23"
                     /locus_tag="VYO94_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV1760051.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTDNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3807..4781)
                     /locus_tag="VYO94_001422"
     CDS             complement(3807..4781)
                     /locus_tag="VYO94_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV1760052.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4789..6045)
                     /locus_tag="VYO94_001423"
     CDS             complement(4789..6045)
                     /locus_tag="VYO94_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV1760053.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQAPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6107..6538)
                     /locus_tag="VYO94_001424"
     CDS             complement(6107..6538)
                     /locus_tag="VYO94_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760054.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSLEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGEGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6540..7142)
                     /locus_tag="VYO94_001425"
     CDS             complement(6540..7142)
                     /locus_tag="VYO94_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV1760055.1"
                     /translation="MIDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7126..7965)
                     /gene="prmC"
                     /locus_tag="VYO94_001426"
     CDS             complement(7126..7965)
                     /gene="prmC"
                     /locus_tag="VYO94_001426"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV1760056.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASNQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     RQD"
     gene            complement(7965..9044)
                     /gene="prfA"
                     /locus_tag="VYO94_001427"
     CDS             complement(7965..9044)
                     /gene="prfA"
                     /locus_tag="VYO94_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV1760057.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9041..9631)
                     /locus_tag="VYO94_001428"
     CDS             complement(9041..9631)
                     /locus_tag="VYO94_001428"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV1760058.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            9754..9936
                     /locus_tag="VYO94_001429"
     CDS             9754..9936
                     /locus_tag="VYO94_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV1760059.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10072..11445
                     /gene="mnmE"
                     /locus_tag="VYO94_001430"
     CDS             10072..11445
                     /gene="mnmE"
                     /locus_tag="VYO94_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV1760060.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTESFAIAQKIFKGKDL
                     SQVASHTLNYGHIVDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSILNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11492..12427)
                     /gene="dapA"
                     /locus_tag="VYO94_001431"
     CDS             complement(11492..12427)
                     /gene="dapA"
                     /locus_tag="VYO94_001431"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV1760061.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12483..13559)
                     /locus_tag="VYO94_001432"
     CDS             complement(12483..13559)
                     /locus_tag="VYO94_001432"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV1760062.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(13901..13973)
                     /locus_tag="VYO94_001433"
     tRNA            complement(13901..13973)
                     /locus_tag="VYO94_001433"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13938..13940),aa:Thr,seq:ggt)
     gene            complement(14073..14582)
                     /locus_tag="VYO94_001434"
     CDS             complement(14073..14582)
                     /locus_tag="VYO94_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV1760063.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(14580..14676)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            14705..15136
                     /locus_tag="VYO94_001435"
     CDS             14705..15136
                     /locus_tag="VYO94_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV1760064.1"
                     /translation="MKKPIQKFFNNEILAYLFFGIVTTLVAILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLLFTFLFVTQFP
                     HIIGQFVNENIDKINAIETIIAQILIIIINYILSKIYIFRK"
     gene            15218..15595
                     /gene="mscL"
                     /locus_tag="VYO94_001436"
     CDS             15218..15595
                     /gene="mscL"
                     /locus_tag="VYO94_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV1760065.1"
                     /translation="MLKDLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(15637..16731)
                     /gene="hemH"
                     /locus_tag="VYO94_001437"
     CDS             complement(15637..16731)
                     /gene="hemH"
                     /locus_tag="VYO94_001437"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV1760066.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            16886..18109
                     /gene="pepT"
                     /locus_tag="VYO94_001438"
     CDS             16886..18109
                     /gene="pepT"
                     /locus_tag="VYO94_001438"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV1760067.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKTVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18145..18774)
                     /locus_tag="VYO94_001439"
     CDS             complement(18145..18774)
                     /locus_tag="VYO94_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760068.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTTGNQEKPVE"
     gene            18739..18960
                     /locus_tag="VYO94_001440"
     CDS             18739..18960
                     /locus_tag="VYO94_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760069.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19037..19579)
                     /locus_tag="VYO94_001441"
                     /pseudo
     CDS             complement(19037..19579)
                     /locus_tag="VYO94_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521835.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(19680..20222)
                     /locus_tag="VYO94_001442"
                     /pseudo
     CDS             complement(19680..20222)
                     /locus_tag="VYO94_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037046.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         5836 a         4246 c         3833 g         6327 t
ORIGIN      
        1 aatatccatt attaaaatgg atactataaa cagcacacca actatttatt ttttgagttt
       61 taaactttgg tagaagtctt gaactcctta tatttacata actatttgcc tctataacta
      121 ttatgacacg aaaccaacaa gcaagttcaa gcacctccat atctttattc aaatgaggac
      181 taagatattc acaaacttta tcataaacct ctttatcttt tttcataaaa ggggcataca
      241 acttagcaaa tttatcctaa aattttttgt tgcctttatc aatcatttca acactccttt
      301 aaatataaaa atgatcctat caatctttat attgagccta ttttctaatt gataccttgc
      361 aagaaaggaa taatagctgt tcctatacca agtaggaatg taataaatgc agaaagtcat
      421 atactgtcat tcttttctat taaatcattt tgaagtgtct caaagcatcc atgatggctt
      481 cttctttttc aggtgtacac tgtggaataa tttgtttatc ctttttagac ttgttgtaat
      541 gttctcgtaa ttctattcca catttctttt ttatctgtgc aatatataat gtcgaaactt
      601 ttaattcaaa tttattccaa acatattctt tgatttgagc atatgttgct ttgctctccg
      661 cacttgtcaa attcatctca tccagctcaa tttcaacact tatgtgctta tcgacatcga
      721 gtttggacaa aagtgctacc gtctcgacgt gatgcgtttg aggaaataga tccaccggct
      781 ggactttctt caattcatat cccaattctt ggtagagttt gatatcacgc gccatggttg
      841 cgacattgca ggagatatag gcgatgcgat cggctcctgt ttgggcgctt gctttgataa
      901 agctttctgt caagcccttg cgtggaggat caaccaagat aacggttggt tgaatcccat
      961 ctttaagcca attcttcata gcattttcag ctgtgtcaca gacatagtgg gcgtttgaaa
     1021 tattgttcaa ctgagcattt tttttactat tctcaaccgc ttctggaatc agttcaacac
     1081 cgtagacttc tttgacatgc ttggcgactg ataaaccaat ggttccaata ccagaataag
     1141 catcaataac cacgtcatct ttttttaact ctgcaaagtc aatggctgtt tgatagagtt
     1201 tctccgccat ttcagtattg acttggtaaa aggctgggcc agcgatttgg aagtcatttc
     1261 ccaacatctg gtccgtaata tagtcttgac cataaagagt gcgccactcc ttaccaaaaa
     1321 tcgcattggt attctggtcg ttgatatttt gcatgacaga cacaatctct gggaactgct
     1381 tgataacttg ttcaatcaat tggtcaacac gaaaaacttt tggacgagtt gccaccaaaa
     1441 cgaccatgat ttgtcctgaa tagtgaccac gacgcaccac aagattccga atcaatccag
     1501 actgttcctt ttcgtcataa ggttttaaat caaaacgacg gagcaggtct cgaagagcta
     1561 ctacgacttg gtcaatgaca ggatcctgga taaagaaatc ttcaaggggc atgaggttgt
     1621 gcgaattctt acggaaaaat cctgtttcca agacaccatt cactcgacga acgggcacct
     1681 gcgccttatt gcgatacttg actggatgtt ccataccaag cgtttcagca acttctacat
     1741 ctgcaattcc agcaatcttg tagagactgt ccttgacttg cttggtttta aacttgagct
     1801 gttctggata agaaaggtgt cctaaatccg cgattcctga acgcaggtaa gccaaatcta
     1861 gatcttgatt acggtgtggt gactggacaa ggtatttttc aacttttcca aagccaatct
     1921 ttttattgac cttgaggaca cgcatgagaa ttttttcact cggtaaagca ttctctacaa
     1981 aaaagaccaa accatctacc ttggcaactc ctgccccttc atgggtcaaa tcaacaattt
     2041 caacttctac aatatcattt ttctttaaca ttcttttctc tttctattgg ccgacaaaaa
     2101 agacggcaac gttacggtta ccatccatta taccatgaaa tttcttaaga accaaaactc
     2161 ttgaagaagt tgacaagggc ttgccagagg gagcttaaga agttaccacc gtcctctagc
     2221 gccttatccg catcaaagtt aaggttgata tttttaaaac tgtcgccagc ttgtgatacg
     2281 atgctttgtt taaggtcatt tagggtttta gtgaaatctg cattgctgag gatatcactc
     2341 tttgagagat tcaaggcaaa attgatgatg atattgatct ggtttcctgt tatgacctga
     2401 tcaagtttgt aattttttaa ggtatcttca acaatcttgc ggatatcttc ttctgtcaga
     2461 tttcccttgc tttctttagc tttggcgagt cctgacttga tatcagctag ggcaacgttt
     2521 aatttattag catcatagcc tgatttgtcc ttgttttcag cattgatatc tgacaaagcc
     2581 tttagctctt cttgagccaa atctttattg gcttgcggca ccttggctcc attagcttct
     2641 agcgaatagt agatcccagc caaagcactc tcacctgtaa ctggaatggg tgctgctacg
     2701 gtgattttgg cgtgttccac acccaaagtt acggctgcat ttcggtacat atcctgagtt
     2761 accttagtga tgttttcagg tgtttcaatc ttgacctcaa gtggcgattt gtcacctagc
     2821 ttttgaatct tggctgatga atacaactgt aagctagagt cattggccac attcatgatt
     2881 ttagaataaa catcaggtgt catggtcttg agttctttgg tatctgttga ggcattgtag
     2941 cccagttttt taagagtttg atttttttgg tcttcagata gggaagaacc taggacatat
     3001 tcaggttgga cataggtttc atcgataact ttttgaacat ctgttgctgc atggacgcta
     3061 ttcatagctg ttactgccca caagatcgca gcgctagtca gaaagagttt ctttctcata
     3121 gggaatttcc tcctttactt ctttagagta atatatctat cttaaagaaa acttataaca
     3181 aaaacacctg gtctagccag atgttgaaaa gagagtgaaa catttgatga tgtaaaggtt
     3241 aagtcgtacc tgtctagaat aataatagtt tcctccattt acatagagtt cagcaccgtg
     3301 aaaaatggaa atggggtgaa tataactata agtctttcca gtcgtattac caagcaaggg
     3361 ggcaacagtc tcacgagagt actgtttggc tagagccaag gtattttcct tgccattttg
     3421 ggcgataaaa tcgatatagg caggtccaaa attataggct tgaacagctg tccagatatc
     3481 tacacccttc ttctgcgcca gatagagatt gtctgtcaga gtttgaatgc cttgccgaat
     3541 gctagaggca ttatcattga tggtgttggt ggaaccactt gcagactcac tagactgcat
     3601 aacatcgcct tcttttcctt ttgtttcagt ataaatcata gcaagcacaa gctcttcgtt
     3661 tgctggggtg tctttttcac tcaagatttc tcgcaccatg ggttgatagg tcatgacttg
     3721 tttgacatct tgatgaacgc ggtaagcttt atagccagca aaaaggaaga ctgctagtac
     3781 aagcactctt cgaattcgtt taaacattat ttactttgga tatcctcgat atttttgatt
     3841 aagatagagt aggttccatt ttcgttttgg ataaactcaa cagactcggc gtcttgatag
     3901 acgttattgg gaacgatgag ctcaattcca tttgataagg agagtttttg gttttcaaat
     3961 ttctttaatt ggcgactggc atcaatttca tcaaattgaa caggttctgg tacggcttct
     4021 ttgacttggt caataaagct caaacgagcc gtcagattat tgtcaaaaag gtcattagcc
     4081 aatttctcag gtgacaattc attgctttct tctaggttgt tgaaaatcgc tgatttgacc
     4141 ttggattgaa attgaaaatc atctgtgtta aaagattcag caattctctg ggctgttttt
     4201 tccagttcct tgatagattt tttaggagaa atcttaggag cgacagcaag aagattatct
     4261 gaaaaatagt tcaaaaaagt cccgttgtac ttgattcgtt tttcaatcag gtgatacttg
     4321 cgactctgaa gattgaccac caaggcctcg tcagcacccg ttccaaatcc aggcaggtta
     4381 ttctgagtca gcttgattgg attatcaact tctcctccga ggtgggtcaa ggtctcccgc
     4441 agggcaattc gcaagaaagc gaaatgttct acaccttctt tagaaaattg aacaaaaatc
     4501 aagtcattgg tcttgagatt ttcagaaatg ctaaactcct ctttccagag attagccagc
     4561 gttactgatg tctccaacaa atcgtctgta atatgattga agaagggatt ttcttcttcg
     4621 aaaatcccag tcttggcttc atctgaatac acatgttcaa tttttttacg taggtattct
     4681 tcgatttttg gagtaatatt gagaaactta tctgctaaga acagctcggt atcatccgga
     4741 ctgaactggt gaataatggc tttcttaata taaatgtcca taaaagtttt attcctcgta
     4801 taatgggaag gcatctgtca attctttgac tgcacttctc acttcttcta atacagcctc
     4861 attttctgaa ttcttaaggg ttttaatgat gagttcagcc actttgcgac tttcttcttc
     4921 accaaatcca cgtgcagtaa tagctgctgc tccgatacga atcccacttg tcttgaatgg
     4981 tgacaaggtt tcgtaaggga ttgaattttt atttagggta atattgactt catccagcaa
     5041 gttttgagca acttttccgt tttctacaac cttagtcaca tcaacaagga agagatggtt
     5101 ttcagttcca cctgaaataa tacggaaatc aggggcttgc aagaagacat ctgccatagc
     5161 cttgctgttc ttaattacat tggcagcata ttccttgaag gctggatcca aaacttcttt
     5221 gaaggaaact gccttagccg ccacaacatg ctctaaagga ccgccctgaa tacctgggaa
     5281 aatagctgaa ttgatttttt tagcaagttc ttcgtcattg gtcaaaatca aaccaccacg
     5341 aggtccacga agggttttgt gggtcgttgt tgttgtgata tgagcgtatg gaactgggct
     5401 tggatgaagg ccagccgcaa ccaaaccagc gatatgggcc atgtccacca tgagcttcgc
     5461 accgacagca tctgcgattt cacggaattt tgaaaaatcg ataatttgag aatatgctga
     5521 agcaccagct acaatcagtt ttggttttac ttcttgggct tgtttcaaga tagcatcaaa
     5581 gtctaagagt tccgtttcag gatcaacact ataagaaaca aagttgtagg tttgaccaga
     5641 gaagctaaca ggagccccat gagtcaaatg accacctgat gccaaatcca ttcccataac
     5701 cgtatcacct ggctcaatca aggacatgta agccgcacag ttagcttggc ttcctgaatg
     5761 tggttggaca ttggcaaatt tagcaccgaa aatttctttt gcgcgttcaa tagcaagagt
     5821 ctctacaacg tctactacat cagttccacc ataataacgg cgtcctgggt aaccctcggc
     5881 atatttattt gtcaagatag acccttgagc tgccataaca gccttggaaa ctacgttttc
     5941 cgaagcaatt aactcgatat tattttgttg gcgttcttct tctttggcaa tagcattcca
     6001 gagatcagca tcatatgctt taaaatcatc tttgtcaaaa atcataggtc ttctccttta
     6061 ttgtgtgact agtccattag tttgatttta caataagaaa atcaaactaa aagatgcgaa
     6121 taaaccgttt ctgcatttta tcacaagtat agccaacttt ttcataaaat gcatgagcac
     6181 ccagacgatg attggcagaa tttaagcgga taaacccata accacatctt ttggcttctt
     6241 gttccaaccc ttgtagtaaa cttttaccga taccttcacc ttgcgcttga ggtgaaactg
     6301 ctaaagctaa gatattaaat cctgctttgg aatagagtga ttcgtaaact tcagcgtgga
     6361 catatccaag taagacatga ttagctgcat cctcatagcc aagtaggaaa tgatgggaat
     6421 cctgagacag tctagctagt tggctagccg tttcctctag actaaaagta taacccaaag
     6481 cctcttggtt gatgtcacat atcgctttca catctgtttc ttgcaaatct cttagcattt
     6541 caagcctcct caaaagaaat ctctggcaac cgagcaagaa tatcttctcg tttaattgcg
     6601 ccttggcgta agattttcac cttgtctcca gacaaatcca caatagttga atcctgtcca
     6661 gttagaaaag catcgtcttc cagacccaga acctcttggt caaaatcctt cagaatttgt
     6721 tcaaaggtta caccacttgc ctgacctgag atattggcag acggcccaat caagggacct
     6781 gtctctcgaa ttaaatccag tgtgataggg tgactgggca tccgaaatcc aatagttgca
     6841 aggtcagaat ttacccaata gggaactcgg tcattggctt cgagaataat ggtcaaggga
     6901 cctggcaaaa aggtctctac aagtttttgt agataagttg gctgattctt agaaaagtgc
     6961 aagatatcct cgaaagaggc gatattgaga ttgagtgcct tatctctagg acgacgtttg
     7021 agttggtaaa catggtcaac tgctttttca tctaaggcct tggcaaaaag accataaaca
     7081 gtctctgtag gtagaacgac agctccacca ttttccaact cttgtctaat cctgtctatc
     7141 atcaaccacg accatcctat tttgaccaaa ttggtccttg agtgttcgaa ctcttttttc
     7201 aggaagatgt ttcctaaaaa gttcgggaac actttgacct tgcttgtatc caatttcaag
     7261 gtaaatctta ccaccatctt tgagatagtc ttttgcatct tccgcaattc tacagtaaat
     7321 agctaggcca tcctcgtctg caaagagagc tagatgaggc tccgaatgca aaacattcaa
     7381 gcctacctct gactcatctt cacgagagat atagggtgga ttggatacaa ttatatcata
     7441 tttttcagaa atttctgcaa aacaatcaga ttttttaaaa aatatattaa gattttgatt
     7501 gctagcattc tctgatgcaa gctctaaggc ctcttgagaa acatctgctg ctgtcactga
     7561 ccaatctggt ctattttttg ctagagcgag agcaatagct ccactacctg ttccaatatc
     7621 cagaactgag agattcgtct caagattttc agttagaata agctccacta actcctctgt
     7681 ttctggacga ggaatcaaaa cccgttcatc cacctttaaa tgcattccat aaaaatctgc
     7741 ctgtccaatg atgtactgag ctggcttgtg agctgctagt tgctggtaaa tatcttctac
     7801 aaattgtttt tcttcctctg ttgtcacctc ctgctggagg gcaaaaataa agtctgtaaa
     7861 agatagattt ttcagactac gatagacaaa agagaggctt tccgcttcct ctccttgtct
     7921 tatcaactct tcttcaaaat ttgaaaataa ttgagctaat ttcattattt gtttaattct
     7981 tctagttttt gtgtttggtc ataaagcacc agggcatcca caacttcgtc caatttacca
     8041 gacaaaatcg tatctagttt ttggagggtc aagccgatac ggtggtctgt gacacggttt
     8101 tgtgggaagt tataagttcg gatccgttct gaacggtcac cagtaccgat tgtcgactta
     8161 cgctcagcgt cttgttcatc ctgagcaatc tgagcaaagt ggtcagcgac gcgtgcacgg
     8221 ataatcttca tagccttctc gcggttcttc tgctgggtac gttcttcctg catctcaacc
     8281 ttgatattgg ttggcaagtg aacgatacgc acggcagtcg caaccttatt gacgttctgt
     8341 ccaccagcac cagaggcgtg atagatgtcg acacgaaggt cttttggatc aatgtcgtat
     8401 tcaacctctt caacttctgg cataacaaga actgtcgctg tcgaagtatg aacacggcct
     8461 tggctttctg tcacaggaac acgttgcaca cggtgggcac ctgattcata cttaagctta
     8521 gagtatacag actgacctga aaccatagca accacttctt tgaaaccacc gacaccattc
     8581 atagaagcct ccatgacttc aaagcgccag ccttgggctt cagcatactt ttggtacata
     8641 gttagcaaat ctccagcgaa aagtgccgct tcgtctccac cagctgctcc acggatttca
     8701 aggatgatat tcttgtcatc gtttggatcc tttggaagga gcaaaatttt cagtttttct
     8761 tcatattctt ctttttcagc cttggcatct ttgagttctt gcttggccat ttcttccaag
     8821 tccgcatctc cacctgattc cttaatcatc tcttcggcat cgacgatatt ttgaaggact
     8881 tgtttatact cacggtaggc tattacggtg tcacgattgg aggcttcttc ttttgaaagc
     8941 tccataaaac gcttggtgtc tgaaacgaca tcagggtcac tcagcaattc tcctagttct
     9001 tcataacggt cttctacagc ttgtagttga tcatagatgt tcatttttct tcattctcct
     9061 tattgatttc aggggcaaaa taatgtttac ggcaaaccga gatataggtt tcattaccac
     9121 caatctggat ctgttctcca tcgtaaacgg gcagtccatc ctgtgttcgc aacaccatgg
     9181 tcgccttttt cttgcaatac tgacagatgg tcttgatttc gtcaatcttg tccgctaaaa
     9241 gcaagagata tttggaacct tcgaacaatt cattgcgaaa gtcatttttc aagccaaaag
     9301 ccatgacggg tatgtctaac tcgtccacaa cacgagctag gtcataaaca tggtggcgtt
     9361 tgagaaactg ggcttcatcg accaacacac agtaaggttt ttctggtagg tctcggatat
     9421 agccaaagat atccgttgtt tcctcaatcg caagggcagg gcgtttcatg ccaattcgac
     9481 tcgacacata gccaacaccg tcacgcgtat ccagagctga ggtcataatg acaacacctt
     9541 ttccttgctc ctcgtagtta taggccactt tgagaatctc aatcgtttta ccagagttca
     9601 tggtcccata acgatagtac aactgtgcca tgtttcttgc ttcacgtcca tttctaaatt
     9661 tttactacat tctagtatat cataattttc ttaagcttta aacggcaaaa tgtggtaaaa
     9721 tggaagaaat caaaactagt ggaggaagct attatgccat ttgtacgcat cgatttattt
     9781 gaaggacgca cgctcgagca aaagaaagct cttgctaagg aagtaacgga agcggttgtt
     9841 cgcaacactg gagcacctca atctgctgtt catgtcatca tcaacgacat gccagaagga
     9901 acttatttcc cacaggggga aatgcgcacc aaataagcta gcttaagcag aattgcttag
     9961 gctttttcaa tctccaagta gcacccattg aagaaatagt ctaaatttgt tacaatttga
    10021 aaagagactt ggaaaattcc aagaaaagag caattaatta aaggaaacat tatgattaca
    10081 cgtgaatttg ataccatcgc tgctatctct actccactag gtgaaggagc tattggtatt
    10141 gtccgcctga gcggaacaga aagttttgct attgcgcaaa aaatttttaa aggaaaagac
    10201 ttgagtcagg ttgctagcca cactctcaac tacggtcaca tcgttgatcc tctgactggt
    10261 aaagtcatgg acgaggtcat ggtgggagcc atgaaatctc caaaaacctt cactcgtgaa
    10321 gatattatcg agattaacac ccacggtggg attgcggtga ccaatgaaat tctccagcta
    10381 gctatccgtg aaggagctcg attggctgaa cctggtgaat ttaccaaacg tgccttttta
    10441 aacggtcgcg tagatttgac acaggccgag gcggtgatgg atatcatccg tgctaagaca
    10501 gataaagcca tgaacattgc ggtcaaacaa ctagatggtt ctctttctga cctcattaac
    10561 aatacccgtc aagaaatcct caatacactt gcccaagtcg aagttaatat cgactatcct
    10621 gagtatgatg atgttgagga agcgactact gctgttgtcc gcgagaaaac tatggaattt
    10681 gaacaattgc taaccaatct ccttaggaca gcccgtcgcg gtaaaatcct tcgtgaagga
    10741 atttccactg ccatcatcgg acgtcccaac gttgggaaat ctagcatcct caacaatctc
    10801 ttgcgtgagg acaaggctat cgttacagat attgctggta ccacacgtga tgtcatcgaa
    10861 gagtacgtca acatcaatgg tgtacctctc aaattgattg atacagccgg tattcgtgaa
    10921 acagatgaca tagtggaaca aatcggtgtt gagcgttcga aaaaagccct caaggaagcc
    10981 gacttggttc tactagtgct aaatgccagt gaaccactga ctgcgcaaga cagacaactt
    11041 cttgaaatta gccaagatac caatcgcatt attctactta ataaaaccga cctgccagaa
    11101 acgattgaaa cttcgaaact acctgaagac gttatccgta tttcagtcct taaaaaccaa
    11161 aacatcgaca agattgaaga gcgaatcaac aacctcttct ttgaaaatgc tggcttggtc
    11221 gagcaagatg ctacttactt gtcaaacgcc cgtcacattt ccctgattga aaaagcagtt
    11281 gaaagcctac aagccgttaa tcaaggtctt gagctgggga tgccagttga tttgcttcaa
    11341 gttgacttga ctcgtacttg ggaaatcctc ggagaaatca ctggggatgc tgctccagat
    11401 gaacttatta cccaactctt tagccaattc tgtttaggaa aataagaaaa atccatgatc
    11461 cttcattcgg tcatggattt tattgtcttt attagtaatc tggtcttaag acccctgtta
    11521 cagttgcctt agttgcttcg tagtcgccat ctacgacaac cttgataatg cgtttggcat
    11581 cttcttctgg tgctggaaca agaggtagac gagtgggtcc agcttcaaat cccatatagt
    11641 taagaattgc cttaactgga gcaggacttg gataagagaa gagagcatta accttaggaa
    11701 tgaatttacg ctgaattgct gcggctttct tcatatcgct ttctgcaatg gcagtaaaca
    11761 tctcgtgcat ttcatcccca tttgtatgag aggcaacaga aataacccca tccgccccaa
    11821 ggttcatggc atggaaagca tctccatcct cacctgtata aatcaagaac tcttcaggct
    11881 tgtgctcaat caagtaagcc atattagcca agctagtaca ttctttgaca ccgataatat
    11941 ttggatggtc agccaagcga agcatggttt ctggagtcaa ttcgacaact acacgccctg
    12001 gaatgttata gataataatt ggtaggtcag aagcatctgc aatagcctta aagtgctgat
    12061 acatcccttc ttgagaaggt ttgttgtagt aaggaacaat agcaagccca gctgcgaaac
    12121 caccaaattc cgctacttct ttgacaaact caatagagtc acgcgtatca ttagtaccta
    12181 cacccgcaat caaaggaacg cgtccattga caaccttttg tacagccgca aacaactcca
    12241 actcctcatc gtgggtcaaa gttggactct cagcagtcgt tcctgcgaga agaattccat
    12301 ccgtatgatg ggccaataaa tgctcaatca aggctggaat agcatcaaag ttaatggaac
    12361 catcctcatg gaagggggta ataaaggctg taatgatttt acattctttt aaatcttgat
    12421 aagacacgaa aacacctctc tatttcaaag aaggagttca tctgaactcc taaacgatat
    12481 gactatttta attcaaattt caattcggct gttggacgaa ccaatccacg ttcatgaaga
    12541 gtttcagcaa tctgaactga gttccaagca gcacctttga gaaggttatc tgaaacaacc
    12601 cacatgtgaa ttcctttttc tgcatccaag tctttacgga tacgaccaac aaaggtatca
    12661 cgcgaaccaa ctgcattgat ggcttgagga tagatttgat gagctacatc atcttcaaga
    12721 acagcacctg ggaaggctgc gatagctgct tttacttctt cgattggagc cacttctttt
    12781 gtttcgatat aaacagactc agagtgagct gacaagactg gaatacgcac acatgttgca
    12841 gatactgcaa tgctatcatc ttccataatt ttcttagttt ccttggtcat cttcatctct
    12901 tcgtaagtgt aatcattgtc agtgaagaca tcgatttgtg gaagagcatt gaaggcgata
    12961 ggataatgtt tcttgtcacc gcctgaaggt aagatttccg catgcaaatc acgtggtttc
    13021 actccatcat tcaagacctc acgaagttca cgttgtgtct caagaattgc tcccatacca
    13081 gcacctgaaa cggcttgata agttgaaaca atgatacggt ccaagcccca tttttggcga
    13141 accggctcaa gagccaccat catttggatt gttgaacagt tagggcaggc aatgattccg
    13201 ttgtgggcat caagtgcatg agcattgacc tctggaacaa ccaaaggaac atctggattt
    13261 tgacggaaat aagatgtatt atccactact accacgccag cttttactgc gtatggtgca
    13321 tacttagctg atgtcgaacc acctgctgaa aagagagcaa tatcaactcc ttcaaaagct
    13381 gtttcagtcg tttcttcaat cgtaatatct tgatctttaa atttcaatga cttacctgct
    13441 gaacgtgcag aagcaaggta acgaatttta tcgattggaa gtgttgattc ttccaacatt
    13501 tttatcatct gagcaccgac agcacctgtc gcgccgacta cagcaactgt atatcccata
    13561 aataacctct ttcggaattt tctaaaaatt tctataatag aagtattata ctactttttc
    13621 catgaattgc aaagcttttt catcattttt tggaaaataa aaatcccagt cgctagacta
    13681 gggactaaga ggcatcttca tgtgatgagc aggttcacac aactcatcaa ggtccgctcc
    13741 tgcgttatga cctccttatg ctcaatagta gtccgaagac tacctatcga ctcatcgcat
    13801 attctatatt actagagata cttgattttg tcaataagaa attttttcga tcgagtataa
    13861 caaaaaactc tcgtattcaa gagtttccct atacatatca tgctaattgc cgggatcgaa
    13921 ccggcgacct catccttacc atggatgcgc tctgccaact gagctaaatc agcttactta
    13981 agaagtatac tatattcaga aaaacttgtc aagtttcctt agaaattttc cataggaaaa
    14041 agccaggtaa gaactaccta gcttatcttc ttctatttac ttaaatcaat tcgacgacca
    14101 attttaccaa taataatcgc cccaataatc aatgaagcaa attcaccgat tcctgttgta
    14161 aaccaagtaa ggaagaatgg taattctgct acaatattta actctgcagc gatagtaaac
    14221 atggaaattg aaaagaggat tgaaaagaag aaatgatctt ttcgaatcaa tccgttaaag
    14281 aggtaatcct tgctatattt tgcaaaaagc caaacaccta aactgaggaa tactaaggtt
    14341 gaaccaccac caacaaagac atctagcagt ccgaagctaa agaaattagc aatcatacaa
    14401 ccgatggtaa ctccgatgat gtacttagga ttgtaaaaag ccataaagtt catcatttct
    14461 gaaatacgaa actgataagc accatagctg atggcattta ggggcggtgt gacagtcaaa
    14521 acgacgtaga tagcagcgac gattgcaata tctgcaacat cacgaatagt taattttttc
    14581 atcttttctc ctttggcggt tgcccgcgtg taatatgctt ggtgaaagaa gctaagcacc
    14641 aagggttgat tcattcaacc ttactagtat agcacaatag cctgctttat gctatactta
    14701 aagcatgaaa aaacctattc aaaaattttt taacaatgaa atcttagcct atctcttttt
    14761 tggtatagtg actactcttg ttgctatact atcacgatta gtcatttatc agctaagtca
    14821 tcaggaactc cttgctacgg ccttggcaaa tattatcggt attttatttg cctttatcac
    14881 aaatgatacg attgtattta agcaaaaaaa gaaaaataga cttatccgtt tagtgaaatt
    14941 ttctcttgct cgcctttcta cttttctgtt agatttgctc tttacttttc tctttgtgac
    15001 tcagtttcct cacatcatag ggcaattcgt aaatgaaaac attgataaga taaatgctat
    15061 tgaaacaata attgcacaaa tactcattat tatcatcaat tatatcttga gcaagatcta
    15121 tatttttaga aaataatgct ccatttatga gccttttaat tgccttctat aatgatttag
    15181 gatacaatga aacacgaaac attgaaagga aaacagtatg ttaaaagatc ttaaatcatt
    15241 cttgcttcga ggaaatgtta ttgaccttgc tgtcggtgtt gtcattgcct ctgcttttgg
    15301 tgctatcgtc acttcgcttg taaacgacat tatcactcct cttattttaa atcccgcttt
    15361 gaaagctgct aaagtcgaac gtattgctca actttcttgg catggagtcg gctatggtaa
    15421 ctttttaagt gctattatca attttatctt tgtcggtacc gccctcttct ttattatcaa
    15481 gggtattgaa aaagcacaga aactgactgg cataaaggaa gaaaaaactg ccgaaaaaaa
    15541 accaaccgaa ttggaagtcc ttcaagaaat aaaagctctc cttgagaaaa aataatcgat
    15601 taaaaggatt tagcgcaaag ctaaatcctt ttttctttac tctttgggta acttgcctgc
    15661 tttttcaagc atttttttga taagataagg catcttaaca ttctcccgcc cttttttctc
    15721 aatcagtttt ttcacaaatt ctggcatttg taaatcttca gattcagcta aaatgttttt
    15781 cgtctcgtct gaaggaacta actcatcaaa ggtctcttct tctgggagaa attccttaaa
    15841 ctcttgattt tcattgactc taactgtatt gaccaaagca tcaatcaaac gagaatctgt
    15901 atttggcatt ggtggacgat ggtagtttac cccaaattcc tggcataagt cataacattc
    15961 tacatcattg tcaaacaaga cctcaatatg ctcactgatg aaactaatag gtacaaaaat
    16021 ataatggtct ggatgttctg tctgttctct gagatactcc aaaacatctg gtttaatcca
    16081 tggaatacca atatcactct cactctgcca agtgttggta tattgttctg aactcaagcc
    16141 cagtttttca gcgactagct tgctattttc gaaaatttgg tctatataag gatcaccaaa
    16201 gtccaaggca aaaatgggca cactatgggc tgaaaagatg actttaaagc tgtcttgctt
    16261 tacttcttct tttaaaatct tagcaatttc atctgcccaa tagtttaaga gcgcttcttc
    16321 ctgataccag tccttaatga ccaaaaattg aatttgtttg ctttctaaaa atttttcata
    16381 gcccatgaca gagtagaaag aataatgggg ctccaaaatc aagcaaatac actgttcaat
    16441 tccgtctgct tccatttgac cgatcacatc tggaataaag ggactggaaa acttattagc
    16501 aaagtagaca ctgtattcat tccccagcct agcttctacc aaggcaacct cttgacgggt
    16561 aattttttgc agaggcgtgc ctccaattcg tacataatta tcatagagag tctgaatctc
    16621 gtggtcttgg ggtctcaccc cacgacgaat atttgtgaaa aaatcagcta caccttcaaa
    16681 ggtaatctct tctggtgaac cgaaggtcat cattaaaatt gcttttttca tgactgcttc
    16741 cttgtgatgt ttttatcaag tttattttat cattaattca tcgataagta aacgctaaca
    16801 tagggacatt ctcaatcttc tgtcttttgt ttttctcttc tttctatgat acaatggaaa
    16861 aaataaattc aaaaggagtt tttttatgac ttatccaaat ctcttggacc gcttcttaac
    16921 ctacgttaag gtcaacacgc gctctgatga acactctact actactccaa gtacacagag
    16981 tcaggttgac ttcgcaacaa atgtcctaat tcctgaaatg aaacgtgttg gactgcaaaa
    17041 tgtttactat ctaccgaatg gttttgctat tggaaccttg ccagccaacg atccgtcttt
    17101 aacacgtaag attggtttta tatcgcacat ggatactgct gattttaatg ctgaaggagt
    17161 caatccacag gtaattgaaa actacgatgg tggtgtgatt gaactaggga attctggttt
    17221 caaactcgat ccagccgact tcaagagtct tgaaaaatat ccaggacaaa cgctcatcac
    17281 aacagatgga acaagcttac taggtgctga tgacaagtca ggaattgctg aaattatgac
    17341 agccattgaa tatctaactg ctcatcctga aattaagcac tgtgagattc gtgttggttt
    17401 tggtccagat gaagaaatcg gtgttggtgc caataaattt gatgcagaag attttgatgt
    17461 ggattttgcc tacactgttg atggtggtcc actaggtgaa cttcagtacg agactttctc
    17521 agccgctggt gctgaattgc atttccaagg ccgtaatgtc caccctggta ctgccaaagg
    17581 gcagatggtc aatgcccttc agctagcaat tgattttcat aatcaacttc cagaaaatga
    17641 ccgacctgag ttaactgaag gttaccaagg tttttaccat ctaatggatg tgacaggtag
    17701 tgttgaggag gtgcgtgcaa gctacatcat tcgtgatttt gaaaaagatg cctttgaagc
    17761 gcgtaaagca tccatgcaat ctatcgctga taagatgaat gaagaacttg ggagcgaccg
    17821 tgtcactctc aacttgacag accagtacta caatatgaaa gaagtcattg aaaaagatat
    17881 gactccaatt accattgcta aaaccgttat ggaagatcta ggtatcacgc ctattatcga
    17941 accaatccgg ggtggaacag acggctctaa gatttccttt atgggaatcc caactccgaa
    18001 tatctttgca ggtggcgaaa atatgcacgg acgttttgaa tacgttagcc ttcagactat
    18061 ggaacgtgca gttgatacca tcattggcat cgtagcttat aaaggctaaa aagacgaggt
    18121 ggctcagcta cttcgccttt ctttttattc tactggtttt tcttgatttc cagtagttgt
    18181 agaagattct gttgttttat tttctgaagt tgattcagca ggtttagaat ctcttgtatt
    18241 gcttggtttg ttttcgtcgc tagcagtttc aatgttagat tctgcagttg cgtttggttg
    18301 gttctcagca ctggtgttat caccatttgc ttcagcattt cttgctggac ttgtttcttc
    18361 acttgcgcta gcttttgact ggatttgatg attcaaaact agaatagctt ttgtcgattc
    18421 aagtaaagct gttttgtctt tactcttagc agaaagttga tctaataatg catccacctt
    18481 atcaaagtcc gcatcagatc cattattact ttctaaataa gagtgaagcg acatgagaat
    18541 atcgtagagt ttttgataga gtacaagtgt ctgaggatct tgctcagcat tttccttttc
    18601 ttgttgaagg gcgctagcga tacgagtcaa aacatctttt acctgactgt ttacttcatc
    18661 caagtctgca tcagccttgt ttgtggcagc ttttagattt tctacttctt ctgccaagga
    18721 ttgtctgatt ccttcttcat ggatttgttc caagagttga tttgccttgt tcaaaagact
    18781 ttctacttct tccttgctat ctgtcgcaga ttattggttg ctatctacca tgtactccta
    18841 aaacaggaga gttataatcc aagattacaa ggccttacag aaataagaaa tccagataag
    18901 acaatgttcg tccaagacgc tattcgcttc gcacagcagc acggattcaa tatgctttaa
    18961 ttttaaagtt taggtgtcaa gacctctttt tagtgtgccc aaaatttaga gaagtaatca
    19021 atcaactaac ttttattttt ttcaaacttt cagtaaactg acctaaagct aactcaatct
    19081 gtctttgtag atgcttctgc tatcagctag aagttgatct acttttgcca agactgtctt
    19141 ctcatcaaaa gttccaggtt gatagttgga ttgcagggat ggaatcttgt ttttcaaagc
    19201 cgcttcatat cccttagttt gaaccttgat gtagtgattg tggtcgccat gaggaatcac
    19261 aaaaccttct gaatcttcac ttataattcg attagcatca aaaaccatga ccatcttctt
    19321 cctcatggtg gacatgtagt gacggattac ttaatacaga actagaagaa cttcctacct
    19381 cttccgtgtt agagtgtgat gggggattgt taagagatga cttaggaata tagtgatagt
    19441 gttccccatg tcttactata taagcatcac ctatatctct gacaatatca ttagggttaa
    19501 aaacatatgt ggctgctaat tcacctgccg acaagtcact ctcaggaatg aaatgatagt
    19561 gaccaccatg tggtactata gtaggttgaa atagaatatg agcaaattga taaggggatt
    19621 ttaaagtaat ttctaacaat gatttagaaa ctatgatgtg ctattctaaa ttcaactcac
    19681 tatatataac catcatcggt agtataacgt ccctgtaatt ttgctacaga tacttctgca
    19741 ctagctcctt tatcgtcttt accatgttct tgtttttggc gattgatttc atcttttgtt
    19801 cgtacatttt ctgcatgagc ttaatcttta aggtaaacat aatactttcc atctacctta
    19861 atactatatc ctcccttaac ctaactgacg atatcttgat ctttcggctg atagttgggg
    19921 gctttcatta atggctcttc actaaagagc gcatcaaaag gaactttacc attatagcag
    19981 tgataatgat cgccatgaga agttacataa ccttgacctg taatcttaat aacaatttgt
    20041 tttgcttgaa ttccttcttt ttgactaacc tagtctggag tcaaattttc agtcttctta
    20101 gtgtctttat tactgtttac atatgaaaca cgatttttat ctgtattggc ctgttagcta
    20161 tgttggttca gagcataaac acacagactt aaggaaagga taacaacaga tccagctgct
    20221 atatatttct ttttaaattt ca
//
LOCUS       DAVMAH010000040        20026 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVMAH010000040 DAVMAH010000000
VERSION     DAVMAH010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20026
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.040"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            160..378
                     /locus_tag="VYO94_001443"
     CDS             160..378
                     /locus_tag="VYO94_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1760070.1"
                     /translation="MTSRFDISWVQDILQVFSSKLADLLLAGVDTSVMRIRFVNILKE
                     YKYLCETYNLTHTDEYREILFRLDLYRE"
     gene            467..1345
                     /locus_tag="VYO94_001444"
     CDS             467..1345
                     /locus_tag="VYO94_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000347542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HEV1760071.1"
                     /translation="MDLNVPINFQGNYHQVEISEGALLQIGQGVTMRSFTSLEVNEGA
                     KLSIGDRVFFNDHCSIRCGKEIEIGKDTMFGDGVRIFDSNHRYSNYHVEKLRFNCEKI
                     TIGNNCWIGSNVVILKGVSIGDNVIIGANALIYRDIPADSIVTSEQNLRITPRKNYYY
                     HAFTLTASDTLEELEFLVTELSDVAFHIVAKTNISPYLEKFDQFDNVNLYTNIHHNDI
                     IEDLLTRSDIYLDINHWEEVDGIVGRAIEKGKKIFAFSNVVHRISDDIQVFKIEEKNK
                     MVEAIRQQLEKDDNGD"
     gene            1348..2595
                     /locus_tag="VYO94_001445"
     CDS             1348..2595
                     /locus_tag="VYO94_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV1760072.1"
                     /translation="MIGNNIQSKKAIALGADSNYMDKVETTIKSVCSHNRDIKFYIFN
                     SDFPTEWFQLMNKRLAVLNSEIVNVKITDDTINHFNLPTPHLSSAAYLRYFILNFVNE
                     KRILYLDSDIVVTSSLVSLFESSLDGQPMGAVPDLPNTYDGFNSGVLVIDTDMWRKEN
                     ISKKLLDLTVEHHEHVYGDQEILNMFFKDRWKQFDLTFNLQVGADAHQYYMGDYDWYE
                     SFEGVPCIIHYTTENKPWKHFRFNRFRDIWWFYYGLNWNDILLRTHVLKETFAELISP
                     ISQHASIFTNTGDIEGIGYLLEKLPDVQFHIVAPTYFSPNIIELQRYSNCYIYPCADP
                     KMKQNIIDKTDIYLDINYGLGMDQELQEMARQGKAIYSFDSTNHFSNGESTVFTVGEI
                     DELIRKIEELGDNNESKSDCSWS"
     gene            2564..3793
                     /locus_tag="VYO94_001446"
     CDS             2564..3793
                     /locus_tag="VYO94_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEV1760073.1"
                     /translation="MNQKVIALGADIHYLDKVETVIKSVSVHNHKVKFYVFNDDLPSE
                     WFLLMRNRLKVIGSEIINVKKADHNLRDFHLPNAILSYAAFFRYFIADEVIEDRVLYL
                     DSDTIVNAKLDDLFFLDLQGYSIAAVQDFDQDGWLTTFNAGMLLIDAKKWREKKSTQN
                     LLELTAQHHEHVYGDQGVLNIYFGDQWLHLDKEYNFMVGLDQFLHLKGNADWYQSNYY
                     GNYEPKIVHYTAEFKPWTHLTLTRFRKLWWFYYGLNWNDVLLSSDIVKRSFKELVGVP
                     LYHTCIFTNSAAMESLEYLLSELPEVHFTILAHTNFAPSVVDLQRYLNLSLFPNFNSF
                     NMKETLDKMDFYLDINHEGEIVNIIEEVHRRNKPIFAFDNTSHDSSGRSHIFSASEPD
                     KMVDTIRTFLGEEVNGK"
     gene            3783..4625
                     /locus_tag="VYO94_001447"
     CDS             3783..4625
                     /locus_tag="VYO94_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1760074.1"
                     /translation="MGNELISIIVPIYNVENYLRMCLDSIQNQTYQNFECLLINDGSP
                     DNSAEICREYVAKDSRFRYFEKENGGLSSARNYGIERAEGTVITFVDSDDWLEGNSLE
                     ILYDKMNQYDADVVVSCYCIYDEEKETFLFFTYGETYDKIYSTKELLEMLPVLEGKTL
                     SFQTSWGILFKKELFEHISFPVGKINEDIATNYKCYMQAKKIVYAHKNTYCYRLRNTS
                     ISHASFTEKMMRDDHDARIERIALLALKGYDISNYLTQHKQYLKAWHAHAIDIAEKQL
                     VWRN"
     gene            4821..8054
                     /locus_tag="VYO94_001448"
     CDS             4821..8054
                     /locus_tag="VYO94_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HEV1760075.1"
                     /translation="MKAIVLAGDKNYLTPMLTTIKSILYYNQQVKIYILHQNIPSDWF
                     HELKIQVEKLGSVVEGIYIGDTIDVEWKTQEHISPIAYARYLIPRLIKEERVIYLDSD
                     IIVNGDLSSLFELDFGDYSIAAVRDADGNGFNSGVLVIDSQKWREKDVTSILFDKTVE
                     YMSYLDHTDTDRFNGDQTIFNLVFQNHWLELDKRFNLQVGHDVIAFYSHWDSHFELDE
                     EPLIIHYTTYRKPWTTLMGYRYRDLWWSFHDVTFDQISDHYQGRFAVKRVYDFHDINL
                     FTFTDSQDFLYIEELAQTLPNIGFHIGAYTDMGDILLALDKYPNVYLYPSMVGAVIDE
                     MIEKSDAYLDIHKGSQMNFIVNRYTSADRPVLTFDVTNKNQLEQIVISSQSPQPMIEA
                     IKELKKDKMDMKAIVLGANYQYADKVLTTIKSICCHNRGLRFYLINSDFPTEWFYNLN
                     RKLKELDCEIVNARVNSSHISQYKTNIHYTTFLRYFISDFVEEDKVLYLDCDLVVTRD
                     LSPLFDVELGDYPLAAVKDLGAQVYFNEHGFNAGVLLINNRLWKQEEVRKQLIEMTNE
                     LHDKVAQDDQSILNLLFKDRWLVLDFKYNCITLHTHFSDYRPESGTYPPIIHYLTERK
                     PWGLYERSIYRDVWWYYNAQDWSDIGEATPCLTKDQVSQYTGVQHSGVQHSAFIYTFS
                     CDLRNIECLIEGLPNVKFYIAAPVMVADSITDLLAYPNVSVLSDIAGQPPLIDSLVEG
                     CDFLLDINADIEVDGIIERFRQAGKPVFAFESVVHGEQGQFLYDQAHPEEMVLAIEAY
                     CQNGELPVKKLKSYPKVLDIQQSLDYILEHHFSVIRYGDGEMDIMMGHGIPYQDYDEN
                     LAEQLRSMIQLESSPELLVCLSDVFEGLERYNPEAVNFWQEHLEHYKEAYHRFCTASF
                     YGSTFISRPYMDLKDKTASVAHFEKLKQLWDERDILIVEGENSRSGVGNDLFDNARSV
                     ERIICPSRNAYGKVQVIQEAVEKYADGKLVFLMLGPTAKVLAYHLSQKGIQAIDLGHV
                     DSEYEWFKMGATSKVKFSHKHTAEHNFDQEIQFVEDEIYNKQVVVRI"
     gene            8063..9070
                     /locus_tag="VYO94_001449"
     CDS             8063..9070
                     /locus_tag="VYO94_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1760076.1"
                     /translation="MKINITNIYGMSGQSTALIAQNETVKIAKKLDFHELSFYFYNIY
                     SDSEGELNSRLDGVLAKLGYGDIVVYQSPTWNGREYDQNFIRKCKILNTKMITFIHDV
                     PPLMFPSNYYLMPEYIEMYNQSDLVVVPSEKMKERLIQEGLTVQKIIIQGMWDHVHNY
                     PLKQPSFQKKLYFAGSVERFEHLSNWAYSTPLDIFSESNYENSNPRVSFKGWKTDPEL
                     LFALSEGGFGLVWGTSENPADEEDYYRLNISHKVSTYLAAGIPVVVPSYLSNASFIKE
                     KGLGYVVDSLEEANRLVEETTAEFYQQMVKNVSKVSYALKEGYFTKKLLIDAVMQLLD
                     I"
     gene            9178..10404
                     /gene="secY2"
                     /locus_tag="VYO94_001450"
     CDS             9178..10404
                     /gene="secY2"
                     /locus_tag="VYO94_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HEV1760077.1"
                     /translation="MKKKLKSVVVKRVMWTICFIFVYILGSRLTLPFVNVNDTSFLGG
                     NAAFLAFSTAMTGGNLRSLSLFSVGLSPWMSAMILWQMFSMSKKLGLGNLPLEIQERR
                     KMILTFIISFIQTLAITLNLPIQEGVNHDLVLILNILLLISGTFFLVWLSDLNSLLGV
                     GGSVVILMSSMIVSVPENIVRSIIDLHVNLLFIISLLLISIAFLYIAVRVQKARYRIL
                     VNKIMIHNRFKRYSYFDIMLNPAGGMPFMYAISLVSIPQYLLMLLHIFVPKTRWVDNW
                     IAEFTIGRPVWVYTYIIVLFLLGIAFAFVNMNGEQIADKMKKSGEYIYDIYPGEDTAL
                     YINRLVLRFAVIGSIYILLMAGIPMLIILYEPRYMQLSMLPGLFLMFNGMIFNVKEEI
                     NALTLNESYRPLVERK"
     gene            10693..12267
                     /gene="asp1"
                     /locus_tag="VYO94_001451"
     CDS             10693..12267
                     /gene="asp1"
                     /locus_tag="VYO94_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HEV1760078.1"
                     /translation="MYYFIPFLESMNQSWQVDIVPWYQTTHRLEFDDVLHQIRIFKRE
                     GIKSKIVLLPYHPHMRYLLHRQDLLEVEAFSVFDAIQDIENEEIYPLQLKDLAWDEDC
                     DFIYTPFLIAVKQKGELHAHIEFGTEGFISYITYFKDNQVDFICYFDDRGFLSSLVKY
                     QDNQAVSRYYYNSNAEWQIKEYLQGIHTKVEVNPRFSHRFRKSTYQSVDEVVWEFFEK
                     FLTAEYKEGESFVLAAQTKYQNQLLKHLPEHADKILTFFIERNQEDDLNLHHQAVKQA
                     KILISDRQDFLERLKQHYPQFTYKMHHLPSFDTRLKLGVSQRVKESKLYVQLDLNTPF
                     NSEALYEVLNFVSQNPLTEIVFATFNAEGYQIEALQKHLFTLISERLNFRDLLKESII
                     SGAENKLEENKEENYRFQIVNLNDEIGLIRELEYTRLIVDLNPIANIYTQIAGISAGI
                     PQINLSESEYVTHLQNGYILSDLSEFSKAGHYFLDTLEHWNQALIHSIDKIRQNTGNQ
                     FVQKWERWLEEAKSEQ"
     gene            12257..13789
                     /gene="asp2"
                     /locus_tag="VYO94_001452"
     CDS             12257..13789
                     /gene="asp2"
                     /locus_tag="VYO94_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HEV1760079.1"
                     /translation="MSNKLHILQIGNRNWSHYYEIPENIEWHFFWPGSTTAIKKVMKM
                     EGIRTFSGVVIENPDYLPDLLPLINILTPYTIFYSDICASYSPLVEEFLKKTCAQVTD
                     FSNPRELLRILSKALFKGQYGDKLTPIDMVVNPYFAGSIRYNGYENLELVGSYGEDFR
                     PLISWKYNIRASEWNPIELWLEYEKDLSCDIRIVVRNIQDGSTADFIKERIFTTDDME
                     AAILLDDDFSSFISVSLEAKGNGRLKIGALHQRLTRYQFGKFVLGGNIIRSKNREEIN
                     YFFYPGDFKPPLNVYFSGYRRAEGFEGFGMMKSLGSPFLLFQDPRIDGGAFYLGDDDF
                     ENAVRRVIQHHLDLLGFSNKELILSGISMGTYGALYYSSDFEPKAVIVSKPLTNLGLI
                     AERGRLEAPGLFPTAFDILRHHSQGKADIDSINILNARFWERFRGADFNQTIFGLSYM
                     KEEDYDPIAYDSLVDSLYSTGARIMVKGTSGRHNDDNDSTILWFVNFYKMVLEQEFGR
                     KY"
     gene            13789..14268
                     /gene="asp3"
                     /locus_tag="VYO94_001453"
     CDS             13789..14268
                     /gene="asp3"
                     /locus_tag="VYO94_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HEV1760080.1"
                     /translation="MVIRRQKEIFWGEFKGASLGNLRENSFLYGSIVIYYARNHIYFE
                     NEMISSGTMVHEWTSSFNFQGNRLTPTLPLIKKGHRYRLTSNMTIKPDNGLYFRLIFK
                     DRYDEKVSQLIKKDLTFTFTYPEEAYNYSIQLLSAGLKSVDFHSFSIEEDYTEQNVE"
     gene            14258..16633
                     /gene="secA2"
                     /locus_tag="VYO94_001454"
     CDS             14258..16633
                     /gene="secA2"
                     /locus_tag="VYO94_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HEV1760081.1"
                     /translation="MWNKNRQLRKVKKILNQINRRKEEMALLTDEELAAKTQEFKRRL
                     TAGETLDDILVEAFAVVREADKRILGMFPYDVQVMGGIVIHQGNVAEMNTGEGKTLTA
                     TLPIYLNALSGQGVILVTTNSYLAKRDAEEMGKVYEFLGLTIRLPFADDEEEKITPKE
                     KKEIYSADIVYTTNSGLGFDYLIDNLASSEEQKYMPEFNFVLVDEIDSVLLDSAQTPL
                     VISGSPRVQSNFYGIIDTLMTTLVDGEDYIFKEEKKEVWLTNKGAKIAEKFLGIDNLY
                     AEENNVLARHLVFALRAHTLFKRDKDYIIRKGEKDQELVLLDQGTGRLMEMTKLQGGL
                     HQAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVR
                     IPTNRPRQRIDYPDNLYITLPEKVYASLEYIKEYHAKGNPLLVFVGSVEMSQLYSSLL
                     FREGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIV
                     IGTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQD
                     MTQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDG
                     SRDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVR
                     SFMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQS
                     ASQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            16645..18156
                     /gene="gtfA"
                     /locus_tag="VYO94_001455"
                     /pseudo
     CDS             16645..18156
                     /gene="gtfA"
                     /locus_tag="VYO94_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
     gene            18149..19486
                     /gene="gtfB"
                     /locus_tag="VYO94_001456"
     CDS             18149..19486
                     /gene="gtfB"
                     /locus_tag="VYO94_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HEV1760082.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QERLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIAGALPDVTFRIAAVTEMSSKLLDMLRYPNVFLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQETMQTVLGG"
     gene            19488..19667
                     /gene="asp4"
                     /locus_tag="VYO94_001457"
     CDS             19488..19667
                     /gene="asp4"
                     /locus_tag="VYO94_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HEV1760083.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            19672..19896
                     /locus_tag="VYO94_001458"
     CDS             19672..19896
                     /locus_tag="VYO94_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HEV1760084.1"
                     /translation="MIEILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLIFMVITYK"
BASE COUNT         6345 a         2995 c         4162 g         6524 t
ORIGIN      
        1 tttaagttgt tcaaaaaaga tttgctattg caagttccat ttactaatgg tcggcgcttt
       61 gatgatgaag caacgattca tagattgttc ataaaaagtc agaaaacaat tttcgtaaat
      121 gataatcttt atatctatcg tgttagacaa ggtagtatca tgacttcgcg atttgatata
      181 tcttgggtac aggatatctt gcaagtgttt agttcaaaac tggcagattt gcttcttgcg
      241 ggtgttgata ctagtgtaat gcgaatccgt tttgtaaata ttttgaaaga atataaatac
      301 ttatgtgaaa cctataattt gacacatact gatgagtatc gagaaatttt atttagacta
      361 gatttgtata gggaataggg agtaagaaat agctattgag gttacctagg attgtagtgg
      421 ggaaattgga accatgttgt agtcttaatg tttataggag gtagaaatgg acttgaacgt
      481 tccgattaat tttcagggaa attatcacca ggttgaaata tcagaggggg ctcttcttca
      541 gattggtcag ggagtaacga tgcgttcttt tacaagttta gaggtcaatg aaggagctaa
      601 gctcagtatt ggcgataggg tctttttcaa tgatcattgt tcgattcgtt gtggaaagga
      661 aattgaaatt ggcaaggata ccatgtttgg agatggtgta aggatttttg atagcaatca
      721 tagatactct aattatcatg ttgaaaaact tagatttaat tgtgaaaaaa taacaattgg
      781 taataattgt tggataggaa gtaatgtagt aatattaaaa ggagtttcga ttggggataa
      841 tgtaattatt ggagctaatg cattaattta tagagacatt ccagctgatt caattgttac
      901 ttctgaacaa aacctaagaa ttactcctag gaaaaattat tattatcatg cttttactct
      961 gactgcatct gatactttag aggagctaga atttttagtt acagaattat cagacgttgc
     1021 atttcatata gtagctaaaa caaatatttc tccttattta gaaaaatttg atcaatttga
     1081 taatgtcaat ctatatacaa atattcacca taacgacatc attgaagatt tattgactcg
     1141 ttcagatata tatcttgata ttaatcattg ggaagaagta gatggtatcg tgggtagagc
     1201 tatagaaaaa ggaaagaaga tatttgcttt ttcaaacgta gttcacagaa ttagcgatga
     1261 tatacaagtt ttcaagatag aagaaaaaaa taaaatggtt gaggcgattc gtcagcaatt
     1321 agagaaagat gacaatggag actagggatg atagggaata atatacaatc aaaaaaagcc
     1381 atcgctcttg gagctgatag caattatatg gataaggtgg aaacgacgat aaagtcagtc
     1441 tgtagtcata atagggatat aaaattttat atcttcaaca gtgattttcc tacggagtgg
     1501 tttcaattga tgaataaaag gttagccgtt ttaaattctg aaattgtgaa tgttaaaata
     1561 acggacgata caatcaatca ttttaatctt cctacaccac atcttagttc tgcagcctat
     1621 cttagatatt ttattcttaa ttttgttaat gaaaagagaa ttctctatct tgatagtgat
     1681 attgtggtaa catcttcttt agtgtcatta tttgaaagtt ctttagatgg tcaacctatg
     1741 ggagctgttc ctgatttacc taatacttat gatggattta attcaggagt tcttgttatt
     1801 gatacagata tgtggcgtaa ggaaaatatt tcaaaaaaac tccttgattt gaccgtagaa
     1861 caccatgaac atgtttatgg ggatcaagaa attttaaata tgttttttaa agatagatgg
     1921 aagcagtttg atttaacgtt taatttacag gttggtgctg acgcccatca atattatatg
     1981 ggagattatg attggtatga atcatttgaa ggtgtcccgt gcattattca ctacactaca
     2041 gagaataaac cgtggaaaca ttttcgattt aatcgttttc gagatatctg gtggttttac
     2101 tatggtttaa attggaatga tattttatta cgaactcatg ttttgaaaga aacatttgca
     2161 gaattgattt caccaatatc tcagcatgct agtattttta ccaatacggg agacatcgag
     2221 ggaatcggtt acctacttga aaaattgcca gatgtccaat ttcatattgt agctccaaca
     2281 tatttttccc ctaatattat cgagttgcaa cgctattcca attgttacat ttatccatgt
     2341 gctgatccta aaatgaagca aaacataatc gataaaacgg atatttatct ggatattaat
     2401 tatggattag gtatggatca agagttacaa gagatggcgc gacaaggaaa ggcaatttat
     2461 tcatttgatt ctaccaacca tttttctaac ggagaaagta cggtctttac agttggtgag
     2521 atagatgaat tgattagaaa aatagaagaa ctgggagata acaatgaatc aaaaagtgat
     2581 tgctcttgga gctgatattc attaccttga taaggtagaa accgtgataa agtctgtatc
     2641 agttcataat cataaagtga aattttatgt gtttaatgat gatttaccta gtgaatggtt
     2701 tcttttgatg agaaatcgtc tgaaggttat tggttctgag attattaatg tcaaaaaagc
     2761 agatcacaat cttcgtgatt tccacttgcc aaatgcaatc ctgtcctatg ctgctttctt
     2821 tagatatttt attgcagatg aagttataga agatagggtt ctctacttag actcggatac
     2881 gattgtcaat gcaaaattag atgacttatt tttcttggat ttacagggat attctatcgc
     2941 agctgttcaa gattttgatc aagatggttg gttaacaaca tttaatgcag gtatgttatt
     3001 gattgatgca aaaaaatggc gagaaaaaaa atcaacacaa aatttgctag agttgactgc
     3061 tcaacaccat gaacatgtct atggggacca aggtgttctc aatatatatt tcggtgacca
     3121 gtggctacat ttggacaaag agtataattt catggttggt ttagatcagt ttttacattt
     3181 aaaaggtaat gctgactggt accaatccaa ctattatgga aattacgagc ctaagattgt
     3241 ccattatact gcagagttca aaccgtggac tcatttaaca cttacacgtt ttcgtaaact
     3301 ctggtggttt tattatggat tgaactggaa cgatgtgttg ttaagttcag atatcgttaa
     3361 acgctctttt aaggagttag tgggtgttcc cttatatcat acttgtattt ttacaaatag
     3421 tgccgcaatg gagtccttgg aatatctcct atcggaattg ccagaagtgc actttacgat
     3481 cttggcgcat acaaattttg ctccctctgt tgttgattta cagagatatc tgaatctttc
     3541 actttttcca aattttaatt cttttaatat gaaagaaacc ttggataaga tggatttcta
     3601 tcttgatatt aaccatgaag gagagattgt caacattatc gaagaagtcc atagacgcaa
     3661 taaaccgatt tttgcttttg ataatactag ccatgattcc agtggaagaa gtcacatttt
     3721 ttcagcaagt gagccagata agatggtaga tactattcgc acatttttag gagaagaagt
     3781 taatgggaaa tgagttaatc agtattatag ttccaattta caacgttgag aattatttga
     3841 gaatgtgctt ggatagcatt cagaatcaga cgtatcaaaa ttttgaatgc ctattaatca
     3901 atgatggttc tccagacaat tcagcagaaa tctgtagaga atatgttgct aaagattctc
     3961 gtttccgtta ttttgaaaaa gaaaatggtg gattatcgtc ggctcgaaac tatggaattg
     4021 aacgtgcaga aggaactgtt attacttttg tggattcgga tgattggttg gaaggcaata
     4081 gtctagagat tctatatgat aaaatgaatc aatatgatgc agatgttgta gtatcttgtt
     4141 actgtatcta tgatgaagaa aaagaaacat ttcttttctt tacctatgga gaaacgtacg
     4201 ataagattta tagtactaaa gaactactag aaatgttacc agtattagaa ggcaaaactc
     4261 ttagttttca aacttcttgg ggaattttat ttaaaaaaga gttgtttgaa catatttctt
     4321 ttcccgttgg aaaaataaat gaggatattg cgacaaatta taaatgctat atgcaggcga
     4381 agaaaatagt ctatgctcat aaaaatactt actgctatcg tctgagaaat acaagtattt
     4441 ctcatgcatc gtttacagag aaaatgatgc gtgatgatca tgatgctcga attgaaagaa
     4501 ttgccttatt agcattaaaa ggctatgata tcagtaatta tttaacgcaa cataaacagt
     4561 atttgaaagc ttggcatgct catgctatcg acatagccga gaaacagctc gtttggagga
     4621 attagatttt cttctttctg aggaagacta accatccatt ttttactggc aggttagtcg
     4681 cagtggagct aaagtcgtag taaaatacga aagctatgtt ttcttgtgct tctgtgatag
     4741 taagcgggat tccaaggaga agaaagtgat gaacttttgt taggcagttt taaaataaga
     4801 acagagataa aaggatttat atgaaagcaa ttgttcttgc tggagataag aattatctta
     4861 ctccaatgct tacgacgata aagtctattt tgtattataa tcaacaggtt aaaatttata
     4921 ttctgcatca gaatattcct agtgattggt tccatgaact taaaattcaa gtggagaaat
     4981 taggtagtgt tgtggagggt atttatatcg gtgatacgat tgatgttgag tggaaaacac
     5041 aggagcatat ctcacccata gcttacgctc gctacttaat tccaagacta atcaaggaag
     5101 aaagagtaat ttatttagat agtgatatta ttgttaacgg agatttgagc tcattatttg
     5161 aacttgattt tggagattac tctatagcag cagtaaggga tgcagacggt aatggtttta
     5221 actcaggggt gttggttatt gatagtcaaa agtggcgaga aaaggatgtt acttccatat
     5281 tgtttgataa gacagtggag tatatgtcat atcttgatca tactgacaca gataggttca
     5341 atggagatca aactattttc aatttagtct tccagaatca ttggctagag ttggataagc
     5401 gttttaatct tcaagttggt catgatgtaa ttgcttttta tagccactgg gattcacact
     5461 ttgagttgga tgaagaacct ttgatcatcc attatacgac ctatcgaaaa ccatggacta
     5521 ctctcatggg ctatcgctat cgagatttat ggtggtcttt tcacgatgtc acttttgacc
     5581 agatttctga ccattatcaa ggtcgtttcg ctgttaagag ggtttatgat tttcacgata
     5641 taaacctatt tacatttacg gattctcagg attttctgta tattgaagaa ctagcccaaa
     5701 ctcttcctaa tattggattc catatcggtg cctatacaga tatgggtgat attcttctgg
     5761 ctttggacaa atatcctaat gtttacttgt atcccagcat ggttggggca gtgattgatg
     5821 aaatgattga gaagtcagat gcttatcttg acattcataa agggagtcag atgaacttta
     5881 tcgtcaatcg ttatacgagt gcagacagac cagtattgac ttttgatgtg actaataaaa
     5941 atcaattgga acaaatagtt atttcctctc agtcaccaca gccaatgata gaagcaatta
     6001 aagagttaaa gaaagataaa atggacatga aggcaattgt actaggagcc aactaccaat
     6061 atgcagataa ggtattaact acaatcaaat cgatttgttg ccacaatcga ggtcttcgtt
     6121 tttatctgat taacagcgat tttccgacag aatggtttta taatctcaat cgtaagttaa
     6181 aggaactaga ctgtgaaatt gtcaacgccc gtgttaatag ctcccatatc agccaatata
     6241 agacaaatat tcactataca acatttttac gttattttat atcggatttt gtcgaggagg
     6301 ataaggtttt atacttggac tgtgatttgg ttgtcacaag agatttaagc cctctctttg
     6361 atgttgaatt aggagattat cctctggcag cagtcaaaga tttgggagcg caggtttact
     6421 ttaatgagca tggctttaac gcaggtgtct tgttaatcaa taatcgcctt tggaaacaag
     6481 aagaagttcg caaacagttg attgaaatga ctaatgagtt gcatgacaag gttgcccaag
     6541 atgatcaaag tatcttgaat ctcttattta aagatcgttg gttagtttta gactttaaat
     6601 ataactgtat taccttgcac acacatttct cagattatcg accagagtct ggtacttatc
     6661 caccgattat tcattatctg accgagagaa aaccatgggg attgtatgaa cgctccatct
     6721 atcgagatgt ttggtggtat tataatgccc aagattggtc tgatatagga gaagcaactc
     6781 cttgtctgac aaaagatcag gtgagtcaat acacaggagt ccaacactca ggagtccaac
     6841 actcagcttt tatttatacc ttctcatgtg atttgagaaa tatagaatgt ttgattgaag
     6901 gtttaccgaa tgtcaagttt tacatagctg ctcctgtgat ggtggcagat agtattacag
     6961 atctactagc ctacccaaat gtctctgtct tatcagatat tgcaggacaa ccacctttga
     7021 ttgatagctt agttgaaggc tgtgacttct tactggatat caatgctgat attgaagttg
     7081 atggaattat tgagcgtttt cgccaagcag gaaaaccagt atttgctttt gaaagtgtgg
     7141 tccatggaga acaaggtcag ttcctttatg accaagcgca tcctgaggag atggttcttg
     7201 ctattgaagc ctattgtcaa aatggagaat tgcctgtaaa aaagcttaaa tcctatccaa
     7261 aggtactgga tatccagcag agtcttgatt atatactaga acaccatttt tctgttattc
     7321 gctatgggga tggagaaatg gatattatga tgggacatgg gattccttat caagactatg
     7381 atgagaatct ggcagaacag cttagaagta tgatccaact agaaagctct ccagaattgc
     7441 tggtttgtct ctctgatgtt tttgaaggtt tggaacgcta caatcccgaa gctgtcaact
     7501 tttggcaaga gcatttagag cattataaag aagcctatca tagattttgt acagcaagtt
     7561 tctatggttc gacttttata tctcgtcctt atatggatct caaagataag actgcttcag
     7621 tagctcactt tgaaaaatta aagcaacttt gggatgaacg agatatcttg attgtcgaag
     7681 gtgaaaattc acgttcagga gttggtaatg acctttttga caacgctcgg tcagttgagc
     7741 ggattatttg cccttcgaga aatgcctacg gtaaagttca ggttattcaa gaagcagttg
     7801 agaagtacgc tgatgggaaa ttagtgtttt tgatgcttgg tcctacagcc aaggttttag
     7861 cttatcattt aagccagaaa ggcatacagg cgattgattt aggtcatgtt gattctgaat
     7921 atgagtggtt taaaatggga gcaacttcca aagtgaaatt ctcacacaaa catacagcag
     7981 agcataattt tgatcaagaa attcagttcg ttgaggatga aatttataat aagcaagtag
     8041 tcgtaaggat ttaaatagga ttatgaagat aaacattaca aatatttacg gtatgtctgg
     8101 tcaaagtaca gccttaatcg cccagaatga aaccgttaaa attgcaaaaa aattagactt
     8161 tcatgaactg agcttttatt tttacaatat ttatagcgat agtgaaggag agttgaacag
     8221 tcgcttagat ggtgttttgg ctaagttggg atatggagat attgttgttt atcaatctcc
     8281 tacctggaat ggtagggagt acgaccaaaa ttttattaga aaatgtaaga ttttaaacac
     8341 gaaaatgatt acctttattc atgacgtacc accccttatg tttccatcta attattactt
     8401 gatgcctgag tatattgaaa tgtacaatca atcggatcta gtagttgttc cctcggaaaa
     8461 aatgaaggaa cgtttgattc aggagggatt gacagttcaa aagattatta tccaaggaat
     8521 gtgggatcat gttcataact acccattgaa acaaccatct tttcagaaaa aattatattt
     8581 tgcgggtagt gtggaacgct ttgaacattt atccaactgg gcttactcaa cccctcttga
     8641 tattttttca gaatctaatt acgaaaatag taatccaaga gtttccttta aaggttggaa
     8701 aacagatcca gagttgcttt ttgctttatc agagggtggt tttggcttag tatgggggac
     8761 tagcgaaaat ccagctgatg aggaggacta ctatagattg aatatctctc ataaagttag
     8821 tacctatctt gctgccggaa ttccagtcgt ggttccttct tatctatcta acgccagttt
     8881 cataaaagaa aaaggcctag gttatgtggt ggatagtttg gaggaagcca atcgtcttgt
     8941 agaagaaacc acagcagaat tttatcaaca gatggtgaaa aatgtatcca aagtaagcta
     9001 cgctttgaaa gaaggttatt ttacaaaaaa attattgatt gatgcagtaa tgcaactatt
     9061 ggatatatag agtaagagat gatttaggaa aaatgatttt gaattagaaa cttgatttat
     9121 agattctttt attagaatca gcatgattta tcattttaat aaaagtagga gagaaacttg
     9181 aagaaaaaat tgaaatcagt cgtcgtgaaa cgagtcatgt ggacgatttg tttcatattt
     9241 gtatatatat tagggagtag actaacccta ccgtttgtaa atgtaaatga cacgagtttt
     9301 ttaggtggta atgcagcgtt tttggctttt tctactgcta tgacaggtgg aaatcttcgg
     9361 agtctttcac tattttcagt tggtctatct ccgtggatgt cagcaatgat tttatggcag
     9421 atgtttagta tgtctaagaa gcttggttta ggaaatttac cgcttgaaat ccaagaacgt
     9481 aggaaaatga tccttacctt tatcatctct tttattcaga cattagcaat tacattgaac
     9541 ctccccattc aagaaggggt taatcatgat ttagtcttaa tattaaacat tctacttttg
     9601 atatcaggaa ccttcttttt agtttggcta tcagatctta attctctttt aggagtagga
     9661 ggatctgttg tgattctgat gtcgagtatg atagtgagtg ttcctgaaaa tatagtaaga
     9721 agtataatag atttacatgt gaatttacta tttattatca gtttattact aatatcgatt
     9781 gcatttttat atatagcggt tcgtgttcaa aaagctcgat atcgtatttt ggtcaataaa
     9841 attatgatcc ataatcgttt caaacgttac tcttactttg atattatgtt aaatccagca
     9901 ggtgggatgc cctttatgta tgcgatatcg ctggtttcta ttcctcagta tttattgatg
     9961 ttgcttcata ttttcgtacc aaaaacaaga tgggtggaca attggatagc tgaatttacg
    10021 atagggcgac cagtatgggt gtatacatat attattgttc tatttttatt agggattgca
    10081 ttcgcatttg ttaatatgaa tggtgaacag attgctgata aaatgaaaaa atccggagaa
    10141 tatatttatg atatttatcc aggagaggat acagccttat acattaatag gttagtgtta
    10201 cgatttgctg tcattggttc tatttatatc ttgctgatgg caggaattcc aatgttaatc
    10261 attctgtatg aaccacgtta catgcaatta agtatgttac cgggcttatt tttgatgttt
    10321 aatggaatga tttttaacgt caaagaagaa ataaatgcat taacattgaa tgaaagctat
    10381 cgtcctcttg tagagagaaa atagttctcc tgtgaaacaa tttgtagaat attttaatat
    10441 aaatgtacct aaattatatt ctgatatttt atttaaaagc aatgcagata tattgaattt
    10501 aaatttgcag gatgtctaat actcaatgga aatcacagag aatcctagga agctagcaac
    10561 aggtggcaca aagaaggact ttgaaggtgc agataatact tgctgaggtt agctattact
    10621 ttatgttaag acaacgctga tgctacttta agagattttt gaagaacata gtaatatttt
    10681 ttaggaggag ctatgtatta ttttattcca tttttagaaa gtatgaatca atcttggcag
    10741 gtggatattg ttccttggta tcaaacgacc catcgtttgg agttcgatga tgttttgcat
    10801 caaatcagaa tttttaaaag ggaaggaata aagtctaaaa ttgtgttact accctatcat
    10861 ccacatatgc gctatctttt acatcgtcaa gatttattgg aagttgaagc attctctgtt
    10921 tttgatgcta ttcaggatat tgaaaacgaa gaaatctatc ccttacaact gaaagattta
    10981 gcatgggatg aagattgtga ctttatttat actccctttt taattgcagt aaaacagaaa
    11041 ggggagttgc atgcacatat agaatttgga acggaaggtt ttatcagtta tataacctat
    11101 tttaaagata atcaggtcga ttttatttgt tattttgatg atcgaggctt tttatctagt
    11161 cttgtgaaat atcaagataa tcaggcagta agtcgttatt attacaattc aaatgctgaa
    11221 tggcagatta aagaatattt gcaagggatt catacgaaag tggaggttaa cccccgtttc
    11281 agtcatcgct ttcggaaatc aacttatcaa agcgtggatg aagttgtttg ggaatttttt
    11341 gaaaaatttt taacagcaga gtacaaagag ggagaatcat ttgttcttgc agctcaaact
    11401 aagtatcaga atcaattatt aaaacactta ccagagcatg ctgataaaat tttgactttt
    11461 tttattgagc gaaatcaaga agatgatttg aatcttcatc atcaagcagt aaaacaagct
    11521 aagattctaa tcagtgatcg ccaagatttt ttagaaagat taaaacagca ctatcctcaa
    11581 tttacctata aaatgcacca tttaccatct tttgatacac gtttaaaatt aggagtcagt
    11641 cagagagtaa aagagtcaaa attatatgtc caactagact taaatactcc ttttaattca
    11701 gaagcattat atgaagtctt aaactttgtt tctcaaaatc cattgactga aattgtcttt
    11761 gcaacattta atgcagaggg ttatcaaatt gaggcattac agaaacatct atttactctg
    11821 atttctgaac gtttaaactt tagagatttg ctaaaagaat cgattatctc aggagcggaa
    11881 aataaattag aagaaaataa ggaagagaat tatcgttttc aaattgtaaa tttaaatgat
    11941 gagataggtt tgattcgtga gttagagtat actcgtttaa ttgttgattt aaatcctatt
    12001 gcaaatatct atactcagat tgcagggatt agtgcaggaa tacctcaaat caatctatcc
    12061 gagtcggaat atgtgactca tttacaaaat gggtatattt tatcagattt atcagaattt
    12121 agtaaagctg ggcactattt cttagatact ctggaacatt ggaatcaagc tctaatccat
    12181 tctattgata agattcgaca aaatacaggg aatcagtttg ttcagaagtg ggaaagatgg
    12241 ctagaggagg cgaaaagtga gcaataaatt acatatattg caaataggga atcggaattg
    12301 gagtcattat tatgagatac ctgaaaatat agagtggcat tttttttggc ctggttcgac
    12361 aactgccata aagaaagtta tgaaaatgga agggatacga acattctcag gagtagtgat
    12421 tgaaaatcca gattatttac cagatttact tcctttaata aacatcttga ctccttatac
    12481 tatattctat tcagatatct gtgcatcgta ttctccattg gttgaggagt ttttgaagaa
    12541 aacatgcgca caggtcactg atttttccaa tccaagagaa ttattacgga ttttatctaa
    12601 ggctttattt aaaggtcagt atggagataa gttgactccg atagatatgg ttgtgaatcc
    12661 atattttgca ggtagtattc gttacaacgg atatgaaaat ttagaactcg ttgggagcta
    12721 tggtgaggat tttagaccac taattagttg gaagtacaat attcgagcaa gtgaatggaa
    12781 tccaattgaa ttgtggttgg aatatgagaa agacttatct tgtgatattc gaattgttgt
    12841 tagaaatatt caagatggtt ctacagctga ttttatcaaa gaacgaattt ttacaacaga
    12901 tgatatggaa gcagctatac tgctagatga tgatttttca tcttttatca gtgtatcatt
    12961 ggaagctaag ggaaacggga gattgaagat aggagcgctt catcagcgtt taacacggta
    13021 tcagtttggt aaatttgtgc tgggtgggaa tattatacgc agtaaaaata gagaagaaat
    13081 taactacttc ttttatccgg gtgattttaa acctccacta aatgtatatt tttctggata
    13141 tcgtcgagca gaaggatttg aggggtttgg aatgatgaaa tcattgggtt ctccttttct
    13201 tcttttccaa gatccgcgaa ttgatggtgg ggccttctat ttgggtgatg atgattttga
    13261 aaatgctgtt cgcagagtga ttcaacatca tttagatttg ttaggatttt ccaataaaga
    13321 gttaatttta tcgggaatat ctatgggaac ttatggtgct ttatattaca gttcggactt
    13381 tgaaccgaag gctgtaattg tgtcaaaacc tttgacgaat ttgggcttga ttgctgaaag
    13441 aggacgactt gaggcaccgg gattatttcc aactgctttt gatattttac gtcaccattc
    13501 ccaaggaaag gctgatatag attctataaa tattttaaat gctcgttttt gggaacgatt
    13561 tagaggggca gattttaatc aaacaatttt tggattatca tatatgaaag aggaagatta
    13621 cgatccgatt gcatatgata gtttagttga ctcgctttat agtacaggtg ctcgaattat
    13681 ggtaaaaggt acttctggtc gccataacga tgataacgat tcaactattt tatggtttgt
    13741 aaatttttat aaaatggttt tggagcaaga gtttgggaga aagtattgat ggtcataaga
    13801 cggcagaaag aaattttttg gggagaattt aagggagcta gtttaggtaa tttaagagaa
    13861 aatagctttc tctatggttc gattgttatt tattacgctc gtaatcacat ttattttgaa
    13921 aatgaaatga ttagttcagg gacaatggta catgaatgga cttctagttt caattttcaa
    13981 gggaatcgtt taactcccac cttacctctg ataaaaaaag gtcatcgtta tcgtttaaca
    14041 agtaatatga cgattaaacc tgataatggt ttatatttta gacttatttt taaagatcga
    14101 tatgacgaga aggtaagcca actgattaag aaagatttaa cttttacttt tacttatcca
    14161 gaagaagctt ataactatag catacagttg ttaagtgcag gtttaaaatc agttgatttt
    14221 cattcatttt caatagaaga ggattatact gaacaaaatg tggaataaga atagacaatt
    14281 acgcaaagta aaaaagatat tgaatcaaat taatcgaaga aaagaggaga tggccctact
    14341 gacagatgaa gaattagcag ctaagacgca agaatttaaa agaaggctga ctgcgggaga
    14401 aaccctagat gatattttgg ttgaggcttt cgctgttgtc cgagaggctg acaaacgaat
    14461 tctagggatg tttccttatg atgttcaagt catgggtgga attgtaattc atcaaggaaa
    14521 tgtagctgag atgaatactg gtgaagggaa aacattgact gctaccttac ctatttatct
    14581 caatgcttta tcaggacaag gtgtgattct tgtgacaact aattcttatc ttgctaaacg
    14641 tgatgcagag gaaatgggaa aggtttatga atttttagga ttaactattc gattaccctt
    14701 tgctgatgat gaggaagaaa aaattacacc taaagagaaa aaagaaatat atagtgcaga
    14761 tattgtgtat acaaccaata gtggattagg ttttgattac ctgattgata atctagcgtc
    14821 aagtgaagaa caaaagtaca tgcctgaatt taattttgtt ttagttgatg agattgattc
    14881 ggtgttgcta gacagtgctc agactccact tgtcatttcg ggctcacctc gagtccaatc
    14941 taatttttat ggaattattg atactttgat gacaactcta gtagatgggg aagattatat
    15001 atttaaggaa gaaaaaaagg aagtctggct aactaataaa ggtgccaaga ttgcagaaaa
    15061 atttcttgga attgacaatc tttatgctga agaaaataat gtattggcta gacatttggt
    15121 ctttgctttg cgagctcata ctctatttaa aagggataag gattatatta tccgtaaagg
    15181 ggaaaaggac caggaactag ttctgttgga tcaaggaaca gggcgtctaa tggaaatgac
    15241 taaacttcaa ggaggtctcc atcaggctat tgaagccaag gaacatgtca aattatctcc
    15301 tgagacgcgg gctatggcct cgatcaccta tcagagtctt tttaagatgt ttaataagat
    15361 atctggtatg acagggacag gtaaggtcgc ggaaaaagag tttattgaaa cttacaatat
    15421 gtctgtagta cgcattccaa ccaatcgtcc gagacaacgg attgactatc cagataatct
    15481 atatatcact ttacctgaaa aagtgtatgc atccttggag tacatcaagg aataccatgc
    15541 taagggaaat cctttactcg tttttgtagg ctcagttgaa atgtctcaac tctattcgtc
    15601 tctcttgttt cgtgaaggga ttgcccataa tgtcctaaat gctaataatg cggcgcgtga
    15661 ggctcagatt atctccgagt caggtcagat gggggctgtg acagtggcta cctctatggc
    15721 aggacgtggt acggatatca agcttggtaa aggagtcgca gagcttgggg gcttgattgt
    15781 tattgggact gagcggatgg aaagtcagcg gatcgaccta caaattcgtg gccgttctgg
    15841 tcgtcaggga gatcctggta tgagtaaatt ttttgtatcc ttagaggatg atgttatcaa
    15901 gaaatttggt ccatcttggg tgcataaaaa gtacaaagac tatcaggttc aagatatgac
    15961 tcaaccggaa gtattgaaag gtcgtaaata ccggaaacta gtcgaaaagg ctcagcatgc
    16021 cagtgatagt gctggacgtt cagcacgtcg tcagactctg gagtatgctg aaagtatgaa
    16081 tatacaacgg gatatagtct ataaagagag aaatcgtcta atagatggtt ctcgtgactt
    16141 agaggatgtt gttgtggata tcattgagag atatacagaa gaggtagcgg ctgatcacta
    16201 tgctagtcgt gaattattgt ttcactttat tgtgaccaat attagttttc atgttaaaga
    16261 ggttccagat tatatagatg taactgacaa aactgcagtt cgtagcttta tgaagcaggt
    16321 gattgataaa gaactttctg aaaagaaaga attacttaat caacatgact tatatgaaca
    16381 gtttttacga ctttcactgc ttaaagccat tgatgacaac tgggtagagc aggtagacta
    16441 tctacaacag ctatccatgg ctatcggtgg tcaatctgct agtcagaaaa atccaatcgt
    16501 agagtactat caagaagcct acgcgggctt tgaagctatg aaagaacaaa tccgtgcgga
    16561 tatggtgcgt aatctcctga tggggctggt tgaggtcact ccaaaaggtg aaatcgtgac
    16621 tcattttcca taagaggaga aaatatgaca atttacaata taaatttagg aattggttgg
    16681 gctagtagcg gtgttgaata cgctcaagcc tatcgtgctg gtgtttttcg gaaattaaat
    16741 ctgtcctcta agtttatctt tacagatatg attttagccg ataatattca gcacttaaca
    16801 gccaatattg gttttgatga taatcaggtt atctgacttt ataatcattt cacagatatc
    16861 aaaattgcac ctactagcgt gacagtggat gatgtcttgg cttactttgg tggtgaagaa
    16921 agtcacagag aaaaaaatgg caaggtttta cgtgtattct tttttgacca agataagttt
    16981 gtaacctgtt atttggttga tgagaacaag gacttggttc aacatgccga gtatgttttt
    17041 aagggaaacc tgattcggaa ggattacttt tcttatacgc gttattgtag cgagtatttt
    17101 gctcccaagg acaatgttgc agtcttatac caacgaactt tttataatga agacgggact
    17161 ccagtctatg atatcttgat gaatcaaggg aaggaagaag tttatcattt caaggataag
    17221 attttctatg gaaagcaagc ttttgtgcgt gcctttatga aatctttgaa tttgaataag
    17281 tctgatttgg tcattctcga tagggagaca ggcattggtc aggttgtgtt tgaggaagca
    17341 cagacagcac atttagcggt agttgttcat gcggagcatt atagtgaaaa tgctacaaat
    17401 gaggactaca tcctttggaa taactattat gactatcagt ttaccaatgc agataaggtt
    17461 gacttcttta tcgtgtctac tgatagacaa aatgaagttc tacaagagca atttgccaaa
    17521 tatactcagc atcagccaaa gattgttacc attcctgtag gcagtattga ttccttgaca
    17581 gattcaagtc aagggcgcaa accattttca ttgattacgg cttcacgtct tgccaaagaa
    17641 aagcacattg attggcttgt gaaagctgtg attgaagctc ataaggagtt accggaacta
    17701 acctttgata tctatggtag tggtggagaa gattctctgc ttagagacat tattgcaaat
    17761 catcaggcag aggactatat ccaactcaag gggcatgcgg aactttcgca gatttatagc
    17821 cagtatgagg tctacttaac ggcttctacc agcgaaggat ttggtctgac cttgatggaa
    17881 gctattggtt caggtctacc tctaattggt tttgatgtgc cttatggtaa tcagaccttt
    17941 atagaggatg ggcaaaatgg ttatttgatt ccaagttcat ctgaccatgt agaagaccaa
    18001 atcaagcaag cttatgccgc taagatttgt caattgtatc aagaaaatcg tttggaagct
    18061 atgcgtgcct attcttacca aattgcagaa ggcttcttga ccaaagaaat tttagaaaag
    18121 tggaagaaaa cagtagagga ggtgctccat gattgaactt tatgatagtt acagtcaaga
    18181 aagtcgagat ttacatgaaa gtctagtcgc tactggtctt tctcaacttg gagtggtcat
    18241 cgatgcagat ggttttctgc ctgatggtct gctttctcct tttacctatt atctaggtta
    18301 cgaggatgga aaacctctct attttaacca agttcccgtt tcagattttt gggaaatttt
    18361 aggagataat cagtctgctt gtattgaaga tgtgacgcag gagagggctg ttattcatta
    18421 tgttgatgga atgcaggctc gcttggttaa acaggtagac tggaaagacc tagaaggtcg
    18481 agtacgtcag gttgaccact acaatcgctt tggtgcttgc tttgctaaaa ccacttatag
    18541 cgcagatagc gagccgatta tgacagttta ccaagatgtc aatggccaac aagttttact
    18601 ggaaaaccat gtgacgggtg atatcttatt gactttgcct ggtcagtcca tgcgttactt
    18661 tgcaaataaa gttgaattta tcaccttctt tttgcaagat ttggaaatag ataccagtca
    18721 gcttatcttt aatactctag cgactccttt cttggtttcc ttccatcatc cagataaatc
    18781 tggctcggat gtcttggtat ggcaggaacg tctctatgat gccattccag gtaatatgca
    18841 gttgattttg gaaagtgata atgtgcgtac taagaagatc atcattccaa ataaggcgac
    18901 ttatgagcgc gctttagagt taactgacga gaaataccat gatcagtttg tgcacttggg
    18961 ttatcattac cagttcaaac gtgataattt cctaagacga gatgccttaa tcttgaccaa
    19021 ttcagatcag attgagcaag tagaagcaat cgcaggagcc ttgcctgatg tcactttccg
    19081 tattgcagcg gtgacagaga tgtcttctaa gctcttagac atgcttcgct atcctaatgt
    19141 gttcctttac cagaacgcta gtccacagaa gattcaggag ctgtatcaac tgtcggatat
    19201 ttacttggat ataaaccaca gtaatgagtt gctacaggca gtgcgtcagg cctttgagca
    19261 caatctcttg attcttggct ttaatcagac ggtgcacaat agactttata tcgctccaga
    19321 ccatctattt gaaagtagtg aagttgctgc tttggttgag accattaaat tggccctttc
    19381 agatgttgat caaatgcgtc aggcacttgg caaacaaggc caacatgcaa attatgttga
    19441 cttggtgaga tatcaggaaa ccatgcaaac tgttttagga ggctaacatg tcagaggaag
    19501 atttatttta caaagacgtt gaaggccgca tggaagagtt gaaacaaaaa cccatcaaga
    19561 aggaaaaaga aacccgaggg gagaagatta gtaaaacttt ttcactttta ctgggcttaa
    19621 tgattctgat tggtttgctc tttactttgc tgggaatttt gaggtagatc tatgattgaa
    19681 atactaattg ttttagctat tatcctatct cttgctttga ttgtattggt aactatacaa
    19741 ccccgtcaaa atcaactatt ttccatggat gccactagta atattggtaa accaagctac
    19801 tggcagagca acaccttggt caaggtgctc actttattgg tgagtttggc tttatttgtt
    19861 ctactattaa tctttatggt gattacttat aaataaaaga aaacttcaga tattcacctt
    19921 ttgtggattg gtctgaagtt ttctttttta tactcaatga aaatcaaaga gcaaactagg
    19981 aagctagccg caggctgctc aaaacacagt tttgaggttg tagata
//
LOCUS       DAVMAH010000041        19952 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVMAH010000041 DAVMAH010000000
VERSION     DAVMAH010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.041"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            159..314
                     /locus_tag="VYO94_001459"
     CDS             159..314
                     /locus_tag="VYO94_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760085.1"
                     /translation="MEKLQFFLSQRACGCWKQAEKAVKLGSSETREENIILKGVPFIA
                     QPVTGDI"
     gene            449..1810
                     /gene="trpE"
                     /locus_tag="VYO94_001460"
     CDS             449..1810
                     /gene="trpE"
                     /locus_tag="VYO94_001460"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV1760086.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKSHIAPKKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVINPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            1807..2373
                     /locus_tag="VYO94_001461"
     CDS             1807..2373
                     /locus_tag="VYO94_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV1760087.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGHAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            2384..3388
                     /gene="trpD"
                     /locus_tag="VYO94_001462"
     CDS             2384..3388
                     /gene="trpD"
                     /locus_tag="VYO94_001462"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV1760088.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            3385..4152
                     /gene="trpC"
                     /locus_tag="VYO94_001463"
     CDS             3385..4152
                     /gene="trpC"
                     /locus_tag="VYO94_001463"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV1760089.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            4139..4738
                     /locus_tag="VYO94_001464"
     CDS             4139..4738
                     /locus_tag="VYO94_001464"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV1760090.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGEGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLPQSFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            4716..5939
                     /gene="trpB"
                     /locus_tag="VYO94_001465"
     CDS             4716..5939
                     /gene="trpB"
                     /locus_tag="VYO94_001465"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV1760091.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            5932..6708
                     /locus_tag="VYO94_001466"
     CDS             5932..6708
                     /locus_tag="VYO94_001466"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV1760092.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDITLIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(6680..6790)
                     /locus_tag="VYO94_001467"
                     /pseudo
     CDS             complement(6680..6790)
                     /locus_tag="VYO94_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(6979..8325)
                     /locus_tag="VYO94_001468"
     CDS             complement(6979..8325)
                     /locus_tag="VYO94_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEV1760093.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRKKASLMMH"
     gene            complement(8590..10221)
                     /locus_tag="VYO94_001469"
     CDS             complement(8590..10221)
                     /locus_tag="VYO94_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV1760094.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            10514..15493
                     /locus_tag="VYO94_001470"
                     /pseudo
     CDS             10514..15493
                     /locus_tag="VYO94_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
     gene            15583..16779
                     /locus_tag="VYO94_001471"
     CDS             15583..16779
                     /locus_tag="VYO94_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV1760095.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            16915..17442
                     /locus_tag="VYO94_001472"
     CDS             16915..17442
                     /locus_tag="VYO94_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1760096.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            17519..17875
                     /gene="glnR"
                     /locus_tag="VYO94_001473"
     CDS             17519..17875
                     /gene="glnR"
                     /locus_tag="VYO94_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV1760097.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            17912..19258
                     /gene="glnA"
                     /locus_tag="VYO94_001474"
     CDS             17912..19258
                     /gene="glnA"
                     /locus_tag="VYO94_001474"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV1760098.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(19348..19467)
                     /locus_tag="VYO94_001475"
     CDS             complement(19348..19467)
                     /locus_tag="VYO94_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV1760099.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         6105 a         3817 c         4552 g         5478 t
ORIGIN      
        1 aaccaatacc tacggcaagg cgacgttgac gcggtttgaa gagattttcg aagagtataa
       61 aggtgtaccg agatgaacat ctcttcatca atgtctctgg tcgtggaggc aaggacctag
      121 ctgcgattgc agactaccta gaagctaaaa aataatagat ggaaaaatta cagttctttc
      181 tctcacagag agcttgtggt tgctggaaac aagcagagaa agctgtaaag ttgggttcat
      241 ctgaaacgag agaagaaaac atcattctca agggagtgcc ctttatcgca cagcctgtta
      301 caggagatat ctgagacagg aatgagagat aggagaaatc ctataattga ggtggcaccg
      361 cgaatttcgt cctcacgcaa gttattttgc gtggggattt ttcatacagt cgctacgaac
      421 tagaattaga actgaaaggg aaattacaat ggaacgaatc attcatggag atgtcttatc
      481 accaatcttg gcttatatgc gcttaaaggg gcaacacaag gttatcttag agagtattcc
      541 gagagacaag gaaacagctc gtttttctat cctagcctat aatcctgttt ttgagattaa
      601 gtttgaaaat ggagttcttt atcaaaatgg tcaagtgatt gatcgggatc ccttggattt
      661 cctttatgaa gtgattcata agagtcagca ccattcagag ctaccttttg gtggtggagc
      721 cattggtttt gtgggttacg atatgatttc gctttatgaa gaaattggtc aaatccctga
      781 ggatacaatt gggacgccag acatgcattt ctttgtctat gagagctata tggtctttga
      841 ccacaagaag gagaagatac atgtcataga ggatgcactt tatagtgagc gcagtcaaga
      901 agccttggaa aaatccttga accaagtgct tgaggaatta cgcattcctg ctccaaatga
      961 atttgaagac ttggatctat ctccgttaga cttcaaatcc catatcgctc ctaagaagtt
     1021 tgaggaaatg gtggaaaccg ctcgcgactt gattcgtaat ggcgatatgt tccaatgtgt
     1081 actcagccag cgtttctcag cagaagttac tggaaatcca tttgacttct acagaaatct
     1141 ccgcgtgatc aatccatcca attacctcta tttctatgat tttggggatt atcaaatcat
     1201 cggagccagt ccagaaagtt tggtttctgt caaaaatggc atcgtgacaa ccaatccgat
     1261 tgcagggacg cgaccaagag gggctacgga tgaagaagac aaggccttgg cgactgacct
     1321 cctctctgat gagaaggaaa cagcagaaca tcgaatgttg gtagacctgg gtcgtaatga
     1381 tattggtcgc atctctgaaa cgaccagtgt ccaagtcact aagtatatgg aagtggagct
     1441 cttccgttat gttatgcatc tgaccagcgt ggtcaagggg cgtttgcttg cagaactcac
     1501 tgccatggat gccttgaaag ctacacttcc tgctggaacc gtttctggag caccaaagat
     1561 tcgagcgatg agacgtatct atgaactgga aacggaaaaa cggggagtat acgctggggc
     1621 aatcggctac ttgtctgcga cgggtgatat ggatttggcc atcgccatcc gaaccatgat
     1681 tctcaaaaat caaagagcct atgtgcaggc tggggcaggg attgtctacg actctatcgc
     1741 ccaaaacgaa taccaagaaa ccattaacaa agcaaaatct atgactagaa ttggagaact
     1801 aagaccatga ttttattgat tgacaactat gattctttta cctataactt ggcccaatac
     1861 attgggaatt ttgcagaagt tcaggttctg agaaatgatg attccaagct gtatgaagaa
     1921 gctgaaaaag cagatggtct ggtcttttct cctggtcctg gttggccagt tgatgctgga
     1981 aagatggaag acatgatttg tgattttgca ggcaagaagc cgattctagg gatttgtttg
     2041 ggtcaccaag ccattgcaga agtctttggt ggtaagctag gtttggctcc aaaagtcatg
     2101 catgggaaac agagcaatat caactttgaa gcgccatctg ttttgtatca aggtattgag
     2161 gatggacatg cggtcatgcg ttatcacagt attttgattg aggaaatgcc agaagacttt
     2221 gaagtgacag ctcgttcgac tgatgaccaa gccatcatgg ggattcaaca taaaaaccta
     2281 ccgatttatg gcttccagta ccatccagag agcattggaa cgccagacgg cttgtcttct
     2341 attcggaatt ttatcgagga ggttgtaaag tgaggaaact aggatgaaag agattattga
     2401 aaaactagca aaatttgaaa atttatcagg tgtggaaatg acggatgtca ttgagcgtat
     2461 cgtaactggg cgtgtaactg aagcgcagat tgcttctctc ctcttagctc ttaagatgaa
     2521 gggggaaaca cctgaagaac gtacagccat tgcccaagtc atgagaggac atgcccagca
     2581 tattccaact gagattcatg atgctatgga caactgtggt acaggtgggg acaagtcttt
     2641 cagttttaat atttccacaa ctgcagcctt tgtcttggct ggtggcggta ttcacatggc
     2701 caagcatggt aaccgctcga tttcttctaa atctggttcc gcagatgtcc tcgaagcctt
     2761 gggaatcaat cttgacctca aaccagctga actaggtaag gtctttgata aaactggaat
     2821 cgtctttctc ttcgctaaaa atatgcaccc agctatgaaa tacatcatgc cagctcgttt
     2881 ggaattggga attccaacga ttatgaactt gactggtcca ctgattcatc caatggcttt
     2941 agaaacacag cttcttggaa ttagtcgtcc agaactccta gaaagtacag ctcaggtttt
     3001 gaaaaatatg ggtcgcaaac gtgccatcgt ggttgctgga ccagaagggt tggatgaagc
     3061 tggcttgaac ggaacaacca agattgcact tcttgaaaat ggcgaaatca gcttgtcaag
     3121 ctttactcca gaggatttgg gaatggaaga ctatgctatg gaagatattc gtggtgggaa
     3181 tgctcaggaa aatgcagaaa ttttgcttag cgttctgaaa aacgaagcaa gtccattctt
     3241 ggaaacgaca gtcttgaatg ctggtcttgg tttctatgct aatggtaaga ttgatagcat
     3301 caaggaagga gttgccttgg cccgtcaagt gattgctaga ggcaaggccc ttgaaaaact
     3361 cagactgtta caggagtacc aaaaatgagt caggaatttt tagcacgaat cttagagcag
     3421 aaggcgcgtg aggtggagca gatgaagctg gagcaaatcc agcctctgcg ccagacctat
     3481 cgcttggcag aatttttgaa gaatcatcag gaccgcttgc aggtaatcgc tgaggtcaag
     3541 aaagctagcc ctagtttggg agatatcaat ctcgatgtgg atattgtgca acaggcccag
     3601 acttatgaag aaaacggagc agtgatgatt tcggtgttga cagatgaggt tttctttaaa
     3661 gggcatttgg attatctacg ggaaatttcc agtcaggtag agattccgac gctcaacaaa
     3721 gactttatca tagatgaaaa gcaaatcatc cgcgctcgca atgcaggtgc gacagttatc
     3781 ttgctcattg tggcagcctt gtccgaagaa cgcctcaagg aactgtatga ctacgcgaca
     3841 gagcttggtc tggaagtctt agtggagact cacaatctag ctgaactaga ggtagcccac
     3901 agacttggtg ctgagattat cggggtcaac aaccgcaact tgactacctt tgaggtcgac
     3961 ttgcagacca gtgtagattt agccccttac tttgaggaag gtcgctatta catttctgaa
     4021 tctgccattt tcacagggca ggatgcggaa cgactagccc catactttaa cggaattttg
     4081 gtagggacag ctcttatgca ggcagaaaat gtggcccaga gaatcaagga gttgcagatt
     4141 gacaaaggtt aaaatttgtg gactatcgac caaagaagcg gtggaaacag ccgtttcagc
     4201 aggagccgac tatatcggtt ttgtctttgc acctagtaaa agacaggtga ctttagaaga
     4261 ggcagctgag ttggcaaagc ttattcctgc agatgtgaaa aaggttggag tatttgtttc
     4321 accaagtcgg gtagaactgc tggaagcgat tgacaaagtt ggcttggact tggttcaagt
     4381 tcacggtcag gtggcagatg atttatttga gaatttgcct tgtgctagca ttcaggctgt
     4441 gcaggtagat ggagagggtc atgtgcccaa ttctcaggca gactatctac tctttgatgc
     4501 ccctgtggct gggagtggcc agccctttga ttggggtcaa ctggatacga ctggattacc
     4561 tcagtctttc tttatcgcag gtgggcttaa tgaagacaat gtagtaaaag caattcaaca
     4621 ctttactccc tatgcagtag atgtatcaag cggagtggag acagatggac aaaaagatca
     4681 tgaaaagatt agaagattta tagagagggt aaagaatggc atatcaagaa ccaaataaag
     4741 atggatttta cggaaaattc ggcggacgtt ttgtcccaga aacattgatg acagcagttt
     4801 tggagttgga gaaggcctac cgtgaaagtc aggcagaccc aagtttccaa gaggaattaa
     4861 accaactttt gcgccagtat gtgggacgtg aaactcccct ttactacgca aaaaacttga
     4921 cccagcatat cggcggagcc aagatttatc tcaaacggga agaccttaac catacaggag
     4981 cccacaagat taacaatgcc ttaggacaag tttggcttgc caaacgcatg ggtaaaaaga
     5041 aaattatcgc agaaactggt gctggtcagc acggtgtggc aactgcaact gctgcggccc
     5101 tctttaacat ggaatgtacc atctacatgg gtgaggaaga tgtcaaacgc caagccctca
     5161 atgtcttccg tatggagctt ttgggagcta aggtcgaggc cgtgacagat ggttcgcgcg
     5221 tgctcaagga tgcggtcaat gcagctcttc gttcatgggt ggctaatata gatgataccc
     5281 actatatcct tggttctgcc ttggggcctc atccatttcc agaaattgtt cgtgacttcc
     5341 aaagtgtcat tggtcgagag gctaaacaac agtaccgtga cttgacagga caaaatctgc
     5401 cagatgccct agtagcctgt gttggtggtg ggtcgaatgc catcggtctc ttccatccct
     5461 ttgtagaaga tgagtcagta gccatgtatg gagctgaagc ggctggactt ggtgtggata
     5521 cggagcacca cgcagctacc ttgaccaagg gtcgtccagg tgtccttcac ggttccctca
     5581 tggatgtgct ccaagatgcc catggtcaaa ttcttgaagc cttctctatc tcagcaggtt
     5641 tggactatcc tggtatcggt ccagagcatt ctcactacca cgatattaaa cgtgccagct
     5701 atgtccctgt gacagacgaa gaagccttgg aaggattcca actcttgtct cgtgtggaag
     5761 ggattatccc agccttggaa tctagccatg ctatcgcctt tgcggtgaaa ttggccaaag
     5821 aacttggacc agaaaagtct atgattgtct gcctatcagg tcgtggggac aaggatgtgg
     5881 ttcaagtcaa agaccgcttg gaagcagatg cagcaaagaa gggagaagct catgcctaag
     5941 acactaacag aaaaattgaa tgctattaaa gcagctggaa aaggaatttt tgttccctat
     6001 atcatggctg gtgaccacga gaaaggtttg gacggtcttg ctgaaacaat tcacttttta
     6061 gaagatttgg gtgtctctgc aattgaagtg ggtattccct tttcagaccc tgttgcagat
     6121 ggacctgtta tcgaagaagc tggcttgcgc agtttagccc acgggacctc tacccaggct
     6181 ttagttgaaa ccttgaaaac cattgaaaca gagattccac tggtcatcat gacctacttc
     6241 aaccccctct ttcagtacgg tgtggagaac tttgtcaaag atctggctga tacagctgtg
     6301 aagggcttga ttatcccaga cttgcctcat gaacatgcca actttgtaga accatttttg
     6361 gcagatacag atatcacctt gattccttta gtaagcttga ccacaggaat tgagcgccag
     6421 aaagagttga ttgaaggggc ggagggattc gtctatgccg ttgccatcaa tggagtgaca
     6481 gggaaatcag gcaattaccg tgcagatttg gacaagcact tggcgcaact tcatcaagtg
     6541 gccgacatcc cagtcttgac aggttttggt gtatctagtc aagccgatct ggaacgcttc
     6601 aatgcggtgt cagatggtgt tatcgtcggt tcaaaaatag taaaagctct ccaccaagga
     6661 gagccgattc aggattttat cagacaagca gtagcttacc aaaaataatc aaacaagtag
     6721 caagtaagag gaaaggcacg aaaggaagtc tttccttttt cttttgcagg agaaaggcta
     6781 gttttatccc aaatcattca tacctctctc aactagatgt aacttacaaa acccctgacc
     6841 tcatgagcca ctttcttcct cctcatgagg tcagttttac tttctgctgt tccagtatcg
     6901 tttttcctcg ctagatttcc tcaaaagggc agactcctcc cttggtgcgt cacacgattt
     6961 tttcatctca actgttcttt aatgcatcat taacgacgct ttttttctag gtggttcata
     7021 aggaacagga agattcaggt tgacttttct aatcctagaa taaagtgctg aaaacaattc
     7081 ggaataggca tagagactag acaatttgag gagctgcttg cgtcctgttc gaacacattt
     7141 tcccaccacg tgaagaaaaa gatggcggaa gcgtttgatt gttaaagttt ggaagtcacc
     7201 tccagctaga tgtttgagaa aaagatagag attgtaggcg atacagctca tcatcatacg
     7261 aacttcgttt ttgattaagg ttgaactatc cgttttatcg ccaaaaaatc cctccttcat
     7321 ctccttgatg aaattctcgg cttgaccacg tccacgataa agctgaaact ggtcttggct
     7381 tgttccactc gtcatatttg taacgagaga aataacatcg tagaacaagt ttccttcttt
     7441 tcgttcagag aactggcaga cacgacgctt gtgcgaccaa gatcctgctt gatagagagt
     7501 ttctgagtag gcggagtggg gcaagatggt taagtcctca tcctgtgggc aagggaggga
     7561 aaggtctcca agacggctca gaacagtatt tttcttgagt tttatgaggt agtattgccc
     7621 tgttttttca attaaatcgt ataattttgg ggtcgcaaag ccactatcca ttcgaaagag
     7681 aagttgatta aaccgttcta aaacaggtgt gataaagctg tctgcctctt cagaacaata
     7741 acgattacca ggacgaagct gggcattgaa acaataacct gtcttcccct cgaaagcata
     7801 aagaggatga tagccatgag cacgatagtg ggcgttataa gcaacacctt cttgcttgcc
     7861 ataagttgtg aaatgggtag aatcgatatc tacaatgagt tggtttagct ggtgaaactg
     7921 taaaaagaat tcgaccaatt caaggttgag gcatcgcaaa ctatggactg tttcctcgtc
     7981 agttctggaa agaaaacggg ataaggttgg ctgtgaagca agctgccctc cttccaacaa
     8041 ttttggaaag taggcatcag ctgacaattc tttacaagca tagtccgttc cataacctgt
     8101 taacagttga aagaggaact ggacaaggat atctgaatcc gaataacgac agtagcggcg
     8161 ttggtcattc gttactaaat acttagaaat ccgctctttt agtttcaact gggaaaaaag
     8221 ttcctgaaaa aagataagac caccatactg ggttaaatga cctccatcga aagatagttg
     8281 gtaaaaagac ttgttttgga agtgatgatt tggtaaactg ttcatgtgag tttcctttct
     8341 ttttgtgttt ttttctacac ttataccata aaggggaaac tcttttttgt ctagtaaaaa
     8401 acacccattg ggtgaaaaaa gaaaccatcc aggatctaag ctaaggcaag gattctggat
     8461 ggtttttaga tttggggtga ataattgggg actatatatc tgcagaatac tctttcagtt
     8521 tcattcatcc tagtcttgct taggaaaaag taaaaagcca tccaattatg atggatagct
     8581 tcttggttct tagatttgtt ctgcaaaaac cttttcagca aggttcatag cgtggtctga
     8641 tacacgagtg tagtgtgaga tgatgtcgat aaagttgacc ccagcttgtg ttgaacattc
     8701 gcctttgttg aggcgtttga tgtgggtttt tctgagaaca cgttctatct tattgattgc
     8761 ttcatgacgt tctacaagac tgcgtgcttt ttcaatatca ttgttttcca cactatccag
     8821 agcatctttg ataaagtcac tagtttggcg gtaaacttcc tctaattctt tcaaggcggc
     8881 atcagaaaat tcaacatttt tccgttgaag atagtcagtc agattgagta gagcctccgt
     8941 gtggtctcca atccgttcca aatcacggga ggaatcaagg atattggtaa gcacttcact
     9001 ttctttttgg ctgagagctt cgcttgaaag ggcaatgaga taacgtgtta attgctcatc
     9061 gatggtgtta attgcttctt cggttttatg ccctttttca gcaacttttt catccaagtc
     9121 aatgatgtac ttataggaaa ggtcaaaggc tttggcagcg tagtttccta agtgcaagag
     9181 ctctttctta gcatttccta gagcgataga tggggcctgt ttgatgaaat gttcatcaag
     9241 atataagggt tcgtatttga caacctcgtc ctctccagga ataatcttgg ttacaaagta
     9301 agccagagct ccgataaatg gaaattggac aatggtgttg gtaatattaa aggttccgtg
     9361 agcaaaggcg atggtcattt ccggtgctag atttagcgta gcttcaaacc aatgaatcag
     9421 gacagtaaaa ggaactagaa aaataacgca gacaactgtt ccgataacgt tgaaggcaac
     9481 atgagctcct gctacccgtt tagctgcaat attagcccct aaagaggcaa tgatggctgt
     9541 aatggttgtc ccgatattgt caccaaatag aactggcaaa gctccctgta gatcaattag
     9601 attgccggcg tagaggtttt gtaaaatccc aatggtagcc gaagaagctt gaattagcaa
     9661 ggtcaagcca gtaccgacaa agacacccaa aacaggattc ttacttagct caatcatata
     9721 gtccttaaag acctgtaaat ccttgagtgg agccattgcg ccgctcatga gattgagggc
     9781 aaaaaagata ccaccgacac caaagaggat gcgtccgata ttattgactg tccgattttt
     9841 cgtaaaaaaa agacagacgg caccgataaa gagcataggt agggcatagt tacctaattt
     9901 aaaaccgatg agaaaggatg tgacagttgt cccaatatta gcacccatga caatcccgat
     9961 agcctgacgt aaggttaaga gaccggcact gaccaggccg actgtgataa ctgttacacc
    10021 agaactagac tgaattagag cagtcatccc aataccaacc agaactccaa agaaaggatt
    10081 actagtatat ttgtcaatgt aaaaacgaag gcgatctcca gcagcttgtt gtaaaccgtc
    10141 tcccatggtc ttgatgctat ataagaatag ccccagacca cctaaaaagt gaaataaaat
    10201 ttcctgccaa ttaatggaca tttctttttc ctccgaaaaa taatcgcgga atatctccta
    10261 ttctatttta aaggataaaa gtaaatctaa caagtgttaa tgtcaagttt gtaaaagaaa
    10321 attataattg ataagtgtat tatttttaag agtttttaac cttattttag atttgtgcaa
    10381 acagttattg ttttttgtct aaaaatgttt taggataaaa atgtgattat catggttcta
    10441 gagtttgata aaaaactaca gaatataaag cgctttcttg aaaacaacaa aatcaatctt
    10501 ttaggaggag aaaatgaaga atccattttt tgaaagacgt tgtcgttaca gtattcgtaa
    10561 gttatcagta ggagcctgct cgctgatgat tggtgctgtt ttatttgctg gtccagcctt
    10621 ggctgaagaa actgcagttc ctgaaaatag cggagctaat acagagcttg tttcaggaga
    10681 gagtgagcat tcgaccaatg aagctgataa gcagaatgaa ggggaacatg ctagagaaaa
    10741 caagctagaa aaggcagaag gagtagcgat agcatctgaa actgcttcgc cagcaagcaa
    10801 tgaagctgca actactgaaa ctgcagaagc agctagcgca gctaaaccag aggaaaaagc
    10861 aagtgaggtg gttgcagaaa caccatctgc agaagcaaaa cctaagtctg acaaggaaac
    10921 agaagcaaag cccgaagcaa ctaaccaagg ggatgagtct aaaccagcag cagaagctaa
    10981 taagactgaa aaagaagtcc agccagatgt ccctaaaaat acagaaaaaa cattaaaacc
    11041 aaaggaaatc aaatttaatt cttgggaaga attgttaaaa tgggaaccag gtgctcgtga
    11101 agatgatgct attaaccgcg gatctgttgt cctcgcttca cgtcggacag gtcatttagt
    11161 caatgaaaaa gctagcaagg aagcaaaagt tcaagcctta tcaaacacca attctaaagc
    11221 aaaagaccat gcttctgttg gtggagaaga gttcaaggcc tatgcttttg actattggca
    11281 atatctagat tcaatggtct tctgggaagg tctcgtacca actcctgacg ttattgatgc
    11341 aggtcaccgt aacggggttc ctgtatacgg tacactcttc ttcaactggt ctaatagtat
    11401 tgcagatcaa gaaagatttg ctgaagcttt gaagcaagac gcagatggta gcttcccaat
    11461 tgcccgtaaa ttggtagaca tggccaagta ttatggctat gatggctatt tcatcaacca
    11521 agaaacaact ggagatttgg ttaaacctct tggagaaaag atgcgccagt ttatgctcta
    11581 tagcaaggaa tatgctgcta aggtaaacca tccaatcaag tattcttggt acgatgccat
    11641 gacctataac tatggacgtt accatcaaga tggtttggga gaatacaact accaattcat
    11701 gcaaccagaa ggagataagg ttccggcaga taacttcttt gctaacttta actgggataa
    11761 ggctaaaaat gattacacta ttgcaactgc caactggatt ggtcgtaatc cttatgatgt
    11821 atttgcaggt ttggaattgc aatagggtgg ttcctacaag acaaaggtta agtggaatga
    11881 cattttagac gaaaatggga aattgcgcct ttctcttggt ttatttgccc cagataccat
    11941 tacaagttta ggaaaaactg gtgaagatta tcataaaaat gaagatatct tctttacagg
    12001 ttatcaagga gaccctactg gacaaaaacc aggtgacaaa gattggtatg gtattgctaa
    12061 cctagttgcg gaccgtacgc cagcggtagg taatactttt actacttctt ttaatacagg
    12121 tcatggtaaa aaatggttcg tagatggtaa ggtttctaag gattctgagt ggaattatcg
    12181 ttcagtatca ggtgttcttc caacatggcg ctggtggcag acttcaacag gggaaaaact
    12241 tcgtgcagaa tatgatttta cagatgccta taatggcgga aattccctta aattctctgg
    12301 tgatgtagcc ggtaagacag atcaggatgt gagactttat tctactaagt tagaagtaac
    12361 tgagaagacc aaacttcgtg ttgcccacaa gggaggaaaa ggttctaaag tttatatggc
    12421 attctctaca actccagact acaaattcga tgatgcagat gcatggaaag agctaaccct
    12481 ttctgacaac tggacaaatg aagaatttga tctcagctca ctagcaggta aaaccatcta
    12541 tgcagtcaaa ctatttttcg agcatgaagg tgctgtaaaa gattatcagt tcaacctagg
    12601 acaattaact atctcggaca atcaccaaga gccacaatcg ccgacaagct tttctgtagt
    12661 gaaacaatct cttaaaaatg cccaagaagc ggaagcagtt gtgcaattta aaggcaacaa
    12721 ggatgcagat ttctatgaag tttatgaaaa agatggagac agctggaaat tactaactgg
    12781 ctcatcttct acaactattt atctaccaaa agttagccgc tcagcaagtg ctcagggtac
    12841 aactcaagaa ctgaaggttg tagcagtcgg taaaaatgga gttcgttcag aagctgcaac
    12901 cacaaccttt gattggggta tgactgtaaa agataccagc ctaccaaaac cactagctga
    12961 aaatatcgtt ccaggtgcaa cagttattga tagtactttc cctaagactg aaggtggaga
    13021 aggtattgaa ggtatgttga acggtaccat tactagcttg tcagataaat ggtcttcagc
    13081 tcagttgagt ggtagtgtgg atattcgttt gaccaagcca cgtaccgttg ttagatgggt
    13141 catggatcat gcaggagctg gtggtgagtc tgttaacgat ggcttgatga acactaaaga
    13201 ctttgacctt tattataaag atgcagatgg tgagtggaag ctagctaagg aagtccgtgg
    13261 taacaaagca cacgtgacag atatcactct tgataaacca atcactgctc aggactggcg
    13321 cttgaatgtt gtcacttctg acaatggaac tccatggaag gctattcgta tctataactg
    13381 gaaaatgtat gaaaagcttg atactgagag tgtcaatatt ccgatggcca aggctgcagc
    13441 ccgttctcta ggcaataaca aggtacaagt tggctttgca gatgtaccgg ctggagcaac
    13501 tattaccgtt tatgataatc caaattctca aactccgctc gcaaccttga agagcgaagt
    13561 tggaggagac ctagcaagtg caccattgga tttgacaaat caatctggtc ttctttatta
    13621 tcgtacccag ttgccaggca aggaaattag taatgtccta gcagtttccg ttccaaaaga
    13681 tgacagaaga atcaagtcag tcagcctaga aacaggacct aagaaaacaa gctacgccga
    13741 aggggaggat ttagacctta gaggtggtgt tcttcgagtt cagtatgaag gaggaactga
    13801 ggacgaactc attcgcctaa ctcacgcagg tgtatcagta tcaggttttg atacgcatca
    13861 taagggagaa cagaatctta ctctccaata tttgggacag ccagtaaatg ctaatttgtc
    13921 agtgactgtc actggccaag atgaagcaag tccgaaaact attttgggaa ttgaagtaag
    13981 tcaggaaccg aaaaaagatt acctagttgg tgatagctta gacttgtctg aaggacgctt
    14041 tgcagtggct tatagcaatg acaccatgga agaacattcc tttactgatg agggagttga
    14101 aatttctggt tacgatgctc aaaagactgg tcgtcaaacc ttgacgcttc gttaccaagg
    14161 tcatgaagtc aactttgatg ttttggtatc tccaaaagca gcattgaacg atgagtacct
    14221 caaacaaaaa ttagcagaag ttgaagctgc taagaacaag gtggtctata actttgcttc
    14281 accagaagta aaagaagcct tcttgaaagc aattgaagcg gccgaacaag tgttgaaaga
    14341 ccatgaaact agcacccaag atcaagtcaa tgaccgactt aataaattga cagaagctca
    14401 taaagctctg aatggtcaag agaaatttac ggaagaaaag acagagcttg atcgcttaac
    14461 aggtgaggtt caagaactct tggctgccaa accaaaccat ccttcaggtt ctgccctagc
    14521 tccgcttctt gagaaaaaca aggccttggt tgaaaaagta gatttgagtc cagaagagct
    14581 tacaacaacg aaacagagtc taaaagatct ggttgcttta ttgaaagaag acaagccagc
    14641 agtcttttct gatagtaaaa caggtgttga agtacacttc tcaaataaag agaagactgt
    14701 catcaagggt ttgaaagtag agcgtgttca agcaagtgct gaagagaaga aatactttgc
    14761 tggagaagat gctcatgtct ttgaaataga aggtttggat gaaaaaggtc aagatgttga
    14821 tctctcttac gcttctattg tgaaaatccc aattgaaaaa gataagaaag ttaagaaagt
    14881 atttttctta cctgaaggca aagaggcagt agaattggct tttgaacaaa cggatagtca
    14941 tgttatcttt acagcaccac actttactca ttatgccttt gtttatgaat ctgctgaaaa
    15001 accacaacct gctaaaccag caccacaaaa cacagtcctt ccaaaaccta cttatcaacc
    15061 ggcttctgat caacaaaagg ctcctaaatt ggaagttcaa gaggaaaagg ttgcctttca
    15121 tcgtcaagag catgaaaata ctgagatgct agttggggaa caacgagtca tcatacaggg
    15181 acgagatgga ctgttaagac atgtctttga agttgatgaa aacggtcagc gtcgtcttcg
    15241 ttcaacagaa gtcatccaag aagcgattcc agaaattgtt gaaattggaa caaaagtaaa
    15301 aacagtacca gcagtagtag ctacacagga aaaaccagct caaaatacag cagttaaatc
    15361 agaagaagca agcaaacaat tgccaaatac aggaacagct gatgctaatg aagccctaat
    15421 agcaggctta gccagccttg gtcttgctag tttagccttg accttgagac ggaaaagaaa
    15481 agataaagat taaatatcga aaaatcttgt gaaatctttc cttatatttc caaagtgtga
    15541 tataatagtt tcgaataaaa taaataaagg agtttttgta acatggcaaa acttactgtt
    15601 aaagacgttg acttgaaagg taaaaaagtc ctcgttcgtg ttgacttcaa cgtaccattg
    15661 aaagatggcg taatcactaa cgataaccgt atcacagcag ctcttccaac tattaagtac
    15721 atcatcgaac aaggtggacg tgcaattctt ttctctcacc ttggacgtgt gaaagaagaa
    15781 gctgataaag ctggtaaatc acttgctcct gtagcagctg acttggcagc aaaacttggt
    15841 caagatgttg ttttcccagg tgtcactcgt ggtgctgaat tggaagcggc aatcaacgct
    15901 cttgaagatg gacaagttct cttggttgaa aacactcgtt acgaagatgt tgacggcaag
    15961 aaagaatcta aaaacgatcc tgaacttggt aaatactggg catcacttgg agatggtatc
    16021 ttcgtaaacg atgcattcgg tacagctcac cgtgcacacg catctaacgt tggtatctca
    16081 gcaaacgttg aaaaagcagt tgctggtttc cttcttgaaa acgaaattgc ctacatccaa
    16141 gaagcagttg aaactccaga acgtccattc gtggctatcc ttggtggttc aaaagtttca
    16201 gacaagatcg gtgttatcga aaacttgctt gaaaaagctg ataaagtcct tatcggtggt
    16261 gggatgactt acacattcta caaagcacaa ggtatcgaaa tcggtaactc acttgtagaa
    16321 gaagacaaat tggatgttgc gaaagctctt cttgaaaaag caaatggtaa attgatcttg
    16381 ccagttgact caaaagaagc taacgcattt gctggttaca ctgaagtgcg tgacactgaa
    16441 ggtgaagcag tttctgaagg cttccttggt cttgacatcg gtccaaaatc tatcgccaaa
    16501 tttgacgaag ctttgactgg tgccaaaaca gttgtatgga acggacctat gggtgtattt
    16561 gaaaacccag atttccaagc tggtacaatc ggtgtgatgg acgctatcgt gaaacaacca
    16621 ggagttaaat caatcatcgg tggtggtgac tcagctgccg cagcgattaa ccttggccgt
    16681 gcagacaagt tctcatggat tagtacgggt ggtggagcat caatggaact tcttgaaggt
    16741 aaggttcttc caggacttgc agccttgaca gaaaaataag attttataaa taaatcaaag
    16801 aagagaggga tgaaagttcc tcttttcttt tgcttaaaat aaaaacgctt cctctcaact
    16861 attactcata aaaatcaccg atttatgata aaatggaaat agaaagttga gattatgagt
    16921 tattttaaaa aatataaatt cgataaatcc cagttcaaac ttggtatgag aacctttaaa
    16981 acaggtattg ctgtttttct agttctcttg atttttggct tttttggctg gaaaggtctt
    17041 caaattggtg ctttgacagc cgtttttagc ctgagggaga gttttgatga gagtgttcat
    17101 tttgggactt cgcgtattct aggaaatagt atcggtggac tctatgcctt ggtcttcttc
    17161 ttattaaata cctttttcca tgaagccttt tgggtgacct tggtagttgt tccaatctgc
    17221 accatgttaa ccattatgac aaatgtagcc atgaataaca aagcaggggt tattggtggt
    17281 gtagcagcta tgttaatcat taccctatca attccaagtg gtgagacaat ttcgtacgtg
    17341 tttgtgcgtg tatcagaaac gtttatggga gtttttgtcg caattatcgt aaattacgat
    17401 attgatcgta ttcgtctctt tttagagaaa aaagaaaaat aatgttacat tttataacat
    17461 tatcaattga cgtttgtctt tttttagact ataatagaca gaaagaagga aattgtaaat
    17521 gaaggaaaaa gaatttcgcc gaaatatggc tgtttttcct atcggcagtg ttatgaagtt
    17581 gaccgatcta tcggcgcgtc agattcgtta ttatgaagat caagagttga tcaagcccga
    17641 tcgaaacgaa ggaaatcgtc gcatgtattc cttgaatgac atggatcgtc tgcttgaaat
    17701 caaagattat atctctgaag gttataatat cgctgccatt aagaaaaaat atgctgaacg
    17761 tgaagcgaaa tccaagaaag cggttagtca gactgaagta cgtcgtgcac ttcacaatga
    17821 actcctccaa caggggcgtt ttgcttcagt acagtcacct tttggtcgcg gttaggcaac
    17881 cgcaagtagt catagattaa ggagaaaact tatgccaatc acagctgcag atattcgtcg
    17941 tgaagtcaag gaaaaaaatg ttacctttat tcgtcttatg ttctcagata ttttgggaac
    18001 catgaaaaac gtcgaaattc ctgctacaga tgaacagtta gataaggtct tgtcgaacaa
    18061 ggttatgttt gatggatctt ctattgaagg ttttgtacgt atcaatgagt cggatatgta
    18121 cttgtacccg gacttggata catggacagt cttcccttgg ggagatgaaa atggaagtgt
    18181 tgcaggtctg atctgtgatg tctatacaac agaaggtgaa ccatttgcgg gtgaccctcg
    18241 tggtaatttg aaacgagctc ttcgtcacat ggaagaagtt ggattcaaat ccttcaacct
    18301 tggtccagag ccagaattct tcctatttaa gttggatgaa aatggggacc caacacttga
    18361 agtgaatgac aagggtggct actttgattt ggcacctact gaccttgcgg acaacacacg
    18421 tcgtgagatt gtgaatgtct tgaccaaaat gggatttgaa gtagaagcga gtcaccacga
    18481 ggttgcggtt ggacagcatg agattgactt taagtacgat gaagttctcc gtgcttgtga
    18541 taagattcaa atctttaaac ttgttgttaa aaccattgct cgcaaacacg gactttacgc
    18601 aacatttatg gcgaagccaa aatttggtat tgctggctca ggtatgcact gtaatatgtc
    18661 cttgtttgat gcagaaggaa ataacgcctt ctttgatcca aatgatccaa aaggaatgca
    18721 gttgtcagaa acagcttacc atttcctagg cggtttgatc aagcatgctt acaactatac
    18781 tgccatcatg aacccaacag ttaactcata caaacgtttg gttccaggtt atgaagcgcc
    18841 tgtttacatt gcttgggctg gtcgtaaccg ttcgccactt gtgcgcgtac ctgcttcacg
    18901 tggtatggga actcgtcttg agttgcgttc agtggatcca atggcgaacc cttacgttgc
    18961 tatggctgtt cttttggaag ttggtttgta tggtattgaa aataaaatcg aagcaccagc
    19021 tcctatcgaa gaaaatatct acatcatgac agcagaagag cgcaaggaag ctggtattac
    19081 agaccttcca tcaactcttc acaacgcttt gaaagctttg acagaagatg aagtggttaa
    19141 agctgctctc ggagatcaca tctacactag cttccttgaa gccaaacgaa tcgaatgggc
    19201 aagttatgca accttcgttt cacaatggga aattgataat tatttagacc tttactaata
    19261 tagaagaaag attgcctgtg ggtaaacagt cacacagcag tctaagccat caaataccta
    19321 taacccttaa aatagcgatt tcggtcgcta tttatttttc gaaaaatcct cttgactctt
    19381 ttgcgaatta gatttatcat cagacgtgta gaagaaaatc aaggagtcac tatggaaaaa
    19441 ttcaatttca aaaacaatat cgggcaagaa aacaagttac ttcaaatcga aatctacaag
    19501 tttactaact tttgcaagct tcaaaattac acatctgtaa atattttttc gaaagatata
    19561 tttgaagcca tagtaaattg agactagaat agtacactac atctgctaaa aatttctaga
    19621 aactaattta actttcctaa tcgatttgtt tacatcttat ttcaatctac tatattatct
    19681 caataaatga tgatggcgac tgttttgttt gtgcttgtcg atttttgaat cctgatcgag
    19741 cggaagaata tttctgccga ggttgccaag gggaaaatcc tgaagatatt gaattttatg
    19801 atgaacaatt acaggcagaa aaggtggagg ttttgaatat tcgattggaa gtaaaaaatt
    19861 gaattatcta caatctcatc aacaataaac ctatttcaac cccattatct ataggcgtat
    19921 ttttacgcct ttttatatac ttgaagcaca ta
//
LOCUS       DAVMAH010000042        19431 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVMAH010000042 DAVMAH010000000
VERSION     DAVMAH010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19431
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.042"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            28..993
                     /locus_tag="VYO94_001476"
     CDS             28..993
                     /locus_tag="VYO94_001476"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV1760100.1"
                     /translation="MAIIKKIVVLYGGLSEEREVSENSAKEISKSLLTLGYDVISIDL
                     SQDCSYEIGEIEKSERGLNKQKVEIGSGIIDVCRKVDIVFLATHGGIGENGKLQAIFD
                     VEKIDYTGNSFLSTAISMDKKLSKIVASSVGIKCASNLMVDRIQANDFPIVIKPIRSG
                     SSKGIKIFQNKKQFDIYYKEHPELGSFFVEKYIKGREFSVGILGETVLPVIEIKVKNG
                     FYDYNNKYTVGAAEEVVPAKISEKLTHTLQKSAYKIHKALGFNVYSRTDFIVDEKGDV
                     YFIESNSLPGMTKTSLLPQEAKAAGIDFPNLCERIIELSREIRSQ"
     gene            1059..1295
                     /locus_tag="VYO94_001477"
     CDS             1059..1295
                     /locus_tag="VYO94_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760101.1"
                     /translation="MKIINGICRYIFDSKGFATIEVEIFLDSGDTGIGAAPRGSTTGH
                     YDIQYNEYYPRGNNFSPIPDGNIEFFRLYNICSG"
     gene            1393..1515
                     /locus_tag="VYO94_001478"
                     /pseudo
     CDS             1393..1515
                     /locus_tag="VYO94_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            1778..2206
                     /locus_tag="VYO94_001479"
     CDS             1778..2206
                     /locus_tag="VYO94_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760102.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            2275..2862
                     /locus_tag="VYO94_001480"
     CDS             2275..2862
                     /locus_tag="VYO94_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEV1760103.1"
                     /translation="MGGNPPIKNYTIVNKIVSSRKIERIVIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            3102..3380
                     /locus_tag="VYO94_001481"
     CDS             3102..3380
                     /locus_tag="VYO94_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HEV1760104.1"
                     /translation="MEKVASLGVPMCKPISIELCDDEVHSLHEWIDGRDAIDSILTYS
                     ENQQYTYGVEAGKILRKIHTIPATEVCEDWEIFFNLKIDDKISNEMIW"
     gene            3485..3814
                     /locus_tag="VYO94_001482"
                     /pseudo
     CDS             3485..3814
                     /locus_tag="VYO94_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3942..5171
                     /locus_tag="VYO94_001483"
     CDS             3942..5171
                     /locus_tag="VYO94_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1760105.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            5191..7887
                     /gene="ppc"
                     /locus_tag="VYO94_001484"
     CDS             5191..7887
                     /gene="ppc"
                     /locus_tag="VYO94_001484"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV1760106.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    7970..8187
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8300..9304
                     /locus_tag="VYO94_001485"
     CDS             8300..9304
                     /locus_tag="VYO94_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1760107.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPEFVLKEAGQVIE
                     "
     gene            9373..10239
                     /locus_tag="VYO94_001486"
     CDS             9373..10239
                     /locus_tag="VYO94_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1760108.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIIVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            10236..10994
                     /locus_tag="VYO94_001487"
     CDS             10236..10994
                     /locus_tag="VYO94_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760109.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLKQEEKAKMKISDYYQLFE"
     gene            11084..12844
                     /gene="dnaG"
                     /locus_tag="VYO94_001488"
     CDS             11084..12844
                     /gene="dnaG"
                     /locus_tag="VYO94_001488"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV1760110.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELIEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            12847..13956
                     /gene="rpoD"
                     /locus_tag="VYO94_001489"
     CDS             12847..13956
                     /gene="rpoD"
                     /locus_tag="VYO94_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV1760111.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            13970..14299
                     /locus_tag="VYO94_001490"
     CDS             13970..14299
                     /locus_tag="VYO94_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1760112.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            14414..15457
                     /gene="cpoA"
                     /locus_tag="VYO94_001491"
     CDS             14414..15457
                     /gene="cpoA"
                     /locus_tag="VYO94_001491"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV1760113.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            15473..16798
                     /locus_tag="VYO94_001492"
     CDS             15473..16798
                     /locus_tag="VYO94_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1760114.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            16829..17005
                     /locus_tag="VYO94_001493"
     CDS             16829..17005
                     /locus_tag="VYO94_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1760115.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVRVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            17064..17198
                     /locus_tag="VYO94_001494"
     CDS             17064..17198
                     /locus_tag="VYO94_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV1760116.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            17262..18572
                     /gene="obgE"
                     /locus_tag="VYO94_001495"
     CDS             17262..18572
                     /gene="obgE"
                     /locus_tag="VYO94_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV1760117.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPVPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            18582..18740
                     /locus_tag="VYO94_001496"
     CDS             18582..18740
                     /locus_tag="VYO94_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760118.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(18791..19369)
                     /locus_tag="VYO94_001497"
                     /pseudo
     CDS             complement(18791..19369)
                     /locus_tag="VYO94_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         6144 a         3222 c         4307 g         5758 t
ORIGIN      
        1 taagattcta ataaggaggt taagtgaatg gctattatta aaaaaattgt tgtactatat
       61 ggtggcctta gcgaagagag agaggtgtca gaaaattctg caaaggaaat tagtaaaagt
      121 ctattaacat tggggtatga tgtgatttct atagatttat ctcaagactg ttcgtacgag
      181 ataggagaaa ttgaaaaaag tgagcgcgga ttaaataaac aaaaagttga gattggttcg
      241 ggtattattg atgtttgtag aaaggttgat atagttttct tagcaactca tggtggaata
      301 ggtgagaatg ggaaactaca ggctattttt gatgtagaaa aaatagacta tacaggaaat
      361 tcgtttctta gtacagctat tagcatggat aaaaaattat caaaaatagt ggctagttct
      421 gttggaataa aatgtgcttc gaacttgatg gttgatagaa ttcaggcaaa tgattttcct
      481 attgttataa agccaattag aagtggttca agtaaaggta ttaagatatt tcaaaataaa
      541 aaacaatttg acatttatta taaagagcat cctgaacttg gttcattctt tgtagaaaag
      601 tatattaagg ggagagaatt ttcggtaggt attttaggtg aaactgtttt accggttatt
      661 gaaataaaag taaaaaatgg tttttatgat tataataaca agtacactgt tggtgcagct
      721 gaagaagtcg ttcccgcaaa aatatctgaa aagttaactc ataccttaca aaaatccgca
      781 tataaaatac ataaggctct tggatttaat gtttattcac gtactgattt tattgtagat
      841 gagaaggggg atgtatattt tattgaatca aatagtttac caggtatgac taaaacaagt
      901 ttattaccac aggaagcgaa agcagctggt atagatttcc caaacctatg tgaacgtatt
      961 attgagctga gtagggaaat tagatctcaa tagaaaataa aatcgacgac atttataaaa
     1021 aaagtaattt tcaatgataa aaaagaaagt ggaagcctat gaaaataatt aatggtattt
     1081 gcagatatat ctttgattca aaagggttcg caacaattga agtagagatt tttcttgata
     1141 gtggagatac tggaattggt gctgctccac gagggtctac aactgggcat tatgatattc
     1201 aatataatga gtattatcct agaggaaaca actttagtcc aataccagat ggaaatatag
     1261 aatttttcag gctctataat atttgtagtg ggtaaatccc ctatggatat tatggagcct
     1321 attttgggta gaaaaaaagt cccataagat ctataatgaa aagcgacaaa acaactcatt
     1381 agaaagaatc atatggaaca attacatttt atcacaaaat tactagacat taaagaccct
     1441 aatatccaga ttttagacat catcaataag gatacacaca aggaaatcat cgccaaactg
     1501 gactacgacg caccatgttg aggcagtatc actgcttgta caagctgagg catcagcgaa
     1561 gtagaagtaa atgatctccc atacgatagg actcgtagaa tgaggaggga aaccgacgaa
     1621 atgataaggt aagtccgaac cgctgagtgc gtggctctgc tcttccgatc tgagacagtc
     1681 gaaaagtaga aggggatggt attggtatca atcaatgagt aacaaagtat cagcatgatt
     1741 cgaaacattt acttgtaatt tgcggaggaa catcaatatg gatggaataa caaaagattt
     1801 tataaaaacg gctaaactaa tgaaacaatt atggccccaa ttgaccgata aagaagctat
     1861 tgatgaagta aaaaaatata cgaatggcaa aaatactgca atctttactg aagttgaagg
     1921 tgacacaatt gtaggtctag cactatgttc actcagattt gattatgttg aaggttgtaa
     1981 atatagtcct gttggattct tagaagggat tattgttgac gaggaatatc gtttaaagga
     2041 tattgctaaa aatctctgta caaaatgtga ggaatgggcg aaaaataaag gatgtaagga
     2101 atttgcaagt gactgtactt taacgaatac ggattctata agatttcatc tcaatattgg
     2161 atttcaggag gcaaatagaa ttattcattt taagaagaaa ttataatttc agaacgtggt
     2221 caaaatttat gtatctttag aaagcgtgaa agattggacg aacaaatttt tttgatgggt
     2281 ggaaatccgc cgataaagaa ctatacaatt gttaataaaa ttgtgtcatc aaggaagatc
     2341 gaaagaattg tcatttttac agtttttcga gaaaattggg aaccgtacat gaaaaagtac
     2401 acggaagttt ttcaaagtca atttcctaat ctaaacattg attacttgct cctggacact
     2461 gagcagattg atcttgatag ctatctagat gctgacataa ttatcatcgg tggtggaaat
     2521 acggaaaaat atattgctac ttatgttaat caggagttca aaagttatat cgatcatatg
     2581 cttaataaag aggcaaaaat tataggattt tctgcaggag ccctactatt aggagaaaaa
     2641 gtctatgtct cacctaatga taattcagat catcagataa agataaaaaa tggattagga
     2701 ctctttagtc agtttttaat tagtgtccat tatgattcct ggaatgataa agcaaataag
     2761 gatagagctg aagaactcgt taatgttccc ataattccac taaatgatca ttcttgtctt
     2821 gtattggata aacttggaaa catcatagag aaaattgact aactttcata atgtaaaaat
     2881 ggatctagga aataaaagtg tagacgaact ggataggtta ctagtgaaaa ctgcaaaaag
     2941 tgttgtaaag tgaatcggag tgttttagta gtaagatagc cataaataaa ggctggtcag
     3001 atgataaaaa atattgtgtg acagttcaaa atcagtaaac atatttcttg cgtgtttctg
     3061 ataagtcgaa gttagattat aaaaaaattg aatttgatac gatggagaaa gtagcttctc
     3121 ttggagttcc gatgtgtaaa ccaattagca ttgaactctg cgatgacgaa gtacattctt
     3181 tacacgaatg gatagacgga agagatgcaa tagatagcat tttaacttat tcagaaaacc
     3241 aacaatacac atatggtgta gaagcaggaa agatacttag aaagattcat acaattcctg
     3301 ctacagaagt ttgtgaagat tgggaaatct tttttaatct aaaaattgat gataaaatct
     3361 ccaacgaaat gatatggtaa gtccgaaacg ctcagtgtgt aagcttgttg ctaaaagcgt
     3421 aaaaaccttg gaacgaaagg aataatagac ttcctgcgaa acaaaaatac aatacaataa
     3481 aactatggat gatgaagcaa gtaaacaatt gagcgatagc cgtttcaaga tccttgtagg
     3541 tgttcagcgc acgacttttg aagagatgtt agctgtgtta aaaacagctt atcaacgtaa
     3601 acgcgcaaaa ggtggacgaa aaaccaaatt aagcctagac gatctcctta tggtaactat
     3661 tcaatacatg cgagaatagc gcacttatga acaaatttcg gctgattttg gcattcacga
     3721 aagcaactta atccgtcgga gtcaatgggt tgaagtaact cttgttcaaa atggttttac
     3781 gatttcaaat tctgctctaa ttatgaaaaa cagtaaaatt cgaaggatta taaggtaaga
     3841 gtttttttct ttctgaaaaa atggtataat agcaatcaaa actagaaaat aaaacggaat
     3901 ttggaacaga tttgtctgta tcctagtaga gtggtgatgc tatgaagatt agtaagaggc
     3961 acttattaaa ttattccatc ttgattccct acttgctttt atctattttg ggcttgattg
     4021 tggtctattc gaccaccagt gctattttaa ttgaagaagg caagagtgcc ttgcagttgg
     4081 ttcgaaacca aggaatcttt tggattgtta gtttgatact gattgcctta atttataaat
     4141 tgagactaga ttttttgaga aatgagcgac taatcatttt agttatatta atagaaatgc
     4201 ttttattgtt cttggctcgt tttattggta tttcagtaaa cggggcatac ggttggattt
     4261 cggttgcagg agtaactatt cagccagctg agtacttaaa aatcattatt atttggtatt
     4321 tagctcaccg attctccaaa cagcaagaag aaatagctac ttatgatttt caagttttga
     4381 ctcaaaatca atggcttccc cgtgctttta atgattggcg attcgttctc ctagttctga
     4441 ttggaagttt gggaattttc cctgatttag gaaatgcgac tattttagtc ttggtttcct
     4501 tgattatgta tacagttagt ggaatcgctt atcgctggtt ttcaaccatt ctggcgctcg
     4561 tatctgccgc ttctgtcttt gtcttgacca ctatcagcct aatcggtgtt gagacctttt
     4621 caaaaattcc agtattcggc tatgtagcca agcgctttag tgcctttttt aatccttttg
     4681 ccgatcgtgc tgatgcaggt caccagttag ctaattctta ttttgccatg gtcaatggcg
     4741 gttggtttgg tctaggtctt ggaaactcga ttgaaaaacg aggttatttg ccagaagctc
     4801 atacagactt tgtcttttct atcgtgattg aagaatttgg ctttgttggt gccagtctta
     4861 ttttagctct cttgtttttc atgattttgc ggattatctt ggtcggtatc cgagcggaga
     4921 atcctttcaa tgccatggtt gcactcggtg tcggagggat gatgttggtt caggtatttg
     4981 tcaatatcgg agggatttcg ggcttgattc catctacagg agtgactttc cccttcttat
     5041 cccagggtgg aaatagtctt ctagtcttat cagtggcagt agcctttgtc ttaaatattg
     5101 atgccagtga aaaacgcgct aaattgtacc gagaattgga aaatcaacca atgaaccttc
     5161 tgttgaagta ggataaagaa aggatagttt atgtctcttc aaaaattaga aaattatagt
     5221 aataaaagtg ttgtgcaaga agaagtcttg attctaacag aattactgga agatattact
     5281 aaaaatatgc ttgccccaga gacctttgaa aaaataatac agttgaaaga attatcaacg
     5341 caggaagatt atcaaggtct aaaccgtcta gtgactagct tatcaaatga tgaaatggtc
     5401 tatatttcac gctatttctc tatcttgcct cttttgatta atatttcaga ggatgtggat
     5461 ttagcttatg aaatcaatca tcaaaataat attgatcagg actatttagg taaattatct
     5521 acaacgatta aattggtagc agaaaaggaa aatgccgttg agatcctaga acacttgaat
     5581 gttgtccctg ttttgacagc ccatccaaca caagtgcaac gcaaaagtat gttggattta
     5641 acaaatcata ttcatagtct tttgcgtaaa taccgtgatg ttaagttggg gttgatcaat
     5701 aaagataaat ggtacaatga tttgcgtcgt tacatcgaaa ttatcatgca gacagacatg
     5761 attcgtgaga aaaaattaaa agtgactaac gaaatcacga atgctatgga atattataac
     5821 agctcctttt tgaaagctgt acctcatttg acgacggagt ataagcgctt agcgcaagcg
     5881 catggtctga atttaaaaca ggctaaacca atcaccatgg gtatgtggat aggtggtgat
     5941 cgtgatggaa atccatttgt tacagcaaag accttgaagc agtctgcact cactcagtgt
     6001 gaagtcatca tgaactacta tgataaaaag atttaccaac tttatcgtga attttctctt
     6061 tcaactagca ttgtcaacgt cagcaagcaa gtcagagaaa tggctcgtca atccaaggat
     6121 aactcgattt accgcgaaaa agagctttac cgtcgtgcct tgtttgatat tcaatcaaaa
     6181 attcaggcaa ctaaaaccta tctgattgag gatgaagaag ttgggactcg ttatgaaacc
     6241 gccaatgatt tctacaagga tttgattgcc attcgagatt ctctactaga aaataagggc
     6301 gagtccttga tttcaggtga ttttgtggaa ttattgcagg cagtagagat atttggtttt
     6361 tacttagcat caattgatat gcgacaagac tctagcgtct atgaagcctg tgtggcagaa
     6421 ctcttgaaat cagcaggaat tcattctcgt tatagcgagt tgagcgaaga agaaaagtgt
     6481 gaccttctct tgaaagaatt agaagaagat ccccgaattc tttctgcgac tcacgcagaa
     6541 aaatcagaat tattagcaaa agaattagct atttttaaga cggctcgtgt tttgaaagat
     6601 aagttgggag atgatgtcat ccgtcagacc atcatttcac atgcaaccag cctttctgat
     6661 atgctagaat tagctattct gttaaaagaa gtaggactgg tggatacgga aagggcgcgt
     6721 gttcagattg ttcccctttt tgaaacaatt gaagacttgg atcattcaga ggaaacaatg
     6781 agaaaatatc tttctcttag ccttgccaaa aaatggattg actcacgaaa taactaccaa
     6841 gaaatcatgc ttggctactc tgacagtaat aaagatggcg gttacttgtc atcatgttgg
     6901 accctctaca aggctcaaca acaattgact gctattggag atgaatttgg cgttaaggtt
     6961 accttcttcc atggtcgtgg tggtactgtc ggtcgtggtg gtgggccaac ctatgaagcc
     7021 attacatctc aaccgctcaa gtctatcaag gatcgtatcc gcttgacgga gcagggtgaa
     7081 gtaattggga ataaatacgg taacaaagac gccgcttact ataaccttga aatgctagta
     7141 tcggcagcta ttaaccgtat gattactcag aagaagagcg ataccaatac cccaaatcgt
     7201 tatgaagcca ttatggatca agtagtggac cgtagttacg atatctaccg tgatttggtc
     7261 tttggtaatg agcatttcta tgattatttc ttcgagtcaa gtccaatcaa ggctatttca
     7321 agttttaata ttggttctcg tccagccgct cgtaagacta ttactgaaat cggtggtttg
     7381 cgtgccatcc cttgggtatt ctcatggtca cagagtcgtg ttatgttccc tggatggtac
     7441 ggggttggtt caagcttcaa ggaatttatc aataaaaatc cagagaatat tgctatctta
     7501 cgagatatgt accaaaattg gcctttcttc caatcgcttc tttcaaatgt tgatatggtt
     7561 ttgtcaaaat caaatatgaa tattgctttt gaatatgcta aactttgtga agacgagcaa
     7621 gttaaggcca tctatgagac tattttaaat gaatggcaag ttactaagaa cgttatcttg
     7681 gctattgaag gacatgacga actcttagct gacaatccat atctaaaagc tagtctggat
     7741 taccgtatgc cttactttaa tattctcaac tatattcagt tagagttgat taaacgccaa
     7801 cgtcgtggag aattgtccag tgatcaagaa cgattgattc atatcaccat caacggaatt
     7861 gcgacaggat tgcgtaattc aggttgataa ttttcaagag tgaatgctaa aagtgaatat
     7921 caaaaaaatt ctaatagact attgacaagt agtttaaaaa tgatataatt taaccattca
     7981 gaaaagtaat catacaaact ttttagagag tctgtggtag ctgaaaacag ataagtggca
     8041 atgatgaaaa ttgggctgaa tgctatttag aatttgaaat tataaaaatt cggtaagcac
     8101 accttacagt gcatctcgtt attgcgagac tgagcgatag ggaaattccc tataattgag
     8161 gtggtaccgc gcatcgacgt cctcacacaa gttttttgtg tgaggatttt tttgatggag
     8221 gttagtatag aaagaaaacg atggcgtcgc ttgtttagat aagtgaaata tgttaaagga
     8281 aataaaaagg agaaacagaa tgaaaaataa acgtttaatt ggaattattg ctgcattagc
     8341 agtcttagta gcaggaagct tgatttattc ttcaatgaat aaatcagaag ctcagaataa
     8401 taaggatgag aagaaaataa ccaagattgg tgtgcttcaa tttgtgagcc atccatccct
     8461 tgatttgatt tataaaggga tccaagatgg acttgcagaa gaaggatata aagatgatca
     8521 agttaaaatt gattttatga actcagaagg tgaccaaagt aaggttgcga caatgagtaa
     8581 acaattggtt gcaaatggga atgaccttgt ggttggtatc gcaacaccag cagcccaagg
     8641 gttggctagt gcaacaaaag acctaccggt tatcatggcc gctattacag acccaattgg
     8701 tgctaacttg gttaaagatt tgaaaaaacc aggtggcaac attacagggg tatctgacca
     8761 caatccagct caacaacaag ttgaactcat caaggctctg acaccgaatg tgaaaacaat
     8821 cggagctctt tactcaagta gcgaagacaa ttcaaaaaca caggtcgaag aatttaaggc
     8881 ttatgctgaa aaagcaggtc tgacagtgga aacatttgca gttccttcaa caaatgaaat
     8941 tgcctcaact gtcactgtta tgactagcaa ggtagatgct atttgggttc caattgataa
     9001 caccattgca tcaggatttc caacggttgt ctctagcaat caaagttcta agaaaccaat
     9061 ttatcccagt gcgacagcta tggtagaagt aggtggtttg gcatcagttg taattgacca
     9121 acatgacctt ggtgtggcaa caggtaaaat gattgtgcaa gtcttgaaag gtgcaaaacc
     9181 agccgatacc ccagtcaatg tcttttcaac tggtaagtca gtcatcaata aaaaaatagc
     9241 acaagaacta ggtattacta ttcctgagtt tgttctcaaa gaagcaggac aagtcatcga
     9301 ataaataagg tagggaggag gagactcttc ccatttttta aaaagatgaa tatagaaagg
     9361 attaaataaa atatgattgt ttccattatt tctcaaggat ttgtctgggc tattctaggt
     9421 ctgggaatct ttatgacatt taggatttta aactttccag atatgacgac agaaggttcc
     9481 ttccctcttg ggggagctgt tgctgtcact ttgataacca aaggcgtgaa cccattttta
     9541 gcgacacttg ttgctgtagg agcaggttgt ttggctggaa tggcagcagg ccttctttat
     9601 acaaaaggga agatcccaac cttgctctca gggattttgg tgatgacttc ttgtcactca
     9661 atcatgctct tgattatggg acgtgcaaat ttaggcctgc ttggaaccaa gcaaattcag
     9721 gatgttttgc cttttgattc ggatttgaat caactcttga caggtctcat ctttgtgagc
     9781 attgttattg ctctcatgct ctttttcttg gacactaaac tcggacaagc ctatattgct
     9841 acaggggata atcctgatat ggctagaagt tttgggattc atactggacg catggagctc
     9901 atgggcttgg tcttatcaaa tggtgtgatt gcccttgcag gtgccctcat tgctcagcaa
     9961 gaaggttatg ccgatgtgtc tcgagggatc ggggttatcg ttgtggggct tgcaagtttg
    10021 attattggag aagttatttt caagagtttg agcttggcag agcgtttggt tactatcatt
    10081 gtaggttcta tcgcttatca atttttagtg tgggcagtta tcgcacttgg ctttaataca
    10141 agttaccttc gtttatacag tgccttgatt ttagcagtct gcctcatgat tccaacattt
    10201 aagcaaacaa tcttgaaagg agccaagtta agcaaatgac agcaattgta gaattaaaaa
    10261 atgcaaccaa aatcgttaaa aatggctttg atgaagaaaa gattatttta aatgatgttt
    10321 ccttagaaat ttttgaacag gactttatca cgattttggg tggaaatggt gctggtaaat
    10381 caaccctctt taacactatt gcaggaacca tatcactaac cagtggaact atccgtattt
    10441 taggtgagga tgttaccaag ttttcaccag agaagcgcgc taagtatctg tctcgagtct
    10501 tccaagatcc aaagatgggg acagctcctc gtatgacagt ggcagagaat ctcctgattg
    10561 ccaagtttcg tggtgaaaag cgtggactat ttccgagacg tctggctagc tataaggata
    10621 agtttcaggc gaccattgaa aaagtgggaa acggtcttga gaaacacttg aatacaccga
    10681 ttgagttctt atctggtgga caaagacagg ctttgagtct cttgatggca accttgaagc
    10741 gacctgaatt actcttgtta gacgagcata ctgctgccct ggatccaaag actagtgttg
    10801 ctttgatgga attgacagat gaatttgtta agaaagatca attgacagcc cttatgatta
    10861 cccatcatat ggaagatgct ctcaaatatg gcaatcgctt gattgtcatg aaagaaggac
    10921 gggttatcca agatttgaaa caagaagaaa aagcaaaaat gaaaatctct gattattatc
    10981 aactctttga ataaagtagg gaaaatgagt gaaatggttt actttttttc tgaaataaag
    11041 tatactatat aaagtaaact atgataacat ggaggtattg tgtatggttg acaaacaagt
    11101 cattgaagaa atcaaaaaca atgccaacat tgtggaagtc ataggagatg tgatttcttt
    11161 acaaaaggca ggacggaact atctagggct ctgtcctttt catggtgaaa aaacaccttc
    11221 tttcaacgtt gtagaggaca agcagtttta ccactgtttt ggttgtggtc gctcaggtga
    11281 tgtctttaaa ttcatcgagg agtaccaagg ggttaccttt atggaggctg tccaaatctt
    11341 aggtcagcgt gtcgggattg aggttgaaaa accgctttat agtgagcaga agccagcctc
    11401 gcctcaccaa gctctttatg atatgcacga agatgcggct aaattttacc atgctattct
    11461 catgacaacg actatgggcg aagaggccag aaattacctt tatcagcggg gtttgacaga
    11521 tgaagtgctt aaacattttt ggattggttt agcacctcca gaacgaaact atctctatca
    11581 acgtttgtct gatcagtatc gtgaagagga tttactggat tcaggcctgt tttatctctc
    11641 ggatgccaat caatttgtag acacctttca caatcgcatt atgtttcccc tgacaaatga
    11701 ccaaggaaag gtcattgcct tctcaggtcg tatctggcaa aaaacggatt cacaaacttc
    11761 taagtataaa aacagccgat cgactgcaat ttttaacaaa agttacgaat tatatcatat
    11821 ggatagggca aaaaaatctt ctggaaaaac tagtgagatt tacctgatgg aaggattcat
    11881 ggatgttatt gcagcctatc gggctggaat cgaaaatgct gtggcgtcaa tgggaacggc
    11941 cttgagtaga gagcatgttg agcatctgaa aaggttaacc aagaaattgg ttcttgttta
    12001 cgatggagat aaggctgggc aagccgcgat attgaaagca ttggatgaaa ttggtgatat
    12061 gcctgtgcaa atcgttagca tgcctgataa cttggatcct gatgagtatc tacaaaaaaa
    12121 tggtccagaa gacttggcct atctattaac gaaaactcgt attagtccga ttgagttcta
    12181 cattcatcag tacaaacctg aaaacagtga aaatctgcag gctcagattg agtttattga
    12241 aaaaatagct cccttgattg ttcaagaaaa gtccatcgct gctcaaaaca gctatattca
    12301 tattttagct gacagtctgg cgtcctttga ttatgcccag attgagcaga ttgttaatga
    12361 gagtcgtcag gtgcaaaggc agaatcgcat ggaaggaatt tccagaccga cgccaatcac
    12421 catgcctatc accaagcagt tatcggctat tatgagggca gaagcccatc tactctatcg
    12481 gatgatggaa tcccctcttg ttttgaacga ttaccgtttg cgagaagact ttgcatttgc
    12541 tacacctgaa tttcaggtct tatatgactt gcttggccag tatggaaatc ttcctccaga
    12601 agttttagca gagcagacag aggaagttga aagagcttgg taccaagttt tagctcagga
    12661 tttgcctgct gagatatcgc cgcaggaact tattgaagta gagatgactc gaaacaaggc
    12721 tctcttgaat caggacaata tgagaatcaa aaagaaggtg caggaagcta gccatgtagg
    12781 agatacagat acagccctag aagaattgga acgtttaatt tcccaaaaga gaagaatgga
    12841 gtaataatgg caacaaaaca aaaagaagta acaacatttg acgtacaggt agcagaattt
    12901 atccgtaatc ataagcaaaa agggacagca acagatgatg aaatcaatgc aagtctggtt
    12961 attcctttta ccttggacgc tgatgggatt gaagatctct tgcaacggat tcaggatgca
    13021 ggcatttcta tcacagataa cgaaggaaat ccaagtgcgc gtgttcttag caatgaagaa
    13081 gaaccagaac tcagcgatga ggacttgatt gggtcaactt ctgctaaggt caatgaccct
    13141 gtccgtatgt acttgaaaga aataggggtc gttcctctct tgaccaatga agaggagaaa
    13201 gagttggcac tggctgttga agctggtgat atcgaagcca aacaacgtct tgcggaagcc
    13261 aatcttcgtt tggttgtttc cattgccaaa cgctatgtcg gtcgtggtat gcagttcctt
    13321 gacttgattc aagaaggaaa tatgggcttg atgaaggcgg ttgacaagtt tgactattct
    13381 aaagggttca agttttcaac ttatgcaact tggtggattc gtcaggctat cactcgtgct
    13441 attgcggacc aagctcgtac catccgtatc ccagttcaca tggttgaaac tatcaataaa
    13501 ttggttcgtg aacagcggaa tctccttcaa gaattggggc aagatccgac accagaacag
    13561 attgctgaac gaatggatat gacacctgat aaggttcgtg aaatcttgaa gattgcccaa
    13621 gaaccagtat ctcttgaaac tcctatcggt gaagaggacg atagccacct tggagacttt
    13681 atcgaagatg aagtgattga aaatccagtg gattatacga ctcgtatcgt cttgcgtgag
    13741 caattggatg aaatcttaga tactcttaca gaccgtgaag aaaatgttct gcgtctacgt
    13801 tttggactag atgatggaaa aatgcgcaca cttgaagatg tggggaaagt ctttaacgta
    13861 actcgtgagc gtatccgtca gattgaagca aaggctttga gaaaactacg ccaaccaagt
    13921 cgtagcaaac cgcttcgtga ttttattgaa gactaagagt gaggaaaata tggcttatac
    13981 agaagagcaa attgaaaaca tcaaaacacg gattttaaca gccttggaag aagtcatcga
    14041 ccctgagttg ggaatcgata ttgtcaatct tggtttgatc tatgagattc gttttgacgg
    14101 tgacacaggg caaacagaga ttgacatgac tttgacaact atgggttgtc ccttagcaga
    14161 ccttttgaca gaccagattt atgatgctat gatagaggtt ccagaagtaa cggatactga
    14221 ggttaaatta gtctggtatc cagcctggac agttgaaaaa atgagtcgct atgcccgcat
    14281 tgccctaggc attaagtaaa catataaaag catgtgagag actgttggaa aagcgaggaa
    14341 atttcccctc ttttcctcta gtctctcctt tcttttgctg attttattca aagaaaatga
    14401 tataatagta gttatggaga aaaagaaatt acgcatcaat atgttgagtt caagtgagaa
    14461 agtagcagga cagggagttt caggtgctta ccgtgaatta gttcgtcttc ttcaccgtgc
    14521 tgccaaggac caattgattg ttacagaaaa tcttccaatc gaggcagatg tgactcactt
    14581 tcatacgatt gattttccct attatttatc aaccttccaa aagaaacgct cagggagaaa
    14641 gattggctat gtgcatttct tgccagctac acttgaggga agtttgaaaa ttccattttt
    14701 cttaaaggga attgtgaaac gctatgtatt ttctttttac aaccggatgg agcacttggt
    14761 tgtggtcaat cctatgttta ttgaggattt ggtagcagct ggtattccac gtgaaaaagt
    14821 gacctatatt cctaactttg tcaacaagga aaaatggcat cctctaccac aagaagaggt
    14881 agtcagactg cgcacagatc ttggtcttag tgacaatcag tttatcgtag taggtgctgg
    14941 gcaagttcag aaacgtaaag ggattgatga ctttatccgt ctggctgagg aattgcctca
    15001 gattaccttt atctgggctg gtggcttctc ttttggtggt atgacagatg gttatgaaca
    15061 ctataagaaa attatggaaa atccccctaa aaatttgatt tttccaggca ttgtatcgcc
    15121 agagcggatg cgcgaattgt atgctctagc ggatcttttc ttgttgccta gttacaatga
    15181 gctctttcct atgactattt tagaagctgc gagttgtgag gctcctatta tgttgcgtga
    15241 tttagatctc tataaggtaa ttttggaggg aaattatcgg gcgacagcgg gtagagaaga
    15301 gatgaaagag gctattttgg aatatcaagc aaatcctgct gccttaaaag atctcaaaga
    15361 aaaggctaag aatatttcca gagagtattc tgaagagcat ctgttacaaa tctggttgga
    15421 cttttatgag aaacaagccg ctttagggag aaagtaaaaa gtgaggtaat ctatgcgaat
    15481 tggtttattt acagatacct attttcctca ggtttctggt gttgcgacca gtattcgaac
    15541 cttgaaaaca gaacttgaaa agcagggaca tgctgttttt atctttacga cgacagataa
    15601 ggatgtcaat cgctacgaag attggcaaat tatccgcatt ccaagtgttc ctttctttgc
    15661 ttttaaggat cgtcgctttg cctaccgagg ttttagcaag gcacttgaaa ttgctaaaca
    15721 gtatcagcta gatattatcc atactcagac agaattttct cttggcctgt tggggatttg
    15781 gattgcgcgt gaattgaaaa ttccagtcat ccatacctat cacacccagt atgaagacta
    15841 tgtccattat attgctaagg ggatgttgat ccggccgagt atggtcaagt atctggttag
    15901 aggtttcctg catgatgtgg atggggttat ttgtcctagt gagattgtcc gtgacttgct
    15961 atctgattat aaggtcaagg ttgaaaaacg ggtcattcct actgggattg aattagccaa
    16021 gtttgagcgt ccggaaatca agcaggaaaa tttgaaagaa ctgcgtagta aactagggat
    16081 tcaagatggt gaaaagacgt tgcttagtct ttcgagaatc tcctatgaaa aaaatattca
    16141 agcagtttta gcagcctttg ctgatgttct gaaagaggaa gacaaggtta aactggtagt
    16201 agctggggat ggcccttatc tgaatgacct caaagagcaa gctcagaacc tagagattca
    16261 agactcagtc atctttacag ggatgattgc tcctagtgag acggctcttt actataaagc
    16321 ggcggatttc ttcatttcgg catcgacaag cgaaacgcaa ggtttgacct acttggaaag
    16381 cttagccagt ggaacacctg tcattgctca cggaaatcct tatttgaaca acctcatcag
    16441 tgataaaatg tttggaacct tgtactatgg agaacatgat ttggctggtg ctattttgga
    16501 agccctgatt gcaacaccag acatgaatga gcatacctta tcagagaaat tgtatgagat
    16561 ttcagctgag aactttggga aacgagtgca tgagttttat ctggatgcca ttatttcaaa
    16621 taacttccag aaagatttgg ctaaagatga tacggtcagt cagcgtatct ttaagacagt
    16681 tttgtatctt ccgcaacagg tggttgctgt acctgtaaaa ggatctagac gcatgttgaa
    16741 ggcttcaaaa acacagttga tcagtatgag agactattgg aaagaccatg aagaatagaa
    16801 agaggaacag ctatgaaaaa aacaattaat gagaagcggt cgtgataaaa agattgcggg
    16861 tgtttgtgct ggggtggccc attatctgga tatggatccg actatcgttc gagtcatttg
    16921 gggtgttctt acttgctgtt acggagctgg aattgtagct tacattattt tatggattat
    16981 cgcaccagta gcaactgact attgaaaact agctcaattc atgctaagat aatagaaaat
    17041 agaatgtaac gaaggagaga aaaatggcat ttggagataa tggaaatcgt aaaaaaacta
    17101 tgtttgagaa aataaccttg tttatcgtga ttatcatgct agtagcaagt ttattgggaa
    17161 tttttgcaac tgcaattggt gccctcagta atctataaaa tagattcaag aaaatttagt
    17221 gactgggatt tcccagccct tttttaaagt gagaagaaat aatgagtatg tttttagata
    17281 cagctaagat taaggtcaag gctggtaatg gtggcgatgg tatggttgcc tttcgtcgtg
    17341 aaaaatatgt ccctaatgga ggcccttggg gtggtgatgg tggtcgtgga ggcaatgtgg
    17401 tcttcgttgt agacgaagga ctacgtacct tgatggattt ccgctacaat cgtcatttca
    17461 aggctgattc tggtgaaaaa gggatgacca aagggatgca tggtcgtggt gctgaggacc
    17521 ttagagttcg agtaccacaa ggtacgactg ttcgtgatgc ggagactggc aaggttttaa
    17581 cagatttgat tgaacatggg caagaattta tcgttgccca cggtggtcgt ggtggacgtg
    17641 gaaatattcg tttcgcgaca ccaaaaaatc ctgtaccgga aatctctgaa aatggagaac
    17701 caggtcagga acgtgagtta caattggaac taaaaatctt ggcagatgtc ggtttagtag
    17761 gattcccatc tgtagggaag tcaacacttt taagtgttat tacctcagct aagcctaaaa
    17821 ttggtgccta ccactttacc actattgtac caaatttagg tatggttcgc acccaatcag
    17881 gtgaatcctt tgcagtagcc gacttgccag gtttgattga aggggctagt caaggtgttg
    17941 gtttgggaac tcagtttctc cgtcacatcg agcgtacacg tgttatcctt cacatcattg
    18001 atatgtcagc tagcgaaggc cgtgatccat atgaggatta cctagctatc aataaagagc
    18061 tggagtctta caatcttcgc ctcatggagc gtccacagat tattgtagct aataagatgg
    18121 acatgcctga gagtcaggaa aatcttgaag aatttaagaa aaaattgtct gaaaattatg
    18181 atgaatttga agagttacca gctatcttcc caatttctgg attgaccaag caaggtctgg
    18241 caacactttt agatgctaca gctgaattgt tagacaagac accagaattt ttgctctacg
    18301 acgagtccga tatggaagaa gaagcttact atggatttga cgaagaagaa aaagcctttg
    18361 aaattagtcg tgatgacgat gcgacatggg tactttctgg tgaaaaactc atgaaactct
    18421 ttaatatgac caactttgat cgtgatgaat ctgtcatgaa atttgcccgt cagcttcgtg
    18481 gtatgggggt tgatgaagcc cttcgtgcgc gtggagctaa agatggggat ttggtccgca
    18541 ttggtaaatt tgagtttgaa tttgtagact aggagactgg tatgggagat aaaccgatat
    18601 ctttccgaga tgcggatggt aattttgttt ccgccgcaga cgtttggaat gaaaagaaat
    18661 tggaagaact atttaatcgt ctcaatccaa atcgtgcctt gagattggca cgaactaaaa
    18721 aggaaaatcc atctcagtaa agaagctaaa aaatcccggc tctttgtcaa ctgtagtggg
    18781 ttgaagtcag ctaagcttga gaaaggacaa attttgtcct ttcttttttg atgttcagag
    18841 cgacgaaaat ccgttttttg aagttttcaa agtttcgaaa accaaaggca ttgcgcttga
    18901 taagtttgat gagattattg gtcgcttcca gtttggcgtt agaatagtgt agttgaaggg
    18961 tgttgacaag cttttcttta tctttgagga aggttttaaa gacagtctga aaaataggat
    19021 gaacctgctt aagattgtcc tcaataagtc cgaaaaattt ctcagggtct ttgttctgaa
    19081 agtgaaaaag taagagttga tagatctgat agtggtgttt caagtcttcc gaataactca
    19141 aaagcttgtt taaaatctct ttattggtta agtgcatacg aaaagtagga cgataaaatc
    19201 gcttatcact cagtttacgg ctatcctgtt gtatgagctt ccagtagcgc ttgatagcct
    19261 tgtattcatg agactttcga tgaaactgat tcatgatttg aacacgcaca cgactcatag
    19321 cacggctaag atgttgtaca atgtgaaagc gatcaagaac gattttagca ttcgggagtg
    19381 aaacagtctg ggagactgtt tcagcctgag cctagaaatt tgaaagcgaa g
//
LOCUS       DAVMAH010000043        19121 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVMAH010000043 DAVMAH010000000
VERSION     DAVMAH010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19121
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.043"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(101..376)
                     /locus_tag="VYO94_001498"
     CDS             complement(101..376)
                     /locus_tag="VYO94_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV1760119.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(483..1322)
                     /locus_tag="VYO94_001499"
     CDS             complement(483..1322)
                     /locus_tag="VYO94_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1760120.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1464..2312
                     /locus_tag="VYO94_001500"
     CDS             1464..2312
                     /locus_tag="VYO94_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1760121.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2405..3322)
                     /locus_tag="VYO94_001501"
     CDS             complement(2405..3322)
                     /locus_tag="VYO94_001501"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV1760122.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3760..3965
                     /locus_tag="VYO94_001502"
                     /pseudo
     CDS             3760..3965
                     /locus_tag="VYO94_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4276..4569)
                     /gene="rpmA"
                     /locus_tag="VYO94_001503"
     CDS             complement(4276..4569)
                     /gene="rpmA"
                     /locus_tag="VYO94_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV1760123.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4586..4930)
                     /locus_tag="VYO94_001504"
     CDS             complement(4586..4930)
                     /locus_tag="VYO94_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV1760124.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4946..5260)
                     /gene="rplU"
                     /locus_tag="VYO94_001505"
     CDS             complement(4946..5260)
                     /gene="rplU"
                     /locus_tag="VYO94_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV1760125.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5296..5383)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5448..6056)
                     /locus_tag="VYO94_001506"
     CDS             complement(5448..6056)
                     /locus_tag="VYO94_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV1760126.1"
                     /translation="MDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVRDKLLTLI
                     AFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIAFVPQTVDNIYLVPPLAFCMGL
                     VTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLLSSFVLGV
                     VFSAYLTIFYHEKTILGVPIMMSVFYLSMLFASWQKKVKEKA"
     gene            6547..6846
                     /locus_tag="VYO94_001507"
     CDS             6547..6846
                     /locus_tag="VYO94_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV1760127.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVISIDFNPAVIDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            complement(7187..8161)
                     /gene="pta"
                     /locus_tag="VYO94_001508"
     CDS             complement(7187..8161)
                     /gene="pta"
                     /locus_tag="VYO94_001508"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV1760128.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(8205..9101)
                     /locus_tag="VYO94_001509"
     CDS             complement(8205..9101)
                     /locus_tag="VYO94_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1760129.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMIFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(9098..9916)
                     /locus_tag="VYO94_001510"
     CDS             complement(9098..9916)
                     /locus_tag="VYO94_001510"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV1760130.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(9900..10571)
                     /locus_tag="VYO94_001511"
     CDS             complement(9900..10571)
                     /locus_tag="VYO94_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV1760131.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            10699..11268
                     /locus_tag="VYO94_001512"
     CDS             10699..11268
                     /locus_tag="VYO94_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV1760132.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            11381..12340
                     /locus_tag="VYO94_001513"
     CDS             11381..12340
                     /locus_tag="VYO94_001513"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1760133.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            12350..13465
                     /locus_tag="VYO94_001514"
     CDS             12350..13465
                     /locus_tag="VYO94_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1760134.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     KTIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            13470..13817
                     /locus_tag="VYO94_001515"
     CDS             13470..13817
                     /locus_tag="VYO94_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV1760135.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            13825..14040
                     /locus_tag="VYO94_001516"
     CDS             13825..14040
                     /locus_tag="VYO94_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1760136.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            14123..14764
                     /locus_tag="VYO94_001517"
     CDS             14123..14764
                     /locus_tag="VYO94_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV1760137.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            14782..15471
                     /locus_tag="VYO94_001518"
     CDS             14782..15471
                     /locus_tag="VYO94_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1760138.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(15468..16148)
                     /gene="radC"
                     /locus_tag="VYO94_001519"
     CDS             complement(15468..16148)
                     /gene="radC"
                     /locus_tag="VYO94_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV1760139.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQVSV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(16191..18482)
                     /gene="pcrA"
                     /locus_tag="VYO94_001520"
     CDS             complement(16191..18482)
                     /gene="pcrA"
                     /locus_tag="VYO94_001520"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV1760140.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYVAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQNRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(18673..19121)
                     /locus_tag="VYO94_001521"
                     /pseudo
     CDS             complement(18673..19121)
                     /locus_tag="VYO94_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5854 a         4024 c         3476 g         5767 t
ORIGIN      
        1 aacattcaac tttttaactc tatttattac tagatttcat aattaaaaag cctactgacc
       61 aagctagaaa gcttgataca ataggctttt taaagactga ttatttaaca gcgtctttaa
      121 gagctttacc agctttgaat gctggtactt tagaagctgc aattgtcatt tctttaccag
      181 tttgtgggtt gcgaccttta cgttctgcgc gctcacgaac ttcaaagtta ccaaaaccga
      241 tcaactgaac tttttcacca gctgcaagat agtcagctac tgctgcaaat acagcttcaa
      301 ctgctgctgc tgagtctttc ttagtcaatt ctgtagcttc tgctacttta gcgatcaaat
      361 cttgtttgtt tgccatgtta atgattcctc caaataattt ctaattaaca aatataatca
      421 tatcctaaaa tcccttttag gtcaagttaa aaacgctatt tcttcccatt ttatttattt
      481 ttttaggagt ggtaacgtat caaaatagcc caagcgttct cacccgtgtg agtttgaata
      541 atggaacccg tttccaaaac agaaattggc ttttcaacat aagcttgtaa gctttctttc
      601 atctcttttg cccaatcatc actaccagaa tatgaaattc caatctctgc tacagcacgt
      661 tcagaaagcg atgttatcaa ctcatctaac cattttttaa atgttttagt tccacgacct
      721 ttaaccattg gctgcaattc atggtctttc atttgcatga caacacggat attgagaaga
      781 gagctcaaca agccagttac acggctaatt cgtccacctt tgacaagatt ttccaaagtt
      841 gaaacaccaa tataaagctc tgtatggttt ttaacctctt ctacatgaga taaaattgcc
      901 tccatatctt taccttcttg agctaacttc gcagcctcaa caacttggaa tttcagggct
      961 tggtcagtga aggaactatc aacaacagtc acatctgcag tagataggct agcaccttgg
     1021 cgtgctgctt ctaccgtacc cgaaagagca tgggacatat gaatagcaag aatctggcca
     1081 ccatctttgc ataggtcttc aaaaatctca gcaaagacac ctacaggtgg ctgacttgtt
     1141 ttcggaagat tcttactttc ttgcatcaac tgaagaaatt taccttcttc tttcaaatcc
     1201 gcatcagaat aaacaacatt atcaatcatt acagataatg gaacaattgt aatatctaat
     1261 tgctttacta gttcaggttc aatagtaaca gatgaatcgg ttacaatctt aatttttgtc
     1321 atagtatcaa tctttctatt ttaggattca gattggtttc cttacttcta attatatcaa
     1381 aaaaaagatt aaaaatccta atggagtcaa tcaaattttc cgtaaaattt gatataatca
     1441 acttataaga aaagaggtgt cctatgatta aaaaaattta ccccattttt accattttac
     1501 taggtgctgc tatttatgct tttggactga cttattttgt agttccccat catctctttg
     1561 aaggaggggc gacaggcatt accctcatca ccttttatct ttttaaaatc cctgtttccc
     1621 tcatgaacct gctgattaat attccccttt tcatcctagc ttggaagatc tttggagcca
     1681 aatccctcta ttctagttta ctaggaacct tagctttgtc cgcctggtta gctttttttg
     1741 agcatattcc ccttcatatt gatcttcaag gtgatttact aatcacagcc cttatagcgg
     1801 gaatcctatt gggaattggc cttggaatta tttttaatgc tggaggtaca actggcggaa
     1861 ctgatattct agctcgtatt ctcaacaaat acactcatat atccatagga aaactgctct
     1921 ttatcttaga tttttgtatt ctcatgttga ttctcctaat cttcaaggat ttgagattgg
     1981 tttcctacac gcttttgttt gattttattg tttctcgtgt tattgatttg attggtgaag
     2041 gaggatatgc cggcaaaggc tttatgatta tcacaaaacg tcctgaccaa cttgctaagg
     2101 cgattaatga tgacctcgga agaggtgtta cttttatttc tggtcaaggc tactatagta
     2161 aagaaaattt gaaaatcatc tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg
     2221 aaatgattca tcgaatcgat cctcaagcct ttataactat tacagaagcc catgaaatcc
     2281 taggagaagg cttcaccttt gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt
     2341 tagactaaat catctatctt ttgggttaca gacaacctct tttttgtttt atttactcaa
     2401 gctcttaaga ccaattccga gttacttctt catcagcctt taactgatcc actaattggt
     2461 caactgagtc aaatttggtc atatcacgaa tgcgatcaag ccaataaacc atgacggttt
     2521 ccccataaat atcttgatta aaatcaaaaa tattgacttc aaaacgtgct tcttctccat
     2581 caaaggtcac atttttcccg acactagcca tagcacgata cttctgtctt tgaatctcaa
     2641 catcaacgac ataaacgcca tctgctggca tataagtacg gtctaaaagc actaaattcg
     2701 ctgtcggata accaattgta cgaccacgag cattaccatg aactaccata cctcttgatg
     2761 gaagcggtgc ccccaaaagt tttcctgctt ctttcacatt tccatctaaa atagcttgac
     2821 ggatacgagt tgaactaatc tttcctttct catcttctac aggtggaaca atgataactt
     2881 ctccatcaaa gtaatccttt aaatcttctg ctgttttttt gtcagaacca aatgtataat
     2941 caaaacctgc aacaataatt ttggcattca tagccttgat ataagttgca aagaattctt
     3001 gtgcagtgag actagcgaat tgactactaa aatcaaggag atataattct tctacacctt
     3061 cgcgctttaa ttttctttca cgttcagcag ggttcaaaat atgcaaaaac aaatctggat
     3121 gataaggctc taaagcgatc tttggagatt cattaaaggt cataacgacg ataggcaata
     3181 aatcctttct cgcagccttg ttggcaacac gaaataattc ttgatgcccc ttatgtatgc
     3241 catcaaaata gccgagaaca acgactgaat cagatggtgt gccaatatct ttttggtttt
     3301 ttataggaat agtaataatc ataaaataat tatatcatag cgatagctat ttctggaaca
     3361 gaaaatctga aatgttgttt ttttcacatg aagtgtacct gttttcaaaa agcactttat
     3421 tctatcgttg cttaactatg aactttgcaa tattcttctc aaaaacttgt aggacatctt
     3481 caaaattttg caaggagtga ttagacttgt tcggtaacta taaagtgtca tactatgctt
     3541 atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat tggtgccgaa
     3601 aaggtagaat ttagaataga ggtacaccta tggctgtaaa atttacaaaa tgagacaact
     3661 tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc actttccctg
     3721 atgacaaaga aaaaagccaa agcaataaag aaaaactaga tgactgcttt ccaacaactc
     3781 ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt ggattctcag
     3841 accgtttcag ctaaagaata tcttttcctt tatcagaagg aacggctcaa gccattcaga
     3901 caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat agtcaattga
     3961 aataaaatct gaagaaatcg agtaggaaac tcaaatcaat ttttagcagt gttctattcc
     4021 agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag gctgtacttg
     4081 agtacggcaa ggtgaaactg acgtggtttg aatttgattt tcgaagagta tcaatccact
     4141 atacatatta aaaagtatgg gtatcaaaat aaaaaaacag gctctccgaa aactcggaaa
     4201 gccttatttt aagctgtttc tagtttcctc acctttacat ttcaaggttc gggataaaag
     4261 gttcaatgga cctttttatt tagcgattgg gtaaacagaa acttgttttt tatcgcgtcc
     4321 tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt ctccaccacg
     4381 accaacgttt acacctggat agatgtgtgt accacgttga cggtaaagga ttgatccacc
     4441 tgttacagtt tgtccgtcag ctgctttagc tccaagacgt tttgcttgtg aatcacgtcc
     4501 gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt taagagtcat
     4561 ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt tggacgaact
     4621 cagaagagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag aataactggg
     4681 tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga tagccacctt
     4741 catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata gaattgataa
     4801 agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat tcgccactct
     4861 cggcgtgtcc agtaatttcc gcactcctca gctcgccatc ttcggctctc tcaaagactg
     4921 cctgtatcat gtgttctcct taaaattaag cgttgattgc gttgatgaca acttttgtat
     4981 atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac ttgtaagtaa
     5041 ccactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct ccagcaacaa
     5101 gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta aaagtaactt
     5161 cttgaccagc ttcaacgttc aatttttcaa cgtaaactgc ttgaccaact tcaactttaa
     5221 cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc ctatgatttt
     5281 tatgggtttc cccgattttt tgtgaagact cgcctagcat cgtgggacga accacttaaa
     5341 cttgaataat caagcaacga tgttcgtgcg gttgcacagg atcgtgcata gtcaactctt
     5401 caagtatagc atatctccta ttttcttaca agtaataaca cctaaaatca agctttttct
     5461 tttacttttt tctgccaaga ggcaaaaagc atgctgaggt aaaaaacgct catcataata
     5521 ggaacaccaa gaatggtctt ttcatgatag aaaatcgtca aataggctga aaagacaacg
     5581 ccaaggacaa aactactaag caggctaaca aatatgaatc cttcacgcaa aaaaggagtg
     5641 tgcttggttc ggaaataatc tccaaaagcc agcatggtcc gtttgatatt ccctgtcata
     5701 aaagcgttat tataggcaat acccgacact tctccaaaag cagttgtcac cagtcccata
     5761 cagaaggcca agggcggcac tagatagata ttatccacag tttgcggcac aaaagcaata
     5821 atgattgata agattgccaa gggaatcaag gacagaatag gttttttcac aattctcaat
     5881 ttttccttat aaatcgttaa taaaaagact cccattataa acgctattaa ggttaaaagc
     5941 ttatccctaa catccgaaac attattttgt attagctcta ccgaaagaaa gacaacattt
     6001 ccagcttgtc cagctacaag ggtattccct cgaacaataa aagtgtaagc atccacatat
     6061 ccagcacaaa acgtcaaaaa agtgctaacc ttttagactg acgtgatatt tttcttatag
     6121 gtaataacct cattttccct cccattgtat tttctcttag aaatattgta ccatttcttt
     6181 ctaaaaaatc gtaggctacc atttagattt tactattagc ataaaaataa taatagacaa
     6241 ctatttatcc aaaaatagat agaggtaaca tgtttgcaaa caaagcatac gaacctttag
     6301 taaaatcatt tccatgaaac tagaatagag cccctcttag caaaaatcat tattttaatt
     6361 tatttctaat cactccttga cataaataac tctcaccaat aaaagactat gtcttaaaaa
     6421 aatggtataa taaaatcaat acttgggctt gatggctatg ctactaataa caattaggag
     6481 agaaaatcag gcacttgtta acaacaagga ttatcccctt gagatgaaag gaactttaga
     6541 aatcttatga tgaacatgca aaacatgatg cgtcaagcac aaaaacttca aaaacaaatg
     6601 gaacaaagcc aagctgaact tgctgctatg caatttgttg gcaaatctgc tcaagatctt
     6661 gtccaagcga ccttaactgg agataagaaa gttatcagca ttgatttcaa tccagctgtc
     6721 attgacccag aagaccttga aactctttct gatatgaccg ttcaagccat caactctgct
     6781 cttgaacaaa tcgatgaaac taccaagaaa aaactgggtg ctttcgctgg gaaattacct
     6841 ttctaaaaac aaggagctag aacaatactt gtcgataaca aaggctaaga aaggtgcaaa
     6901 aattataaaa aacgcataat agcaggtgtc aaagcactca atattatgcg ttttctcatg
     6961 aaaaattctc ttttcatact catttaaaat caaaaaggga atttatcgtt ttacggacat
     7021 gtatattaca gatttctata ggtcgtgtat agacaggata tcatcgcatg gaagttttcc
     7081 tttttgacac caatcagtaa tttagttctc aggaattaat ggcagtgctt ttcgtacata
     7141 gtttcataac tacagtatag catagtatat cactttatag ttttcactat tgatgaactg
     7201 cttgagctgc tgtgatgagg gtcaacttgt aaacatcgtc tgcattacat ccacgagaaa
     7261 ggtcgttaac tggtttgttc aaaccttgca aaacaggtcc tacagccgca aaaccaccaa
     7321 gacgttcagc catcttgtaa ccaatatttc ctgcctcgat acctgggaag atgaagacat
     7381 ttgcttgacc agctaccgta cttccaggag ctttcagagc tgcagtttca ggaacaaagg
     7441 ctgcatcaaa ttgcaactca ccatcgattt caaggtcagg acgcaagtcg tgagcaattt
     7501 tagttgcttc aacgacctta tcaacgcttt caccaaaccc tgaaccttta gtagaatagc
     7561 tcaacatggc aattttaggt tcgatgccaa acatcttagc tgtgattgct gagttgatgg
     7621 caatttcagc caaggcttct gcatctggat tgatattaat ggcacagtct ccaaataggt
     7681 aacgttccgt accacgaacc atgaggaagg ctcctgaagt acgagttaca tttggacgag
     7741 ttttgatgat ttgtagagct gggcgaactg ttgaagctgt tgagtgaatc gctcctgaca
     7801 ccattccatc aaccaagccc aagtaaacca acatcacacc aaagtagttg acatcttcaa
     7861 ccaaaacctt gcgtacatct tcttcagtca ttttgccctt gcgacgctcc accaaggcag
     7921 aaaccatttc ttcaaattga ggataatgtt gagggtcgat gacctcataa ccatccatga
     7981 ttccttcaat ttcaagataa attttaattt tttcaggatt tccaagcaaa acaggaatca
     8041 cttctgtttc ttttactaag cgttttgttg cttgaagaat acgaggctct tccccttcag
     8101 ggagaacgat acgagcattt ttaccaacaa ggttggcttt gagactttca aaaacttcca
     8161 tgagttttct cctttaagat aataattata ctctgagaca gtttttatag agtattagtt
     8221 gataactggg taataaggtt actgaaatca tccggcaagg gactttctaa ctgcaagtct
     8281 tgctctaaaa atggatgata aaaggatagg taatggcaat gcagagcctg acgttgaata
     8341 ccatcttcca gactaccacc atacaaatca tctcccagca aaggaaaacc gatatgagaa
     8401 aaatggactc ggatttgatg ggttcgacca gtgtgcaggt gaatatagac caagtgaata
     8461 tttccataag aagctacaat cttgtatgaa gtatgggcat actttccgcc tttagccact
     8521 cgtctggtaa taatggaatc ttcatcacgc gcaatcggag caataatttc cccttctggc
     8581 tccaaatgtc catctccctt aaccaaagca aagtagcgtt tctcgataga tttcttctgc
     8641 aactgcttgt ctaatcgtgc atgggcataa ccgtgcttgg caaagatcat caagccagaa
     8701 gtgtccctat ctagtctggt aacaatgtga acctgctgat tttcataatt ttgcttgaca
     8761 tagtaaccct tgataaaatt ggcaatggta ttagagtgat tgacactagg aatagaagcc
     8821 actccatagg gtttattcaa gactagaaag tggtcatcct catagagaat atctaatgga
     8881 agctcaatag cctccaaggt ttcaaagcct ttctcagcgg gaatgtcaat ggtaacgtag
     8941 tctccaacgt ccaatagata cgttgcattt tgcggttgat tattgaccag aatagctcca
     9001 cctcgaaact taatcttagc cagcaatccc ttagaaacct cgtgcttttt taaaaaggtc
     9061 ttaaccttga catgttcatc tgcgataaat tcaaacctca ttcatccacc tcaccgataa
     9121 aggcatcctt aacacggttc cagaaactgg tatggctagg agtcgcgaca aagtgaatct
     9181 tatgatggtc gatttgatac tcaatacgct caatattacg gaaagaataa acgctattgt
     9241 caaccgaaat agtatgataa tcgtttcttg ttggaataag ttcaatctta tccttcttag
     9301 gcacaataat ggaagagccc agtgttcgat aaacacgatt attaaggctg gcaatttccg
     9361 ttaattgcaa agcttcaatg gtagggtgta aaacagcacc gccaagagac ttgttatagg
     9421 cagtactacc agtcggtgtc gaaactgtta gcccgtctcc acgaaaacgt tcaaagggaa
     9481 caccatttat tacaatatct gccaccatgg ttcgatcaga cctgcggatg ctggcttcgt
     9541 tgagtgctct gaaaatctta acttcaccat tttcaagaaa gaccttcaca ttcagaacag
     9601 ggtaagaaac ccttgcccca gtatctagct gcaaattagt cactagcttg tccaactcaa
     9661 aatcacgata atctgtatag aagcccaaat gtccagtatg aagaccgata aagcggacct
     9721 tgtcaagctg attttcgtac ttatgaaagg ccgacaagag cataccatcc ccgccaatgg
     9781 aaatgacaat atccggattg gtatcattga gtataaactg atttctcttc aaacgatctc
     9841 gcaattcata caaaaccctt tgactctgcg gttttctatt ggctatcaga tcaattcgtt
     9901 tacctgtatt cttcatctgt atcgtcactg tttcctacac cgtcatttaa ttttctactc
     9961 aaaggatcaa aaagtgcctg ggcttcttgg atatcatcac gaatttcacc catttcttca
    10021 tccaactgat gagcgattct agctgtaatt tccagtcgct tcttaatctc atctgggaaa
    10081 tccccttggt acttgtagtt gagagaatgt tctatcgttg cccagaaatt catggccaaa
    10141 gtacgaattt gaatttctgc caaaatagtc ttagctccat tgatggtatc aaccgtatat
    10201 tctactacca catgatagga acgatagcct gatgcttttc tatgagtaat gtaatctcgc
    10261 tcctgtatga ttcgcatatc ctgacgcttg tgcaaaatat ccactacttc cttgacgtca
    10321 tctacaaact gaaccatcac acgtaagcca gcaatatcct gcaaatcgtg ttccaaggtc
    10381 gcataagtaa tgccacgacg agccattttt tctttgatgc tctcaattgg cttgactcga
    10441 ccggtcacaa actcaattgg agaatgctta ttttgcttac gatattgctt acgaatacca
    10501 cgaagtttaa tctttaactc accaacagct tgaatgtaag gatctagaaa ttcttcccat
    10561 tctaaggtca tatattctcc cttgttctca tattatccgt caaaaatatc tttgattttt
    10621 tctccagatt catatacaat aaatacaatg cttattatac cataaatccg ctttcaacga
    10681 taaaaaaagg taagaaaaat gaaacattta gaaattgaat tgaaaacact attgaaaaaa
    10741 gatgaataca atcgtctaaa agaccagttc acaggtgtca ctcctgttct tcaaacaaat
    10801 tactacatag acacgcctga ttttgaactg cgagaaaaga aagtcgctat gcgcattcga
    10861 acctttgaag actgggctga gttgacactc aaagtcccgc agagtgttgg aaacatggaa
    10921 tacaaccaaa aattgcaact aaaagatgct gagaactatc tgagtaagga agaacttcct
    10981 caagggctag tactggatga attggcgaaa catggtatcc aaagtaagaa ctggcaggtt
    11041 cttggttgtc taacaacgct tcgctatgaa atgaaaacag ctattggtct catggcactg
    11101 gatcagagcc gatactttga tatgacagat tacgaattgg agcttgaagt ggaaaatcat
    11161 gagcaaggca aacaggattt ccgacaattt ttagagaaaa atcagatttc ctaccaaaaa
    11221 gctccttcaa aattggttcg atttgtcaaa agtatgaaaa atagctgaaa taatctccat
    11281 tttttggtaa aatagaaaag ataaaaatac acaaatccca gttcatatat gtaaggtaaa
    11341 tataactagg atttataaag tttacagagg acggtctata atgtcagata gaaaaaacat
    11401 gaaacttttc gcactcaact ctaaccaaga gattgcacaa aaaattgccc aagctgttgg
    11461 tgtcccactt ggaaaactat catcacgtca attttcagac ggagaaatcc aagtaaatat
    11521 cgaagaaagt gtccgtggtt atgatgttta catcatccaa tcaacaagtt tccctgtcaa
    11581 caaccaccta atggaattgt taatcatggt cgatgcttgt gtgcgtgcaa gtgcccacag
    11641 tatcaacgtt gtccttccat attttggcta tgcacgtcaa gaccgcattg cttgtcctcg
    11701 tgagccactt acagcaaaac tagttgccaa tatgctggtt aaggctggag ttgatcgtat
    11761 cctgactctt gatttgcatg ccgttcaggt tcaaggtttc tttgatattc cagtggataa
    11821 tcttttcact gttcccctat tcgcaaaaca ttactgcgat aaaggattgc ttggttcaga
    11881 tgttgttgtc gttagcccta aaaattcagg tgtcaaacgt gcgcgtagcc tggctgaata
    11941 tcttgatgct cctatcgcca ttatcgacta ccctcaagac gatgcaactc gtaacgaagg
    12001 ttatattatt ggtgatgttg aaggtaagaa agctatcttg attgatgata ttttaaatac
    12061 aggacgtacc ttctctgaag cttctaaaat cgttgaacgt gaaggagcta cagaaattta
    12121 tgctgtttct agccacggtc tcttcgtcga gggagctgct gagcttcttg acaatactaa
    12181 tattaaagaa attcttgtga ctgattcagt agcaacaaaa gaaaaaactc ctaaaaatgt
    12241 atgctacatc actgctagtg agttaattgg tgatgctatc gtccgtattc acgaaagaaa
    12301 accagtcagc ccgctctttg cctacaataa aaagaaataa ggtgattctt tgatttattt
    12361 ggacaatgct gcaacgactc ctatgtcagc agttgctatt tcagctatga ccaaggttat
    12421 gcaagaaacc cacggaaatc cttctagtat tcatggtcat ggtcgtcaag ctggcaaact
    12481 cttgcgcgaa gcccgtcagg aactagccca gttattaagg acaaaacctc aacatatctt
    12541 tttcacttct ggtgggactg aaggcaataa tactaccatc attggctact gtcttcgtca
    12601 ccaagaacaa ggaaaacata tcatcacaac tgccatcgag caccatgctg tccttaaaac
    12661 aattgattac ttggttcaac actttgggtt tgaagcaacc attatccagc cagaaaatca
    12721 agaaatcaca gcccagcaaa ttcaaaaggc tttacgtgac gatacgattt tggtttctac
    12781 catgtttgcc aataatgaga caggaaacct actgcccatc gctgaaattg gccaaatact
    12841 caagcaacac cctgctgcct atcatgttga tgcagttcag gctattggta aaatcccaat
    12901 tcattcagaa gaattgggca ttgattttct cactgcttct gcccacaaat tccatggtcc
    12961 taagggaatc ggttttctct acgcatctag catggacttt gattcctatc tacatggcgg
    13021 agatcaggaa cagaaaaaac gtgcaggaac tgaaaatctg cctgccatcg taggcatggt
    13081 tgcagcccta aaagaagacc tagaaaaaca agaagaacat tttcaacatg tacaaaatct
    13141 agaaactgcc tttctggcag agctggaggg cattcagtat tacttgaata gaggaaaaca
    13201 tcatctccct tatgttctca atattggatt tcctggtcag aaaaatgacc tcttactcct
    13261 tcggctagat ttagctggaa tttcaatctc tactggctca gcctgtactg caggcgttgt
    13321 ccaatccagc catgttcttg aagccatgta tggcgcaaat tcagaacgct tgaaggaatc
    13381 ccttcgcatc agtttgtctc cacaaaatac cgttgaagac ctacaaaccc tcgcaaaaac
    13441 cttaaaagaa attatcggag gttagccata tggcatttga aaaaatcatt cagttaaaaa
    13501 attgtcgtta cgattacact cttagccctt ctgttaaaaa attcaccctc aaagataaca
    13561 ccttttttga aactaaggtt ggtaactatg aactgactcg ccttttggaa aaagtgccaa
    13621 acagcggtga aggcttccaa ctcaaaatca tcattaacaa ggaacttaca ggggctaaaa
    13681 tcaatatcac tgacaagttt ggccttcgtc tagttgatat tttcaaatca gaagaccacc
    13741 atattcatca ggaaaaattc tacttcctca tggatagctt ggtagaacgt ggtgtcttta
    13801 caaaatcgga aagatagagc caaaatgttt gaactgacct ataaggactg ctatcatgta
    13861 gagcgtactc tcaagtatga ggatcatgag gctctcatgt tgactttgtc aggatgtgta
    13921 accttaccag atacacttta tgtgacttct ctgactttta ggggccaaaa agtttatcag
    13981 ggtctggtcg gagacctcta ccgttttcta tctcatgcag attttttaca tcaaaactaa
    14041 gatttttctt agttttttct tatttttgtt gattttttca caatgtttct ataaaataga
    14101 agaatagaaa ggttgtgatt ttgtgaaaga taaacaattt gctattccaa aagctacagc
    14161 aaaaagactc tctctctact atcgaatttt taagagattt catgcagaaa agattgaacg
    14221 tgccaactct aagcaaattg cagaggccat tgggattgat tcagcgaccg tacgtcgtga
    14281 tttttcctat tttggtgaac ttggtcgtcg tggttttggc tatgatgtca aaaaactaat
    14341 gacatttttt gccgatttgc tcaatgacaa ctctattacc aatgtcatgc tggttggtat
    14401 tggaaatatg ggccatgccc ttctccacta ccgcttccac gaacgtaaca agatgaagat
    14461 tatcatggcc tttgacctag acgaccatcc tgaagtcggt acccaaactc ctgacgggat
    14521 tcccatttac gggatttctc agatcaagga taaaatcaag gatgctgatg tgaagactgc
    14581 tatcctaact gttcccagcg tcaagtcaca agaggttgct aatctcttgg ttgatgctgg
    14641 tgtgaaagga attctcagtt tttcaccagt ccatctgcat ttaccaaaag acgtggtcgt
    14701 tcagtatgtc gatttgacaa gtgaactcca aaccctcctc tacttcatgc gaaaagagga
    14761 ttagaaagcg aaaatcattt tatgaaaaaa ccagttattg ggattacagg aaacgaaaaa
    14821 actcatccag atgatgacat catgatgagc tacgcagcaa aaggctttgt tgaaggcgtt
    14881 aaagatgctg gagggattcc catcatccta ccgattggtg atcaagaaat ggcctgccac
    14941 tatatcagtt tgattgacaa gctcatcttg acaggtgggc aaaatgtcga tccaaaattc
    15001 tatggcgaac ccaaaaccat tgatagcgat gattatcacc ttcaaagaga tatcttcgaa
    15061 ctggccctca tcaaggaagc tattaaacag aaaaagccca ttttctctgt ctgccgtggt
    15121 acccaactct ttaacgttgc catgggtgga actttgtacc aagatatcga agaccattgg
    15181 caggattctt ctgttgagta cacaactcaa cgcttggtaa cagaaccaga taccgttctc
    15241 caagaaatct atggagaaat ctctcatatc aactccttcc accaccagag catcaaggac
    15301 ttagcaccaa atttaaaagt tgtggctcat gatcctaaag atggtatcat tgaggctgtc
    15361 atgagtacgg atgatgtcgc ctttctcggt gtccaatggc atccagaact tctttttgaa
    15421 aatcgtccca aagataaaaa actctttgac tatgtcgtta atgaacttta gattaaatct
    15481 gtcttttcac gataactaaa gtaattagaa tgagagacaa tcaaatggtc caagagaaca
    15541 atccccatca gttcgcaggc ttctttaaca agtttagtga catgatcatc attttggcta
    15601 ggcgctaccg ctcctgaagg atgattgtgg accaagataa gagaagtcgc catatgcttg
    15661 attgcatagt gaagaatctc tcgcggttca gcgatactac gagttacaga accgataaaa
    15721 atggtctgct gatggatgat ttgattttga gtattgagat agagtgccac caggtgctct
    15781 tgttttttat cccctaattc ctgctgcatc ttcttggcca acttttgact gctgagaata
    15841 ctttccattt caagagtctc gtgtttgtga atacgatgcc ccagttcaat catagcttgt
    15901 aattctatgg ccttaacacg cccaatacca gacaaactct gcaattcctg cagggtcatt
    15961 tttttcaaat ccgttaggct tgaaagattg ttcaagactt tttgggcaat ttcaaaaacg
    16021 ctaacttgac gtgttcctgt cctgagtaaa atagctagca actcttggtt actaagcgct
    16081 tcaactcctt ccttggccag cctttctctt ggtaatagtg aatcttcttg gaatgaaata
    16141 ctgtacataa aaatcctcct cactttatta ttcgtgagaa ggatggaaaa ttagattttt
    16201 ttctcaattg gagccacact ggctaaaagt tttttcaaac ctacttctgg gaaattgatt
    16261 ttcaattcct gcctagcacc gctacctgaa acttccagaa cggttccctc tccccatttc
    16321 ttgtggagag caatatcacc aatggaccaa tttgcctcgc tagatgctgg ttttgcgcca
    16381 gctgtaaatt gaccaaatgg aagaccgctt gactggattg attttggggc agcaccgcgt
    16441 ttacggtttt gaagagcctg agccaaactc ataccttgac caaaggaaat actaccactg
    16501 ctatatgatg ccttaaagct tgtatttgca ggacgagcca gaccttgata ctcaagcaag
    16561 tctgaactga tttcgttaat aaaacgagtc ggacggttat aattggtacg accaaaaagc
    16621 aagcgtgagt tggcattggt cagatagaga attttctctg cacgcgtgat acctacatag
    16681 gctagacggc gctcttcttc taattcatct ggatcttcag tcgcacgact aagtggaaag
    16741 acattttctt ccatcccaat caaaaagaca actggaaatt cgagaccttt ggcagcatgc
    16801 agggtcatca aggtcacttc tgatgtctcc tgactacctg aatctgtgtc agcaatcaaa
    16861 gccaagtcat ttaagaaacg actcagtttg tccagaccag tttcctcttc tgtcacatcc
    16921 gtggtgtcat caaagttctt cgtaacagaa agaaactctt cgatattttc aacccgtgcc
    16981 ttgctttcta gagtcgcttg ggcgttaaga atatcgacat aacctgtttt ttctaggacg
    17041 gactcaacca actctgtaat gcttaagtgg tctagctgct cccgcaaatc aagcatcata
    17101 ttggcaaaat cccagataga ttgggctgcc ttacccttga taccagacaa cataatatta
    17161 gcagaagcat ccagcataga catattttgc aaatttgcaa aatcacggat tttctcaact
    17221 gtacctagac caattccacg tttaggctcg ttgataatac gctcaaaact aatattgtca
    17281 ctcaaattag caataaggtt gagataagca ataatatcgc gaatttcctt acggctgtag
    17341 aatttggttc cgccaaccat ggtataagga atgttagact tgagcagggc ttcctcaatt
    17401 gtacgggact gggcattagt ccgatagaga actgcaaaat ccttatgaag gaagttttga
    17461 ctgcgactaa gttcatcgat ggttctggct acaaatacag cctcatccag ctcatcatcg
    17521 gcacgatagt aaacgatttg ctccccatca gcgttttgag tccagagatt tttaggacgg
    17581 cgatttttat tatttttaat aacctcgttg gccgcttgga gaatggtttt ggttgagcgg
    17641 taattttcct ccaacaaaac aaccttggct ttggggtaat ccttttcaaa gtccaagata
    17701 ttctgcatat cagcaccacg ccaaccgtag atagactggt ccgcatcccc aaccacacag
    17761 atatttttaa aacgggaagc caagagtttg accaattggt actgagcgtg gttggtatct
    17821 tggtactcat caacgtggat gtattggaat ttttgctggt agtaggtcaa aacatcagga
    17881 ttttgatcaa agagacgcaa ggtcagcata atcaaatcat caaagtcaac ggattcggac
    17941 tgacgaagtt ctttttgata ggctgtataa cactgggcca caatttgcgt atacatatcg
    18001 ccagcttggg caacataagc aacatcatca atcaaatcat tcttagcatt ggaaatggtc
    18061 cccaaaatag ttcgttcatt ccatttttta ggatccaagt tcaactgttt tagaatacgt
    18121 ttcatgagcg ttcgctgttc accaggatcc acaattgtaa aattacgatt gtagccaata
    18181 tggtccgcat ctcgacgcaa aatacgcaca cacatggagt ggaaggtcgc aatcagacag
    18241 tcctgagtag ctggattgag gctataagca cgctctttca tctcacgcgc agccttgttg
    18301 gtaaaggtaa tggccaagat attccaagga ttgaccagct tttcatcaat caaataagcg
    18361 atacggtggg ttaaaacacg agtctttcca gaaccagccc ctgccatgat tagcaaggga
    18421 ccttctgtcg tttgcaccgc ctcagcctga cggtcattca ttccatttaa taatgcgttc
    18481 atcttctctt ccttactctt gaagtcaata tttctattat atcagaaatc agggaaaata
    18541 gaaactttac ggggagtagc aaaatatagt ggattgaaac tagaatacta cactgtgggt
    18601 ttctaaaaca ctcgactttt cacccaattt tttcataaac tagctcaata cctcaataga
    18661 cttcctgcaa aactagaatc ctagttcatg attgataata ccagcaatca aattcattcg
    18721 taatccgaag cgtttacgat gatttcgata ggttgttgaa aacattttaa acgtttttac
    18781 tttggcaaag atgttctcaa ccttgcttct ttccttagat agcgcatggt tataggcttt
    18841 atcttcagct attagcgact tgagtttgct ggatttacgt ggagtttgta cttgaggata
    18901 tatcttcatg agcccttgat aaccactgtc agccaagatt ttaccagctt gtccgatatt
    18961 tctgcaactc attttgaaca acttcatatc acgacaatag ttcacagtga tatccaaaga
    19021 aacaattctc ccttgacttg tgacaatcgc ttgagccttc atagcgtggc atttcttttt
    19081 accagaatca ttcgctaatt ctttttttag ggcgattgat t
//
LOCUS       DAVMAH010000044        18766 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVMAH010000044 DAVMAH010000000
VERSION     DAVMAH010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18766
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.044"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            16..525
                     /locus_tag="VYO94_001522"
     CDS             16..525
                     /locus_tag="VYO94_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760141.1"
                     /translation="MGQIYYGLSNFPDIVILDKTYENKSRKSIKIEEWKKLRGCVEVK
                     NLNYSLITEEKIKSTISNSFEHITGEMEQLTGEMGQLIGDLLWYKKVIYTNGIEWRFL
                     SLDDKEEIDNTIVEVVNKRIETEEAGNSFDWWKNIKDLSFNYTDICLSKDCRQEWNEF
                     VKRVKEIEW"
     gene            564..665
                     /locus_tag="VYO94_001523"
                     /pseudo
     CDS             564..665
                     /locus_tag="VYO94_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(716..922)
                     /locus_tag="VYO94_001524"
     CDS             complement(716..922)
                     /locus_tag="VYO94_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV1760142.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            974..1450
                     /locus_tag="VYO94_001525"
     CDS             974..1450
                     /locus_tag="VYO94_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV1760143.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            1459..2130
                     /locus_tag="VYO94_001526"
     CDS             1459..2130
                     /locus_tag="VYO94_001526"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV1760144.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            2261..2599
                     /locus_tag="VYO94_001527"
     CDS             2261..2599
                     /locus_tag="VYO94_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV1760145.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            2602..3231
                     /locus_tag="VYO94_001528"
     CDS             2602..3231
                     /locus_tag="VYO94_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV1760146.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            3471..4622
                     /locus_tag="VYO94_001529"
     CDS             3471..4622
                     /locus_tag="VYO94_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1760147.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            4935..5684
                     /gene="truA"
                     /locus_tag="VYO94_001530"
     CDS             4935..5684
                     /gene="truA"
                     /locus_tag="VYO94_001530"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV1760148.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            5674..6447
                     /locus_tag="VYO94_001531"
     CDS             5674..6447
                     /locus_tag="VYO94_001531"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1760149.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            6425..6886
                     /locus_tag="VYO94_001532"
     CDS             6425..6886
                     /locus_tag="VYO94_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1760150.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            7114..8462
                     /locus_tag="VYO94_001533"
                     /pseudo
     CDS             7114..8462
                     /locus_tag="VYO94_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(8591..8794)
                     /locus_tag="VYO94_001534"
     CDS             complement(8591..8794)
                     /locus_tag="VYO94_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760151.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(8787..9869)
                     /locus_tag="VYO94_001535"
     CDS             complement(8787..9869)
                     /locus_tag="VYO94_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1760152.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(9995..10777)
                     /locus_tag="VYO94_001536"
     CDS             complement(9995..10777)
                     /locus_tag="VYO94_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV1760153.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(10777..12120)
                     /locus_tag="VYO94_001537"
     CDS             complement(10777..12120)
                     /locus_tag="VYO94_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV1760154.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGVDSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(12219..13535)
                     /locus_tag="VYO94_001538"
     CDS             complement(12219..13535)
                     /locus_tag="VYO94_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV1760155.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVISTKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGNYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            13728..14954
                     /locus_tag="VYO94_001539"
     CDS             13728..14954
                     /locus_tag="VYO94_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV1760156.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            15153..16727
                     /locus_tag="VYO94_001540"
     CDS             15153..16727
                     /locus_tag="VYO94_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1760157.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            16992..17780
                     /gene="codY"
                     /locus_tag="VYO94_001541"
     CDS             16992..17780
                     /gene="codY"
                     /locus_tag="VYO94_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV1760158.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            17780..18355
                     /locus_tag="VYO94_001542"
     CDS             17780..18355
                     /locus_tag="VYO94_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1760159.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            18438..18523
                     /locus_tag="VYO94_001543"
     tRNA            18438..18523
                     /locus_tag="VYO94_001543"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18472..18474,aa:Leu,seq:aag)
BASE COUNT         5594 a         3414 c         4122 g         5636 t
ORIGIN      
        1 agacaaagaa ggggtttggg acaaatttat tatggtctaa gtaattttcc tgatatagtt
       61 attttagata agacttatga aaacaaatct aggaaaagta taaaaattga agaatggaag
      121 aaacttcgag gatgcgtgga agttaagaat ttaaattata gtttaattac agaggaaaaa
      181 atcaaatcaa ccatatcgaa cagttttgaa catataactg gagagatgga acaactaact
      241 ggagagatgg gacaacttat tggagacctt ttatggtata aaaaagtaat ttatacaaat
      301 ggaattgaat ggagatttct aagtttagat gacaaggaag agatagataa tacaattgtt
      361 gaagtagtta acaaaagaat agaaacagaa gaagcgggaa attcttttga ttggtggaag
      421 aatattaaag atttatcgtt caattatacg gatatatgcc tatctaaaga ttgtagacaa
      481 gagtggaatg aatttgtaaa aagggtaaag gaaatagaat ggtagaagtc tattctcatt
      541 gagaaattta gattttaagt tacagtaaga tttatttaga gactaaaaaa agaccacttt
      601 atcttatcaa agaaaaaagt gaccttcctg attttacaga aaaaaataaa gtgaaaagac
      661 tataatttta catggaaatg tgctaaacta gagggagtgg attatcgcca ttgatttagg
      721 cttcctggtt tccaatcagg gcgcgagttg ggcaattttt aacagcctct aagacatcct
      781 gactaggaga aatttctttt tccagttggt cagggtcatc gtaaaaacgc acgattccat
      841 tatcgtggta atcaaataaa tcagaataag tttggcaaag cccacaggcg atacatcgtt
      901 caggtataag tgtgattttc atgttcatat ttatattgta ataagaaaag taaaaaaaaa
      961 caaggagtaa ggtatggcaa aagaaccgtg gcaagaagat atctatgatc aagaagaatc
     1021 aagagcagag cgtcggcatc gaaaccacgg aggggctgat aggatggcta atcgtatttt
     1081 gacgatccta gctagtattt tctttgtaat tgtggtggtg atggtcatcg ttctcatcta
     1141 tctatcatcg ggggggagta atcgcacagc agccttaaaa gactttcatg attctgatgc
     1201 aagtgtagta caaatctcat cttcaagcag ttctcagcct gagcagagtt cagagccaga
     1261 atctacttct agtagttcag aagaagctgc taatcctgaa ggaacgatta aagttctcgc
     1321 aggagaaggg gaagcagcta ttgccgctcg tgcaggaatc tccattgctc agttagaggc
     1381 cttgaatcct gggcacatgg ctacaggatc ttggtttgct aatccaggtg atgttataaa
     1441 aataaaatag gagccgatat gaaaacaatt caaattgcta ttgatggtcc tgcttccagc
     1501 ggtaagagta cggtcgcaaa gattattgct aaggattttg gattcaccta ccttgataca
     1561 ggagctatgt atcgtgcagc gacctatatg gctcttaaga accaattagg agttgaagaa
     1621 gtcgaagccc ttctagcctt gttggaccag catccaatca gctttggacg ttcagaaact
     1681 ggagaccagc ttgtttttgt aggagatgtg gatattaccc atcctatccg tgaaaatgaa
     1741 gtgaccaatc atgtttctgc tattgcagca attcctgaag tgcgtgagaa actggtttct
     1801 ctccaacaag aaattgccca gcaaggcggg attgtcatgg atggtcgcga tattggaact
     1861 gttgtattgc cacaagcaga attgaaaatt ttcctagtag cttctgttga tgagagagca
     1921 gagcgtcgtt acaaggaaaa tattgccaag ggaattgaaa cagaccttga aaccctaaaa
     1981 aaggaaattg ctgcgcgtga ctacaaggat agtcatcgtg agacttctcc tctcaaacaa
     2041 gcagaggatg ctgtctacct tgatacaact ggtttgaaca ttcaagaagt agttgaaaaa
     2101 atcaaagcag aagctgaaaa aagaatgtaa atgtagaaaa gccgatagat tgatatcggt
     2161 ttttttctaa atttgtcaaa atgctgattt tagggtataa tagttgctgt tcgagaaatt
     2221 ttgattttca aagaatagtg aatgatgata aggagaaacc atgaacaatt taccaaattg
     2281 tccaaaatgt aactcagagt atgtctacga agacggtgcc ctactggttt gcccagagtg
     2341 tgctcatgag tggaatcctg ctgaagttgc agaagtagaa gaaggtcttg tcgctatcga
     2401 tgccaacgga aataaattga ctgatggtga tacagtaact ctcatcaagg acttgaaagt
     2461 aaaaggtgcg ccaaaagatt tgaaacaagg gacgcgcgtg aaaaatatcc gcatcgtaga
     2521 aggcgaccac aatatcgact gtaagattga tggttttggt gccatgaaac ttaaatcaga
     2581 gtttgtgagg aagatttaag catgtcaaaa cactataaac ttgtatttta tagccgtatc
     2641 ttcttgtttc tagcggcttt tacgggagtt tatcttgaaa ttactaggca tggtggtttt
     2701 gggatgcttc tctattacac ggttctgtcc aacctcttgg taactatttt taccctttat
     2761 cttctaaagg ttatgagccg tgtaggtgaa aattggcaaa ggccaagtct cttgcgctta
     2821 aaaggtgggg tcaccatgag tatcatgatt acctgtgtga tttaccattt cctcttggcg
     2881 cccattgcga ctaatttcta taccctagaa aatttccttt gccactatat cgttcccatc
     2941 tggtttttag cggataccct cttttttgac aaacagggtc aatacaagat ttgggatcca
     3001 gcagtgtgga ccattttacc ctttctgtat atgatgtttg ctctttttaa tggcttggtt
     3061 ctaaaactca atattccaaa tgccaaggat aatcctttcc cttacttctt tttgaatgtg
     3121 aacaagggtt ggaatgttgt gtttaagtgg tgtctgatta tctttgttgc ctatatggta
     3181 gcaggattta ttttctactt tatcaagcaa atcaagagaa agtcatccta atactcttcg
     3241 aaaatctctt caaaccacgt tagtttccat ctgcaacctc aaaacactgt tttgaacaac
     3301 ctgcggctag ctttctagtt tgctctttga ttttcattga gtatgagata caagggattc
     3361 attttcgaat ttaagaagga gtctacaaac caatgaggct tcttcttttc ttgcttattt
     3421 gataactatc aaaaaagtag aagattaaga gaaatataga aagagatttc atgaaacaat
     3481 ttttagaacg ggccagcatt ttggctctct ccctcgtttt gattacctcc ttttccattt
     3541 cgagtgccct accagccatg tttgactatt atcagggtta ttctaaggaa caaattgagc
     3601 tcttggtgag cttgccttcc tttggaatca tgatgatgtt actgctaaat ggtttcttag
     3661 aaaaaatatt tcctgagcgc ttacagatta gtttgggctt gctgatttta tcattgagcg
     3721 gtacagctcc cttctggtac caagcctatc cctttgtctt tggaacacgg cttctctttg
     3781 gtttgggtct tgggatgatc aatgccaagg ccatttctat tatcagtgaa cgctaccaag
     3841 gaaaaaggcg aattcagatg ttagggctac gcgcttctgc agaggtcgtt ggagcttctc
     3901 tcattacctt ggccgtcggt cagttgttgg cctttggttg gacagctatc tttctagcct
     3961 atagtgctgg atttttggtg ctgccccttt atctgctctt tgtcccttat ggaaaatcaa
     4021 agaaagaagt caagaaaaga gcgaaggaag caagtcgttt aactcgagaa atgaaaggct
     4081 tgatttttac cttagctatc gaagcggcag ttgtagtttg taccaataca gctattacca
     4141 tccgtattcc aagtttgatg gtggaaagag gattggggga tgcccagtta tctagttttg
     4201 ttcttagtat catgcagttg atcgggattg tggctggggt gagtttttct ttcttgattt
     4261 ctatctttaa agagaaactg ctcctctggt ctggtattac ctttggcttg gggcaaatcg
     4321 tgattgcctt gtcttcatcc ttgtgggtgg tagtagcagg aagtgttctg gctggatttg
     4381 cctatagtgt agtcttgacg acggtctttc aacttgtctc tgaacgaatt ccagctaaac
     4441 tcctcaatca agcaacttca tttgctgtat taggctgtag tttcggagcc tttacgaccc
     4501 catttgttct aggtgcaatt ggcttactaa ctcacaatgg gatgttggtc tttagtatct
     4561 taggaggttg gttgattgta atctctatct ttgtcatgta cctacttcag aagagagctt
     4621 aggattgatt cctaagtttt tcttttgata ctcaatgaaa atcaaagagc atagttgatt
     4681 gagtttggaa tagtacgctg tagctgctaa aatatttcta gaaattaatt tgacttttct
     4741 aatagagtta ttcatatctt atttcaatct actatagaaa gctagccgca ggttgctcaa
     4801 aatagtgttt tgaggttgca gatggaaact gacgtggttt gaagagattt tcgaagagta
     4861 tgagattttt atacccatac aatatttgtt ttaggtcctt gtttacagac taatttcttg
     4921 ataaaataga ggttatgacg agatataaag caactatttc ctatgatggt tatgcctttg
     4981 ctggctttca gcgccagtct catgcgcgta gcgttcagga agaaattgaa aaaaccttga
     5041 ccagattaaa taaagggcaa accattactg ttcacggtgc tggtaggaca gatagtgggg
     5101 ttcatgccct gggacaggtc attcattttg acctgcctta tcagatggat gaggagaaac
     5161 tccgttttgc cttggatacc cagtctcctg aagatattga tgtgatttcg attgagcttg
     5221 tggcagatga ttttcattgc cgttatgcca aacatagcaa gacctatgag tttattgtgg
     5281 atagaggacg tcccaaaaat cctatgcgcc gtcactatgc cacccacttt ccctacccac
     5341 tcgatgtgga acgaatgcag attgcaatca aaaagctaga gggaacccat gattttaccg
     5401 gttttacagc ctctgggact agtgtagagg ataaggttcg caccatcaca gaagctagtt
     5461 taatagtcga tgagacagga caatttttga cctttacctt ttcaggaaat ggtttcttgt
     5521 ataaacagat tcgcaatatg gtggggactc ttctcaaaat cggtaacaac cgcatgccag
     5581 tagagcagat tgatctcatc ttggagaaga aggacaggca acttgcaggt cccactgcag
     5641 caccaaatgg tttgtattta aaggagattc gttatgaaga ataatcgtat tttagcactt
     5701 tctggaaatg atatttttag tggtggtgga ctgtcagctg atttggctac ctataccttg
     5761 aacggcttgc atgggtttgt agcagtgact tgtttgacag ccttgacaga aaaaggattt
     5821 gaagtctttc caactgatga taccattttt caacatgaat tagatagctt gcgtgatgtg
     5881 gaatttgggg gaattaagat tggtcttctc cctactgtca gtgtggctga gaaggccttg
     5941 gactttatca aacaacgccc aggagtacct gtggtgttgg atcctgtctt ggtctgcaag
     6001 gaaacgcatg atgtagctgt cagtgagctc tgccaagagt tgattcgctt tttcccttat
     6061 gtcagtgtga ttacgcctaa tctcccagaa gcagaattat tatccggtca ggaaattaaa
     6121 accttggaag acatgaaaac tgcagcgcag aaattgcatg atttaggagc gccagcagtc
     6181 attatcaagg gaggcaatcg tcttagtcag gacaaggctg tggatgtctt ttatgatgga
     6241 cagaccttta ctatcctaga aaatccagtt atccaaggcc aaaatgctgg tgcaggttgt
     6301 acctttgcct ctagcattgc cagtcacttg attaaaggtg ataaactttt gccagcagta
     6361 gaaagctcta aggctttcgt ttatcgtgct attgcacaag cagatcagta tggagtaaga
     6421 caatatgaag caaacaaaaa caactaaaat cgcccttgta tccctattaa ccgccctttc
     6481 tgtggttcta ggttatttct taaaaatccc aacacctaca ggaattctaa ctcttttaga
     6541 tgctggtgtc ttctttgcgg ccttttactt tggtagtcgt gaaggagcgg tagtcggagg
     6601 actagcaagt ttcttgattg acctcttatc aggctaccct cagtggatgt tctttagctt
     6661 ggtcaaccat ggcttgcagg gatttttcgc aggatttaaa ggaaaaagtc agtggttagg
     6721 ccttatttta gcaactattg ccatggtagg aggctacgcc ttgggttcta ctttgatgaa
     6781 tggctgggca gcagccctcc cagaaattct accaaatttc atgcaaaata tggtagggat
     6841 gattgtagga tttattctta gtcaaagtat caagaagatt aagtaatact tttcgaaaat
     6901 ctcttcaaac cacgtcagct tccatctgca acctcaaaac actgttttga gcagcctgag
     6961 gctagctttc tagtttgcac tttgattttc attgagtata aagaggttga gtaaaaagta
     7021 tttcaaataa gaaaaacgca tagtatcagg tgttgaatga actgcccccc aaaagttaga
     7081 cagaaaaaat ctaacttttg gggtgttttt attatgaaac taacttatga tgataaagtt
     7141 cagatctatg aacttagaaa acaaggatat agcttagaga agctttcaaa taaatttggg
     7201 ataaacaatt ctaatattag gtacatgatt aaattgattg atcgttacgg aatagagttc
     7261 gtcaaaaaag gaaaaaatcg ttactatttt cctgatttaa aacaagaaat gattcataaa
     7321 gtcttacatg aaggctgaac taaagataga gtttctcttg aatacggcct cccaagtcgt
     7381 acgatacttc ttaattggct agcacaatac aagaaaaacg ggtatactat tgttgagaaa
     7441 acaagagaga gagtacctaa aatggggcgt aagccacaaa agagacctga agagaggaca
     7501 gaattagaac gtcttcaagc agaaaatgag tacctgagag cggagaatgc tatcctaaaa
     7561 aagttaagag aactccgatt gaaggaggaa aaagagaaag aagaaagaca gaaattgttc
     7621 aagaattaat gactgagttt tcgttagata ttcttctaaa agccattaaa ctagctcgtt
     7681 ggacctacta ctatcacttg aaacagctag acaaaccaga taaggaccaa gagcttaaag
     7741 ctgaaattca atccattttt atcgaacaca agggaaatta tgcttatcgc cgggttcatt
     7801 tagaactaag aaatcgtgct tatctggtaa atcataaaag agttcaaggc ttgataaaag
     7861 tactcaattt acaagctaaa atgcgacaga aacgaaaata ttcttctcat aaaggagacg
     7921 ttggtaagaa agcagagaat ctcattcaag gccaatttga aggctctaaa acaatggaaa
     7981 agtgctacac agatgtgaca gaatttgcca ttccagcaag tactcaaaag ctttacttat
     8041 caccagtttt agatggcttt aatatcgaaa ttatcgccta taatctttca acttcatcca
     8101 acttagaata agtacaaaca atgttggaac aggcattcac agagaagcac tacgagaata
     8161 cgattctcca tagtgaccaa ggctggcaat accaacacga ttcttatcat cggttcttag
     8221 agggtaaggg aattcaagca tccatgtcac gtaagggaaa cagccaagac aacggtatga
     8281 tggagtcctt ctttgggatt ctgaaatcgg aaatgtttta tggctatgag aaaacattta
     8341 aatcacttaa tcaattggaa caagccatta tagactatat tgattactac aacaataaac
     8401 gaattaaggt aaaactaaaa ggacttagcc ttgtgcaata cagaactaaa tcctttggat
     8461 aaattatttg tctaactttt ggggggcagt acatattcaa cacctgatac tatgcgtttt
     8521 attgtgggaa gattttcctc attttctagt gaaattgaac tttttctaac atcttttgat
     8581 agatgacttc ttaatcaatt atcatttcca ttgttgtttc ttggggtttc atcccttgtc
     8641 tttgataaaa gcggagagca ccctcgttat cattccagac acttagggtt agattattgc
     8701 agccaatttc tttagcataa tagcagaaaa atgacaataa aatagcccct agatattttg
     8761 aaaggaaagc ataggggcta tatagtttaa tcaaaataaa gcaaatcttt gctggtgctt
     8821 gtaaagaggt cgaagccatc cttggtaaca acaccgcagt cttcaatacg aacaccgact
     8881 ttaccaggga tatagatacc tggttcaaca gagaagcaca tgccttcttc gatgaccatg
     8941 tcgtttcctt ccatgataga tgggaattca tggacatcca taccgatacc atgcccgaga
     9001 cggtggttga agtactcacc ataaccagct ttttcgatga cctcacgggc agcgcggtcc
     9061 acttcatgag cagtcacacc tggcttgata aagtcaagag cagcttgttg ggcttcaaga
     9121 gtcaagttgt aaatatcttt cttgaattgg tctggtttgc cgacagcgac tgtacgagtc
     9181 atatctgacg catagccatt gaccagaaca cccaggtcaa agaggagaag agcatcattt
     9241 tcaaccttat tagctgctgg aatgccgtgt ggattcgcag cattatcacc agtcaagacc
     9301 atggtatcaa agctcatttc ataaccttca cgtttcatgg caaagtcgat ttgtgcgatg
     9361 atatctgtct cagtcttatc aagagaaata ttgtcaaaac caacatgaac agccttgtca
     9421 gcataaagac ctgcaaccat cattttttgc acttcatcag ctgatttgat gaggcgcatg
     9481 cgttggatac gaggagtgag gttgtcaaac tcagcagtct caaaaactgt tttcaaacca
     9541 tggtatttgg tcaagatgag attgtcaaac tcaacagcga cacgtttgaa gtcaagttgt
     9601 ggaagagcat gtttgatttt ttgccatgga ttttcagaat cgacatagcc cactactggg
     9661 aaggaaacgg tgctacttgc acgttctact tcaagagctg ggacaaagag gagaggttcc
     9721 tgatccgcta ggacaaagag gaacatttgg cgttcatggg gatcactgta aaaaccagtg
     9781 aggtaattga ttgtgacggg gtcagatacg acagcgacgt ctagtttttc tgattcaaga
     9841 tatgttagga tttgttgtaa tttagacata tgctaccttc tttctacccc tctattttgg
     9901 caaaaaatga gagaaaatgc aagggagaag ggtaaaagaa gagacaaaaa actccgacaa
     9961 gataacggag ttctttgata tcattttcct ttgtttaaga aaagtcagcc ttgcttttga
    10021 cgtcactgta ctcttcagcg atttcttggc tgagaatgtc ctcataggca gggagttgga
    10081 tgtcctgacc atatttcttc ttgagggcag tagtaactag gcgataagcc agattggcat
    10141 tacgagagag gataggcccg tggaagtagg aaccaaagac attcttataa tgaacccctt
    10201 caccgacctt ttcttcgttg tttccatttc catagacaac ctgtcccagc ggtttttggt
    10261 catcagagag gaaggtacgg ccttggtgat tttcaaatcc atagtaggtt tcatcgaaat
    10321 cttcattgtg aatcttgatg tcaccgataa aacggttatt ggtctggttg agcgtgtagt
    10381 gtcccatgac ccctagccct tcgatacgtt ttcctgaagc ttcaacataa tattgaccca
    10441 atagttggaa accaccgcag atagccagaa ctacaccgtc gttttggatg tagttgtcaa
    10501 tgctctcttt tttagcaggt aggtcgtctg caatgatact ttgttcaaag tcttgaccac
    10561 caccgaaaaa ggcgatgtcg tagtgatttt catcaaagtc atcatggaga gaaacgatgt
    10621 caacggtcac atgggctccc agtttttcag ccacatactt gagcatgagg atgtttccat
    10681 tgtccccgta ggtattcatg agatttccgt agaggtgggc aatgttgagc tgataggggt
    10741 aattgccatc ttttgaggaa agtgaagtat aaaccattag ttcatctcct ttctaacaat
    10801 ctgacgacta gccagcagtt cacgaaattc cagcatggca gtataagttg ccagaatata
    10861 ggcatgcttg cagtcttgat tctcaatggt cttgagaact tgctccagat tactcgtttc
    10921 agtgattttc tcagctggat agccagtcac tcggaggcga cgagcgattt cagaatgacg
    10981 aacaccgcca gcgttgattt caggaatgtc catgtcagtg atttgttcaa agtctgcatc
    11041 ccagatccag ctagtgtcaa ttccatctgc atagttggca ttaaggagga cagataggct
    11101 aaatggataa ggtgctagtt tgatcatttc gatagcttgg gttgcaccga ctggattttt
    11161 aatcaagaca agggtacatt ccttgtcacc gatatgaaag gtttcttggc gtccaaagac
    11221 agcacggctc ttgtcaaatc cctgtttgat gagttgcgaa tcgacaccta ggaaacgggc
    11281 gatggccaca gcagctaggg cgttatagat attatagagc ccgccgattt ggataccgta
    11341 ttcttggccg tctatgacaa agcgagagcg attgttggtc aactcaacca gttttgtcaa
    11401 acgatagtcg agatcaggac gtttacatcc acaaccttca cagatatagg cacccaagtt
    11461 tgcataggta ttatgctcat atttgaggat gccttggcag tcaggacaga gaatcccttc
    11521 ggtattgtag tgagccagtt gggctggtcc tttttccaag tcaaaaccaa aatactctat
    11581 agggtttgga atagttggct tgtagaaaag tggactgtct ccgttaagga gaacagtagc
    11641 agttggaact ttccgaatgg catccaatat catgttatag gtagtataga tttcaccgaa
    11701 acggtccatc tggtcacgga agatattagt aatgacaaaa agactaggct ggatatagtc
    11761 acagatacga gatagactgg cttcgtcgat ttctaggacg gcaatatttt tcccagtttt
    11821 agaagatttg gctgttaaga aggttgtcgc aattcctgta atcatgttgg caccgcttgg
    11881 gttggtcaga acttgaccat aaacttcttt taaaataccg acagtgaggg cagttgtcaa
    11941 ggtttttccg ttggttccag tgaccacgac aatctcgtag ttcttagcta ggttttgtaa
    12001 aatatcttta tcaaattgaa gggcgacttt acctgggagc gtacttccac ggccaagacg
    12061 gcttaaaacg aagtgggaag aacgcccagc aagaaggccc aaagtagttt ttaagttcat
    12121 gtttctatta tatcacaaaa gagggaaaag acagatttgg tgtttcgtag aagtaaaaac
    12181 agcccaaaga gggctgtcag ttaagatgag atttcaactt aaatcgcaaa caagtcattc
    12241 aagttctcag ccaaggttgg gtgagtgaag atttgttttg tgaagtaagt gtaaggaatc
    12301 ttgttgtcca tagcaacagt aatgatgttg atgatttctt gagaaccttc tgagaagatg
    12361 cttgcaccaa gaatttcttt tgtttcagta ttaacaacag ctttgaaagc tccgcgaagg
    12421 tctccattta cgtgaccacg aggcatggct gcaacaggga tttctttcac tgcgtatgga
    12481 agtttcaaat cagctgcttg gctttcagtc aaaccaactt gtgaaagtgc aggtgtgatg
    12541 aacatagtat ttggcacatt gagacggtcc tcaagtgtgt agttgccatc tccagcaagg
    12601 tagctgtaaa caacacggaa gtcatcaagt gaaatgtaag taaattgaag accaccgttg
    12661 acatctccaa ctgcaaagac accaggaacg tttgtttgac agtgtttatc tactttaata
    12721 gcgccacgtt cagttagttc aatatctgta ttttcaagtt gaagtggttc tacatttggt
    12781 ttgcgtccag ttgcgtagag aagggcgtcg aaacggtaag tttcgtcttc agttacgaca
    12841 agcacttggt caccgtcgtt tttaatttca gtagtatgga tattttgaag caattcaata
    12901 ccgtcttctt ccatgtattg tttagcaaga gctgcgatgg aaggttctgc acgaggtagg
    12961 aatgtatcca aggcatctag gactgtaacc ttgcttccta gtttattgta aaggccagca
    13021 aattcaagac cgatatttcc gccaccaagg actccaagtt tttcaggcaa tttatccaag
    13081 ctttggatac ctgttgagtc aaagacgttt ttgcttgtag caagtccagg gattggcaag
    13141 acgtttgaaa cagcaccagt gttgatgacg atagtttcag cagtcaattc ttgtttttca
    13201 tcaccagctt ggatttcgat gactttattt gaaaggaagt gagcttcagc atcaaagata
    13261 tcgacgccag taccagcaac agtcgtatag tttttaccgt tgaggcgacc agtgatcgtg
    13321 tttttggtag aaatgacttc ttcaaaagac aagtctttct cagcagcaac tagcaaggtt
    13381 ttagttggga tacaaccaat gttgatacaa gttccaccgt acatagcctt gctgcgttca
    13441 acgagggcaa cttttttgcc agctgaagcc aatttacctg ctagtgtttt accagcttta
    13501 ccaaatccaa taacaattaa atcgtatgtt aacatttatc ttcctcctat tcgaatttca
    13561 ttctagcaca agaaaaaaac ttttgcacaa ttctgctacg gaaaagacag aaaaagataa
    13621 aaacgctttc cagacaaaaa actagtaatt ttttgacaag cttgataaac taaaatccta
    13681 tctattttta tataagatag aataaatgtt cgaaaatagg aggttttatg aaatcgaatc
    13741 gttatattat tgcctttgct ggggtcattt tacacttaat gctgggttcg acttatgctt
    13801 ggagtgttta tcgtaaccct attattgaaa aaacgggatg ggatcaggct tctgttgcct
    13861 ttgcctttag tctagcaatc ttttgtttgg gcttatcggc tgcatttatg gggcgtttgg
    13921 tagaaaaatt tggtccgaga gtcatgggga gtctatctgc ttttctatac gcaggtggaa
    13981 atatcttaac aggatttgca atagaccgtc aggaactgtg gttgttgtat ctcgcttatg
    14041 gcattttagg tgggcttggt ttgggagcgg gctatattac ccctgtgtca acgattataa
    14101 aatggtttcc tgataaacgt ggtctcgcaa caggtttagc gattatgggg tttggttttg
    14161 cttctttatt gactagtccc atagcgcaac atctcatcgc aggggtaggg cttgtagaaa
    14221 ctttttatat tttaggtgca agttacttta ttatcatgct cctagcttca caattcatta
    14281 agcgtccaaa tgagcaagag cttgcaattt tatctgcttc agggaaagaa aaaacagact
    14341 ctctgacgca agggatgact gcaaatcagg ctctaaaaag caatcggttt tatatacttt
    14401 ggattatttt ctttatcaac atagcttgtg gtttaggctt aatttcagcg gcatcgccaa
    14461 tggcacagga gatggctggc ttgtctacaa gtcatgcagc agtaatggtg ggcgttttag
    14521 ggattttcaa tggatttggt cgcttgctct gggcgagctt atctgactat atcggtcgcc
    14581 ctctaacctt tagtatatta ctgcttgtta atcttttctt ttctctctca ctttggctct
    14641 ttacagattc cgttttattt gtagtcgcta tgtctatttt gatgacttgc tatggagctg
    14701 gtttttcatt gatcccagct tatctcagtg atatttttgg aaccaaggaa ttggccgctc
    14761 tgcatggata tattttaaca gcttgggcaa tggctggttt agcgggacct attttattag
    14821 cagagactta taaaatggct cattcgtaca cacaaacctt gttcgttttt ctcattttat
    14881 acagtatcgc cttggctttg tcttattatc taggtcgttc aatcaaaaaa gaaagtcaaa
    14941 aaccgcttac atgattttct gtagaaatgg ggctatcttt tgctctggtc ttgtgttata
    15001 ctagataggt tgcaaagaaa acagtacttt tcttttgtgg aaaagaagca acacgatttt
    15061 atatctagtt atatgaaaat acgtcataaa aagaaaagta taaactaagc cctatagggt
    15121 ggcttcgcac cacctttaga aagaagaata acgtgaaatt taatgaatta aacttgtctg
    15181 ctgatttgct agcagaaatt gaaaaagctg gttttgtaga agctagtcct atccaagaac
    15241 aaactattcc tttggccctt gaaggcaagg atgttatcgg tcaagctcag actggtacag
    15301 gaaaaactgc agcctttggc ttgcctaccc ttgaaaaaat ccgtacagaa gaagcgacta
    15361 ttcaagcctt ggtcatcgct ccaactcgtg aactagctgt ccaaagtcaa gaagaactct
    15421 tccgctttgg tcgtagtaag ggagtcaaag tccgttcagt atatggcgga tcaagcattg
    15481 aaaaacaaat taaggctctt aaatctggtg cccatatcgt ggtgggaact ccaggtcgcc
    15541 tcttggactt gattaaacgc aaggccttga aattacaaaa cattgaaacc cttatccttg
    15601 acgaagcgga tgaaatgctt aacatgggct tccttgaaga catcgaagcc attatttccc
    15661 gtgtacctga gaaccgtcaa actttgcttt tctcagcaac tatgccagat gccatcaaac
    15721 gtatcggtgt tcagtttatg aaagcccctg aacatgtcaa gattgcggct aaggaattga
    15781 caacagaatt ggttgaccag tactatatcc gtgttaagga acaagaaaaa tttgacacca
    15841 tgactcgtct catggatgtg gcacaaccag aactcgctat tgtatttggt cgtaccaaac
    15901 gccgtgtgga tgaattgact cgtggtttga aaattcgtgg cttccgtgca gaaggaattc
    15961 atggcgacct agaccaaaac aaacgtcttc gtgtccttcg tgactttaaa aatggcaatc
    16021 ttgatgtttt ggttgcgaca gacgttgcag cgcgtggttt ggatatttca ggtgtgaccc
    16081 atgtctacaa ctacgatatt ccacaagatc ctgagagtta tgttcaccgt atcggtcgta
    16141 caggtcgtgc tggtaagtca ggtcaatcta ttacttttgt tgctccaaac gaaatgggtt
    16201 accttcaaat cattgaaaac ttgactaaga aacgcatgaa aggtctcaaa cctgcaagtg
    16261 tagaagaatc cttccaatca aaaaaacagg tagctctcaa gaaaatcgaa cgtgattttg
    16321 cagatgaaac cattcgtgcc aactttgaga aatttggtaa ggatgctcgc aaattggctg
    16381 ctgagtttac tccagaagaa ttggcaatgt atatcttgag tctgacagtc caagacccag
    16441 atagccttcc agaagtggag attgcacgtg aaaaaccact accgtttaaa ccatcaggta
    16501 atggtttcgg tggtaaagct aagggaggtc gtggaggccg tcgtggggac gaccgtcgag
    16561 agcgtgatcg tcgtggcaat ggtcgccgtg atgagttcaa aaaaggaagt cgtggcaacg
    16621 atcgttttga taaggaaaaa cgttaccgta aggataataa aaaaccacgc aatactttaa
    16681 gcgaaaagca aacaggcttt gttattcgta acaaaggtga taaataagaa aaagcggttc
    16741 aaaatgaatc gcttttttat ataaggagac cgaatgtgaa aaagacaaat aaaattatta
    16801 tattatcttt tataatatta tgatacacaa aaataggcga cttgtcaata gaaaaggaac
    16861 aatttaatta aaaatattct ggtttttaat taaattgtaa gtcaatgcaa gtcaataagg
    16921 aattttcaga taattattga aaaagagacg tttttatgtt ataatgatag cgattaaatt
    16981 cgaggtgaaa aatggcacat ttattagaaa aaactagaaa aattacatca attttgaaac
    17041 gctcagagga gcagttgcag gatgagctcc cttacaacgc tattacgcgt cagttagcgg
    17101 atattattca ttgcaatgcc tgcattatca atagtaaggg acgtctgctt ggctatttta
    17161 tgcgttataa aacaaataca gatcgcgtag agcaattctt ccaaactaag attttcccag
    17221 atgactacgt tcaaggggct aatatgattt acgaaacaga agcaaacttg cctgttgagc
    17281 atgatatgag tattttccct gttgagagta gagatgattt tccagatggc ttgacgacta
    17341 ttgcaccgat tcatgtatcg gggattcgcc ttggttcttt gattatttgg cgtaatgata
    17401 aaaaattcga agatgaggac ttggttcttg ttgagattgc cagtaccgtt gttgggattc
    17461 agcttcttaa cttccaacgt gaagaagatg agaaaaatat tcgtcgtcgt actgctgtca
    17521 ccatggcggt caataccctt tcttactccg aactccgtgc tgtttcagca attttagggg
    17581 aattaaatgg aaatgaaggg aagttgactg cgtcagtgat tgcagatcgt atcggaatca
    17641 ctcgctctgt gattgtcaat gctcttcgta aacttgagtc tgcggggatt attgaaagtc
    17701 gctcacttgg aatgaaggga acctatctta aggtcttgat ttcagatatt tttgaagaag
    17761 tgaagaaaag agattactaa tgacaaaggc tttaatttcg attgattata cagaagattt
    17821 tgttgctgat agtgggaagc tgacagcagg tgctccagct caggcgattt cggatgccat
    17881 cagcaaggta actcgattag cttttgaacg aggagattat atcttcttta ctattgatgc
    17941 tcatgaagaa aacgattgtt tccatccgga aagtaagtta tttcctcctc ataatctgat
    18001 tgggacgagt ggacggaatt tatatggaga tttggggatc ttttatcaag agcatggttc
    18061 agacagtcgt gtcttttgga tggataaacg ccattactca gctttttcag ggactgacct
    18121 agatattcgt ttgagagagc gtagagtgtc taccgttatc ttaacaggtg tcttgacgga
    18181 tatctgtgtc ctacatacag ctatagatgc ctataatcta ggatatgaca tcgagattgt
    18241 taaaccagct gttgcttcca tctggcctga aaatcatcaa tttgccctag gtcatttcaa
    18301 aaatacactc ggagctaagt tagtagatga aaatctaaat gaactttctg agtaacctgg
    18361 ttggtgaaaa tgaaaaaaat ttgaaaaaaa gtgttgacaa gcatcccaaa agttgatata
    18421 ctagtaaagt aatcgatgcg gggatggcgg aattggcaga cgcgcaggac taaggatcct
    18481 gtgaccgctt taggtcgtga gggttcaagt ccctctctcc gcataggaaa agagttagct
    18541 aaagctagct cttttgtatt tctctaaaaa attagggctc tttgtcaact gtagtgggtt
    18601 gaagtcagct aagctcgaga aaggacaaat tttgtccttt cttttttggc tctataatat
    18661 ttgtagtggg taaatcccct atggatatta tggagcttat ttttgtgtag aaaaaaagtc
    18721 ccatatgacc tataatgaaa agcgacaaaa caactcatta gaaaga
//
LOCUS       DAVMAH010000045        18718 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVMAH010000045 DAVMAH010000000
VERSION     DAVMAH010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18718
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.045"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(140..1075)
                     /locus_tag="VYO94_001544"
     CDS             complement(140..1075)
                     /locus_tag="VYO94_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV1760160.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1072..1932)
                     /locus_tag="VYO94_001545"
     CDS             complement(1072..1932)
                     /locus_tag="VYO94_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1760161.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2040..4202
                     /locus_tag="VYO94_001546"
     CDS             2040..4202
                     /locus_tag="VYO94_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1760162.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIYKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLEHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQFLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKNLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4294..5553
                     /locus_tag="VYO94_001547"
     CDS             4294..5553
                     /locus_tag="VYO94_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1760163.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5567..6433
                     /locus_tag="VYO94_001548"
     CDS             5567..6433
                     /locus_tag="VYO94_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1760164.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6447..7280
                     /locus_tag="VYO94_001549"
     CDS             6447..7280
                     /locus_tag="VYO94_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1760165.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7591..9033
                     /gene="gtfA"
                     /locus_tag="VYO94_001550"
     CDS             7591..9033
                     /gene="gtfA"
                     /locus_tag="VYO94_001550"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV1760166.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9171..10364
                     /locus_tag="VYO94_001551"
     CDS             9171..10364
                     /locus_tag="VYO94_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV1760167.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQL
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11050..13029
                     /locus_tag="VYO94_001552"
     CDS             11050..13029
                     /locus_tag="VYO94_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1760168.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13096..14592
                     /locus_tag="VYO94_001553"
     CDS             13096..14592
                     /locus_tag="VYO94_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1760169.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPVIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14592..15518
                     /locus_tag="VYO94_001554"
     CDS             14592..15518
                     /locus_tag="VYO94_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1760170.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15527..16594
                     /locus_tag="VYO94_001555"
     CDS             15527..16594
                     /locus_tag="VYO94_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760171.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKEWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16605..17531
                     /locus_tag="VYO94_001556"
     CDS             16605..17531
                     /locus_tag="VYO94_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760172.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            complement(17606..18718)
                     /locus_tag="VYO94_001557"
                     /pseudo
     CDS             complement(17606..18718)
                     /locus_tag="VYO94_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5527 a         3320 c         3928 g         5943 t
ORIGIN      
        1 aaaataggct ccataatatc tataagggat ttacccacta caaatattat agagacaata
       61 aaacttcaga tccgtaaaac ttaattgaat tactaatctg aagttatttt tatatcgttt
      121 atattataat tgtgttattt tacttccaac tattgagaga aatttcgcca ctatttagcc
      181 agatttcttt tccgttatca cattgaacta aaagttttcc attttctgag atgtctttag
      241 caagtccctt gtagtctttt tgctctagtg tgaaagtgac ttcttttcct agaatgaatg
      301 actgtttttt gtataggtat aatagctctt ctgctggtgt ttcgaagaaa gcacgccaga
      361 tttctatgat caattcattc cttgttatag gagctgtagc tttaaataag ctggcagctt
      421 tttcttttaa ttcctgaggg aagtctttaa tagtgaaatt gatacctact ccaataatga
      481 tatctgtgac taagccagtt tctacagagg tcattgcttc agtaaggatt cctccaattt
      541 tatgattgtt tagatagata tcattgaccc attttatgtc gacatctatt aaagttaggt
      601 tcttaatggc tttgtagaca gctccagcta caagtagtgt gtaggatggt aatttgtcat
      661 aggggagatt tggtttaaga tggagtgtca tataaattcc accttgtggt gagtagaagg
      721 aacgttgaaa acggcctcgg cctgctgttt gataggaagc tagatagagg gtatttgctt
      781 catggcctaa atcaattgct tcttttgcat ctagttgtgt tgattttgtt tcgggtttaa
      841 agctgacttt aattggaaga ttttcttcta gaatctctgg aagaataagg tcaccattca
      901 tcagtttata tcctctattt ttgatactat caatttcaat gccttcttgt tctagtcgct
      961 tgatggcttt ccaaattgat gttcggctta gggatagttt ttctgcgatt ttttctccgc
     1021 tgatatagtc ggtttcttta gataggattt ggtagacagc ttggtaggat ttcataatgt
     1081 tgcctttctt actagttggt attgagagta ttcttttctt gtatgacttg gagtctgatt
     1141 aaagtattgt ttataagctt tcgaaaaatg gagtggatct gaaaaaccta ccgagtatgc
     1201 aattaccttg atggactctt gggtattttc gagaagttgt ctagctcggt gcattcgaac
     1261 gtagagtagg tattctttgg gtgataaggt attaaattct ttgaatacgc ttgataagta
     1321 gcttctgtga acggatagtt cttttgctaa atcttgaatt gtaagtgatt gaggatagtg
     1381 gctatcaatt aatcgtttgc attcaagata gagttggtgg gttgatgaaa tattcttttt
     1441 tttctgattg ggagcaatag ttcccagatg aaacatcagt tcatgaagtt gtcccatgat
     1501 atggagttga gctaattcac ttgattttgt aatctgagcg aagcggacaa tgtctgagat
     1561 gagttttgca gtagtctggg tatgacaagt ttcagattgg atgagatagg attgatcaga
     1621 aatttgagaa agagcaaaat aatcagggga tttccctcca gtgattccta accagtagta
     1681 ggcccaaggt tctttactat ctgcttgata aaaggttagt tcctctggtt ttaatagaaa
     1741 gaaatctcct tcttttaaat caacaatttt acccttgtaa tgaaattttc cttgtccttt
     1801 agtaatgtaa tgtaggacgt atgtatcacg aatggctgga ccaaaagagt aattaggtgt
     1861 gcattcctca tatccataaa agcttagggc aaggtcgatt gttccagtct ggtattctga
     1921 aaaaactaac atgtgctacc tcctacctaa cattttacca tattcttgag acatttttct
     1981 attttagaaa gcgatttcag gtgataaaat ataatcaata aagtgatgag gtgaagtaaa
     2041 tgggagttag gatagagaat aatctatttt atgttgagag taaaaatcta agtttgatta
     2101 ttgaaaatcg aaatggctac ttacttttga aacatttagg aaagactatt aagaactata
     2161 aaggttccaa tagtgtttat gaacgagacc atgccttttc aggaaatcca acagctacta
     2221 atcgaacctt tagtttagat actcaacgtc aaatttttgg acaacatggc ttaggagatt
     2281 ttaggaaacc aaccatacag gttcagcata atgtaactga agtaacagac tttcgatttg
     2341 tagaagcaaa gattttaaaa ggtcagaatg gtccacaggg cttaccttct ccacatagca
     2401 tggacgatac agagactctt gtcttaatgt tagaagattc taaggctcaa cttagtctga
     2461 ctttgtatta tactactttt aataatgatg cgactattgc tagctacagt aaattagata
     2521 ataatagtaa tcaggaagtt gtcatctata aagatttttc ttttatggct gattttccag
     2581 ctgcagatta cgaaatagta actctgcagg gtgcttatgc tcgtgaaaag actgttagac
     2641 gtcaacaggt agaacaagga atcttttcga ttagttcaaa ccgaggtgct tctggtcatg
     2701 ctcaaacacc agctcttcta ctatgcgaac aaggagtcac agaggatgct gggaatgtgt
     2761 ttgctattca actaatgtat agtggcaact ttgaagcttt tgttcaaaaa aatcaattga
     2821 atgaagttcg ggtggctatt ggcattaatc cagaaaactt ttcttggaag ttagcccctg
     2881 aggaatactt tgaaacaccg gtagctttag tgactcattc agatcaggga ttaactggta
     2941 ttagtcatga aagtcagaat tttgtactgg agcacattat gctaagtgaa ttttctaaaa
     3001 aagaacgtcc aattctaatc aataactggg aagctactta ctttgacttt cagagagaaa
     3061 aactgttaga gttagcagat gaagctaaga aagttggcat tgaacttttt gtattagatg
     3121 atggttggtt tggcaatcgt tttgatgata atcgtgcttt aggtgattgg gttgttaatg
     3181 aggaaaaact gggtggaagt ctagaaagtc tgatttcagc tatccatgaa agaggtttgc
     3241 agtttggact ttggttagaa cccgaaatga tttctgtaga tagtgatttg tatcgtcaac
     3301 atcctgactg ggctattcag gttcctggct atgagcatac ttattctcgg aatcaattag
     3361 tacttaatct tgccaatcct caggtagtag aatacttgaa aagtgtctta gatcaattcc
     3421 tatcttatca tgatattgat tacattaaat gggatatgaa ccgcaatatc actaagctag
     3481 ggaatggatt aacttatcta gagacacaga tgcaatctca tcagtacatg ctggggcttt
     3541 acgaactcgt ttcttatctg acagagaagc acagccatat tctctttgag tcctgctctg
     3601 gtggtggtgg acgaaatgat cttggtatga tgcgctattt cccacaagtc tgggctagtg
     3661 ataatactga tgccattgca cgtttaccaa ttcaatacgg ttcatcctat ctctatccaa
     3721 ccatttctat gggggctcat gtgtcagcag taccgaatca tcagatggga cgaatgacac
     3781 cattagaaac acgtggcctt gtagcaatga tgggaaattt gggctatgaa cttgatttga
     3841 caaatttatc agatgaagag aaagctacga ttgctaatca ggtgaacttg tataaagaat
     3901 tacgaccagt agttcagtta ggacagcagt atagactaat taatcctgat actgtatcca
     3961 atgaagcagc tgtacaattt aattacggaa atcaaacgat tgtaacctac gttcgcgttt
     4021 tatctgttgt agagaccatg gaaacaactt taaaattaaa aaatttggat gaagagggac
     4081 tatataaatt acaggaaaat ggcgaagttt actcaggtgc agaactaatg tatgcgggcc
     4141 taactgttat cttatcccaa ggagattttt tgagtagaca gtatattttt agaaaactat
     4201 gatatgtact gacctcaaaa gttagattta ttctatctaa cttttgaggt gcagtttgat
     4261 aagggtgtat aaatttataa aggaggcttt ctaatggaat ggtataaaaa aatcggactt
     4321 cttgcaacta caggtttagc tttgtttggg ctcggtgctt gctccaacta tggtaaatct
     4381 gcggatgaca cagtgaccat cgagtatttc aaccagaaaa aagaaatgac caaaaccttg
     4441 gaagaaatca ctcgtgattt tgagaaggaa aaccctaaga taaaggtcaa agtcgtcaat
     4501 gtaccaaatg ctggtgaagt attgaagaca cgcgttctcg caggagatgt gcctgatgtg
     4561 gtcaatattt acccacagtc catcgaactg caagaatggg caaaagcagg tgtctttgaa
     4621 gatttgagta acaaagacta cctgaaacgc gtgaaaaatg gctacgctga aaaatatgct
     4681 gtaaacgaaa aagtttacaa cgttcctttt acagctaatg cttatggaat ttactacaac
     4741 aaagataaat tcgaagaact gggcttgaaa gttcctgaaa cctgggatga atttgaacag
     4801 ttagtcaaag atatcgttgc taaaggacaa acaccatttg gaattgcagg tgcagatgct
     4861 tggacactca atggttacaa tcaattagcc tttgcgacag caacaggtgg aggaaaagaa
     4921 gcaaatcaat accttcgtta ttctcaacca aatgccatta aattgtcgga tccgattatg
     4981 aaagatgata tcaaggtcat ggacatcctt cgcatcaatg gctctaagca aaagaactgg
     5041 gaaggtgctg gctataccga tgttatcgga gccttcgcac gtggggatgt cctcatgaca
     5101 ccaaatgggt cttgggcgat cacagcgatt aatgaacaaa aaccgaactt taagattggg
     5161 accttcatga ttccaggaaa agaaaaagga caaagcttaa ccgttggtgc gggagacttg
     5221 gcatggtcta tctcagccac caccaaacat ccaaaagaag ccaatgcctt tgtggaatat
     5281 atgacccgtc cagaagtcat gcaaaaatac tacgatgtgg acggatctcc aacagcgatc
     5341 gaaggggtca aacaagcagg agaagattca ccgcttgctg gtatgaccga atatgccttt
     5401 acggatcgtc acttggtctg gttgcaacaa tactggacca gtgaagcaga cttccatacc
     5461 ttgaccatga actatgtctt gaccggtgat aaacaaggca tggtcaatga tttgaatgcc
     5521 ttctttaacc cgatgaaagc ggatgtggat taggagtaga gagactatga aaaaagtatt
     5581 acaaaaatat tgggcatggg cttttgtggt catccccctc ttgttacaag caattttctt
     5641 ctatgtgccg atgtttcaag gagcctttta cagttttacc aactggacag gattgactta
     5701 caactacaaa tttgtcggct taaacaactt taagctcctc ttcatggatc caaaattcat
     5761 gaatgcgatt ggctttaccg caatcattac gattgccatg gtggttggtg agattgcact
     5821 cgggatcttc attgcgcgtg tcttgaactc taaaatcaaa ggccaaacct tcttccgtgc
     5881 ttggttcttc ttcccagctg ttttatctgg tttgacagtg gctttgatct tcaagcaagt
     5941 cttcaactac ggtcttccag cgattgggaa tgcccttcat attgaatttc tccaaaccag
     6001 tcttttaggg actaagtggg gagcaatctt tgcggctgtc tttgtccttc tttggcaagg
     6061 ggtggctatg cccatcatca tcttcctagc tggtttgcaa tctattccaa ctgagattac
     6121 agaggcagca aggattgatg gtgcgactag caagcaagtt ttctggaaca ttgaattgcc
     6181 ttacttgcta ccaagtgtct ctatagtctt tatcctagcc ctaaaaggtg ggctgactgc
     6241 ctttgaccaa gtctttgcca tgaccggtgg tggtccaaac aatgccacaa cctcacttgg
     6301 gctcttggtt tataactatg cctttaaaaa caaccaattc ggttatgcca atgccattgc
     6361 cgtaatcttg ttcttcttaa ttgtagtgat ttcgatcatc caattgagag tatctaagaa
     6421 atttgaaatt taagaggaga agcatgatga aacaagatga aagaaaagcc ctgattggca
     6481 aatacattct attgattcta ggatcggttc tgattttagt gccgctcctt gctaccctct
     6541 ttagttcctt caaacccact aaggatattg tagataattt ctttggcttt ccaaccaact
     6601 tcacatggga caactttagc cgtctcttag ctgatgggat tggaggctat tattggaact
     6661 ctgtcgtcat cactgtcttg tctttacttg cagtaatgat ctttatccct atggcagcct
     6721 actccatcgc tcgcaatatg agtaaaagaa aagcctttac catcatgtat accctcttaa
     6781 tcctcggaat cttcgtacct ttccaagtca tcatgattcc gattacggtt atgatgagta
     6841 aactcggttt ggctaatacc tttggtttga tcttgctcta cttgacctat gcgattccac
     6901 agaccctctt tctctatgtt ggctatatca aaatctcgat tccagaaagt ctggatgaag
     6961 cagcagagat cgatggggct aatcaattta caacctattt ccgcatcatc ttcccaatga
     7021 tgaaaccgat gcatgcgaca accatgatta tcaatgccct ttggttctgg aatgacttca
     7081 tgttgccact ccttgtcttg aaccgggatt ccaaaatgtg gactctgcct ttgttccaat
     7141 acaactacgc aggccaatat ttcaacgact acggaccaag ctttgcctct tacgtggtcg
     7201 gcattatcag tatcaccatt gtctatctct tcttccaacg ccatatcatt tcaggaatga
     7261 gcaacggggc agtgaagtaa tactcaatga aaatcaaaga gcaaactagg aagctagccg
     7321 caggctgtac ttgagtacgg taaggtgaag ctgacgtggt ttgaagagat tttcgaatag
     7381 tataagaaga gctcatggaa tctatagtct ttgacacaga ggaagagttc agcttgttga
     7441 taattctatg tagaaaacaa gaaagtagta ctttgtttat cacagtctat attagtacga
     7501 gtttgatgat aaatagagat ttaaaatgaa ttttatttat gaagccagat catatgagac
     7561 ttggcttcaa ttagaaaaag gagagtaatg atgccaattc aaaataaaac catgttgatt
     7621 acctattctg atagccttgg aaataatctt aaagacttat atgataattt ggaagagcat
     7681 tttggagatg ctattggagg agttcacctt ttaccatttt tcccatcaac aggtgatcgt
     7741 ggatttgcgc cagttgacta cgacgaagtg gactcagctt ttggtgattg ggaggatgtt
     7801 aagcgtttag gtgagagata ttatcttatg tttgatttta tgattaatca tatttctcgt
     7861 caatccaagt attataagga ctatcaagaa aaacatgaag ccagtgaatt taaagatctc
     7921 tttttaaact gggataagtt ttggccagaa aaccgtccga cacagtctga tgtagattta
     7981 atttacaagc gtaaggatcg tgcaccaaag caagagattg tgtttgaaga tggttcagtg
     8041 gaacatttgt ggaatacctt tggtgaggag cagattgatc ttgatgtgac caaagaagta
     8101 actatggaat ttatccgtaa gaccattcag cacttggcaa gtaatgggtg tgatttgatt
     8161 cgtctagatg cctttgctta tgcagtgaag aaattggata ctaatgattt ctttgtggaa
     8221 ccagatattt gggatttatt ggacaaagtt cgagatatcg ctgctgagta tgggacagag
     8281 cttttacctg agattcatga acactattcg attcagttta aaatagcaga ccatgattac
     8341 tatgtttatg attttgctct tccaatggtg acactttata ctctttacag ttccagaaca
     8401 gagcgtttgg ctaagtggtt aaagatgagc ccgatgaagc aatttacgac gctagatacc
     8461 catgatggga ttggagtagt agatgtcaag gatatcctga ccgatgagga gattgactat
     8521 gcttcaaatg aactctataa ggttggagcc aatgtcaaac gtaagtactc tagtgccgag
     8581 tataacaact tagatatcta ccaaatcaat tcaacctact attcagcgct tggagatgat
     8641 gatgtcaagt attttctcgc tcgtctaatt caagcttttg ccccaggtat tcctcaggtt
     8701 tactatgtgg gtctattagc aggcaagaat gacttgaaat tattagaaga aactaaagaa
     8761 ggtcgaaata ttaatcgtca ttactatagc aacgaggaaa tagcaaaaga agtgcaacga
     8821 cctgttgtga aggcccttct caatctattt tctttccgta accgttcaga agcctttgat
     8881 ctagaaggga ctactgagat agagacacca acagctcaca gcattgtaat caaacgtcaa
     8941 aataaagata agtccgtaac agcagtagca gaaattgatt tgcaaaatca gacttatcgg
     9001 gtaattgaga atggagttga agtaacattt tgaagccttg atatggtgga taaaataggg
     9061 tttttatttt ggaaaacgtt tcctttgttt tcaaattgct aaaaaagtgg tacaatatag
     9121 gatagcttac tattatctga atcagctgat ttggagagaa aggattcatt ttgaaatcaa
     9181 taggctttat tgaaaagctg aaggggttgt ctagtaaaga gctgatttta ttgggaatta
     9241 tcctaagtat ctttttaccc ttttatcttt ttgtagttgt actctgttta tatattatca
     9301 gtttgatttt tacaggagac atgaaaagta ttcttcagaa aatgggggag catccgatgc
     9361 tgcttctttt tcttagctat agtactgtta tatccattct tgcacaaaat tggatgggtc
     9421 ttgtggcttc agtaggaatg tttctattta ctattttctt tttgcactat cagttgattt
     9481 tatcccataa attctttcga ttgattttgc agttcgtctt gtttggtagt gtcttgtcag
     9541 ctgcttttgc cagtttagaa catttccaaa ttgtgaagaa atttaactat gcttttcttt
     9601 cacccaatat gcaggtgtgg catcagaacc gggcagaagt gaccttcttt aatcctaatt
     9661 attatggaat tatttgttgt ttctgtatta tgattgcttt ctatctgttt acaacgacca
     9721 agttgaattg gttgaaagta ttctgtgtga ttgcaggctt tgttaatctc tttggtttga
     9781 actttactca aaatcgaact gcctttcctg ctattatcgc tggagcaatt atctatctct
     9841 ttacgactat taaaaactgg aaggcctttt ggcttagtat tggggtcttc gcgattggtt
     9901 tgagtttcct cttttctagt gatttgggag ttcgaatggg tactttagac tcttctatgg
     9961 aagaacgcat ttctatctgg gatgctggga tggccttgtt taagcaaaat cctttttggg
    10021 gtgaagggcc attgacctat atgcactctt atcctcggat acatgctcct tatcatgaac
    10081 atgcccacag tctttatatt gatacgattc tgagttacgg aattgtgggt accattttat
    10141 tagttctgtc ttctgttgct cctgttcgct tgatgatgga tatgagtcag gagtcgggga
    10201 aacgtccgat tatcggcctt tatctatctt tccttacagt ggttgctgtg cacggaattt
    10261 ttgacttggc tctcttctgg attcagtcag gctttatttt cttgctagtt atgtgcagta
    10321 ttccattgga gcatcgaatg ttggtatcgg acatgacgga ttaagtttta taagtttgaa
    10381 atcttctacc ttgggtagga gattttttat acgatgggca tgtcgtggat ctgaggtgta
    10441 agtcctctgt agggatccac taccggtgaa tacaatagcg ctccccaagc ctgactatcg
    10501 tgaggtagcg gattaaaatg gtctggggat agatcgtttt aagtctgacg caggaaataa
    10561 gaattgtcag agaaagcaat agtgaaatcg taggctatga atagaaacgt gatagcgagg
    10621 agcatatagt ggacaaggta gcgagaaatt ttaaagtata aaagatagtc ttaatctata
    10681 tgtgtaaatc acgaaagtaa ttgaattcgg aataaggttg gtgtgaaaag acatagtaaa
    10741 ctgaatcttg aatactagaa tgatacttct acaatattgt tataatttaa tttgaattcc
    10801 aaaatcacat tgttccgtcc gtatttcatt ttactgtatg tcttcctaag ctccaaaatt
    10861 tctgtgtcaa atttcctatt ttcactgtag tctttgacac ttcgaacgac aatttgaatc
    10921 atatattcaa aaaaaaatga aaaatttgtg ccaacaagcc taaatattct gaaaatttgt
    10981 ttgattttta atggataatg tgatataatg gttgtcaatc tataattcac ataaacagag
    11041 gagtagaaaa tgaaaaaaaa tcgtgtattt gctacagcag gtcttgtttt attagcagca
    11101 ggtgtacttg cagcatgcag ttcttcaaaa tcatctgatt catcagcccc taaagcttat
    11161 ggctatgttt atacagcaga cccagaaacc ttggactacc tgatttcaag taaaaatagt
    11221 acaacagtag tgacttcaaa tgggattgat ggtttattca ctaacgataa ttacggtaat
    11281 cttgctcctg cagttgcaga ggattgggaa gtctctaagg atggtttgac ctacacttat
    11341 aagattcgta aaggggttaa atggtttacc tctgatggag aagaatatgc agaggtgacg
    11401 gctaaagatt tcgtgaacgg tttaaaacac gcagcagata aaaaatcaga agctatgtat
    11461 ttagctgaaa attcggttaa aggcttggca gattatctat caggaacttc aacagatttt
    11521 tcaacagttg gtgtcaaggc ggttgatgat tatacgttac aatacacttt gaaccagcct
    11581 gaaccgttct ggaactctaa gttgacctat tctattttct ggcctctgaa tgaagaattc
    11641 gaaacatcaa aaggaagcga ttttgctaaa ccaacagatc cgacatcctt gctttataat
    11701 ggtccattct tgttgaaagg gttgactgca aaatcttctg tagagtttgt aaaaaatgag
    11761 caatattggg ataaagaaaa tgtccaccta gatactatca atctagctta ctatgatgga
    11821 tcagatcagg agtcgctaga gcgtaacttc actagtggag cttatagtta tgcccgtctt
    11881 taccctacca gctccaacta ttctaaggtt gcagaagaat acaaggacaa tatctattac
    11941 acacaatcag gctctgggat tgctggtctg ggtgtgaata ttgatcgcca aagttacaac
    12001 tatacctcta aaactacaga ttcagagaaa gtagctacta agaaggcatt gcttaacaaa
    12061 gatttccgtc aagccttgaa ttttgctctt gatcgctcag cttactcagc tcaaatcaat
    12121 ggtaaagatg gagcagcttt agcagttcgt aatttatttg taaaaccaga ctttgtttca
    12181 gctggtgaga agacctttgg tgatttagtc gctgctcaac ttcctgctta tggtgatgag
    12241 tggaaaggtg tgaatttagc tgatgggcag gatggtttat tcaatgctga caaggccaag
    12301 gcagagtttg cgaaagctaa gaaagcttta gaagcagacg gcgttcagtt tcctattcat
    12361 ctggacgttc cagtagacca agcatcaaaa aactacatat ctcgtattca gtcttttaaa
    12421 caatctgtag aaacagttct tggtgttgaa aatgtcgttg ttgatattca acaaatgaca
    12481 agtgatgaat tccttaatat tacttactat gctgccaatg cttcatctga ggattgggat
    12541 gtatcaggag gagtttcatg gggtccagac tatcaagacc catctactta cctggatatt
    12601 ttaaaaacaa ctagcagtga aactacaaaa acatatttag gatttgataa tccaaatagc
    12661 ccttcagtag ttcaagttgg tttgaaagaa tacgataaat tagttgatga agctgccaga
    12721 gagacaagcg acttgaatgt ccgttatgaa aaatatgcag cggctcaagc atggttgaca
    12781 gatagttcac tctttattcc tgctatggct tcttctggtg cagcaccagt gctttcacga
    12841 attgttccat ttactggagc ttctgcgcaa acaggctcta aggggtcaga tgtttacttc
    12901 aaatatttga aattacaaga taaagtggtg actaaggaag agtatgaaaa agctcgtgaa
    12961 aaatggttga aagaaaaagc tgaatcaaat gagaaagctc aaaaagaatt ggcaagtcat
    13021 gtgaagtaaa taatttctaa tagaactttc tctccatgag gagaaggttc ttttgggatt
    13081 tttaaaggaa ataatatgaa aaaatatatt tttatgcgtg ttttgcggtc attggtttcg
    13141 attttcttag taacgacttt gacctacacg attatctata ccttggttcc tcgaaaattg
    13201 attttcaagc aggatcctaa ctataataaa attgcgacaa cggctgataa acgtgataac
    13261 tatgaaaata ctgtgtttga gcgtatgggc tacattgagt attacgatac taaagagttg
    13321 caagaaaagg caagtagcat ggattcttct gtaacagtag aagcaaatgc gaccaataaa
    13381 gctatttatg aaaagtacat caatcaatta ggtcatggtt ggactttggg agaatttact
    13441 gaaagtggtc aattctatgc tactcgtgaa attccaattt ttgaacgtgt ttttcacttc
    13501 tatgctaact tgattgacat tgaccataca aataaaatcc aagaccctga aaatccagac
    13561 ttgaaacgct accttcgttt tgaaaatgat ccagttatcg gatggtcatt ggtcggttca
    13621 ggaactaaac ataaatatct cttgtacttt aacagtcagt tcccatttgt tcatcaaaac
    13681 tttgtgaact tgaatttagg tgactcttac ccaacctatg ctaatacacc agttcttcag
    13741 gttattactc aaggtcaagg acaaaccaaa actgcccaag ttcagttccc aacaggtaag
    13801 aaaacgtctt ctgtaaatat ttactcaaga acctacaagt cacctagtca ggctgactct
    13861 cgtgaagtag ctagctatgg gaaagatgat ccttatacag cgactgaaag taattaccaa
    13921 tatccatcta tgattgtcag ctctgctatt actggtttga ttggtttggt tcttgcctat
    13981 gctcttgccg tgccacttgg ttcagccatg gctcgtttca agaacacttg gattgatagc
    14041 ctctcaacag ggactttgac cttcttgctt gctcttccaa cgattgcctt ggtttacatc
    14101 gttcgattga ttggatcatc tattgccctt ccagattcat tccctatctt gggagctgga
    14161 gattggcgtt cttacgtttt accagcagtc atccttggtt tgttgggtgc tcctgttaca
    14221 gccatttgga ttcgtcgtta catgattgac ttgcaatctc aagactttgt tcgtttcgct
    14281 cgtgcaaaag gtttgtctga aaaagaaatt tcaaacaaac acatctttaa aaatgccatg
    14341 gttccgctgg tttcaggaat tcctggtgcc attattgggg ttatcggtgg tgcaaccctt
    14401 actgaaacag tcttcgcctt cccaggtatg ggtaaaatgt tgattgactc tgtaaaagca
    14461 tctaataact ctatggtcgt tggtcttgtc ttcatcttta catgtatttc tatcttctca
    14521 cgtcttttgg gagatatttg gatgactatt attgacccac gtattaaatt gactgagaaa
    14581 ggaggcaaat aatgtctaca atcgataaag aaaaatttca gtttgtaaaa cgtgacgatt
    14641 ttgcctctga aactattgat gcgccagcat attcttactg gaaatcagtg tttaaacaat
    14701 ttatgaagaa aaaatcaact gtagtcatgt tgggaatctt ggtagccatc attttgataa
    14761 gtttcatcta cccaatgttt tctaagtttg atttcaatga tgtcagcaag gtaaacgact
    14821 ttagtgttcg ttatatcaag ccaaatgcgg agcattggtt cggtactgac agtaacggta
    14881 aatcgctctt tgacggtgtc tggttcggag ctcgtaactc catcctcatt tctgtgattg
    14941 cgacagtgat taacttggtt atcggtgttt ttgtcggtgg tatttggggt atttcaaaat
    15001 cagttgaccg tgtcatgatg gaagtttaca acgtcatctc aaacatccca cctcttttga
    15061 ttgttattgt cttgacttac tcaatcggag ctggattctg gaatctgatt tttgccatga
    15121 gcgtaacaac atggattggt attgccttca tgatccgtgt gcaaatcttg cgctatcgtg
    15181 acttggaata caacttggcg tcacgtactt tgggaacacc aaccttgaag attgttgcca
    15241 aaaatatcat gcctcaattg gtatctgtta ttgtgacaac catgactcaa atgcttccaa
    15301 gctttatctc atacgaagcc ttcttgtctt tcttcggtct tggattaccg attacagtgc
    15361 caagtttggg tcgtttgatt tcggattatt cacaaaacgt aacaaccaat gcttacttgt
    15421 tctggattcc attgacaacc cttgtcttgg tatccttgtc ccttttcgta gttggtcaaa
    15481 acttagcgga tgctagtgat ccacgtacac atagatagga gtagaaatga caaaagaaaa
    15541 aaatgtaatt ttgactgctc gcgatattgt cgtggaattt gacgttcgtg acaaagtatt
    15601 gacagccatt cgcggcgttt cccttgaact agttgaagga gaagtattag ccttggtagg
    15661 tgagtcagga tcaggtaaat ctgttttgac aaagaccttc acaggtatgc tcgaagaaaa
    15721 tggtcgtatt gcccaaggta gtattgacta ccgtggtcag gacttgacag ctttatcttc
    15781 tcacaaggag tgggaacaaa ttcgtggtgc taagattgcg actatcttcc aggacccaat
    15841 gactagtttg gaccccatta aaacaattgg tagtcagatt acagaagtta ttgtaaaaca
    15901 ccaaggaaaa acagctaaag aagcgaaaga attggccatt gactacatga ataaggttgg
    15961 cattccagac gcagatagac gttttaatga atacccattc caatattctg gaggaatgcg
    16021 tcaacgtatc gttattgcga ttgcccttgc ctgccgacct gatgtcttga tctgtgatga
    16081 gccaacaact gccttggatg taactattca agctcagatt attgatttgc taaaatcttt
    16141 acaaaacgag tatcatttca caacaatctt tattacccac gaccttggtg tggtggcaag
    16201 tattgcggat aaggtagcgg ttatgtatgc aggagaaatc gttgagtatg gaacggttga
    16261 ggaagtcttc tatgaccctc gccatccata tacatggagt ctcttgtcta gcttgcctca
    16321 gcttgctgat gataaagggg atctttactc aatcccagga acacctccgt cactttatac
    16381 tgacctgaaa ggggatgctt ttgccttgcg ttctgactac gcaatgcaga ttgacttcga
    16441 acaaaaagct cctcaattct cagtatcaga gacacattgg gctaaaactt ggcttcttca
    16501 tgaggatgct ccaaaagtag aaaaaccagc tgtgattgca aatctccatg ataagatccg
    16561 tgaaaaaatg ggatttgccc atctggctga ctaggaggaa ggaaatgtct gaaaaattag
    16621 tagaaatcaa agatttagaa atttccttcg gtgaaggaag taagaagttt gtcgcggtta
    16681 aaaatgctaa cttctttatc aacaagggag aaactttctc gcttgtaggt gagtccggta
    16741 gtgggaaaac aactattggt cgtgctatca tcggtctaaa tgatacaagt aatggagata
    16801 tcatttttga tggtcaaaag attaatggta agaaatcgcg tgaacaagct gcggaattga
    16861 ttcgtcgaat ccagatgatt ttccaagacc ctgccgcaag tttgaatgaa cgtgcgactg
    16921 ttgattatat tatttctgaa ggtctttaca atcaccgttt atttaaggat gaagaagaac
    16981 gtaaagagaa agttcaaaat attatccgtg aagtaggtct tcttgctgag cacttgactc
    17041 gttaccctca tgaattctca ggcggtcaac gtcaacgtat cggtattgcc cgtgccttgg
    17101 tcatgcaacc agactttgtt attgcagatg agccaatttc agccttggac gtttctgtac
    17161 gtgcccaagt cttgaacttg ctcaaaaaat tccaaaaaga gctcggcctg acctatctct
    17221 tcatcgccca tgacttgtcg gttgttcgct ttatttcaga tcgtatcgca gttatttaca
    17281 agggtgttat tgtagaggtt gcagaaacag aagaattgtt taacaatcca attcacccat
    17341 atactcaagc cttgctttca gcggtaccaa tcccagatcc aatcttggaa cgtaagaagg
    17401 tcttgaaggt ttacgaccca agtcaacacg actatgagac tgataagccg tctatggtag
    17461 aaatccgtcc aggtcactat gtttgggcga accaaaccga attggcacgt tatcaaaaag
    17521 gactaaacta gtaatggttt tataatttcc atgtcaattt ttatggaaat taggctcttt
    17581 gtcaactgta gtgggttgaa gtcagctaag ctcgagaaag gacaaatttc gtcctttctt
    17641 ttttgatgtt caaagcgata aaaatccgtt ttttgaagtt ttcaaagttt cgaaaaccaa
    17701 aagcattgcg cttgataagt ttgatgagat tattggtcgc ttccagtttg gcattagaat
    17761 agtgtagttg aagggcgttg ataatctttt ctttatcttt gaggaaggtt ttaaagacag
    17821 tctgaaaaat aggatgaacc tgcttaagat tgtcctcgat aagttcgaaa aatttctctg
    17881 gttccttatt ctggaagtga aaaagcaaga gctgatagag ctgatagtgg tgtttcaagt
    17941 cttccgaata actcaaaagc ttgtttaaaa tctctttatt ggttaagtgc atacgaaaag
    18001 taggacgata aaattgctta tcactcagtt tacggctatc ctgttgtatg agcttccagt
    18061 agtgcttgat agccttgtgt tcatgggatt ttcgatgaaa ctgattcatg atttggacac
    18121 gcacacgact catagcacgg ctaagatgtt gtacaatgtg aaagcgatca agaacgattt
    18181 tagcattcgg gagtgaaaca gtctaggaga ctgtttcagc ctgagcctag aaatttgaaa
    18241 gcgaagctgt ttagccaagt catagtaagg gctaaacata tccatagtaa tgattttgac
    18301 gcgacatcgg acggctctat catatttaag aaagtgatct cggatgacag cttgtgttct
    18361 accttcaaga acagtgatga tatcgagctt ttcaaaatct tgcgcaataa agctcatctc
    18421 catctcccga ttgaaacagt cactccccgg actgtttcaa cgtcccaaga cataatctta
    18481 ggcagatttc taaaattaca ctcaaagtgg aagtcattga gctttcgaat gacagttgaa
    18541 gttgagatgg aaagctgatg ggcaatatca gtcatagaaa tcttttcaat taatttttga
    18601 gcaatctttt ggttgatgat acgagggatt tggtgattct tcttgacgat agaagtttca
    18661 gcaaccataa ttttagaaca atgatagcac ttgaaacgac gctttctaag gagaattc
//
LOCUS       DAVMAH010000046        18664 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVMAH010000046 DAVMAH010000000
VERSION     DAVMAH010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18664
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.046"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            120..275
                     /locus_tag="VYO94_001558"
                     /pseudo
     CDS             120..275
                     /locus_tag="VYO94_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            475..3750
                     /gene="rexB"
                     /locus_tag="VYO94_001559"
     CDS             475..3750
                     /gene="rexB"
                     /locus_tag="VYO94_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV1760173.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDIDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEVMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILTP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLIDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            3747..7397
                     /gene="addA"
                     /locus_tag="VYO94_001560"
     CDS             3747..7397
                     /gene="addA"
                     /locus_tag="VYO94_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV1760174.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SKSFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIDSLNQESDSQAYQAVLAHVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRNRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKAHENLYEKLVNAQKKAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIDEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7567..8745
                     /locus_tag="VYO94_001561"
     CDS             7567..8745
                     /locus_tag="VYO94_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760175.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSNFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            8954..14968
                     /locus_tag="VYO94_001562"
     CDS             8954..14968
                     /locus_tag="VYO94_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1760176.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQPEPEPSNGN
                     STEDVSTESNTSNSNGNEEIKQENELDPDKKVEDPEKKLELRNVSDLELYSLSNGTYK
                     QHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQQEI
                     ESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNLAGTYHLAASLNANEVELANTD
                     NAYIKGTFTGKLIGKNNGKHYAIYNLKKSLFDSLSNATVENLSLKSVNISGKNDIGSL
                     ANEAKNGTTINEVHVDGLLGGERGIGGLVAKVDQSNITNSSFTGRIVNTYETKSAYNI
                     GGLVGHLTGDRASINSSKSTVVISSNTNSSDQTVGGIAGLVDKDAHIQNSYSEGDINN
                     SQRFGKVAGIAGNLWDRESNSENHAGRLTNVLSDVNVTNGNAISGYHYNGMKITDAFS
                     NKANKVFNVTLEKDEVVSKESFEERGTMLDASQIASKKAEINLLTPPIVEPLSTSGKK
                     DSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVKENSILYQKELLSAVMMK
                     DDQVITDIISNKQTANKLLLHYKDHSSEKLELKYKDDFANLAEYSIGDSGLLYTPNQF
                     LYDQTSIINQVLPELNRVNYQSDAVRNTLGISPEVKLTELYLEEQFTKTKQDLANSLK
                     KLLSADAGLAGDNPVTRGYLVDKIKNNKEALLLGLTYLERWYNFSYGQVNVKDLVMYH
                     PDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLASHHGTTDLFSTLENYRKV
                     FLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQELVGTKYSIGVYDRITSATWKYRNM
                     VLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLNSFVEKSAHETAERQRDH
                     YDYWYRILDEKGREKLYRNILLYDAYKFGTDHTEGKATEVADFDSPNPAMKHFFGPVG
                     NKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGP
                     EFFAKGLLQAPDQPSDATITINSILKHKTSDSTEGQRLQVLDPTTRFNDAADLQNYVH
                     NMFDVVYMLEYLEGQSIVKQLDAYQKMTALRKIENKYVKDPADGNEVYATNVVKELTE
                     EEARNLNSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAPIFSALSSEKGTPGDLMG
                     RRMAYELLAAKGFKDGMVPYISNQFEADARANNKTITSYGKTKGLVTDTLVLQKLFNG
                     QYNTWSDFKKAMYKERQDKFNKLNKISFKDPSQPWTRNIIKTIHSVNELQNLMNEAVR
                     KDTETPHWYNYNPEIDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK"
     gene            15020..15196
                     /locus_tag="VYO94_001563"
     CDS             15020..15196
                     /locus_tag="VYO94_001563"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1760177.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            15403..16254
                     /gene="ylqF"
                     /locus_tag="VYO94_001564"
     CDS             15403..16254
                     /gene="ylqF"
                     /locus_tag="VYO94_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV1760178.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LIKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            16241..17020
                     /locus_tag="VYO94_001565"
     CDS             16241..17020
                     /locus_tag="VYO94_001565"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV1760179.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            17036..18586
                     /locus_tag="VYO94_001566"
     CDS             17036..18586
                     /locus_tag="VYO94_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV1760180.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLAMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGAICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         6164 a         3591 c         3821 g         5088 t
ORIGIN      
        1 gattgaaata agatacgaac agcttgatta aggaaatcaa attaatttct agaaatattt
       61 tagcatccac gatgtactat tatagtttca atttactata gttcaatcat tctatcaaga
      121 atattgaata tataaaggca cgtaatatta aaacttcttc tgatatcgaa ttagagtccg
      181 atgttgatgg cgataaatca gacaatctac ccgtcgacat taagatactg ggacaacaca
      241 ttgaagtgta ttccgtacct aagaaacaat cataaaactc aaagtcttgc taccgaggct
      301 tttttattat gtgattttca gtagccagac ttattctatc taatacaagt aaagctaagt
      361 atttaagatt tagcagatga tgaagaaaag aaaggatggc ctaaatattt taacagattt
      421 acgaggctaa tcatggtata atatagggtg atgaaaaatt ccaacgaggc tgagatgaaa
      481 ttactttata ctgatattcg aacttctttg acagaaattc taacaagaga ggcagaagag
      541 ctagttgcag ctggcaagcg ggtcttctac attgccccca actctctttc ttttgaaaag
      601 gaacgcgccg tgctggaatg cttgtcccag caggcttctt tttcgattac cgtcacgcgc
      661 tttgctcaaa tggctcgtta tctggtcttg aatgatttac cagttaaaac tactcttgat
      721 gatatcggtc ttgggttggc cttttacaaa tgccttgccg aactcgatcc caaggacttg
      781 cgtgtttatg gcgctattaa gcaggatcct caattgatcc agcagttaat tgagctttac
      841 catgagatga ccaaatctca gatgagtttt ttggacttgg agaatttaac agatgaggat
      901 aagagggcgg atttactctt gatttttgag aaagtaacag cctatcttaa tcaaggtcag
      961 ttagcccagg gaagtcagtt gtcccatttg attgaggcta ttgagaatga caaggtaagt
     1021 agtgatttta atcaaatcac cttggtcatt gacggcttta ctcgtttttc tgctgaggaa
     1081 gagcgggttg tggacttact tcacggcaaa ggtgttgaga ttgttatcgg ggcttatgct
     1141 agtaagaaag cctataccag tccttttagc gagggcaatc tctaccaagc cagcgtaaaa
     1201 tttctccatc atctggcttc taaataccaa acgcctgctc aggactgttc tcaaactcat
     1261 gagaagatgg atagttttga caaggcctct cgtttgttgg agtcttctta tgacttttca
     1321 gaactcgctt tggatatcga tgagaaagac cgtgaaaatt tacaaatctg gtcttgtttg
     1381 acgcaaaagg aggagttgga gctagtagcc cgtagcattc gtcagaaatt acatgagaac
     1441 tcagacctga gctacaagca ttttcgtatt ctcttggggg atgtagcttc ttaccagtta
     1501 tctctcaaaa ccatttttga ccagtatcag attccttttt atcttggtag aagcgaagtc
     1561 atggctcatc atcccttgac tcagtttgtc gagtctattt tagctttaaa acgttaccgt
     1621 tttcgtcagg aggatttgat taatcttctt agaactgatt tgtatactga cctcagtcag
     1681 tctgatattg atgcttttga gcaatatatc cgctatcttg gtatcaatgg cttgccagcc
     1741 tttcagcaaa ccttcaccaa atcccaccat ggaaaattta atcttgagcg tttgaatgtc
     1801 ctccgcctga gaattttaac acctcttgaa accctctttg ccagccgaaa acaaaaggct
     1861 gaaaacctcc tacaaaaatg gagtgtcttt ctaaaagaag gagctgtgac caagcagtta
     1921 caagatttga caaccacttt ggaagctgta gaacaggaaa gacaagccga agtttggaag
     1981 gctttctgcc atgttttaga acaatttgcg actgtttttg ctggttcaca ggttagtctg
     2041 gaagacttcc tagccttgct ccattctgga atgagtttgt cccaataccg taccattcca
     2101 gcaacagtgg acactgttct ggtgcagagt tacgatttga ttgcaccatt gactgctgac
     2161 tttgtctatg ctattggact aactcaggac aatttaccaa aaatttctca aaacaccagt
     2221 cttctgacag atgaagaaag gcaaaaccta aaccaagcga ccgaagaagg cgttcaatta
     2281 ctgattgcca gcagtgaaaa tctcaagaaa aatcgctaca ctatgctttc cttggtcaat
     2341 tctgctcgta agcagttgtt cttgtcggct ccaagccttt ttaacgaaag tgaaagtaag
     2401 gaatctgcct atcttcaaga gttgatccat tttggattta ggcggagaga gaagaggatg
     2461 aatcacaaag gactgtctaa ggaggatatg gggtcctatc acagtctttt gtctagtctg
     2521 gttgcctatc accagcaggg tgagatgagc gatactgagc aagatttgac ttttgtcaag
     2581 gttctgtcgc gtgtcatagg taaaaaacta gatcagcaag gtctggaaaa tccagctatc
     2641 ccaaccagtc caagcagcaa gaccttagcc aaggacacct tgcaagctct ctatcctgcc
     2701 aaacaggagt tttacctgtc tacgtcgggt ttgacagagt tttatcgcaa tgaatacagt
     2761 tatttcctac gctacgtttt aggcttgcag gaggaattac gtttgcatcc tgatgcccgt
     2821 agtcacggga atttcttgca tcgtatcttt gaacgcgcct tgcagttgcc taatgaagat
     2881 tcctttgacc aacgtctaga acaagctatt caagaaacca gtcaagaacg cgaatttgaa
     2941 gctatttatc aagaaagttt ggaagcccag tttaccaagg aagttttgct tgatgttgca
     3001 cggacgactg gacatattct ccgacacaat ccagccatcg aaaccatcaa agaagaagca
     3061 aattttggtg gaaaagacca agcctttatt caattagaca atggacgcag tgtctttgta
     3121 cgaggcaagg tggaccggat tgaccgtttg aaagctaatg gagcgatagg agtagtagac
     3181 tacaaatcca gtctgactca gttccagttt cctcatttct ttaatgggct caattctcag
     3241 ttaccaacct atcttgctgc cctaaaaaga gaaggggagc agaacttttt cggcgccatg
     3301 tacttggaaa tggctgaacc tgtccaatct ctgatggcgg taaaaagtct ggcgggtgca
     3361 gtagtagaag ccagcaagtc aatgaaatac caagggctct tcttggaaaa agaaagcagt
     3421 tatttaggcg aattttataa caaaaacaag gctaatcaac tgatagatga ggaatttcag
     3481 ctcctactgg actacaatgc ctatctttac aagaaagctg ctgagaagat tttagcaggc
     3541 cggttcgcca tcaatcctta tactgaaaat ggcagaagca ttgccccata cgtccagcaa
     3601 catcaggcta ttacaggctt tgaagccaat taccatctgg gccaagcccg tttcctagaa
     3661 aagttggacc tagctgatgg caagcgtctg gtcggagaaa aactcaagca agcttggctt
     3721 gaaaaaataa gagaggagtt gaatcgatga agcttattcc ctttttaagt gaggaggaga
     3781 ttcaaaaact gcaagaagca gaagcaaatt cgagcaagga acagaagaaa actgccgagc
     3841 aaatcgaagc tatctacact tctggccaga atatcctggt ctcagcatcg gctggttctg
     3901 gaaagacctt tgtcatggca gagcgcattc tggaccaatt ggcgcgtggt gtcgaaattt
     3961 ctcaactctt tatctcaacc tttacggtca aggctgcaac tgaacttaaa gaacgtttag
     4021 agaaaaaaat cagcaagaaa atccaagaaa cagatgatgt cgacctcaaa caacacttgg
     4081 gacgccagtt ggcagaccta cccaacgctg ccatcggaac catggactct ttcacacaaa
     4141 aattccttgg caaacatggt tatctgcttg atattgcacc taatttccgt attttacaaa
     4201 accaaagcga gcaacttctt ctcgaaaacg aagtctttca tgaggtcttt gaagcgcatt
     4261 accaaggtaa acagaaagag acctttagtc atttgctgaa aaactttgct ggacgtggca
     4321 aggacgaacg gggtctgcgc cagcaggtct ataaaatcta tgacttcctc caatccacca
     4381 gtaatcctca aaagtggctg agtaaatctt tcctcaaagg ttttgagaaa gctgatttta
     4441 ccagtgaaaa agaaaaactg actgagcaaa tcaaacaagc cctttgggat ttggaaagct
     4501 ttttccgtta ccatctggat aacgatgcca aggagtttgc aaaggctgcc tatttagaaa
     4561 atgttcagtt aattctggat gaaattgact ccctaaatca ggagtccgat agtcaggctt
     4621 atcaggcagt gcttgcgcat gttgtcgcca tctctaagga gaaaaacggt cgagctctga
     4681 ctaatgccag ccgtaaggct gatttgaagc ccctggctga tgcctacaac gaagagagaa
     4741 agacccagtt tgctaaacta ggacaattat cagaccagat aaccattctc gactatcaag
     4801 aacgttatca tggagacact tggaaactag ctaaaacctt ccaatctttc atgagcgatt
     4861 ttgtggaggc ttatcgtcag agaaaacgac aggaaaatgc ctttgaattc gctgatatca
     4921 gccattacac cattgagatt ttagagaatt tcccacaagt tcgtgagtct tatcaggagc
     4981 gcttccatga agtcatggtc gatgagtatc aggataccaa ccatattcaa gaacggatgc
     5041 tggaattgtt gtctaatggc cacaatcgct ttatggtggg agatatcaag caatccatct
     5101 atcgtttccg tcaggcagac ccgcagattt tcaatgagaa attccaacgc tatgcgcaaa
     5161 atccccaaga aggcaagctc attctcctca aggaaaattt ccgtagtagt tcagaagtgc
     5221 tgtcagcaac caatgatgtc tttgaacgtc tcatggacca agaggtcggc gaaatcaact
     5281 atgataacat gcaccagctt gtttttgcca ataccaaact gactcccaat ccagacaaca
     5341 aggccgaatt tctcctctac gacaaggacg atacaggtga ggaagaagag agtcaaacag
     5401 aaacgaaact aacaggtgaa atgcgcttag ttatcaagga gatccttaaa cttcatcagg
     5461 aaaaaggtgt tgcctttaag gaaattgccc ttctgacctc tagtcgtaat cgtaatgacc
     5521 aaattctact tgccctgtct gagtacggga ttcctgtcaa aactgacgga gagcaaaaca
     5581 attatctcca atccctagaa gtgcaagtca tgctagacac tcttcgtgtc attcacaatc
     5641 ccctgcaaga ctacgccttg gttgccctta tgaagtctcc aatgtttggt tttgatgagg
     5701 atgagctagc acgtttgtcc cttcagaaag cagaggataa agcccacgaa aatctctatg
     5761 agaaactggt caatgcacaa aaaaaggcaa gtagtcaaaa aggcttgatt cacacagctc
     5821 tagctgaaaa actaaagcaa ttcatggata tcctagcttc ttggcgcttg tatgccaaac
     5881 cccactctct ctatgacttg atttggaaga tttacaacga ccgtttttat tatgactatg
     5941 ttggggcttt gccgaatggt cctgctaggc aggccaatct ctatgcccta gcactgcgtg
     6001 ctgatcaatt tgaaaagagc aatttcaaag gtttgtcgcg ttttattcgt atgattgacc
     6061 aagtcttaga agcccagcac gatttggcaa gcgtggccgt cgcaccgcca aaagatgcag
     6121 tagagctcat gaccatccac aagagtaaag ggctggagtt tccttacgtc tttatcctca
     6181 atatggatca agatttcaac aagcaagact ctatgtcaga agtcattctc agtcgtcaga
     6241 atggtcttgg tgtcaaatat attgccaaga tggagacagg ggcagtagaa gaccactatc
     6301 ctaaaaccat caaactctcc attcctagtc tgacctatag gcagaacgaa gaggaattac
     6361 agctagcaag ctattctgag cagatgcgtt tgctgtatgt tgctatgacg cgggctgaga
     6421 aaaagctcta tcttgtcggc aagggttctc gtgaaaagct ggaagccaag caatacccag
     6481 cagccaaaaa tgggaaacta aatagcaata ctagactgca agcacggaat ttccaagatt
     6541 ggctttgggc tatcagtaaa gtgtttacta aggacaagct caactttagt tatcgtttta
     6601 ttgacgaaga tcagttgacc agagaagcta tcggagagtt ggaaaccaag agtcctctcc
     6661 aagatagctc ccaagcagac aatcgtcagt cagataccat caaagaagct ctagaaatgc
     6721 tgaaggaggt ggaagtttat aatactcttc accgcgcagc tattgaactt cctagtgttc
     6781 aaaccccaag tcaaatcaag aaattctacg aaccagttat ggatatggaa ggtgtcgaga
     6841 ttgctggtca aggtcagtca gtaggcaaga aaatcagctt cgatttgcca gatttttcaa
     6901 ccaaagaaaa ggtaactgga gctgagattg gtagtgctac tcacgaactc atgcagagaa
     6961 ttgacctcag ccagcaacta acccttgcta gcctaacaga aacactcaaa caagttcaaa
     7021 ctagccaagc tgtcagagac aagatcaatc ttgataaaat tcttgctttc tttgacacag
     7081 tactcggtca ggaaattctt gctaataccg accatctcta tcgcgagcaa cctttctcca
     7141 tgctcaaacg agatcaaaag agtcaggaag actttgttgt ccgtggtatc cttgatggct
     7201 atctgcttta cgaaaacaaa attgttctgt tcgactacaa gacagaccgc tatgatgaac
     7261 caagtcaact cgtagaccgc tatcgtggtc agttagctct atacgaagag gctttatcac
     7321 gagcctattc gattgaaaat attgaaaaat acttgatttt actcggtaaa gacgaggttc
     7381 aagttgtaaa agtataactt atactctttg aaaatctctt caaaccacgt cagcttcgcc
     7441 ttgctgtata tatggttact gacttcgcca gttctatcta caacctcaaa acagtgtttt
     7501 gagctgattg cggctagctt tctagtttgc tctttgattt ttattgagta ttagaaagga
     7561 gacctcatga cacttccagt tagaaaatcc ctgcacgatg cagttttaca ggcttcgaaa
     7621 gcggatactt gggaacaagc taccaaggaa tggaatgaag tttccttgat ttttaacggt
     7681 atcggccgta gcaattgtgt ctgtggaaat gccatcaaat acgcttatga actctttaac
     7741 ggtgtcacag gccaacgcct ctttccaatt ggtagcgact gtgttcgtca ttttcatcga
     7801 ttgtcccttg accagcaatt ggaagaggaa gaaaaactgc tcagaaaggt tgaaaatcta
     7861 accagaaaag ctcagaaaaa ggaaaaaatc aaggtcaata aaagtaactt tgacgagcga
     7921 cttctaaaat ggctctggga aaaaggtgtt ttcaaaccca atcgtggcaa tcaatttgcg
     7981 cctgagagag actaccagct tttcctagaa gtctttcagg gaggaagttg gaccaaggcg
     8041 gaaccaaaga aaaaggctcg gatggaagaa gtccttgaaa agtgtatcaa acccttttta
     8101 cttgggaaat cggatgacca actctacctt gtcaagctag gcaaggagaa aattgactac
     8161 gaacaagaac tccgtatcca ggcagagaaa gaacgcaaga agagggataa aatcgccaag
     8221 caatatgcag acaatctggt tctagccatg ggacccgcag agcgtgctta tcaagattac
     8281 tttggcttta cagagaccct gactcaagaa gaacgcaagt gggaaaaaat tctttttggt
     8341 aaaaatagag cagaacgggc tatcaaggcc aaacaatacc aaaaagagct ggaaaaagac
     8401 caacgaattg ccagtcagga tccaattgaa agaaaacaga agcagacttg gctcctcaat
     8461 tcctattttc gtgagcttcc tgaagaaaaa gctcgatttt ctaggctctt attagaatat
     8521 cgaaaaaatg gtgaagtacc cttttcaact gaatacctgt cagatcatct catcgacttt
     8581 ttctataaaa tgaaagcctt tgaatttgaa atcgcaccag aacaagtccg agattttcta
     8641 aaaaaaagcc tgcaggaaga ccatcgctca tcagcacaag gaagctggat agaaggaatt
     8701 ctcctcaact gcctcaaacc atttttagaa cgattagtga tatgagtaac acctaccgtg
     8761 taaatttcat ggtaggtgtt attgtacccc caaataatat aaaacaaagt atgaaagcgc
     8821 atctcaattt taagactttt ttgtaaatta agagtataat taaggtatac tgccttttct
     8881 atagataata gataatacac taatataata aaggtctttg taacatatat aaattttatt
     8941 tcaaggagga ataatggaaa agtattttgg tgaaaaacaa gagcgttttt catttagaaa
     9001 attatcagta ggacttgtat ctgcaacgat ttcaagttta ttttttatgt ctgtattagc
     9061 tagttcatct gtggatgctc aagaaactgc gggagttcac tataaatatg tggcagattc
     9121 agagctatca tcagaagaaa agaagcagct tgtctatgat attccgacat acgtggagaa
     9181 tgatgatgaa acttattatc ttgtttataa gttaaattct caaaatcaac tggcggaatt
     9241 accaaatact ggaagcaaga atgagaggca agccctagtt gctggtgcta gcttagctgc
     9301 tctgggaatt ttaatttttg ctgtttccaa gaaaaaggtt aagaataaaa cggtattaca
     9361 tttagtattg gttgcgggaa taggaaatgg tgtcttagtt tcagtccatg ctttagaaaa
     9421 tcatcttttg ctaaattaca atacggacta tgaattgacc tctggagaaa aattacctct
     9481 tcctaaagag atttcaggtt acacttatat tggatatatc aaagagggaa aaacgacttc
     9541 tgattttgaa gtaagtaatc aagaaaaatc agcagccact cctacaaaac aacaaaaggt
     9601 ggattataat gttacaccaa attttgtaga ccatccatca acagtacaag ctattcagga
     9661 acaaacacct gtttcttcaa ctaagccgac agaagttcaa gtagttgaaa aacctttctc
     9721 tactgaatta atcaatccaa gaaaagaaga gaaacaatct tcagattctc aagaacaatt
     9781 agccgaacat aagaatctag aaacgaagaa agaggagaag atttctccaa aagaaaagac
     9841 tggggtaaat acattaaatc cacaggatga agttttatca ggtcaattga acaaacctga
     9901 actcttatat cgtgaggaaa ctatagagac aaaaatagat tttcaagaag aaattcaaga
     9961 aaatcctgat ttagctgaag gaactgtaag agtaaaacaa gaaggtaaat taggtaagaa
    10021 agttgaaatc gtcagaatat tctctgtaaa caaggaagaa gtttcgcgag aaattgtttc
    10081 aacttcaacg actgcgccta gtccaagaat agtcgaaaaa ggtactaaaa aaactcaagt
    10141 tataaaggaa caacctgaga ctggtgtaga acataaggac gtacagtctg gagctattgt
    10201 tgaacccgca attcagcctg agttgcccga agctgtagta agtgataaag gcgaaccaga
    10261 agttcaaccg acattacccg aagcagttgt gaccgacaaa ggtgagactg aggttcaacc
    10321 agagtcgcca gatactgtgg taagtgataa aggtgaacca gagcaggtag ccccattgcc
    10381 agaatataag ggtaatattg agcaagtaaa acctgaaact ccggttgaga agaccaaaga
    10441 acaaggtcca gaaaaaactg aagaagttcc agtaaaacca acagaagaaa caccagtaaa
    10501 tccaaatgaa ggtactacag aaggaacctc aattcaagaa gcagaaaatc cagttcaacc
    10561 tgcagaagaa tcaacaacga attcagagaa agtatcacca gatacatcta gcgaaaatac
    10621 tggggaagtg tccagtaatc ctagtgattc gacaacctca gttggagaat caaataaacc
    10681 agaacataat gactctaaaa atgaaaattc agaaaaaact gtagaagaag ttccagtaaa
    10741 tccaaatgaa ggcacagtag aaggtacctc aaatcaagaa acagaaaaac cagttcaacc
    10801 tgcagaagaa acacaaacaa actctgggaa aatagctaac gaaaatactg gagaagtatc
    10861 caataaacct agtgattcaa aaccaccagt tgaagaatca aatcaaccag aaaaaaacgg
    10921 aactgcaaca aaaccagaaa attcaggtaa tacaacatca gagaatggac aaccagaacc
    10981 agaaccatca aacggaaatt caactgagga tgtttcaacc gaatcaaaca catccaattc
    11041 aaatggaaac gaagaaatta aacaagaaaa tgaactagac cctgataaaa aggtagaaga
    11101 tccagagaaa aaactcgaat taagaaatgt ttccgaccta gagttataca gtttgtcaaa
    11161 tggtacttat aaacaacaca tttcgttaga gcaagttcca agcaatccaa atagctactt
    11221 tgttaaagtg aaatcttctt cattcaaaga tgtataccta ccagtagcat caatatcaga
    11281 ggaaagaaaa aatgataaaa tcctttataa aatcacagca aaagtagaga agcttcagca
    11341 ggagatagaa agcagatata aagataattt taccttctat ctagctaaga agggaacaga
    11401 agaaacaaca aactttactt cctttagtaa tctggtcaaa gctataaacc aaaatctggc
    11461 aggaacttat catttagcag caagtttaaa tgctaacgaa gtagaattgg ctaatactga
    11521 taacgcttat attaaaggaa cttttactgg taagctaatt ggtaaaaata atggtaaaca
    11581 ttatgctatt tataatttga aaaaatctct tttcgatagt ttaagtaatg caacagtaga
    11641 aaacttaagt ttgaaatcag ttaatatttc tgggaaaaat gatattggtt cattggcaaa
    11701 tgaagctaaa aatggaacaa ccattaatga agttcatgtt gacggtctct taggaggtga
    11761 acgtggtatt ggtggtttag tggctaaagt ggatcaatcc aatatcacaa atagtagttt
    11821 tactggaaga attgttaata cttatgaaac gaaatcagca tataatattg gtggtttagt
    11881 aggacattta actggagata gagcatctat taacagctca aaatcaacag tggtcatttc
    11941 atcaaataca aatagttctg accagaccgt tggaggtatc gctggtcttg tagacaaaga
    12001 tgcgcatatt cagaatagct attctgaagg ggatattaat aatagccaac gctttggaaa
    12061 agttgctggt atagcaggta acttatggga tcgtgaatca aatagtgaaa atcatgctgg
    12121 aagattgact aatgtgctta gtgatgtcaa tgtaactaat ggaaatgcca ttagtggtta
    12181 ccattataat ggaatgaaaa ttactgatgc atttagtaat aaagcgaata aagttttcaa
    12241 tgtcacttta gagaaggatg aggtcgtcag caaagaatcc ttcgaggaaa gaggaacaat
    12301 gctagatgct tctcaaattg caagcaaaaa agcagaaatc aatcttctca ctccaccaat
    12361 agtggaaccc ctctcaacaa gcggtaagaa agacagtgat ttttctaaga tagcccatta
    12421 tcaagccaac cgtgctttgg tttataagaa cattgaaaaa ttgttacctt tctataacaa
    12481 ggcgaccatc gtgaaatacg gaaacctggt taaggagaac agtatcttat atcaaaaaga
    12541 actcttgtct gcagttatga tgaaggatga ccaagtaatc acagatatta tttccaacaa
    12601 acagactgca aacaaactct tgcttcacta caaggaccat tcatcagaaa aactagaact
    12661 taagtataag gatgattttg ccaatttggc agaatatagc attggtgata gtgggcttct
    12721 ctatacgcca aatcaattct tgtatgacca aacctctatc atcaatcaag ttttacctga
    12781 attgaatcga gtaaattatc aatcagatgc tgttagaaat acacttggaa tttcaccaga
    12841 agtgaagcta acggagttat atcttgaaga acaatttacc aaaacaaagc aagatttggc
    12901 aaacagtttg aaaaaactct tgtctgcaga tgctggactt gctggtgaca acccagttac
    12961 cagaggctat cttgtagata aaatcaagaa caataaggaa gccttactac tcggtttaac
    13021 ttatttagaa cgttggtata actttagcta tggtcaagtg aatgtcaaag acctagttat
    13081 gtatcatccg gacttctttg gtaaaggaaa tacttcacca ttagatactc tgattgagtt
    13141 aggtaaatct ggctttaaca atcttcttgc taaaaacaat gtcgatactt atgctatcag
    13201 ccttgccagc catcatggaa cgacagattt gtttagcacg ttggaaaatt accgaaaagt
    13261 ctttctacca gataaaacca ataatgactg gtttaaatca cagactaagg cttacattgt
    13321 cgaagaaaaa tccaatatcg aagaggtgaa aacgaagcaa gaactagttg gcactaagta
    13381 ttctattggt gtctatgacc gtatcactag cgccacatgg aaataccgta atatggtact
    13441 acctctactt accttgccag aaagatccgt atttgtcatt tcaaccatat ctagtctagg
    13501 ttttggtgct tatgatcgct atcgtaataa agaacatcaa gcaaatggtg atcttaatag
    13561 ctttgttgaa aagagtgctc acgaaacagc agagcgtcaa cgagatcact atgattattg
    13621 gtatcgtatt ctagatgaaa aagggcgtga aaagctttat cgaaatatct tgctttatga
    13681 tgcctataaa tttggaactg atcatactga aggaaaggct acagaagtag cagattttga
    13741 tagtccaaat cctgcaatga aacatttctt tggacctgtt ggaaataagg ttggacataa
    13801 tggacatggt gcttatgcta caggggatgc cgtttattat atgggttatc gtatgttgga
    13861 caaggacggc gccattactt atacgcatga gatgacacat gactcagatc aggacattta
    13921 tcttggaggt tatggaagaa gaagtggact tggacctgag ttctttgcta aaggcttact
    13981 acaagcacca gaccaaccaa gtgatgcaac cattaccatc aactctatct tgaaacataa
    14041 aacatcagat agtacagaag gtcagcgatt gcaagtactt gatccaacta caagatttaa
    14101 tgacgcagca gatcttcaga actacgtcca caatatgttt gatgtcgttt acatgttgga
    14161 atatctcgaa gggcaatcta tcgtgaaaca gttagatgct tatcagaaaa tgacggccct
    14221 gagaaaaatc gagaataaat acgtgaaaga tcctgcagat ggaaatgagg tttacgctac
    14281 taacgtagtc aaagaattga cagaagaaga ggcccgaaac ctgaatagtt ttgatagttt
    14341 gattgacaat aatattcttt cagctcgtga gtataaggct ggtacatatg agagaaatgg
    14401 ctactttact ataaaactct ttgcaccaat cttttcagca ttgagcagtg agaaaggtac
    14461 tcctggagat cttatgggac gtcgtatggc ctatgaacta ttagctgcaa aaggctttaa
    14521 agatggtatg gtgccatata tctcaaatca atttgaagca gatgctaggg caaataataa
    14581 aacgattacc tcatatggta agaccaaagg attagtaaca gatacattag ttcttcaaaa
    14641 attatttaat ggacaataca atacctggag tgattttaag aaagctatgt ataaagaacg
    14701 tcaggataaa ttcaataaat tgaacaaaat ttcatttaaa gatccgtctc aaccttggac
    14761 gcgcaatatt attaagacaa ttcacagtgt aaatgaactg cagaacttaa tgaatgaagc
    14821 tgtccgcaag gatacagaaa ctcctcattg gtataactat aatccagaaa tagacagtgc
    14881 agttcataag ttgaagagag caatctttaa agcctatctt gaccaaacaa atgattttag
    14941 aagttcaatt tttgagaata aaaaatagtg tttactatta ggaaataaag tttaaaaagg
    15001 tgatgaagaa caaaccaaga ttcaagcagg aattcctact gataatgaag taagttatgc
    15061 tcttatttat cagcaggaaa ctcttcctgc aacaggttca tcaacttctg cgcttacagc
    15121 tttaggccta ttagctgttg gtagtttagt tcttttggtt cataatatga cgggaacagt
    15181 tttttgctcc ctctgaaaag tcatcatttg atggcttttt tctatatagg gtaaaaggct
    15241 atcatcggac aaaataaaga aggcatgata taatataaag tagatttcta tgtcataaaa
    15301 caagaactgt ttggacatca tccatttgaa gactctctat gttcaaacta tagtaaaata
    15361 aaatagggga tctaaatcct tgctacgaaa ggaaaaaact caatggctac tattcaatgg
    15421 tttcctggtc acatgtctaa agctcgtcga caggtgcagg agaatttaaa atttgttgat
    15481 tttgtgacga ttttagttga tgcacgctta cctctatcta gtcaaaatcc tatgttgatc
    15541 aagattgttg gtgataaacc aaaactcttg attttaaaca aggccgactt ggctgatcca
    15601 gcaatgacca aggaatggcg tcagtatttt gaatcacaag gaatccagac gctagctatc
    15661 aactccaaag agcaagtgac tgtaaaagtt gtaacagatg cggccaagaa gctcatggct
    15721 gataagattg ctcgccagaa agaacgtggg attcagattg aaaccttgcg taccatgatt
    15781 attgggattc caaacgctgg taaatcaact ctgatgaacc gtttggctgg taaaaagatt
    15841 gctgttgttg gaaacaagcc aggggtcaca aaaggtcaac aatggcttaa aaccaataaa
    15901 gatctggaaa tcttggatac accggggatt ctctggccta agtttgagga tgaaactgtt
    15961 gcacttaagt tggcattgac tggagctatc aaggatcagt tgcttcctat ggatgaggtt
    16021 accatttttg gtatcaatta tttcaaagaa cattatccag aaaagctggc tgaacgcttc
    16081 aaacaaatga aaattgaaga agaagcgcct gtgattatta tggatatgac ccgcgccctc
    16141 ggtttccgtg atgactatga ccgtttttac agtctcttcg tgaaggaagt ccgtgatggc
    16201 aaactcggta actatacctt agatacattg gaagacctcg atggcaacga ttaaagaaat
    16261 caaagaactc cttgtgacag tcaaggagtt agaaagccct atttttttag agcttgaaaa
    16321 ggataatcgc tcaggagttc aaaaggaaat cagcaagcgt aaaagagcca tccaagctga
    16381 attagatgaa aatttgcgct tggaatccat gctttcttat gaaaaagaac tttataagca
    16441 aggattgacc ttaattgcag gtattgatga ggttggtcgt ggtcctcttg ctggtcctgt
    16501 agtcgctgcg gccgttattt tacctaaaaa ttgtaagatt aaaggtctca acgacagcaa
    16561 gaaaattcct aaaaagaaac atctggagat tttccaagcc gttcaagacc aagccttgtc
    16621 gattggaatt ggtatcatag ataatcaggt catcgaccaa gtcaatatct atgaagcaac
    16681 caaactagcc atgcaagaag caatctccca gctcagccct caaccagagc accttttgat
    16741 tgatgccatg aaactggact tgcccatttc acaaacctcc attatcaaag gagatgccaa
    16801 ctccctctct atcgcagcag catctatagt agccaaggta acacgtgatg aattgatgaa
    16861 ggaatacgat cagcagttcc ctggctatga tttcgctact aatgcaggat atggcacagc
    16921 taaacatctg gaaggcctca caaaactagg agttacccca attcaccgaa ccagctttga
    16981 gcccgttaaa tcactggttt taggtaaaaa agaaagttaa ttgaaaggaa ataccatgga
    17041 ggaacagtct gaaatagtcc gttctaagaa agaattcgcc tttgcatcca gcactatact
    17101 atcccaagtt ggtcgaggaa tcattgtcgg cctcatcgtt ggaattatcg tcggatcctt
    17161 tcgtttctta attgaaaagg gcttccacct gatacaagga gtttatcaag atcaagggta
    17221 cttagtgcgc aatctttttg tactggtttt gttttatata ctcatctgtt ggctcagtgc
    17281 caaactaaca cggtcagaaa aagatattaa aggctcagga attcctcaag tcgaagccga
    17341 actgaaaggc ctcatgtccc tcaactggtg gggcattctt tggaaaaaat atgtgctagg
    17401 tattcttgct attgccagtg gactcatgct gggtcgagag ggacccagta ttcaacttgg
    17461 agcagttggt ggtaaaggaa ttgccaagtg gctcaaatcc agtccagtag aggaacgctc
    17521 tttgattgcc agtggagctg cagcaggttt agccgcagcc tttaatgctc ctattgcagc
    17581 acttctcttt gttgtagaag aagtctatca ccatttttcg cgctttttct gggtctcaac
    17641 tctagcagcc agcatcgtag caaactttgt gtctctactc atgttcggtt tgacaccagt
    17701 attggatatg ccagataaca ttcctcccat gaccctagat cagtattgga tatatctcgc
    17761 catgggaatt ttccttggat tttcaggctt tctctatgag aaagctgtat taaacgttgg
    17821 aagagtttat gacttgattg gtcaaaaaat ccatttggat agagcttatt atcccatctt
    17881 ggcttttatc cttatcatac cagtcggaat cttcttacct caaatcattg gtggcggaaa
    17941 tcagcttgtc ctttctttaa ctgaacaaaa ttttagtttc caagttttat tagcttactt
    18001 tttgatccgc tttatttgga gtatgattag ctatggaagt ggactgccag gaggaatttt
    18061 cctccccatt ttagctcttg gttctttgct tggtgcctta attggtgcta tctgtgtcaa
    18121 tcttggactt gtcagtcaag agcaattccc tatatttgtc attctaggaa tgagtggcta
    18181 ttttggagcc atatcaaaag ctcccttaac cgctatgatc ctcgtaactg agatggtagg
    18241 agatattcgc aaccttatgc cacttggtct tgtcactctt gtttcttata ttatcatgga
    18301 tttgctcaaa ggtacgccag tctatgaagc catgctggaa aaaatgcttc cagaagaagt
    18361 atctagcgaa ggagaagtta cacttatcga aataccagtt tctgataaaa ttgctgggaa
    18421 acaagttcat gaactcaact taccacacaa cgtcctcatc acaactcaag tccataatgg
    18481 caagagccaa acagttaacg gctcaaccag aatgtatctg ggtgatatga ttcacctggt
    18541 tattccaaaa agtgaaattg gaaaagtcaa agatttgttg ttgtagtatg atcatttaca
    18601 taacataaat tatgtaaatg atcagtttga tttatttaga aaaccgattc tcagaaatga
    18661 gatc
//
LOCUS       DAVMAH010000047        18320 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVMAH010000047 DAVMAH010000000
VERSION     DAVMAH010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18320
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.047"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            331..1377
                     /gene="pheS"
                     /locus_tag="VYO94_001567"
     CDS             331..1377
                     /gene="pheS"
                     /locus_tag="VYO94_001567"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV1760181.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1377..1886
                     /locus_tag="VYO94_001568"
     CDS             1377..1886
                     /locus_tag="VYO94_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760182.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GIGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1963..4368
                     /locus_tag="VYO94_001569"
     CDS             1963..4368
                     /locus_tag="VYO94_001569"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV1760183.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDN
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTVAVPVDFFYA
                     KGILEALFTRLGLAVAYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4436..5437)
                     /locus_tag="VYO94_001570"
     CDS             complement(4436..5437)
                     /locus_tag="VYO94_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1760184.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5593..6038
                     /locus_tag="VYO94_001571"
                     /pseudo
     CDS             5593..6038
                     /locus_tag="VYO94_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6122..6388
                     /locus_tag="VYO94_001572"
     CDS             6122..6388
                     /locus_tag="VYO94_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV1760185.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARHEQGINQRKLEEL
                     SGVSQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            6649..8898
                     /gene="metE"
                     /locus_tag="VYO94_001573"
     CDS             6649..8898
                     /gene="metE"
                     /locus_tag="VYO94_001573"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV1760186.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLNLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSFVAAYQEVFAKLADLGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLFQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            8962..9828
                     /gene="metF"
                     /locus_tag="VYO94_001574"
     CDS             8962..9828
                     /gene="metF"
                     /locus_tag="VYO94_001574"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV1760187.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIILDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10513..12726
                     /gene="pnp"
                     /locus_tag="VYO94_001575"
     CDS             10513..12726
                     /gene="pnp"
                     /locus_tag="VYO94_001575"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV1760188.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12742..13359
                     /gene="cysE"
                     /locus_tag="VYO94_001576"
     CDS             12742..13359
                     /gene="cysE"
                     /locus_tag="VYO94_001576"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV1760189.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13371..14255
                     /locus_tag="VYO94_001577"
     CDS             13371..14255
                     /locus_tag="VYO94_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760190.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYQLAKLSNLEVLLADSSY
                     QEQISQLKFQAFSGEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14342..15685
                     /locus_tag="VYO94_001578"
     CDS             14342..15685
                     /locus_tag="VYO94_001578"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV1760191.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDADIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15678..16064
                     /locus_tag="VYO94_001579"
     CDS             15678..16064
                     /locus_tag="VYO94_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV1760192.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16068..16952
                     /locus_tag="VYO94_001580"
     CDS             16068..16952
                     /locus_tag="VYO94_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV1760193.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDMIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            17194..17628
                     /locus_tag="VYO94_001581"
                     /pseudo
     CDS             17194..17628
                     /locus_tag="VYO94_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17936..18106
                     /locus_tag="VYO94_001582"
                     /pseudo
     CDS             17936..18106
                     /locus_tag="VYO94_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         5518 a         3519 c         4150 g         5133 t
ORIGIN      
        1 tcatcttatt tcaatccgct ataaagttag ataagaataa gctaacaagc agaagtaaga
       61 taggtcttgc aagaatggta aaaatctgat aaactaagta gtaattgaat agggatctga
      121 aagactagta gcccaaggga agtatatcag ggaggagagc cgtgactgca agctctctat
      181 atgaaagctg ggtgaattca cttgcgcatg gatttagaaa tgaaggtctg acttgtcaga
      241 tgaaaacgga tggtaccgcg tgtcaacgct ccgagtggag tttttggcat gtggttttct
      301 ttttatctac gagagactga tggaggaaat atgtcaacta ttgaagaaca attaaaagcg
      361 cttcgcgaag aaacgctggc tagcttgaag cagattactg ctggaaatga aaaagagatg
      421 caagatttgc gtgtctctgt ccttggtaaa aagggttcgc tcactgaaat cctcaaaggg
      481 atgaaagatg tttctgctga gatgcgtcca atcatcggga aacacgtcaa tgaagctcgt
      541 gatgtcttga ctgctgcttt tgaagaaaca gctaagctct tggaagaaaa gaaagtcgcg
      601 gctcaactgg ctagcgagag tatcgatgtg acgcttccag gtcgtccagt tgcgactggt
      661 caccgtcacg ttttgacaca aaccagtgaa gaaatcgaag atatcttcat cggtatgggt
      721 tatcaagtcg tggatggttt tgaagtagag caagactact ataactttga acgtatgaac
      781 cttcccaaag accacccagc tcgtgatatg caggatactt tctatatcac tgaagaaatc
      841 ttgctccgta cccacacgtc tccagttcag gcgcgtgcta tggatgccca tgatttttct
      901 aaaggtcctt tgaagatgat ctcgccaggg cgtgtcttcc gtcgcgatac ggacgatgcg
      961 acccacagtc accaattcca ccaaatcgaa ggcttggtag ttgggaaaaa tatctctatg
     1021 gctgatcttc aaggaacgct tcagttgatt gtccaaaaaa tgtttggtga agagcgtcaa
     1081 attcgtttgc gtccatctta cttcccattc acagagccat ctgttgaggt ggatgtttct
     1141 tgcttcaagt gtggtggaga aggctgtaac gtatgtaaga aaacaggttg gatcgaaatt
     1201 atgggagccg gtatggttca cccacgtgtc cttgaaatga gtggtatcga tgcgactgta
     1261 tactctggtt ttgcctttgg tcttggacaa gagcgtgtag ctatgctccg ttatggaatc
     1321 aacgatatcc gtggattcta ccaaggagat gtccgcttct cagaacagtt taaataatga
     1381 ttagaaaagt agaaatggca gatgttgagg tgttggctaa aattgccaaa caagcctttc
     1441 gtgaaacctt tgcgtatgat aatacggaag agcagttaca ggaatacttt gaagaggctt
     1501 atagtctgaa aactttgtca actgagttgg gaaatcctga ctctgaaacc tatttcatta
     1561 tgcatgagga ggagatagct ggttttctca aagtcaactg gggaagtgct caaactgaga
     1621 gagaattaga ggacgctttt gaaattcaac gcctctatgt gctacaaaaa ttccaaggat
     1681 ttggaatagg taagcaactg tttgaattcg cacttgaact tgctacaaaa aatagttttt
     1741 cttgggcttg gctaggtgtt tgggagcata atacaaaagc tcaagcgttt tataatcgat
     1801 atggttttga aaaatttagc caacatcatt ttatggttgg tcaaaaagta gatacggatt
     1861 ggttactgag aaagaaatta aggtaagaag aggattcttc tattgaaatg ataggaaagg
     1921 aaaagaacca gtgtggcaat ggtcattctg gagaactaaa ttatgcttgt atcttataaa
     1981 tggttaaaag aattggtgga cattgatgtg ccatcacagg agttggctga aaaaatgtca
     2041 accacaggga tcgaggtaga gggtgtcgaa tcaccagctg ctgatctctc aaaaattgtt
     2101 gtcggtgagg tcttgtcttg cgaagatgtg ccagagactc acctccatgt ttgtcaggtt
     2161 aacgttggcg aagaagaagc ccgtcagatc gtttgtggtg ccccaaatgt gcgtgctggg
     2221 atcaaggtca tggtggctct tccaggagct cgtatcgctg ataactacaa aatcaaaaaa
     2281 ggaaaaatcc gtggtttgga gtcacttgga atgatctgtt cacttggtga attggggatt
     2341 tctgactcag ttgtgcctaa ggaattcgca gatggcatcc aaatcttgcc tgaagatgcc
     2401 gtgccaggtg aggaagtctt ttcttaccta gacttggatg atgaaatcat cgaactttcc
     2461 atcacaccaa accgtgcaga tgccctttct atgtgtggag tggctcacga agtggcagcc
     2521 atctatgaca aggcagtcaa ctttaaagaa tttactctaa cagaaactaa tgaagctgcg
     2581 gcagatgccc tttctgtcag cattgagaca gacaaggcgc cttactatgc agctcgtatc
     2641 ttggacaatg tgaccatcgc accaagtcca caatggttgc aaaaccttct catgaacgaa
     2701 ggaatccgtc ccatcaataa cgtagtggac gtgaccaact acatcctgct ctattttggt
     2761 caaccaatgc atgcctttga cttggataac tttgaaggga ctgacatccg tgtgcgtgaa
     2821 gcgcgtgctg gtgaaaaatt ggtgaccttg gacggtgaag aacgtgactt ggacgtgaat
     2881 gacctagtca tcactgtcgc agacaagcca gtagcccttg caggtgtcat gggtggtcaa
     2941 gcaacagaaa tctctgaaaa atctagtcgt gttgtccttg aagctgctgt tttcaatggc
     3001 aaatctatcc gtaagacaag tggtcgcctg aaccttcgtt ctgagtcatc ttctcgcttt
     3061 gaaaaaggaa ttaatgtggc aacagttaat gaagcccttg atgcggcagc tagcctgatt
     3121 gcggaacttg caggtgcgac ggtgcgtaag ggcatcgttt cagcgggtga gcttgatact
     3181 tcagatgtag aagtttcttc aacccttgct gatgttaacc gtgtcctcgg aactgagctg
     3241 tcttatgctg atgtcgaaga cgtcttccgt cgtcttggct ttggtctttc tggaaatgca
     3301 gacagcttta cagtcagagt cccacgtcgt cgttgggata tcacaatcga agctgacctt
     3361 tttgaagaaa ttgctcgtat ctatggttat gaccgcttgc caactagtct accaaaagac
     3421 gatggtacag caggtgaatt gacagccaca caaaaactcc gccgtcaagt tcgtactatt
     3481 gctgaaggag caggtttgac agaaatcatc acctatgctc taacaactcc tgaaaaagca
     3541 gttgagttta cggctcaacc aagtaacctt actgaactca tgtggccaat gactgtggat
     3601 cgttcagtcc tccgtcaaaa tatgatttca ggtatccttg ataccgttgc ctacaacgtg
     3661 gctcgtaaga ataaaaactt ggccctttac gagattggaa aagtctttga acaaacaggt
     3721 aatccaaaag aagaacttcc aaatgaaatc aacagttttg cctttgcctt gacaggcttg
     3781 gttgctgaaa aagatttcca aacagtagca gttccagttg atttcttcta tgctaaagga
     3841 atcctagaag cgctctttac tcgcttggga cttgcagtgg cttatacagc aacagctgaa
     3901 attgctagcc ttcatccagg tcgaacagcc gtgatttcac tcggtgacca agttcttggt
     3961 ttccttggcc aagtgcatcc agtcactgct aaggcttatg atattccaga aacgtatgta
     4021 gctgagctta acctttcagc tatcgaagct gcgcttcagc cagcgactcc atttgtagaa
     4081 atcaccaaat tcccggcagt cagccgtgac gttgcccttc tcctcaaggc agaagtgact
     4141 catcaagaag ttgtagatgc tatccaagct gccggcgtga aacgtttgac agatatcaaa
     4201 ctctttgacg tcttctcagg tgagaaattg ggacttggta tgaagtcaat ggcttatagc
     4261 ttgaccttcc aaaatccaga agatagctta acggacgaag aagtcgcacg ctatatggaa
     4321 aaaatccaag catcgctcga agaaaaagtg aatgcagaag tgcgttaaac gatagtatga
     4381 tacaaattcc ccctctagtt tatgaacact agaggggtga ttttatataa aataattaaa
     4441 atgtgatttc tgtaaaaata catctatgat cagagttttg aaaacttaca atgtctaaat
     4501 ctttaacata gtagtggttt ttaggcaata aaatatgatc tattgttgca ttaaaaagtt
     4561 ttggactttg gctattccaa gttcctcttt caaaaggtgg cagtacattt aatgcgtccc
     4621 tatgagagct tatttttgca agtgctccat gacgcatagt tgcattaaaa tcacctgcaa
     4681 taatagcctt tggatatttt gaagccaatt gattatgaat gatgtttaag tcttgcttcc
     4741 agatttccat taaacctggc agaggaggag cagtatgcaa ggcaatgata tctggtatat
     4801 tttgttttct cgaatgtaat acaattgtcc caaaccgtgt tgtatgaaaa gttttagctt
     4861 ctgtatagaa accataactt ttcttgacaa tcacagtcac aggagctatt ccactattgg
     4921 taggtggaga agtgaaaata tcatagttgg ccatagaaag tccaacttga tgaaacaata
     4981 gtttgattct ctggttttct tgctcacctc tgatattggt agctagttca gggaatatag
     5041 ccatatcggc atcaaaatgg ctaaaaattc gctcaatatg ttgtgcttct atttgattag
     5101 cgacgttcca agttactaat tttaaggttt tagtcttatt tgatgcagaa gaaagggttt
     5161 tatctgttcc gaataatagt aatatgagcg atagtaagag caaaatgcca gagtaaaacc
     5221 gtatttgttt atttttcttg taaaaagata gggaaaaaaa tacgaaactt aaaatagaag
     5281 ccatagttgc agtagctaag gggaaggcat aaatctgtgc caagataggt ctggtagata
     5341 gccaaatatt aagattagaa gatggaaaaa aagaataagc tatgataggg ataacaaaga
     5401 gaatgaccga aagggcagag agaaatgttt taatcattgt gtgagtacct caatttgcaa
     5461 tggttgctcg gagctaatgt gactttgtga ctttacttga ttgatattct ttttattgtc
     5521 ttccttatag attaagtaca acccaagtaa aaaaagtcca atttaagatt gaaatgatta
     5581 aaaggcacag aaatgcaaga caattatact acaaaaggca aacatttgac aatcgatagc
     5641 cgtcgcttaa tcgaacgatg gaaaaaagaa ggaaaatcaa atagagaaat tgcctctcta
     5701 cttggaaaag ctcctcaaac tatccatact gaaatcaagt atgggacagt ccgacaatgt
     5761 cttggaaaag ggcgcttcaa agagatttat tctgccgact acgctcaaca gtcttaagaa
     5821 actaaaggaa aagattctcc actatacata accaaaaatt ttcgcctgaa atgatggtta
     5881 tggctaaagg ggttaacgtg ggaatttcaa ccatttacta ttggattcat catggaaaat
     5941 tggggttaag caaacaggat ttgctttatc ctagaaaagg aaaagcgctt aagaaacaag
     6001 ctagtcccaa ttttaaacct gctggtcagt ctatcgaatc ataattcgct cattttttca
     6061 aaaatacata gacgtaaaag aaagagggtt aagtgatgaa gaatagtgct attgggagta
     6121 attggaagga tgtccatctg agctctttag caaggaggaa atccttgaaa gtgatatgcg
     6181 agtggctatt atgagcgagt tgattgaagc tagacatgaa caaggaatca atcagagaaa
     6241 gctagaagaa ctcagtggag tgagtcaacc tgtcatagct aggatggaaa caggagagag
     6301 cagtcttcag ttggatacgg tcttaaaagt tctaaccagt ctaggaaaga cactagcagt
     6361 cgttccactt gaacagggga aaagttgact agaatcagtt atagtctttt ctaataacag
     6421 gtcatagtca cttataagaa ttactaataa catgttttag tattctaatt ggaatatagc
     6481 tgtaaagtaa gaattacaaa ggatttgaga cgtttgcttc aagtcttttt cttttgtccg
     6541 aaacagatat atagtttcaa actatatcaa accctaattt tttacaatta tacagacgct
     6601 ttcttttctg ttaagatagt ttcaacaaca aattttggag gacacatcat gtcaactaca
     6661 atcatcggtt tccctcgttt gggcgaattc cgtgaattaa aatttacaac tgaaaaatac
     6721 tttagaaaag aaatctcaga agaagaactt ttagcagccg caaaagactt gcgtgctaaa
     6781 cactggaaca ttgtcaaaga aaaaggcatc actgaaattc catcaaatga cttttctcac
     6841 tatgataact tcctagatgc agctttcctt ttcaacgtag tacctgcatc cgttcaaaac
     6901 ttgaacttgt ctgaccttga gcgctacttc gctttgggac gtggttacca aggagaaaaa
     6961 ggggacgttc gcgccctccc aatgaagaaa tggtttaata ctaactacca ctacatcgtt
     7021 cctaaatttg aaaaagacac tcaagtcaaa cttgcaggtc acaagatttt cgatgagttc
     7081 caagaagcca aagaacttgg attgaacact cgtcctgttc ttgtaggtcc cttcactttc
     7141 cttcaattgt cagactttga agaaggcgtg aaagcagacg acttcgtaga tagctttgtg
     7201 gctgcttacc aagaagtttt tgctaaattg gctgaccttg gtgcgactcg catccaattg
     7261 gatgaagcgg ctcttgtaaa agacttgaca gctgaagaaa aagctctctt cttgaacctt
     7321 tacaacaaac tcttggctga caaaaaaggt cttgaagtct tgtttcaaac ttatttcggt
     7381 gatgttcgtg acgtatacgc tgaccttgta aacttgccag tagatgctat cggtcttgac
     7441 tttgttgaag gtaagaaaac tcttgaactc gttaaaggtg gcttcccagc tgacaagact
     7501 ctctatgcag gtattgtcaa tggtaaaaac atctggcgca acaactacga aaagagcttg
     7561 gctgttcttg agcaaatccc agctgaaaac atcgttttga caagctcttg ctcacttctt
     7621 catgtgccat ttacaactgc taatgaagaa tttgaaccag cactcttgaa ccactttgcc
     7681 tttgcagttg aaaaattgga tgaaatccgt gacttggatg ctatccgcaa tggtcaaggt
     7741 tcagaagctc ttgcagccaa caaagaactc tttgcgactg agcgtgttgg tgaaaatgct
     7801 gaacttcgtg cgcgtatcgc tggcttgaca gacgcagact acactcgttt gccagccttt
     7861 gcagaacgtg aagctatcca agaagaagct ttcaaacttc cagctcttcc aacaacaacg
     7921 attggttcat tccctcaaac aaaagaagtt cgtgccaaac gtttggctta ccgtaaaggt
     7981 gaattgtctc aaaaagagta cgacgctttc cttgctgaaa cgattgacga atggatcaag
     8041 tggcaagaag atattgactt tgatgtcctt gttcacggtg aatttgagcg taatgacatg
     8101 gttgagtact tcggtcaaaa cttgtcagga tacctcttct ctaaaaatgg atgggtacaa
     8161 tcatacggta tgcgtggggt aaaaccacca atcatctggg gtgatgtcac tcgtcttaac
     8221 cctatcactg ttaaatggtc tagctatgca caaagtcgta caaacaaacc tgttaaaggt
     8281 atgttgactg gacctgttac catccttaac tggtcattcc cacgtgaaga catctctatc
     8341 aaggattcaa ctctccaaat cgcccttgct atcaaggatg aagtacttga ccttgaagct
     8401 gctggtgtga aaatcatcca aatcgacgag gctgctcttc gtgaaaaatt gccactccgc
     8461 cgtagcgact ggtacgaaga ctaccttgac tgggctattc ctgccttccg cttggtacac
     8521 tcaacagtcg cgccagacac acaaatccac actcacatgt gttactcaga atttacagat
     8581 atcatcccag ctatcgataa catggatgca gacgttattt cctttgaagc tagccgttca
     8641 aaccttgaaa tcttggacga actcaaagcg aaaaacttcc aaacagaagt gggacctggg
     8701 gtttacgata tccactcacc tcgtgtacca aatgaaggcg aaatcgacaa cacaatcgaa
     8761 gccatccttg ctaaagtgcc aagcaagaaa gtttggatca accctgactg tggtttgaaa
     8821 acacgtggta tcccagaaac aaaagaaagc ttgatccgcc ttgttgaagc agctaaagct
     8881 gcgcgtgaga aattgtaaga ttggatttct ctccatacag tggttgttca aaaagaaatc
     8941 aactagaaaa ggttattaca tatgtcacgc caaacaccgt cactctcatt tgaagtgttc
     9001 cctccaaacc cagccgtggg taatggtaac attatttcag ccttgcagga tatgcaggag
     9061 ttggctcccc attttatcag tgtaactgcc agcaataata aatttaatat caaggaaacg
     9121 acggttcgtt tggctgactt tatccaaaat gatttggcga ttccgaccat tgcccacttg
     9181 ccagctattt atctaactaa ggacaaggtt gctgaaacta ttgctgactt ggacaaagtt
     9241 ggggtgcaga aaatcttggc tcttcgtggg gatattattc tagacgtgga accacaaaag
     9301 gatttccgct atgcaaccga cttgattgag tttatcaagg aacaaacccc tcactttgat
     9361 attattggag cttgctatcc agaagggcat ccagattcgc caaatcagat ttcagatatt
     9421 caaaatctta agaagaaagt ggatgcaggc tgttcgagcc tcgtaactca gctcttcttt
     9481 gacaatgagc gcttctatga ttttcaggac aagtgtatct tggctgggat tgatgttccc
     9541 attcatgcag gaattatgcc aattctgaat cgaaatcagg ctctccgact cttgaagact
     9601 tgtgagaata tccatcttcc acgcaaattt aaagccatct tagacaagta tgagcatgac
     9661 cctgagtcgc tcagagcagc aggacttgcc tatgcagtgg accaaatcgt ggacttggta
     9721 actcaggatg ttgccggtgt gcatctctat acgatgaata atgctgatac agcaaaatac
     9781 atccatcaag caacccatgc cttgtttaat caccagtctc taggataata aaagcaaacc
     9841 attcttctca ggtgagggga atggttcctt tttaatggta aagacctcac tttttaagaa
     9901 aaatatgata aaatagattc tgtacgtact tgatacaaag atgaaggtat taaataatac
     9961 aatgcattta aactgtaaga tttaacgaca cgagtgagtc aaatcgatgt tatttgacga
    10021 aagagttagt aaagcattta gctaatcgcc cgatagcgat tagcgtgaaa gctttagata
    10081 ctttaatatt aaacctttct aatgatgtat cttgaaaact gaacacgcct acaactctgt
    10141 ggaaaaagat aaatctgcct aggagcagtc gctccgtcgt tcgatttcct attttccttt
    10201 gagttgcttg acggcttggt atcttgatga cttgaatttt ggtctcattt cttaggaaaa
    10261 aagataagct tcctagcact cgtcgagtgc gacgtcacct tcctattttt ctacagaaat
    10321 gttcggcaag ccgaaccgtc caaaatatct tgtgtaattg aacacggccg aaaagctgtg
    10381 taaaaaagat aaactgtctt gtcttcatcg aagacttcgt cagtttccta tttttacttt
    10441 gcttttgacg tccttggtat cttgatcttt gtaggcaagg cgtataattt catcaatcca
    10501 aaggggatta aaatggcaaa acaagtgttt caaacgactt ttgcgggtcg tgagttaatt
    10561 gtagaaactg gtcaggttgc taagcaagca aatggctctg ttgtcgtacg ttacggtgag
    10621 tcaactgtct tgactgctgc cgttatgtct aagaaaatgg caactgggga tttcttccca
    10681 ctccaagtca actacgaaga aaaaatgtat gcggctggga agtttcctgg tggctttatg
    10741 aaacgtgaag gacgtccttc aacagatgcg accttgacag cgcgtttgat tgaccgtccg
    10801 attcgtccta tgtttgcgga aggtttccgt aatgaagtcc aagtcatcaa tacagtgctt
    10861 tcttatgatg aaaatgcatc tgcaccaatg gctgctatgt ttggttcatc tttggcactg
    10921 tctatttcag atattccatt tgacggacca attgctgggg tacaagtggg atatgtagat
    10981 ggccaaatca tcatcaaccc aagtcaagaa caagcagagc aatctcttct tgaattgaca
    11041 gtagctggaa ccaagcacgc tatcaacatg gtagagtctg gtgccaaaga attgtcagaa
    11101 gaaatcatgt tggaagcgct ccttaaaggg cacgaagctg tcaaagaatt gattgccttc
    11161 caagaagaaa tcgttgctgc tgtcggtaaa gaaaaagcag aagtggaatt gcttcacgtg
    11221 gatgctgaat tgcaagctga aatcattgca gcctacaaca gtgacctcca aaaggcagtt
    11281 caagtagaag agaaattggc ccgtgaagct gcgactcaag tagtgaaaga ccaagtgact
    11341 gccgtttacg aagaaaaata tgcggaccac gaagaatttg accgtattat gcgtgatgtg
    11401 gctgaaatct tggaacaaat ggaacacgca gaagtgcgac gtttaattac agaagacaag
    11461 gtgcgtcctg atggtcgtaa ggtcgatgaa atccgtcctt tggatgcggt tgtcgacttc
    11521 cttcctcgtg tacatggttc aggtctcttt actcgtgggc aaactcaagc tctttcagtc
    11581 ttgaccttgg ctccgatggg agaaactcaa atcattgatg gtttggatcc agagtacaag
    11641 aaacgcttta tgcaccacta taacttccct caatattctg taggggaaac aggtcgttac
    11701 ggtgcgccag gtcgtcgtga aatcggtcac ggtgcccttg gtgagcgtgc tcttgctcaa
    11761 gtcttgccaa gcttggaaga attcccatac gctatccgtc tagtagcaga agttttggaa
    11821 tcaaacggtt cttcatctca agcttctatc tgtgcgggaa ctcttgccct tatggctggt
    11881 ggtgtgccaa tcaaggcgcc agtagctggt attgctatgg gacttatctc agatggaaat
    11941 aactacacag tattgacaga tatccaaggt ttggaagatc actttggaga tatggacttc
    12001 aaggttgcag gtactcgtga tgggattaca gcccttcaaa tggatatcaa gattcaaggg
    12061 attactgcag aaatcttgac ggaggctctt gctcaagcca agaaagcgcg ttttgaaatc
    12121 cttgatgtca ttgaagcaac cattccagaa gttcgtctag aattggctcc aactgctccg
    12181 aaaattgata cgatcaagat tgatgtagac aagattaaga ttgtcatcgg taagggtgga
    12241 gaaaccatcg acaagattat cgctgaaaca ggtgttaaga ttgatataga cgaagaagga
    12301 aatgtgtcta tctactctag tgaccaagat gctattaacc gtgccaaaga aattattgct
    12361 ggtttggttc gtgaagccaa agtggatgaa gtttaccgtg ctaaagtcgt tcgtatcgag
    12421 aaatttggtg cctttgttaa cctctttgat aagacagatg cccttgttca tatctctgag
    12481 atggcttgga ctcgtaccaa tcgtgtagag gatttggtag aaatcgggga tgaagttgat
    12541 gttaaggtta tcaagattga tgaaaaaggc cgtatcgatg cctctatgaa ggctcttcta
    12601 cctcgtccgc caaaacctga gcatgatgaa aaaggtgaaa agtctgagcg ccctcaccgc
    12661 ccacgtcatc acaaggatca caaacctaag aaagaattta cagaaacacc aaaagattca
    12721 gagtaagaaa aggagaaatg tatggggtgg tggcgcgaaa ccattgatat cgtaaaagaa
    12781 aatgatccag cggcccgcac cactttggag gttttgctga cttatccagg tgtcaaggcc
    12841 ttggcggccc accgtctctc gcattttctc tggaagtacg acttcaaact cttagctcgt
    12901 atgcacagtc agttttggcg cttttggact cagattgaga ttcatccagg agcccagatt
    12961 gattcaggtg tctttattga ccatggttct ggtctggtga ttggagagac agcgattgtt
    13021 gaaaaaggcg ttcttctcta tcacggagtg actctcgggg gaacagggaa agactgtggc
    13081 aaacgccatc cgactgtacg aaagggagcc ctcatatcag cccatgccca agttatcggg
    13141 cctgtggaaa ttggtgaaaa tgccaaggtc ggtgctgcag cagttgtcgt agcagatgta
    13201 cctagtgatg tgacggttgt cggtattccg gccaagattg tccgtcttca tggtaagaaa
    13261 gatgagcctg ttattcacga agtcgaagaa aaacgggagt attatgtcaa taaactcgag
    13321 caggctaaag atgccagtca cagatcgtct ggtttgtaga ggatacctat atgattcaag
    13381 caagaaacaa gttaagccaa gaagagctat ctgaggcgaa aaaagtaatt aactgttgcc
    13441 aaaactatga cggtacctat cgcgatccct atctctctaa catgcttaat tttgatccaa
    13501 acatgcccgc ctttttcctt tattatgaaa aaggcgaact tgttggttta ttaactgtct
    13561 atgcagatga ccaagatgta gaagtgacga tactggttca tccaggtcat cgccgtcagg
    13621 ggattgcgcg tgcattgttt actagttttg agagagaaac agcttctttc cccattcggt
    13681 cagtcacttt tcagacagaa cgtatttttt tagagaatca tcctgacttt gccagtaact
    13741 ggggactaat cgaggatgaa gagacagaaa cctggttagg taaggataga agaccatatc
    13801 agttagcaaa actttctaat cttgaagttt tgttagcaga tagttcgtat caggagcaaa
    13861 ttagccagtt aaaatttcag gcattttcag gggaacatga atcgagagaa gttgtggata
    13921 gatatgtcgc tgaagctctg aaggatccag aaagtcgctt atatattttg ttaaaagacg
    13981 gtcaggttat tgggacttgc acggttgatt tatcgagcga tacgaattac ttctacggtt
    14041 tagcaatatc agaacctgaa cgtgggaaag gctatggaag ctacttagca aaatcccttg
    14101 tcaaccaact aattgagcaa aatgataagg aatttcagat tgcagtggaa gatagcaatg
    14161 taggtgccaa acgtttgtat gaaaaaattg gctttgtcaa acagacacag gtggtttatc
    14221 tgaatgagaa aggagcaagg gattccgaag tgtagagaca ttcggactga aatttacttg
    14281 agctcttagt ttagtgatga aactaacagt tcttggattt tagctttcct gattatgatt
    14341 tatgattaaa atctatgaca ccatgtctcg tgatttgcga gaatttgtcc cgattgagga
    14401 cggcaagatc aagatgtatg tttgtgggcc aaccgtgtac aactatattc acgtgggaaa
    14461 cgcccgttcg acggtagctt ttgatacgat tcgtcgctat tttgagtacc gtgggtataa
    14521 ggttgcctat atttccaatt ttacagatgt ggatgataag attatcaacc gtgccaggga
    14581 agaaggcatc acacctcagg aggttgcgga taagtacatc gctgcctttc gtgaggatgt
    14641 gacggcctta ggcgtgaaac ctgcgactcg ccatccgcgt gtagtggagt ttatggcaga
    14701 catcatccgt tttgtggaag acttgatcga gaaaggcttt gcctatgaga gtcaagggga
    14761 tgtctatttc cgtgtagaaa aatcccacaa ctatgctaaa ttggctaata aaaccttgga
    14821 agatttggag ctaggtgctt caggtcgtac cgatgaagaa acggctcgta aggaaaatcc
    14881 tgtagatttt gctctatgga aatcttccaa accaggtgag atttcttggg atagtccttg
    14941 gggacctgga cgtccgggtt ggcatattga gtgttcagtc atgtcgacag agattttagg
    15001 tgataccatt gatatccacg gtggtggagc tgacctagag tttccacacc acaccaatga
    15061 aattgcccaa tctgaagcta aaacaggcaa ggcttttgct aactactgga tgcacaatgg
    15121 ctttgtcaat atcgacaatg tcaaaatgtc taagtccttg ggtaacttca ttacggtaca
    15181 cgatgccctt aaaactcttg atgggcaagt acttcgtttc ttctttgcga cccagcacta
    15241 ccgtaagcct atcaacttca cggaaaaggc agttcgcgat gccgagacca atctcaagta
    15301 tctgaagaat acttacgaac aaccatttac aggaaacgtg gatgcccaag agttacaaaa
    15361 ctttaaagat aagtttgtag cagctatgga tgaagatttt aatgctgcca acggtatcac
    15421 agttgtcttt gaaatggcca aatggatcaa ctcagggaac tatgatgcaa gtgtcaagca
    15481 agctcttgca gatatgttag aaatttttgg aattgtcttt gttgaggaag ttttggatgc
    15541 agatattgaa gacttgattc aaaaacgcca agaggcgcgt gccaatcgtg actttgcgac
    15601 agcagaccaa atccgtgacc aattggttac tcaaggaatt aagctccttg ataccaagga
    15661 tggagtgagg tggacacgtg attgatgtca atctcattaa cgggattgcg ctagcctttg
    15721 agggggatgc ggtgtattct atgtatattc gccgtcacct catcctcaaa ggtatgacca
    15781 aacccaataa actccatcaa gaagcaacca agtatgtgtc agccaaggct caggctcgcc
    15841 tgattgctct catgttggag gagcaggtcc taacggaaaa agaagaagaa atctacaaac
    15901 gtggccgcaa taccaatagc cacacaaagg ctaaaaatgc agatgtcgtg acttatcgta
    15961 tgtccacggg atttgaagcg gttatgggct atctccatat gactgagaat ctggaacgtc
    16021 ttgagagttt ggtttcatgg tgcatccaaa aagtggaggg ctagaacatg agggaaaaag
    16081 aactacaaga ctggtttcct gaggctcgga tttcagacca accagtagag aaagagggct
    16141 atctcacgct ccctttagct tctcagcagt ggattttgct ggaggaagct gggctcagcg
    16201 agcgtgaaaa gcagttggtt gcccttttga cccagcagga gcaggctcgt tcgctaaacc
    16261 cttggtattc ctatctggtt gaaggcaagg gacaggcacc gcaagttttt aaaaagattc
    16321 agttggttta ttgccatctt tcttattttc agcaggaaaa tctggcttct tggctagata
    16381 tgatgcggac tctttttccg aattgtcaga cagtgctaca ggtcggagct caggattatg
    16441 ttttcgtgct tcaacaagac aaatacactt ctgtaagaga tattttaagt gatatgattg
    16501 aagcagttga gtatgacttt ggacttcgtc tttctatcat gttgggtcag gtttggtctc
    16561 agacaggaca tcaagcccta tcagacttaa tcaaagctga gcgggatttg ttcaagacat
    16621 ggtggcgtca gggtcaccaa ggtgttcata ctttttctca gctctatctt tggagtatgg
    16681 gagaaagact cgtggacttg aagccaatta aagaatgtct acaccagatg attttggatc
    16741 aagatcagat tcaggaaatc attctctctc tttgggaaaa tagtgctgtt ctcactaaaa
    16801 cagcccagca actctatctg caccgcaatt ctctccaata caagattgat aaatgggaag
    16861 agttgacagg gcttcagttg aaagagttga ccgacctgac cttgtgttat caattgattt
    16921 taggttcttt gtcaactata gttggtttgt aaagaagtta atatttggag aagaggattg
    16981 ccatcttctc catttttatg tgcagagtta tagtggcttg atgctgggaa agtacactgt
    17041 gactgctaat actcaatgaa aatcaaagta caaactagga agctagccgc aggctgtact
    17101 tgagtacgtc aaggtgaagc tgacgtggtt tgaagagatt ttcgaagagt ataaaacatt
    17161 cctagaagtt gctttgattt ccctaatcta tttatgtgaa ttttatgtta ttttactata
    17221 acagttgttg ctaatccaaa taatagtggg gaagttcatt tagatgtaag cattgaagat
    17281 aatcagggag gtagtgggta taatttcagt tctgtttcaa gtagctcaca aacagctaaa
    17341 tatgaaggag ctggttataa taacaattca tcattatata taacgattga taaaacgtct
    17401 gatgcaacag ctcttttgaa attaaagttg aataatgtta ataatcaacc tgctactgaa
    17461 gttcctagtt caggaattac tgtaaaatta aatgctaaag ataatgctgg aaactggaca
    17521 agtgcttcga ataaaaaaga agtaacagta aaaattgttt ctgctaaacc gacatatcca
    17581 gacaaaattt tagtgaaaaa tcctgataat ataaaagata cagaaaaaaa tgccattatt
    17641 gaaaaattga aagaggcaaa taaaaatcat ccaacaggag ctccaacctt tgctaaaggt
    17701 gaaggagagc atgcaaatga tattgtagca acttattcag atggtacaac ttattatgta
    17761 ccgttaaatg atgtgacaaa atatgcgagg tagtggctgt accactcact tattcacctc
    17821 cccgtgattt gtagtagtga taggctttct cactattatt ataaaacaaa ataaagatca
    17881 caacactttt tcattctgtg ttgtgccttg agtgaaacga aaggaatgaa ttataaatat
    17941 gaaaagtata gtcactagca tagatgagcg cttgcgtact cgcctacgag tgattatctg
    18001 gaagcaatgg aagaagaaat cgagacgatt atggggattg cttaagttag gggttcctaa
    18061 atggatagca gataaggtat ctggctgggg cgaccactat caattatagt aaaatgaaat
    18121 aagagtagga cgaatcgatc agggcagcca aatcgatttc taacaatgtt ttagaagaag
    18181 aggtgtacta ttctagtttc aatctactat agtagctcag aagtcggtac ttaaacgtgc
    18241 tatatcaaaa ccagtccttg aaaaacgtga acaggtttcg tgtttggatt attaccttga
    18301 acgacatgcg ttaaaagtta
//
LOCUS       DAVMAH010000048        16961 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVMAH010000048 DAVMAH010000000
VERSION     DAVMAH010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.048"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            271..366
                     /locus_tag="VYO94_001583"
                     /pseudo
     CDS             271..366
                     /locus_tag="VYO94_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(619..1239)
                     /locus_tag="VYO94_001584"
     CDS             complement(619..1239)
                     /locus_tag="VYO94_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1760194.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1239..1721)
                     /locus_tag="VYO94_001585"
     CDS             complement(1239..1721)
                     /locus_tag="VYO94_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV1760195.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1721..2563)
                     /locus_tag="VYO94_001586"
     CDS             complement(1721..2563)
                     /locus_tag="VYO94_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV1760196.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2658..3458)
                     /locus_tag="VYO94_001587"
     CDS             complement(2658..3458)
                     /locus_tag="VYO94_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV1760197.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3602..4981
                     /gene="glmU"
                     /locus_tag="VYO94_001588"
     CDS             3602..4981
                     /gene="glmU"
                     /locus_tag="VYO94_001588"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV1760198.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDIEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4991..5536
                     /locus_tag="VYO94_001589"
     CDS             4991..5536
                     /locus_tag="VYO94_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1760199.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5548..5862
                     /locus_tag="VYO94_001590"
     CDS             5548..5862
                     /locus_tag="VYO94_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV1760200.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5879..6571
                     /locus_tag="VYO94_001591"
     CDS             5879..6571
                     /locus_tag="VYO94_001591"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV1760201.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6648..7139
                     /gene="rocS"
                     /locus_tag="VYO94_001592"
     CDS             6648..7139
                     /gene="rocS"
                     /locus_tag="VYO94_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV1760202.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7237..7827
                     /locus_tag="VYO94_001593"
     CDS             7237..7827
                     /locus_tag="VYO94_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV1760203.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7836..9599
                     /locus_tag="VYO94_001594"
     CDS             7836..9599
                     /locus_tag="VYO94_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV1760204.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDTYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            9813..10471
                     /locus_tag="VYO94_001595"
                     /pseudo
     CDS             9813..10471
                     /locus_tag="VYO94_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            10626..10826
                     /locus_tag="VYO94_001596"
     CDS             10626..10826
                     /locus_tag="VYO94_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760205.1"
                     /translation="MVVSASASSTSPQAQEQVDKSELRALSQELDQHLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            10851..11267
                     /locus_tag="VYO94_001597"
     CDS             10851..11267
                     /locus_tag="VYO94_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760206.1"
                     /translation="MKAALDSFKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            11498..12205
                     /gene="ccdA2"
                     /locus_tag="VYO94_001598"
     CDS             11498..12205
                     /gene="ccdA2"
                     /locus_tag="VYO94_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1760207.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            12216..12773
                     /gene="sdbB"
                     /locus_tag="VYO94_001599"
     CDS             12216..12773
                     /gene="sdbB"
                     /locus_tag="VYO94_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV1760208.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            13147..14538
                     /locus_tag="VYO94_001600"
     CDS             13147..14538
                     /locus_tag="VYO94_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV1760209.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYRIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNTKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            14681..15598
                     /gene="adcAII"
                     /locus_tag="VYO94_001601"
     CDS             14681..15598
                     /gene="adcAII"
                     /locus_tag="VYO94_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV1760210.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            15606..>16961
                     /gene="phtD"
                     /locus_tag="VYO94_001602"
     CDS             15606..>16961
                     /gene="phtD"
                     /locus_tag="VYO94_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV1760211.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEERIA
                     RIIPLRYRSNHWVPDSRPEEPSPQPTPKPSPSPQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGTKKTDLPSSDREFY
                     NK"
BASE COUNT         5269 a         3023 c         3564 g         5105 t
ORIGIN      
        1 caccccaaaa gttagatttt ttctgtctaa cttttggggt gtagttcatg tacacctgat
       61 atgatgcatt ttataatttt aaagactttt tgaccagcct cattttttta acttgatact
      121 cagtgaaaag caaagattaa actaggaagc tagctgtagg ctgctcaaag aacagctttg
      181 aggttgcaga taaaacttgt gaggtaacca acatatataa tgtgaagctg acgtggtttg
      241 aatagatttt agaagggtat gagtctggaa gttttaatgg ataatgcaag attccataga
      301 atgggtaagc tagagttctt atgtgaagag tttgggcata aacttttacc ttttcctccc
      361 tactcatctt agtatagaaa agtgaatcta aaatagtaca taactgcttc taaaacattc
      421 ttataaattg atttaaattc tcaaatcata ttattcagtt cttatttcat tttgctctac
      481 aatcctgttg agaagacacg tgttcatatc aaaaaggtat tggcaagttg caataccttt
      541 ttacaaggtt cttttgtctt atttttgttt caactgacta tatctcctat ggttctagtt
      601 cagaaggcta ggctataatt atgattgata agaagtatca ttccaagtat tgagagtgaa
      661 tgtttcaaaa tcatgggttt ctataatggt caggctggca tttgctagac cgccatcttt
      721 acgaagaagt ggttctttat agcctaggag agtacgaaga ctggcagtaa gattggcgcc
      781 gtgtccgaca attagaatac gctcagctgg actatctttt aatgatttga taaattggat
      841 ggtccgctga gttgtactat agagggattc ggctccgaac attcgagtgt caaattgagc
      901 aagatttgaa cgaaaagcct ggatttgttg cgggtaaata gcttccaggg ttgcaatttt
      961 caaaccttct aacttcccaa gttgccattc acggagatta ggaacgattt ctaaagaaca
     1021 gggggtatgg agttgacttt ggataatctc agcagatttg accgctcgag gtaaatcact
     1081 tgaataaatc tgatcaaaag gaatttcctt gagatactga ccaagtcgtt ttagggtttc
     1141 aatggattca ggaagaagag gagaatcacc actagcacct tgaaaacgac cttcttggtt
     1201 ccagagggta cgaccgtggc ggacaaagta gagtttcatt acttgatgtc ctccaaaata
     1261 tctacaaagt ctgcctttac aaagctagcc aagtcttgtg gcgcgacgat aatgctgtgt
     1321 ccgacttcgc ctgcagagac aatcatttga tccaaatcta gagcaatttt atcgataaaa
     1381 atgggataat tgtgtttctg acgaattccg acaggattat tggctccatg aatgtaacca
     1441 gttgtttttt ctaagtcctt ttgtggaatc atgctcactt ttttattgcc agaaatttta
     1501 gctagtttct tttcagacaa gtgctgagtg atagggacaa ttccgataat cggtccggtc
     1561 ttgtctccca aaagcgccaa ggttttgaaa atctgatctc gttcataacc ttgaggaagc
     1621 tctccttcta gggcattgat ttgaatcccc tgatgaggga tagctgcttt agataggatt
     1681 tgttccacca atgttttttt gattttaact ttttttgcca ttatttatat ttatcctcca
     1741 attgactcat ccaaatacca agccagattc ccagcgcaaa gaagaaggcg atgatgacat
     1801 aaccgacaag tgaaagtcct gtgtattgga tactttcagc gtttcctgca tttggaatta
     1861 agatcaaaag ggtacttgat aggacgatac cgatgatgaa atgatagacg cgtgagtggt
     1921 agttgtttaa ggcataatcc atcaattttg aaaaaacgat gagagttgca cctgcaccaa
     1981 ttccaatcgg aaagaaggtt cccaagaaat caaaagtttt aaaaccagtc aacataggag
     2041 catagagtcc caaaatcaaa agtaaatttg atgggctgag gccaggaacc aagacgccaa
     2101 gggccaatag tgcgcctgct aggacaaagt taagaaagct ggcgcttaag gttccaacga
     2161 caaaatttaa ggcatagagt cctaatccag aaatgataaa ggttgtccat aaccaagcta
     2221 aatcaatctt gtctcggtca gattctcgag ttgattcttt gaggaggcta ggaactgtac
     2281 cgataatagc tcccgcaaag ctccataata caaaaacctg ataattttca agcaggtatt
     2341 caatcgggta ggaaaataag ccgattccca gaagcatacc gatggcaact ggaataaagt
     2401 acaaaacatt ttctttaaag tctttaaagg gatgggccag aaagccaatc attcgttcat
     2461 aaattcctaa gattgctgct agaacccctc cggaaattcc cggtaggata aatccaagag
     2521 caattacaat ccctttaata acgcgtgcta accatgagag catatatttc ctccaactat
     2581 ttctatttca aaaaatcctt actatattgt atcacaatca gacacaaaaa gaaaaagcaa
     2641 atgataaaca aatgctttta aggttttaaa aaaagttttc gaaaggtttc ttctttattt
     2701 tttaagggag agataacgtt gatatctaaa tcgtggtcaa agccggcaat ttttccttta
     2761 gatgtgtatt ggtgaatatc ataatctaaa tcagttttag gactgctctc caaaaatcct
     2821 gagtctgagc cgtaggacgg aatccaaaca gaggtaaact tgcctgtatc aatactgtgt
     2881 tcttccatga agtagacacc aacgtagatg ccgatgtttt tagcacctag tgatgctagt
     2941 tttgctcgaa agttttcgac accttcgttc atattagaca tggttttgtc ttccacgtca
     3001 agccaatagt aactagggct gtaaggagag gcagcattgt agaaaacttc ggcagccttt
     3061 tccatttctt ggacactttt tccagctaca taagcgtaga cagcaactgg gacattccgc
     3121 ttttgaagtt cagtgatatg actcttatag gccttgtcta ttccattgat aaatgaagca
     3181 tcattttctt ttgttgtttg agcaccactg tgaacacgaa caatagcacc tgaaatattt
     3241 tgtgagaggg catcgtagtt gatttcctca ggacgctgcc agccagagag gtcaataatc
     3301 ggtttgtcta agtgtttcaa agcctgtgct tcaatctgtg ctatattgga ttttgtttta
     3361 aacgattggt tgtcattaag tgggcgattg atgattaaaa tgaacatcat aatcccaaaa
     3421 aaactaaata aaataagtgg atgaatttgt tttctcatat cttataattc taccctaaaa
     3481 atcaaaaaaa atcaaaaaaa tgggttaagg aagagacttt agagcatttt ttcattcaag
     3541 agtgcggaat gatttgaaat atggtataat aaaagggaat ttctacagaa aagagaagat
     3601 tatgtcaaat tttgccatta ttttagcagc gggtaaaggg actcgcatga aatctgattt
     3661 gccaaaagtt ttgcacaagg ttgcgggtat ttctatgttg gaacatgttt tccgtagtgt
     3721 gggagctatc caacctgaaa agacagtaac agttgtagga cacaaggcag aattggttga
     3781 ggaggtcttg gctggacaga cagaatttgt gactcaatct gaacagttgg gaactggtca
     3841 tgcagttatg atgacagaac ctatcttaga aggtttgtca ggacacacct tggtcattgc
     3901 aggagatacc cctttaatca ctggtgaaag cttgaaaaac ttgattgatt tccatatcaa
     3961 tcataaaaat gtggccacta tcttgactgc tgaaacggat aatccttttg gctatggacg
     4021 aattgttcgt aatgacaatg ctgaggttct tcgtattgtt gagcagaagg atgctacaga
     4081 ttttgaaaag caaatcaagg aaatcaacac tggaacatac gtctttgaca acgagcgttt
     4141 gtttgaggct ttgaaaaata tcaataccaa taacgctcaa ggcgaatact atattacaga
     4201 cgtcattggt attttccgtg aaactggtga aaaagttggc gcttatactt tgaaagattt
     4261 tgatgaaagt cttggggtaa atgaccgtgt ggcgcttgcg acagctgagt cagttatgcg
     4321 tcgtcgcatc aatcataaac acatggtcaa cggtgttagc tttgtcaatc cagaagcaac
     4381 ttatatcgat attgatattg agattgctcc ggaagttcaa atcgaagcca atgttacctt
     4441 gaaagggcaa acgaaaattg gtgctgagac tgttttgaca aacggtactt atgtagtgga
     4501 cagcactatc ggagcaggag cggttattac caattctatg attgaggaaa gtagtgttgc
     4561 agacggtgtg acagtcggtc cttatgctca cattcgtcca aattcaagtc tgggtgccca
     4621 agttcatatt ggtaactttg ttgaggtgaa aggatcttca atcggtgaga ataccaaggc
     4681 tggtcatttg acttatatcg gaaactgtga agtgggaagc aacgttaatt tcggtgctgg
     4741 aactattaca gtcaactatg acggcaaaaa caaatacaag acagtcattg gagacaatgt
     4801 ctttgttggt tcaaattcaa ccattattgc accagtagaa cttggtgaca attccctcgt
     4861 tggtgctggt tcaactatta ctaaagacgt gccagcagat gctattgcta ttggtcgcgg
     4921 tcgtcagatc aataaagacg aatatgcaac acgtcttcct catcatccta agaaccagta
     4981 ggagcctatc atggagtttg aagaaaaaac gcttagccga aaagaaatct atcaaggacc
     5041 aatatttaaa ctggtccaag atcaggttga attaccagaa ggcaagggaa ctgcccaacg
     5101 ggatttgatt ttccacaatg gggctgtctg tgttttagca gtaacggatg aacaaaaact
     5161 tatcttggtc aagcagtacc gcaaagctat cgaggcagtc tcttacgaaa ttccagccgg
     5221 aaaattggag gtaggagaaa acacagcccc tgtcgcagct gcccttcgtg aattagagga
     5281 agaaacagcc tatacaggga aattagaact cttgtacgat ttttattcag ctattggctt
     5341 ttgtaatgag aagttaaaac tatatttagc aagcgatttg acaaaagtgg aaaatccgcg
     5401 tccgcaggat gaggatgaaa ccttggaagt ccttgaagtg agcttagaag aagcgaaaga
     5461 attaatccaa tcaggtcata tctgtgatgc caagacaatt atggctgttc agtattggga
     5521 gttgcagaaa aaatagagga ggtcagtatg ggtaaatctt tattaacgga tgaaatgatt
     5581 gaaagagcta atagaggcga aaaaatttca ggtcctcctt tgctagatga taatgaggaa
     5641 actaagattt taccaacctc ttcttcccgt tttggttatg ccaatcctaa ggatcatggt
     5701 tttagccagg aaaccttgaa gattcaggtc gaaccatcta ttcataaaag ccgtcgtatt
     5761 gaaaatacca agagaaatgt cttcaattct aagttgaata aaatcttatt tgcggtcatc
     5821 tttctcttga ttttgcttgt tttagcaatg aaacttttgt aatagaaaag gaattgaaat
     5881 gaaaatagga attattgctg ctatgccaga agaactggct tatctggtcc agcatttaga
     5941 taatacccag gagcaagttg ttttggggaa tacctatcat acaggaacca ttgcttctca
     6001 tgaagtcgtt cttgtagaaa gtggaattgg taaggtcatg tctgctatga gtgtggcgat
     6061 tttggctgat catttccagg tggatgccct tattaatacg ggttcagctg gggcagtagc
     6121 agaaggtatc gctgttgggg atgtcgtgat tgctgacaaa ttagcctatc atgacgtgga
     6181 tgtcacagct tttggctatg cttatggaca aatggcgcaa caaccgcttt atttcgaatc
     6241 agacaaaacc tttgttgctc aaatccaaga gagtttatct caattggacc aaaactggca
     6301 tcttggtttg attgctacag gagatagttt tgttgcagga aatgacaaga tagaagcgat
     6361 taagtcccat ttcccagaag ttttagccgt ggagatggag ggggcagcta ttgctcaagc
     6421 agcgcatgcc ctcaatctcc cagtcttagt catcagagct atgagtgaca atgccaacca
     6481 tgaagcaaac atcttttttg atgagtttat tatcgaagct ggacgtcgct ctgcccaagt
     6541 cttgttgacc tttttgaagg ctttagatta agcggaaatt tgacagtttt tctagcttat
     6601 gataagattt aagtaaagaa aagctagaaa acgtttcaga ggatattatg agtattgaaa
     6661 tgaccgtcag tgagattgca gaggtcttag gattatctcg ccaagcaatc aataaccgtg
     6721 tcaaagaatt accagaagaa gacacagata aaaatgacaa aggggtaaca gttgttacca
     6781 gaagtggctt gattaagcta gaagaaatct ataaaaaaac gatttttgaa gatgagcctg
     6841 tcagtgaaga tgtcaaacaa cgtgaactga tggagattct agtggatgag aagaatgcag
     6901 aaattcttcg tctttatgaa caattaaaag ccaaggatcg tcagttatca gaaaaagacg
     6961 agcagatgcg tatcaaagac cgtcagattg ctgagaaaga caaacaatta gatcagcaac
     7021 aacaattgac ccttcaagcc atgaaggatc aagaaaatct taagctagag ctggaccaag
     7081 caaaagaaga agtccaatcc actaaaaaag gcttttttgc tcgtttattt ggaggataat
     7141 caaggagctg tttaggttaa atgctaacct gatggcttct tttgtttgtg aatagtatag
     7201 ttgattagaa cagagacagt agaggagagg tacagaatgg aacgattaga agattacatt
     7261 gcttttgatt tagaatttaa tcagcacgaa ggacaaacac acttgattca agtatcggca
     7321 gtgcgtttta gagatggtcg ggaaatcgat gcctatgatt cctatgttca taccagcgtc
     7381 cctctaaaaa gctttatcaa tggtttgacc gggattacag ctgagacctt aaaagatgct
     7441 cctccagttg agaaagtctt agaagaattc caagagtttg tgggttcttt gctgatgata
     7501 ggctacaatg ctgctaaaag tgatttacct attttagcag agcatggttt agactatagc
     7561 caacagtaca aggtggattt gtatgatgaa gcttttgaac gtcggagttc agatttacat
     7621 ggtattgcca atctcaaatt gcaaactgtt gcctcatttc ttggatttca aggtcagtct
     7681 cataatagtt tagaggatgc tcggatgacg gcgcgtgttt acgaatcctt cttagagtcg
     7741 gatcaagcta gggaattgtt agagacagaa agtagcttat caaacaatcc ttttggtggc
     7801 ttggacttgt ctcaattatt tgactaggag tgcctatgaa acctgaaaaa cctaaaaaat
     7861 tgggtcttaa acagatttac ctcaatcttg ataaaatcct ctttctattt ttcttgattt
     7921 ttatgatagt ggagtatttg tgggtaccat tcaattcatg gttggctagc ttcttattag
     7981 atcagacagg ttatcttttt atttcctata acaatgtctt agccatcctt actcattctc
     8041 cattgattag tctagctttt ttagccttga ttgtaattaa ccttctggtt gcttattttc
     8101 aaataggact cctctttatt ggcgctcgtc atctcctcta taatgaaaag cgaaggctaa
     8161 ttgagtatat ccgcaaggtt ttccatgaaa gttttggatt tatgaaaaag ctaacttgcg
     8221 ctaaagcctt gtttatcttt ttctatatag ctatgctttt tccttttata cggaaaatgc
     8281 tgaagattta ttatcttaat aaaatcgtca ttccagagtt tatccaagct tatttagaag
     8341 atacatattg gatgtggtgg ctgagcatcc tacttctatc tcttatcttt ctctatgtct
     8401 ctgtcagatt gatgtttgcc cttccgaaga ttgtatatga tcagctgact gttcgagaag
     8461 cagtgatgtt tagcttggag aaaaccaaga agagagttac tttttatgct tggaatttat
     8521 tttacatctt gctcaaagca catttattat tttatcttcc tttgattcct ttattattgg
     8581 ctcaaacttt ggtagatgat atcactcaga gagagtctct gattcttggt attttgaatt
     8641 ttgtcgtgat taaaaatctc tattatatgg ctctgactta ttttttggtt aaatttgttt
     8701 catttttgac aggaaaggag ctggatatgc ttcctaggag agaaaaagat cacatcgtgc
     8761 gatggggtgt catgacttgt gccagtcttt tctttgcctt agaaggttat atttatctgg
     8821 aggctcccat ggttcatcta cctcaactta tttctcaccg aggggtttcc aatgcaaatg
     8881 ggattcaaaa tacagtagag tccttggaaa ctacagcaca actcaaacca gacttggtgg
     8941 agacggacgt gcaggaaaca aaagatgggc agtttgtcat gatgcatgat gctaacttga
     9001 aaaatctagc aggtatcaat aaaagtcctc aagacttaaa cttggaggag cttaaaggga
     9061 ttgatatttt tgaaaatggc taccagacta aaatttcaag ctttgaagat tatctcagtc
     9121 gagccaacga acttggtcaa aaattactaa ttgaaattaa aaccagtaaa aaagatagtc
     9181 cagacatgat gaaccgcttt ttagcccgtt atgctgcaaa gctcaagatt tatggacatc
     9241 aaatccagtc tttagactac catgttgtcg aaaaagtaag acagtatgat gccgaactgc
     9301 cagtttattt catcatgccc tacaattctg tctttcctaa aacaagagcg acaggatata
     9361 ctatggagta ctcaaccttg gatgaatatt ttgtaagcaa actatggaca acggatcaga
     9421 aactttatgt ctggactgtc aatgattcag aagctatcag caaatctctt cacttaggag
     9481 tagatggagt gattacagat gatttggaaa aagttcagcg ggaaatagaa gtagcccaag
     9541 aagatccaga atatacggat ttgctcttga aaaaagcatt ggaattcttt gaattttagt
     9601 aataaaaaag aggaacggtt gttcctccca tgataggtaa gtattcttgt gaatgcttgc
     9661 ttttttgtgg ttgcaatccg tttacgagaa ttgtttgtat tgttcttgtt tcaatttact
     9721 ttatagtgct ttgaagttgg aatgctacac tataacttct aaaatatagt aaaatgaacc
     9781 aaaaatagta cacaatgtgg tataatcttt ttatggcata ttcaatagat tttcgtaaaa
     9841 aagttctctc ttattgtgag cgaacaggta gtataacaga agcatcacac gttttccaaa
     9901 tctcacgtaa taccatttat ggctggttaa agctaaaaga gaaaacagga gagctaaacc
     9961 accaagtaaa aggaacaaaa ccaagaaaag ttgatagaga tagacttaaa aactatctta
    10021 ctgataatcc agacgcttat ttgactgaaa tagcttctga atttggctgt catccaacta
    10081 ccatccacta tgcgctcaaa gctatgggct acactcgaaa aaaagaacca cacctactat
    10141 gaacaaaacc cagaaaaagt agccttattt cttaagaatt ttaatagttt aaagcaccta
    10201 gcacctgttt agattgacga aacaggattt gatacttatt tttatcgaga atatggtcgc
    10261 tcattaaaag gtcagttaag aagaggcaaa gtatctggaa gaagatatca gaggatttct
    10321 ttggttgcag gtctaacaaa tgaatggtga gttaatcgct ccaatgactt acgaagagac
    10381 gatgacgagc gacttttttg aagcttggtt tcagaagttt ctcttaccaa cattaaccac
    10441 accatcggtt attatattaa aacgaaataa gaataggaca aatcgatcag gacagtaaaa
    10501 tcgaattcta acaatgtttt agaagtccat atgtactatt ctagtttcaa tataccataa
    10561 ctgctcctag tcaacctgca agtcctgtcc cagctccaag ctcagctccg actcaagatc
    10621 ctagagtggt agtaagcgct tcggctagct caacgagccc acaagctcaa gagcaagttg
    10681 acaagtctga acttcgtgcc ttgagtcaag agttagacca acacttgaaa gctttggcaa
    10741 cagtatctga tccgaaaatc gatgcaacca aggctgtcct cctagatgct caaaaagctc
    10801 cggaagatag tgccttgaca gagtaaggtc tgcatactgc agtagagtct gtgaaggctg
    10861 ccttggactc tttcaaagat gtgaaagcaa atgctagcga cagcaagcct gcacaggaca
    10921 agaaggatgc aaaacaagga acggaagata gtaaggattc agataagatg actgaaacaa
    10981 actcagttcc ggcaggagtg attgtggtca gtctacttgc cctcctaggc gtgattgcct
    11041 tctggctgat tcgccgtaag aaagagtcag aaatccagca attaagcacg gaattgatca
    11101 aggttctagg acagctagat gcagaaaaag cggataaaaa agtccttgcc aaagcccaaa
    11161 accttctcca agaaaccctt gatttcgtga aagaagaaaa tggctcagca gagacagaaa
    11221 ctaaactagt agaggagctt aaagcaatcc ttgacaaact caagtaaaac atgatttatg
    11281 aaatgtcaga cctaaaagac attttcgttc acaaaagcag cgatgagtaa tccttgtcgt
    11341 tgctttttgg ctattttggg ggataagatc cgccttgact agcaaaagaa aagattggtc
    11401 caatagtgcc cgatacgatt ttgcgtagca gaaagcttac aaataaaatt gaatatagta
    11461 aaataggatt agaattatta agaaagttgg ttctttattg gaaacgatag tatttttaat
    11521 ctctgttttt ctagcaggtg ttttatcctt tttttctcct tgtatttttc ctcttctgcc
    11581 agtctatgct gggattttat tggatgatca agaaagtgca aaaagctttt ctttgtttgg
    11641 gagaaaggtt ctctggtcag gcttgattcg aacactttgc tttatcgctg gtatctctct
    11701 cattttcttt attctaggct ttggtgctgg ttactttggt catattctct atgcaaattg
    11761 gtttcgatat gtcatgggag ctattattat cattttgggt cttcaccaga tggaaatttt
    11821 tcatttgaag aaattagaag ttcaaaaaag ttttaccttt aaaaaatcag attctaatcg
    11881 ttattggtca gcttttttac ttggtattac ctttagcttt ggttggacac cttgtattgg
    11941 tccagtttta agttctgttt tagcacttgc ggcttctgga ggcaatggtg cttggcaagg
    12001 agcgatttat actctcattt acactctggg catggccctt cctttcttgg tcttggcact
    12061 agcttcaggt ctagtcatgc catattttag taaaatcaag cgtcatatga tgctactaaa
    12121 gaaaattggt ggtttcctca ttgttttaat gggaattttg ttactattag gacaagtaaa
    12181 tgttctagct ggaatttttg aataaaggag gacaaatgaa aaaagtaatg tttgctggct
    12241 taagtctctt gtcattagtt gtattgatgg cctgtggtga ggaagaaact aaaaagactc
    12301 aagcagcaca acagccaaaa caacaaacga ctgtacaaca aattgctgtt ggaaaagatg
    12361 ctccagactt tacattgcaa tccatggatg gcaaagaagt taagttatct gattttaagg
    12421 gtaaaaaggt ttacttgaag ttttgggctt catggtgtgg tccatgcaag aaaagtatgc
    12481 cagagttgat ggaactagcg gcgaaaccag atcgtgattt cgaaattctt actgtcattg
    12541 caccaggaat tcaaggtgaa aaaactgttg agcaattccc acaatggttc caggaacaag
    12601 gatataagga tatcccagtt ctttatgata ccaaagcaac caccttccaa gcttatcaaa
    12661 ttcgaagcat tcctacagaa tatttaattg atagccaagg aaagattgga aagattcaat
    12721 ttggtgctat cagtaatgcg gatgcagaag cagcatttaa agaaatgaac tagaatcgat
    12781 aaaatctgat tacaagatgt agtcagattt tggtaacttc taaaactaac ttccagtttc
    12841 ccacaaccta gcttttagta tgagaaaaac gcgtgacatc agtggaaatc cgtcttagat
    12901 taacttccac tggttttctt tttcttgata tataagggtt caaaagcgaa aagactcaga
    12961 aaaagtgcac gacaaatagc cctaaaacag agtcgtctga gactaacttc cagttttggg
    13021 agagagatgg aagttacttt gagaagttac ggtagtcaga tttttttaga aaaatatttt
    13081 ataaatattc acatatctcc tatatttatg gtaaaataga atcatcagtt tattttggag
    13141 tcaaagatga atatatttag aacaaagaat gttagtttag ataaaacaga gatgcatagg
    13201 catttgaagt tatgggattt gattttgctg ggtattggag ccatggtagg gacaggtgtt
    13261 tttacaatca caggtactgc agctgctaca cttgctggtc cagcactagt gatttcaatc
    13321 gttatttctg ccttgtgtgt gggattatca gccctctttt ttgcagaatt tgcctcgcga
    13381 gtacccgcta caggaggtgc ctatagttac ctctatgcta tcttaggaga attccctgcc
    13441 tggttggctg gttggttaac catgatggag ttcatgacag ccatatcagg cgtagcttcg
    13501 ggttgggcag cttattttaa aggcttgctc tctcaataca ggatagcctt tcctcaggct
    13561 ttaaatggta cctttaatcc tcaagcaggg acatttgttg atttattgcc tattcttgtc
    13621 ttggtcttgg tgacttcgct tgttttacta aataccaagg cagccttacg ctttaattcg
    13681 attctagtta ttttgaaatt ttccgcttta gctctctttg ttttagtagg aatttggaat
    13741 attaagtttg ataattggag caattttgct ccttacggtt ttggacaaat ctatggagct
    13801 agcactggta ttatggctgg tgcgtccttg atgttcttcg gttttttggg atttgaatcc
    13861 atctctatgg ctgtagatga agtcaagact cctcaaaaaa atattcctag agggattgtc
    13921 ttatcgcttt ctatcgtaac cattctctat gccttggtga cccttgtttt gactggtgtg
    13981 gttcactata gtcatttaaa tgtcgatgat gccgttgcct ttgcccttcg tagtgttggg
    14041 attagttggg cagccaacta tgtgtcatta gtggctatct tgaccttgat tacagtttgt
    14101 atttcgatga cctatgccct atcgcgtatg atttacagtt tagcacgtga cggcttagtg
    14161 cctgctgcct ttaaggaact gacgaagact agcaagatac caaagaatgc tactatcttg
    14221 acaggtctag cttcagcagt agcagcagga atgttcccac tagccagtat tgcagccttt
    14281 ttaaatattt gtaccttagc ctacttgatc atgttggctt atggtctgat tcgcttacgg
    14341 aaagaaaaag gaatgcccaa agctggggaa tttaaaacac cattggtacc tctgttacca
    14401 attttatcga tcatcatttg tttatccttc atgttacagt ataatatgaa tacctggatt
    14461 gctttcctag ttgcgttgtt agtaggaagt attatttact tcacttatgg ctataagcat
    14521 tctaccatag aagaataaag tgaaagtcta ttgagttgtt gacactcagc agatttttat
    14581 atgtgaaaga aatttcaaat tttttctaaa aatatcttga cagattaaat tttcaggagt
    14641 agaatattta ctagttaatt aaatggttaa ggagttgttc atgaagaaac aaaatttatt
    14701 tttagtcctg ttaagtgtct ttcttttgtg cttgggggct tgtggtcaaa aggaaagtca
    14761 gacaggaaag gggatgaaaa ttgtgaccag tttttatcct atctacgcta tggttaagga
    14821 agtatctggt gacttgaatg atgttcggat gattcagtca agtagtggta ttcactcctt
    14881 tgaaccttcg gcaaatgata tcgcagccat ctatgatgca gatgtctttg tttaccattc
    14941 tcatacactc gaatcttggg caggaagtct ggatccaaat ctaaaaaaat ccaaagtgaa
    15001 ggtcttagag gcttctgagg gaatgacctt ggaacgtgtc cctggactag aggatgtgga
    15061 agcaggggat ggagttgatg aaaaaacgct ctatgaccct cacacatggc tagatcctga
    15121 aaaagctgga gaagaagccc aaattatcgc tgataaactt tcagaggtgg atagtgagca
    15181 taaagagact tatcaaaaaa atgcgcaagc ctttatcaaa aaagctcagg aattgactaa
    15241 gaaattccaa ccaaaatttg aaaaagcgac tcagaaaaca tttgtaacac aacatacagc
    15301 cttttcttat ctagcgaaga gatttgggct taatcaactt ggtattgcag gtatctctcc
    15361 tgaacaagaa ccaagtccac gacaactaac agaaattcag gaatttgtta agacctataa
    15421 ggttaaaacg atttttacag aaagtaacgc ttcttcaaaa gtagctgaaa ctcttgtcaa
    15481 atcaacaggt gtaggtctta aaactctgaa tcctttagag tcagacccac aaaatgacaa
    15541 gacctattta gaaaatcttg aagaaaatat gagtattcta gcagaagaat taaagtgagg
    15601 aaagaatgaa aatcaataaa aaatatctag caggttcagt ggcagtcctt gccctaagtg
    15661 tttgttccta tgaacttggt cgtcaccaag ctggtcaggt taagaaagag tctaatcgag
    15721 tttcttatat agatggtgat caggctggtc aaaaggcaga aaacttgaca ccagatgaag
    15781 tcagtaagag ggaggggatc aacgccgaac aaatcgtcat caagattacg gatcaaggtt
    15841 atgtgacctc tcatggagac cattatcatt actataatgg caaggttcct tatgatgcca
    15901 tcatcagtga agaacttctc atgaaagatc cgaattatca gttgaaggat tcagacattg
    15961 tcaatgaaat caagggtggc tatgtgatta aggtagacgg aaaatactat gtttacctta
    16021 aagatgcggc ccatgcggac aatattcgga caaaagaaga gattaaacgt cagaagcagg
    16081 aacgcagtca taatcataac tcaagagcag ataatgctgt tgctgcagcc agagcccaag
    16141 gacgctatac aacggatgat ggttatatct tcaatgcatc tgatatcatc gaagatacgg
    16201 gcgatgccta tatcgttcct catggcaatc acttccacta tattcctaag agtgatttat
    16261 ctgccagtga attagctgct gcccaagcct attggaatgg gaagcaggga tctcgtcctt
    16321 cttcaagttc tagtcataat gcaaatccag ctcaaccaag attgtcagag aaccacaatc
    16381 tgactgtcac tccaacttat catcaaaatc aaggggaaaa catttcaagc cttttacgtg
    16441 aattgtatgc taaaccctta tcagaacgcc atgtggaatc tgatggcctt attttcgacc
    16501 cagcgcaaat cacaagtcga accgccagag gtgtagctgt ccctcatggt aaccattacc
    16561 actttatccc ttatgaacaa atgtctgaat tggaagaacg aattgctcgt attattcccc
    16621 ttcgttatcg ttcaaaccat tgggtaccag attcaagacc agaagaacca agtccacaac
    16681 cgactccgaa acctagtcca agtccgcaac ctgcaccaaa tcctcaacca gctccaagca
    16741 atccaattga tgagaaattg gtcaaagaag ctgttcgaaa agtaggcgat ggttatgtct
    16801 ttgaggagaa tggagtttct cgttatatcc cagccaagga tctttcagca gaaacagcag
    16861 caggcattga tagcaaactg gccaagcagg aaagtttatc tcataagcta ggaactaaga
    16921 aaactgacct cccatctagt gatcgagaat tttacaataa g
//
LOCUS       DAVMAH010000049        16628 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVMAH010000049 DAVMAH010000000
VERSION     DAVMAH010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16628
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.049"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..1112
                     /gene="lytB"
                     /locus_tag="VYO94_001603"
     CDS             <1..1112
                     /gene="lytB"
                     /locus_tag="VYO94_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV1760212.1"
                     /translation="GKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSD
                     GKIAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKTTNENAAYYQV
                     VPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDA
                     SKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFL
                     FKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALES
                     NWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLG
                     NKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(1173..2828)
                     /gene="pavA"
                     /locus_tag="VYO94_001604"
     CDS             complement(1173..2828)
                     /gene="pavA"
                     /locus_tag="VYO94_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV1760213.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTTNELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2933..3430
                     /gene="ybeY"
                     /locus_tag="VYO94_001605"
     CDS             2933..3430
                     /gene="ybeY"
                     /locus_tag="VYO94_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV1760214.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRNTDRPTDVISLEYKPELEIAFDEEDLLENSELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3411..3806
                     /locus_tag="VYO94_001606"
     CDS             3411..3806
                     /locus_tag="VYO94_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV1760215.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3823..4722
                     /gene="era"
                     /locus_tag="VYO94_001607"
     CDS             3823..4722
                     /gene="era"
                     /locus_tag="VYO94_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV1760216.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4771..5595
                     /gene="mutM"
                     /locus_tag="VYO94_001608"
     CDS             4771..5595
                     /gene="mutM"
                     /locus_tag="VYO94_001608"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV1760217.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDVYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5595..6200
                     /locus_tag="VYO94_001609"
     CDS             5595..6200
                     /locus_tag="VYO94_001609"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV1760218.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6187..7386
                     /locus_tag="VYO94_001610"
     CDS             6187..7386
                     /locus_tag="VYO94_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HEV1760219.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7386..7535
                     /gene="rpmG"
                     /locus_tag="VYO94_001611"
     CDS             7386..7535
                     /gene="rpmG"
                     /locus_tag="VYO94_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1760220.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7575..7808
                     /gene="secG"
                     /locus_tag="VYO94_001612"
     CDS             7575..7808
                     /gene="secG"
                     /locus_tag="VYO94_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV1760221.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7910..10264
                     /gene="rnr"
                     /locus_tag="VYO94_001613"
     CDS             7910..10264
                     /gene="rnr"
                     /locus_tag="VYO94_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV1760222.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLEFGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRDSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10227..10694
                     /gene="smpB"
                     /locus_tag="VYO94_001614"
     CDS             10227..10694
                     /gene="smpB"
                     /locus_tag="VYO94_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV1760223.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQEIKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10710..11570
                     /gene="tehB"
                     /locus_tag="VYO94_001615"
     CDS             10710..11570
                     /gene="tehB"
                     /locus_tag="VYO94_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV1760224.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11643..12596
                     /gene="coiA"
                     /locus_tag="VYO94_001616"
     CDS             11643..12596
                     /gene="coiA"
                     /locus_tag="VYO94_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV1760225.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12615..14417
                     /gene="pepF"
                     /locus_tag="VYO94_001617"
     CDS             12615..14417
                     /gene="pepF"
                     /locus_tag="VYO94_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1760226.1"
                     /translation="MVLQRNEINEKDTWELSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSFVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14419..15132
                     /locus_tag="VYO94_001618"
     CDS             14419..15132
                     /locus_tag="VYO94_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV1760227.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGSLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDVTLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            15199..16140
                     /gene="prsA"
                     /locus_tag="VYO94_001619"
     CDS             15199..16140
                     /gene="prsA"
                     /locus_tag="VYO94_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV1760228.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16256..16597)
                     /locus_tag="VYO94_001620"
                     /pseudo
     CDS             complement(16256..16597)
                     /locus_tag="VYO94_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         5003 a         3105 c         3726 g         4794 t
ORIGIN      
        1 atgggaaaat agctgaaaaa gaatgggtct acgattctca tagtcaagct tggtactact
       61 tcaaatccgg tggttacatg acagccaatg aatggatttg ggataaggaa tcttggtttt
      121 acctcaaatc tgatgggaaa atagctgaaa aagaatgggt ctacgattct catagtcaag
      181 cttggtacta cttcaaatct ggtggctaca tggcgaaaaa tgagacagta gatggttatc
      241 agcttggaag cgatggtaaa tggcttggag gaaaaactac aaatgaaaat gctgcttact
      301 atcaagtagt gcctgttaca gccaatgttt atgattcaga tggtgaaaag ctttcctata
      361 tatcgcaagg tagtgtcgta tggctagata aggatagaaa aagtgatgac aagcgcttgg
      421 ctattactat ttctggtttg tcaggctata tgaaaacaga agatttacaa gcgctagatg
      481 ctagtaagga ctttatccct tattatgaga gtgatggcca ccgtttttat cactatgtgg
      541 ctcagaatgc tagtatccca gtagcttctc atctttctga tatggaagta ggcaagaaat
      601 attattcggc agatggcctg cattttgatg gttttaagct tgagaatccc ttccttttca
      661 aagatttaac agaggctaca aactacagtg ctgaagaatt ggataaggta tttagtttgc
      721 taaacattaa caatagcctt ttggagaaca agggcgctac ttttaaggaa gccgaagaac
      781 attaccatat caatgctctt tatctccttg cccatagtgc cctagaaagt aactggggaa
      841 gaagtaaaat tgccaaagat aagaataatt tctttggcat tacagcctat gatacgaccc
      901 cttacctttc tgctaagaca tttgatgatg tggataaggg aattttaggt gcaaccaagt
      961 ggattaagga aaattatatc gataggggaa gaactttcct tggaaacaag gcttctggta
     1021 tgaatgtgga atatgcttca gacccttatt ggggcgaaaa aattgctagt gtgatgatga
     1081 aaatcaatga gaagctaggt ggcaaagatt agtactataa gtgaatatga tttgagtgaa
     1141 tagtaagtta aaaatcctga tttcaagtaa aatcaggatt ttttcatgga tgcaattttt
     1201 ttggagtctg gtgtgacgcg gagggtcttt tgtcctgtgt aagtgacaaa gccgggtttt
     1261 ccaccagttg gtttattgag ttttttgact tcaatcatat ctacctgcac cagattcgac
     1321 aggcgccctt gagagaagta ggcagctaac tctgctgcgt ctgtcttgac tgcatcagat
     1381 gggtcaagat ttcctgagat gacaacatgg cttccaggaa tgtccttagc atggaaccaa
     1441 agttcctcct tgcgggccat tttaaaggtc aattcctcat tttgaagatt gtttcgtccg
     1501 acatagatga tggttttgcc atcgcttgct agatattgtt ctagtttttt gcgtttctgg
     1561 attttctccc gttgtcttct gcggataaaa cctgtttgaa tcaattcttc acggatttca
     1621 gcgatttctt ccagtccagc ttggttgagg acggtttcta cactttccag atagagaata
     1681 gtggctttgg tttcttcaat caaatcagtc aagtatttga cagcttcttt gagtttctga
     1741 taccgtttaa aatagcgttg ggcattctgg ttgggagtca gagccttatc aagcgcaatc
     1801 atgataggtt ggttggtata gtagttgtct aggataacct ggtcttggtc gttaggcact
     1861 tggtggagga aggttgtcag caattctcct ttttgacgaa attcttcagc gttgtctgtc
     1921 gccagtaact ctttttcctg ttttttgagt ttgtgtcggt ttttctgaag ttcattttca
     1981 acacgacgaa tcagttcact ggcctgctgt ttgacgcggt cgcgctcagc cttatcctta
     2041 tagtaggtgt ccaacaaatc agaaagattt gcaaaaggct ctcccacctg atttgcaaaa
     2101 ggaactggac tgaaggaagt ctcagtcaag catggcttgg tttcttgatt gaaaaaattt
     2161 cggaaagcgg aaagtttttc actaaccagt atcctttcca attcatttgt cgtatcgcgt
     2221 cccagacctt gaaagaggct ttgaagattt tttgctgtta gttcttgggt ttgcaggatt
     2281 tcaaagagct tttcatcctt gatagtaaaa ggattgagag attttgtact tggcggagcg
     2341 atataggtcg atcctggaag taaggtgcgg tagctatttt gtgaaaagcc gacgtgtttg
     2401 ataacttcga ggattttatg actgctttta tcgaccagta gaatattact gtgtttcccc
     2461 ataatttcga taatcaaggt agcctggata tggtctccaa tctcgttttt attggaaact
     2521 gtaatttcca caatacggtc attttccact tgctcaatcg actcaatcag ggccccctgc
     2581 aaatactttc tcaaaaccat gataaaggta gaaggttgag ctggattttc aaaagtcgtt
     2641 tgggtcagct gaatgcgtcc aaaaactgga tgggcagaaa ggagcaggcg atggctttgg
     2701 cgattgctgc ggatttgcaa gaccaactct tgttcaaaag gctgattgat tttctggatg
     2761 cgaccattca ctaattcgct tcgcaattcc tcaactatgt ggtgtaaaaa aaatccgtca
     2821 aatgacatcg ttctctcctt gtgattgtat tccatagtat tatatcaaaa aggtagaata
     2881 aaatcatgga aatgtggtat aataaagcca agtaaagaga aacgagaagc acatgtatat
     2941 tgaaatggta gatgaaactg gtcaagtttc aaaagaaatg ttgcaacaaa cccaagaaat
     3001 tttggaattt gcagcccaaa aattaggaaa agaagacaag gagatggcag tcacttttgt
     3061 gaccaatgag cgtagtcatg aacttaatct ggagtaccgt aacaccgacc gtccgacaga
     3121 tgtcatcagc cttgagtata aaccagaatt ggaaattgcc tttgacgaag aggatttgct
     3181 tgaaaattca gaattggcag agatgatgtc tgagtttgat gcctatattg gggaattgtt
     3241 catctctatc gataaggctc atgagcaggc cgaagaatat ggtcacagct ttgagcgtga
     3301 gatgggcttc ttggcagtac acggcttttt acatattaac ggctatgatc actacactcc
     3361 ggaagaagaa gcggagatgt tcggtttaca agaagaaatt ttgacagcct atggactcac
     3421 aagacaataa acgaaaatgg aaaaatcgtg acttgatatc cagtttagaa tttgctttga
     3481 caggtatttt tactgctatc aaggaagaac gcaatatgcg aaaacacgca gtgacggctc
     3541 tagtggtcat ccttgcaggt tttgtttttc aggtgtcacg aatcgaatgg ctctttctcc
     3601 tattgagtat tttcttggta gtagcctttg agattatcaa ctctgctatt gaaaatgtgg
     3661 tggatttggc cagtcactat cacttttcca tgctggctaa aaatgccaag gatatggcgg
     3721 ccggcgcggt attagtggtt tctcttttcg cagccttaac aggcgcattg atttttctcc
     3781 cacgaatctg ggatttatta ttttaaacag taagaggaaa ttatgacttt taaatcaggc
     3841 tttgtagcca ttttaggacg tcccaatgtt gggaagtcaa cctttttaaa tcacgttatg
     3901 gggcaaaaga ttgccatcat gagtgacaag gcgcagacaa cgcgcaataa aatcatggga
     3961 atttacacga ctgataagga gcaaattgtc tttatcgaca caccagggat tcacaagcct
     4021 aaaacagctc tcggagattt catggttgag tctgcctaca gtacccttcg cgaagtggac
     4081 accgttcttt tcatggtgcc tgctgatgaa gcgcgtggta agggggacga tatgattatc
     4141 gagcgtctca aggctgccaa ggttcctgtg attttggtgg tgaataaaat cgataaggtc
     4201 catccagacc agctcttgtc tcagattgat gacttccgta atcaaatgga ctttaaggaa
     4261 attgttccaa tctcagccct tcagggaaat aacgtgtctc gtctagtgga tattttgagt
     4321 gaaaatctgg atgaaggttt ccaatatttc ccgtctgatc aaatcacaga ccatccagaa
     4381 cgtttcttgg tttcagaaat ggttcgcgag aaagtcttgc acctaactcg tgaagagatt
     4441 ccgcattctg tagcagtagt tgttgactct atgaaacgag acgaagagac agacaaggtt
     4501 cacatccgtg caaccatcat ggtcgagcgc gatagccaaa aagggattat catcggtaaa
     4561 ggtggcgcta tgcttaagaa aatcggtagc atggcccgtc gtgatatcga actcatgcta
     4621 ggagacaagg tcttcctaga aacctgggtc aaggtcaaga aaaactggcg cgataaaaag
     4681 ctagatttgg ctgactttgg ctataatgaa agagaatact aagtagaggt aggctcatgc
     4741 ctgcttcttg tttttacaga aggaggactt atgcctgaat tacctgaggt tgaaaccgtt
     4801 tgtcgtggct tagaaaaatt gattatagga aagaagattt cgagtataga aattcgctac
     4861 cccaagatga ttaagacgga tttggaagag tttcaaaggg aattgcctag tcagattatc
     4921 gagtcaatgg gacgtcgtgg aaaatatttg cttttttatc tgacagacaa ggtcttgatt
     4981 tcccatttgc ggatggaggg caagtatttt tactatccag accaaggacc tgaacgcaag
     5041 catgcccatg ttttctttca ttttgaagat ggtggcacgc ttgtttatga ggatgttcgc
     5101 aagtttggaa ccatggaact cttggtgcct gaccttttag acgtctactt tatttctaaa
     5161 aaattaggtc ctgaaccaag cgaacaagac tttgatttac aggtctttca atctgccctt
     5221 gccaagtcca aaaagcctat caaatcccat ctcctagacc agaccttggt agctggactt
     5281 ggcaatatct atgtggatga ggttctctgg cgagctcagg ttcatccagc tagaccttcc
     5341 cagactttga cagcagaaga agcgactgcc attcatgacc agaccattgc tgttttgggc
     5401 caggctgttg aaaaaggtgg ctccaccatt cggacttata ccaatgcctt tggggaagat
     5461 ggaagcatgc aggactttca tcaggtctat gataagactg gtcaagaatg tgtacgctgt
     5521 ggtaccatca ttgagaaaat tcaactaggc ggacgtggaa cccacttttg tccaaactgt
     5581 caaaggaggg actgatggga aaaatcatcg gaatcactgg gggaattgcc tctggtaagt
     5641 caactgtgac aaattttcta agacagcaag gctttcaagt agtggatgcc gacgcagtcg
     5701 tccaccaact acagaaacct ggtggtcgtc tgtttgaggc tctagtacag cactttgggc
     5761 aagaaatcat tcttgaaaac ggagaactca atcgccctct cctagctagt ctcatctttt
     5821 caaatcctga tgaacgagaa tggtctaagc aaattcaagg ggagattatc cgtgaggaac
     5881 tggctacttt gagagaacag ttggctcaga cagaagagat tttcttcatg gatattcccc
     5941 tactttttga gcaggactac agcgattggt ttgctgagac ttggttggtc tatgtggacc
     6001 gagatgccca agtggaacgc ttaatgaaaa gggaccagtt gtccaaagat gaagctgagt
     6061 ctcgtctggc agcccagtgg cctttagaaa aaaagaaaga tttggccagc caggttcttg
     6121 ataataatgg caatcagaac cagcttctta atcaagtgca tatccttctt gagggaggta
     6181 ggcaagatga cagagattaa ctggaaggat aatctgcgca ttgcctggtt tggtaatttt
     6241 ctgacaggag ccagtatttc tttggttgta ccttttatgc ccatcttcgt ggaaaatcta
     6301 ggtgtaggga gtcagcaagt cgctttttat gcaggcttag caatttctgt ctctgctatt
     6361 tccgcggcgc tcttttctcc tatttggggt attcttgctg acaaatacgg ccgaaaaccc
     6421 atgatgattc gggcaggtct tgctatgact atcactatgg gaggcttggc ctttgtccca
     6481 aatatctatt ggttaatctt tcttcgttta ctaaacggtg tatttgcagg ttttgttcct
     6541 aatgcaacgg cactgatagc cagtcaggtt ccaaaggaga aatcaggctc tgccttaggt
     6601 actttgtcta caggcgtagt tgcaggtact ctaactggtc cctttattgg tggctttatc
     6661 gcagaattat ttggcattcg tacagttttc ttactggttg gtagttttct atttttagct
     6721 gctattttga ctatttgctt tatcaaggaa gattttcaac cagtagccaa ggaaaaggct
     6781 attccaacaa aggaattatt tacctcggtt aaatatccct atcttttgct caatctcttt
     6841 ttaaccagtt ttgtcatcca attttcagct caatcgattg gccctatttt ggctctttat
     6901 gtacgcgact tagggcagac agagaatctt ctttttgtct ctggtttgat tgtgtccagt
     6961 atgggctttt ccagcatgat gagtgcagga gtcatgggca agctaggtga caaggtgggc
     7021 aatcatcgtc tcttggttgt cgcccagttt tattcagtca tcatctatct cctctgtgcc
     7081 aatgcctcta gcccccttca actaggactc tatcgtttcc tctttggatt gggaaccggt
     7141 gccttgattc ccggggttaa tgccctactc agcaaaatga ctcccaaagc cggcatttcg
     7201 agggtctttg ccttcaatca ggtattcttt tatctgggag gtgttgttgg tcccatggca
     7261 ggttctgcag tagcaggtca atttggctac catgctgtct tttatgcgac aagcctttgt
     7321 gttgccttta gttgtctctt taacctgatt caatttcgaa cattattaaa agtaaaggaa
     7381 atctagtgcg agtaaaaatc aatctcaaat gctcctcttg tggcagtatc aattacctaa
     7441 ccagtaaaaa ttcaaaaacc catccagaca agattgaggt tttaaagtat tgtcccaagg
     7501 aaagaaaagt aaccctacat cttgaatcta agtagatttt atggtaaaat aatagggatt
     7561 ttaaggagtt tgatatgtat aacctattat taaccatttt attagtatta tctgttgtga
     7621 ttgtgattgc aattttcatg caaccaacca aaaaccaatc cagcaatgta tttgatgcca
     7681 gttcaggtga tttgtttgaa cgcagtaaag ctcgcggttt tgaagctgta atgcagcgtt
     7741 tgacagggat tttagtcttt ttctggctag ccattgcctt agcattgacg gtattatcaa
     7801 gtagataaga aaataatggg caggactagg tctttgcctc tttttatttt taaaggatgt
     7861 ttgagaaggt tttacagtaa aagaaaatta aaaaatctag aaagaaaata tgaaagatag
     7921 aataaaagaa tatttacaag acaagggaaa ggtgactgtt aatgatttgg ctcaggcttt
     7981 gggaaaagac agttccaagg attttcgtga gttgattaaa accttgtcct taatggaaag
     8041 aaagcaccaa attcgttttg aagaagatgg tagtctgaca ttagaaatta agaaaaaaca
     8101 tgagattacc ctcaagggga tttttcatgc ccataaaaat ggctttggct ttgttagtct
     8161 ggaaggcgag gaggacgacc tttttgtagg gaaaaatgat gtcaactatg ctattgatgg
     8221 tgataccgtc gaggtagtga ttaagaaagt cgctgaccgc aataagggaa cagcagcaga
     8281 agccaaaatt attgatatcc tagaacacag tttgacaaca gttgtcgggc aaatcgttct
     8341 ggatcaggaa aaacctaagt atgctggcta tattcgttca aaaaatcaga aaatcagtca
     8401 accgatttat gttaagaaac cagccctaaa attagaagga acagaagttc tcaaagtctt
     8461 tatcgataaa tacccaagca agaaacatga tttctttgtc gcgagtgttc tcgatgtagt
     8521 gggacactca acggatgtcg gaattgatgt tcttgaggtc ttggaatcaa tggacattgt
     8581 atccgagttt ccagaagctg ttgttaagga agcagaaagt gtgcctgatg ctccgtctca
     8641 aaaggatatg gaaggtcgtc tggatctaag agatgaaatt acctttacca ttgacggtgc
     8701 ggatgccaag gacttggacg atgcagtgca tatcaaggct ctgaaaaatg gcaatctgga
     8761 gtttggggtt cacatcgcag atgtttctta ttatgtgacc gaggggtctg cccttgacaa
     8821 ggaagccctt aaccgtgcga cttctgttta cgtgacagac cgagtggtgc caatgcttcc
     8881 agaacgacta tcaaatggca tctgctctct caatccccaa gttgaccgcc tgacccagtc
     8941 tgctattatg gagattgata aacatggtcg tgtggtcaac tataccatta cacaaacagt
     9001 tatcaagacc agttttcgta tgacctatag cgatgtcaat gatatcctag ctggcgatga
     9061 agaaaagaga aaagaatatc ataaaattgt atcaagtatc gaactcatgg ccaagcttca
     9121 tgaaacttta gaaaacatgc gtgtgaaacg tggagctctc aattttgata ccaatgaagc
     9181 gaagatttta gtggataaac aaggtaagcc tgttgatatc gttcttcggc agcgtggtat
     9241 tgccgagcgg atgattgagt cttttatgtt gatggctaat gaaacagttg ccgaacattt
     9301 cagcaagttg gatttgcctt ttatctatcg aattcacgag gagcctaagg ctgaaaaggt
     9361 tcagaagttt attgattatg cttcgagttt tggcttgcgc atttatggaa ctgccagtga
     9421 gattagtcag gaggcacttc aagacatcat gcgtgctgtt gagggagaac cttatgcaga
     9481 tgtattgtcc atgatgcttc ttcgctctat gcagcaggct cgttattcgg agcacaatca
     9541 cggccactat ggactagctg ctgactatta tactcacttt accagtccaa ttcgtcgtta
     9601 tccagacctt cttgttcacc gtatgattcg ggattacggc cgttctaagg aaatagcaga
     9661 gcattttgaa caagtgattc cagagattgc gacccagtct tccaaccgtg aacgtcgtgc
     9721 catagaagct gagcgtgaag tcgaagccat gaaaaaggct gagtatatgg aagaatacgt
     9781 gggtgaagag tatgatgcag ttgtatcaag tattgtcaaa ttcggtctct ttgtcgaatt
     9841 gccaaacaca gttgaaggct tgattcacat cactaatctg cctgaatttt atcatttcaa
     9901 tgagcgtgat ttgactcttc gtggagaaaa atcaggtatc actttccgag tgggtcagca
     9961 gatccgtatc cgtgttgaaa gagcggataa aatgactgga gagattgatt tttcattcgt
    10021 acctagtgag tttgatgtga ttgaaaaagg cttgaaacag tctagtcgta gtggcagagg
    10081 gcgtgattca aatcgtcgtt cggataagaa ggaagacaag agaaaatcag gacgctcaaa
    10141 tgataagcgt aagcattcac aaaaagacaa gaagaaaaaa ggaaagaaac ctttttacaa
    10201 ggaagtagct aagaaaggag ccaagcatgg caaagggcga gggaaaggtc gtcgcacaaa
    10261 ataaaaaggc acgccacgac tatacaatcg tagatacgct agaggcaggg atggtcctga
    10321 ctggaactga aatcaagagt gtacgagctg ctcgaattaa tctcaaggat ggctttgctc
    10381 aagtgaaaaa tggagaagtt tggctgagca atgttcatat cgcgccttac gaagagggca
    10441 atatctggaa ccaggaacca gaacgtcgtc gtaaactcct gctccataaa aagcaaattc
    10501 aaaaattgga acaagagatc aaagggacag gaatgacctt agttcccctt aaggtctata
    10561 taaaagatgg ctacgctaag cttcttttag gacttgccaa agggaagcat gactatgaca
    10621 aacgggagtc tatcaaacgt cgtgagcaaa atcgagatat cgcgcgtgtg atgaaagctg
    10681 ttaatcagcg ataaaaagag gaattgaaaa tggaaaaatt agttgcctat aaacgcatgc
    10741 ctttgtggaa taaacaaaca atgcctgaag ctgttcagca aaagcacaat acaaaagttg
    10801 ggacttgggg gaaaattact gtcttgaagg gagctctcaa gtttattgaa ttgacagaag
    10861 aaggggaagt tctagctgaa cacctctttg aagcaggggc agacaatcca atggcccaac
    10921 ctcaagcctg gcaccgagtg gaagctgcca cagatgatgt ggaatggtac ttggaatttt
    10981 attgtaaacc tgaggattat tttgctaaaa aatacaatac caatcctgtt cattcagagg
    11041 tcctagaggc catgcagaca gtgaaacaag ggaaagcttt ggatttgggt tgtggtcagg
    11101 ggcgtaattc tctttttcta gcccagcaag attttgatgt gacggctgta gatcaaaatg
    11161 gactagctct tgaaatcttg caaagcattg tggagcagga agatttggac atgcctgttg
    11221 gcctttacga tatcaattca gctagcattg aacaagaata tgattttatc gtttcaacag
    11281 ttgttctcat gtttctacaa gcggaccgca ttccagctat tattcaaaat atgcaggaga
    11341 aaaccagtgt tggtggttac aaccttatcg tttgtgccat ggacacggag gattatcctt
    11401 gctcggttaa cttcccattc acctttaaag aaggagaact ggcagactat tacaaggatt
    11461 gggaattggt taagtacaat gaaaatccag gccatttgca ccgtcgcgat gagaatggca
    11521 atcgtattca actacgcttt gcgaccttac tagctaagaa aatcaagtaa acacacatga
    11581 agattaggaa ttttcctgat cttttttctt ttttacgaat gatatagaaa aggagggaat
    11641 tcatgtttgt tgcgagagat gctaggggag aattggtaaa tgtgttagag gataaacttg
    11701 agaagcaagc atacacctgc ccagcttgtg gaggccagct ccatttgcgt caaggaccaa
    11761 gtgtacggac gcattttgcc cataaatcct taaaagactg tgattttttc tttgaaaatg
    11821 aaagtccaga acacctggcc aataaggaat ccctctatca ctggttgaaa aaagagacaa
    11881 aggttcaatt agagtacccg ctttcagaac ttaaacagat tgcggatgta tttgtaaatg
    11941 gcaatctagc tctagaagtt cagtgtagtc ccttgcctca gaaagtcctt aaagagcgaa
    12001 gtgagggcta tcgtagtcag ggttaccaag tactgtggtt gctgggtcaa aaactgtggc
    12061 tcaaggagcg tttgactcgt ctacagcaag gttttcttta tttcagtcaa aacatgggct
    12121 tttatgtttg ggaattagac aaggaaaaac aagttttaag actcaaatac ctgatttacc
    12181 aggatctccg cggtaaactc cattatcaaa tcaaggaatt ttcctatggt caaggtagtt
    12241 tattggaaat attgcgtctt ccctataaga gacaaaaaat atctcatttt acagtttctg
    12301 aggacaagga catctgtcgc tatatccggc aacaacttta ttatcaaaat ctcttttgga
    12361 tgaaagaaca agcagaagcc tatcaaaagg gagaaaatat cctgacttat ggactgaaag
    12421 aatggtatcc acaaattcga ccaatagtgg gcaaattttt ccagattgaa caagacttga
    12481 ctagctatta tcagcacttt tatacctatt accaaaaaaa tcctcaaaat gattggcaaa
    12541 agctttatcc accagccttt tatcagcaat atttcttgaa aaatatggta gaatagaaag
    12601 gatggaggaa tctaatggta ttacaaagaa atgaaataaa tgaaaaagat acatgggaac
    12661 tatcaacgat ctacccaact gaccaggctt gggaagaagc cttaaaagat ttaacagaac
    12721 aattggagac agtagcccag tatgaaggcc atctcttgga tagtgcggat aacctactag
    12781 aaatcactga attttctctt gaaatggaac gccagatgga gaagctttac gtttatgctc
    12841 atatgaagaa tgaccaggat acacgtgaag ctaagtatca agagtactat gccaaggcca
    12901 tgacactcta cagccagtta gaccaagcct tttcattcta tgatcctgaa tttatggaga
    12961 ttagcgaaaa gcagtatgct gactttttag aagctcaacc aaagctgcag gtttatcaac
    13021 actattttga caagctcttg caaggcaagg atcacgttct ttcacaacgt gaagaagaat
    13081 tattggctgg agctggagaa atctttggtt cagcaagtga aaccttcgct atcttggaca
    13141 atgcggatat tgtgttccct tatgtcctag acgatgatgg taaagaagtt cagctatctc
    13201 atgggactta cacacgtttg atggagtcta aaaaacgtga ggttcgccgt ggtgcctatc
    13261 aagctcttta tgcgacttac gaacaattcc aacacaccta tgccaaaacc ttgcaaacca
    13321 atgttaaggt gcaaaattac cgtgctaaag ttcgtaacta caagagtgct cgtcatgcag
    13381 ccctcgcagc gaattttgtt ccagaaagtg tttatgacaa tttggtagca gcagttcgca
    13441 agcatttgcc actcttacat cgctatcttg agcttcgttc aaaaatcttg gggatttcag
    13501 atctcaagat gtacgatgtc tacacaccgc tttcatttgt tgaatacaat tttacctacc
    13561 aagaagcctt gaaaaaagca gaagatgctt tggcagtctt gggtgaggat tacttgagcc
    13621 gtgttaaacg tgccttcagc gagcgttgga ttgatgttta cgaaaatcaa ggcaagcgtt
    13681 caggtgccta ctctggtggt tcttacgata ccaatgcctt tatgcttctc aactggcagg
    13741 acaatctgga caatctcttt actcttgttc atgaaacagg tcacagtatg cattcaagct
    13801 atactcgtga aactcagcct tatgtttacg gagattactc tatctttttg gctgagattg
    13861 cctcaactac caatgaaaat atcttgacgg agaaattatt ggaagaagtg gaagacgacg
    13921 caacacgctt tgctattctc aataacttcc tagatggttt ccgtggaaca gttttccgcc
    13981 aaactcaatt tgctgagttt gaacacgcca ttcaccaagc agatcaaaat ggggaggtct
    14041 tgacaagcga tttcctaaat aaactctacg cagacttgaa ccaagagtat tatggtttga
    14101 gtaaggaaga caatcctgaa atccaatacg agtgggctcg cattccacac ttctactata
    14161 actactatgt atatcaatat tcaactggct ttgcggccgc ctcagccttg gctgaaaaaa
    14221 ttgtccatgg tagtcaagaa gaccgtgacc gctatatcga ctacctcaag gcaggtaagt
    14281 cggactatcc acttaatgtc atgagaaaag ctggtgttga tatggagaag gaagactacc
    14341 tcaacgatgc ctttgcagtc tttgaacgcc gtttaaatga gtttgaagcc cttgttgaaa
    14401 aattaggatt ggcataaaat ggttgaatcg tatagtaaga atgctaacca taacatgcgt
    14461 cgtcctgtcg tcaaagaaga aattgtagac ttgatgcgtc agcgtcaaaa gcaggtcaca
    14521 ggttccttga aagaattgga agactttgcc cgcaaggaaa atattcctat tattccccat
    14581 gaaacggttg cttatttccg ttttcttatg gaaaccatgc agcctaaaaa tattctggaa
    14641 attgggacgg ctatcggttt ttcagctctc ttgatggctg aacatgcgcc aaatgctaag
    14701 attacaacta ttgatcgtaa tccagaaatg attggttttg ccaaggaaaa ttttgcccag
    14761 tttgacagtc gcaagcaaat cactctccta gagggagatg cggtggatgt cttatctaca
    14821 ctgacagagt cttatgattt cgtctttatg gattctgcca agtctaaata catcgtcttt
    14881 ctgccagaaa tcctcaaaca tttggaagtt ggtggtgtgg ttgtcttgga tgatattttt
    14941 caaggtggtg atgttgccaa ggatattatg gaagtccgtc gtggtcagcg aaccatttat
    15001 cgaggccttc aaaaattatt tgatgtaacc ttagacaatc cagaactcac cgcaacatta
    15061 gtgcctttag gagatggtat tctcatgctt cgtaaaaatg tagcagatgt tcaactgtct
    15121 gaaagcgaat gattttcaga aaaatttaag aaaaaatagt aaaatagata gggtaacact
    15181 tatctcaaag gagtagacat gaagaaaaaa ctattggcag gtgccatcac actattatca
    15241 gtagcaactt tagcagcttg ttcgaaagga tcagaagggg cagaccttat cagcatgaaa
    15301 ggggatgtca tcacagaaca tcaattttat gagcaagtga aaagcaaccc ttcagcccaa
    15361 caagtcttgt taaatatgac catccaaaaa gtttttgaaa aacaatatgg ctcagagctt
    15421 gatgataaag aggttgatga tactattgcc gaagaaaaaa aacaatatgg cgaaaactac
    15481 caacgtgtct tgtcacaagc aggtatgact cttgaaacac gtaaagctca aattcgtaca
    15541 agtaaattag ttgagttggc agttaagaag gtagcagaag ctgaattgac agatgaagcc
    15601 tataagaaag cctttgatga gtacactcca gatgtaacgg ctcaaatcat ccgtcttaat
    15661 aatgaagata aggccaaaga agttctcgaa aaagccaagg cagaaggtgc tgattttgct
    15721 caattagcca aagataattc aactgatgaa aaaacaaaag aaaatggtgg agaaattacc
    15781 tttgattctg cttcaacaga agtacctgag caagtcaaaa aagccgcttt cgctttagat
    15841 gtggatggtg tttctgatgt gattacagca actggcacac aagcctacag tagccaatat
    15901 tacattgtaa aactcactaa gaaaacagaa aaatcatcta atattgatga ctacaaagaa
    15961 aaattaaaaa ctgttatctt gactcaaaaa caaaatgatt caacatttgt tcaaagcatt
    16021 atcggaaaag aattgcaagc agccaatatc aaggttaagg accaagcctt ccaaaatatc
    16081 tttacccaat atatcggtgg tggagattca agctcaagca gtagtacatc aaacgaatag
    16141 tccaaatcaa tgagtcaggg aaaaaactcg acttcaggaa aaaatgaagc aaacattccc
    16201 acaataaaac gcatagtaca aggtttgtac tgaccccaaa agttagacaa ttaatttatc
    16261 tgaaggattt agttctgtat tgcacagggc taagtccttt tagttttacc ttaattctct
    16321 tattgttgta ataatcaata tagtctataa tggcttgttc caattgatta agtgatttaa
    16381 atgttttctc atagccataa aacatttcgg attttaaaat gccaaagaaa gattccatcc
    16441 taccgttgtc ttggctgttt cctttgcgtg acatagatgc ttgaattccc ttactctcta
    16501 ggaagcgatg ataagaatcg tgttggtatt gccagccttg gtcactatgg agaatcgtat
    16561 tctcgtagtg cttctctttg aatgcctgtt ccaacattaa cgatcaatca atttaatcat
    16621 atacctaa
//
LOCUS       DAVMAH010000050        14160 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVMAH010000050 DAVMAH010000000
VERSION     DAVMAH010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14160
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.050"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(248..1855)
                     /locus_tag="VYO94_001621"
     CDS             complement(248..1855)
                     /locus_tag="VYO94_001621"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV1760229.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2245..2832)
                     /locus_tag="VYO94_001622"
     CDS             complement(2245..2832)
                     /locus_tag="VYO94_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV1760230.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(2960..3409)
                     /locus_tag="VYO94_001623"
     CDS             complement(2960..3409)
                     /locus_tag="VYO94_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760231.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3414..3803)
                     /locus_tag="VYO94_001624"
     CDS             complement(3414..3803)
                     /locus_tag="VYO94_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV1760232.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3831..4457)
                     /locus_tag="VYO94_001625"
     CDS             complement(3831..4457)
                     /locus_tag="VYO94_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1760233.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4471..5034)
                     /locus_tag="VYO94_001626"
     CDS             complement(4471..5034)
                     /locus_tag="VYO94_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1760234.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5199..5433)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5487..5990)
                     /locus_tag="VYO94_001627"
     CDS             complement(5487..5990)
                     /locus_tag="VYO94_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV1760235.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6183..7013)
                     /locus_tag="VYO94_001628"
     CDS             complement(6183..7013)
                     /locus_tag="VYO94_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1760236.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(6998..8680)
                     /locus_tag="VYO94_001629"
     CDS             complement(6998..8680)
                     /locus_tag="VYO94_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760237.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETPELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(8782..8994)
                     /locus_tag="VYO94_001630"
     CDS             complement(8782..8994)
                     /locus_tag="VYO94_001630"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760238.1"
                     /translation="MKIKEQTRKQVAGCSKQCFEVVDETDEVSNHTYGKAKLTWFEEI
                     FEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(9001..9549)
                     /locus_tag="VYO94_001631"
     CDS             complement(9001..9549)
                     /locus_tag="VYO94_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV1760239.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINS
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9564..10412)
                     /locus_tag="VYO94_001632"
     CDS             complement(9564..10412)
                     /locus_tag="VYO94_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV1760240.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10601..11950
                     /gene="trkA"
                     /locus_tag="VYO94_001633"
     CDS             10601..11950
                     /gene="trkA"
                     /locus_tag="VYO94_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV1760241.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11954..13393
                     /locus_tag="VYO94_001634"
     CDS             11954..13393
                     /locus_tag="VYO94_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1760242.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLITLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKMVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(13518..13775)
                     /locus_tag="VYO94_001635"
     CDS             complement(13518..13775)
                     /locus_tag="VYO94_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEV1760243.1"
                     /translation="MNEGAQLAEVRVIANSGAYGAHYDIMGVYDLIILAPQVRSYYRE
                     MKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
BASE COUNT         4162 a         3220 c         2602 g         4176 t
ORIGIN      
        1 tttcaattca ctatacaatc cagttcctaa aactttgcta gaaattgatt tggctttccg
       61 aattaatttg ttcaaatttt atttcatttc aatatactga taaatccatt cactagcaca
      121 gggcaagagg gagtcgctat tgatttcaac ggtagcaggt acatacagag gacccctacc
      181 tcagatatac tgcaatatca tcgtatgcaa aaaacctctg agatttttct caaaggttct
      241 gattttgcta attgctgttc tcaactgctg cagtaacaaa ggcagtgtag agttcttctg
      301 gtcggtttgg acggcttgac agttcagggt gatactgaca agctacaaag aatttatttt
      361 caggaatttc cacgatttct accaaacgat tgtctggaga aactcctgaa aagacaaaac
      421 ctgctgcctc aaactgctca cggaaggcat tattaaactc ataacggtga cggtgacggc
      481 gttgcaccac ttcttgattg tgataagcag cagcagcctt agagccacgt ttcaacttag
      541 acggataaag tcccaaacga agggttccac ccatatcctc aatatcaatc tgatcacgca
      601 tgatatcaat gatagggtat tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa
      661 gacctaaaac gtgacgagca aactcgatac atgtcaactg cattcccaag cagactccca
      721 acattggaac atcattttca cgcgcatagc ggatggcttg gattttccct tctgtaccac
      781 gttgaccaaa accacctggt acgatgatcc cgtccgcatc agacaagagt tctgctacat
      841 tctctgctgt cacatcattg gcattgaccc aattgatttt aacttctgca tcattgacat
      901 agccagagtg tttcaaggct tcgaccactg agatataggc atcttgcaac tccacatact
      961 taccaacaag ggaaatctta acttgtttct tgaggttcat gaccttgtcc accatggctg
     1021 accattctgt catatccgct gctggtgcgt ctaatttcaa atgatcacaa acaatttggt
     1081 ccatcccttg tgcctgcaag ttcagtggaa tttggtaaag gtgttcaaca tccaacgatt
     1141 cgataacggc ttctggtgcc acatcacaga actgggccag tttattttta attccttgac
     1201 cagctggctc ttctgtacga ataaccaaca tatttggttg gattcccaag ccacgcaatt
     1261 ctttgacaga gtgttgggtt ggtttggttt tcatttcacc agcagccttg aggtaaggaa
     1321 gcaaggttgt atggatatac atgacattat ccgcacccac atctgccttc atctgacgaa
     1381 gagcctctag gaatggcaag gactcgatat ctcctactgt tccaccaacc tctgtgataa
     1441 tgacatcaga gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa gcatctgtga
     1501 tatgaggaat gacttgaaca gttgccccaa ggtattctcc acggcgttct ttacgaagaa
     1561 cttcactgta aattttccca gttgtcacgt tggaatattt gttgagattg atatcgatga
     1621 aacgttcata gtgacccaag tccaaatctg tctcagctcc gtcatctgtc acaaaaactt
     1681 ccccgtgctg gtaaggactc atggttcccg gatcaatatt gatataaggg tcaaactttt
     1741 gaatggttac tttgagacca cgatttttca agagacggcc tagactcgct gccacaatcc
     1801 ctttcccaat ggacgatacc acaccaccag ttacaaaaat atatttcgta gacatagatt
     1861 cctctttcta aaatgctcaa ggtcttgtta actacgaggg gatatagaaa acaagaccct
     1921 actaataaga ataatctggg acgactgcac cagattcaca actaatactc ttcgaaaatc
     1981 tcttcaaacc gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt tgtcagtctt
     2041 atctacaacc tcaaaacagt gttttgagca gcctacggct agtttcctag cttgctcttt
     2101 gattttcatt gagtataaaa tacaagaaga taacttcttg aaaaaacaaa aatagctccc
     2161 taagaactag ggagccccga cctctaaaag aggtgcccaa acaatatgat acctaaaaat
     2221 aggataattg tcaatagcta actcttattc ctcgctggtt tcagcatcgt catctgaaaa
     2281 ctcgtcgtcg tcttcgttga gatccacatc ttctcccaag tcatctggag cgatttcgtt
     2341 gatttctgca tcataagctt ccacttcatt tttttcatca tctggatttt catcatcgta
     2401 tgaaagagct ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc
     2461 aatggcatct gaatcaccat ccataaaggc attgacacgt tttttcttag cttttggtgc
     2521 tacttcatcg tcgtcatttt cttcaagagc gatgatttct tcgtcgattt cgtccacacc
     2581 ataccatgaa cgaagacccc atttgttgtc cccaagtgag atgaagctac cgtcaaagtt
     2641 caactctgtg tagaacaaag gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta
     2701 gttttgaatt tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac cacgaagttc
     2761 caagatagca cgcgctacct caatcataga tagttcactt ttttcttgcc cagcaaatac
     2821 ttctaattcc aaagcgtttc tcctcattta tactactatc gccagagcga acagactctg
     2881 acctcatttt atcatttact ctttatttta cgataatttt gcggaatagt caaaggttaa
     2941 gggggagaaa gtggcaggat tagactaatt ccaatataaa actccttcct ttttctgttg
     3001 ctccattttc cacaaatcca agcgacttga aacacctcct agaagcatga ttgtaggtgt
     3061 agatttcctt gactctcaat tctttccatc cttttactcg agccaattca atcaaagcac
     3121 ttagaatctt ttttccaagt cctcgatgtt ggtaagcgga attcccaatc acaatgggga
     3181 gattatcctg agatagtgta atatccccaa ttggaaacca ttctcccttc tccttgactt
     3241 caatccaaaa aagctcacca tgccgatcca aataggaata catggcttcc aaggtcgctt
     3301 gactgtaagg aagcttcacc ccatctacga ggtaaaccaa gttcacatcc tgataccaag
     3361 caaaagcttc ctcacaataa ttgaccttat aataaggaac aaaacacaat gcactacctt
     3421 ttcaacaaaa gagttgctgc ttgattaaaa ccatcacacc agttatacca ttttgcttca
     3481 tacccatctt gagctaggat acgatcttct aaatcaaaaa cagagtaaat ctttctttcc
     3541 tcgcaagctt gcgcatagag atgatatagt tcatcaccac catctctatc ccactcagca
     3601 gaaatcgtat cccgacctgc caataaagcc tgataagccc tgtgatgccc atctgtaatc
     3661 agcaaacaat ctccaaaggc aagaatactg attggatcga cttggattgt ttctgccgac
     3721 tggtaaagca tctgaatatc ttgcaacttc ttttctgata aatatagttg agtcggatga
     3781 agatctgcta tattgacttt catttctttc tcctcaaggg aattcgatac tcacttctgt
     3841 ttgcctttaa atcgccattg gaagcggagc ttgtcataga agggaaactc gataaacagg
     3901 actcccaagc ccacacagag actggcaagg acgtctgatg ggtaatgaac tcccagatag
     3961 actcttgata ccagcacact gactaggtag aggccaagga cgatttgtac gatttttctc
     4021 cagactggat ctttaatccg ctgactaaga ataacaatca aagtacctac catcaaggtt
     4081 acagccagag aatgcccact tgggaaggaa aatcccttct cctccaccag atgtaagata
     4141 tctggccgtg ggcgctggta gatattttta aaggtcacga ttaaaagacc tgccaaagcc
     4201 agatttccca gcatgaagaa actttctatc ttccatcgct tacgataaaa gacaaaagct
     4261 gtaatgacaa cccaagtgat aatcactggg atatcaatca gacgtgtgag ggatcgaaaa
     4321 agaatagtca aataatctgg taagtctcct cgaatggcag tctgaatcga ttggtcaaaa
     4381 ttgaccaaca tttcagggta aaatttgacc atatagccaa gaataacgaa aagtaaaagg
     4441 gcaaaactgc ccttcattaa aaatgtttgt ttatctttca tagtgtttta aggttggttt
     4501 caaaaggacg tacaacaacc agaatgaaac ggaaaagatt acaccctcaa tcaagttaaa
     4561 aggtaatacc atggtcatta ggtagttgga aagtcccaaa atttttccaa tatcaaagtt
     4621 agcaaactta gcgtacaaag gaacagcata aacatagttg agaaccaaca tggccaaggt
     4681 taaaccaaca gttccagcta gagagcctag taggaaacga agggttgtcc gttccttttt
     4741 ccaaatcaaa gcaaatacga tgacaaaaac tcccaaagct acgatattca tcggcaaacc
     4801 aatgtaagta ttcactcctt ggctgttaag aagcaatttc aatagtgagc gaagcaagag
     4861 cactcctaga gcagcaggca aatccatgac caccagaccc acaaggactg gcaagatact
     4921 aaattcgatc ttgaggaaag atgccgctgg taaaagcgga aagtcaaagt acatcagcac
     4981 aaatgagatg gctgataaaa ttgcaatggt cgaaagtcga cgtgtgtttg tcataacagg
     5041 ttcctccaat tttctataaa atcagaagaa gttggaaagg attcctctat ctattctcac
     5101 tttttatatc ccaaaagttc cctcttactc tattaaagaa aaacaaagca agtggttaca
     5161 atccggctat aaatctatca aaacagacaa agctattctt tcgtcttctc ccatccagac
     5221 tatactgtcg gttgtggaat ctcaccacat cagcttgcgc tcgcggactt ctttaaagag
     5281 aaggaaatag agatttttct tttagactag gcgacaagct gtaggcataa cttctggtta
     5341 ggcaaagctt gtcaacaaag tataaaagga aaagatcatt tcctagttaa agtcaccgcc
     5401 ggtcgggaat cacaccctgc cctgaagact cttttatcat aacaaaaaac gcttgcaagc
     5461 gcaagcattt tgttcatttt cattttttat ttcaatttat ccacttcata ggtatggacg
     5521 agctcaagac ctgcaaagtt ctgctggcga agagcctcat agacaatcat gcagacggta
     5581 ttagacacat tgagactgcg gacatgttca tcattcatgg gaatacggag agccttctca
     5641 ggatgttctc gcataaaatc ttcaggtaag cccttgtctt cacgtccaaa gagaaaataa
     5701 tggtcctcgt cagtcgataa atccacctca gaatagactt tttccgcgaa tttcgaaatc
     5761 agatagagtt ttcccttcat ctgagatatg aaatcttcca aactctcgta aaaataaatc
     5821 tctagcttat cccagtaatc caatccagcc cgcttcatct tgcggtcatc aataggaaag
     5881 cccataggct tgatgatgtg gaggggagaa ttggtcgcag cgcaagtacg cgcgatattg
     5941 cccgtatttt gtggaatttg aggttcaaat aatacaatgt gatttgtcat gacttgcttc
     6001 ctttcaccat tgcaaaaaaa tagccacact gcccggagtc aagctcagca aacagcgtgg
     6061 ttaaggcatc gttaacttac ctcacaacag gtttgaagta aatcagcgaa actactttct
     6121 tagtataaca ctttcagaat cattgtcaat agaaatgact tgattttttc aattttttca
     6181 agctatttcc aagggttata aaatcgtccc tgattctgca agataagtag taaactaact
     6241 actaaaaaca aggttgccaa gagcaaggta atatagtctc cttttttcaa ggcctgataa
     6301 ctataccatg tgcgtttttt ctctttccca aagcggcgaa gctccatggc agtcgcaatg
     6361 gtatcaatgc gttctagcga gctaaaaatc aagggcgtaa taatgagcag attgcctttg
     6421 attcgttgca taagagaagc tttcttggat aattccatcc cacgcgcctc ctgagacatc
     6481 ttgatagtaa agaattcttc ctgcaaatct ggaatatagc gcaaggtcag gctgacagaa
     6541 taagcaatct tatagggcac accaatttga tttaaactgg aagcaaactg actaggatgg
     6601 gttgtcatca aaaagataat agccagagga atggtgcaaa gatacttaat ggccaaattt
     6661 agcagataaa agagctcctg gctggttaga gtgtagacac cgattccctg ccaaatcaca
     6721 cttctctctc cataaagtcc aaccccatac tcgggagaaa agagatagac catcaaaacg
     6781 tttaaaacgg caaataccgt cgcaaaaacg gctacaaagg aaacatcttt aaagcgaatt
     6841 tctgataaat agaggagaaa gactgaaaag atggcaatca gcaagagcat tctggtatca
     6901 tagctaatca tggccgccaa tgataccaga atgaaaaaga gaagtttccc agctcctgac
     6961 aagcgatgaa tcacagtatc tctatgctgg taaccgatta atttagcttg catccctctc
     7021 tcctttcttt gtaaaatgcc gttaaatcca gtggatccac atctagtttc ttagccaagt
     7081 taaagatgga ggtttctttt agattggctt ttactaacag ctcaggatcg ctcaacagac
     7141 tggctggaac agtatcggca atcaattctc catccaccat gacaaggacc cggtctgaat
     7201 aatccagcat caattgcata tcatgggtaa tcatgacaat ggtatgccct ttttgatgta
     7261 actcttcgag aaattccata atctcagtat agttcttctg atcttgacct gcagtcggtt
     7321 catctaggag aataatttca gctcctaaga ccaaaattga agcaatggtg acacgttttt
     7381 tctgaccaaa tgacagggca gaaataggcc aattacggaa ttcataaagt ccacagattt
     7441 tcaaggtttc atagactctc gtttcaattt ccttctcatc cacacctcgc aaacggagcc
     7501 ctagagccac ctcatcaaaa atcatattgg ttgaaatcat ttgattagga ttttgtagca
     7561 catagcctac tcgttccgcc cgctctgcaa cagaatcgcc ttttatatcc tgtttttccc
     7621 aaagatagcg tccttccgtc tgaataaagc tacttatagc cttggctaga gttgatttcc
     7681 ctgctccatt ttttccgaca atagcaatct tttcaccctt tttaatatct aaatgtaggg
     7741 attttaaaat cggtctatca tcataagaaa aagatacttc ctctagtcta aagagtgact
     7801 gcaattctgg ggtttctttt accagttccg tctgtaactg gacttgccct tttgagatag
     7861 acaagttatc cagatctgct aattgttctt ccttgactaa gtccacacct aattgacgga
     7921 gagtcgttag ataaaggggt tctcgaattc cattttgagt caataaatca gtcgcaagca
     7981 actggtcagg gctcccatta aaaaggatac gaccatcgtt tatcaagaca atccgatcca
     8041 cagggcgatg cagaacgtcc tccaaacggt gctcgataat cagagtcgtc gtcccctctt
     8101 ccttatgaat ctggtcaatc aattcgataa tatcctgacc tgacttggga tctagattgg
     8161 cgagtggctc atcaaacaag agaatcggac tttcatcaat caagacacca gccagactga
     8221 ctcgctgctt ttgtccacct gacaaatcct gaggacgctg atccagtaaa ggaagaaggt
     8281 ccagcttttc agcccattta taaacacgac ctttcatctc atctagggct gtcacatcat
     8341 tttccagagc aaacgccaaa tcttctgcca cagacaagcc aataaactgc ccatctgtat
     8401 cctgcaaaac tgtgctaacc agatgagact tatcatagat gctcatatca aaggctgttt
     8461 gaccctttat caaaaattct ccatatgtct gacccttgta aatattggga ataatcccat
     8521 tcaaacactg acccaaggta gatttacctg acccagatgg tccaacaatt aagactttct
     8581 ctcccttgta aatggtcaag tctatccctt gcaaggtcgg ttcttgttgt gtttcatacc
     8641 ggaaagagaa atccttccac tcaattatag cttctttcat cttactctct tcattcgctt
     8701 cttagacttc tattttatca taaatcaagc ccttcttgca gtctcttctc ttaaaatctt
     8761 agcgccaaaa agattcctat cctagcttac ttgcctaact aatctataaa catcgaaaaa
     8821 gactagttgc ccagccttcc ccatcatttt atactcttcg aaaatctctt caaaccacgt
     8881 cagcttcgcc ttgccgtagg tatggttact gacttcgtca gtttcatcta caacctcaaa
     8941 acactgtttt gagcaacctg cgacttgctt cctagtttgc tctttgattt tcattgagta
     9001 ttagtccttt ttcaaacttc ctgcacgagt ttgggttcct gcataggcaa gtaagagaag
     9061 agttcctgca atagctacag atacaccatt ggcaattccc gcaacaatcc cttgtgcaaa
     9121 tactttttct gccgcttctt gataaatcac aacatctcca agtggtgcca agacacccca
     9181 aacaagggca tttgcaagta gttgaatgag attaaaaata agaatatctt tccagtcaaa
     9241 aacactattg atcacgcgaa cgtactttct aaaaagtccc acaactaaac caaagagtcc
     9301 gctagcgata atccaagtcc accatagacc ataaccaaca agagagtcct tgattgcatg
     9361 accaatcaac ccgacaagca aaccgataat cggtccaaaa ataatagaaa gtagcgcttg
     9421 taccgcatac tgaagctgta tgcttgtatt tggaacaggg gttggaatgt tgatcatccc
     9481 gatgacgaca aagagggcag cgccaattcc gacagcaaca acttgtttaa ttgtaaattt
     9541 gatttccata ctattctcct attttatcct tctattttct ttatttcaat ggtccaagat
     9601 gaaccgacac ctacattata ggccttggca aaggaacctt ggttgatagc caaacctaaa
     9661 cgatagagag agttgatgta aaggatgggt tgcccaattc tcacatctgc aaatgatttg
     9721 ccatagacaa cctgattttg atagaccagc atatcagcat gatagatggt cacttcaaaa
     9781 cgatcaccaa attctggttc caacttgtaa aattcttccc gtgtgataga ggtccaaagc
     9841 gaaccgaaac gcacatccag aatatcaatg gctcccttca ccagatggtc ttctatgatg
     9901 gtcgctacga ctggaagctc tacaatctgt tccacactga gctctggccc tacttcctca
     9961 aaagtaatgt gaccactggc cagtttagca ccagtatagg catagacatc acgaccgtgg
    10021 aaggtataag aatgctctgt gttttgacgc ctattggcca cctcagaaat ctcacgaatg
    10081 gctacaatgc caacgtgttt cttgataaag gaaagcgtcc cattatctgg cgtgacaatg
    10141 tattgatttt ttgcagtctt ggcaactaca ctcttacgtt tcgaaccgac acctggatcg
    10201 acaaccgata caaacgtcgt tccctcaggc cagtaatcca ccgtctgaaa gagacgatag
    10261 ctcccctcaa aaatattata aggcgtgata tcgtgcgtca agtgatggat ttttaaggtt
    10321 ggagactctt ctaaagccac tccaatcata gccgataccg caccatcaac cagaccaaag
    10381 tctgattgta ataccagtaa attattattc attttatctc cttgtatatc ctttatcata
    10441 ccatatttca gagaaagtcg ctaatagcta tttcaattgg ttagggtata gttttaactt
    10501 atagcaaatt tcctactaaa aactctggtt attagctagt aggtgcattt tttcttgaaa
    10561 aagggtatga tagttacatc atgaaaaagt aggttttatt atgaaaatta tccttgtcgg
    10621 agggggaaaa gttggttttg ccctctgtcg ctccttggtt gcagaaaagc atgatgtttt
    10681 gctgattgag caagacgaag ctgttctcaa tcatattgtc agtcgctttg atatcattgg
    10741 tatccttggt aacggggccg attttgccat tcttgagcaa gccagcgtcc aagattgtga
    10801 tatctttatc gccctgactg agcacgatga agtcaacatg attgcagcag ttctagccaa
    10861 gaaaatggga gctaaagaaa ctatcgttcg ggtgcggaac cctgaatatt ctaactctta
    10921 tttcaaggaa aagaatattc tcggtttttc tcttatcgtt aatcctgagc tcttggctgc
    10981 ccgcgctatc gcgaatatca ttgacttccc caacgccctg tctgtcgaac gctttgctgg
    11041 tggacgcgtt agcctcatgg aatttgtcgt caagtccacc agcggtcttt gccaaatgcc
    11101 catttctgat tttcgtaaaa aatttggtaa tgtcattgtc tgtgcgatag agagggatca
    11161 tcaaattatc attccaagcg gtgacatgac tgtacaggat aaagatagaa tctttgtcac
    11221 tggtaaccgt gtcgatatga tactcttcca taattatttt aaatcacgcg ccgtgaagag
    11281 ccttctcatc gttggggcag gtagaattgc ctattatcta cttggtattc tcaaagatag
    11341 tcgtatcgat acaaaagtca ttgaaatcaa tcctgaaatc gccagcttct ttagcgagaa
    11401 attcccaaat ctctacatcg ttcaaggaga tggaaccgca aaagatatcc tgctggaaga
    11461 aagtgctcaa cactatgatg ccgttgcgac tctaacagga gtcgatgagg aaaatctgat
    11521 tacatctatg ttccttgaca gggtaggtgt acagaaaaat attactaagg tcaatcgtac
    11581 cagtctcctc gagattatca atgcgcctga tttttcaagt atcatcacac ctaaaagcat
    11641 cgctgtagat acgattatgc actttattcg tggtcgagtt aatgcccagt attcagacct
    11701 tcaagccatg caccatctag ccaatggcca aattgaaacc ctgcaattcc atatcaagga
    11761 agccaataaa atgactgcca aacctctttc tcaactgaaa ttgaaaaaag gggttcttat
    11821 tgcagccatt attcgaaagg gcaagactat tttcccaact ggggaggata tgttggaagt
    11881 tggagacaag ctcctagtaa caaccttgtt gccaaacatc accaagattt atgacttgat
    11941 tgcgaggtaa gaaatgaata aaagtatgat tcgttacctc ctttcaaagt tacttttgat
    12001 tgaagctgtt ctcctcttgg ttcctgtggc tatcgctgtc tattaccgtg aatcgagcca
    12061 agtctttaca gccctctttt cgaccatagg gattctcgta ttgttaggcg gttcagggag
    12121 tttacagaag ccaaaaaatc aacggattta tgccaaggag ggagtcttga tcgttgccct
    12181 ctgttggatc ctttggtctt tctttggtgg tctccccttt gtcttttctg ggcaaatccc
    12241 tagccttatt gatgcctttt ttgaaattag ttctgggttt acaactactg gagcaagtat
    12301 tttgaacgac atttcggttc tcagccgttc cctcctcttc tggcgaagtt ttacccactt
    12361 gattggaggg atgggagtgc ttgtttttgc acttgctatt atggacaatg ccaaaaatag
    12421 tcacctagaa gtaatgaagg ctgaggttcc tggtcctgtc tttggtaagg ttgtatccaa
    12481 attaaaaaac actgcccaga tcctctatct cctttacata gccctctttt ccctctttgt
    12541 catcatctat tatctagccg gtatgcctct ctacgatagt tttgtcattg ctatggggac
    12601 agcgggaact ggaggattta ccgtctataa cgatggaatt gcccactatg gtagctcact
    12661 gattacctat ctggttagta taggagtttt ggtttttggg gtaaatttca atctctacta
    12721 ctaccttatg ctccgtcggg ttaaggcctt ctttggagat gaagagcttc gggcttactt
    12781 ggtcatcgtg ctggtttcta caggcttgat taccctcaat actctctacc tctacccagg
    12841 gttttcaaag agctttgaaa tgaccttctt ccaggtttcc aacatcatta caacaactgg
    12901 ttttggatat ggagatatta ccaactggcc cctcttctcc cagtttatcc tccttttcct
    12961 catggcaatc ggtggctctg ctggatcaac tgcaggtgga ctcaagatta ttcgaggcct
    13021 catcctttca aaaattgcca aaaaccaaat tttgtcaatc ctatcgcccc accgtgtttt
    13081 gaccctccat gttaataaaa tggtgattga caaagatacc cagcataaga ttctcaagta
    13141 ctttgtcatc tatgctatga ttttgctagc gcttatcttt attgtcagcc tagatagcaa
    13201 tgattttctg gtcgtgacca gcgctgtctt tagctgtttc aataatatcg ggcctattct
    13261 aggaaccact tctagtttct caatctttag tcccatctca aaaattctcc tctcctttgc
    13321 aatgattgca gggcgcttgg agatttaccc tatcctcctt ctctttatga aaagaacttg
    13381 gtctaagaga taaaatacaa aatccctctt tttacaattg tgaaagaggg atttttatat
    13441 taaaaagggg gaacgttttt aaatccaagc ctgtctgtaa gcaaagttct tactcaaata
    13501 aaagatggaa aaacttacta cacagcttgg taatgctcca atacaaattg taaggcttta
    13561 cttggattct ttgttaaatg aatatattcc attcctctgg tagcaactat ctgaatacct
    13621 aatctttctg catccacctt catctctcta taataactcc gaacttgtgg agccagaata
    13681 attaaatcat aaacacccat aatatcataa tgagctccgt acgctcctga attcgcaatc
    13741 actctaactt ctgctaattg agcgccctcg ttaattgcat tggctaatta cgcacttgtt
    13801 ccagaccctg cacaaagaac cagtactttc aactccttac tttttattac atctatctca
    13861 ccaggcatta tttcacttgt atcctcctct aaaataatat catttgagct tgcaatatct
    13921 acaacctgta gtagatatct cgtatttaga caatatgaaa acaagacgac ttccatatag
    13981 gaaaccgcct tctctctatg ttgagtgatt tatattaaaa taacttttct tctagctgca
    14041 ttttattatt ataaaaacat tcatcataac cctgaactta aataacgatt tttattcaag
    14101 atacatactc ctagaataaa ctttatatga aattctcatt tttgttttta caattctccg
//
LOCUS       DAVMAH010000051        13590 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVMAH010000051 DAVMAH010000000
VERSION     DAVMAH010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13590
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.051"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(209..1177)
                     /locus_tag="VYO94_001636"
     CDS             complement(209..1177)
                     /locus_tag="VYO94_001636"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1760244.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1322..2105)
                     /locus_tag="VYO94_001637"
                     /pseudo
     CDS             complement(1322..2105)
                     /locus_tag="VYO94_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
     gene            complement(2130..2627)
                     /locus_tag="VYO94_001638"
     CDS             complement(2130..2627)
                     /locus_tag="VYO94_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV1760245.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2700..4061)
                     /gene="radA"
                     /locus_tag="VYO94_001639"
     CDS             complement(2700..4061)
                     /gene="radA"
                     /locus_tag="VYO94_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV1760246.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4075..4590)
                     /locus_tag="VYO94_001640"
     CDS             complement(4075..4590)
                     /locus_tag="VYO94_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1760247.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGEMLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4592..5035)
                     /locus_tag="VYO94_001641"
     CDS             complement(4592..5035)
                     /locus_tag="VYO94_001641"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV1760248.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAAGGVRTGGFGSTGH"
     gene            complement(5320..5685)
                     /gene="lytA"
                     /locus_tag="VYO94_001642"
                     /pseudo
     CDS             complement(5320..5685)
                     /gene="lytA"
                     /locus_tag="VYO94_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
     gene            5705..5872
                     /locus_tag="VYO94_001643"
     CDS             5705..5872
                     /locus_tag="VYO94_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HEV1760249.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            complement(6027..6230)
                     /locus_tag="VYO94_001644"
     CDS             complement(6027..6230)
                     /locus_tag="VYO94_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760250.1"
                     /translation="MRPKRYPYSGQKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYEAIHDTSQVTQ"
     gene            complement(6253..6444)
                     /locus_tag="VYO94_001645"
     CDS             complement(6253..6444)
                     /locus_tag="VYO94_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1760251.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            6509..6748
                     /locus_tag="VYO94_001646"
     CDS             6509..6748
                     /locus_tag="VYO94_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760252.1"
                     /translation="MTFKEYLLKASKRDIYDDGKDFDFETIFAREILRYAHDSELETK
                     TGFFRHLEIMNADSWFVELARSIYQDFEKSISDSH"
     gene            7161..7529
                     /locus_tag="VYO94_001647"
     CDS             7161..7529
                     /locus_tag="VYO94_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1760253.1"
                     /translation="MFETFEKIKELAKKRGKALGQVEEDLGYGRNTLYKIKNSTPNAE
                     RIAEIANYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            7529..7762
                     /locus_tag="VYO94_001648"
     CDS             7529..7762
                     /locus_tag="VYO94_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760254.1"
                     /translation="MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLTREDIA"
     gene            7762..8025
                     /locus_tag="VYO94_001649"
     CDS             7762..8025
                     /locus_tag="VYO94_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1760255.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            8038..8418
                     /locus_tag="VYO94_001650"
     CDS             8038..8418
                     /locus_tag="VYO94_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV1760256.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHNSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTRSEHQNARLRCENEADRNMIHHLVKDALENLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLALVN"
     gene            8435..9499
                     /locus_tag="VYO94_001651"
     CDS             8435..9499
                     /locus_tag="VYO94_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HEV1760257.1"
                     /translation="MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGY
                     DIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYF
                     VTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFD
                     IDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIV
                     KGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEEIVEVTDEIITTPAELEVYTV
                     VKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFPVS
                     TPLEVANYANEILEVIKKFS"
     gene            9554..10696
                     /locus_tag="VYO94_001652"
     CDS             9554..10696
                     /locus_tag="VYO94_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1760258.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKIKQKLGEKQHSVSNITFEKLYEEFEENWKHGVKNSTVYASKNVKKEILKQIE
                     GDYLVRNIDRRLLQKVIDQLLQDGRSHNYVSKIKFKLNQIMKFAIRMNYIDTNEMLFV
                     ETPRKVITSDELRKKNTKYLDQKEFKLFIQNLKDEALCDYRITKYIRIAKVLFLTGMR
                     YGELAALNYKEDIDFSKKTIHIKHTYDFRQKERTTPKTIKSDRVITAPQKVLDIIKEQ
                     IIENATNGFDTDFIFINTLGEPITNARVICALKRHGQKIGIEKNITTHTFRHSHISLL
                     AELGIPLTAIMDRVGHSDSKTTLEIYSHVTQKMVSDISSKLDKIKF"
     gene            complement(10779..10872)
                     /gene="ffs"
                     /locus_tag="VYO94_001653"
     ncRNA           complement(10779..10872)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VYO94_001653"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(10905..11372)
                     /locus_tag="VYO94_001654"
     CDS             complement(10905..11372)
                     /locus_tag="VYO94_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV1760259.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(11573..12859)
                     /locus_tag="VYO94_001655"
     CDS             complement(11573..12859)
                     /locus_tag="VYO94_001655"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV1760260.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(13090..13326)
                     /locus_tag="VYO94_001656"
     CDS             complement(13090..13326)
                     /locus_tag="VYO94_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV1760261.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
BASE COUNT         4514 a         3047 c         2212 g         3817 t
ORIGIN      
        1 cctactagaa ttctccttag aaagcgtcga ttcaagtgct atcactgttc aaaaatgatg
       61 gtcgctgaaa cttctgatga cgtatagtca tatttcttct ctttttatta tatcacagtt
      121 ttaaatctag ctttactaga ttcaccgcta ctatccattt attcggaaaa aagacgaaaa
      181 aacctgagaa tcatctcagg cttggtcatt aaattttttt ctcaatatcg aaaagtggag
      241 aaagtggtcg tttttcatga atacgtacga tagcatcccc taggagatga gcgattgaaa
      301 tctgctcaat cttatcaatc aaacgctctt ctggcagata gatggtatcc aaaacaacca
      361 atttcttaat agctgatttt tggatattgt ccgtagcagg accagaaaga actgggtgcg
      421 tacagcttgc atagacttca acagcaccag cttccgcaag agcatctgcc gcatgacaaa
      481 tcgttccagc ggtatcaatc atatcatcaa tcaagataca agtcttgcct tcaaccttac
      541 cgatgatgtt cataacttca ctagtattca tcttatcaac gctacgacgt ttatcaataa
      601 tagcgataga tgttttcaaa aattctgcca acttacgagc acgagtcacc cctccatggt
      661 ccgggctgac aaccacatag tcagaaccaa ccataccacg ccgctcaaaa taatctgcaa
      721 ttagaggagc acccatcaaa tgatccacag gaatatcaaa gaatccttga atttgcgcag
      781 catgcaagtc gatggtcaat aaacgatcca ctccagctac ttcaagcata tttgcgacaa
      841 gttttgaagt gattggctca cgcgctctcg cctttctatc ctgacgtgca tacccatagt
      901 aaggcatgac aacattgaca gactctgcac tcgcacgctt caaagcatct accataatca
      961 aaatttcaag cagattgtca tttacaggcg aactagttga ttgtaagata aagacgtgtt
     1021 tcccacggat tgattcttca atgttgacct gaatctctcc atctgaaaat tggcgaacac
     1081 ttgatttccc caactctatc ccaatctcct gcgccacacg ttctgccaat tctttattag
     1141 aagaaagggc aaacagcttt aaatcagaaa aagacatgat ttcctccggt atatatgtat
     1201 cgcttgtgct tttcacaaga ttttccatct accattgtag cgctttttgc actatttttc
     1261 aatcaaaaat aaaagaaggg caccatattt gtacccttgc atcattcttt tgaaaaatat
     1321 tctaggtcat caactcattg tgtttctcaa caaagcaata agcatgataa taaccataga
     1381 gagcaatagc cgtaaccact ggaatcgcta aaggcaactc tgtttccaac tccacaaaag
     1441 gagagttaaa caataagacc ctgtttcttg ccaaccttct gtcctttata ggctctgtaa
     1501 agcaagtaaa cacctactac agctagacct gaaaaagtcc agtgagaggc aattcctgag
     1561 atgatacgct ctaaaattcg cgaaatagta aagtcaaagc cctctggcaa atccgtacga
     1621 atataaccaa tatcctcaat catttggaat cccaaaccgg aagcaattcc aagtaaaaac
     1681 aaaaatttta attttcgcac aggaatcaaa gccaaaacaa aaacaagtgg caataatttc
     1741 aagggttctt ctaccaaagg agccacaata gcactttcaa aggcatttaa aaatggacta
     1801 tctgggaaaa gaacccccag taaatcatgg atataagtat tagcaaaact agacaaccag
     1861 cctaaaagga acatccctcc caataaagac agaatcaaaa ccttctttgg caattcccat
     1921 tttttcccaa tacggaagag aaaataaaga gccggaatca tgtaaaagag agctagaaag
     1981 atagaaactc ccattagtcc atattccgca cctgacctcg aaccgtccgt atagtagatg
     2041 gtttcatact gtaaaccaat acatagcaat aaaataaaaa taaataaaat actgcttttc
     2101 ttcatacact ttctttctaa atgaagtatt tataattcta cgactgtcat acttcctgta
     2161 tcaacattgt aaatagcacc agagataatg acatcgtctg gtattagggg agactcgata
     2221 agcagttgca tatcctcgcg tacactctct tctatatctt ggaagggcaa gaagtcctgg
     2281 tctgacacat ctacacctaa ttcctctttt aaatactcct gaaaaggttc attttcaaag
     2341 gtctgagcac cacagtctgt atgatgcaat accacaattt ctcttgtccc catttgttgc
     2401 tgggaaataa ctagagaacg aatcatatcc tcagtcactc gaccacctgc attccgcaaa
     2461 atatgagcat ccccaagtgc caaacctaga gcttgcgcaa cgtgcaaacg tgagtccata
     2521 caggtcacaa tggctactct ggttttaggt ttaagtggca gatttaactg cccatgtagg
     2581 gcaacataag cctgattggc ttgcataaac tgttcaaaat acgacacgat tccctccttg
     2641 aaaatttgat agtcaaatat ttctcctatc ttatcatttt taagagaatt tgtcacggat
     2701 tatgcaaaga cctttttcaa gacttcctga atcgtggtca cgccaatgac ctgaatttcc
     2761 ttaggcagag tgattcctgt caaggaattc ttaggtacat aaatcttagt aaagcccagt
     2821 ttagcagctt cgttgatgcg ttgctcaata cgattcacgc gccgaatctc tcctgtcaag
     2881 cccagttctc cgacaaaaca ttcctgagga ttagttggct tgtctttgta gctcgaagca
     2941 atagcaactg caacagccaa gtcaatcgca ggttcatcca atttaacacc accagcagat
     3001 ttgagatagg catcctgatt ttgcaagaga agccctgccc gtttttccaa aacagccata
     3061 atcaagctag cacggttaaa atcaagtcct gtcgtagtac gcttggcatt tccaaacatg
     3121 gtcggtgtta ccaaagcctg aacctccgcc aaaatcggac gcgtcccttc catggttaca
     3181 acgatggagg aaccagtcgc cccatccaaa cgctcttcta ggaaaacttg actcggattg
     3241 agtacctcaa ccaagccgcc cgactgcatc tcaaaaatcc caatctcatt agtggaacca
     3301 aaacgatttt tgaccgctct caaaatacga aaggtgtggt gacgctcccc ttcaaagtaa
     3361 agcaccgtat ccaccatatg ctccaacata cgaggcccag ccaaggttcc ttctttggtc
     3421 acatgaccta cgataaagat ggcaatgtta ttggtcttgg ccaactgcat gagttcagcg
     3481 gtcacttcac gcacctgaga aacagacccc tgcacccctg aaatctcagg agacatgatg
     3541 gtctggatgg aatcaataat gagaaagtct ggctggatac gctccacttc tgcacgaaca
     3601 ctctgcatat tggtctctgc atagagataa aactcactat caatatcacc taagcgctct
     3661 gcacgtagtt taatctgctg ggcagactcc tccccactga catagagaac tgtccccact
     3721 tgggacaact gggttgagac ttgtaggaga agagttgatt tcccaatccc aggatcccca
     3781 ccgatgagga cgagacttcc tggtaccact ccgcctccaa gcacacggtt gaattcctcc
     3841 atctccgtct tagttcgatt gacattgatg gaagtcacct cagctagttt catgggcttg
     3901 gttttctcac ctgtcaagga cacacgcgca ttcttgacct cggcaacctc aacctcttcc
     3961 acaaaagaag accaagaccc acagttgggg caacgtccca gatatttagg ggaattatac
     4021 ccacaatttt gacatacaaa tgtcgctttt ttctttgcga tgacaaacct ctttctatat
     4081 ctctaactca cactcaatca cttggcaaaa atcaatcttc tcatttggca caaactggcg
     4141 catgagcatt cgatgagcaa caactaccac agtctgatgt tctcgatact tagacataca
     4201 ttctagaaac cgagacttca tttccgtagc tgtctcatat tgaataggac tattaggaag
     4261 catctccccc ttgttttcta aaaacagtct tctagctgtt tcaaagtttt ctattcctgt
     4321 tttatagacc tgccattcat gtaataaagg ctctactctt aaaggaagac ccgtagcaca
     4381 gaccacatac gaagccgttt ctaaagctct tgtgactgca gaagatacga ttatttcagc
     4441 tgacgagagt aaaggatttt tgctcaattt ctggacttgc tgccgtccca tctcagacaa
     4501 gggtgccaaa tctatcccaa atcctatata agaacgctcc tctaactcac ggtaatctgg
     4561 ctccccatga cgtacaaaga taatcttcat tctagtgccc tgtcgatcca aatccaccag
     4621 ttcgaacgcc accagctgca tctccatctg caattaagaa agtagcaaaa acagcctgga
     4681 caatacgttc cccaacttca agaacaacct cttggtctgt gatattcttc atctgcgcaa
     4741 aaatatgccc ttcatttcca ggatttccat aataatcccc atcaatgacc ccaactgagt
     4801 taattaaaac caagcccttc ttacgaggat ttgaagaacg atcatagagg tagagaacct
     4861 cagtcggctg catataagcc ttaacccctg tcggaaccaa gacaatctct cctggcgcaa
     4921 caactgtacg cacagcaacc tttaagtcgt aaccagccgc atgcgctgtc tcacgcttgg
     4981 gcaataaatt ttcatctgta aaactcgaaa ccaattcaaa accacgaatt ttcataattt
     5041 tctcttttct attatcattt attctagatt attctatctt atttattcgg aaaaagcacg
     5101 aaaaaaagag cacacaacaa ttataggcga tacgataatt tacactgttt cacaatacgt
     5161 tgaaatttag agctttaaag cgagggcaaa gttgattttt tacatcgttt tacagaggtt
     5221 tacgacactt ttgccccttt tttgcccctt ttgagcaaac aaaaaaaccg caagcctgag
     5281 cctgcggtga aagaacaatt tagaaagttt cctttctatt tatttaactg taatcaagcc
     5341 atctggctct actgtgaact ctggcttatc tgccagtgtt ccgtctggtt tgaggtagta
     5401 ccagcctgtt ccgtccgctg actggataaa agcatttgat accatagcac cttctttagc
     5461 gtctaagtag taccaagtgt ccttgtactt gacccaacct gtttgcatag caccttctac
     5521 atcaaaatag taccacttgt cagcgatttt cttccagcct gtggccattt cgcctgattg
     5581 gtcaaagtaa taccaattac cgtctgtgtg cttcttccag cggtctgcaa gcatatagcc
     5641 tgagccatcg aaataatacc aggtaccgtt gattttctca aacttataga aaggaggaga
     5701 tagtatggca aatactccaa taaaacctgg aacagataat cagaaacctg gtcgctatgt
     5761 agaggtagga cctcgtggcg gaaaagttac taatggtcat accgcaacta tcggaaaagg
     5821 tgatcggctc cctccgacat ctgctaaagg caacggttgg aaaaaagtct aatcttcgtt
     5881 tgcgtacaat cgttcaatgg ttgtacgctt tttccataca caaaagcaca ttcccaaaaa
     5941 atcaatttga atccatgctt cggcgtaatc tttcccattg ctggcatagt gagttatata
     6001 atggtgaatc attttattcc ttcctcctat tgagttactt gagaagtatc atgaatggct
     6061 tcatagctaa gacgcttaaa ttcttctgag tctatctgaa aattgatagg ctttttttgt
     6121 aaacactcaa gaaaactagt gtttcttaaa agtttttcaa ctaactcagg gtctgccttt
     6181 acaaaggtgg actctttttg tccactatac ggatatcgtt ttggtctcat tttcctactc
     6241 ctcaaatctt tcctactcaa tcccataatc ttcaataacc tgaagaatga aactgttcgc
     6301 tcgtggacct ttagtcgttc cacttagaat gtttgtcact tcctgtcgtt taaagccgta
     6361 agcaaccgct agagttgctt ttttaatgcc tttctctttc aagaaagcaa taactctttc
     6421 gcgaccgttt gcgatatctg gcatattttc tcctttcttt ttctttcttc tttttctgct
     6481 ataatataag cagaaaggag ttaaccttat gacttttaaa gaatatttac tcaaagcaag
     6541 caaacgcgac atctacgatg atggtaaaga ttttgatttt gaaaccatct ttgctagaga
     6601 aatattacgt tatgcacacg attctgaact ggaaaccaaa acaggtttct ttcgtcatct
     6661 tgaaatcatg aatgctgatt cgtggtttgt tgaacttgct cgctcaattt atcaagattt
     6721 tgagaaatca atttcagatt ctcactaatc gagcgtgact tttttgatat ggcaatctca
     6781 aaaatttacc accagcgctg actaccttaa tgactttttc aaggtggtct ttttcttgtt
     6841 ctaaattttt aagaatactt accatcagca cgttcctcct ctttacttat ttgtaaataa
     6901 gaaacaacta aaaatgtaac tatttttctg cattatactt gacaacttac accaaatcgg
     6961 ctaaaattaa agcataataa aaacaccaat aaatctataa ataccgttcg ccaaaacatt
     7021 tttataattt atttcttagt tgttttttta gttgtttatc acttacaaaa aacattttac
     7081 accttttggg ataattagtc aaccttttta caccaaattt gttaaatttt ttgtgatgtc
     7141 ttagaaaggt tgatttaaca atgtttgaga catttgaaaa aataaaagaa ttggcaaaaa
     7201 agcgtggaaa agctcttgga caagtagaag aagacttagg ttatggtaga aatacactct
     7261 ataagataaa aaattctacg ccaaacgctg aacgtatcgc agaaattgct aattatttca
     7321 acgtatccac cgactacctg ctcggacgaa cagataaccc tgctatcgct gggagtgatg
     7381 aatttgccca agtaaacgga caaatcatag acttacgcaa agcagcagcc aacaccatgt
     7441 tatttgacgg gaaaccacta aatgaagatg atatcgactt cattacatcc gtcctatccg
     7501 cccacttcaa aagcaaagga gaacgctaat gactatcact atcaacttca cagaaaaaaa
     7561 ttcctacatt acggactacc taaacaaaca cggtatcgac acaacgacca tggattttga
     7621 cgacttcatg gcactcatgg aagatatcga agacgcacga gcagccgacc aagcctatat
     7681 ggagtattta gccgacccag ctacttatac catggatgag gtcttggatg aactaggact
     7741 aactcgagag gatattgctt aatgtatcgg ctagatattg ataaaaaagc tctcaagcaa
     7801 cttaaaaaac tagatacccc aaccagaaaa caaatcctat cctggcttgc taaaaacatt
     7861 gaaaacacga ccaatccacg acaacacgga aaagcactaa aagccaacct tgcaggttac
     7921 tggcgataca gagtagagaa ttaccgcatc atctgtgata tccaagacga taaactagtc
     7981 gtcctagccg tggaaatcgc ccaccgcaga gatgtctata aataacgaag gagaactatg
     8041 acactcgcta aactctgcga agaatatcaa gtagaacttt gtctcttcga cggttcaaac
     8101 tggcacaata gcggtttcta caatccagac acaaacgtgc tcgctattga ccacaacttg
     8161 actcctgaac aacaaatcca agtcgcccta cacgaacttg gacacaaaga ccacacacgc
     8221 tcagagcacc agaacgcccg tctacgctgt gaaaacgaag ctgataggaa tatgatccat
     8281 catctcgtaa aagacgctct agaaaactta gacgacccca cagagtttga ttacctcaaa
     8341 ttcatgtctt actacaatct aaaaaccatg acaaatgaaa tcatggttaa agaagagtat
     8401 ttagcattag taaattaaaa aaaggagtat caatatggaa attgataaag taaaagccga
     8461 tttaaaacaa gtcggcaaac gtgtagcaga cctcagccaa agcattacga atgaagaaca
     8521 aacaaagaat gccttcatta tgccgttctt ccaagcgctt ggatatgata tcttcaatcc
     8581 acttgaattt gtcccggaat ttactgccga cgtgggcatt aaaaaaggcg aaaaagtcga
     8641 ctatgcgatc attttggatg gcgagcctca aatcctaatt gaatgtaaat caattacaga
     8701 aaaccttact aagcacgact ctcaactatt cagatatttc gtaactacta aatcaaaatt
     8761 cggtatcttg acaaatggta gagaatataa attctttact gatttagatg agccaaataa
     8821 aatggacaca actccattct taacaatcga tgtgactgat atcaaagaaa atcaatttac
     8881 tgaaatcatc aaattccaca aagagaattt tgatattgat aatattgttt catcagcttc
     8941 tgaattgaaa tacctcaaca atcttaaagc gttccttact gaaaatatca ctacaccgtc
     9001 agatagcttc ctcagatatc taacttctga aatctatgaa gggcgtgtta ctcaaaatat
     9061 cttaacgaca ttttctccca ttattgtgaa agggtttaat caattcatca cagagcgagt
     9121 taatgaaaaa ttaagtgctg cacttaatac aagcgttgaa accaaagtaa caaccgatat
     9181 tccaaaagtt gaagctgaag agattgtcga agtaactgac gaaattatca caactcctgc
     9241 tgaattagaa gtttatactg ttgttaaaat gcttgctagg gatgtagttt ctccagaacg
     9301 tgtattttac agagataacc gtagctattt caatgttttg gttgacgata acatcaaaaa
     9361 atgggtatta cgttatcgtt caaattcaaa aaaaagcact atcgaaatcc gtgataaagg
     9421 catcttcccg gtgtctaccc ctctcgaagt cgcaaattat gccaatgaaa ttttagaagt
     9481 aatcaagaaa ttctcataat aaaaaaagcc ctctttacta tacccatttt atcaaaaaag
     9541 tgaggtaaaa tcaatgtgga tggaagaatt gccaaacggc aaatataaat tttttgagag
     9601 atacaaagat ccatatactg agaaattaaa aaaagtctca gtaacgatgg agaaaaaaac
     9661 tccccaagca agaaatcaag ctgcgatttt acttcaggaa aagataaaac aaaagttagg
     9721 agaaaaacaa cattctgttt ctaatataac ttttgaaaaa ctatatgaag aatttgagga
     9781 gaattggaaa cacggcgtaa aaaactcaac cgtctacgct tcaaagaatg taaaaaaaga
     9841 gattttaaag cagatagagg gcgactacct agttagaaat attgatagac gtttattaca
     9901 aaaagtaata gatcaactat tacaagatgg gagatctcat aactatgttt ctaaaatcaa
     9961 attcaagctc aatcagataa tgaaatttgc tatcagaatg aattatattg atacaaatga
    10021 aatgctattt gttgaaacgc ctagaaaagt aattacatcc gacgaactca gaaagaaaaa
    10081 tacaaaatac ttagaccaaa aagagtttaa gttattcatc caaaatttaa aagacgaggc
    10141 cctatgtgat tatcgaatta caaagtatat ccgaatagct aaagttcttt ttcttactgg
    10201 aatgaggtat ggagagctgg cagccttaaa ctacaaggaa gatatagatt tttctaaaaa
    10261 gactattcac atcaagcata catacgattt cagacaaaaa gagagaacta caccaaagac
    10321 aatcaagtcc gatagggtta taacagcacc tcaaaaagtg ttagatatta tcaaagagca
    10381 aataatagag aatgcgacaa atggatttga tacagatttt attttcatca atactctagg
    10441 agaaccaata acaaatgcca gggttatttg tgcattgaaa agacatggtc aaaaaatcgg
    10501 catagaaaaa aacataacta cacatacatt tagacattct cacatatccc tacttgctga
    10561 gctgggcatt cccttgactg ccatcatgga cagagtaggg catagtgact caaagaccac
    10621 actagagatt tattctcacg ttactcaaaa aatggtatca gacatatcta gcaagttaga
    10681 caagataaaa ttttaaattg tgcccctcgt ctgccccttt ttcttataca agacaaacaa
    10741 aaacccctta aagtgttgat tttaaagggt ttttaaagtg cacgaaaaaa gagcacacaa
    10801 ttcaaatcgc ttagggctgc tggattcctc ccctgacccg cttcacgcag aactgttgct
    10861 ccactattta ttatatcaca ttcctattca ttttaaaagc aaaattattt tttccgtcta
    10921 tttctaaaaa aatcctgcat gatagctgcg cattcatctt ccaaaattcc tatttcaacc
    10981 tccacacgat gattgagacg ctcatctgtc aagatatcgt acaaactccc agcagcgcca
    11041 aatttctggt ttttagcccc atagaccaca tttggaatgc gggcaagccc aatcgcccca
    11101 ctacacatga cacaaggttc aatggtcaca aaaagtgtgc aatccagcaa gcgccagctc
    11161 tcctcactca agttcgcatc ctctatagcc ataatttccg catgcataac cgctcgctgt
    11221 aattcctcac gcgcattatg cccacgacca atgatttccc catctttgac aatcacacaa
    11281 ccaattggaa tttcatcgtg ttcaagagca atctcagcct ctctcaaagc ctccctcata
    11341 aagacttctt tttcttcaag cgtataatac atctcttttc tcttttccta cttatcgatt
    11401 ttattattat atcatgaatc ccaacacaaa agaagccacc gaatgcggtg actctatagg
    11461 gagattatta tgaaaaagaa aagtttagga tatttgttac aacaagttag gaggtcttct
    11521 tgtaaccgtc tatagtatac ccgacctatc ttaaacaaat cttaaaaatc tcttaggacc
    11581 aaacactttc taaaatattt gtttgttcac gaccaggacc tactgagaaa gtagaaatac
    11641 gaacgccaac caattcactc acacgacgaa catagttacg cgcattctca ggaagatctt
    11701 ccaaattgcg aactccggta atatcttctg accaacctgg caactcttca tagataggct
    11761 tgcaacgttt caattgctca agactagctg gatagtagtc aatacgttga ccgtcaagat
    11821 cataggccac acagattttc acagtatcca aaccgctcaa aacatcaata gagttcaaag
    11881 aaaggttagt aataccagaa acacgacggc tatgacgcat cacaactgag tcaaaccaac
    11941 ctacacgacg tggacgacca gttgttgtac catattcatg acccacttca cggatacgtt
    12001 ctcccacttc atcaaacaac tcagttggga aaggaccatc tcctacacga ctcgtataag
    12061 ctttacatac acctacaacc ttgtcaatct tgcttggacc gacaccagaa ccaattgtca
    12121 caccaccagc tacagggttt gatgacgtaa caaatggata agtaccttgg tcgatatcta
    12181 gcataacacc ttgtgcacct tcaaaaagca cacgtttgcc attatcaagc gcatcattca
    12241 agataacaga tgtatctatc acgtatttct tgatttgttg accatattcg taatattctt
    12301 caaaaatatc atcgaaaaca atcgctttac tgtcatacaa tttttcaaaa agacgattct
    12361 tttcagcaag gttacgttct aaacgctcac ggaaaatatc tttatctaaa agatctgcaa
    12421 tacgaattcc aacacgagca gccttgtcca tataagctgg accaattccc ttaattgtcg
    12481 taccaatctt attgtcgccc ttagcttctt cttgcaagcg atccaactcg atatgataag
    12541 gcaaaataac atgcgcacga tcagaaatac gcaagttatc agttgttaca ccttcctcat
    12601 gaagatagct caactctttt acaagagatt taggatttac aaccatacca ttcccaatga
    12661 cagatatttt ttcagggaag aaaatcccag atggaatcaa gtgcaactta aatttcttac
    12721 cgtcaatcac aatcgtgtga ccagcattat caccaccttg gtaacgtgca atcacttctg
    12781 cattcgctga aaggaagtct gtaatcttcc ctttaccttc atcaccccat tgggtaccta
    12841 caacaacaac tgaagtcata attttgtctg agccctcagg ctcttccttt ctcacataca
    12901 tggcaggact ctcacctgca attatatctt acaatttatt ataataaaaa atcgcctttt
    12961 tatcaagaag aaacaataga aagatttgct atttccaact attaaaaaat gatttagaaa
    13021 aattactagc tatttactat tatctttcca taaaagagta aattagttcg gaaatttact
    13081 aaaattacct caacaagaaa taaaaccccg attcattacc aatttttcaa gatacaaacg
    13141 ataagcaaca cgataatggt aaacgataaa atccttacga caaccaatgc catatctcac
    13201 taaataataa attaaaaatt taaaatgaac atgttcccag tcaaaattat caccaaatgt
    13261 aggaccatac tcttcttcaa tactatcata gaaattagcc atctgctcat aaattttttg
    13321 taacataatc aaatactcct tttctttttt ataaacttat tctaacaaaa aattttacac
    13381 attcactatc aattcctgaa ttgttaaaat accagcctca acaagataaa aataggaaaa
    13441 gttgacaaaa tagaaacaaa tttgctacct aaatttcaaa caattaaagt tctaaaaaga
    13501 ccgccttaaa acttttgggt aaatcctatt aaaactataa tatttttata taggtattat
    13561 ggttctgatt ttctagtata aaaaaattca
//
LOCUS       DAVMAH010000052        12854 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVMAH010000052 DAVMAH010000000
VERSION     DAVMAH010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12854
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.052"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(34..231)
                     /locus_tag="VYO94_001657"
     CDS             complement(34..231)
                     /locus_tag="VYO94_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1760262.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(306..1082)
                     /locus_tag="VYO94_001658"
     CDS             complement(306..1082)
                     /locus_tag="VYO94_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV1760263.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            1204..1950
                     /locus_tag="VYO94_001659"
     CDS             1204..1950
                     /locus_tag="VYO94_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1760264.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            1963..2943
                     /locus_tag="VYO94_001660"
     CDS             1963..2943
                     /locus_tag="VYO94_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV1760265.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            3138..3458
                     /locus_tag="VYO94_001661"
     CDS             3138..3458
                     /locus_tag="VYO94_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1760266.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            3504..3812
                     /locus_tag="VYO94_001662"
     CDS             3504..3812
                     /locus_tag="VYO94_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1760267.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            3829..5127
                     /locus_tag="VYO94_001663"
     CDS             3829..5127
                     /locus_tag="VYO94_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1760268.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            5278..7716
                     /locus_tag="VYO94_001664"
     CDS             5278..7716
                     /locus_tag="VYO94_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV1760269.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            7735..8403
                     /locus_tag="VYO94_001665"
     CDS             7735..8403
                     /locus_tag="VYO94_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV1760270.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            8421..9509
                     /locus_tag="VYO94_001666"
     CDS             8421..9509
                     /locus_tag="VYO94_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV1760271.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            9964..12465
                     /locus_tag="VYO94_001667"
     CDS             9964..12465
                     /locus_tag="VYO94_001667"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV1760272.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEETAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
BASE COUNT         4178 a         1966 c         2644 g         4066 t
ORIGIN      
        1 tagagtaaaa ttctctacaa aaagaagaat agcctatttg actattcttc cgagtgattt
       61 caatttcttt ggggaaatat ggagatactt tttaaatact ttggcaaaat atttatagtc
      121 tgaaaatcca acttggtcag agatagcgct taaaggggag ttgggagatt cagccatctt
      181 atctatagct tgtttcaggc gatattgtaa gatatattca tttagagtca tggggaagtc
      241 ttctttgata accttatata gatgcttgtt atctgcaaat agctagagca tttcaaggaa
      301 ataaactaga aataacaatt aatatggtgg ttcagaaata ccttttgata atcaataaga
      361 tcttcaggat gaagtgcgtt gattccatcc atttcatatt tccgatttaa taaacgatat
      421 ttgttttcac caaattgatg aaaagggagt agttgaactt ggtcgatatt taatgagtta
      481 aatagagtag cgaatttttc tgcatcctct aaactattgt taaaattagg aataactggg
      541 attcttaaaa cgatagtttt attttgagaa aaagcataat gaatgttttt aataatcatt
      601 tgattaaaaa ccccagtcac ttttttatgt tttatagaat tataatgttt taggtctgtg
      661 tagataaaat ccacatattg aattaaatca ataaattttt catgatcaac aaaggcagta
      721 gtttcaatgg cagtgtgtat gtgatgttct ttagctgatt ttaagatggc tttagcaaat
      781 tcaaactgag caaatatttc acctcctgat aaagttaaac ctccaccgga ttcttcgtaa
      841 aattctttgt cttttaatac ctctgtaata atttcttcta cagtcttttc ttcaccgact
      901 aaggtgaatt tctctcgttg agcatctttc attttttcag gtttcattct ttgagattca
      961 ggattagaac accatggaca gcgcagagga catcctttta aaaaaacagt tgtacgaata
     1021 cccgggccgt catgaattga aaagtgttga atattaaaaa taattccttt agatatttcc
     1081 ataagagttc ctcctcttca taagtctatc ctatcacaaa aacgaaagaa aaacaattac
     1141 gaacgaaagt ttaatttgtt gttttttgct ttttattttg gtagaataaa acggaggtgt
     1201 aaaatgaaaa gattggaaca aattattaaa ttagtatcag aatatgaaaa gatcgacgtt
     1261 aatacattat cggaaaaatt aaatgtatcg aaagtaacga ttagaaaaga tttagataaa
     1321 ttagagtcaa aaggtttatt acacagagag catggatatg ctgtattaaa tagtggagat
     1381 gacttaaatg tacgtttgtc aattaactat gaaattaaga gaaaaattgt tcaggaagca
     1441 gtaaaattgg tgtcagataa tgaaacaata atgatagaat ctggatcgac ctgtgcttta
     1501 cttgctgagg aaatttgcaa gcaaaaaaga aatgttacga ttgtaacaaa ttcatttttt
     1561 atagcaaatt ttgtgagagc ttatgattca tgtcgtatta ttgttcttgg tggagagttt
     1621 cagaaggatt cacaggttac tgtgggacct ttattaaaag aaatgataca gacttttcat
     1681 gtgcatcaag cttttgttgg gacagatggt tacgataaag agatgggctt tacaggaaaa
     1741 gatttaatgc gcagtgaggt agttcaatat atttcagcag cgtcggataa agtcattgta
     1801 ctaactgact caagtaaatt tgataaaagg ggtacagtaa gaagatttgc tttaagtcaa
     1861 gtctatgaag taataacaga cgaaaaactt tctaaacaaa atatagctac attagaaaat
     1921 gctgggataa tggttaaggt agtttcgtaa gaggttaaat gtatgaatca agataggaat
     1981 aaactgctct ctaaaattgc ttatctgtat tatattgaaa acttaaatca gtcacaaata
     2041 gcagcaaaat taggaattta tagaacctct attagtagaa tgttaacaga agcaaggaat
     2101 gcaggaattg ttaaaattga aatagagaat tttgatacca atatgtttaa gttggaaaat
     2161 tatgtaaaag aaaaatatgg tctggaaagt ttagaaatta ttccaaatga atttgatgat
     2221 aatccaacaa ttttatctga aagaatttct caagttgcag caggtgtcct taggaatcta
     2281 attgatgata atatgaaaat tggcttttct tgggggaaaa gtttaagtaa tttagtagat
     2341 ttaattcaca gtaaaagtgt ccgaaatgtt cacttctatc ctctagcagg tggtcctagt
     2401 cacatacacg ctaaatacca tgtgaataca ctgatttatg aaatgtctag aaaatttcat
     2461 ggagagtgta catttatgaa tgcaacgatt gtgcaagaaa ataaattgtt agcagatggt
     2521 attttgcaat caagatattt tgaaaatttg aaaaatagtt ggaaagattt agatatagct
     2581 gtagtcggaa ttggtgattt tagcaataaa ggaaagcatc aatggttaga catgcttaca
     2641 gaggatgact ttaaagaatt gaccaaagtt aaaactgtag gagaaatttg ttgtcgattt
     2701 tttgattcaa aaggtaaaga agtctatgaa aacttacagg aaagaacgat agcaatctct
     2761 ttggaagatt taaaaaatat tcctcaaagt ttagctgttg cttacggtga tacgaaagta
     2821 tcttcgattc tttctgtctt gcgtgctaat ttagtaaatc atttgattac agacaaaaat
     2881 acaattttaa aagttttgga agaagatggg gatttgactt ttagagagat tctaggtgag
     2941 tgaaaatgat agactgattc agtttatcgt ttttcttttt agttgattgc acatttgtgc
     3001 ttatataaac aaaaatagtt tatctgttgt ttttggattg acaactttat tatgtagttg
     3061 tattctatag ttacaaaaga aaattttaaa atttcaaatg aaaaaagctt tttacatagt
     3121 gaaatgagga ggaatttatg gaaattattg ttccagatca aattatcatg ggtttaattt
     3181 tatatgctgg cgatgcgaaa caacatattt ataaagcatt agattacata aagaacggta
     3241 catgtgaacg atgtgaagaa gaaatccagt tagctgatgc agccttatta gaagctcata
     3301 atctacaaac aaaattcttg gcacaggaag cgtctggtac aaagacagaa attacagctc
     3361 tctttgttca ttcacaagat catctcatga ctagtatgac ggagattaat ttaatcaaag
     3421 aaattattag tttgagaaaa gaacttcata aaaaataata ctagagtatt atcattgtta
     3481 ttaacataga ggaggaaaac ataatggtga agattggttt gttttgtgca gcaggttttt
     3541 ctactggtat gcttgtaaat aatatgaaaa ttgcagcgca atctagtgga gttgaggcag
     3601 aaatagaggc gttttctcag tctaaattag cggattatgc gccaaatata gatgttgcac
     3661 tattgggtcc acaagttgct tatacattag ataaatcaaa agaaatttgt gataagtgtg
     3721 atgttccgat agctgttatt ccgatgatgg actatggtat gttagatggg aaaaaagtat
     3781 tagatttggc cctatctttg attagtgggt aagaaaagga gatttattat gtcaaagatg
     3841 gatgttcaga aaatcattgc accgatgatg aagtttgtga atatgcgtgg cattatagct
     3901 ctaaaagatg ggatgttagc aattttacca ttgacagtag ttggtagttt gttcttgatt
     3961 atgggacaat tgccgttcga aggattaaat aagagcattg ctagtgtttt tggagctaat
     4021 tggacagagc cgtttatgca agtatattca ggaacttttg ctattatggg tctaatttct
     4081 tgtttttcaa ttgcctattc ttatgctaag aatagcggag tagaggcttt accagctgga
     4141 gttctatctg tatctgcatt ctttattttg ctaagatcgt cttatatccc taaacaaggt
     4201 gaggcgattg gggacgctat tagtaaagtt tggtttggag gccaaggaat tatcggtgct
     4261 atcattatag gtttggtagt aggaagtatt tataccttct ttataaagag aaaaattgtt
     4321 attaagatgc cagaacaagt tccacaagct attgccaaac agtttgaagc aatgattcca
     4381 gcatttgtaa ttttcttatc ttctatgatt gtatatattt tagcgaagtc attgactaat
     4441 ggcggaacat tcatagaaat gatttattct gctattcaag ttccgttgca aggtttaact
     4501 ggatctttgt atggtgctat tggaattgca ttctttatat catttttgtg gtggtttggt
     4561 gttcatgggc aatcggtagt aaatggagta gtgacagctc tgcttttatc taatcttgat
     4621 gctaataaag ctatgttagc ctctggtaat ctatcattag aaaatggtgc acatattgtt
     4681 actcaacaat ttttagattc atttttaatt ctatcaggtt cagggattac gtttggtctt
     4741 gtagttgcca tgctttttgc agcaaaatca aaacaatacc aagccttagg aaaagttgca
     4801 gcttttccag caatatttaa cgtaaatgag ccagttgtat ttggatttcc gattgtcatg
     4861 aatccagtta tgtttgtacc tttcattctt gttcctgtac ttgcagctgt gatagtatat
     4921 ggagctattg caacaggttt catgcaacca ttctcagggg taacattgcc ttggagtaca
     4981 ccagctattc tatcaggatt tttggtgggt ggatggcaag gtgttgtgac tcagttatta
     5041 gtattggtga tatctacagt ggtttacttt ccattcttta agatacaaga tcgtttagct
     5101 taccaaaatg aaatcaaaca atcttagagg tatttgtgtg ttactgttaa actcacacat
     5161 ttgtgctaaa aattagagag ttaaaatttt tctagttaaa agcttgaaaa tttctataaa
     5221 aatcggtatt atattttcga aagaaataaa aatattttcg aaagaaaggt gcttacgatg
     5281 gtaaatacag aagtagcaag aacaacaatc aagacagaat attttggcag ccttactgaa
     5341 aggatgaaca aatatcgaga agatgtttta aataaaaaac cttatattga tgctgagaga
     5401 gcagttctag caacacgcgc ctatgaacga tacaaggaac aacctaatgt cctaaaacgt
     5461 gcatatatgc tgaaagaaat tttggaaaat atgtctatct atattgaaga agaatctatg
     5521 attgcgggaa atcaagcttc ttccaataaa gatgctccta tttttccgga atatacgcta
     5581 gaatttgttc tcaatgagtt ggatcttttt gaaaagcgtg atggagatgt tttctatatt
     5641 acagaagaaa caaaagaaca acttagaagt attgctccgt tttgggaaaa taataattta
     5701 cgtgctagag ctggtgcctt attacctgaa gaagtgtcag tttatatgga aacaggattc
     5761 ttcggtatgg aaggtaagat gaattctgga gatgctcact tagcagttaa ctatcagaaa
     5821 cttttgcaat ttggtttaag aggttttgaa gagcgggctc gtaaagcgaa ggtagctcta
     5881 gatttaacag atccagcaag tattgataaa tatcattttt acgactctat atttatcgta
     5941 atcgatgcta ttaaagtata tgcaaagcgc tttgttgctc ttgctaaaag tttagccgaa
     6001 aatgcaaatc ctaaacgtaa gaaagaatta cttgagattg cagatatttg ctctagagtc
     6061 ccatatgaac cggcaactac ttttgcagaa gctattcaat cagtttggtt tattcaatgt
     6121 attttacaaa ttgaatctaa tggccactct ctttcatatg gccgttttga tcaatatatg
     6181 tatccatata tgaaggctga tttagaaagt ggtaaagaaa cagaagatag cattgttgaa
     6241 cgtctgacaa atctttggat taagacaatt acaattaata aggttcgcag tcaatcacat
     6301 acattttctt cagcaggaag tcctttatat caaaatgtta caattggtgg acagactcga
     6361 gataagaagg atgctgttaa cccattatct tatttggtat taaaatcagt tgcacaaacc
     6421 catctaccgc aacctaatct aactgtacgt taccatgcag gtttagatgc tcgtttcatg
     6481 aatgagtgta ttgaagtgat gaaacttggt tttggtatgc ctgcatttaa taatgatgag
     6541 attattattc cttcttttat tgcaaaagga gtattggaag atgatgctta tgattacagt
     6601 gccattggat gtgttgaaac ggcagttcca gggaaatggg gctatcgttg cacaggtatg
     6661 agttatatga acttccctaa ggttctactt atcacgatga atgatggaat tgatccggct
     6721 tcgggtaaac ggtttgcacc aagctttggt cattttaagg atatgaagaa cttttctgaa
     6781 ttagaaaatg cttgggataa aacactaaga tatttgacac gaatgagtgt tattgttgaa
     6841 aattctattg atttatcatt ggaacgagaa gttcctgata ttctatgttc agcattgact
     6901 gatgattgta ttggtcgtgg aaaacacctt aaagaaggtg gagcagtata tgattatata
     6961 tcaggattgc aagttggaat tgcaaatttg tcggattcat tagctgcaat taaaaaattg
     7021 gtgtttgagg aagaacgtat aagcccaagt cagctttggc atgcactgga aacagattat
     7081 gccggagaag aaggtaaggt cattcaagaa atgttgattc atgatgcacc taagtatggt
     7141 aatgatgatg attatgctga caaattggtt actgctgctt atgacattta tgttgatgaa
     7201 attgctaaat atcctaatac acgttatgga agagggccta ttggaggaat tcgttattca
     7261 ggaacatctt ctatatcagc caacgtaggg cagggacgtg gaacattagc aactccagat
     7321 ggacgcaacg cgggtacacc gttagcagag ggttgttcac catcacataa tatggatcaa
     7381 cacggcccta catctgtttt aaaatctgtt tcaaaattac caacagatga aatcgtaggt
     7441 ggggttctct taaatcagaa agtaaatcct caaacgttag ccaaagaaga agataaatta
     7501 aaactaattg ctttgttacg aacattcttt aatcgtttac atgggtacca tattcaatac
     7561 aatgttgttt ccagagagac gttgattgac gctcagaaac atcctgaaaa acacagagac
     7621 ttaattgttc gtgttgcagg atactctgca ttcttcaatg ttctttctaa ggcaacccaa
     7681 gatgacatta taggacgtac tgagcatact ttgtaaaata aagaggttct ttttatggaa
     7741 tttatgcttg acacattaaa tttagatgag attaaaaagt ggtctgaaat tttgccgcta
     7801 gctggggtaa cttcaaatcc cactattgca aaaagagagg gttctattaa tttttttgaa
     7861 cgaatcaaag atgtaagaga attgattggc tctacaccct ctattcatgt tcaggtgatt
     7921 tctcaagatt ttgaaggcat cttaaaggat gctcatgaaa ttcgaagaca agcaggagat
     7981 gatatattta tcaaagtacc tgttactcca gctggattac gtgcaataaa ggtgctaaaa
     8041 aaagagggct accatatcac tgcaacagct atttatacag ttattcaggg attattagct
     8101 atcgaagcag gagcggatta cctagctcca tattataata gaatggaaaa tctgaacatt
     8161 gattcaaatt ctgtcattcg tcaattagct cttgctattg atagacagaa ctctcctagt
     8221 aagattttag ctgcatcctt taaaaatgta gcacaagtaa ataatgcttt agctgcaggt
     8281 gcgcatgctg ttacagcagg agcagatgtt tttgaatcag ctttcgccat gccatctatc
     8341 caaaaggcgg ttgatgactt ttctgacgac tggtttgtta ttcaaaatag tcgttccatt
     8401 tagatagaga ggaaatacat atgagaattt ttgctagtcc ttctagatat attcaggggg
     8461 aaaatgcctt gtttgaaaat gccaaatcaa ttttggattt gggaaattgc cctattctat
     8521 tatgcgatca gttggtttat gatattgttg gaaaacgatt tgaagattat ctacataggt
     8581 atggtttcca tattgttctg gcgctattta atggtgaagc ttctgacaat gaaatcaatc
     8641 gagttgttgc cttggctgag aaagaaaatt gtgatagtat tatcggtctt ggtgggggaa
     8701 agacgattga tagcgcaaaa gctattgcag atttgattga aaagcctgtt attattgctc
     8761 caacaattgc atcgaccgac gcacctgtat ctgctttatc tgttatttat acagatgaag
     8821 gtgcatttga tcattatcta ttttattcta aaaatccaga tttagttttg gttgatacaa
     8881 aagttatttc acaagcccct aagcgtttat tagcgtctgg tattgcagat ggtttagcaa
     8941 cttgggttga ggcgcgtgcg gttatgcagg caaatggaaa aactatgttg ggacaacagc
     9001 aaacattggc tggagttgca attgcgaaga aatgtgaaga aacgctgttt gcagatggtt
     9061 tacaggctat ggcagcttgt gaagctaaag tggtgacacc agcattagaa aatattgttg
     9121 aagctaatac tttattgagt ggtctaggtt ttgaaagtgg aggattagct gcggcgcatg
     9181 caattcataa tggttttact gcattgacag gtgacattca tcatttaaca catggtgaaa
     9241 aagtagctta tggaacttta gtacaactat tattggaaaa tagacctaaa gaagaacttg
     9301 ataagtatat tgagttttac aaaaaaattg gtatgccaac aactctaaaa gaaatgcatt
     9361 tggatcaagt tggatatgat gatttaataa aagttggtaa acaagcaact atggagggtg
     9421 agacaattca tcagatgccg tttaagattt cgccttcaga tgttgctcaa gctattatcg
     9481 ctgtagatgc ctatgtaaat tcaaaataaa caataaggac tactgttttc caaatggtag
     9541 tcttttattg atccctgtat tgaattctat agaagattga aataggatga gaacaaatcg
     9601 attgggaaag taaaattaat ttctataaat gttttagcaa ttgtttcgta ctatttcaga
     9661 ttcagtctac tatacgttct tcataaatca aaaagcgaca taggtagtcg gctatttatt
     9721 gtgaatacat taattagcat tccagtttta tcttcggtct aaaataagta ttttgtgcta
     9781 tacgagataa gcttcttgac ttactccttg atttactgca taacaatggg ataaaaagtg
     9841 ggagatagag caattcatag tcatcaaaat taatgagata cagtatacag tttttccttt
     9901 aaacacattt caaattccct caaaaatggt ataatagtaa catcacaaaa ttggagagag
     9961 accatgagtt tttacaatca taaagaaatt gagcctaagt ggcagggcta ctgggcagaa
    10021 catcatacat ttaagacagg aacagatgca tcaaaaccta agttttatgc gcttgatatg
    10081 ttcccttatc cgtctggagc tggtctgcac gtaggacacc cagaaggtta tactgcaacc
    10141 gatatcctca gtcgttacaa acgtgcgcaa ggctacaatg tccttcaccc aatgggttgg
    10201 gatgcttttg gtttgcctgc agagcaatac gctatggata ctggtaatga cccagcagaa
    10261 tttacagcgg aaaacattgc caacttcaaa cgtcaaatca atgcgcttgg attttcttat
    10321 gactgggatc gtgaagtcaa tacaacagat ccaaactact acaagtggac tcaatggatt
    10381 ttcaccaagc tttacgaaaa aggcttggcc tatgaagctg aagtgccagt aaactgggtt
    10441 gaggaattgg gaactgccat tgccaatgaa gaagtgcttc ctgacggaac ttctgagcgt
    10501 ggaggctatc cagttgtccg caaaccaatg cgccaatgga tgctcaaaat cacggcttac
    10561 gcagagcgct tgctcaatga cttagatgaa ctagattggt cagagtctat caaggatatg
    10621 caacgcaact ggattggtaa atcaactggt gccaatgtaa ctttcaaagt aaaaggaaca
    10681 gacaaggaat ttacagtctt tactactcgt ccggacacac ttttcggtgc gactttcact
    10741 gtcttggctc ctgaacatga attagtagac gctatcacaa gttcagagca agcagaagct
    10801 gtagcagact ataaacacca agccagcctt aagtctgact tggctcgtac agaccttgct
    10861 aaagaaaaaa caggggtttg gactggtgct tatgccatca accctgtcaa tggtaaggaa
    10921 atgccaatct ggattgcaga ctatgtcctt gctagttatg gaacaggtgc ggttatggct
    10981 gtgcctgccc acgaccaacg tgactgggaa tttgccaaac aatttgacct tccaatcgtc
    11041 gaagtacttg aaggtggaaa tgtcgaagaa actgcctaca cagaggatgg cctgcatgtc
    11101 aattcagact tcctagatgg actcaacaaa gaagacgcta ttgccaagat tgtggcttgg
    11161 ttggaagaaa aaggctgtgg tcaggagaag gttacctacc gtctccgcga ctggctcttt
    11221 agccgtcaac gttactgggg tgagccaatt ccaatcattc attgggaaga tggaacttca
    11281 acagctgttc ctgaaactga attgccgctt gtcttgcctg taaccaagga tatccgtcct
    11341 tcaggtactg gtgaaagtcc actagctaac ttgacagatt ggcttgaagt gactcgtgaa
    11401 gatggtgtca aaggtcgtcg tgaaaccaac actatgccac aatgggctgg ttcaagctgg
    11461 tactacctcc gctatattga tccacacaat actgagaagt tggctgatga ggacctcctc
    11521 aaacaatggt tgccagtaga tatctacgtg ggtggtgcag agcatgctgt tcttcacttg
    11581 ctttacgctc gtttctggca caaattcctc tatgacctcg gtgttgttcc gactaaggaa
    11641 ccattccaaa aactctttaa ccaagggatg attttgggaa caagctaccg tgaccaccgt
    11701 ggtgctcttg tggcaaccga caaggttgaa aaacgtgatg gttccttctt ccatgtagaa
    11761 acaggggaag agttggagca agcgccagcc aagatgtcta aatcgctcaa gaacgttgtt
    11821 aacccagacg atgtggtgga acaatacggt gccgataccc ttcgtgttta tgaaatgttt
    11881 atgggaccac tcgatgcttc gattgcttgg tcagaagaag gattggaagg aagccgtaag
    11941 ttccttgacc gagtttaccg tttgattaca agtaaagaaa tccttgcgga aaacaatggt
    12001 gctcttgaca aggtttacaa cgaaacagtc aaagctgtta ctgagcaaat tgagtctctc
    12061 aaattcaaca cagctattgc ccaacttatg gtctttgtca atgctgctaa caaggaagat
    12121 aagctttatg ttgactatgc caaaggcttt attcaattga ttgcaccatt tgcacctcac
    12181 ttggcagaag aactctggca aacagtcgca gaaacaggtg agtcaatctc ttatgtagct
    12241 tggccaactt gggacgaaag caaattggtt gaagatgaaa ttgaaattgt cgtccaaatc
    12301 aaaggaaaag ttcgtgccaa actcatggtt gctaaagatc tatcacgtga agaattacaa
    12361 gaaatcgctt tagctgatga aaaagtcaaa gcagaaattg acggtaagga aatcgtgaaa
    12421 gtaattgcgg taccgaataa actcgttaat atcgtcgtta aataacgagt ttattagctc
    12481 tatctgccac cttcaatagt ccactggact attgaagcca actaaattag ttaacattgt
    12541 tgtgaaataa aaagaagtaa ctctagagta tgaactttag agttactttt agaataggtc
    12601 agaatgaata gattagtgaa cgatagcagg aagtgtgaaa ttttattatt taagatttct
    12661 attattgtag tgtcagtata gtattagtaa tgtcaatagt gggtgcatat tattttaaaa
    12721 attgtctttg ggacaaggaa agtttaaatt tgacactcac tttagacact ctctttgcag
    12781 tttttattac tttctttagt ttttcaaatg ataaatcaag caatattttt ggaatatctc
    12841 caaatgaaat tata
//
LOCUS       DAVMAH010000053        12516 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVMAH010000053 DAVMAH010000000
VERSION     DAVMAH010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12516
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.053"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(<1..269)
                     /locus_tag="VYO94_001668"
     CDS             complement(<1..269)
                     /locus_tag="VYO94_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV1760273.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSN"
     gene            512..805
                     /locus_tag="VYO94_001669"
                     /pseudo
     CDS             512..805
                     /locus_tag="VYO94_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            912..1263
                     /locus_tag="VYO94_001670"
                     /pseudo
     CDS             912..1263
                     /locus_tag="VYO94_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1539..2845
                     /locus_tag="VYO94_001671"
                     /pseudo
     CDS             1539..2845
                     /locus_tag="VYO94_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2885..3895)
                     /gene="tsaD"
                     /locus_tag="VYO94_001672"
     CDS             complement(2885..3895)
                     /gene="tsaD"
                     /locus_tag="VYO94_001672"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV1760274.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKTFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEEYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(3885..4322)
                     /gene="rimI"
                     /locus_tag="VYO94_001673"
     CDS             complement(3885..4322)
                     /gene="rimI"
                     /locus_tag="VYO94_001673"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV1760275.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            complement(4319..5002)
                     /gene="tsaB"
                     /locus_tag="VYO94_001674"
     CDS             complement(4319..5002)
                     /gene="tsaB"
                     /locus_tag="VYO94_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV1760276.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVAPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            5180..5365
                     /gene="cibA"
                     /locus_tag="VYO94_001675"
     CDS             5180..5365
                     /gene="cibA"
                     /locus_tag="VYO94_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV1760277.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            5368..5520
                     /gene="cibB"
                     /locus_tag="VYO94_001676"
     CDS             5368..5520
                     /gene="cibB"
                     /locus_tag="VYO94_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV1760278.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            6338..6571
                     /locus_tag="VYO94_001677"
     CDS             6338..6571
                     /locus_tag="VYO94_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV1760279.1"
                     /translation="MIYKVFYQETKEHSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6573..8252
                     /locus_tag="VYO94_001678"
     CDS             6573..8252
                     /locus_tag="VYO94_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1760280.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQGEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(8631..10544)
                     /gene="mnmG"
                     /locus_tag="VYO94_001679"
     CDS             complement(8631..10544)
                     /gene="mnmG"
                     /locus_tag="VYO94_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV1760281.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(10554..11009)
                     /locus_tag="VYO94_001680"
     CDS             complement(10554..11009)
                     /locus_tag="VYO94_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1760282.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNRKLLVTKDKGKYYIIGGA
                     IQVNEKTEDAVVREVKEELGVKSQAGQLAFVVENRFEADGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(11150..12271)
                     /gene="mnmA"
                     /locus_tag="VYO94_001681"
     CDS             complement(11150..12271)
                     /gene="mnmA"
                     /locus_tag="VYO94_001681"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV1760283.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLATAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
BASE COUNT         3548 a         2947 c         2475 g         3546 t
ORIGIN      
        1 ttatttgaac attgagtaca atcaacatag gcaatatcta aatttttata atcatcaata
       61 acctttgaat ctctagatac gattatcaaa ataggatata gagacatcct tctgatctgc
      121 tttttacaaa gtccaattat atgcggatct atacctccac aatgtccatt attataccta
      181 actataatat gagccgaaaa cactatatcc ttaatgtctc catatccatc agggatatta
      241 atatttattt ttccacaact atattgcatt gtaaccatct ccttaaacga cgcattatga
      301 tatttgatag agaaattttt atgaataact caataatttt atagtaaatc atgcttatat
      361 ctcaaagata cctattttct cttatctcga ccttctccaa agaattgcta taatactatt
      421 acaaatacat ctgcactaca cttcaaattt tagcactgta taaaaacgtt tcaacacact
      481 aactttaaga aaacttccac tattaattga aaaagttgat agagataaat taaagatcta
      541 tattgaaact catcccgatg cttatttgac tgaaatagct gctgaattca actgtcctcc
      601 aacaactatt cattacgctc taaaggctat gggatatagt ctaaaaaaga gccgtaccta
      661 ctgcgaacaa gacccagaaa aagtaaatcg gttccttaaa gaattgaatc acttaagcta
      721 cctgactcct atttatattt atgagacagg ggttgagacc tatttttatc tcgaatatga
      781 tcgagccttg agcaggcagt tagtctctct ggaagaagat ataattattt gaattaagat
      841 cgagacaacg cacaccagag attgcgatac tgttatagaa gtactaatgc ccttttttgt
      901 ttcaatatac tatggctccg atgacctata aagatacgat gacgagtgac tttttcgaag
      961 cttgcttcca aaaattctta ctacctactt tagatacacc atcccttatc attatggaca
     1021 atgcaaggtt tcacagaatg aacatgtgta aggagcaggg catagactgt taccacttcc
     1081 tacctattca cccgagtata atcccattga gaaaatatgg gcttacatca aaaacatctc
     1141 agaataatat tgtcaaatta cgatgctttt cttgaggcac ttttgtccta ttcttgtttc
     1201 agccgactat actccgttat tgggcagcta cggaacagtc gatgggacga tggggggaca
     1261 taaaaaaatc ctccagtttt gttttttata acagtatact ggagaattga caatctcggt
     1321 agatacctcg ttatagcgcg gttacttatt aggcagttac aaaacaactg tgaacagaaa
     1381 acattccaga gtcagacaag actttggaat gttttggctc tataatttct gtagtgggta
     1441 atcccacccc aggaagtata gggtcgtttc ttgtagaaaa aaagccccat atgacctata
     1501 atgaaaatcg tctaaccaac tcattagaaa ggggtcatat ggaacaactt aagaatacca
     1561 cagatttgct cggattggaa gacaaaaata tcaaaatctt gtctgttctg aaataccaaa
     1621 cccatctagt cgttcaggca aagttggatt cccccgctcc tccttgtcct cattgtcaag
     1681 ggaagatgat caaatacgac ttccagaaag cctctaaaat tccgcttctc gactgtcagg
     1741 gtttacccac ggtactgcat ctcaaaaagc gccgctttca gtgcaagaat tgccttaagg
     1801 tggtcgtttc tcaaacatcc attgtcaaga aaaattgcca gatttccaac atggtgagac
     1861 aaaaaatcgc tcagctcctc cttgaaaagc agtctatgac tgagattgcc cacagattgg
     1921 cggtctcaac ttccaccgtc atccgaaaac tgagggaatt taagtttgaa accgattgga
     1981 ccaagttgcc aaaagttatg agttgggatg agtatagctt caaaaagagc aaaatgagct
     2041 tcattgccca agattttgag tccaaatcca tcctcgcaat tttagacggg cgaactcatg
     2101 cggtgattcg aaaccatttc caacgctatc agagagaggt tcgggagctg gtcgaggtca
     2161 tcaccatgga catgtacagc ccttattatc ggctcgctaa gtaactcttt ccaaaggcga
     2221 agattgttct tgaccgcttc cacattgtcc aacatctgag ccgagctatg aaccgagtac
     2281 gaatccaaat catgaacaaa tttgaccgaa aatccttgga gtatcgggcg ctcaagcgct
     2341 tttggaaccc tcgctttttc gtttctaggc tcgggctaaa tcagtccact ggactgattt
     2401 actacaccag gatagcttca agctctgtca gaaacgattc tatcagccca cgtttcgaat
     2461 gcacttaacc catcgggaag tacgagataa gctgctttct tactctgagg gattacaggt
     2521 tcactacgaa ctctatcaac tcctgctctt tcattttcaa gagaagaatg ccgaccattt
     2581 ctttggattg attgagcaag aactgccaac ggttcatccg ctttttcaaa cggtcttttg
     2641 gactttttta agggatagag ataagattat caacgcactt aagctgcctt attccaacgc
     2701 taaacttgaa gcgaccaata atttgattaa ggttatcaag cgcaaagcct ttggtttccg
     2761 gaactttaac aattttaaaa aacggatttt gatgactttg aacatcaaaa aagagagtac
     2821 gaatttcgta ctctccagat tgtaactttt cgcctaccca ctacacttga caaagagcca
     2881 ctctttattc catggtatca aaggcaagac ttggtttggc attgaggtcc cagcctgcga
     2941 agttttcttt gttccactcg ctgacgctgg cataggcaat catacctgca ttgtctccgc
     3001 agagtcgcag aggggggatg ataaccttga catctgtgat ttcggctgct aagcgttctc
     3061 tgagaccttt attggctgcc acaccacctg ccacaactag ggttttaaca ggatattcct
     3121 ccaaagcctt cttggttttt gccatgagaa tgtccataac tgctgcttgg aaggaagcac
     3181 acaaatcttc tgtagacagg ctttctccct tttgctcggc attgtgatga agattgataa
     3241 aggctgactt caaaccagag aatgaaaact ccagattatc ttccttaatc atggcacggg
     3301 ggaaatcata aatatcctgc ccctgatgag ccagctcgtc aatctcacga cctgcaggat
     3361 aggtcaagcc catgacacgg ccgaccttat cataggcctc gccaaccgcg tcatctcgtg
     3421 tctccccaac aatcttgtaa tcgccagcct cagaaacata gaccaactct gtgtggccac
     3481 cgctgaccaa gagtgccaac aaaggaaact ccaaaggctc cacactctga gcggccatga
     3541 ggtgcccagc catgtgatta acagggatca gcggaagtcc gtgagcccaa gcaaaggtct
     3601 tggcagctga caagccaact agcaaggctc cgactaagcc cggtccatag gtaaccgcaa
     3661 cagctgtcac gtcctcttcg gtaatccctg cttctgccaa tgcctcctcg atacaggctg
     3721 taatgacctc gacatggtga cgactggcta cttcgggcac tacgccacca aaacgtttgt
     3781 gactctcaat ttgactagca atgacattgg acaagagctc atcgtcgttt ttcaagacgg
     3841 cgacactggt ctcatcacag gatgtctcaa atgctaaaat atatctatcc ttcatctatt
     3901 tctctcttca tgataatggc gtcctcgact gggtcatggt agtaggcctt tcgctcagcg
     3961 ataactgcca tcttttcttt cttgtaaaat gcttgcgctc gttgatttga ctgtctgact
     4021 tcgaggaaaa tttccttgtc tgtcggcaat tgagcaaaca aggctgacgc aattccctga
     4081 ccctgataag ctcctttgac agcgatttgc aggacttctg cttcaaaaag attctcctgc
     4141 acagctagaa atccaatcac ttctgcccca tcataagcca atgcatacca agtctggtct
     4201 tgggacagat ctgcttggat ttgctccaga gtccaaggac tgactaggta aacagctgcc
     4261 ataacagcgt agatggcttg agctaggtca ggctgttgtt gaattcgctt gatttctatc
     4321 ataggcgttt aatgtaggac tcaccagact cggtatggtt cttgagccag ttttcctcag
     4381 cctcgactcg tttgaggtaa tttggcacaa aatcatgcaa ggagtctgct tccttgtccc
     4441 aagctaaaag agcaagattg gctgcattag gcaaggtttc tttataatta gtccttggca
     4501 agtgttcttg aatctgctcc acaaaggggg caacttctcc gacaaaggtt acctgactag
     4561 cacccttgac tttttctagc acctcttcaa aagataggtg cgcttctggc atgacaggtt
     4621 tagcattttc ataaaatcct gcataaacat tgttgcgacg cgcatccatc aaaggaacga
     4681 acaagccttc ttgttgatat ggcaccagag ccaagaggct agacatacca actaactcaa
     4741 tgttcagagt atgagtcaag gtcttggcag tggctaccgc gattcgcaag cctgtgtagc
     4801 tacctggccc ttccgccacc acgattcggt ccaaatcctt gggcgtccag tccaaactct
     4861 ccatcaaaaa atcaatggct ggcatgaggg taatactgtg atttttcttg atattaatcg
     4921 tcgtctcagc aagaacctgc ttgtcctcta aaatagccag agaaagagcc ttgctggacg
     4981 tatcaaaagc taatactttc ataacacatt cctatctttt tgtctgctta ctattatact
     5041 acaaaagctg gcacatggga attttctttg cccccagaca agagtgccct cacttaacta
     5101 aaaataatta aaaaaaatgc tcacttttcc ttttcttttc cgaatataaa agtgaacaag
     5161 aaaaaaggag gaaagttcaa tgacaaattt tgacattctt gacaatcaat ttttatcctt
     5221 atctgaaaat gaattatcag atattgatgg cggtctcgct cccttggtta tctttggagt
     5281 agcagtatct tggaaggcta ttgcaggtgg aacagcactt ataggttctg gtttagcagc
     5341 tggttatttt ttaggaggag attaactatg atgaaagatt tgaacaacta tcgtgaaatt
     5401 tctaataagg aattgcaaga aatcaagggt ggctttggtg taggtgttgg tatcgcttta
     5461 tttatggcag gttataccat tggaaaagac cttcgtaaaa agtttggtaa gtcatgctag
     5521 ataagaaaca catttttaga aggataaatt ttattgtctt catctcttac agtttgctca
     5581 gcattctcaa tgatttgaac attactacta tccctttacc attcgattta tctgtttgta
     5641 ttgttttatt tttatgcttc aactctattt ttgagcagaa caatgactcc cataaaaata
     5701 ataagctttg aaaattccat tgtcatgtca tgttagaaaa atgcaaagac cacctcatct
     5761 tgatagatgg ggtggaattt tcgtgtcgta aatctactat ctctacatcc ccaaacaaaa
     5821 aaccccagca taagcagggc atctaagcat ttaatccaaa gtaaaataca aaccaaacga
     5881 cataggtcac gaggaggaga aaaagcgagt agagagtcac aaaggtaatt ttccacaaga
     5941 acttggtttg tcatcgttcc agtttggcaa atagaagatt tcctccataa acgcaagcaa
     6001 caaaaacgat aaaagctaac aaacgaactc cgatagcaaa agcaaataag ttatacatag
     6061 ggcaacctcc ttgacttaaa atctatatgg aattatgaca agtaataaac ttcacttccg
     6121 ttatcaacat aacacatttt ctttattttt gcaaacgctt accgaagaaa tcgtccccta
     6181 actttctcgt ttccgtcttt tactaatttt tcattttgtg gtataattga aataattgta
     6241 acgaatcaag gtcaatctag acacaaaatg gaatgaaatc aagcaaatat ctgctaaaag
     6301 tttggaataa gctgacctgt aaatagaaag gaactatatg atttacaaag ttttttatca
     6361 agaaacaaaa gaacatagcc cacgccgtga aacaacacgc gcgctttacc tagacatcga
     6421 tgccagctca gaacttgagg gccgtatcac tgctcgccaa cttgtcgaag aaaatcgccc
     6481 agagtacaat atcgaatata tcgaactctt gtctgacaaa ttgctcgatt acgaaaaaga
     6541 aactggcgcc ttcgaaatta cggagttcta atatggccta cactcttaaa cctgaagaag
     6601 tcggcgtttt tgccatcggt ggtctaggag aaatcgggaa aaacacttac ggaatcgaat
     6661 accaaggcga gattatcatc gtcgatgctg ggattaaatt cccagaagat gacttgcttg
     6721 gtatcgacta tgtcattcct gactactctt acatcgtaga caatatcgac cgcgtcaagg
     6781 ctgttttaat cacacacgga cacgaggacc acattggtgg gattccgttc ctactcaagc
     6841 aagcaaatgt ccctatttat gctggaccgc ttgccttggc tttgatccgt gggaaactcg
     6901 aagaacacgg cctcttgcgc aacgccaaac tttacgaaat caaccacaac accgagttga
     6961 cctttaaaaa tctcaaggca actttcttta gaacgactca ctctattcca gagcctttgg
     7021 ggattgtcat tcatactcct caagggaaaa tcgtctgtac gggtgacttt aagttcgact
     7081 ttactccagt tggagaacct gcggacttgc atcgtatggc tgcgcttggt gaagaaggcg
     7141 tgctctgtct cctgtctgac tcgacaaatg cggaagtacc aacctttacc aactctgaaa
     7201 aagtcgttgg tcagtccatt atgaagatta tccaaggtat tgaaggacgt atcatctttg
     7261 catcctttgc ctcaaatatc ttccgtctcc agcaggcaac agaagctgct gttaagactg
     7321 gacgcaagat tgcggtcttt ggtcgttcta tggaaaaggc cattgtcaac ggaatcgatc
     7381 ttggctacat caaagctcct aagggaacct ttatcgagcc aaatgaaatc aaagattatc
     7441 ctgcaggaga agttcttatc ctctgtacag gtagtcaggg tgagcctatg gcagccctct
     7501 ctcgtatcgc caacggaacc caccgtcaag tacaattaca accaggtgat accgttatct
     7561 tctcttctag tcccatccct ggaaacacta ctagcgtcaa caagctgatt aacatcattt
     7621 ctgaagctgg tgtcgaagtt atccacggta aagtgaacaa tatccataca tctggacacg
     7681 gtggtcagca agagcaaaaa ctcatgctct gcttgattaa gccaaaatac ttcatgcctg
     7741 tccacggtga ataccgcatg caaaaagtcc acgctggact agcagtggat actggtgttg
     7801 agaaggacaa tatctttatc atgagcaatg gcgatgtgct tgcccttact gctgactcag
     7861 ctcgtatcgc aggtcatttc aacgcccaag atatctatgt cgatggaaat cgtatcggtg
     7921 aaattggcgc agctgtcctc aaagatcgtc gcgatctatc tgaagacggt gtcgttctgg
     7981 cagtcgcaac tgttgacttc aaatcgcaga tgattctatc tggtccagac atcctcagcc
     8041 gaggctttgt ctacatgaga gagtctggcg acttgattcg ccaaagccag cgtatcctct
     8101 tcaatgccat tcgtatcgca ctgaaaaata aggatgctag cgtgcaatct gtcaatggtg
     8161 ccattgtcaa cgctattcgc cccttcctct atgaaaatac cgaacgtgaa ccgatcatca
     8221 tcccgatgat cctcacacca gatgaagaat aatactcttc aaaccacgtc agcttcgcct
     8281 tgccgtatat atgttactga cttcgtcagt tctatccaca acctcaaaac tgtgttttga
     8341 gctgacttcg tcagttctat ctacaacctc aaagcagtgc tttgagcaac ctacggctag
     8401 cttcctagtt tgctctttga ttttcattga gtacaagtca acaaaacagc cccgtcttcg
     8461 gagctgtttt tctctatgct ttcttttgag attaaaactc aatgaaaatc agaccagaag
     8521 gctaagcgaa agcataactt gagttagctc ccatagttcg ggaaactatg ggaggctgga
     8581 gatgaatcaa agccaagctt tgaactcatt cgtaagaagc cgacgacgta tcattttgat
     8641 ttttgaagag ttttagaaat actacgattt ttaccttcca gatacaccat caaaatagaa
     8701 atatctgctg ggtttactcc cgaaatacgg ctggcttggc cgatggtttc tggattgatg
     8761 agtttgaact tctgacgagc ttccgtcgca atagaatcga tgtcatccca gtcaatattg
     8821 gctggaatgc gtttttcttc catacgtttc atcttggcaa cctgatccat ggcttttgaa
     8881 atatagcctt cgtacttgat ttctgtttca atcaattcga taatcttgtc atccaagtct
     8941 tctgcagctg gtccgatgaa ggccaccaca tcttggtaag aaacttctgg acggcgaagg
     9001 aattccttgg ctgtcaccgc atctgtcaac ggcttgaagc ccatttcctc aaccttagca
     9061 ttggtttcct tgactggctt gagtttgata ctgtctaggc gtttcatctc attatcaaat
     9121 tgatttttct tgatttcaaa acgagcccag cgttcatcat ccacaaggcc aatctcgcgt
     9181 cccatctcag tcaagcgcat atcagcattg tcatggcgaa gaatgagacg atattcagca
     9241 cgactggtca agagacggta aggttcaatg gttcccttgg tcaccaagtc gtcgatcatc
     9301 accccgatat aaccgtcact tcgcttcaaa atcaactcag gcttaccttg gattttcaga
     9361 gccgcattga tacccgcgat aatcccttgg cctgctgcct cttcgtaacc tgacgttcca
     9421 tttgtctgac cagcagtgaa gagacctgag attttcttgg tttccagagt cgcacgcaac
     9481 tgatgaggca agaccatatc atactcaata gcataacctg tccgcatcat ctctgcattt
     9541 tccaaacctt tgatggaatg aaccaagtca cgctggacat cctcaggcag actggttgaa
     9601 agtccttgca catagacttc ctcagtattg cgcccttctg gctcaaggaa gagttggtga
     9661 cgttccttgt ccgcaaagcg cacaatcttg tcttcaatcg acggacagta acgaggcccc
     9721 actcccttga ccacacctgt aaacataggc gcacggtgga ggttgttttg gataatctca
     9781 tgactggtac cattggtgta ggtcaaccag catggcactt ggtccttgac ataatcctca
     9841 tcacgtgaag tgtatgagaa gtgattaggt gcttcatctc ctggttggat ttctgtcacg
     9901 tcgtagttga tagaagaggc cttgacacgt ggaggggttc ctgtcttgaa acgaccgatt
     9961 tcgaggccca gttccttgag attgtcagct aggttaatag aagccaagct gtggttagga
    10021 cctgatgagt acttgaggtc tccgatgata atttccccac ggagagcagt ccctgtcgtc
    10081 acaataacag ccttagcagc atattcttga tgggtggctg tacgcacacc gacaaccttg
    10141 ccatcttcca ccaaaatctc atcaatcatg gtttgacgaa gggtcagatt ttcttggttt
    10201 tcaaccgtct tgcgcatctc cttagagtaa agttccttgt cagcctgcgc acgaagggca
    10261 cggacagctg gccccttccc tgtgtttagc atcttcatct ggatgtaagt cttgtcaatg
    10321 gttttggcca tctcgccacc gagggcatcg acttcacgca cgacaatccc cttggcagaa
    10381 ccaccgatag agggattaca aggcatgaaa gccagcattt caatattgat ggtcgcaagc
    10441 aggaccttac agcccatacg gctagcggcc aaggaagcct caaccccagc gtgtcccgca
    10501 ccaattacaa taatatcgta ttcttcagta aaatgataag tcatgtttct ctcctattcc
    10561 tcaagatgaa tgtgtcttag ttggccttcc caatctggta gggccgtttt taaaaaggct
    10621 ggaactagct ggatatcctc aagcttatcc aagtcaatcc actcacaggg ctgccttttc
    10681 tcatcttcct gcatggtcaa cggggcatct tcaagcaaat ccaccagata atgaaactcg
    10741 atattgtgat aggaaacgcc gtccgcttca aaacgatttt caaccacaaa agctagctgc
    10801 ccagcttgag atttaacacc cagttcttcc ttcacttcac ggactaccgc gtcttccgtt
    10861 ttttcgttaa cttgaatcgc accgccgata atgtaatact tgcccttgtc tttggtgact
    10921 agaagcttgc gattttgaag aatcaaagct gtcgcccgaa caccaaaaac cgtattgtct
    10981 acttttgtcc gaaagtcttg ttgagtcatt cttgtccttt cccttaaacg acacaaaaac
    11041 agtcaaaact acaaagaagt gcaggacaaa aaagcctgca acatccatga gctttgacca
    11101 tcatttctat tgctgttatt attgtagcaa attgagaaaa tttgtcaatc taaatgtact
    11161 gacaaacttg tccatcgcgg taagcattgt caatcaaacc accacctaga cactcttcgc
    11221 catcgtaaaa gacaactgcc tgtcctggtg taatcgcgcg ttgtggttcc gcaaagatga
    11281 cctctgcctt gtctcctttg acatggacgg tcaccttaga gtcaggctga cggtaacgga
    11341 atttagccgt acattctagc gtaaactctt ctggcatttc acgagtaaag tggacttgac
    11401 tggcttctag gctagttgac atgagcgaat catggtagaa tccttgtcct acatagagaa
    11461 tattcttgct tagatctttt ccgacaacga accaaggggc attgtcaccg ccgtgttgcc
    11521 caccgatacc gagtccgcca cgctgaccga ttgtatagta cataagacct gcatgctcgc
    11581 ccatatcgcg accatccaca gtcatcatgc gaccaggctg agctggcagg tagttgctga
    11641 ggaagttttt aaagttcttt tctccgataa agcaaatccc tgtcgagtct ttcttcttag
    11701 cagtcgccag gcctgcttct tctgctagtc tgcgtacttc aggcttttcc aaatgtccca
    11761 aagggaacat ggttttttgg agttgttctt gcgaaagttg gctgaggaaa taggtctggt
    11821 ccttgccatt gtccacgcca cgaagcatgt gaacagtgcc gtcctcatca cgcgccactc
    11881 gagcataatg cccagtcgct acatagtctg cccccaaggt catggcatag tccaaaaagg
    11941 ccttgaactt gatttccttg ttgcacataa cgtccggatt tggcgtgcgc cctgcacggt
    12001 attccgctag gaaatactca aaaacgcggt cccagtactc tttttcaaaa ttgacagagt
    12061 agtagggaat gccaatctgg tctgccaccg caaccacatc cttgtaatct tcggtcgccg
    12121 tacaaacacc gttttcatct gtgtcatccc agttcttcat gaagataccg atcacatcgt
    12181 agccctgctc cttgagcaaa agagccgtca ccgacgaatc aacaccacca ctcatcccca
    12241 cgacaacacg tgttttagag ttatcactca tggtaagtct ccatctattc gtttattcac
    12301 gattgaaggt cgtgtgtgct tcacgattga aggtcgcttg agcagtattc attataacac
    12361 gcttggttag agaagacaag gaagagctta aaaattgttt tttaaaactt atagtcaata
    12421 tacagatcat gtgaatgacg tgagtatacc ctcttcttat cttcattcaa ataactataa
    12481 taaataaaac aacccatttt ctctaatcta tttttc
//
LOCUS       DAVMAH010000054        12503 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVMAH010000054 DAVMAH010000000
VERSION     DAVMAH010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12503
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.054"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            111..275
                     /locus_tag="VYO94_001682"
     CDS             111..275
                     /locus_tag="VYO94_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1760284.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            359..925
                     /gene="amaP"
                     /locus_tag="VYO94_001683"
     CDS             359..925
                     /gene="amaP"
                     /locus_tag="VYO94_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV1760285.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            937..1107
                     /locus_tag="VYO94_001684"
     CDS             937..1107
                     /locus_tag="VYO94_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV1760286.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1146..1754
                     /locus_tag="VYO94_001685"
     CDS             1146..1754
                     /locus_tag="VYO94_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1760287.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1785..1988
                     /locus_tag="VYO94_001686"
     CDS             1785..1988
                     /locus_tag="VYO94_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1760288.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2098..2376)
                     /locus_tag="VYO94_001687"
                     /pseudo
     CDS             complement(2098..2376)
                     /locus_tag="VYO94_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2574..2861
                     /locus_tag="VYO94_001688"
     CDS             2574..2861
                     /locus_tag="VYO94_001688"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1760289.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRRLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3139..3909)
                     /locus_tag="VYO94_001689"
     CDS             complement(3139..3909)
                     /locus_tag="VYO94_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV1760290.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3924..4772)
                     /locus_tag="VYO94_001690"
     CDS             complement(3924..4772)
                     /locus_tag="VYO94_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV1760291.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKATGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTASDGFIGTAHVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4769..6244)
                     /locus_tag="VYO94_001691"
     CDS             complement(4769..6244)
                     /locus_tag="VYO94_001691"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV1760292.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6567..7922)
                     /locus_tag="VYO94_001692"
     CDS             complement(6567..7922)
                     /locus_tag="VYO94_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1760293.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMAYKTEL
                     S"
     gene            complement(7932..8249)
                     /locus_tag="VYO94_001693"
     CDS             complement(7932..8249)
                     /locus_tag="VYO94_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1760294.1"
                     /translation="MNESNLESVMGLIMYGGEAKSNAMEAIQASKKGDFSKANRRLVD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8266..8583)
                     /locus_tag="VYO94_001694"
     CDS             complement(8266..8583)
                     /locus_tag="VYO94_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1760295.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEINVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8596..10281)
                     /locus_tag="VYO94_001695"
     CDS             complement(8596..10281)
                     /locus_tag="VYO94_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEV1760296.1"
                     /translation="MKNNKLIFSLFILFLLIFIHAKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINGNRADGYIGQVIDIEPNEDYLVSAFAKVDVS
                     GAEGYFTARWFDDNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGHGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGNWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRDKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(10286..11182)
                     /locus_tag="VYO94_001696"
     CDS             complement(10286..11182)
                     /locus_tag="VYO94_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV1760297.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(11185..12447)
                     /locus_tag="VYO94_001697"
     CDS             complement(11185..12447)
                     /locus_tag="VYO94_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1760298.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         4252 a         2526 c         1860 g         3865 t
ORIGIN      
        1 ttgatttttt gatattaaaa taaaaaagga gggtaggcag tgttgtgatc aattattgct
       61 ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa aagtagttct atgggaatca
      121 tcgcaaatgt attcgctggt ttagtcgggg catatgcagg acaatctctt ttaggtagtt
      181 ggggtccatc aatcgctgga atggctttgc tcccatctat tgtaggtgca gcgattgtga
      241 ttactgtagt gtcattcttt acaggtagaa agtaaacttt tcgccagtaa agttagcaaa
      301 ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt aaatcgaaag gattgtatat
      361 gtcaaaagca aagaaaatat gtttcattat tttctgtatt ttaatcttga caattttcct
      421 tcctgttttg atagattatc atcaagttag tgatctaggt attcatctac ttagctggag
      481 acagaactcc gtagttgaat tctatcttgc tagatatgtc ttttggggga cagtggttct
      541 atcaacttta gttttattat ccattttagt tgtgatgttt tatcctaaac gttacttgga
      601 aatccaactt gaaactaaaa acgatacatt aaaattaaag aattcggcaa tcgaaggttt
      661 tgttagaagt ttggtgagtg atcatagatt gatcaagaac ccaactgttc atgtaaattt
      721 acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt cttccttcag acaacatcgc
      781 tgacagatgc caaataattc aaaatgaaat aactaatgga ttgaagcagt tttttggtat
      841 tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac caaccaaaac ctcaaaacaa
      901 aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg aatggcttaa acaatatcga
      961 tatccaatta tcgctggtct cataggcgta tttctggctt gtttgattgt ctcctttggc
     1021 ttcttcaaaa caatatttgt attgatttta ggagcactgg gagttgcagc tggattatat
     1081 atcgaaaaaa actatataga taaataaaaa aataaaaatt actaatttaa ttaaaggagt
     1141 ttcatatgtc aaacgaaaaa aacacaaaca ctaacgtaga aaagaaagat gctactgttg
     1201 tagctcacga aatcaaaggg gaacttactt acgaagataa agttatccaa aaaatcattg
     1261 gtctttcact agaaaacgtt tcaggtcttt tgggaatcga tggtggtttc ttctcaaatc
     1321 ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg tgttaacgta gaagttggta
     1381 aaacacaagt tgcagttgac ttaaacgtta ttgttgagta ccaaaaaaat gttccagctt
     1441 tatattcaga aatcagagaa atcgtatctt cagaagttgc taaaatgact gacttggaaa
     1501 ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa agaacagcat gaagcagact
     1561 cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc aacaggagaa ttcacttcag
     1621 aacaattcga aaaagctaaa tctggtcttg gatctggttt ctcaactgtt caagaaaaag
     1681 ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg tgtagtatct cacgaaaaca
     1741 ctcgtgtaaa ctaagataaa ataaatataa caggagaaat tatcatgtca gtagaagaaa
     1801 aattaaatca agctaaaggt tctattaaag aaggtgttgg gaaagccatc ggtgatgaaa
     1861 aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa agtaaaagaa gttgccgaag
     1921 acgctaaaga cgctgtagaa ggtgctgtag aaggtgttaa aaacatgttg agtggcgacg
     1981 ataaataagg ttaaaagtta ctttatcttt ttggtaacat tagtcaaaag agtctgagtc
     2041 aagatgattc tcagaaaaca aaaagctaga gattcccaat tgcggaactc tagcttttta
     2101 attttgcctc tttctcttat tatatttcag caggttgttg gccatgagta tgaatcccat
     2161 gtcaattctc acttgacgct tacctctcag atgacatctc ttataaccca aacaaacctt
     2221 tatctgccca aagacagatt tcatatcaat cttacgttta gcgaaaattt gtctaccctt
     2281 ggaagataaa agtgcctgat attctttagt ttttaaacac tggtaacgtt cattcatata
     2341 cagtcccttt tgaggggctg attcaggttc ataatcgcag tcaacattga tttcaaggct
     2401 gtttgctttc tatctcccct ttttcatgat atattttcgt acaggtgctt caatagtttc
     2461 tatagtaaaa tgaaccaaaa atagtacacg ttgcggtata atgttcttgt ggcatattca
     2521 ttagattttc gtaaacagtt ctctcctatt tgtgagcgaa caagtatagt caattgattg
     2581 tcagtttgaa gaccaagagt cgtaaggcaa aggatatggc agaatccatc caagggtggc
     2641 tggcacaatt tctagtgaac ctctttaaat ctattacgtt tgactgtgga aaagagtttt
     2701 caaaatggaa agatatttcc aatcatcacg atagtgagag cttttttgcg aatctaggat
     2761 gttcaagaca gcggcgtctc aacgaacatt caaatagact tttaaggtgt catgacttgc
     2821 caaagcagac agatttcaac gaagtcagtc aagaatttta ggctggacaa aaactcaatt
     2881 tcaggagaaa atgaaataaa tattcccaca ataaaacgca tagtatcaaa gtttttccaa
     2941 cacctgatat tatgcatttt ttaattttaa agactttttc ccagcctcaa gaaatcacat
     3001 cccacctaaa tcctttggat accaaatacc tcatcaggta ttttctgagt tggtaagact
     3061 gtctagctta atttgacaaa tggagggcgt taaatccagt ttttacagga agtctattta
     3121 aatattttca cactgacctt acaaaatatg aaataaatta tataaagtca ttcccatgac
     3181 aaagaataac atccctttaa aacagtatct tacccaattt tcaggtaaga cttttgatac
     3241 aaccgtcccc aatacccctc cgcatataga agcaagaaaa ataactggaa caggtgctaa
     3301 atgatactga tttaaacctg taaccacaac aattgtagcc aaatgagaca gctgggaaaa
     3361 gaaaataatt gcaagagaat acatcgttgc ttcttttatc gaaatagaaa aaaacaccat
     3421 caataaagat acattgagcg gaccaccacc aatccctaaa aaactagaaa ttaagcccaa
     3481 tagaagacca caaatcatat agaatcctat cttatcaaat tgataagttt ttttaaaatc
     3541 tgttaaaaca aatgatacaa gtagcatcac aaatagtaaa atcatttgaa caatggatac
     3601 tagccgtact gataattgag ataacaaaac ttgaaaaata agatgaccta gaaatcctcc
     3661 taaaacagaa gaaaaggata ccgtaaaaat caatctccat tttatctctt tactttgtga
     3721 aaatcttttg attgttgaaa taatcgccat tataaaaaca gagaaactag aataaaaagc
     3781 aatatcactg accgaatggt acccaaaact atccataagt ggcttaatta taattccacc
     3841 acccatgcct gatatagaac ccaatccact agctattata atgattagaa aataaataat
     3901 ctcaaccact ttttaagtcc atcctattct ttcaaacatc taaaacctag atggctacta
     3961 gtggaagtag aaatacatcc atttctagca gctactcggt atcgattaca ataagaacaa
     4021 tgacataaaa aggaacctcc tctgatagca tactcctcat cttgtatccc atattttggc
     4081 aactcatagt catcttcatt aaaactagct aataaggtat atctcggatt gcgacaccat
     4141 tcccaaacat tcccaatcat ttgatataga ccaaaatcat taggtaaaaa ttcatagaca
     4201 tgagccgttc ctataaatcc atctgaggca gtattttcat aaggaaatct tccttgccaa
     4261 gtattggcat gataatatcc accttctaaa agagtatctc cccaaggata ttcagattgt
     4321 cttcctcctc tagcagcata ttcccactgt gcttcagtcg gtaaagacat tccgctccaa
     4381 ttacagaaag ccaatgcatc ttctaaagca acatgaacta ctggatggtc ttctaaaccc
     4441 actagattac tattctcacc gtagggatgc ttccagcaag cgttcggaac ttgtaaccac
     4501 cacggagccc cagcaggatg aggatatccc tccctttctg cctctggaac gaacaatata
     4561 aaaacaaaag accactcttg tcgctcagct agtgttttat agcctgttgc tttcacaaat
     4621 tgagcaaatt cttgattcgt aactggagta tccgcaatgg aaaaatcctt tacactaaca
     4681 gcgacttgag gaccttcaaa atcatctaaa aagccctctt cagaatttgt tcccatcata
     4741 aatgtcccac ccttgatttt tttcattttc atgattgact atcccccgtt ttcgttagag
     4801 ttggcgttat tttagaaagt tcaacaggaa ctaactcttc atccacaaca aaaccttctt
     4861 ctctatatct aagaaagtct actaattttt tcttcatctg acgaacaata ggttggtatt
     4921 tttcacttgg atacaaatca ttcatttcat gcggatcttt tttcatatca aataactgat
     4981 aatgatttaa aacaggaaac cagataaatt tccactggtc tgtcaagata tattgactag
     5041 aatcttttcc taaagcatgt tcaccatgaa attctgttcg ccacccctcg tactgtccaa
     5101 ataataaatt cttaacactc cgtccatcta gttcatctgt agtagttcct cctgccaaat
     5161 ccacgagtga aggaaaaata tcttgaattt tcactaattg cttgattgtt cccctattac
     5221 cagctatcaa tccagccgga tcgtaaataa acgaaggaat gtggatactt ccctgataag
     5281 gatatccctt tctaaacaga taatgttcac caagctgatc tccatgatcc gaaacaaacc
     5341 agataatcgt atctttatca tgacgaaatt cttttagggc agtcaaaaag cgactaattt
     5401 gatggtctat atgagtaatc aatccaaaat aagcagcaac cattcttctt tgatcatctt
     5461 cctttaattt ccctcttaaa gcataaatag acggaatttg cttttctaat acttcccaat
     5521 tcccgatatg caaatcgaga aattgaggca agcgttccat atacatatca aaatagtatt
     5581 ttgggggatt taatggagca tgtggttttt caaaagacat tttgagaaaa aaaggaaccg
     5641 ttggatctct tctttgtaaa aatgaaatgg actcactcac aacccagttt gttggatgta
     5701 acttctcatc tttatcccaa ggtctagctt cccaagaatt acaatccatt ccgtcatcaa
     5761 tcaaatcaac atcataacca actttaccct ttaaaaaggc tagatagtca ctagcataat
     5821 caaattgact tccataagcc ttatcatact ttctatcaac atgtagatac ccatcgtgaa
     5881 gtaagacatg atcaaaccca agtctctgtc tggaaggaaa aacatgcatc ttaccaatac
     5941 actctgtttg ataacccata tctttaaaga cttttggaag agtattagta aaattccaag
     6001 gcacctcatc ttgataacca actcgtccac ttttatcttg gtctaagcca gtcaataaag
     6061 ctgccctagc aggaacgcaa gaaggaactg gagaataggc attttcaaaa ttataaccta
     6121 cactagccat catatctaat gttggagtgc taactagctt atccttacta ttcaaggata
     6181 aggcgtctgc tctcatttga tctacaacaa tcaaaataat atttggctgt tttgtctgaa
     6241 ccataaaatc tcctttctaa tatggcaaaa gaggcacaag aagatatcta cctttactgc
     6301 acccctttct atatcaatct ctctatataa aacaataaca ttcttgttat gttttataga
     6361 aaaatgaact aaaatatgac taaatcgatt aggaaattca aatcattttc tagtactgtt
     6421 ttagaagtta cagtgtacta ttccaacttc aataaactat aaacctttgt ctaataacaa
     6481 ttttagtgga gataagaaat cctacaccta actcatctta cacgtaatct atttctattt
     6541 tatcacaaaa aacgcaagta agaccattaa ctcaattcag ttttatatgc cattttcaca
     6601 aatgggaaat aagtcaagac actaataatc aaacaaacaa ctgataagat gatggcacgc
     6661 caatcaaatg ctgtagagaa gaaaccatat aaaattggag gcattaccca agtaacattt
     6721 tgtgtaacag gtgaaacaag accccagctt gttgcccagt aagctaccgt tgccatgaaa
     6781 accgggctaa gtacaaatgg tataaatagc aaaggattca agacaactgg taaaccataa
     6841 ttgaccggct caccaatatt aaacagaact ggtgctagac caagtttagc aacttttcga
     6901 taatgactgt ttcttgaaaa aattaaaata gcaagtacta atcctaatcc tccaaaccag
     6961 acaaacgccc caaaagaccc acttgtccat atataaggaa tcggttcacc tttttggaaa
     7021 gcatccagat tcgctaacat agcaactcca aatagccctt ccatgatggg agccaataca
     7081 tttcctccat ggagaccaaa aaaccagaat aacttattca aaaagatcat cagaataact
     7141 gcaaagaaac tttgagacaa acctagtaat ggcgtttgta acaccttgta aacccaatca
     7201 atcaataagt cattgctaag taaatggaaa acataagtca agatggctac tatatacatc
     7261 gccataaatc ctggaatgat agaagtgaac ggcttagcaa tcgcaggggg aactgaatct
     7321 ggtaacttga ttacccagtt ctttttcatt actttacaga aaataataga ggctaaaaat
     7381 ccaatcatca tggctgtaaa gtagcctctg gcattaatat ggtttcctgg aatcacattc
     7441 ccaatagtta ccatcagatt tttaccatca aatgctagat tatcaattcc ttgtaagatt
     7501 tgatctaatt tcacatctcc tacatttgcc aaagggaaac tctttgtaac tgtacttcca
     7561 atcgaaatga caaacgaagc aagcgatacc aaaccagcag aaactgtatc aaccttgtaa
     7621 atcttagcga tattcactcc caagcaatag atgaacaata aggaaacaat tggtatactt
     7681 cccttgaata ccaaattatt gatgtcaaca agccactgaa aggttttcgt aatactttct
     7741 aggtgaaatt gttgtggtaa atccactaga aaagcattta ataacaaagc aatggaacct
     7801 gtcataataa caggcatagt tcccacaaat gaatcacgta aagcaactaa aaacttctga
     7861 ttcccaactt tcattgcaat tggagaaagt ttttcttgca ttttatccaa cattgtattc
     7921 ataccaaact cctaattttt ttcaaatcgt tcgtatactt ctaccacttc tttcgccaag
     7981 tcaacaaaag tcagactcgt cattaaatga tcttgcgcgt gtaccatcaa gaggctaatt
     8041 gatgtttctt ccccctgtgc ctcttttgtc aacatttctg tttgagcctt atgcgcctgt
     8101 aataaggcag catttgcatc aactaatctt cgattggctt tagaaaaatc cccttttttt
     8161 gatgcctgaa tagcctccat agcattactt ttggcttccc caccatacat aattagcccc
     8221 attacagatt ctaaattact ttcattcata gcattctcct caatcttagt ctaataaact
     8281 ttcagctaaa tctaagactt tagaaccatt catcattccg taatctgtca tcggaataac
     8341 cgccacagga atctgtctat cttttagttt ttcttgaaag tcccctagta aatagcgaac
     8401 ttgaggacct aaaagcaaca catttatttc ttttgttgct acaatttctt ctgcttcagg
     8461 agctggaact gcaaaaattt ctgcatccaa ccccttatct tctgctgcct tttgcatctt
     8521 tgtcactagc agacttgtac tcatacctgc tgcacacgct aacataattg ttactttagc
     8581 catagcttac tccttttatt ttattgtcaa tgttactgtt tttcgatcaa ctttagactc
     8641 ataatctaaa tgtttgggac gactagtata atgcaaatta taaactcctg gaggcatttg
     8701 tgaaatcttt tccttttcag ttttatctct aattaataaa tctaccgaag tattccctcc
     8761 aaagttatta aacataggtt cattctcaat agaataatct agctcatatc cactattagt
     8821 tgtaattcct tttaataaat caggaacatc tcctctgttt attactatat ctttagcgcc
     8881 atttatttta ggagattgac tataatactc ttcagcttga tgttgttgta aatcatttct
     8941 agagtaagaa acataatcaa ctacaaattc tgttcctgat aaattattgt ccactactcc
     9001 gggccaattt cctcccatcg ctaaatttaa ctgaacatac tgaggtctat taaaaatctt
     9061 tttcgctata ttatctgatc cataatatac ttttctgaca atatgattgt caaccatcca
     9121 tacaatataa tctttatacc aatcaattga aaaagtgtga tacgaatcat taaagtttcc
     9181 actcgataat ttaaaggctg taccatgtcc tgcaaatttt ccatcatcat tatccgactg
     9241 tccataatga agcgtttgat aaactgtctt attcccactt ccatttgaat ttcgttcacc
     9301 aactaattcc attatatcta tctcacctgt tgacggccat cctcgtccct gaacaggatt
     9361 aatcttccca tcaagtgtaa aatccgatcc aagagtccag aaagcaggaa aaactccttg
     9421 acctttcggt aattttgcac gcatctctaa tttaccataa agaaattcta ctttcccatg
     9481 tgttctaaca cttcctgaat tatatacaac ctttctgtga ttgtttcttg ggttaaaata
     9541 ctgatcttcc ttagagcgat tcgtagctct aagaactaaa tttcccgaac gtagaaaaac
     9601 attctcatca cttcttacat aatgttgctg ttcccaacca cgaattgatc ctaattcata
     9661 tccccaatat tttttattta attgttcgcc atcaaaatca tctctccaaa ttttcttata
     9721 tgaatttcct ttagacagtt gatacatctc tacattatca ataaaaatat tagatttttt
     9781 tgtagtatcg tcttctgacc atttcactaa ttgaatcaaa actttatcgt gtttaccgga
     9841 attgaaagaa aacatgtatt ttttccattc ggttgtatta actgtttgat caacagcttc
     9901 tccaatgtta ttttgaacaa tctctccttg cttattatca tcaaaccatc ttgcggtaaa
     9961 atatccctct gctccactaa catctacttt ggcaaaagca gatactaaat aatcttcatt
    10021 aggttctata tcaataactt gtccaatata tccatctgct ctattaccat taattgcagt
    10081 agaaggaatc atacctgagt aatgtccgtt actataactc tcatttgaat taattattcc
    10141 cctatttcta gagttccaaa acagctctcc ttgctcaaaa tttgaatttt ttattaaatt
    10201 ttcattagca aaaactttcg catgaataaa tattaataaa aataatataa ataaactgaa
    10261 aattaattta ttattcttca ttttatcacc tatttactga cctagccaag cgagatactg
    10321 tatgtctcac tcctctaatt gccttgctca atgcataaat attatcgact gttgccagtc
    10381 ccccatatcc tgcgtcacct atatgttgaa tatcaactcc acaaatttta tttctaagtg
    10441 caatttcctt gatagtatct gtatcagatg tttcttggct agtaccgata gcactcaata
    10501 caagaccacc cttactatga acgagatcaa cgacttcacg caactcttgg tcatgaaagg
    10561 ctggaacggt tccaactgct ggaacaagta tcacatccgc acctgcttcc aacaattgct
    10621 ctgcgacaga aagctctgcc acaggctcat tcactcctgc cccgtgcatc ttacctgcaa
    10681 taatcaaacc agaaaagttt tccttagcag tttgaacagc cttaatgatt tctcgattgc
    10741 taactcctgt tccaggattt ccagtcaaac agacaaagtc aaaacctaac tcctctattc
    10801 gcttcaatgt ttcaacacta gcaacacgac ctgcaacaat ttcctgtgtt tcctctagca
    10861 tctttgcaga tgggtcaatc ggttccaaat ttacaccaat tggacaagca acaagctggt
    10921 gtaagcgatg aataacatca tcacctgaac tatccaaagc ataaatttta ggctcaaaaa
    10981 catcaacaca attcaataaa atcatatcag ctccaaaagc tctagcaatt tcagaattag
    11041 ttatatcccc aacaaatgtc tcacgagtaa ctacattttc agatagaaca actctacctt
    11101 cacttgctaa aatactttgt tttaattctt cagcattcat ctgtaatatc tcagatggat
    11161 ttgcactaat taaacgtttc attctcaatc ctccaataac ttaaaccgtt tttcaatagc
    11221 tattacaaat ggtaaataaa gtaagacatc caaaacaatc aatacaattt gtaataatga
    11281 accagaaata cttcctgtag caagtaaacc acttataaca ggtggcatag tccaacctgg
    11341 atctgtataa gttagcggaa ccaaacctga tgccattgct ccccacgcta ctagtaagtt
    11401 aaacattgga gctaagataa atggaactag taacaaaatg ttcaaaacaa taggaacgcc
    11461 aaacattgct ggttcattta tattaaataa tccaggtata acagttatag gtgccaaagt
    11521 ttttagttgt ttactagctt tcttcttatg tgctaaatat cctaacgcaa gaactaaacc
    11581 tatggttgca ccaccgccac ctatgaatac aaaattatcc ataaatacgc tagtaaaaat
    11641 atttggaaga gtttctccag tttgataagc tactttattt gcatctagat tagctaacca
    11701 taacggtttc ataactgcat taacaacatt tcctccgtgt aatcctacaa accaaaaact
    11761 actattaagg aaaattaaga taagaagacc aataacatta tttcctaaaa gtccaagtgg
    11821 acctcccaaa gctacttgag caatttcatg aagattaggt aaacttaatt tatctaaagt
    11881 tgcataaaca atcaaccaac caacaatagt cactgcacca ggaataatgg cactaaagct
    11941 tttagatact gctggtggaa caccatccgg catttttatc tgtatattat gatttataaa
    12001 ccattggtag atatagccat taatcaatcc taaaatcata gcaacaaata aaccttttga
    12061 tgccatgaaa gcggtaggca ttcctgctcc agcctctcct gtaatgaaag gcgtaactgt
    12121 aataaaagat gataatgaca caataccagc aggaatacca tcaactttgt attgtctagc
    12181 cataaagtaa gcgataccaa aactagctac aagaccaagt aatccaaaac tactatcaac
    12241 acccttccat aaatagtcag caacaccaat atcacccaga tatttttccc atcctggaat
    12301 aggaaaactt gcaataacca ttagtaatga acctatcaac aataaaggta tagttagagt
    12361 aataccgtct cgaatagaaa ccaacgcttt attattaccc aatctagccg ctactggaag
    12421 taacttttct tgtaataatt tttccataac cttttcctct taaatatatt ttattatcaa
    12481 aagttatcaa ttatctttat ttt
//
LOCUS       DAVMAH010000055        11840 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVMAH010000055 DAVMAH010000000
VERSION     DAVMAH010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11840
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.055"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(34..870)
                     /locus_tag="VYO94_001698"
     CDS             complement(34..870)
                     /locus_tag="VYO94_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1760299.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            996..3191
                     /locus_tag="VYO94_001699"
     CDS             996..3191
                     /locus_tag="VYO94_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1760300.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            complement(3422..4879)
                     /locus_tag="VYO94_001700"
     CDS             complement(3422..4879)
                     /locus_tag="VYO94_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEV1760301.1"
                     /translation="MKRIQLNMNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRL
                     LLAYQQKGKEAFRHGHGNRNRKPKHAIPDEIKERVLKKYLSYETYKPNVLHFCELLAE
                     EEGIKLSDTTVRKILYKKNILSPKSHRKTKKRVRKQAKLNLNQPLDNPILPTAKDFLE
                     DPKKVHPSRPRKKFAGELIQMDASPHAWFGPETTNLHLAIDDASGNILGAYFDKQETL
                     NAYYHVLEQILANHGIPLQMKTDKRTVFTYQASNSKKMEDDTYTQFGYACHQLGILLE
                     TTSIPQAKGRVERLNQTLQSRLPIELERNKIHTLEEANTFLLSYIQTFNEQFGNKTKL
                     SVFEEAPNPSERNLILARLAERVVDSGHHIRFQNRCYIPTEQGKEVYFIRKTKALVLK
                     AFDGDIYLNIADKIYHTKELLDHELYSKNFEQEPEQKKKDASISLHKPIRGNSHLSNN
                     TFIKTKRIMKSLLARRFILLNYKYNLFFAKWEAFP"
     gene            5022..5174
                     /gene="rpmG"
                     /locus_tag="VYO94_001701"
     CDS             5022..5174
                     /gene="rpmG"
                     /locus_tag="VYO94_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1760302.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5184..5360
                     /gene="secE"
                     /locus_tag="VYO94_001702"
     CDS             5184..5360
                     /gene="secE"
                     /locus_tag="VYO94_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV1760303.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            5415..5951
                     /gene="nusG"
                     /locus_tag="VYO94_001703"
     CDS             5415..5951
                     /gene="nusG"
                     /locus_tag="VYO94_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV1760304.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            6073..6552
                     /locus_tag="VYO94_001704"
     CDS             6073..6552
                     /locus_tag="VYO94_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1760305.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGELSHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            6646..6717
                     /locus_tag="VYO94_001705"
     tRNA            6646..6717
                     /locus_tag="VYO94_001705"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6679..6681,aa:Glu,seq:ttc)
     gene            6970..8515
                     /locus_tag="VYO94_001706"
     rRNA            6970..8515
                     /locus_tag="VYO94_001706"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            8567..8639
                     /locus_tag="VYO94_001707"
     tRNA            8567..8639
                     /locus_tag="VYO94_001707"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8600..8602,aa:Ala,seq:tgc)
     gene            8764..11665
                     /locus_tag="VYO94_001708"
     rRNA            8764..11665
                     /locus_tag="VYO94_001708"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            11742..>11840
                     /gene="rrf"
                     /locus_tag="VYO94_001709"
     rRNA            11742..>11840
                     /gene="rrf"
                     /locus_tag="VYO94_001709"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         3467 a         2183 c         2990 g         3200 t
ORIGIN      
        1 aaatattata gagccgaaaa atggatgaca cgatcatcca ttctttttta attctttttc
       61 aaatgtattt gaaagggtag tgaaagttag cttctctaaa gtaagtgggt gggtaaagga
      121 aagtcggaag gcatgaagca taagccgact tgtctttgat ttactattat agagagggtc
      181 gcccaggata ggaagattat gatgcgaaag gtgcacacga atctgatggg ttcgccctgt
      241 ctttagcttg caacgagcca aggaagtctt gtttgagaat tgctttaatc tgcttacata
      301 cgtttcagca tattgcccat tttttgcatc aactattctt tttctacgat catggcgatc
      361 acgtccaatt ttgtctctga aaacaagttc ttttctgttg atatttccat caactagagc
      421 ccaatattct ctagaaatct cttttttctc caataagcga ttgagaatgg gcaggataaa
      481 aggatttttg gcaaagagaa ctaagccact ggtttccatg tccagacgat gaacgacata
      541 gcaggtttgg ccaacatagg tactgacatg gttaagaaga gcaatttcgt ttggttgatt
      601 accatgcgtt ttcatcccct ctggtttgtt tacaataatc aagtgttgat cttgataaac
      661 ttcctgcact aagtctgggt tgccccaagg gatcgtcttt tgggaataat cttcctcgtc
      721 aaaagtcaac tggcaaacat ctccaggatt tacgatttcg ttccagtgga cttcttcttg
      781 atttatcaaa atatgtttct tgattctcaa aaaatgacgg atttttctag ggatgaggag
      841 ttgttcctca agtaattgct ttaccgtcat ttgaggtaga gaggcgggta atgtaaatgt
      901 gaattgcata cagatattgt aacaaaaaaa gccctatttg gataggaaat agctaaattc
      961 ttgtcttcct atgatgaaga tgataaaata aacgcatgaa attagataaa ttatttgaga
     1021 aatttctttc tctttttaaa aaagaaacaa gtgaactaga ggactctgat tctactatct
     1081 tacgtcgctc tcgtagtgat cgaaaaaaat tagcccaagt aggtccgatt cgaaaattct
     1141 ggcgtcgtta tcatctaaca aagattatcc ttatactagg tttgagtgca ggattgctag
     1201 ttggaatcta tttgtttgct gtagccaagt cgaccaatgt caatgatttg caaaatgcct
     1261 tgaaaactcg gactcttatt tttgaccgtg aagaaaaaga ggctggtgcc ttgtctggtc
     1321 aaaagggaac ctatgttgag ctgactgaca tcagtaaaaa cttgcagaat gctgttattg
     1381 cgacagaaga ccgttctttc tataaaaatg acgggattaa ctatggccgt ttcttcttgg
     1441 ctattgtcac tgctggacgt tcaggtggtg gctctaccat tacccaacag ctggctaaaa
     1501 acgcctattt atcgcaggat caaactgttg agagaaaagc gaaagaattt ttccttgcct
     1561 tagaattaag caaaaaatat agtaaggagc aaattctaac catgtacctt aacaacgctt
     1621 attttggaaa tggtgtgtgg ggtgtagaag atgcgagtaa gaaatacttt ggagtttctg
     1681 catcagaagt gagtctggat caagctgcga ctctggcagg gatgctcaag gggccggaac
     1741 tgtataatcc cttgaattcc gtagaagatt ctactaatcg gcgcgatact gtcttgcaga
     1801 atatggttgc agcaggatat attgataaaa accaagaaac cgaagctgct gaagttgata
     1861 tgacttcgca attgcacgat aagtatgaag gaaaaatctc agattaccgt tacccctctt
     1921 attttgatgc ggtggttaat gaagctgttt ccaagtataa tctaacagag gaagagattg
     1981 tcaataatgg ctaccgcatt tacacagagc tggaccaaaa ctaccaagca aatatgcaga
     2041 ttgtttatga aaacacatcg ctatttccga gggcagagga tggaacgttt gctcaatcag
     2101 gaagtgtagc tctcgaaccg aaaacagggg gagttcgtgg agttgtcggt caagttgctg
     2161 acaatgataa aactggattc cggaatttca actatgcaac ccaatcaaag cgtagtcctg
     2221 gttctacaat taagccttta gttgtttata cgccagcagt tgaagcaggc tgggctttga
     2281 ataagcagtt ggataaccat accatgcagt atgacagcta taaggttgat aactatgcag
     2341 ggatcaaaac gagtcgagaa gttcctatgt atcaagcctt ggcagaatcg cttaatctac
     2401 ctgctgttgc cactgttaat gatttgggtg tcgataaggc ttttgaggca ggcgaaaaat
     2461 tcggactcaa catggaaaag gtcgaccgtg ttcttggtgt cgccttggga agcggtgttg
     2521 aaaccaaccc tcttcaaatg gctcaagcat acgctgcctt tgcaaatgaa ggtttaatgc
     2581 ctgaagctca ttttattagt agaattgaaa atgctagtgg acaagttatt gcgagtcata
     2641 aaaattcaca aaaacgggtg attgataagt ctgtagctga caagatgacc agtatgatgt
     2701 tggggacttt caccaacggt accggtatta gttcatcgcc tgcagactat attatggcag
     2761 ggaaaactgg aacaactgaa gcagttttca atccggagta cacaagtgac cagtgggtaa
     2821 ttggttatac tccggatgta gtgattagcc actggcttgg ctttccgacc actgatgaaa
     2881 atcactatct agctggctct acttcaaacg gtgcagctca tgtctttaga aacattgcca
     2941 ataccatttt accttatacg ccaggaagta cctttacggt tgaaaatgct tataagcaaa
     3001 atggaattgc accagccaat acaaaaagac aagtacaaac caatgataat agccagacag
     3061 atgataattt gtctgatatt cgagggcgtg cgcaaagtct agtagatgag gctagccggg
     3121 ctatctcaga tgcgaagatt aaggaaaagg ctcaaacaat atgggattcg atagtcaatc
     3181 tatttcgcta agatgctgtc aatcgaaagt gattatgtcc ccaaaaaatg gagagtttga
     3241 gggcaattat tttgatttca tttgacacga ggagcccttg aagctgtttt gttagctaaa
     3301 ccaaggctag tcttagcctt ggctcgccag cctaacagct ccaagcctct tatcaaatga
     3361 aatgcttgtc ttacactcct cactttccct ctcctaaatg taagggatag agtggttttc
     3421 tttaaggaaa agcttcccat ttagcgaaaa atagattata cttgtagttg aggagaatga
     3481 atctcctcgc tagtaaactc ttcataatcc tttttgtttt tatgaaggta ttgtttgaaa
     3541 gatgtgagtt tccacggatg ggtttgtgga gggatatact tgcgtctttc tttttttgtt
     3601 ctggttcttg ttcaaagttt ttcgaataga gttcatgatc tagtagctcc tttgtgtgat
     3661 agattttgtc agcgatattg aggtagatgt caccatcaaa tgcttttaga actaatgctt
     3721 tcgtctttct gatgaaatag acttcttttc cttgttcggt aggaatatag caacggtttt
     3781 ggaatcggat atggtgtcca ctatcgacga ctctctccgc cagtctagct agaatgagat
     3841 tccgttcaga ggggttagga gcctcctcaa aaacagagag ttttgtctta tttccaaact
     3901 gttcattaaa ggtttggatg taggaaagaa ggaaagtatt ggcttcttcc aatgtatgaa
     3961 tcttgtttcg ttccagttcg ataggcaggc gtgattgtag tgtctgattg agtctttcga
     4021 ccctcccttt agcttgaggg atagaggtgg tctcaaggag aatccctagt tggtgacagg
     4081 cgtatccaaa ttgtgtatag gtgtcgtcct ccattttctt agagttggat gcttgatagg
     4141 taaagaccgt tctcttatca gttttcattt gaaggggaat gccgtgattg gctaagattt
     4201 gttcgaggac atggtagtag gcattcaagg tctcttgttt gtcaaaataa gcccctagga
     4261 tattgccgga agcatcatca atggctaagt gtaagttggt ggtttctggt ccaaaccagg
     4321 catgagggct ggcatccatt tgaatgagtt ctccagcaaa tttctttctg ggtctactag
     4381 gatgtacctt tttagggtct tccaggaagt ctttagccgt cggtaagatt ggattgtcta
     4441 ggggttgatt caggttcagt ttagcttgtt ttcttactct cttctttgtc tttctgtgag
     4501 acttaggaga aaggatgttt ttcttataga gtatttttct aacagttgta tcagagagct
     4561 taattccctc ttcttcagct agtaattcac agaaatgaag gacatttggt ttatatgttt
     4621 cataggagag gtatttcttt aggacacgtt ctttgatttc atcagggatt gcatgttttg
     4681 gttttcgatt tctgtttccg tgtccgtgtc tgaaggcttc ttttcctttc tgttgatagg
     4741 ctagtaacag acgattgatt tgtctttcag aaagattgag ttcgacacag gcccgtttct
     4801 ttgttttctt tccttgggct atagctttta tcacaagata ttttttcgtt tcattcatat
     4861 tcagttggat ccttttcata tgactattct accaaatggg acattttcac gttcgattta
     4921 ctaaagacat tatcacattc gaatcacaat agtcaatcta tttcgctaag atgcttgtca
     4981 aagcctagct ttcttgttat aatggataag atggaggcgt tatggcacta aaaaaagcaa
     5041 gcctagcttg tgcggtttgt ggttcgagaa actattcaat caagatcagc ggaaacccca
     5101 agcctacacg actagaagta aataaatttt gtaagcattg tggcaagtac actacacaca
     5161 gagaaacgag ataggagaga gcgatgcgtt ttattggaga tatttttaga cttcttaaag
     5221 acacaacgtg gccaactcgc aaggaaagct ggagagattt tcgttctatc atggaataca
     5281 cagctttctt tgtagtaatt atttacattt ttgaccagtt gattgtttca ggtttgattc
     5341 gatttattaa cattttttag aagattagtg gagttaatta cactagaaat cttctattta
     5401 tgaaaggaaa tatcatggat agttttgata aagggtggtt tgttttacaa acttattctg
     5461 gttatgaaaa taaggtgaaa gaaaatctat tacaacgtgc acaaacctac aatatgttgg
     5521 ataatattct acgcgttgaa attccaacac aaacagtgca agttgaaaaa aatggaaaga
     5581 gaaaagaagt agaagaaaat cgctttccag gttatgttct tgtagaaatg gtcatgacag
     5641 atgaagcttg gtttgttgtt cgaaacacac caaatgttac aggatttgtc ggatcacacg
     5701 ggaacagatc aaaaccaact ccattattgg aacaagaaat tcgtgacatt ttggtatcta
     5761 tgggacaaac tgttcaagaa tttgatttcg atgttgagat tggtcaaact gtacgtatta
     5821 ttgatggtgc ttttgcagac tacactggta agattacaga aattgataat aacaaagtga
     5881 aaatgattat ctctatgttt ggtaatgaca cagttgcaga agtaaaccta aaccaaatcg
     5941 cagaattata accctgagag aggctggagc ctctcttttt tgtgcagttt aggagctaaa
     6001 gggaacagaa tggagaaaat ggaacaaatg tgttttctaa tctgttagac tgtatctaga
     6061 aaggggaaaa ttatgattaa agaattgtat gaagaagtcc aagggactgt gtataagtgt
     6121 agaaatgaat attaccttca tttatgggaa ttgtcggatt gggaccaaga aggcatgctc
     6181 tgcttacatg aattgattag tagagaagaa ggactggcag acgatattcc acgtttaagg
     6241 aaatatttca aaaccaagtt tcgaaatcga attttagact atatccgtaa gcaggaaagt
     6301 cagaagcgta gatacgataa agaaccctat gaagaagtgg gtgagctcag tcatcgtata
     6361 agtgagggag gtctctggct agatgattat tatctctttc atgaaacact aagagattat
     6421 agaaacaaac aaagtaaaga gaaacaagaa gaactagaac gcgtcttaag caatgaacga
     6481 tttcgagggc gtcaaagagt attaagagac ttacgcattg tgtttaagga gtttactatc
     6541 cgtacccact aggaagtcat gcaaaaaaaa tgaaaaaaat tagaaaaagt agttgacaaa
     6601 gtttgaaaag actgtataat agtaagagtt gaaaataaca actcaggtcc gttggtcaag
     6661 gggttaagac accgcctttt cacggcggta acacgggttc gaatcccgta cggactatgg
     6721 tatgttgcgt caggaccact tgatgaaaaa aagtttaaaa aagcttaaaa atcttcaaaa
     6781 aagtgttgac aagtgaaagt ggctgtgata tactaatata gttgtcgctt gagagaagca
     6841 agtgacaaag acctttgaaa actgaacaag acgaaccaat gtgcagggcg ctacaacata
     6901 agttgtagta ctgaacaatg aaaaaaacaa taaatctgtc agtgacagaa atgagtgaga
     6961 actcaaactt ttaatgagag tttgatcctg gctcaggacg aacgctggcg gcgtgcctaa
     7021 tacatgcaag tagaacgctg aaggaggagc ttgcttctct ggatgagttg cgaacgggtg
     7081 agtaacgcgt aggtaacctg cctggtagcg ggggataact attggaaacg atagctaata
     7141 ccgcataaga gtagatgttg catgacattt gcttaaaagg tgcacttgca tcactaccag
     7201 atggacctgc gttgtattag ctagttggtg gggtaacggc tcaccaaggc gacgatacat
     7261 agccgacctg agagggtgat cggccacact gggactgaga cacggcccag actcctacgg
     7321 gaggcagcag tagggaatct tcggcaatgg acggaagtct gaccgagcaa cgccgcgtga
     7381 gtgaagaagg ttttcggatc gtaaagctct gttgtaagag aagaacgagt gtgagagtgg
     7441 aaagttcaca ctgtgacggt atcttaccag aaagggacgg ctaactacgt gccagcagcc
     7501 gcggtaatac gtaggtcccg agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc
     7561 ggttagataa gtctgaagtt aaaggctgtg gcttaaccat agtaggcttt ggaaactgtt
     7621 taacttgagt gcaagagggg agagtggaat tccatgtgta gcggtgaaat gcgtagatat
     7681 atggaggaac accggtggcg aaagcggctc tctggcttgt aactgacgct gaggctcgaa
     7741 agcgtgggga gcaaacagga ttagataccc tggtagtcca cgctgtaaac gatgagtgct
     7801 aggtgttaga ccctttccgg ggtttagtgc cgtagctaac gcattaagca ctccgcctgg
     7861 ggagtacgac cgcaaggttg aaactcaaag gaattgacgg gggcccgcac aagcggtgga
     7921 gcatgtggtt taattcgaag caacgcgaag aaccttacca ggtcttgaca tccctctgac
     7981 cgctctagag atagagtttt ccttcgggac agaggtgaca ggtggtgcat ggttgtcgtc
     8041 agctcgtgtc gtgagatgtt gggttaagtc ccgcaacgag cgcaacccct attgttagtt
     8101 gccatcattc agttgggcac tctagcgaga ctgccggtaa taaaccggag gaaggtgggg
     8161 atgacgtcaa atcatcatgc cccttatgac ctgggctaca cacgtgctac aatggctggt
     8221 acaacgagtc gcaagccggt gacggcaagc taatctctta aagccagtct cagttcggat
     8281 tgtaggctgc aactcgccta catgaagtcg gaatcgctag taatcgcgga tcagcacgcc
     8341 gcggtgaata cgttcccggg ccttgtacac accgcccgtc acaccacgag agtttgtaac
     8401 acccgaagtc ggtgaggtaa ccgtaaggag ccagccgcct aaggtgggat agatgattgg
     8461 ggtgaagtcg taacaaggta gccgtatcgg aaggtgcggc tggatcacct cctttctaag
     8521 gataaggaac tgcgcattgg tcttgtttag tcttgagagg tcttgtgggg ccttagctca
     8581 gctgggagag cgcctgcttt gcacgcagga ggtcagcggt tcgatcccgc taggctccat
     8641 tggtgagaga tcaccaagta atgcacattg aaaattgaat atctatatca aatagtaaca
     8701 agaaaataaa ccgaaaacgc tgtagtatta ataagagttt atgactgaaa ggtcagaaaa
     8761 taaggttaag ttaataaggg cgcacggtgg atgccttggc actaggagcc gacgaaggac
     8821 gtgacaaacg acgatatgcc ttgggtagct gtaagtaagc gatgatccag ggatttccga
     8881 atgggggaac ccaacaggta gtacctgtta cccacatctg ttaaggatgt gaggaggaag
     8941 acgcagtgaa ctgaaacatc taagtagctg caggaagaga aagcaaaagc gattgcctta
     9001 gtagcggcga gcgaaacggc agaagggcaa accgaagagt ttactcttcg gggttgtagg
     9061 actgcaatgt ggactcaaag attatagaag aatgatttgg gaagatcagc caaagagagt
     9121 aatagcctcg tatttaaaat agtctttgta cctagcagta tcctgagtac ggcgggacac
     9181 gtgaaatccc gtcggaatct gggaggacca tctcccaacc ctaaatactc cctagtgacc
     9241 gatagtgaac cagtaccgtg agggaaaggt gaaaagcacc ccgggagggg agtgaaatag
     9301 aacctgaaac cgtgtgccta caacaagttc gagcccgtta atgggtgaga gcgtgccttt
     9361 tgtagaatga accggcgagt tacgttatga tgcgaggtta agttgaagag acggagccgt
     9421 agggaaaccg agtctgaata gggcgcctta gtatcatgac gtagacccga aaccatgtga
     9481 cctacccatg agcaggttga aggtgcggta agacgcactg gaggaccgaa ccagggcacg
     9541 ttgaaaagtg cttggatgac ttgtgggtag cggagaaatt ccaaacgaac ttggagatag
     9601 ctggttctct ccgaaatagc tttagggcta gcgtcgacat tagagattct tggaggtaga
     9661 gcactgtttg ggtgaggggt ccatcccgga ttaccaatct cagataaact ccgaatgcca
     9721 atgaattatg gtcggcagtc agactgcgag tgctaagatc cgtagtcgaa agggaaacag
     9781 cccagaccac cagctaaggt cccaaaataa ttgttaagtg gaaaaggatg tggggttgca
     9841 cagacaacta ggatgttagc ttagaagcag ctattcattc aaagagtgcg taatagctca
     9901 ctagtcgagt gaccctgcgc cgaaaatgta ccggggctaa aacaatttac cgaagctgtg
     9961 gataccttta taggtatggt aggagagcgt tctatgtgtg atgaaggtat accgtgagga
    10021 gtgctggaac gcatagaagt gagaatgccg gtatgagtag cgaaagacag gtgagaatcc
    10081 tgtccaccgt aagactaagg tttccagggg aaggctcgtc cgccctgggt tagtcgggac
    10141 ctaaggagag accgaaaggt gtatccgatg gacaacaggt tgatattcct gtactagagt
    10201 atgtagtgat ggagggacgc agtaggctaa ctaaagcaga cgattggaag agtctgtcta
    10261 agcagtgagg tgtgaattga gtcaaatgct taattctata acattgagct gtgatgggga
    10321 gcgaagttta gtagcgaagt tagtgatgtc acactgccaa gaaaagcttc tagcgtttaa
    10381 acatactcta cccgtaccgc aaaccgacac aggtagtcga ggcgagtagc ctcaggtgag
    10441 cgagagaact ctcgttaagg aactcggcaa aatgaccccg taacttcggg agaaggggtg
    10501 ctgacttaaa gtcagccgca gtgaataggc ccaagcaact gtttatcaaa aacacagctc
    10561 tctgctaaat cgtaagatga tgtatagggg gtgacgcctg cccggtgctg gaaggttaag
    10621 aggagtgctt agcgtaagcg aaggtatgaa ttgaagcccc agtaaacggc ggccgtaact
    10681 ataacggtcc taaggtagcg aaattccttg tcgggtaagt tccgacccgc acgaaaggcg
    10741 taatgatttg ggcactgtct caacgagaga ctcggtgaaa ttttagtacc tgtgaagatg
    10801 caggttaccc gcgacaggac ggaaagaccc catggagctt tactgcagtt tgatattgag
    10861 tgtctgtacc acatgtacag gataggtagg agtctaagag atcgggacgc cagtttcgaa
    10921 ggagacgctg ttgggatact acccttgtgt tatggccact ctaacccaga taggtgatcc
    10981 ctatcggaga cagtgtctga cgggcagttt gactggggcg gtcgcctcct aaaaggtaac
    11041 ggaggcgccc aaaggttccc tcagaatggt tggaaatcat tcgcagagtg taaaggtata
    11101 agggagcttg actgcgagag ctacaactcg agcagggacg aaagtcgggc ttagtgatcc
    11161 ggtggttccg tatggaaggg ccatcgctca acggataaaa gctaccctgg ggataacagg
    11221 cttatctccc ccaagagttc acatcgacgg ggaggtttgg cacctcgatg tcggctcgtc
    11281 gcatcctggg gctgtagtcg gtcccaaggg ttgggctgtt cgcccattaa agcggcacgc
    11341 gagctgggtt cagaacgtcg tgagacagtt cggtccctat ccgtcgcggg cgtaggaaat
    11401 ttgagaggat ctgctcctag tacgagagga ccagagtgga cttaccgctg gtgtaccagt
    11461 tgtcttgcca aaggcatcgc tgggtagcta tgtagggaag ggataaacgc tgaaagcatc
    11521 taagtgtgaa acccacctca agatgagatt tcccatgatt atatatcagt aagagccctg
    11581 agagatgatc aggtagatag gttagaagtg gaagtgtggc gacacatgta gcggactaat
    11641 actaatagct cgaggactta tccaaagtaa ctgagaatat gaaagcgaac ggttttcttg
    11701 aattgaatag atattcaatt ttgagtaggt attactcaga gttaagtgac gatagcctag
    11761 gagatacacc tgtacccatg ccgaacacag aagttaagcc ctagaacgcc ggaagtagtt
    11821 gggggttgcc ccctgtgaga
//
LOCUS       DAVMAH010000056        11721 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVMAH010000056 DAVMAH010000000
VERSION     DAVMAH010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11721
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.056"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            112..765
                     /locus_tag="VYO94_001710"
     CDS             112..765
                     /locus_tag="VYO94_001710"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV1760306.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            775..1239
                     /locus_tag="VYO94_001711"
     CDS             775..1239
                     /locus_tag="VYO94_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1760307.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1252..2520
                     /locus_tag="VYO94_001712"
     CDS             1252..2520
                     /locus_tag="VYO94_001712"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV1760308.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKVPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2534..2794
                     /locus_tag="VYO94_001713"
     CDS             2534..2794
                     /locus_tag="VYO94_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760309.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2805..4166
                     /gene="pdrM"
                     /locus_tag="VYO94_001714"
     CDS             2805..4166
                     /gene="pdrM"
                     /locus_tag="VYO94_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV1760310.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            4320..5288
                     /locus_tag="VYO94_001715"
     CDS             4320..5288
                     /locus_tag="VYO94_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV1760311.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPSLESAFEDIYAD"
     gene            5304..6296
                     /locus_tag="VYO94_001716"
     CDS             5304..6296
                     /locus_tag="VYO94_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV1760312.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHQTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6514..7557
                     /locus_tag="VYO94_001717"
     CDS             6514..7557
                     /locus_tag="VYO94_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV1760313.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     NTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7621..9306
                     /gene="lpdA"
                     /locus_tag="VYO94_001718"
     CDS             7621..9306
                     /gene="lpdA"
                     /locus_tag="VYO94_001718"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV1760314.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9370..10359
                     /locus_tag="VYO94_001719"
     CDS             9370..10359
                     /locus_tag="VYO94_001719"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV1760315.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGIKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10432..11502)
                     /gene="xerS"
                     /locus_tag="VYO94_001720"
     CDS             complement(10432..11502)
                     /gene="xerS"
                     /locus_tag="VYO94_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV1760316.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGCKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
BASE COUNT         3469 a         2196 c         2647 g         3409 t
ORIGIN      
        1 gtattcaaat cgtatatagt cgatttatta aatctttaga taaattgtaa aaagtggttt
       61 ccatagccac tttttgctat aatagaggca gtaaaaatga aggagtcagc tatggaacac
      121 tcgtcttggc atgctttgat taaggcgcaa ttacctgagg gttatttcgg gaaaatcaat
      181 cagtttatgg agcaggtcta ttctcagggg attatttatc cacccaagga aaaggttttt
      241 caggctctct tgacaacact gcttgaagaa gttaaggtgg taattctagg gcaagacccc
      301 tatcacggac caggtcaagc gcagggcttg agtttttctg tacctgactc tatcccagct
      361 ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg atatcggagt taagaaatct
      421 catgatttga cagcttgggc tgagcaagga gtcttgcttc ttaatgcttg tttgactgtt
      481 cctgctggac aggccaatgg tcatgctggt caaatctggg agccttttac tgatgctgtg
      541 attcaggtgg tcaatcatct agatagacca gtcgtttttg tactctgggg agcttatgca
      601 cgtaagaaga aggccttagt taccaatcct catcacttga ttatcgaatc agcccatcca
      661 agtcctttgt cggtttatag aggattttgg ggttccaagc ccttttccaa ggccaatgca
      721 ttcttaaaag agacaggaca agagccaatc gattggctta gataaggaga aaatatgcct
      781 cagttagcga cgatttgcta cattgataat gggaaagaac tgctcatgct ccatcgtaat
      841 aagaaaccca atgatgtcca tgaagggaaa tggattggtg tgggtggtaa gctagagaga
      901 ggagagacgc cccaggaatg cgcggtgcgt gaaatccttg aagaaacagg gctcaaagcc
      961 aagccagttc taaaaggtgt catcactttt cctgaattta caccagattt agactggtac
     1021 acctatgttt ttaaggtgac ggagtttgag ggcgacttga ttgactgcaa tgaggggacg
     1081 ctagaatggg ttccctatga tgaggttttg agcaagccga cttgggaagg tgaccacacc
     1141 tttgttgagt ggcttttaga ggataaaccc ttcttttcag ccaagtttgt ttatgatggg
     1201 gataaattgt tggataccca agttgatttc tatgaataaa ggagaaagca gatgctacta
     1261 atcaaaaatg gtcgtgtaat ggatcccaag tctggtttgg atcaagtttg tgatgtctta
     1321 gttcaagatg ggaaaattat caaaattgcg cctgagatca cggaagaagg agcagaaacg
     1381 attgatgcta ctggtcttgt ggttgctcct ggtttggtcg atattcatgt gcatttccgt
     1441 gaacctggtc aaacacataa agaagacatt catactggtg ccctggcagc cgctgcaggt
     1501 ggttttacta ctgtcgttat gatggctaat accagtccaa ccatttcaga cgtggagact
     1561 ttgcaagcag ttctccagtc agctgccaaa gagaagatta atgtcaagac agttgcgacc
     1621 attactaaaa actttaatgg taaaaacttg actgacttta aggcgctctt agaagctggt
     1681 gcggttggtt tctctgatga cggtattccg cttgagagca gtaagattgt caaggaagcc
     1741 atggaggaag ccaaaaaact caataccttt atcagccttc atgaggaaga tccaggtttg
     1801 aacggtgttc ttggctttaa tgaaaatatt gctagagaac atttccatat ctgcggtgct
     1861 actggggtgg ctgagtacgc tatgatggcg cgtgatgtca tgattgccta tgcaactaaa
     1921 gcccatgttc acatccagca tttgtctaag gaagaaagtg ttaaagtagt ggagtttgct
     1981 caggggttag gtgcagaagt cacagcagaa gtagcaccac agcatttctc taagacagaa
     2041 gcacttcttt taacacaagg tagcaatgct aagatgaatc caccgcttcg tttggaatca
     2101 gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca tcacagttat tgcgactgac
     2161 cacgcgcctc atcatgtaga tgaaaaaaat gttgaggata ttaccaaagt accatctggt
     2221 atgactggct tagaaacatc cctgtctctc ggcttgacct atttagtaga agctggtgag
     2281 ttgagcttga tggaattact tgaaaaaatg acatacaacc cagccaagct ttacaacttt
     2341 gaagcaggtt acttggctga gaatggtcca gcagatatca ctatttttga tgccaaggct
     2401 gaccgccttg tggactccca ttttgcttcc aaagcagcta attcaccatt catcggtgaa
     2461 accttaaaag ggcaggttaa atataccatc tgtaagggac aaatcgtcta tcaagcttga
     2521 taggagttag aatatgaatt attttcgaaa acgtagggag agacaagcga aatctaatag
     2581 tggaatttac tgtcccgcag ctaatcgttc caaaattcaa tatgaaacta aagaaaaagc
     2641 tgaccatgcg gttcaatatg ataacggagg tttagttaga agctattatt gtcgtacatg
     2701 tgcgtgttgg catactactt caaaatctaa taaacctccg ctaagtttga aaaactatgg
     2761 tctgaaactc tttggtttag ataaatcaga atagaaagag aagtatgtat aagacaaagt
     2821 gtttacgaga gaagttagta ttatttttaa aaattttctt cccaatcctg atttaccaat
     2881 ttgccaatta ttctgcctct tttgttgata ctgcaatgac aggtcaatac aacactatgg
     2941 acttggctgg tgtatctatg gcaaccagta tctggaatcc tttctttaca tttctaacag
     3001 ggattgtgtc agccttggtg cctatcattg gtcaccatct tggtcgaggc aaaaaggaag
     3061 aagttgcgtc tgatttttac caatttattt atttggcctt gggcctatct gtggtcttgc
     3121 tggggatggt acttttcttg gcaccaacaa tcttgaatca tattgggtta gaagcagcag
     3181 tagcggcagt agcggttcgc tatctttggt ttttatctat cgggattatc cccttgttgc
     3241 tctttagcgt cattcgttcc ttgctggatt cgctgggctt gaccaaactg tccatgtacc
     3301 tcatgctttt gttactccct ctcaatagcg gatttaacta tctcttgatt tacggtgcct
     3361 ttggtgttcc agaactggga ggggctggtg ctggtttagg aacatccttg gcctactggg
     3421 tcttgcttgg gatttctgtt ctggttttat ttaaacagga gaagctcaaa gccttacacc
     3481 ttgagaaacg aattccactt aatatggata acattaagga aggagttcgt ttaggtctgc
     3541 ctattggggg aactgtcttc gcggaagtgg ctatcttttc agtggttggc ttgattatgg
     3601 ctaagttttc gtccttgatt atagctagtc accagtcagc tatgaacttt tcaagtctta
     3661 tgtacgcctt tcctatgagt atctcatcgg ctatggctat tgtcgtttcc tatgaagtgg
     3721 gagccaagcg atttgatgat gcgaaaacct atattggtct aggaagatgg actgctctca
     3781 tttttgcggc cttcacccta accttccttt acatttttag gggaaatgtg gccagtcttt
     3841 atggtaacga cccaaaattt atcgatttga cagcgcgttt tttaacttat agtcttttct
     3901 tccagttagc agataccttt gcggcgccgc ttcagggaat tttgcggggg tataaggata
     3961 cagttattcc tttttacctt ggtttgcttg gttattgggg cgtagcaatc cctgtggcta
     4021 cgctatttga ttccctaaca gattttggag cttattctta ctggatcggc ttgattatta
     4081 gtttgattgt gagcggggcg ctctaccgtt ggcgtttaac tgtgattatg aagagatttg
     4141 aatctttagc aaaatccaaa tgctaaaaag tttgtgaaaa aatattcttg acaagaaaat
     4201 cccttgtttt cacggggttt tcttttttat tttgtgaaat ttcttttaga aaaactttga
     4261 cagtatttgc caaaagcggt aaaatagtaa ggtaagaaga aagttagaaa ggcaagaaga
     4321 tgtcaacttt agataaaaat cttttgctag aaatgttccg taagatggaa gaaatccgtc
     4381 gcatggactt aaaaattgca caattagtaa agaaagggaa agtgccagga atgacgcact
     4441 tttctgttgg tgaagaggca gctaacgtgg gggctatgtt agctctcaat ccagatgatc
     4501 tgattacctc aaaccaccgt ggacacgggc aagctattgc taaagggatt gacctcaacg
     4561 gaatgatggc tgaaatcctt ggtaaataca ctggaacctg taaagggaaa ggtggatcta
     4621 tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa tggtatcgta ggtggtggta
     4681 tggggatcgc tgtcggtgca gccctcagtc agcaaatgca aaataccggt aaaatcgttg
     4741 tctgcttctt tggagatggt gcgaccaatg aaggtgtttt ccacgaagca gtgaacatgg
     4801 cttctatctg gaacctgcca gtcattttct attgcattaa caacggttac ggtatctctg
     4861 cggatatcaa gaaaatgacc aatatagaac atatccatca acgtagcgcc gcttatggaa
     4921 ttcctggaat gttcatcgaa gacggtaaca atgtcatcga tgtctatgaa ggatttcaga
     4981 aagctgtgga ccatgttcgc agtggcaatg gtccagtctt gattgaaagt gtaacttatc
     5041 gctggctcgg tcactcatca tctgaccctg gtaaatatcg tacgcgtgaa gaagtggaat
     5101 tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta ccttattgaa aataacattg
     5161 caagtgccga agaattggaa gaaatccaag cgcaagtaaa ggaagcagta gaagcttctg
     5221 ttaaatttgc agaggaaagc ccattcccat cgcttgaatc agcctttgaa gatatttacg
     5281 cagactaagg agaaagagat aaaatggaaa caaaaacaat gtccttccgt gacaccatta
     5341 tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt gttcttgatg ggagaagacg
     5401 tcggtgtctt cggaggagac ttcggtactt ctgttggaat gcttgaagaa tttggtccag
     5461 aacgtgtccg tgactgtccg atttctgaag ctgccatctc tggagcagca gcaggagcag
     5521 ccatgacagg acttcgtcca atcgtcgata tgaccttcat ggacttctct gttattgcca
     5581 tggacaatat cgtcaaccaa gctgctaaaa cacgttacat gtttggtggt aaaggtcagg
     5641 ttccaatgac tgttcgttgt gcagctggta acggagttgg ctctgccgcc cagcactcac
     5701 aatctctaga gtcttggttt actcacattc caggacttaa ggttgtggca cctggaacac
     5761 ctgcggacat gaaaggcctg cttaagtctt ctatccgtga taacaaccca gttattatac
     5821 ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc agttgatcca gactacacaa
     5881 ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga tgtaacagtt gttacttatg
     5941 gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt agcagaagaa ggaatttcag
     6001 ttgaaattgt tgacccacgt acccttgttc cgcttgataa ggatatcatc ataaactcag
     6061 tgaagaagac tggtaaggtt gttctggtca acgatgccca ccaaacaagt ggctatatcg
     6121 gtgaaatttc agctattatt tcagaatcag aagcatttga ctatctagat gcaccaattc
     6181 gccgttgtgc aggagaagat gtgccgatgc cttatgcaca aaacctagaa aatgcaatga
     6241 ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac ttataacaaa gaatagggtt
     6301 acataagata agttatgtaa ataaaatgaa gctgacgaga aactttgtat cttttaggtg
     6361 cagagctctt cgtcattaat atcttagatt agagcacggg ctaaaagctc ggaaaaaaga
     6421 taaatctcct tggcttcatc gaagccatcg tcgatttcct atttttcagt cgcttttgac
     6481 gccctttgta tcataaatag aattggagag gtcatggctg atgacaagct aagagcgact
     6541 cctgcagcta gaaagttagc ggatgattta gggataaacc tctacgacgt ttctggctca
     6601 ggtgcaaacg gtcgtgtcca caaagaagac gtggaaactt ataaaaacac aaacgtggtt
     6661 cgcatttcgc cacttgcaaa acgaattgcc ctcgaacata acattgcttg gcaggaaatc
     6721 caaggaaccg gtcatcgtgg taaaatcatg aagaaggatg ttttggccct gcttcctgaa
     6781 aatatcgaaa acgatagcat caaatctcct gctcagattg aaaaagtgga agaagtccct
     6841 gataacgtaa caccatatgg tgaaatcgag cgtattccaa tgacaccaat gcgtaaggtt
     6901 attgcccaac gcatggttga atcttacttg actgcgccaa ccttcaccct caactatgaa
     6961 gttgatatga ctgaaatgtt ggctcttcgt aagaaggttc ttgagccaat catggaagca
     7021 actgggaaga agactactgt aacagacctt ctttcgcttg cagttgttaa gactcttatg
     7081 aaacacccat acatcaacgc ttcattgaca gaagatggca agactattat cactcacaac
     7141 tatgtcaatc ttgccatggc agttgggatg gataatggat tgatgacacc tgttgtttac
     7201 aatgctgaga agatgagtct ttcagaactg gttgtagcct ttaaggatgt tattggccgt
     7261 accttggatg gtaaattggc tccaagtgag ttacaaaatt caacattcac aatcagtaat
     7321 ttgggaatgt ttggtgttca gtcctttggt ccgattatta accaacccaa ctcagctatc
     7381 cttggtgtca gttcgacaat cgagaagcca gttgtcgtca atggtgaaat tgtgattcgc
     7441 ccaatcatga gtttaggatt aaccattgac caccgtgtcg tagatggtat ggctggtgct
     7501 aagtttatga aggacttgaa agagttgatt gaaacgccaa tctcaatgtt aatttaagag
     7561 caagagtatt catttttaag atatagataa aggaaggaag acatggcctt agaagtaatt
     7621 atgccaaaag ccggcgtgga tatgacagaa ggacaaatcg tccaatggaa taaaaaagtc
     7681 ggagaatttg taaaagaagg agaaatcctt ttggaaatca tgactgataa agtcagcatg
     7741 gaattggaag ccgaagaaga tgggtacttg attgccattc tcaaaggaga tggtgaaact
     7801 gtccctgtaa cggaagttat cggttacctt ggtgaagaaa gggaaaacat cccaacagct
     7861 ggagcagcat cgccagaagc tagctctgta cctgtagcaa gtacctcaaa cgatgatgat
     7921 aagagcgatg atgcttttga tatcgttgtg attggtggag gtcctgctgg ttatgttgca
     7981 gccattaaag ctgcccaatt cggcggtaag gttgcccttg ttgagaaatc tgaacttggt
     8041 ggaacctgct taaaccgtgg atgtattcca accaagacct accttcataa cgctgaaatt
     8101 attgaaaata tcggtcatgc tgcaaatcgt ggtatcgtga ttgaaaatcc taacttcact
     8161 gttgatatgg aaaaactttt agaaactaaa tctaaagttg ttaatactct tgttggtggt
     8221 gttgcaggac ttcttcgtag ctacggagtt actgttcata aaggaattgg tacaatcact
     8281 aaagacaaga acgtcttggt aaatggttct gaattgcttg aaaccaagaa aatcattctt
     8341 gctggtggtt caaaagtcag caagatcaac gtccctggta tggaatctcc acttgtcatg
     8401 actagtgatg acattcttga aatgaacgaa gtgccagaaa gccttgttat catcggtggt
     8461 ggagttgtcg gtatcgaact cggtcaggcc ttcatgacat ttggttcaaa agtgactgtt
     8521 atcgaaatga tggaccgtat agttccagct atggatgcgg aagtttctaa gaaccttcgc
     8581 ttgatccttg agcgtaaagg aatgaccatc ttgactggta ctaaactgca agaaatcatt
     8641 gaggaaaatg gtcaacttcg tatcaaggtt gaaggaaaag acgatatcat cgcaagcaaa
     8701 gctcttcttt caattggtcg tatgccagac cttgaaggta ttggagaggt tgagtttgaa
     8761 ttggatcgtg gttgtatcaa ggtcaacgaa tacatggaaa cttcagttcc aggcatttat
     8821 gcaccaggtg acatcaacgg tactaagatg ttggctcacg cagctttccg catgggtgaa
     8881 gtttccgctg aaaatgccct taaaggaaat catgcagttg ccaaattgaa tttgactcct
     8941 gcagccatct acactctccc tgaagtagca gcagtaggtt tgacagaaga acaagcccgt
     9001 gagaaatacg atgttgccat cggtaagttt aactttgctg ctaacggtcg tgctattgca
     9061 tctgacgcag ctcaaggttt cgtaaaagtt atcgctgata agaaatacgg agaaatcctt
     9121 ggtgtacaca ttattggtcc tgcagccgca gaattaataa acgaagcatc aagcatcatc
     9181 gaaatggaaa ttactgttga ggaaatgctg aagaccatcc acgggcaccc aacttactct
     9241 gaagtgatgt acgaagcgtt tgcagatgtt ctaggaatgg ccattcattc acctaagaaa
     9301 aaataaaacg aagatagatt agactggaag gttatttcca gtttctatca tataaagtaa
     9361 agggatatca tgaaatacat tatcaatcat tcaaatgaca ctgcttttaa tattgccttg
     9421 gaagaatacg cctttaaaca ccttttggat gaggatcaaa tcttcctact ttggattaac
     9481 aagccatcta tcattgttgg tcgtcaccag aacactatcg aagaaatcaa ccgtgattat
     9541 gttcgcgaaa atggtattga ggtagttcgc cgtattagtg gtggtggagc tgtttaccac
     9601 gatttaaata acctcaacta cacgatcatc tccaaagaag atgaaaataa ggcatttgac
     9661 ttcaagagct tctcaactcc ggttatcaat accctggctc aacttggggt taaagctgag
     9721 ttcacaggtc gtaatgacct tgagattgat ggtaagaagt tctgtggcaa tgcccaagcc
     9781 tatatcaacg gccgtatcat gcaccacggt tgcttgctct ttgacgttga tttgtcagtc
     9841 ctcgcaaatg cccttaaggt ttcaaaagat aaatttgaat caaaaggtgt gaaatccgtc
     9901 cgtgcccgtg taaccaatat tatcaatgaa ttaccaaaaa aaatcacagt cgaaaaattc
     9961 cgtgatttac tcttggaata catgaaaaaa gagtacccag agatgactga atacgtcttt
    10021 tcagaagaag aattggccga aatcaatcgc atcaaggata ctaagtttgg aacttgggac
    10081 tggaactatg gtaaatcacc tgaatttaac gtccgtcgtg gaatcaaatt cactagtggt
    10141 aaggttgaag tctttgctaa cgttactgaa tcaaaaatcc aagacatcaa gatttatggt
    10201 gacttctttg gtattgaaga cgttgctgca gtagaagatg tccttcgtgg ggtgaaatac
    10261 gaacgcgaag atgttcttaa ggcgctaaaa accattgata tcacacgcta cttcgctggt
    10321 attagccgtg aagaaatcgc tgaagcggta gttggataaa tcaaaaagaa gttggccaac
    10381 taaccaactt ctttttttga tatttattta cataatttaa aatacgtaaa atcataaact
    10441 atccagagca ttcttttgtt catcactaac aatatgggta tagaggtcag tgacttgtgt
    10501 gctagcatgt cctagttggt gactgactaa aacttgtgat ttagtcgcat catagagcct
    10561 agttgctagt gtatggcgca gtttatgggg tgttacacgc actttaaaat cctctgagta
    10621 tttagcaacc attttctcaa cgctagaagc atcgatacga ttaggaacac ctctgtagag
    10681 agttaaaaaa agggctgtat ctgttttttc cgttttatag cgttgattcc gaatggccag
    10741 ataattctct aaataaggtt tagcaaaagc agcgacattg actgagtcac gtttgcaacc
    10801 ttttcgagta acatcaataa ccatcatttt tagattgaga tctcttagat ctagattaac
    10861 agcttcagat aagcgaacac cagatgccaa gagaagggca ataatggcta aatctcgttc
    10921 tttatttttg ttgaatgatg agagagctcg atttgaaagc tgttgtgggt gctcttgatc
    10981 gatataagtt agaaaacctt ctgtttcatc acctagaaag agtttttgct tgatattttc
    11041 agctctggca gcaagggttt ctttcttttt cttggtggaa acttttttca ttacattacg
    11101 atagaaataa ggttccccct gatcgttttc aacctcctcg gttagatact tgtaaagact
    11161 agaaagtgct gataaggttc gattgatagt tgtctgtgaa acaccttgtt ttgttgtatt
    11221 agcattcagc aagggacgtt cacgtagata aaggataaag gattccatgt ctttcttaga
    11281 catattttcc aaaactgata aaggaatatc ggatatttta tcagcgtttg aaataccaga
    11341 ctccaaaacc cagctgaaaa atcggtcata ttccttaagg tattcgtaca gggttgtaaa
    11401 actgtagggc acagccagct tagattggta gtattccaga acataccagg gcatgagttg
    11461 ttttagtttg tcgattcgtt ccagtaaaat ctcacgtttc atgtattttc tccataagta
    11521 agtatactag tagtatagca tagacttgta tatttttcaa gaaaattata gtttttcaga
    11581 aagatgttat aggagttttt caaagtgata aaaagactta gacctacaaa caaaacagaa
    11641 taaggaaaat aatgaaaatc tcacccacta aacttctgtt aatactacat aactgaagag
    11701 ctatataagg agctatgaga t
//
LOCUS       DAVMAH010000057        11281 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVMAH010000057 DAVMAH010000000
VERSION     DAVMAH010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11281
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.057"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            9..1244
                     /locus_tag="VYO94_001721"
                     /pseudo
     CDS             9..1244
                     /locus_tag="VYO94_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1372..2394)
                     /gene="cbpF"
                     /locus_tag="VYO94_001722"
     CDS             complement(1372..2394)
                     /gene="cbpF"
                     /locus_tag="VYO94_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEV1760317.1"
                     /translation="MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRQEIAFRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWV
                     YDDGDWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQHLGNKWYYLRSSGAMATGWYQDGSTWYYLDAENGDMKTGWQNLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(2413..3234)
                     /gene="cbpG"
                     /locus_tag="VYO94_001723"
     CDS             complement(2413..3234)
                     /gene="cbpG"
                     /locus_tag="VYO94_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV1760318.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(3315..3554)
                     /locus_tag="VYO94_001724"
     CDS             complement(3315..3554)
                     /locus_tag="VYO94_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760319.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(3704..3970)
                     /locus_tag="VYO94_001725"
                     /pseudo
     CDS             complement(3704..3970)
                     /locus_tag="VYO94_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(3995..4306)
                     /locus_tag="VYO94_001726"
     CDS             complement(3995..4306)
                     /locus_tag="VYO94_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1760320.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(4231..4472)
                     /locus_tag="VYO94_001727"
                     /pseudo
     CDS             complement(4231..4472)
                     /locus_tag="VYO94_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(4473..5105)
                     /locus_tag="VYO94_001728"
     CDS             complement(4473..5105)
                     /locus_tag="VYO94_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1760321.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(5119..6114)
                     /locus_tag="VYO94_001729"
     CDS             complement(5119..6114)
                     /locus_tag="VYO94_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1760322.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGILDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(6111..6809)
                     /locus_tag="VYO94_001730"
     CDS             complement(6111..6809)
                     /locus_tag="VYO94_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV1760323.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAVTILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(6887..7897)
                     /locus_tag="VYO94_001731"
     CDS             complement(6887..7897)
                     /locus_tag="VYO94_001731"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV1760324.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLHTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(7881..8888)
                     /locus_tag="VYO94_001732"
     CDS             complement(7881..8888)
                     /locus_tag="VYO94_001732"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV1760325.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAESTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(8875..9828)
                     /gene="mvaD"
                     /locus_tag="VYO94_001733"
     CDS             complement(8875..9828)
                     /gene="mvaD"
                     /locus_tag="VYO94_001733"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV1760326.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YSVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMAFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(9810..10688)
                     /gene="mvk"
                     /locus_tag="VYO94_001734"
     CDS             complement(9810..10688)
                     /gene="mvk"
                     /locus_tag="VYO94_001734"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV1760327.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(10863..11141)
                     /locus_tag="VYO94_001735"
     CDS             complement(10863..11141)
                     /locus_tag="VYO94_001735"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1760328.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSAQVPWQ"
BASE COUNT         3380 a         2581 c         2018 g         3302 t
ORIGIN      
        1 ttaggtacat gattaaattg attgatcgtt acggaataga gttcggcaaa aaaggaaaaa
       61 atcgttacta ttctcctgat ttaaaacaag aaatgattaa taaagtctga catgaaggct
      121 ggactaaaga tagagtttct cttgaatact gtctcccaag tcgtacgata cttcttaact
      181 ggctagcaca atacaggaaa aacgggtata ctattgttga gaaaacaaga gggagagtac
      241 ctaaaatggg acgtaagcca aaaaagagac ctgaagagag gacagaatta gaatatcttc
      301 aagcagaaaa tgagtacctg agagcggaga atgccatcct aaaaaagtta agagaactcc
      361 gattgaagga ggaaaaagag aaagaagaaa gacagaaatt gttcaagaat taatgactga
      421 gttttcgtta gttcttcttc taaaatctat taaactagct cgttggacct actactatca
      481 cttgaaacag ctagacaaaa cagataagga ccaagagctt aaagctgaaa ttcaatccat
      541 ctttatcgaa cacaagggaa attatactta tcgtcggatt tatttagaac taagaaatcg
      601 tggttatctg gtaaatcata aaagaattca aggcttgatg aaagtactca atttacaagc
      661 taaaacgcga cagaaacgaa aatattcttc tcataaaaga cgttggcaag aaggcagaga
      721 atctcattca aggccaattt gaaggctcta aaacaatgga aaagtgctac acagatgtga
      781 cagaatttgc cattccagca agtactcaaa agctttactt atcaccagtt ttagatggct
      841 ttaatagcga aattatcgcc tataatcttt caacttcacc caacttagaa caagtacaaa
      901 caatgttgga acaggcattc acagagaagc actacgagaa tacgattctc catagtgacc
      961 aaggctggca ataccaacac gattcttatc atcggttcct agagagtaag ggaattcaag
     1021 catccatgtc acgtaaggga aacagcccag acaatagtat gatggagtcc ttctttggga
     1081 ttctgaaatc ggaaatgttt tacggttatg agaagtcgtt tcagtcgctt aagcaattgg
     1141 aacaagccat tatagactat attgattact acaacaataa acgaattaag gtaaaactaa
     1201 aaggacttag ccttgtgcaa tacagaacta aatccttcgg ataaattaat tgtctaactg
     1261 tttgagggca gtacagaaaa accttgatac tatgcgtttt ttgattgtga agacttttat
     1321 ccacctatta tacaaagtta agtatccatc acagtttaca attagccttc attacttaac
     1381 ccattcacca ttatagttta agtagtaacc acctactgtg gtattaacag ctaaagcacc
     1441 tgaatcatag gcatagtacc agttaccatt gacttggaac cagcctgttt tcatatctcc
     1501 attacttgca tttagatagt accaagtcga accttcctga taccaaccag ttgccatagc
     1561 tcctgatgaa cggagatagt accatttgtt cccaaggttt tgccaaccag ttttcatatc
     1621 gccattttca gcatctaaat agtaccaagt tgaaccatct tgataccagc cagttgccat
     1681 agctcctgat gaacggagat agtaccattt attaccaaga tgttgccaac ctgtttgcat
     1741 gatgccagtt gctggatcta gatagtacca tggagctgct tttagcttct cttcatcata
     1801 ggtaagaggg taatccttaa cccaaccacg tgctagctct ccaaccgtca atctgttgat
     1861 gcgagaatca aagccaccat ccttctgcaa ataataccag tccccatcat cataaaccca
     1921 accagttttt aaagtatgat aactacgctg atcttcaaaa taatagactc gtttctctgc
     1981 tgggctatca tattcttccc catgatgttt gttggtattt gtagcagttt ttgcttctaa
     2041 cacttgcttg ccaacaaatt cttgtagtac cccatcttga ccaaagtaaa accaatctgg
     2101 tctaaaagca atctcttgtc ttggagaagg accaatcgta acccccttgt gtggagcagg
     2161 tatatattgc cagccgacaa ccatctctcc ggataaagga tcaaaataat agtacttccc
     2221 atctatcact ctccagtagg tttcttttag atcccccttt ttgtagtagg ttctaccatt
     2281 ttcttggaca aactgccatc cttcagaatc atctgcaaat actgtactgg tccctagcaa
     2341 accgaagaaa aatgtggcta gtgcgacttg catcattttt ttcaaaagct tcattttata
     2401 tatcctccaa cattaaatcc actcaccaga tgaagcgaag ttataaactt taccatcgat
     2461 agtttggcta cctgtaacca ttgctccatt tgaattgaga taataccatt ttccatttac
     2521 tttttgccaa tctgtaagca tcttaccgga actgtctaaa taataccaag tatcatttat
     2581 ctcctgccaa cccgtttgtt tatcatgttg tctataatgg taccaactac catttatttt
     2641 cttccatcct tcaagagagt aacctttaag aaccgaataa ataaatggca aatttcgttc
     2701 atttaattta actgcactgt taatttgatt agctccatct cctaaagtat gcactcctac
     2761 tacacggtga ctagcatcat aaactgtaga tccactagac ccctctaaag tatcaacttg
     2821 gtaatccaag aacatgccat catcacttaa aacttgtttt ttatctgtat acatttgatg
     2881 aactttaaaa ttatatgatg gatagcctgt gatagtcaca gttattcctg tcaaattttt
     2941 ttgactagta ggaagaccca aagtccctaa ttttgcacca atgggctctt ctagaattaa
     3001 taaagccaag tcatattccc ttgcatcctt agaatttaaa tttctaaatt ccttcaaata
     3061 acgaacttcc tttactttga tctttccaaa tggttcttga cttggactaa cagccggaag
     3121 aacataaata tcatccgctt ctttcccata gtcatgtctg tagtagttgt gagccgctgt
     3181 aattaacaca ttatctttaa taaaattcgc acttcccctc ccttctacat tcattccatc
     3241 ggctactcca taatacttag ataaaaccat agctgaagtc gaatacggat actgtaaagt
     3301 attatcaatt ttaatcaaat catcattacc gataatactt ctgattgctt ttggtagtat
     3361 gaaccatatg ttggtgaaat ctcagataat gaagaatcat tagatcctgg acctttttct
     3421 agtgtctcac ttacctcata ttcttcaccc gtactagaaa taacactcaa agcagatact
     3481 gtcgataact ggctagccaa taaagtactc gcaataattg aaatacccaa ttttttataa
     3541 acagttttct tcattattgt atcctcctaa tgtaattata gcgtactatt ctaaatttct
     3601 taatctacta tagaatcaag aaatctacca ccttctttaa ataccctcca ttatcacata
     3661 aacaggtaaa cttttcaatt aatgactgcg cttttcaatc acgctagagg tacttacttg
     3721 cttctttgat actaagttca gccattcttt ccttgttttt ctcaataaag catgttaccc
     3781 aagtgggatt cgttttggag tagtctcgca gagtccagcc aatggcttta ttgataaaaa
     3841 attctgtttg gttcaagtta tgaaggagaa tcttttccat taattgagta ttggtcttct
     3901 cttttcttaa caactggtgg tcaatagcga cacgtctcag ccagatatta tctgataggc
     3961 tccattttat actcaatgaa aatcaaagag caaactagga agctagccgc agattgctca
     4021 aaacactgtt ttgaggttgc agatagagct gacgtggttt gaagagattt tcgaagagta
     4081 ttaagattat ttcttctagt tcagggtgtt catacaccaa actccctact actcgatcta
     4141 ggatatctac cgtgtcccac caggattttg tcacgactaa ctgctctagc ttaggcaaat
     4201 cggtttcctt tagataagac tgcattgctt tcaaatagtt agcagccaca tattggtatt
     4261 ttctaggctc cttttcccag caagtgtctg caaaatccca atcgataatc tttgtttttt
     4321 tcgcttctgg aaaatatttt tatagagttt atttctttca ggcaccgcaa tacctagaaa
     4381 agaaaattga tggcgcatat aggcttccat gggccttgct ttttagagtc ttttgctgct
     4441 tctagctcct caagtaaatc tgctaaactc atctaaaact cctcttgccc caccaaatgg
     4501 tgctgaaagg catagacagc cgcctgggta cgatcgctga cttcaagttt ggcaagaata
     4561 ttggacacgt gggtcttgac cgtcttgaga gagataaaga ggtcatctgc gatgcgctga
     4621 ttttcgtagc ccttggcgat gagttggaga acatctcgct cacgcgcagt caattcttca
     4681 tgaagttcca tatgattgcg gtggtattca accttcttgc taacctcttg ctcaatggcc
     4741 agctcgccag cagctacctt actgacggca tgaagcaatt catctgcact agaagtcttg
     4801 agcatatagc ctttggcacc agcatctaag actggcatga ttttttcatt gtccaaataa
     4861 gaggtcacaa tcaaaatctt ggcttcaggc cattctttaa ggattgctaa ggttgcgtca
     4921 atcccattca tctcaggcat gacaatatcc atgacaatga catctggacg cagttccaag
     4981 gccaagtcaa tcccttgaga cccgttggac gcctcaccca caacttctac atcgtcttgg
     5041 aggtcaaagt agcttttcaa gcccaatcgg accatttcat ggtcatctac tagtaaaatt
     5101 ttcatcttta ctcctttatc attccttatc taacagggga atacggatat caaccgccag
     5161 cccttgcttg ggagctgtca agagttgaac tgttccagcc atatcttcaa cccgctcctt
     5221 gatatttcgc agtccataac tcaagtcgtc taagatccct aactggaaac caatcccatt
     5281 gtccaccacc ttcagttgca attcaacatc tgtctgatag aggtagacat ctaggcaaga
     5341 tgcctgggca tggcggaggg tattgctaat caactcttgc aggatacgga agatatgctc
     5401 ctcgattttc ttaggcaatt tcgtcatatt ctgcttgaga ctaaccctaa gatcactctt
     5461 gtcctcaagc tcttttaaga gaatctgaat cccttctatc aagctcttct gctccagttc
     5521 aactggtcgc aaatgcaaga gcaaaacccg caaatccttc tgggctgttt ctaaaatagc
     5581 tgtgacactc tgcaactgga tctgcatctt ttctctatcc aatttcaaag cttgctgact
     5641 gatacccgat aaaatcatgt gggccgcaaa caactcctga ctgactgtat cgtgcaaatc
     5701 ccgagcaatt cgcttccgtt ctttctcgat gatttcctct tcctgagcaa ggctatgatt
     5761 ttcagctttt tgaagagcct ctgtcaaaag gttaagttta cctgataagg acttgaaact
     5821 ggcatccaaa tctggatctg caacctgaac cacttcttgc cctgctaata aacgcttgag
     5881 attagcctgc atttttctta gagaaagctc ttcgatccct cgccaaaaca gggctaagag
     5941 acaggtcatg gacatgctga aaaccaacaa taaaaagaca aatttttctg ttttttcgac
     6001 atcgtacaaa aagatagacc agtcaaaatc aagtatttcc agcaagctgt gggagaaaaa
     6061 aaagacaaat aggaaggagg tgagagcaat aatgacatag gcttgttttt tcatcctcta
     6121 accacctcca catcaccaat catagtggtc aagaaaatct tgacactctt gttactcttg
     6181 agatagtctt ttgtttcttg atgatagtgt tcattgcgga gggctcgctt gggctggttg
     6241 aaaaaagtca aatccccata gagacagtta acgctgagac tgacttccac atctacaggt
     6301 acgatgattt tggtcgttcc taccatcttt ctgaggataa tgacattgtc atgattggtt
     6361 aagatgaccc tctccagatg aatagtgtcc ttgcccatga agcgaaagag attgatatca
     6421 tcgaattggc aagtctggta gcttgaaaaa tgatgaagat ttccaaacca acgatttttc
     6481 tccttcttaa ccgtcacgac ctcttcaaaa accaaattgg tctgctcttt ttcctggttc
     6541 atcatcgggt aaagaagaaa gaggctatag ataaccgcaa caaaaatagc tagaatcaca
     6601 aaaggattga gcataacgat gaaaaagaag agaatggtta ccgctactaa aagaagatta
     6661 tttccctctt taccagtgta gtagcgaatc aaaagcaaaa agaggaatag tatcagcaga
     6721 aaacgcgaaa aatgctctga taccatcaaa atcagagctc ctgtcagaag acaggcttcg
     6781 ataaataaaa agattttaaa ttttctcata ggttcatcct ctcccttcta ttttatcaca
     6841 attcaaaaaa gtcacctcag tctgaggatg gaaaaaaagg cgctggttac gcctttttca
     6901 tctgatcatt tgcttctttt aattttccat aaagaagata gtctactttt tgtagatctg
     6961 ctatggtggc acagttaagg gaacacataa tcaagcgtag atctgctttc cagccttgga
     7021 caatgccaat cacttcttca actgtgtagg tttcaaccaa ttccagaacg gttcgtgaca
     7081 atcccacagc cttagcacca aaaaccaagc acttaatcat atccagcgga ttccgaaccc
     7141 ctccactaac caagagttcg accttatctt tccattcttg ggcattgaga agggcctgca
     7201 tggtagactg accccattga ttgaggtaat cacgctggcc actacgacgg ttttcgatat
     7261 aggcaaagct ggtgccacca cgacccgata ggtccactgt acgaacaccg aattcatagg
     7321 ctctttcgat tgtcttggca tccattccaa agcccacttc cttgaggaca ataggaacgg
     7381 gaatttgctt gctataatct gctagatgcg attgccagct tctaaacttc ctttctccct
     7441 cgggcatgag taattcctgc atgacattga catgcacttg caatagaaca ggattcatct
     7501 cttctacagt atgaagtcct aactcgacag gcttgtccaa tccaatattg gttccaagga
     7561 ggagattggg atgactagac ttgacagaaa aagaatcatc cgttggattt ttgagggctg
     7621 cgctataaga acccgttaca aataaaatac cacaggattc cgccacctga gccagctttt
     7681 gattgatttc tcttccctta ttacttccac cagtcatggc attgatataa aaaggaaagt
     7741 cccactttcg accagcaaac tctgtcgaaa gatcgatttc atccagattg taaagaggca
     7801 aggaagaatg aatcagctcc acctcatcaa agctattata ggaacttttc tgctcaaggg
     7861 catagaggat atgctcgtcc ttacgatttg tcgtcatgtc ctatcctttc ttgatataag
     7921 agctcaatcc ccagatcggc ccaacgattt tttaaggttt tggttgattc cgcatcaaaa
     7981 ctcagggcga tgccacagtc accaccacca gcaccactac tcttggcaac ggcctgcaaa
     8041 tcttgactgg cttctttcaa ctgtctaagc aaaggcgtgt aaatatctgt actcaagcct
     8101 tctaaaagct tgctggctac ttctacttgc tcgataactt tttcggcttt cccctgttcc
     8161 aaggcttcga ccaaagaaac caccgtttct tttgaggaac ttaaaaaatt ttgattgata
     8221 ttttgcttga tttgctggac catgtgactc gatacagcca cttccttggt ccatcccact
     8281 aagaaatcac attctaaagt tggtttcact tgtgaaattg aaaagcccca atcacgctcc
     8341 agaactgtcg ccaagttttc ttcttctaac caagcagcca ccttctggcg atcaaatgac
     8401 tggtagagaa ccaaatcctc tgccacaata caggcaaggt cgcccatgga accattgtct
     8461 cctcgcttaa gcaagacagc gctagtcagc ttgaacaaga gctcctgatc aacagaaaca
     8521 tcatacagag ccagtaaagc cttgacaacc aagacaacga cgctgccact agaacctaga
     8581 ccaaactttt tcccttctcg ttccattttg ccacagattt ctagggaaaa aggtcttaaa
     8641 ttctgaccgc gaacagcgag gaagtctccc atcaaagcaa tcgtttcttg aatcaagctg
     8701 tagtcaggat tgggccttaa gtccactgcg aaatcaaaca tatctgaata gatacggtag
     8761 ctgtcagaaa aagcaatctc agccctcata taaatgggaa tatcctttat caaagctaac
     8821 tgccctggct ctaaaatagc atattcacct gcccaataga gttttccgca agttttaaca
     8881 gcaatcatct tgactcaaat cctttgtttt tgacacaatc aagcgataac gctgaccgaa
     8941 aatttctgac aaatgctcca agtctttctc ctgacaaaag accttaacat tgggaccagc
     9001 atccatggta aagtagcagg cctctccttt ctcacgaagc tggcgaacaa aggccatagc
     9061 ctcataagag gcatccgtca gataagaaaa ggctggacta gcagtctttg tcgtagcatg
     9121 catagccaga gcatttttct ccgttaattc tccaatcttg gcaaaatcat tttccttgag
     9181 ataaatcagc atatcctgat agtccttctc agactgacga acccagtcgt caaaagtcgt
     9241 cgaggtttcc acacaaagtt tcatcccgtc acggctagag attggttttt tcttgtcctc
     9301 tagcaccaac ataatcatag ctagtttcaa gtctgtctct acagagtaaa tttctccact
     9361 atccttatcc caggctccta gcggtccata aaaactccga gaagaagagc ctgaggcaaa
     9421 cttggcttcc tgcgctaact gacttctatc caatccaagc ttgaaataag cattacaagc
     9481 cttgaccagg gcggacaaac cactagaact tgaggacagg cccgctgccg taggcatatt
     9541 gttttgagta tcgatacgga caaagccctc accagctgga cgataacggt caataatctt
     9601 actcatcttg gcatgctcga cctcattttg tagctgacca ttgatgtaaa attcgtcagc
     9661 tgttacattg gctggtaaag gcgacaaggt cgtctctgta tacatatttt ccaaagttag
     9721 agaaatactg ctagtagcag gcaccatctc tttttctttt ttctttcccc aatatttgat
     9781 aatagcaata tttgcgtagg aacgtactgt tacaggctct ctatccatgt ctgaacagct
     9841 cctttctctt ctaatctttc tgctagttct tgtgcgtgtg tcaaattggt taccaaggct
     9901 atgatacaac ctcctagccc accaccgctc atcttggcac ccagagcacc atggctaaga
     9961 gtcgtttcaa ccaaaaagtc tgcctcaggg ctactgactc caatttcttt taaatgtaaa
    10021 tgcgcttgac tgaggatttg tcccagtcct tcagcatctt tttgtgaaat cgcaacttct
    10081 gcttgctggg ttaattctcc caaggcatgc aaaaacggta gggcatcctt gcccttattt
    10141 tgaaccactt ggatggcttc acgagtatga ccataaacac ccgtatcggc aatcaccaaa
    10201 taggcggata aatccatctc aagttctgta aatcctacgt tcttgataaa gcgaataggt
    10261 tggtcactaa gacaggtctt agcatccaaa ccactaggat tcatatgggc aatcatttca
    10321 gctcgattga ccaagatttc tagtacatca tgaggcagat cagcctgata gtagtcaaat
    10381 actgcacgaa tggccgctat gctgatagcc gctgacgaac ccatcccccg tttctcaggg
    10441 atagccgagt caatctcaca acgaatgcag gcttctgtga tattcaaata ctccagtgag
    10501 gcataaaccg ccatggacaa ggtatcctcc tcataaaggc gccaaggact ctctgcagga
    10561 actaccttac aggtcacctc cacctccaaa agaggcaggg aaatggcagg ataaccgtaa
    10621 acgaccgcat gttcccctat taaaattatc ttactatgtg cctgaccgac accaactttt
    10681 tttgtcattt tttcctttta ctagacgaaa aaacgtctta tttttcatac aagtattaat
    10741 tctttcctat ctattttatt atattttcac aaaaaaagcg attgtttcca ttcacaatcg
    10801 cttctttcat tattgaaccc attcgccatt atagttgaca gaatagccat ctacggtcgt
    10861 attcactgcc aaggcacctg agcgctataa gcgtagtacc atctgccatt gacctggaac
    10921 caacctgtcg tcatagaacg acgaaagaaa ctccataccg ttaagtaaag aggaaagtcg
    10981 tgagggagca tgcgccattg acaacctgtt ttagtgacgt acaaagtctc attaacaagt
    11041 actcgtttcg gccatttata ggtgcggtgt ttggagaaat agggttcaat cttcgcccat
    11101 tcttgatcgt ttaaatcagt atcatatgct ttgcgtatca taactctagc ttaacatttt
    11161 tttgtgaata caggttctaa ataatcgacc acgaaaattt cttaagtgga aaacgcctta
    11221 tgaagtatgc tacgggaaac ttatgcactt aatttgacaa ttcaagatgt aaaaatatat
    11281 a
//
LOCUS       DAVMAH010000058        11174 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVMAH010000058 DAVMAH010000000
VERSION     DAVMAH010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11174
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.058"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..195
                     /locus_tag="VYO94_001736"
     CDS             <1..195
                     /locus_tag="VYO94_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1760329.1"
                     /translation="HNMIASDKEVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLE
                     DLSKISEPEKLYAYIAEATA"
     gene            233..535
                     /locus_tag="VYO94_001737"
     CDS             233..535
                     /locus_tag="VYO94_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1760330.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            543..1349
                     /locus_tag="VYO94_001738"
                     /pseudo
     CDS             543..1349
                     /locus_tag="VYO94_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1398..1862
                     /locus_tag="VYO94_001739"
     CDS             1398..1862
                     /locus_tag="VYO94_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV1760331.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDYLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2019..2444
                     /gene="lacA"
                     /locus_tag="VYO94_001740"
     CDS             2019..2444
                     /gene="lacA"
                     /locus_tag="VYO94_001740"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV1760332.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2475..2990
                     /gene="lacB"
                     /locus_tag="VYO94_001741"
     CDS             2475..2990
                     /gene="lacB"
                     /locus_tag="VYO94_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV1760333.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3001..3930
                     /locus_tag="VYO94_001742"
     CDS             3001..3930
                     /locus_tag="VYO94_001742"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV1760334.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            3932..4912
                     /gene="lacD"
                     /locus_tag="VYO94_001743"
     CDS             3932..4912
                     /gene="lacD"
                     /locus_tag="VYO94_001743"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV1760335.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSEPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            5146..5982
                     /locus_tag="VYO94_001744"
     CDS             5146..5982
                     /locus_tag="VYO94_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1760336.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLKGYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6018..6335
                     /locus_tag="VYO94_001745"
     CDS             6018..6335
                     /locus_tag="VYO94_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1760337.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6337..8031
                     /locus_tag="VYO94_001746"
     CDS             6337..8031
                     /locus_tag="VYO94_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1760338.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTVKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            8246..9652
                     /gene="lacG"
                     /locus_tag="VYO94_001747"
     CDS             8246..9652
                     /gene="lacG"
                     /locus_tag="VYO94_001747"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1760339.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9695..9952
                     /locus_tag="VYO94_001748"
     CDS             9695..9952
                     /locus_tag="VYO94_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV1760340.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDELEEFKNLFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(10231..10992)
                     /locus_tag="VYO94_001749"
     CDS             complement(10231..10992)
                     /locus_tag="VYO94_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1760341.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
BASE COUNT         3613 a         1913 c         2240 g         3408 t
ORIGIN      
        1 cacaatatga tagcttctga taaggaagta gaagtatccc tactcttctt tatcattaac
       61 aattcaagtt caagtcaaac aaatattctg gctcagttga tggacttttt cacaggaaat
      121 ggacatcttg aagacctatc aaaaatttcc gaaccagaaa aactttatgc ttacattgct
      181 gaagcaaccg cttaatcttg tctattaaaa aataaaatcg gaggaaatcc aaatgattaa
      241 aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa gtgctctaga
      301 agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg tgaaagatgt
      361 aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa cagaccttgg
      421 ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattctgta tcccagcaat
      481 gagcgttcca gtatttgaca atattagact tcctgcgaaa caaaatatgg tatagtagtt
      541 ccatgaatta tgaagcaagt aaacaactaa ctgatgcacg atttaagcgt cttgttggtg
      601 ttcaacgcac gacttttgaa gagatattag ctgtattaaa aacagcttat caacttaaac
      661 acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ccttcttatg gccactcttc
      721 aatatgtgcg agaatatcga acttatgaag aaattacggc tgattttggt atccacgaaa
      781 gcaacttaat ccgtcggagc caatgggttg aagtaactct tgttcaaagt ggtgttacga
      841 tttcaaaaac tcatcttagt gctgagaata cggtgattgt ggatgcaaca gaggtaaaaa
      901 taaatcgtcc taaaaaaatc aactagccaa ttattctggt aaaatagaaa tgtcattcta
      961 tggaacctca agcgattgtc acaagtcaag ggagaattgt ttctttggat atcgctgtga
     1021 actattgtca tgatatgaag ttgttcaaaa tgagtcgcag aaatatcgga caagctggta
     1081 aaatcttggt tgacagtggt tatcaagggc tcatgaagat atatcctcaa gcacaaactc
     1141 cacgtaaatc cagcaaactc aagccgctaa cagctgaaga taaagcctgt aaccatgcgc
     1201 tatctaagga gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatga
     1261 tttcaacaac ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgctg
     1321 gtattatcaa tcatgaacta ggattctagt tttgcaggaa gtctaataaa gaaactagca
     1381 aggtcagacc ttactttatt ggtggacatc caggatttaa ttgtcttcta cttgatgatg
     1441 aagtctatga agattattat ctagagtttg agaaagaaga gatttgctct gttccacgtc
     1501 ctttcccaga aacaggtatg ttggatttcc aagatagaag tccatggcta gagggacaaa
     1561 aagaaataga tcttagttat gatcttttca gcacagatgc agtgactttg gatgaattgc
     1621 aatctcgaac aattgccctt cgttctctta aacatgataa gggattgaaa gtgcattttg
     1681 cagaatttcc aaacctcatc atctggtcaa ctttgaacaa gggacctttc attacctttg
     1741 aaccatggtc tggcttgtca acattccttg aagaaggaga ttatttagaa gataagaaga
     1801 atgtttgtct cttagaagcc aatcaggttg aagaattagg gtttgagata gaagttttat
     1861 aaaaaagtaa aaaataaata acaaaaacaa acacaaactg ttgacttctt caaacaatag
     1921 tagtatatta tgtttgtgag gactaattga ctgtttttta aagacagcca atacactgct
     1981 ggaatccagc atagaaaaaa taaaaaggag tatacaatat gtctattgtt atcggtgcag
     2041 atgctgcagg tttgagattg aaagaagttg tgaaagactt cttagaaaaa gaaaacttcc
     2101 accttgtgga tgttacagct gaaggtcaag actttgttga tgtgactctc gctgttgctg
     2161 cagaagtaaa caaagaagaa caaaaccttg gtatcgtgat tgatgcttat ggagctggtc
     2221 catttatggt tgcaactaag atcaaaggaa tggttgctgc agaagtatct gacgaacgtt
     2281 cagcttatat gactcgtggc cacaacaact cacgtatgat cactatgggt gcacaacttg
     2341 ttggtgatga attggctaaa aacatcgcta aaggatttgt taacggtaaa tacgatggtg
     2401 gacgtcatca aatccgggtc gacatgttga acaaaatggg ctaattagat tacagtaaga
     2461 aaggtaagtt aaaaatgaga attgcaattg gatgcgacca catcgtaaca gatgaaaaaa
     2521 tggcggtttc agaatttttg aaatcaaaag gatatgaagt cattgacttt ggtacatatg
     2581 accatacacg gactcactac ccaatctttg gtaaaaaagt aggggaagct gtaactagcg
     2641 gccaagctga tcttggggta tgtatctgtg gtactggtgt tggtatcaac aacgctgtaa
     2701 ataaagttcc aggtgttcgt tctgccttgg ttcgtgatat gacaacagcc ctttatgcta
     2761 aagaacaatt gaacgctaac gttatcggct ttggtggtaa gattactggt gaattgctta
     2821 tgtgtgatat catcgaagct ttcattcatg ctgaatacaa accatctgaa gaaaacaaga
     2881 aattgattgc gaaaattgaa caccttgaaa gtcacaatgc tcaacaaaca gacgcaaact
     2941 tctttacaga attccttgaa aaatgggatc gcggagaata ccacgactaa gaggtgacct
     3001 atgattttaa cagtcacaat gaacccatcc attgatattt cctatccctt ggatgagttg
     3061 aagattgata ctgtcaatcg tgtggtggat gtaaccaaaa cggctggtgg taagggactc
     3121 aatgttaccc gagtactttc agaatttggc gattctgttc ttgctactgg tttagtgggt
     3181 ggcaaacttg gtgagttttt ggttgaacat atcgataatc aagtaaagaa agatttcttc
     3241 tcaattcagg gagaaactcg taactgtatc gctattctcc acggagacaa ccaaacagaa
     3301 gttcttgaaa aaggtcctga agtattggaa caggaaggtc aagacttttt ggaacatttc
     3361 aaaaaactct tggagtcagt tgaagtagta gccatctcag gtagtctgcc agctggcctt
     3421 ccagttgatt actatgcgag cttggtagaa cttgctaatc aagctggcaa gcctgtagtc
     3481 ttggactgct caggtgcagc acttcaggct gttcttgaat caccccataa accaacagtc
     3541 atcaaaccaa ataatgaaga attgtctcag cttcttggaa gagaagtttc tgaggatttg
     3601 gatgaattaa aagaagtact tcaagaacct ttgtttgcag ggattgaatg gattatcgtt
     3661 tcacttggtg ccaacggtac ttttgccaaa catggtgaca ctttctacaa ggtagatatt
     3721 cctagaattc aggtggtaaa tcctgttgga tctggagact ctactgtggc aggaatttct
     3781 tcaggacttc ttcacaaaga atcggatgca gaattactca tcaaggcaaa tgtccttggt
     3841 atgctcaatg ctcaagaaaa aatgactggt catgtcaaca tggccaacta tcaagctcta
     3901 tatgatcaat taatagtaaa agaggtataa aatggcttta acagaacaaa aacgtgtacg
     3961 cttagaaaaa ctttctgatg aaaatggtat catctcagct cttgcatttg accaacgtgg
     4021 tgctttgaaa cgcctcatgg ctcaacacca aacagaagaa ccaactgtgg cccaaatgga
     4081 agaacttaaa gtcttggtag cagatgaatt gactaaatat gcttcatcta tgcttcttga
     4141 ccctgagtat ggacttccag caactaaagc tcttgatgaa aaagctggtc ttctccttgc
     4201 ttatgaaaaa acaggttatg acacaacaag cacaaaacgc ttgccagact gcttggatgt
     4261 ttggtctgca aaacgtatta aagaagaagg tgcagatgca gttaaattct tgctttacta
     4321 tgatgtagat agctcagacg aactcaatca agaaaaacaa gcctacatcg aacgcatcgg
     4381 ttctgagtgt gtggctgaag atatcccatt cttccttgaa atccttgctt acgatgaaaa
     4441 aattgcggat gcaggttctg tagaatacgc taaagtaaaa ccacacaaag ttatcggcgc
     4501 tatgaaagtc ttttcagaac cacgctttaa cattgatgtt ttgaaagttg aagttcctgt
     4561 taacattaaa tatgttgaag gcttcgctga aggtgaagta gtttatacac gtgaagaagc
     4621 agcagccttc ttcaaagcgc aagatgaagc aacgaacttg ccatacatct acttgagtgc
     4681 tggtgtatca gctaaactct tccaagatac tcttgtattt gctcatgaat caggtgcaaa
     4741 ctttaacgga gttctttgtg gccgtgctac atgggcagga tcagttgaag cttacatcaa
     4801 agatggtgaa gcagcagctc gcgaatggct tcgcacaact ggatttgaaa acattgacga
     4861 actcaacaaa gttcttcaaa gaacagcaac ttcatggaaa gaacgtgtgt aagaaagtcc
     4921 tcctagttta ggaacatgaa tctaaaaaaa tttaaaaaaa gttgtatgta aaggtttaca
     4981 aaacaaccga cttgtgctat acttaaatca caagttaata caaggtgagt gttactaagt
     5041 aatattaggc atgatcacag gtgaattaga aatcagctga ttttctagtt catttgtggt
     5101 cattttttgt actcatatac ctttaagata taaaaggagg ttgacatgta tcgaattcta
     5161 aatccaatga atcacaatgt ctcgcttgtc agaaatgata agggagaaga ggtgattata
     5221 attggtaagg ggattgcatt cggaaaaagg aagggggatt tgattgctga aaatcaggtt
     5281 gagaaaatct ttcggatgaa gaccgaagag tccagagaaa actttatggc tcttctcaaa
     5341 gatgttccgc ttgattttat cacagtgacc tatgaaatca ttgataagct atcaaagaaa
     5401 tatcattatc cgattcaaga gtatctctat gtaaccttga cagatcatat ttactgttct
     5461 tatcaagctc taactcaagg aaggtacaag gatagtaatc tgccggatat ttccgctaag
     5521 tatcctgtcg cttttcaaat cgcaaatgaa gcttttgaaa tttaccgtca gaagctagca
     5581 gatcattttc ctgaggacga gattattcgg attgcttatc atttcatcaa tgctgaaggt
     5641 gaaaatgaag tggaacttgt ggagtcgatt gataagagga aagaaattct caggaatgtt
     5701 gaagaagtgc taaagggtta tgcaattcaa cgaaccaaaa aaaataatca tttctatgat
     5761 cgctttatga ttcatttgaa ttatttcttg gattatttag acagatctag agatgataac
     5821 caatcacttc tggatatgga agatcatatt aaacaatcct atccaaaagc cttcgagatt
     5881 ggttccaaga tctatgatgt gattacgcaa catacgggtc ttgatttgta taaaagtgaa
     5941 cgagtttatc tagttctaca tatccaacgt ttattgtcat aaaaatttat ttaaaactat
     6001 ataaggagaa ttctatcatg aatagagaag aagtaacatt gttaggtttt gaaatcgtag
     6061 cctatgctgg cgatgctcgt tcaaaactat tggaagcctt gaaggctgct gaagctggtg
     6121 attttgaaaa agcggacgct ctggtagagg aagctggtag ctgtattgca gaggctcacc
     6181 acgcgcaaac aagtctattg actaaggaag cttctggtga ggacttagcg tatagtgtga
     6241 ccatgatgca tggtcaagat cacttgatga caactatctt gttaaaagac ctaatgcacc
     6301 atttaattga actttacaag agaggagtta aataaaatgg ataagttaat aatttttatt
     6361 gagaaaggaa agcctttctt tgagaaatta tcgagaaata tatacttaag agcgataaaa
     6421 gatggtttta tttccagtat gccagcagta ttattctcaa gtatttttat actaatagct
     6481 gctgtgccca atatttttgg gtttaaatgg tctgatgaac agttagcttt tattttgaaa
     6541 ccttacaact actcaatggg aattttagct ctcttagtag ctgggacaac tgcaaaatcg
     6601 ttaacagatt cagttaatac acgtagtatg gagaaaacca accaaatcaa ctacatgtca
     6661 acttttttag cagctgttgt tggattgtta atactggcag ctgatccaat tgaaggtgga
     6721 tttgctaatg gtcttttagg tactagagga ttacttactg catttttggc agcttttatt
     6781 acagtaaata tctataaagt atgtattaaa aataatgtaa ccattagact tcctgaagag
     6841 gttccaccaa atattgcaca agtttttaaa gatgttattc cgtttgcctt atctgttctt
     6901 tcaatatatg gattggattt aattgttaga aatatttttg gtacaaatgt agcagaatct
     6961 gttggtaaaa tattagcccc tctattttca gctactgatg gttatatcgg tttagctatt
     7021 gtatttggtg cttatgcttt cttttggttt gttggaattc atgggccatc tgttgtagaa
     7081 cctttaattg tagctatcag ttatgcaaat atagaagcta atgttcagct tgtgcaagct
     7141 ggtatgcacg cagataaaat tttaaatcca gttactcaaa cttttgttgt aacaatgggt
     7201 ggtactggtg caacactagt agttccattt atgtttatgt ggttatgtaa atcaaaaaga
     7261 aatagaattg tcggacgtgc gtctgtagtt cctactttct ttggcgtaaa tgaaccaatc
     7321 ctatttggtg ctccaattgt tttaaatcct atcttcttta ttccgtttgt tactgctcct
     7381 attatcaatg tttggattat gaaatttttt gtagatgttc tacaaatgaa tagtttcagt
     7441 attattttac cttggacaac acctgctcca attggtattg ttatgggaac ggcgctggct
     7501 ccattgtcat tcgtcttggc tataacttta atcattatcg acactttaat ctattatcca
     7561 tttgttaaag tttatgacca tcaaatttta gaagaagaac ggaaaggaaa ctcttcatct
     7621 gaattgaaag aaaaagttgc tgcaaacttc aacactgtaa aagcggatgc tattcttgaa
     7681 aaagcaggtg tcgatgcagc acaaaatacc atcactgaag aaacaaatgt cctcgttctc
     7741 tgtgctggtg gaggtacaag tggactcctt gcaaatgctt tgaataaggc agcagcagaa
     7801 tacaatgtcc ctgtgaaagc agcagcaggc ggctatggtg ctcaccgtga aatgttacca
     7861 gagtttgatt tggttatcct tgctcctcaa gttgcttcaa actttgaaga tatgaaggca
     7921 gaaacagata agctcggtat taaactagcg aaaacagaag gcgctcaata catcaaatta
     7981 actcgtgatg gaaaaggtgc cctagcattc gtacaagaac aattcgatta aggctaggaa
     8041 ctgtgaaaca gtctcctatc gttacggaaa tcgctatggc gaatttccta atcgccttat
     8101 taattcgtcg gtaaaaagat atcgttttta cctcctcatg tcacaattcg gtgacttggt
     8161 acaagaagtg agatggagaa ggatggctca ctgactcctc tcctctcact tttactttat
     8221 ttaaatcaag aaataggtga aaaaaatgac aaaaacactt ccaaaagact ttatttttgg
     8281 tggcgcaaca gctgcctatc aagcagaagg tgctacacat actgatggta aaggaccagt
     8341 agcgtgggat aaatatcttg aagataacta ctggtacact gcagaaccag ccagtgattt
     8401 ttacaatcga tatccagttg acctcaagct agcagaagag tatggtgtca atggtattcg
     8461 aatttctatt gcttggtcac gtattttccc gactggttac ggccaagtaa atgctaaagg
     8521 tgttgagttt tatcataatt tatttgcaga gtgtcacaaa cgtcatgttg agccttttgt
     8581 aactcttcat cactttgaca cgccagaagc tctccactca aatggagact tcttaaaccg
     8641 tgaaaatatc gaacattttg tagactacgc tgccttctgt tttgaagaat ttccagaagt
     8701 aaactattgg acaaccttta atgaaattgg accaatcggt gatggtcaat atttggttgg
     8761 gaaattccct ccaggtatcc agtacgacct tgccaaagtc tttcaatcac accacaatat
     8821 gatggtgtct catgcacgcg cggtaaaatt gtacaaagag aaaggctata aaggggaaat
     8881 tggtgttgtt cacgccctgc caactaaata tcctctagat cctgaaaatc cagcagatgt
     8941 tcgtgcagct gagttggaag atatcatcca caataaattc atcttagacg caacttatct
     9001 aggtcgctat tcagctgaaa ccatggaagg tgtcaaccat atcttatcag tcaatggtgg
     9061 tagtttggat cttcgtgaag aagattttac agcattagaa gctgcaaaag acttgaatga
     9121 tttcctagga atcaactact atatgagtga ctggatggaa gcctttgatg gagaaactga
     9181 aattatccat aatggtaaag gtgaaaaagg aagctctaag tatcaaatca aaggtgttgg
     9241 tcgtcgtgta gctcctgact atgtaccacg cacggattgg gattggatta tctaccctca
     9301 aggtttgtat gaccaaatca tgcgtgtgaa gaaagattat cctaactaca agaagattta
     9361 catcactgaa aatggtctcg gctataaaga tgagttcgtt gataacactg tttacgatga
     9421 tggtcgtatt gattacgtga aacaacactt ggagatcttg tctgatgcga ttgcagatgg
     9481 agctaatgta aaaggttact tcatttggtc attaatggat gtcttctcat ggtcaaacgg
     9541 ttatgagaaa cgttatggtc tcttctacgt agattttgaa actcaagaac gttatcctaa
     9601 gaaatcagct cactggtaca agaaagtagc ggaaactcag attatagact agtagaatta
     9661 gtcattagat atagaatttt agtgagtcaa aaagatgttc aaagatttta tccaatctat
     9721 ttatgaaaaa gtttatatta taaatttcga aaaatgctct caaataccgt gtttgacgag
     9781 tgaagaattg aaaagtcttg gaaaatggta tgtctcgact ggtaaagaat ggatttgtca
     9841 ttcagatgat gagctggaag aatttaaaaa tctattttta aattttatca atcctgaaga
     9901 atgggatact atctcctttg attcagattt tatgccgttt caacaatcgt aaccaatttc
     9961 tcaaaaaagt taaatcttat atttagtact ctgtaaaact cttatctaat cacgttgctt
    10021 atactcaatg aaaatcaaag agcaacttta aacgaggaag cgagtcgcag atttctcaat
    10081 gcatagcttt gaggaattgg gcaaaaagtc tttgatatag aaaaacgcat agtatcaggt
    10141 gttgaaacac ctgatactat gcgttttatt gtgggaagat ttactttttt tcttctgaaa
    10201 ttgagttgtt acccaggctc tttcagttta ttaaggcttg atgactttaa tgtgtttaga
    10261 tagcttaaaa aggattgaat cacttagttt agaatctgaa acaatagtat caagatttga
    10321 tacattataa aaagtataaa aatcaaactt attgaactta ctatgatctg cgagtaaata
    10381 ttttttatta gaattattta aagcgatgcg ttgagcctct ccctcttcct cgctaaaagt
    10441 agctagagct ccgttttgaa taccattaca gctaacgaaa gctttagaaa attggagatt
    10501 agagagattt tgtagggtca atgtaccaac aaaagcacct gtaatatcgc gataatttcc
    10561 acctattaaa atcaaatctg ttaattttcg ttcgcttaaa atcagaaaaa caggtagact
    10621 gttggttacg acgcggatat tgtcaatagg caactcacgc gcaaaaaact ctaatgttgt
    10681 tcctggtcca atgaaaatag tttctctttc ttctactaga ctgcctgcaa aatgggctat
    10741 ttcttgtttt tctgccgttt ggagggcttg tttttcaata tttgatcgct cattagtcaa
    10801 aagggagttg gttcgaagtt tttcagctcc accatgcaca cgaatcagca aatctttatc
    10861 agctaattcc tgtaaatagc gccttgcagt catatctgaa acggctattt cgtccataat
    10921 ctgtttaact gttatggttc ctttactatt tactatctct aaaattttgg ttaatttttc
    10981 ttgtttgagc atattatcac ctcgtttcct actactatct taccataaac tagctcatca
    11041 ttcaaataca aaaacaacaa aataaaacaa aaacaaaaat atcgaagttt attttcaaaa
    11101 ctttcgatat ttttattaag ttattatttt gttgtttcta gtttactttt tgatggttaa
    11161 gagtggtgga gaat
//
LOCUS       DAVMAH010000059        10971 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVMAH010000059 DAVMAH010000000
VERSION     DAVMAH010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10971
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.059"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            14..736
                     /locus_tag="VYO94_001750"
     CDS             14..736
                     /locus_tag="VYO94_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1760342.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            733..1581
                     /locus_tag="VYO94_001751"
     CDS             733..1581
                     /locus_tag="VYO94_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1760343.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            1613..2542
                     /gene="psaA"
                     /locus_tag="VYO94_001752"
     CDS             1613..2542
                     /gene="psaA"
                     /locus_tag="VYO94_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV1760344.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            2665..3156
                     /gene="tpx"
                     /locus_tag="VYO94_001753"
     CDS             2665..3156
                     /gene="tpx"
                     /locus_tag="VYO94_001753"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV1760345.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(3252..5960)
                     /locus_tag="VYO94_001754"
     CDS             complement(3252..5960)
                     /locus_tag="VYO94_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1760346.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQCSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATDQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMSQSAVSSVVQNASAIRLFDSVASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTTKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(5962..6663)
                     /locus_tag="VYO94_001755"
     CDS             complement(5962..6663)
                     /locus_tag="VYO94_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760347.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDVLNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            complement(6913..9324)
                     /locus_tag="VYO94_001756"
     CDS             complement(6913..9324)
                     /locus_tag="VYO94_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1760348.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            complement(9377..10069)
                     /locus_tag="VYO94_001757"
     CDS             complement(9377..10069)
                     /locus_tag="VYO94_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV1760349.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            complement(10120..10410)
                     /locus_tag="VYO94_001758"
     CDS             complement(10120..10410)
                     /locus_tag="VYO94_001758"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760350.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETAKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            complement(10604..10960)
                     /locus_tag="VYO94_001759"
     CDS             complement(10604..10960)
                     /locus_tag="VYO94_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760351.1"
                     /translation="MSGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGATAGAFSGV
                     ALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGWVGGILVII
                     GGSLFLATLKKFKSEE"
BASE COUNT         3202 a         2530 c         2057 g         3182 t
ORIGIN      
        1 ggaatataag tttatgatac gtatcgaaaa cctcagtgtc tcctacaaag aaacgttggc
       61 acttaaggat atttcactag tgctccatgg accaacaatt accggcatca ttggtccaaa
      121 cggcgctggg aaatcaacac tattaaaagg tatgttggga attatcccac atcaaggtca
      181 ggcatttctc gatgacaagg aagttaaaaa atccttacac cgaattgcct atgtcgaaca
      241 aaaaatcaat atcgactaca actttcccat caaggtcaag gaatgcgtct cgttaggact
      301 atttccctct attcctctct ttcgaagttt aaaggctaaa cattggaaga aagtgcaaga
      361 ggcccttgaa atcgtcggcc tagctgacta cgctgaacgt caaattagtc aactgtctgg
      421 aggtcaattc cagcgggtct tgattgccag atgtttggtg caggaagccg actatatcct
      481 cttggatgaa ccctttgctg ggattgactc tgtcagtgag gaaatcatca tgaatacgct
      541 gagagatttg aaaaaagctg ggaagacggt tctcatcgtt caccacgacc tcagcaagat
      601 tccccactac ttcgatcaag tcttacttgt caatcgagaa gtgattgcct ttggtccaac
      661 aaaagaaact tttaccgaaa ccaatctaaa agaagcttac ggtaatcaac tctttttcaa
      721 tggaggtgac ctatgattgc agaatttatc gatggattgc aaaaattcca tttcctacaa
      781 aatgccttga taacagctat tgtcgtcggg attgtagctg gagccgtggg atgtttcatt
      841 attctacgcg ggatgtcact catgggagat gccatttcac atgctgtctt accaggtgta
      901 gccctctcct tcatcttggg ccttgacttc tttatcggag ccattgtctt tggattgcta
      961 gctgccatca tcattaccta catcaaagga aactcgatta tcaaaagcga taccgccatc
     1021 ggcattacct tttcttcttt cttagccctc ggtatcatct tgattggtgt cgctaaaagt
     1081 tcaactgacc ttttccatat cctttttggt aatatcctgg ccgtccaaga tacggatatg
     1141 tttattacta tgggtgtggg ggcagccatc ctcttgttaa tctggatttt cttcaagcaa
     1201 ctcttgataa cttcctttga tgaactcttg gctaaagcca tgggaatgcc tgtcaatttc
     1261 tatcactacc ttctcatggt actcctgact ctcgtgtctg tgacagccat gcaaagtgtc
     1321 ggaactatcc tgattgtagc catgctgatt accccagctg caactgctta tctgtatgct
     1381 aatagtctga aaagcatgat tttcctttcc tcaaccttcg gagctactgc ttcagttttg
     1441 ggactcttta ttggctatag ttttaatgtt gcggcaggtt ctagtatcgt gcttacagct
     1501 gctagtttct ttctcattag cttctttatc gctcccaaac aacgatattt gaaactgaaa
     1561 aataaacatt tgttaaaata aggggcaaag ccctaataaa ttggaggatc taatgaaaaa
     1621 attaggtaca ttactcgttc tctttctttc tgcaatcatt cttgtagcat gtgctagcgg
     1681 aaaaaaagat acaacttctg gtcaaaaact aaaagttgtt gctacaaact caatcatcgc
     1741 tgatattact aaaaatattg ctggtgacaa aattgacctt catagtatcg ttccgattgg
     1801 gcaagaccca cacgaatacg aaccacttcc tgaagacgtt aagaaaactt ctgaggctga
     1861 tttgattttc tataacggta tcaaccttga aacaggtggc aatgcttggt ttacaaaatt
     1921 ggtagaaaat gccaagaaaa ctgaaaacaa agactacttc gcagtcagcg acggcgttga
     1981 tgttatctac cttgaaggtc aaaatgaaaa aggaaaagaa gacccacacg cttggcttaa
     2041 ccttgaaaac ggtattattt ttgctaaaaa tatcgccaaa caattgagcg ccaaagaccc
     2101 taacaataaa gaattctatg aaaaaaatct caaagaatat actgataagt tagacaaact
     2161 tgataaagaa agtaaggata aatttaataa gatccctgct gaaaagaaac tcattgtaac
     2221 cagcgaagga gcattcaaat acttctctaa agcctatggt gtcccaagtg cctacatctg
     2281 ggaaatcaat actgaagaag aaggaactcc tgaacaaatc aagaccttgg ttgaaaaact
     2341 tcgccaaaca aaagttccat cactctttgt agaatcaagt gtggatgacc gtccaatgaa
     2401 aactgtttct caagacacaa acatcccaat ctacgcacaa atctttactg actctatcgc
     2461 agaacaaggt aaagaaggcg acagctacta cagcatgatg aaatacaacc ttgacaagat
     2521 tgctgaagga ttggcaaaat aagcctctga aaaacgtcat tctcatgtga gctggcgttt
     2581 tttctatgcc cacatttccg gtcaaatcat tggaaaattc tgactgtttc agatacaatg
     2641 gaagaaaaaa gattggagta tcctatggta acttttctcg gaaatcctgt gagctttaca
     2701 ggtaaacaac tacaagtcgg cgacaaggcg cttgattttt ctcttactac aacagatctt
     2761 tctaaaaaat ctctggctga ttttgatggc aagaaaaaag tcttgagtgt cgttccttct
     2821 atcgatacag gcatctgctc aactcaaaca cgtcgtttta atgaagaatt ggctggactg
     2881 gacaacacgg tcgtattgac tgtttcaatg gacctacctt ttgctcaaaa acgttggtgc
     2941 ggtgctgaag gccttgacaa tgccattatg ctttcagact actttgacca ttctttcggg
     3001 cgcgattatg ccctcttgat caacgaatgg cacctattag cacgcgcagt ctttgtcctc
     3061 gatactgaca atacgattcg ctacgttgaa tacgtggata atatcaattc tgagccaaac
     3121 ttcgaagccg caattgcagc tgctaaagcc ctatagaaaa aatcctctgt cacaaagagt
     3181 tccctgctct ttgaaacgga ggatttttga atattagtaa atagaagttc aatcagctaa
     3241 aaataactac cttactctac agatttcagg gcttctaaca tatcaacctt tctcagataa
     3301 taattgacga agaaaccaag caaggtcaaa atgatgctta ctgctgccac tgggattaca
     3361 tagacttccc agcctacctg cggataaaag agaatagtcg caggcgaaat catttgaatc
     3421 aaaaattggt gtaaatagaa accagctacc agaccaagta cgattcccac aagggatagc
     3481 acaatcgtct cacggtaaat gtagagggtg acttcattat tatgaaaacc aagaaccttg
     3541 gtagtggaga gttcacggat tctctcagct acgttgatat tggtcagatt gtaaaggatg
     3601 acaatagcta atagaaccga tacgatgacc aagatggtca tggtctgatt gagtgagcta
     3661 gcgacagagt cgaagagtcg aatggctgaa gcattttgga caacgctgga caccgcagat
     3721 tgactcataa gcaagcccgc ctgactttcg atactagttg cactggtatc ccttaatgag
     3781 accagataag tgttggcttg gggtagctgt ccgtaaagtt gctcatagct agcctgactc
     3841 atataaataa agtgaccaac gtagttctca gtaatagcag cgacctttag ttccttacct
     3901 tcaatttcta aagtctgccc aaccttgaca cctgccagct gggcgagttt agctgtaata
     3961 acgatgccat cttttaatgt cagctcctgc tgatgatgtt gaagatggat aaagggagtc
     4021 aaatcttcct tctctatcat cataagagta atgttttgaa gaccagcctt gcctttgaaa
     4081 tccttgtcta gcgttttaga atagattttc tggtaggcta gtatctcctg ccctttcaac
     4141 acttctgcta gctctacctt gtcctgatcg gtcgcactag gattttcaga gacaagcatc
     4201 tgatactgtt ggatttgttg aaactgttta gacggaactc ctgctacaga agattggatt
     4261 cccaaacctg caaagagcag agctacagaa cctgccacac caaagattgt catcaacatt
     4321 ctctgcttat aacgaaagat gttgcgggct gttaccttat gagtaaaact gagacgacgc
     4381 cagataaaac cgatacgctc caataagatt ttagctcctt tgacaggagg tttaggaagt
     4441 agaagctggg ctgcttcggc atgaagttcc ctccaagcca ccagataggc tggtaacaca
     4501 ctcgccaacc agctcaagac aagagctagt aagctatagg tccaatagaa ctgaatctgg
     4561 gtttctccca ccaccatgcc ttttgtaatg acacttgaaa ttacactggc tagcaaataa
     4621 tgaccaagta tactacctag agccgttccg acagtcccag ctactagtcc ataaaggaga
     4681 aacttggcga taatatcctt actacggtaa cccaaggcct taaaaatccc tgcatgagtt
     4741 cgctcttcgt ctacaaagcg agtcatggtc gtaaaggtca ccatggctgc tacggcataa
     4801 agtaccacag gaaagatatt gcccactgct cgaatactgg atgaagcatt gctatacata
     4861 agatagccct gaccacctgg catggtctga cgattataga cctgatacct tggctccgcc
     4921 aaatcgtcca agacttgctg atgtttttct aatttttcct tttcttgggc tagattttgt
     4981 tcagcttgct ttagtttgtc ttcttccttg cccaattcct gcttggcttg ggtaagttga
     5041 gcactagcct gctctctctg aacttgagga aacaaggcta gttgactttc ttgagcctgt
     5101 atacgagctt gagcagctgc taaacgacgc ttgccttcct gcaaattagt ctgagccttg
     5161 tcaagggtct cttgcccctt gtctagagac tcttgtcctt cttttttcaa aagttgcaga
     5221 cgtaccttgc cattatctga taaagtttgt tcaaggtctt cctgatgttg cttggatttt
     5281 tcttcataag ctgatgaaaa ggcatttaaa cctgctaaat cttgatattt caaacgagct
     5341 atattgtaga ctttctgatc aaactgacta ggtaaaatca ccccataggc tgtcagagtc
     5401 ccacttccac ttcctgcgta gcccatatct cgctgggaga ggatttcagc cgaatccaca
     5461 aaaccagtaa tggtataagt atggtctttt aaagaggaat gaccctcttc tttttcttta
     5521 aaactaatct cctgtcccac gctgcattgg ccttgcaaat gagtggccaa agcgatttcc
     5581 ttgtctgact gaggaagtcg tccctttctt agctgaaagg ttgaaattcg ctctggtttg
     5641 gagtacagcc gaatggcatc ctgcccatta tccatagtca catctgtcaa atagccaaac
     5701 tcgacctctg cgccctccgt ctgttttagt tcttcttggt ctgcttgatc caagccatag
     5761 ttagacatga ctgccaaatc caaggtttga gcagttgtta aataagcatt agctgtcgcc
     5821 tccatgttgg gactggttac tttgaggcct actaaggcta gagatcccaa catcatcagg
     5881 atcaagatgg ataaaaaacg ccccttggag cctgtgaagg actgaattaa gtccttccaa
     5941 taagtttttc gcttgatcat actagtactc caaactgtca atatcctgag gatgctggtt
     6001 gagcaccaca tccttgacac tggcatcgtg catatgaatc acgcgatcag caatgggcgc
     6061 caaagctcca ttatgagtca cgatgatcac cgtcgctccc ttttgacgag acatatcttg
     6121 gagaattttc aaaacctgct tgcccgtctg ataatccaag gctccagtag gttcatcaca
     6181 aagaagaatt ttaggatttt tggctaccgc gcgtgcaatg gagactcgct gttgctcccc
     6241 tccagaaagc tgggctggaa agttatttag acgatgagcc agacctacat ctgtcaagac
     6301 ctgatcagga ttcaagacat ctgtcacaat ttcagaagcc agttccacat tttccttagc
     6361 tgtcagatta gaaactagat tataaaactg aaaaacaaac cccacatcat ttctacggta
     6421 attggtgcgc tggtgggaac tataatccgc aatattaaca ccatcaatcc agatttcccc
     6481 ttcatcattg gtatccattc ccccaagaag gttaagcact gttgacttgc ctgcacctga
     6541 agcaccaagg ataataacca gctccccctt ttcaatctca aaattcacat cacgattggc
     6601 cacaatctcc gtgtccccaa cctgataacg cttgtaacag tgtttcatct caatataagc
     6661 catcagaccc accctctatc aaacaaatta tactcctcga aaatctctct tcaaaccacg
     6721 tcagcttcca tctgcaacct caaaacactg ttttgagcaa cctgcggcta gcttccttgt
     6781 ttgtgctctt tgattttcat tgagtattac ttcctattat cattataacg ctttttcaac
     6841 tagttgaaaa ctgcttatat tcttaaatcc ttattaaaag gcagtttcaa attactgcct
     6901 tataacatct tcttaaaaat aaaattgaac aagatcacct tctgctgttg ccaccgaaat
     6961 acaatctttc cccatgcatt tcgcttttat tttttcttga ttcattttaa tcacactctt
     7021 ctcaatatct ggataagaaa ctcgcaaatc tcctccactc cttgataaaa tggtcaactg
     7081 taagagtttt ttatcttccc agctcatgct cacttcaaaa tgtccacgtg ccattaagcc
     7141 tgaaacagaa cctgttgacc aagcatcagg tagggcagct agaggtacca gataagctgc
     7201 atgagactgg agtaacattt ctgccatgcc actagtagca ccaaaattac catctatctg
     7261 aaaaggagga tggctacacc aaagatttgg caaggtggat gtctttaact gctctgccaa
     7321 taatttatgg gctcgattgc catctcccaa acgcgcccag agattgatct tattagcctt
     7381 ggaccagcct gtgccgccat ctccacgatc attgaggcta gcacgcgccg cttcaatata
     7441 ctcttgtccc ttgtagctaa agagattgcc aggatagagt cccactagat gggaagcgtg
     7501 ccgatgctgg gcctccactt tctcattttg aaaatactgc tcttcctcct cataccactc
     7561 cctgattcga ccagattgag tgatttgcaa aggatttagt aaatcagact tctccttaac
     7621 ctcagtcaac aagtcctcat ccagtcccaa ttcctgagca gcctgaataa aatcatgaaa
     7681 taactgccaa attagagatt ggtcataagt attgccaatc gaaatcggcc catgttctgg
     7741 ggaataagac ggagaagaca cccaacgctg cgcctgctga tccttatgta aaaaggcatt
     7801 ccaaaaacga accgtttccc tcaacatggg ataaattttc tccctgagat agtcttggtc
     7861 cctataaaat gaataggctt cataaacggt ttgcatcatc cacgcattgg cagctggtga
     7921 ccaaccccaa tagtaatccc aaccaggtgc cgtccaacca aagggagtcg cttgagtatg
     7981 aaccaaccaa ccattttcct cacctttttg agagacgatt cctgcatact ttacagccgc
     8041 tagacgacca tagacacgca aatcatctac atagttgatg accggaaaga ccgcctctag
     8101 gagattggta acataggctg gccaataatt catctgcaga ttgacattta agtgatagtc
     8161 cgaattccaa ggaggattgt cgaccgcatt ccagactccc tgtaggttag ctggtagagc
     8221 atctgggcag tctctggacg aactaatcaa taaataccgt ccatactgga agaacagctc
     8281 ctccaaagcc tgcccttctt gtggcttata attttttaac aaatcatctg tagtgaatgc
     8341 gtcaacatta gcttccaaat ccaattgaac acgctggaat aaggcttggt agtcctcgat
     8401 atgccttgat ttcaattggg tatagccctt ttctttagct gtgtccacca agtctatcac
     8461 ctgttgctct aaatctagtt tcttgcgata attgctagca ggattttggg caaaatccgt
     8521 cttagcggcc aagaagagat tggcataact ggctcctgat atctgaaccc tatctgacca
     8581 aactctaata tctccatccg tttcccaagc tagataacta gcaaaccgca gatcattatc
     8641 cttaactctt cccttcatca agatatgaga atcagtaata tccaacttac actccttgta
     8701 atcagatttt tcctgctcat actttccatc agaagccaaa tcacaggtca aggatagttc
     8761 tatagtaaaa tctagagttt ccgccccttc cttagtaaaa cgctgaacca agagatcatc
     8821 tggaaaactc gcaaaagctt cacgttcaaa tcgcgttccc ttatagacat aagaagtcgt
     8881 cacaagtgcc ttactaatat tcagctgtct ctgatagtcc gtcacctgag acaaagtcgt
     8941 accttgctgg ctgaactcaa tgtgaatatc cccaaaagac agataggtcc catattgact
     9001 cgtttttggc ccaattaggt gctgctcagc cagttcctta gccagattgt aatctctctt
     9061 ctccaaagcc tgccgaatct cagctaaaaa aacatactga tcctgaagat ttccaccctg
     9121 ataatctgaa ctatcaggaa gtggacctcc agaccagaga cttttttcat taaattgaat
     9181 ccgttcagcc cctataaggc caaatacttt tgctcctaaa gaaccattgc ctatcggtaa
     9241 agcttcttct tcccaaccca tgtaagtggt tgaaactggt tgcttgtagg ccagtacata
     9301 atcttgtttt ttattcctta tcatacttcc atactaacat aaaaagccta gaaatcaatt
     9361 ctagacttac aattttttat tttccaaggt agtattcaga aacgacgttc aatttttcgt
     9421 cgaattcgaa taccaatggt gggaagttag ggatttccac gtccatgatc tcgtcatctg
     9481 acaaaccttt gatgtgtttt acaagggcac ggattgagtt accgtgagct cctacgaata
     9541 cgtttttacc atctttaaga gctggagcga ttttatcttc ccagaatgga agagcacgtt
     9601 ccaaagtcac tttcaagttt tcagcatctg ggataactga gtcgtcaagt gaagcgtaac
     9661 gacggtctgt gtgagctgag tgctcatcat cacggtccat gtttggaggc aatacatcgt
     9721 atgaacgacg ccagatgtga acttgctcat caccaaattg ttcagcagct tcagctttgt
     9781 ttttaccagt caaaccaccg tagtgacgtt cgttcaagcg ccatgatttt tcaactggaa
     9841 cccacaattg gtcagaagct tcaagagcca agttagttgt tttgatagca cgtttcaata
     9901 ctgaagtgta agcttggtca aattcgatac cagcttcttt gatcaattta ccagcgtcaa
     9961 tcgcttgttg tgtacctttt tcagacaaat caacatcagc ccaaccagtg aaaaggttag
    10021 ctttgttcca ttcagactca ccgtggcgag caaaaaccaa ttttaccatt agatggattc
    10081 tcctttaaat tttccgaggt ttcccctcgt ttatctattc tattttacac aatttttcac
    10141 aaaaaagcta gtcaaaacca aaaaggaaag gactgtttga caatgtttgg caatcacatt
    10201 gtttttggct gtttctattc tatcttcatt atttaacctt tttttctgcg catcgaataa
    10261 tttttgagtt gactctttta gtttagtaaa cgagtcatta ttttccatag ctgtgccttt
    10321 gaaaccttcc tcagctttag taaaataatc atcaaaaata tttttataaa gatctatata
    10381 atctgcataa gtgcgtattg attcaatcac atcgtctgtt acaaccggta tatcgaaagt
    10441 gattgtttct tttgaactat tggatgttgc tactgtcttc tcatcattac ttgttgaagt
    10501 atcctttgaa ctttatgttc cacatgcaac tagaagaaaa agagataata gagctactcc
    10561 tataccgata aacttttttg ttcttttcat gctaaaatac cttttattct tctgatttga
    10621 atttcttcaa tgttgcaagg aatagagatc ctccgataat aacaagaatc cccccaaccc
    10681 atcctaagaa tggaatgaga ctaactccac caaaaacaat cattagtaca gacggagctg
    10741 cacctacacg attatctcct ttatagtaaa caatagcaat gataccaaga acaagatttg
    10801 caatcttcaa ggcattcaag agtaaggcaa cacctgaaaa agcccctgca gtagctcctc
    10861 cattaagagt tgtagcaact gtgtttaccg ctgttcccaa caagacaaaa ggaccaataa
    10921 gaagtaaaat tcctcccaca agaccgacga taccactaat taaagcaagt g
//
LOCUS       DAVMAH010000060        10613 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVMAH010000060 DAVMAH010000000
VERSION     DAVMAH010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.060"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(<1..416)
                     /locus_tag="VYO94_001760"
     CDS             complement(<1..416)
                     /locus_tag="VYO94_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760352.1"
                     /translation="MMRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIF"
     gene            complement(422..739)
                     /locus_tag="VYO94_001761"
     CDS             complement(422..739)
                     /locus_tag="VYO94_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760353.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGDWNTFKNNIKGLARASSGFRF
                     AARETGLWAAIWSTRVYSYTYVVSAFAPILGSVAAVNAALAVIGGISVAGITYALWTR
                     KFY"
     gene            complement(884..2236)
                     /locus_tag="VYO94_001762"
     CDS             complement(884..2236)
                     /locus_tag="VYO94_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HEV1760354.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLEKLRAKEAIFQKFEQSLNEKYNHLSNSGEEQEYYGKVEYYLSQLNSENYNN
                     GTQYSKIQDEYTKLNKITAERNQLDADLQALQNELLQLQQQGDSPSLSDTTSADNKAK
                     LETKISEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLVSEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILAPNEGTLHYLLPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKADVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVVLQKDMPVEVRIVYDKETYLDWILEMLSFKQ
                     "
     gene            complement(2233..2700)
                     /locus_tag="VYO94_001763"
     CDS             complement(2233..2700)
                     /locus_tag="VYO94_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1760355.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(2693..4912)
                     /locus_tag="VYO94_001764"
     CDS             complement(2693..4912)
                     /locus_tag="VYO94_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEV1760356.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDITLSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIMDKTTIVVAHRLSTILR
                     CDKICFLENGTIMEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDTEEVTYG"
     gene            5378..6241
                     /locus_tag="VYO94_001765"
     CDS             5378..6241
                     /locus_tag="VYO94_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1760357.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILSHLKK
                     EVEIYYQAKER"
     gene            complement(6530..7318)
                     /gene="argH"
                     /locus_tag="VYO94_001766"
                     /pseudo
     CDS             complement(6530..7318)
                     /gene="argH"
                     /locus_tag="VYO94_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
     gene            complement(7378..8574)
                     /locus_tag="VYO94_001767"
     CDS             complement(7378..8574)
                     /locus_tag="VYO94_001767"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV1760358.1"
                     /translation="MSKEKVILAYSGGLDTSVAITWLKKDYDVVAVCMDVGEGKDLDF
                     IHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKYPLVSALSRPLISKKLVE
                     IAHQTGATTIAHGCTGKGNDQVRFEVSIAALDLNLKVIAPVREWKWSREEEIYYAKEN
                     GVPVPADLDNPYSVDQNLWGRANECGILENPWNQAPEEAFGITTSPEQAPDMPEYIEI
                     EFSEGVPVSLNGEVLKLADLIQKLNEIAGKHGVGRIDHVENRLVGIKSREIYECPGAV
                     TLLTAHKEIEDLTLVREVAHFKPIIENELSNLIYNALWFSSATQALIAYIKETQKVVN
                     GTAKVKLYKGSAQVVARKSPNSLYDENLATYTSADTVDQDAAVGFIKLWGLPTKVHSE
                     VQKSAK"
     gene            complement(8591..9397)
                     /locus_tag="VYO94_001768"
     CDS             complement(8591..9397)
                     /locus_tag="VYO94_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1760359.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            9608..>10613
                     /locus_tag="VYO94_001769"
     CDS             9608..>10613
                     /locus_tag="VYO94_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEV1760360.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDLSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGL
                     I"
BASE COUNT         3360 a         2215 c         1610 g         3428 t
ORIGIN      
        1 aaaaatattg tagtaagcat gatgattgca aaaggaattt ttaaaataaa tactaggata
       61 atagcaattt caagaataaa actccatata atcctagatc ttaaatcatc aggcgacaaa
      121 cttttacgat ggaatgaaaa atagggcgag aacctcacat ttactttctt cctgcctata
      181 aaaataaaag gaaaaatcgt aataagagct tctttcttgt acaaatcttt caatgcgtat
      241 agtatgtcta aaactatttt tgataaaatc aaactacaga aagcaagact catactaatc
      301 acaaaatcaa ggggagattc tagattcaat agtaagttat tcactaggac atgcaactct
      361 agccacaaga caaaaagagg gagcattagt aagaaaacaa ttagtttacg cattataaca
      421 attagtaaaa tttacgcgtc cataaagcat acgtaattcc tgcaactgaa atacctccaa
      481 ttacagccaa tgccgcatta acagctgcta ctgaccctag tattggagcg aaagcagaaa
      541 caacataagt ataagaatac actcttgtag accatattgc agcccataaa ccagtttctc
      601 ttgcggcaaa cctaaatcct gaggaagctc tcgctaaacc ttttatatta tttttaaatg
      661 tgttccagtc tcccccatca aggtacatca tctcttcttc atcaatcaca acataattat
      721 ttggtaatac aagttccatt tgttttctcc tttttattaa gcatggttag gatggtttcc
      781 taacaagtaa tcgtcgtctg cgtttctatc acttagctac ctagataaga tatcctttct
      841 ctaccttatt tgtttttata ggttacctaa ggtttaaaac caattattgc ttgaaactta
      901 acatttctaa aatccaatca agataggttt ctttatcata gacaatccgc acttcaactg
      961 gcatatcctt ttggaggacg actgtctcac ttccatgttt tagagttaag gtttctaatt
     1021 ctatcatgac tttataaaga ctaatattgc cttctttcgt ttcttgggaa attgttcctg
     1081 aatcaatctg tctgacttgt ccctttagtg ttccatattt ttgactattt acaccagtaa
     1141 tagcaacatc agcttttgct cctttcgaaa cacgagaaat atcactcgca agtacaaaag
     1201 cttctacata gtaacctttt tctttccctg aaacttctgc tatcgtttgc ccctgctgaa
     1261 tagacattcc ttgtttcaaa ggtaacagat aatgcagagt accttcattt ggcgctaata
     1321 tactatgagc tttatcttga cctgttgcca ctccaagatt agcctcaagc tctgtaatac
     1381 ttttattgtt gtttgaacga gcagtaccta actcactaac taattgagca taaatattat
     1441 aagcctgaga agttggatca ttataggtac ggttcatatc cttaatattg ctttgttgac
     1501 tatcaatctc gctattctta gaagtaatat ttgtttttaa tgcttcgatt tttgttgtta
     1561 tttctgatat cttagtttct aacttagctt tgttatcagc tgatgtcgta tctgatagag
     1621 aaggtgagtc tccttgctgt tgaagttgaa gcaattcatt ttgtagagct tgcaagtcgg
     1681 catctaactg atttctttca gctgttattt tattcaactt cgtatattca tcctgaatct
     1741 ttgaatactg ggtaccatta ttataatttt ccgagtttaa ctgagacaga tagtattcaa
     1801 ctttcccata atattcctgt tcttcaccag aattagataa atgattgtat ttctcattta
     1861 atgattgttc aaatttttga aagatagctt cttttgcacg taacttctcc aattgtttat
     1921 ttaaagagct cgcttgtaaa ccttcttgtc cacttgataa cgaaataatg acatctccag
     1981 catttaccat atctccttct gacttatgta aagtaactac cttccctgaa ccaattgctg
     2041 ataggaactc tgtacctgtt ataactgaat ttccattcgc ttttacaata tagtttttgg
     2101 gtatataagc tgcgccaacc aatgcaccgc ttaagataat agcagttgaa ataatgagaa
     2161 taaacgcaaa agctggtggt ctcttatcaa agaaaatacg agaataacgt aattctgatt
     2221 tattatataa tttcataggc ttacaattgg tctaaaaata tctactacca ttttttcagg
     2281 agaagaatta acataaactg tatagacaat cccatccgtt tgaatatcat tttcatagac
     2341 atatagatcc aatttagaat acgcatactg tagatactct ggactgtctt caaaacgaac
     2401 atataaacaa tatggaacag agatagaatc ctgtacatca taaatgttac tgtactgttg
     2461 agcattatga gcttgaatat aaaactcaaa atcagtcgtt attaatccat catcatgaat
     2521 agtagtacca caacttttta caattaatgg accaaaaatt tgtgctttta acaactgcaa
     2581 atgttgatga aatttattaa tttcctgatc tacatcttct acttttgtat catgtaactt
     2641 tttacagata actgacttta gtaccagttt tttattatct tttacctcta acttagccat
     2701 aagtaacctc ctctgtatct aacacagcct gtgactgaat ttgttgattc acttgaacgc
     2761 tctgcaaacc aaccattcta gcatactttc catttttcgc cattagttct tcatgagtac
     2821 catattccat aatagtccca ttttctaaaa agcatatctt atcacatcga agaattgtag
     2881 acagcctgtg ggctactaca attgttgtct tatccattat tttattaaag attaaatcct
     2941 gaataatctg ttcactaaat gaatctaagt tagaggttgc ctcatcaaat atatacaaat
     3001 cagctttact cagtagtgct cttgcaatag ccaatcgttg tttctctcca cccgagaaat
     3061 tttgaccgcc ttcttctaca aaggagccat aacgattttg aagacgttga atcgtatcat
     3121 gaataccaac aatacgacaa actctcacca tatcctcata tgtaacagaa ggattaccaa
     3181 tttttagatt atcaataatt gtccctgtaa agagttctat ggtctgagga atgtaggaaa
     3241 ttttcttacg tagtttacca tagtcaagat ctgataagtc attttctcct atacgaattt
     3301 tcccctcact cggatttata aatcttaata acaaacgaac tagcgtactt tttcctgctc
     3361 cgctttctcc aacaaaagct attttttctc cttgtttaat tcgcaaatta aagtccttga
     3421 taacaggagg gcgtgaacca taggcaaatg ttacatcttt aaattcaatg tcatcacata
     3481 aggtgaagtc tctaatacta taatccaagg caatgtcttc acgatctact tccatcaatt
     3541 cttgaagccg actaaccgca acctgtacct cttgaaaggt taactgcaag ccaactaaat
     3601 tctgaatagg ttctgtaaaa tattgactta atgtctgaaa aaccaagagg tccccaatag
     3661 tcatttttcc atcaatgata aataaggcgc ccactcccat aaataataac ccacccatgg
     3721 ttgaggtcat tgaagatatt gtagattgaa tattctgcaa aacaccctct ttataaccaa
     3781 tttctaaagt atgaacaaat ttttcttcaa ttttgtttaa acgttgttcc tcatcatgct
     3841 gagacttaat ggtatcaatg ttacgaatag attcaattaa ctgtgaatta agaagtccat
     3901 ttgcttccat ttgttcatga ttaatttttt tataaggctt tttaaaacag tatataagaa
     3961 tgatgttaac aataaccata aaaactaata tcagaaataa agattgatta atagtccaaa
     4021 ggacaaccgc actaataact gacaaggtga tatccatgac taatgaaata gagactgacg
     4081 taaacacatt ctttatcgtc atcgcatctt gaaatcttgt taaaacatca ccaactctac
     4141 gacttccaaa aaaactataa ggaagatgaa taatatggtc ataatatccc attaaaaccg
     4201 gtatatcaat ttttcgagat agaaacaaaa gaacgtgctg acgaaatgca gatagaagag
     4261 tctgtaagaa cgacactatt ccaaatacta tcaaaaacat atacagacta ttttttaaag
     4321 catatggaat cacctcgtcc atgataactt ttgaaaagag actcgataaa ataccaatga
     4381 tacttaaaac aaaggaagct aatatgactg tactaatcaa tcctttttga ttaaaaatta
     4441 accttccaaa taaatcaaga agtccttttc cctttagttt ccctctttca aaatccgaat
     4501 ttggaaccat aaaaagagta ataccttgat aaatttctcc cagttcgtca cttgacatct
     4561 tgcgtatgcc actagcaggg tctgctacgt agaacttact attccttttg atactatgta
     4621 gtaccacaaa atgattttga cctaaatcat tcttaacttg aagaatcgca ggaaatgtta
     4681 attttggagt caaatcttcc agtgctactc gaacagcttt tactgtaaaa ttcaacttat
     4741 tcagacctga aacaatacca ctgacagtcg ttccatacat gtctgtacca ataatttccc
     4801 taatcttcat gattgatagt tcctttttgt aagataaaag aactgttgaa acaactgccg
     4861 cagcacaatc tgactggtca tgttgcatcg tacaaggata tttttttaac atagaaatac
     4921 tcaattcttt agaattaatc taacttttct ttgatgtcac ccaaacctca atcactgccc
     4981 agtagttctt gaattaattt attttcaacc gtatcattct ttgttcttga tatctttcca
     5041 agcattgtag tacagcagat ttttgcccaa ggactgagcc tcctttaaca actcaaactc
     5101 ccttacatta tatcggccag ccccatggaa agattatagc cagactaatc aatgatataa
     5161 tacatactag aatacaaaat atttttttat tcatactttt tctcctatct ttattttcta
     5221 cctacatagt acctcttatt aagctcattt taaaattacg ttaacttttt tcacaaattt
     5281 atttcgactt tcttttttac tttttacatt gctatgatac aatattttta acaaaatttt
     5341 attgtttgtt aacttttttc acgaaaagga gaaaatcatg cgttatgatt tcggaaaggt
     5401 ctataaagaa atacgtgagt caaaggggct gacccaagaa gaggtctgtg ggggtgttct
     5461 ctcaagaacc agcttatcaa aaatcgaaag tggcaagaca accccaaaat atgaaaatat
     5521 ggaatttctt ctccgtcaaa tcaatatgag ttttgaagag tttgaatata tctgtcaact
     5581 ttatcaacca agtcaacgca cagagattat gcaaacctat ctcaatatgc gttccattat
     5641 cgggaccagc gatcttgtca atttatttca aaaatgccaa gactacctca agacccacca
     5701 cgatctccct atagaagaaa tcagagatat gcttgaagtt gttatttatc tccgtcaaca
     5761 cggggcaggg gaactatcaa aacacgcaga acaggttgtc aaaaaacttt ggaaaaaaat
     5821 tgaaaaacaa gatacatggt atgagagtga tctaaaaatc ctcaatacca ttcttttcag
     5881 ttttcccatt gaatacctcc atctcatcac tggaaaaata ttgcaacgcc tagaagtcta
     5941 taaaaactat caacatttat atgacttgcg aatgacaatt ctattaaacc tttccacact
     6001 ctatctatac aatcaagata aaaacatgtg taagcaaatc tgctacactt tactggagga
     6061 cgccaagaat aagaaaagct acgataggct ggctatctgc tatgtccgta ttgggatttg
     6121 tagggatgat gcgaaactta tccaaaaagg gttctccctt ctggagctaa ccgaggaaac
     6181 ttctatactg tctcatctca aaaaagaagt agagatctat taccaagcga aggaaagata
     6241 aaaaagccga gggatttcct cgactcttta catattattt gttcgttagt tcttaatacc
     6301 agccattgtt aagccagaag tttttagctc tgccaagcca catagtgtgt ttactactat
     6361 gtgtccatgt caccatgaat cgccgaacga tttaacgaga aagtatgact tttacgttta
     6421 tcccaactca attatgacat ttttttcaaa agtcaatata tctcactttt tcaacgacaa
     6481 gaaagaggct gccaatcgac caacctctta ttctgaaccc atcactccat cactttttag
     6541 cttcattcgc tttcttagcg actgcaatct ggtattcgac ttggtcaaac cctgtgcctc
     6601 ccaaggaatt tcgtctttga acagcagttt taggttgcaa gtagacatag atatcctcgg
     6661 taatgagaga atgataggtt tgtaattcct ccaaagtcca atcttgaaga tttttagcag
     6721 acttgataga gtctagcact aatcttccca caacctcatg agcttctcta aatggcaagc
     6781 ctttccctgc caaataatct gccaactcag ttgcatttga aaagtccttc tctgttgatt
     6841 cttgcatttt ttccttgttt acctgcaaac tagataacat acctgccaac acatcgaggg
     6901 aatttaaaat cgtttcgacc gtatcaaaca ttccttcctt atcttcttgc aaatccttat
     6961 tataagctaa aggcaaggac ttcatgactg tcaacagtcc aaacaaatgc ccataaactc
     7021 tgccagtctt tcctcgaatc aactcagcca tatctggatt tttcttttgg ggcataatag
     7081 aggaacctgt tgtaaacgta tctgacaagg taatgaattg gtactcaaaa ctacaccaat
     7141 tgatcatttc ttcgcaaaaa cgactcatat gcatcatgag tatgctggca tttgatagaa
     7201 attctaagat aaaatcgcgg tcactaacag catccaaaga atttgtataa ggttgcttaa
     7261 actccagcaa atcgctagac aattggcgat caatggggaa agtcgttcct gccaaagcga
     7321 ccaccccata attttgtatt cttagccata tcacatccac ctctctatcc aatcgtccta
     7381 tttggcgctt ttttgaacct cagaatgaac cttggttgga agtccccata acttaataaa
     7441 gccaacagcc gcatcttggt caacggtatc tgcactagta tacgtcgcca aattttcatc
     7501 gtaaagagaa tttggtgatt tccgagccac gacctgagcg ctccccttat acagtttgac
     7561 ttttgcagtc ccattgacaa ctttttgagt ctctttaata taagcaatca aggcttgtgt
     7621 agccgaacta aaccacaaag cattataaat gagatttgat aattcatttt ctatgattgg
     7681 tttaaaatga gccacttctc tcacaagcgt caagtcctca atttccttat gagctgtcag
     7741 cagggtcact gcacctggac actcatagat ttctcttgat ttaatcccaa ccaagcgatt
     7801 ttccacgtgg tcaatccgtc caaccccatg ttttccagct atttcattga gtttttgaat
     7861 caaatctgcc aattttaaca cttctccatt gagggaaact ggaacacctt cactaaactc
     7921 aatctcaatg tattctggca tatctggagc ttgctctgga gaagttgtga tgccaaaggc
     7981 ttcttctgga gcctgattcc atggattttc caaaatacca cactcattgg cacgtcccca
     8041 aagattttgg tcgacagagt agggattgtc aaggtcagca ggaacaggca ccccattttc
     8101 cttggcataa taaatttctt cctcccgaga ccatttccat tcacgaactg gagcaatcac
     8161 ttttaaattg agatccaagg ctgcaatcga tacttcaaaa cgtacttggt cattcccctt
     8221 acctgtacaa ccatgagcaa ttgtagtcgc tcctgtctga tgcgctattt caaccaattt
     8281 tttagaaata agagggcggc tcaaggcaga taccaagggg tacttttgtt catagtaggc
     8341 atgtgactgg agagctacta gcacataatc tgtagcaaat tcgtccttaa catcaatgac
     8401 ataagattcg actgccccaa ccttaagagc cttatcatgg atgaaatcta agtctttccc
     8461 ttcacccaca tccatacaaa ctgcaacaac atcatagtct ttcttcagcc aggtaatagc
     8521 aactgatgtg tctaaaccgc cagaataggc caaaattact ttttctttac tcatgttctt
     8581 ttccttcttt ctatttttca atggacgctt taaaggcatc ctcaatgagt ttgtctaatt
     8641 ccccagactc cttcaacttt tgaatggttt tatcgactgc ctctttcaat tccttgctat
     8701 cttttttcat ggctaccgca taggaatcat cttgctcttt ttcaaaattg aggtctgcga
     8761 ttgctaaatc aggattattt tccacaaatc ccttggcaac gggttcttca aaaataacgg
     8821 catccacttg ccctgatttt aaatctgtga ttaaattccc atttttaggc agagatacga
     8881 gggaagaatt ttgtagcaaa tctttcgcca tcgtctcttg aatcgaacct ttctgcgctc
     8941 cgaccttttt ctgcgccaaa tcgttgacag actgataagt ggctaaatca gattttttga
     9001 caatgagttt attttttgca gtatagtagg gagttgaaaa atcaaacacc ttgctccgtt
     9061 catctgtctt agaaacacct gatatggcaa ggtcagcttt tcctgattga acgctagcca
     9121 gtacattgtc aaaactcata ggagatagtt ccaattcgac acctagttct gttgcgatag
     9181 ccttggctaa ttcgatatct gaacccacaa tctgattttt cccatcaacc actttttgat
     9241 attcaaatgg agcaaaatct ggattgaggg ctacaaccaa ttttcctttg gacttgatgg
     9301 cttcaattcc agccgattga ttgttactac aagcaaatag tagggggagc atcactaaac
     9361 caaacatcgt catcaacacc ttcttcatct tattcataac aaagcctcct ttatgtttat
     9421 tcttttttat tgtataaata atactcctat actcatcctt tgtcaagcct aaattgaaaa
     9481 aattggctct ataatatttg tagtgggtaa atcccctata gatattatgg agcctatttt
     9541 attgtagaaa aaaagtccca tatgacctat aatgaaaagc gacaaaacca tcattagaaa
     9601 gattcatatg gaacaattac attttatcac aaaactgctc gatattaaag acccaaacat
     9661 caagattcta gatatcatca atatggatac ccacaaagaa attatcgcta agctggatta
     9721 tgaggctcca tcttgccctg attgtggaag tctaatgaag aaatatgact ttcaaaaacc
     9781 gtctaagatc ccttacctcg aaacaactgg tatgccttct agaattctcc ttagaaaacg
     9841 ccgtttcaag tgctatcact gttcaaaaat gatggttgct gagactcccc tggtaaagaa
     9901 aaatcaccaa atccctcgta tcatcaacca aaaaattgct caaaagttaa ttgaaaaaat
     9961 ttctatgact gatattgccc atcagctggc catttcaact tcaactgtca ttcgcaagct
    10021 caatgacttc cactttgagc atgatctttc tcggcttcca aagattatgt cttgggatga
    10081 gtatgccttc actaagggaa agatgagttt cattgcgcaa gattttgata atcttaatat
    10141 tatcactgtt cttgaaggca gaacacaagc tgtcatccga aatcactttc ttcgctacga
    10201 tagagccgtt cgttgtcaag tgaaaatcat tacgatggat atgtttagtc cttactatga
    10261 cttggctaaa cagctttttc cgtgtgctaa aatcgttcta gatcgtttcc atattatcca
    10321 acatctcagc cgtgccatga gtcgttttcg tgttcaaatt atgaatcagt ttgaacgaaa
    10381 atctcatgaa tacaaggcta tcaagcgtta ctggaaactc atccaacagg atagtcgtaa
    10441 actcagcgat aaacgttttt atcgccctac ttttcgcatg cacttaacaa ataaagaaat
    10501 tcttgacaag attttaagct attcagaaga cttgaaacac cactatcaga tctatcaact
    10561 cttacttttt cactttcaga acaaagaccc tgagaaattt ttcggactca ttg
//
LOCUS       DAVMAH010000061        10590 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVMAH010000061 DAVMAH010000000
VERSION     DAVMAH010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10590
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.061"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(105..1529)
                     /locus_tag="VYO94_001770"
     CDS             complement(105..1529)
                     /locus_tag="VYO94_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1760361.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQTMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2074..4353)
                     /gene="pulA"
                     /locus_tag="VYO94_001771"
     CDS             complement(2074..4353)
                     /gene="pulA"
                     /locus_tag="VYO94_001771"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV1760362.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDENG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4465..6423)
                     /gene="ligA"
                     /locus_tag="VYO94_001772"
     CDS             complement(4465..6423)
                     /gene="ligA"
                     /locus_tag="VYO94_001772"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV1760363.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6516..7694)
                     /locus_tag="VYO94_001773"
     CDS             complement(6516..7694)
                     /locus_tag="VYO94_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1760364.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7774..8637)
                     /locus_tag="VYO94_001774"
     CDS             complement(7774..8637)
                     /locus_tag="VYO94_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1760365.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYHSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8640..10541)
                     /locus_tag="VYO94_001775"
     CDS             complement(8640..10541)
                     /locus_tag="VYO94_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1760366.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVKIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3183 a         2337 c         1897 g         3173 t
ORIGIN      
        1 gtttcaatct attataatac caaaaagttc gtattttttc tataattatt attattttat
       61 agcaaaaaaa taaaaccagg aaaacaattt cctggtttta cacgttattt cacatcaaaa
      121 acaatggatt tgacatttgt catcgcttca atgctatatt taattccttg cactccagct
      181 ccagaacctt tgacaccaag gaatgggaaa ttatctggac cacgctgggt tttattatta
      241 atgtggactg tacctacttc aagtttttca gcaatttcaa aggctttttt gaaatcattt
      301 gtaaagactg atgattgaag gccgaattca gattcgttgg caaaggcaat agcttcctct
      361 acactagcca cacgaatgat tggtaaaaca ggaccaaatg gctcttccca tgccactttc
      421 atatcttttg taacttggtc aaaaagcact ggccagagaa gattgccctc acgtttgatt
      481 ggtgtaagag cctgagcttc tttttcttgt gcatcctcaa tcaagcccca aatgaagtcg
      541 gctgaagcat tgtcaataac aggtgtaata tcagcattgt caaatggatc accaactgtt
      601 aatttagaaa cttcttcctg aagcaaagta gctaatttat ctgctacact ttcgagaaca
      661 atgacacgtt taatggccgt gcaacgttgt cctgagtagc taaaggctcc cgcaacaatt
      721 tgcttggcag catgttccaa atctgcatct tctagtacaa gagctgcatc tttcccacca
      781 agttccaaca tgataggacg cataccagct aaacgaccaa tacgttctcc aataggagtt
      841 gaacctgtaa agttgatgaa gttgacttct ttgtgctcaa tgatataatc cccaatttct
      901 gaaccacgac ctgtaatggt gttgaaaaca cctgccggaa tccctgcttc ttcaaatgct
      961 ttagccaaca agagtccaga aatggaacct tgtgttggtg gcttaaacat gaccacattc
     1021 cctgcaatca aggcaggtgc aattttagaa gcagataaat taactggata attaaaggga
     1081 gcaatcgcta gcacgatacc aactggttca cgacggacaa cagccagttt gtttttactt
     1141 gctgcctcaa aaccaccacc ttccattgtt tgtccagtga tacggagacc ttcctcagca
     1201 gcataacgaa tcaagtctgc tgtacgcact acttctccaa ttgctgcttt aatccctttt
     1261 gctacttctt tggcaaggat agtaccaatt tcttccttat cgcgttctaa aatagctgct
     1321 gttttatgta aataagccgc acgttcaact gctgataaag ctcgccatgc tggcagggct
     1381 gcacgcgcag cttgcatagc ctcatcagct tcagtctgag tcatggctgg aactgtaccc
     1441 aattcttctt gattgattgg tgaataaatc gtaatttctt gttcagatga tttccatttt
     1501 ccatttacta aattctgata tcttgtcaaa ttcttgtcct cctgaaaatg attaagatat
     1561 attttaccaa attttcagaa aatcacaacc ctttttgcaa aatttttgag attattttca
     1621 caaacttgat ttttcaaagt atactcaata aaaataaaaa aaatccacta cgtcaaggcg
     1681 aggctaatgt ggtttgaaga aattttcgaa gagcgtgaat gagtatcatc tatagtaaaa
     1741 taaaaaaact gaacaatttg gttggggaca gccaaaccaa tttctcacaa tgtttcagaa
     1801 acaagggtgt gctactccaa tttcagccta ctataactgt catagattgc tgaaacaaag
     1861 tctaggtaaa agtcttcata ataaaaagac ctcctatcaa gtgttcaaaa actttgatag
     1921 gaggtcttgt tttgtgaaaa tatttatcaa attttctata caagtgagct gttagccagg
     1981 ttctttctat tctttcaatt tcaatgaatg gattttttac taatactcat aactgggaat
     2041 ttgtctgtgt aaaaatagcg agatagatgg tatttataaa acactcaaga cagctagact
     2101 aatatcattt aaaacattat cttcttttga gcgactgttg gttaccaaca tagctaaatt
     2161 tcctgcattt tcaaattgat agggttctga tttagcattc acaaccacca agaggtgttc
     2221 tttgccgtga acttcataga taaggtagcc gctatgttca atcgcagaat gcacaaagac
     2281 atgatggtaa atttcatcat agctagagta agaaaaggca ccagtttttg tcttcaatcg
     2341 gatgacttga cggataaact caatactgtc ttgacgctca ttaatcaagt tccagttcac
     2401 ttggttcaca ctgtcaggag cattatagct attcatcgca cgctctctat catcatgggt
     2461 caactcacca ttttcaccag tcgcaaccag tttggtacga ccaaattctt gaccgatttc
     2521 cataaaggcc atcccctgca tgagcagatt catggctgtg gcagtttcga ccttgcgcat
     2581 gatttgctct gaactttggt ctggatgaag ggttgccaat aaatcgtgaa gattgtaatt
     2641 gtcatgggct tctacatagt taagcacctg atttggatgt gtatagcttc ctaattcacg
     2701 acttcctagg attgctttag ctagaattgg ctctgtcgca gcaccactga caaaacctga
     2761 cttgatagca ccataaactt ctcccccttt gacagcatcg cgctgattgt cattaaagaa
     2821 accaatattt ggcatctggt aggcattgtc cttcttggcc ttatcataag gggcaagacc
     2881 tgttcccata tcccatcctt ctccataaag gataatgttg gagtcgattt catccaagct
     2941 ttgacgaatc atctgcatgg tcttgacatc atgaatcccc atcaagtcaa aacggaagcc
     3001 gtcaatatta tattcctgca cccagtatag aagagaatca atcatatact tgcgaaacat
     3061 ttcgtgttca ctggctgttt catttccaac acccgttcca ttctggaagg taccatctgg
     3121 attcatacga taatagtaat cagggactgt tgtttggaat ggtgcatcaa caactgagaa
     3181 ggtatggtta tagactacat ccataatgac tccaataccc gcatcgtgat aagcttgaac
     3241 catcaccttc aaatcacgaa tgacctgagc tggatcatct ggattagttg aaaaactagt
     3301 ttctggcgcg ttatagtttt gtggatcata accccagttg taggttacat ttccattctc
     3361 atcgtattct ttatgacggt ctgcaattgg ttgcaattga acataattgt agcccagctt
     3421 cttgatgtaa tcaaaagcag ttgactggcc gtattggtta actgttccag cctgagcagc
     3481 acccaagaaa gttcctcgaa gatgttcatc tacacccgat gtaggtgatt tagtcaaatc
     3541 acgaatgtgc atttcacaga taactgcctt acatggattt tccaagcgcc aagtagcctc
     3601 cgaaccgtgc ttaacctcga agttttcaac ttgcttttct acatggctca gaatagctga
     3661 acgtttgcca tcagggctgg tcgcgattgt ataaggatca cgtgtcagtg tttggtgatg
     3721 agggaattgg acttgatact gataagtctt acctaccaaa tcttcttcaa catccaaact
     3781 ccagacaccg attgtattgt ccttatgatt ataagagtag ctattgcctc ttttcatctc
     3841 aaaagtcttc caaacgggtg catcattagc agctgattca taaacgacaa cttgcacttc
     3901 tgtcgctgta ggtgaccaga gagaaaaatg agcctgattg tcctctacac ggcaacccaa
     3961 ttctccttgg taaccccaat gatgatcaaa actagcactg ttaatggcct tatcaaaggc
     4021 aaaaggattt tgatttttat agaaaggact ggcaatagca ggattttcag agtaataaat
     4081 cctatcatcg ccttccaaaa tccagacctc tgttaatagg ggatagtgat taaaacggat
     4141 agaatattct ttactagttt gacctgtatg aaccacaaaa ttcaagcttt ctataacatg
     4201 tgaacttggg tgttcaaagc taaataaagc tccaaaataa tcttctttgt aggttagcaa
     4261 atcaattcgt tgatcctgac tttttacaaa ggagcaagtg tcatattctc cattcttacg
     4321 atggtaatga atgcgcatag ggtagttata cattttttat ttttcctttt tactttgttt
     4381 ctatttcact aataaatttt tgtcaatctc gtctcaatta acagacatag tcatattctc
     4441 taaactctgt ttttaaacga tccattacaa actttctagc catgcctcat ctctgacctg
     4501 gataccaagt tcttgtgctt tttgcagttt acttccagcg tctgcaccta ccacgacgag
     4561 gtcggtcttt ttagaaatac tacctgtcac tttggcaccc agactttcga gtttactttt
     4621 agcttctgag cgcttgagtc gttccaattt tcctgtcaat accacggtca aacctgacaa
     4681 ggctgcatcc gctactaccg tctgtccttt atagtccaga ttgaccccag tttctttcaa
     4741 ttctctgagc agaatttcag agccttctgt cgcaaaataa gtctgaagac ttttggcaat
     4801 cacgccacct agactttcaa tactagccac ttcctctgaa tctgcctgag acagattttc
     4861 aattgaatgg aaatattgaa gtaaaagctg actaaccttg cttccgacat gacgaattcc
     4921 caaaccaaat aagagcttct cggcagaatt ttcctttgat gcttggatag cctgatacag
     4981 tttagcagcg gacttttcct taaccccctc taaaaggagg aaatcctctt cttgcaaacg
     5041 ataaatatcc gccacatcct tgactaaatt agcagcaaaa agcttctcaa caatagatgg
     5101 accaaggcct gtaatattca tagcatcacg agaagcaaag tgaatcaagc cttccatgat
     5161 ttgagcaggg caacgcggat tgatacaacg tagggccact tcatcttcaa agtgcaacaa
     5221 gtcagagtta caacttggac agtttgtagg gatatctagt ttttcttcag aaacccgttt
     5281 ggactctacc acacgtaaaa cggcagggat gatgtcacca gccttatata caatgaccgt
     5341 atcgtctttt cggatatctt tttcagcaat ataatctaca ttgtgcaggg tcgcacggct
     5401 aacagtcgta ccggcaagtt gtactggtgt tagattagca gttggagtta caacaccggt
     5461 acggccaact gtccagtcaa ctgataagag ttgagcttct ttttcttcag cagggaactt
     5521 gtaggctact gcccactttg gagccttaac ggtaaaacca agttcttctt gacttgctag
     5581 gtcgttgacc ttgattacca ctccatcaat atcgtaaggc agattttccc gttcctgtcc
     5641 tacttcttgg ataaaattcc agatttcatc tatgttttca gccaagattc gcttaggatt
     5701 gaccacaaaa cctagttgtt ctaggtactt caaacccttt tcttggctat cacgagttga
     5761 agggctggct tcttgataga gaaacgttgc aagattacgc ttggcaacta ctgctgtatc
     5821 caactgacgc agagttcctg ctgccgcatt acgaggatta gcaaattcag gctctccatt
     5881 ttcttggcgc gcttggttaa cttggtcaaa ggaagcgcgt ggcatgtaac attccccacg
     5941 aactgtgata tctagttctt ctggcaaagt caaagggatg tccttaacac gcttgaggtt
     6001 ttctgtgata ttttcaccaa ttgaaccatc tccacgtgtt accccagcaa ccaaaatccc
     6061 cttttcataa gtcagcgaga tagataagcc atcgattttc agctcacaaa tataggtcgg
     6121 atgagccact tccttacgaa cacgcgcatc aaaagcatct agctcctcac gtgaaaaagc
     6181 atcctgcaaa ctataaagag gatactgatg actgtatttt tcaaaaccat ctaaaacctt
     6241 gccaccaaca cgatgagtcg gactgtctgc tagcacttgc tctggataag cagtttctaa
     6301 ctcgaccaac tcacggtaaa ggcggtcata ctcactgtct gaaaccgagg gattatcgct
     6361 ggtatagtac tcagtcgcat agcgattgag caaagcgact aactcattca ttcttttatt
     6421 cataagacca ttttaccata aaacaagccc tcctcacaaa cgagaagggc ggaaaaaaca
     6481 cttagtttga aattattttt gaaactcaag caaccttata tcaatttttc aaaatgagtt
     6541 cgaacataaa taaacgatat acaagacaag atgataacac cacttccaat tatcaggaaa
     6601 gaagagagat gtacacttgg caagactgtc ataaatcctt ttgcaatagg cataaataga
     6661 atagctaagg taaaaattgt actcagtact cttccaagaa attcgctctc aaccttggtt
     6721 tgtacttgag taaaaaagtg aatattaaaa atcgtcataa acaattcaca aactaaattt
     6781 ccagaaaagg aaagaaaagt tggaagtggt aatcccatca taaaaactcc gacacctgtc
     6841 aaagccagta aaatcaaaag attataaata ttagctttaa ttttactagc tagaagagcc
     6901 ccaatgatgg aaccaatagc ccccatagtt aaaatacttg cataggctcc ttctgacccg
     6961 taaagctgat tcgaaaaggg aagtagaaat tcaaaagctg caaaaaagaa attaacgctg
     7021 gaagctacca gcaaaaggaa gaaaatttct tgctgatgcc agatatagtg taacccatcc
     7081 ttgatatcta caaaaatatc tctcccagta aaagcctttt tctcttgaac ttttgcttcc
     7141 tcttttggaa ggaaagccac tagaacaaaa gcaatgaaaa aagtcagcga gtctagcagt
     7201 agcgtcatat ggagacttgc aaactgtaaa acaaggaagg aaagaacagg agagctaaca
     7261 cctacaacct gcaaaaccag ctctaggcga gaattataga tcacaatctc atctttctcc
     7321 accacttcag ttatgatagc tttattggct gtgcgagaaa aggcaaaagc aatagcctgc
     7381 acaatgttag caacaatcaa agcgccaatc atccagctat cattccttat gaaagaaata
     7441 gccagacaaa gaatcccaca aacaagatct gccgtcatta aaatcttacg acgagaaaaa
     7501 cggtctgaaa taactccgcc aaagggattg acgagaatag atgtgacgag ctcagaaatc
     7561 tgatacattc ctaaaactgt ctgtcctata gtccccatag aagccaacca gacactattt
     7621 ccataatcat agagcatatt tcccatttta ttgatagccc cacggctaat caactgcact
     7681 gcatagcgat tcatattaaa gctcctctca aattttgaaa ctattgtatc aaaaccgaaa
     7741 ggagcttttt attttttccc ttatttggga aaattaactt ttgacaaatt tttcgtagtg
     7801 ttcctgataa taggctactt gctctggaag acctaacaca tcaaaaatat gcatggcctc
     7861 ttgcatctgc ttacagcctt ctttacactg tcctttttga tataaggcaa aaccttttaa
     7921 ataatggaaa acattacgct cataaagctt aatacctttg tcaataatct tctctgtata
     7981 agcctcaaaa tagttggcat tataaaaaga agaatgctct aaacaatgct ggtaacaatt
     8041 gagggccaaa atcaacacta atctcttatg gcgactaatc tcttggtaaa attcctccct
     8101 ctccataact tctctaccaa tccgagtgac atagtctaca tcgtagaaac tatagaggtt
     8161 accgaaaaga atcaactcat acatggtcca ttcttctgtt ttgaagagat aatctgctac
     8221 cttatccaaa tcatcctgct tcatatcata actcgcatct ctttgacaaa tcagaccttg
     8281 tagcaaaatc cagttcagct caaaataaag ggaagtcgtc gaactcttag acttttcaag
     8341 ttgttctctt tgaagctttt gaaaacctgc aatatcgttt gaatggtaaa gtgggataat
     8401 ctgtgccatc atagacacat gttcatgatt atgaaaattc cttgccttat ccatgaaatt
     8461 ttcgattgtt acatgaatgt tatccaaaat ctcaaagaaa cgggagactg ccaggtcaga
     8521 ctccccaagc tcaaagcgag ataactgaga ggtagagcag gattcgcctg ctgcttcctt
     8581 taaagaataa tttccacttg ttcgaaattc acgaaatact tttccaagat gttccatctt
     8641 tacacctgat ctgataattc ttcccactca agcatagctt cttcctgacg atggctgatt
     8701 ttgtccagct cagcctgtaa ttccatgagt ttgtcggcat cgtttgtttc caacatttgt
     8761 tcagaaatgg cttggctttg actttctagc tcttcaattt cagcttctag actttcgatt
     8821 tgtcgcatga gtttgcgaac ttctttttga ctttctttct gggcctgata gtcattgact
     8881 ggacttgctt cctttgcttg attgctagtt gaagcttcct cagtctgact catttctgct
     8941 gttgctttct tctcaacata gtagtcgtaa tctccaaggt agagagttga accattctca
     9001 gacaattcca aaacatgagt tgccacacga ttgataaagt aacgatcatg actgacaaaa
     9061 agcaaggtac catcaaagtc aatcaaggca ttttctagca cttccttact atcaatatcc
     9121 aagtggttgg tcggctcatc cagaatcaaa aagttattgt tttccataga caatttagct
     9181 aaaagcaaac gagctttttc gccaccagat agcatgccga ctgatttttt aacatcatct
     9241 cctgagaaaa ggaaggcccc aagacggttg cggattttaa cttctggtgt cagtttgaaa
     9301 tcattccaga gttcatccag caccgtatta cttggtgtca gcttgctttg ggtttggtca
     9361 tagtaaccaa cctcaacatt agcgccaaag cgcttttcac ctttgataaa aggaatctgg
     9421 tccacaatag acttgataaa ggttgacttg ccgataccat ttggaccaac gatagcgaca
     9481 gcattcatct tacgaagatc taggttgata ggttgtgaca aaacttcccc gtcataacca
     9541 atagcagtat tttcaacagt caaaacaaca ttgcccgacg ttttttcaga ctggaaggtc
     9601 atgttggctg ctttcttgcc agcttcaggc ttgtccaaac gctccatttt ttctagttgt
     9661 ttacggcgag attgagcacg tttggtcgtt gaagcacgaa ctagattgcg attgacaaag
     9721 tcttccagag cagcgatttc cttctgttgc ttttcatagt tttttgcctc agtagctagc
     9781 ttttgctcct tcaactcaac aaaacgagag taattcccca catagcgatc caaggaatgc
     9841 ttggtcaaat ctagcgtaat tgtcgcaacc ttgtccaaga aataacggtc gtggctgacg
     9901 ataatgaggg caccgctata gtttaccaag taattctcta gccaggagat ggtttcaata
     9961 tccaagtggt tagttggctc gtccaagacc aagagattgg gcttttcaag gagcatttta
    10021 gctagagcca aacgagtatt ttgaccacca gaaagctcag caattttcat ctgccacata
    10081 gactcgtcaa acttgaatcc attcaaaatc gctcgaatat cagcttcata ggtaaagcca
    10141 cctgcttggc gaaaattttc agataagcgg tcataatctg acatcagttt atccaaatcc
    10201 tcaccagact tttcacccat ctccagctcc atctgacgca gttgtttatc tgtccgacgt
    10261 aagtcatcaa agacatgaag catctcatca tagatggtat tttcagactc aaaacggcta
    10321 tcttgagcta ggtaagacag agaaatatct tttttcttat tgatttctcc actagttggc
    10381 tcctcttctc caactaaaat cttcaaaaga gtagacttac ctgcaccatt tttcccaaca
    10441 agggcaatcc gatctcgttc atcaacctgc aggttgatat tatcgaaaag aacctctcct
    10501 gcaaaagaac gttcaatttt attagcttgt aaaataatca tacaagtagt atagcatgtt
    10561 tccctaaggc attcaagata atcgtaagtc
//
LOCUS       DAVMAH010000062        10552 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVMAH010000062 DAVMAH010000000
VERSION     DAVMAH010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.062"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            171..1049
                     /gene="truB"
                     /locus_tag="VYO94_001776"
     CDS             171..1049
                     /gene="truB"
                     /locus_tag="VYO94_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV1760367.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            1290..1592
                     /locus_tag="VYO94_001777"
     CDS             1290..1592
                     /locus_tag="VYO94_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1760368.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            1700..2338
                     /gene="udk"
                     /locus_tag="VYO94_001778"
     CDS             1700..2338
                     /gene="udk"
                     /locus_tag="VYO94_001778"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV1760369.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            2466..3806
                     /locus_tag="VYO94_001779"
     CDS             2466..3806
                     /locus_tag="VYO94_001779"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV1760370.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            3784..3996
                     /locus_tag="VYO94_001780"
     CDS             3784..3996
                     /locus_tag="VYO94_001780"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV1760371.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIDLEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            3993..4868
                     /locus_tag="VYO94_001781"
     CDS             3993..4868
                     /locus_tag="VYO94_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV1760372.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            4861..5676
                     /locus_tag="VYO94_001782"
     CDS             4861..5676
                     /locus_tag="VYO94_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV1760373.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     NLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            5669..6100
                     /locus_tag="VYO94_001783"
     CDS             5669..6100
                     /locus_tag="VYO94_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1760374.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            6107..7774
                     /gene="recN"
                     /locus_tag="VYO94_001784"
     CDS             6107..7774
                     /gene="recN"
                     /locus_tag="VYO94_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV1760375.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            7776..8504
                     /locus_tag="VYO94_001785"
     CDS             7776..8504
                     /locus_tag="VYO94_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV1760376.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGVVAED"
     gene            8583..10406
                     /gene="lepA"
                     /locus_tag="VYO94_001786"
     CDS             8583..10406
                     /gene="lepA"
                     /locus_tag="VYO94_001786"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV1760377.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         3111 a         1909 c         2586 g         2946 t
ORIGIN      
        1 acatattcaa aaacagaaca attgtcctcc tccagagatt gaggaattac aaagaattat
       61 agttaattaa attttgtaaa aaagagaata aaaggtagac gacgcctcag taaaaattgg
      121 cccggaaaaa agcgaagttc gaagcactga agggggagta gaaagcaaaa atgaacggta
      181 ttatcaactt aaaaaaagaa gcaggaatga cctcgcatga tgcggttttt aaactgcgta
      241 agattttggg aaccaagaaa attggtcatg gtggaacctt ggatccggat gtggtgggtg
      301 ttttgccgat tgcggttggc aaggcgacac gcatggtcga gtttatgcag gacgagggta
      361 agatctatga gggggaaatt actctgggtt attccacgac gactgaggat gctagtgggg
      421 aagtgatcgc agaaacccct gttttgtctc ccttggatga aaagcttgtt gatgaagcga
      481 ttgctagctt gactgggcct attacccaga ttccccctat gtattcggca gttaaggtta
      541 atggtcgcaa gctctatgag tatgcgcgtg ctggtcagga agtggagcgt ccagaacgtc
      601 aggtgaccat ttatcaattt gagcgaacaa gtccgatttc ttatgatggc caacttgctc
      661 gattcacttt tcgtgtaaaa tgcagtaaag ggacttacat ccgtactttg tcagttgatt
      721 tgggtgaaaa gcttggttat gcggctcata tgtcccattt gactcgtact agtgctgctg
      781 gcttacaatt agaagacgct cttgccttgg aggaaattgc tgaaaaagta gaggctgggc
      841 aattagattt tctccatcct ttagagattg ggacaggtga ccttgtcaaa gttttcctaa
      901 ctccagaaga ggctacagaa gttcgctttg gtcgttttat tgagctagac caaacggaca
      961 aagaactggc tgcctttgaa gatgataaat tgttagccat tctagaaaaa cggggcaatc
     1021 tctataagcc aaggaaggtt tttagctaga tcgtttagga ataaaaatcg ggtgatagat
     1081 aacaattgct tgataaaacc ccatactaat agtagaatgg ttttgggaat tataatattc
     1141 caattgttgc gagttgtagg tactcaaata atctatatag aaatttagag gtgtgaaatg
     1201 aagcaattta aaattctttc agataaatat ttagagtcca ttacaggttc tggtgggaac
     1261 ttaggcccag gatttggtgt gataattcca tgatgcgaaa tgagtttcga gaaagggtgg
     1321 agcaacttct tcaacaaaaa gaaataaatg aaaatagtga gttgagtcac ctgtttcgtc
     1381 ttgctataca aaatttagac agaaatgaaa aataccaatc ggtcatggcc aatttgagtc
     1441 aagggttgtc actttacctc atgacgcatc attaccaggc acctaagtct gtcattgatt
     1501 ttggtttatg gattgccaaa gctcctagcc aggaaagagg gagactggct ttcttgcaga
     1561 tgcttgctca aaccctacag ggctttcgtt aaaactgtcg aacatcagag ggaagactct
     1621 ggtgtttttt gctgatgaga ctataaattt tgtaaaaaat gtgatagaat agacgacgga
     1681 taaaataacg gaggatagca tgcaaaatag accaatcatt attggagtga caggtggttc
     1741 tggtggtggt aaaaccagtg tttcaagagc cattttatcg cattttcctg atgaaaagat
     1801 ttccatgatt gagcatgatt catactacaa ggatcagtct catttgacct ttgaagagcg
     1861 tgtcaaaacc aactatgacc atccttttgc ctttgataca gacttgatga tcgagcagat
     1921 taaggaattg ttggcagggc gtccggtgga catcccgacc tacgactata cagagcatac
     1981 acggagtagc aagacctatc gtcaggagcc tcaagatgtc tttatcgttg agggcatttt
     2041 ggtcttggag gacaagcgtc tgcgcgattt gatggatatc aagatttttg tggatacgga
     2101 tgacgatgta cgtattattc gtcgtatcaa gcgtgatatg gaggagcgtg gccgtagcct
     2161 tgatagcgtt attaaccagt acttaggtgt ggtcaaacca atgtaccacc agtttatcga
     2221 gtcaactaag cgttatgctg atatcgtcat tcctgaaggg gttagcaata ccgtggctat
     2281 cgacctgttg acgaccaaga ttgcaaagat tttggaagaa gctcgaaaca gcaaataatc
     2341 acatgtggag gccttgcctc ctttttctat ttttccctca taatggtaca taaatggaga
     2401 tttttaggca tatttttggt ataataatac ccatgaaaga gcaagtaaat gaatagtagg
     2461 tggagatgga aaagtattta tcggtaacaa ctttgaccaa gtatctgaaa atgaaattcg
     2521 ataaagaccc atacttggaa cgggtctatt taactggtca agtttccaac tttcgtaaac
     2581 gacctactca ccaatatttc tccctaaagg atgaccatgc agttattcaa gcgaccatct
     2641 ggtctgggat ttatcagaaa ttagggtttg acctggaaga aggaatgaag atcaatgtga
     2701 ttgggcgtgt acaggtctat gaaccaagtg gtagctactc catcatcatt gaaaaagctg
     2761 agcctgatgg ggttggggcg cttgcgattc agtttgaaca acttaagaaa aaattgacag
     2821 aagaaggcct gtttcaagaa cgcttcaagc aagctctgcc ccaattttct aagagaattg
     2881 gtgtagtaac cagccgtagt ggagccgtta ttcgagatat tatcacgacc gtcagcaggc
     2941 gattcccagg tgttgacatc cttctttatc cgaccaaggt tcaaggtgaa ggggctgcgg
     3001 aggaaattgc tagaaatatt gcgcgtgcta atcaacggga cgatttggat ttgctcatta
     3061 ttggtcgtgg aggtggttct attgaggatc tctgggcctt taacgaagaa attgtggtac
     3121 gagctatttt tgaatctcgt ttgccagtta tctctagtgt ggggcatgag acggatgtga
     3181 ccttggcaga ttttgtggca gatcgacgcg ctgcaacgcc aacagcggcg gctgaactgg
     3241 caacacctgt gaccaagttg gatgtattag ctcatttgca aaatcaggaa aaacggatgg
     3301 taacggcagt ccgaaatgtt ctatctaaga aacaagaggc tttgaaaaaa tgcagtcagt
     3361 ctgttatctt tagacaacct gagcgcttgt atgacggtta tttgcaacgc ttggaccaac
     3421 tgcaactgcg tttgaaacaa agtttgcgaa ctcggatttc tgataacaaa caattagttc
     3481 aagcaagaac tcatcaatta gtacaattat cacctgttac caaaatccaa cgctatcaag
     3541 accgtttagg acagttggac aagctcttag gtagccaaat ggcgttagtt tatgacgcca
     3601 aggttgctga ggccaagcga ctttcggaag ctttgctcat gttggatact agccgaatcg
     3661 tggcgcgtgg ttatgctatt gtcaaaaaag aagagtccgt tgtagattcg gttgagagtt
     3721 tgaagaaaaa agaccaagta acgcttttga tgcgagatgg tcaagtagaa ttagaggtta
     3781 aagatgtcaa aacaaaagaa atttgaggaa aatctagcag aactggaaac cattgtccaa
     3841 agtttggaaa atggtgaaat tgatctggaa gatgcgatta ctgcctttca aaagggcatg
     3901 gtcttgtcaa aagagctcca agctacgctg gacaaggctg aaaagacctt ggtcaaggtc
     3961 atgcaagaag acggaacaga aagtgatttt gaatgaaaaa gcaagaaaaa ttagctcttg
     4021 tcgagtcggc tttggaagat ttttatggag accagcagtt tgcctctagt ttacgggagt
     4081 ctgttctcta ttctattcat gctggtggca agcgtattcg gccttttctc ttgttagaag
     4141 ttctggaagc cttgcaggtt accatcaaac ctgctcatgc gcaggtagct actgccttgg
     4201 agatgattca tacagggagc ttgattcacg atgaccttcc tgctatggat gatgacgatt
     4261 atcgaagagg gcggttaacc aatcacaaga aattcggtga agctatggcc attttggctg
     4321 gagatgcctt attcttagac tcatatgcct tgattgcgca ggcagatttg ccaagtcaga
     4381 ttaaggtgga cttgattgcc aacttatccc ttgcttcagg tagtctgggt atggtggcag
     4441 ggcaagtttt ggatatggag ggcgaacacc agcacttgtc tctggaagaa cttcagacta
     4501 ttcatgccaa taagactggg aagttactag cctatccctt ccaagcggca gctattatag
     4561 ctgaattgtc acctgaaatg caggtgaagc tgaaaactgt gggtgaattg attggacttg
     4621 cttttcaagt cagagatgat gtactggatg tgacagctag ttttgaggaa atcggcaaga
     4681 cacctcaaaa ggatctgcag gcagaaaaat caacctatcc tgccctgttg ggcttggaag
     4741 agtccattgc cttttgtaac caaaccctgg atcaagctaa tgaaaaatta gaagaaattg
     4801 cccagcagct tccctttgaa acagaatcga ttgtaagtgt agtagaaagt ttgagaatca
     4861 atggctaagg aaagagtgga tgtactagct tataaacagg ggttgtttga aacgagagag
     4921 caggccaagc gaggtgtgat ggctggccta gtcgtagcag tccttaatgg agaacggttt
     4981 gacaagccag gagagaaaat tccagatgac accgaattaa aactcaaggg ggagaaactc
     5041 aagtatgtca gccgtggtgg tttgaaactg gaaaaggcct tgcaggtctt tgatttgtcg
     5101 gtggatggcg cgactacgat tgatatcggg gcctctactg gaggttttac cgatgtcatg
     5161 ctacagaata gtgccaagtt ggtctttgca gtcgatgttg gtaccaatca gttggcttgg
     5221 aaattacgcc aagacccacg agttgtcagc atggagcagt tcaatttccg ctatgctgaa
     5281 aagactgatt tcgagcagga gccgagcttt gccagtattg atgtgagttt catttccctt
     5341 aatctgattt tgccagcctt gcaccgtgtc ttggctgatc aaggtcaggt ggtagcactt
     5401 gtcaaacctc agtttgaggc aggacgtgag cagattggga aaaatggaat tattcgagat
     5461 gctaaggttc atcagaatgt ccttgaatct gtaacagcta tggcagtaga ggtaggtttt
     5521 tcagtccttg gcttggactt ttctcccatc caaggtggac atggaaatat tgaattttta
     5581 gcgtatttga aaaaagaaaa gtcagcaagc aatcagattc ttgctgagat taaagaagca
     5641 gtagagaggg cgcatagtca atttaaaaat gaataaaaaa gaaagacttg aaaaaattag
     5701 aagattggtg acagattatc aaatcggcac gcaagaagaa attgtagaac atttgaaaga
     5761 agcaggtatc actgccactc aggcgacggt atcccgagat atcaaagagt taggtattgt
     5821 caaaattcct ttgagagaca acacctatgt ctacgaatta ccaaaatcaa tcgtaaaaag
     5881 tctgcaactg gctgaagaca atatcgaatc ggctgaattg atggataaga tgatcaatct
     5941 ccaagttatt ccaggaaata cggcttttgt aaaagctcag ttaatcgaga cttttgcaga
     6001 caagattttt agctgtttga ctgatgatag ctcgatttta gtcattgcca gaagtggaag
     6061 tctagcagag gaaatctttg aacaagtaaa aaattggtag gtctatatgt tacttgaaat
     6121 ttcgataaaa aactttgcca ttattgaggc tatttccctc aattttgaaa aggggatgac
     6181 tgtcctgact ggtgaaacgg gtgcagggaa gtcgattatc attgatgcca tgaatatgat
     6241 gttgggagct cgtgcgacga cagatgttat tcgtcatggt gcaccaaagg cagagattga
     6301 ggggcttttc tcagttgaga atagtcgtct tttacaggaa atttttgatg agcaaggttt
     6361 agaattaggt gatgaaatta tcatccgtcg ggaaatcttg caaaatggtc gtagtatcag
     6421 ccgtgtaaat ggtcagatgg ttaatctgtc tgttttgcga gctattgggc aacatcttgt
     6481 agatattcat ggtcagcatg accatgagga gttaatgcgt ccccaactgc atatccagat
     6541 gttggatgaa tttggtgatg ccgctttttg ggacttgaaa gaaacctatc aaacgagttt
     6601 tgatgcctat cggaaaatgc gcaagcaggt tctggaagtc aagaaaaacc aacaggaaca
     6661 caaggcacgt atcgaaatgt tggaatttca aatggcagag attgaggcag caaacttgca
     6721 ggctggagaa gacttggatc tcaatcaaga gcgagataaa ctcctcaacc acaaaaatat
     6781 tgcggataca ctgaccaatg cctacagtat gttggacaat gaagattttt caagtctggc
     6841 caatgttcgt tcagccatga atgacatgga aagtgtcgaa gagtatgacc ctgaataccg
     6901 tgaaatttca agctctctgt ctgagaccta ctatgtttta gaagacatta gcaaacgttt
     6961 ggaagctatc attgaggacc ttgattttga tggcaatcgc ctgatgcagg ttgagaatcg
     7021 tttggacctc cttcatacta ttactcgtaa gtatggtggg actgttgatg atgttttgct
     7081 ttattttgcc aagattacgg aagaatacaa tctcttgaca ggcaataatc tttcgtctga
     7141 ggacatggaa gcagagctta agaagttgga agtcaatctt gtcaatttgg caggtcaact
     7201 tgcttctgct cgtcataatt tggctcagca actcgaagct gagattaaac aagaactgca
     7261 agatctttat atggaaaaag cccagtttca ggttcgtttt agtaagggaa aattcagtcg
     7321 tgagggaaat aaaatggttg agttttatat ttcaaccaac cctggagaag actttaaacc
     7381 cttggttaag gttgcttctg gaggggaatt atctcgtctc atgttagcca ttaagtctgc
     7441 cttttcacgt aaagaaggca agactagcat tgtctttgat gaggtggata cgggagtttc
     7501 aggtcgtgtt gctcaagcta ttgctcagaa aattcataaa attggtcagc atggtcaggt
     7561 tttggctatc tcccatttgc cacaagtaat tgcgattgca gattatcaat tctttattga
     7621 gaagattagt aatgaccatt caacggtttc gactgttcgt ctcttgacgg tcgaagagcg
     7681 agtggaggaa gttgccaaga tgttggcagg tgatgatgtg acagaagcag ccctgacgca
     7741 agccagagaa ttgttgagaa acagggagaa ataagatgac agattattat gtaattggag
     7801 atgttcacgg aaaagctggg atgctggaag accttctcaa aacctgggat ggtcagcccc
     7861 agttgctctt tctaggtgat ttgattgaca gaggtgagga tagtcaccgt gttcttgaaa
     7921 tggtcaagga cttggtggac aatcaagggg ctatctgttt gtccggaaac cacgagtata
     7981 tgtttttgac ttggctagat gacccagaag aaagttatga ccattatcgt cgcaatggtg
     8041 gagatacaac cattaactct atcctaggtc gtcccttgga tgcaccagtt gatggagtag
     8101 aagatgccaa gcgggttgcc gctgaagcgt cagacttggt cgaattcatt cgtcaaatgc
     8161 catttgtagt agagacagac aagtatatat ttgttcacgc aggtattgat ttgactttgg
     8221 acgactggca tgaaacaaca gattataaaa aagtatggct tagaaaacca ttccacggag
     8281 ctgaaaatca tactggaaaa accattgtct tcggtcatac accggtctat ggtttgttac
     8341 agcaagaacg cggtacatct gagctttgga ctacagaaga tggcaagatt ggaatggatg
     8401 gaggagctgt ttatggtggt gtccttcacg ggattgtctt tacagaccaa ggaatgacag
     8461 aacaccactt tatcgaaaat gacggcgttg tcgctgaaga ttagtactcc tagcagggta
     8521 tggtcttgtc aaaatatcaa aaacaattta taataaatag ataccctgaa aggaagagaa
     8581 tcatgaactt agaagaattg aaaaaacgac aggggaagat ccgtaacttc tctattatcg
     8641 cccatattga ccacgggaaa tcaactctag cagaccgcat tttggaaaaa acagagacgg
     8701 tttcaagtcg tgaaatgcag gcccagcttt tggatagcat ggatctagag cgggaacgtg
     8761 gaattactat taagttgaat gccatcgagt tgaattacac tgcaaaagat ggggaaactt
     8821 atattttcca cttgattgac acaccagggc acgttgactt tacctatgaa gtttcacgtt
     8881 cgctagctgc ctgtgagggt gctattttgg tggtcgatgc ggctcaagga attgaggctc
     8941 aaactcttgc caacgtttat ctggctttgg ataatgattt ggaaatcatg cctatcatta
     9001 ataaaattga cctgccggct gcagatccgg agcgcgtgcg tacagagatt gaagatgtga
     9061 ttggtttgga tgccagtgaa gcagttttgg cttctgccaa ggctggtatt gggattgaag
     9121 aaatcctcga gcaaattgta gaaaaagtac cagcaccaac gggtgatgtg acggcgccac
     9181 ttaaggcctt gattttcgac tctgtttacg atgcttaccg tggggttatc ctccaagtgc
     9241 gtgtcatgga cggagtggtc aaacctggtg ataagattca gctcatgagc aatagtaaga
     9301 cctttgatgt ggccgaagtc ggtattttta caccaaaagc ggttggtcgt gatttccttg
     9361 cgactggtga tgttggttac attgcggcgt ctatcaagac ggttcaggat actcgtgtgg
     9421 gtgataccgt taccttggca accaatcctg cggcagaacc attacatggt tataagcaga
     9481 tgaatcctat ggtctttgcg ggtctctacc caatcgaatc aaacaagtac aatgacctgc
     9541 gtgaagcgct tgaaaaattg caactgaatg atgctagtct tcagtttgaa ccagaaacat
     9601 ctcaggcact tggatttggt ttccgttgtg gatttcttgg acttctccat atggatgtta
     9661 ttcaggaacg tttagagcgt gagttcaata ttgacctcat catgacagct ccgtctgtta
     9721 tttacaaagt taatttgacc gacggtgagt ctatggatgt gtctaaccca tctgagtttc
     9781 cagacccaac taagattgcg accattgaag agccttatgt caaggcgcaa atcatggtac
     9841 cacaggagtt cgtcggagca gtaatggagc tagctcagcg taagcgtggg gactttgtga
     9901 ctatggacta tattgatgat aaccgtgtca atgttatcta tcaaattcct cttgctgaaa
     9961 ttgtctttga cttctttgat aaacttaagt cttcgacacg tggttatgca agctttgact
    10021 acgaattgtc agaatatcgc ccatctaagc tggtgaaaat ggatatcctt ctcaatggag
    10081 ataaggtgga tgccctcagc tttatcgttc acaaggactt tgcctacgaa cgtgggaaac
    10141 tcatcgttga taaactcaag aaaatcatcc ctcgccaaca atttgaagtt ccaatccaag
    10201 cggctattgg acacaagatt gtcgctcgta ctgatatcaa ggcccttcgt aagaacgtac
    10261 ttgctaaatg ttatggtggt gacgtttctc gtaagcgtaa actccttgaa aaacaaaaag
    10321 ctggtaagaa acgcatgaaa tccatcggat cagttgaagt tccgcaagaa gccttcctca
    10381 gcgtcttgag tatggatgaa gaataagtta tcagaaatgc ctttccttgt tcacaggaaa
    10441 tttatataag aatcaatagt aaagcaggct tagatagtct gcttttttag tttttatact
    10501 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttact gtatgtatgg tt
//
LOCUS       DAVMAH010000063        10523 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVMAH010000063 DAVMAH010000000
VERSION     DAVMAH010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10523
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.063"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            1..615
                     /locus_tag="VYO94_001787"
                     /pseudo
     CDS             1..615
                     /locus_tag="VYO94_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            515..961
                     /locus_tag="VYO94_001788"
     CDS             515..961
                     /locus_tag="VYO94_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1760378.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1100..2404)
                     /gene="eno"
                     /locus_tag="VYO94_001789"
     CDS             complement(1100..2404)
                     /gene="eno"
                     /locus_tag="VYO94_001789"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV1760379.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2568..3014
                     /locus_tag="VYO94_001790"
     CDS             2568..3014
                     /locus_tag="VYO94_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV1760380.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(3011..4126)
                     /locus_tag="VYO94_001791"
     CDS             complement(3011..4126)
                     /locus_tag="VYO94_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV1760381.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4240..4464)
                     /locus_tag="VYO94_001792"
     CDS             complement(4240..4464)
                     /locus_tag="VYO94_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1760382.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAE"
     gene            complement(4409..4780)
                     /locus_tag="VYO94_001793"
     CDS             complement(4409..4780)
                     /locus_tag="VYO94_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV1760383.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRTRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4839..6272)
                     /gene="glgA"
                     /locus_tag="VYO94_001794"
     CDS             complement(4839..6272)
                     /gene="glgA"
                     /locus_tag="VYO94_001794"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV1760384.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6269..7408)
                     /gene="glgD"
                     /locus_tag="VYO94_001795"
     CDS             complement(6269..7408)
                     /gene="glgD"
                     /locus_tag="VYO94_001795"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV1760385.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7398..8540)
                     /locus_tag="VYO94_001796"
     CDS             complement(7398..8540)
                     /locus_tag="VYO94_001796"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV1760386.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8530..10458)
                     /gene="glgB"
                     /locus_tag="VYO94_001797"
     CDS             complement(8530..10458)
                     /gene="glgB"
                     /locus_tag="VYO94_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV1760387.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSAIKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3193 a         2322 c         1876 g         3132 t
ORIGIN      
        1 actgaaatag cttctgaatt tggctgtcat ccaactacca tccactatgc gctcaaagct
       61 atgggctaca ctcgaaaaaa agaaccacac ctactatgaa caagacccag aaaagtagcc
      121 ttatttctta agaattttaa tagattaaag cacctagcac ctgtttagat tgatgaaaca
      181 ggattcgata cttattttta tcgagaatat ggtcgctcat taaaaggtca gttaagaaga
      241 ggcaaagtat ctggaagaag atatcagagg atttctttgg ttgcaggtct aacaaatggt
      301 gagttaatcg ctccaatgac ttacgaagag atgatgacga gcgacttttt tgaagcatgg
      361 tttcagaagt ttctcttacc aacattaacc acaccatcgg ttattattat ggataatgca
      421 agattccata gaatgggtaa gttagaactt ttatgcgagg agtttgggca taaactttta
      481 cctcttcctc cctactcgcc tgagtacaat cctattgaga aaacatgggc tcatatcaaa
      541 aagcacctca aaaaggtatt accaagttgc aatacctttt acgaggcttt tttgtcttgt
      601 tcttgtttca attgactata taaattgtct aagcgaaaca accgataaga attggcacaa
      661 aagcgaccgt atttttgtta ccaatacagg aaaaccagtt catagttcta tcttgagcaa
      721 gtctctccag cgagcaaacg aacgccttaa aaaaccaatt cccaaacatc tgtcccctca
      781 catcttcaga cacaccacta ttagcatctt atcagaaaat aaaattcctt taaaaacaat
      841 cacggacagg gttggtcatt ccgactctga agtcactact tccatctaca cccacgtcac
      901 aaagaacatg aaagatgaag caatcaatgt actggataaa gttatgaaaa agatttttta
      961 aaaaagtttt gccccttttt tgtcctctaa atacaaaaat agcccttcgg ataaaatccg
     1021 aggggctaga aacgttgtta aatcaacggc cgaacttttg aatttcatgg ttcgggataa
     1081 aatagttcac tgaactattt tattttttaa ggttgtagaa tgatttcaat ccacgatatt
     1141 cagctacttc accaagttgg tcttcgatac gaagcaattg gttgtattta gcgatgcggt
     1201 ctgtacgtga aagtgaacca gtcttgattt gtcctgcgtt agttgcaact gcgatatcag
     1261 cgattgttga atcttcagtt tcacctgaac ggtgtgatac aacagcagtg taaccagctt
     1321 ctttagccat ttcgatagct tcaaaagttt cagtaagagt accgatttgg ttaactttga
     1381 taaggattga gttagcagca ccttcttgga taccacgtgc aaggtagtca gtgtttgtta
     1441 cgaagaagtc gtcaccaaca agttgtactt tcttaccaag acgttcagta agagctttcc
     1501 aaccatccca gtcgttttca tccataccat cttcaatagt gatgattggg tatttgttaa
     1561 ccaattcttc aaggtagtcg atttgttctg cagatgtacg aacagcagca ccttcacctt
     1621 caaatttagt gtagtcgtaa actttacgtt ctttatcgta gaattctgat gaagcacagt
     1681 caaatccgat aaatacgtct ttacctggta catatccagc agcttcaatc gcagcaagga
     1741 tagtttcaac accatcttca gttccttcga aacgaggagc gaatccacct tcgtcaccta
     1801 cggcagtttc caaaccacgt gatttaagga ttttcttaag agcgtggaag atttcagcac
     1861 cgtaacgaag ggcttcttta aatgttggcg caccaactgg caagatcatg aactcttgga
     1921 aagcgattgg agcgtcagag tgagaaccac cgttgatgat gttcatcatt ggagttggaa
     1981 gaactttagt gttgaatcca ccaagatagc tgtaaagtgg gatttcaagg tagtcagcag
     2041 cagcacgagc tacagcgata gacacaccga ggattgcatt cgcacccaat ttacctttgt
     2101 taggagtacc gtcaagtgcg atcatagcac ggtcaatagc ttgttgatca cgtacatcgt
     2161 agccaatgat agcttcagca atgatgttgt ttacgttgtc aacagctttt tgtgtaccaa
     2221 gaccaccgta acgagatttg tcaccgtcgc gaagttcaac tgcttcgtgt tcaccagtag
     2281 aagctcctga tggaaccata ccacgtccga aagcacctga ttcagtgtaa acttctactt
     2341 caagtgttgg gttaccgcgt gagtctagga cttcgcgagc gtaaacatca gtaataattg
     2401 acatttttta ctctccttat gagttaaatt ttttacacct ctataatacc ttaaaacccc
     2461 tcctttttca agaaaaaacg ttatctttgt gcaacttttc cttaacttta taaagtaatc
     2521 gctttctttt gtctgtttta ttctaacttt tatgatatac tgttttcatg acagatttat
     2581 caaaacaatt acttgaaaaa gctcatggtg ggttaaaaat aaatccggat gagcaaagac
     2641 gctatcttgg tacttttgag gaaagagttc ttggatatgt agatattgac acagcaaata
     2701 gccctcagtt agaaaaaggc tttttattta ttttagaaaa ccttcaggaa aaagcagagc
     2761 cactatttgt gaagatttca ccaactatcg aatttgataa gcaagttttc tacttaaaag
     2821 aagcaaaaga aactgatagt caagccacca tagtatctga agagcatatt acttctcctt
     2881 ttggcctggt tattcatagc aatgcaccag ttcaagtaga agaaaaagac cttcgacttg
     2941 cttttccaaa actttgggaa gttaaaaagg aagaaccagc caaaacatcc ttatggaaga
     3001 aatggtttag ctaaatcttg cacatattta ataagtgccc aatattggca gccgtgcgct
     3061 ccagatagag actggcattt ttcaaactat cttctaaagg ttcacttttc tccaaaatag
     3121 aaaagacagc ttggatattt tcaaatggta ggggaggtaa atcttcagca agactaccgc
     3181 aaatagcaat aacaggaact ccaacagggg ttctttttgc aacacctata ggcgctttcc
     3241 cagcaaagct ttgactatca agtcttcctt ctccaacaac aaccaagtca gcatctgaaa
     3301 ctttcttatc aaagttgatt aagtccaagc aggtatcaat tccagacacg atacttgcct
     3361 gagcaaaggc acacaaacca ccagcaaggc ctccacctgc tcctgctcct ttaatttcta
     3421 atgttgcagg tgagaatttt tcataaaaat cttggatcgc ctgatctacg actgcaaaca
     3481 tagtcggatg tagacctttt tgattgccaa aagtgtaagt cgcaccttga tgaccacata
     3541 agggactcac gacatctgct aaaatatgaa tttgaacacc ttcaggaatt ttatagcaat
     3601 tttctgttga aacagaagct aagtttaata aggattgacc ggaagcaggc aagacatttc
     3661 catccctatc ataaaattga taacctaaac cagcagcaat ccccagtcct ccatcattac
     3721 tggccgtgcc accaacaccg atataaatat ctttaatccc tttagaaatg agatggagaa
     3781 tcaactctcc aataccacaa gtttggattt gaagtggatt tcgtttctct agcggaattt
     3841 ttccaagacc aaccaagtca gctacttcaa atagtgccag ttcccctttt tgaaaatagc
     3901 gcatggcttc tttttgtcca aaagggtctg tcacttggat ccatttttct tttaggtcaa
     3961 gagaatgtcg gatagcatct acagtacctt ctcccccatc accaacaggg cagaggagac
     4021 attctacatc tgctatcgat tgttggaagc ctctttttat tgcttcagct acctgttgag
     4081 ctgtcaagct ttccttaaac gaatccggtg caattacaat cttcatattt tccctcattc
     4141 taaacagtca atcaaaggaa gaacttctaa aaaatccctc ttgtcaacat gatgtggtat
     4201 ttcttttttg agcatttctt tggaacaaaa ggcgattcct cactccgccg acttcaacat
     4261 taatagatta ttgaccccat caccgattgc caccgttctt tctttagaaa gttttagttt
     4321 ctttctccat ttttccagag tttctttttt gacctgggga cttataattt gtccaactaa
     4381 ttttcctgtt aaaagacctt ctttgacttc aagctggttg gcagtgaaat aggcaatacc
     4441 aagggatttt gctaatctct ccaactattg gtgtaaatcc accagacacc agaccaacta
     4501 ggatgccatt cttttggaga atagagatga actctgggac atttagcgat agatgaattg
     4561 agttgaagac gttatcaaag accaaaatag gaagaccttc caacaaggac actcttgttc
     4621 ttaaactgct ttcaaagacc aactctcctc gcattgctcg acttgtaatc tgcgaaattt
     4681 ctgcctcatg acctgcctct ctccctaaaa gatcaatcac ttcttctagg attaaggttc
     4741 catctacatc caaaacacac aagcctttta cttgagacat cagttctcct ctctaaacag
     4801 cctaaaaatc gtatgaagtc atcatacgat tttatctatt aattaactaa actatggtac
     4861 aagtcaaggt atgacttgca ggctgtatcc catgagaagt cactctccat agcttgtttt
     4921 tgtaggtttc tccaaatgtc tggatggttt ctatacaagt ccaatgctgt ttggaaagtc
     4981 caatttaacc aataaggaga tagattgtca aagctaaagc cagtaccgct tccttcgatt
     5041 ggattgaaag cgcgaactgt atctcgcaag cctccaactt catggaccaa tggcaaggtt
     5101 ccataacgca tagccatcat ttgagacaag ccacacggtt caaaacgact tggcatgagg
     5161 aagaggtcac aagcagcgta gatttcctga gcaagtttga catcaaaagt gatatttgtt
     5221 gatagcttgt ctgggtaaat ctgagcaaac catgagaaag ctccttcaaa ggctggatcg
     5281 ccagttccca aaagaacaat ctgaacatct tcttgcaaga tatggtgaag actttcgacc
     5341 accacatcaa aacctttttg acgtgtcaaa cgagaaacaa ttcccaccag tggaacgtct
     5401 gctctaacag gcaagccaac tctttcttgc aattttgcct tatttttggc tttcccagac
     5461 aaatcttcct gattgaaatg atagtctaaa agagcatccg tctgaggatt ataaagatca
     5521 gcatcaatcc cattcacgat accagatact ttaccagact ccattttaag aatctgatcc
     5581 aaattacatc caaactgact agtcataatt tcatgagcat agctaggtga aacggttgaa
     5641 acacggttcg catagagaat acctgccttc atccagttca gacagttgtt ccatcgaagg
     5701 gtgccatcag cgtaacgttc aaagccaact ccaaacaaat cacccaacat tccttctgaa
     5761 aattgtcctt ggaattctaa attatgaatg gttaaaactg tttcaatgtc ctcataggct
     5821 tgaatccaac ggtatttttc cttcaacaag aaaggaatca tagctgtatg gtagtcatga
     5881 acatggagaa gatcaggaat aaagtcaatc ctttccatag cctcaatggc agccagttgg
     5941 aaaaaggcaa agcgttctcc gtcatcaaaa tcaccgtaaa catgaccacg gaagaaataa
     6001 tattgattgt caataaagta gaaggttaca ccatttaata ctgttttctt aattccacaa
     6061 tactgtctgc gccaaccaac gctcacctca aaatgaagca catcttcaat ctgatttcca
     6121 aatttagcct ctaccatatc atagtagggt aaaatcactg caacttcgtg cccagctttt
     6181 accagtgatt ttggaagagc gccaatgacg tctcccaaac cacctgtttt tgaaaagggt
     6241 gcaccctctg ctgctacaaa taaaattttc atgaatgaat atcctctgtt actttagcac
     6301 ctttcttaac cacaactgga tgttctgcag ttcctcgaat cacaacacca ggctcaactt
     6361 caaccccttt gtccaagata gcatattcga cctgagcccc ttctccaata acaacacgag
     6421 ggaagagcag gctatcttta accaagctat ccttatggac atgaatatta cgtgatagaa
     6481 cagaattagc tacttgacct tcaataatac taccagaggc aaactgagaa gtgcttacct
     6541 tagatgtatt agcatagtaa gttggctctt cgtttttgac ctttgtataa atcttttggt
     6601 ttggtgagaa aagagaatag aatttttgtg attcaagcat atcgatattc gcttgataat
     6661 aagatttaac agagtgaata ttggctagat agcctgtgta ctcgtaggcg aaagctccct
     6721 cttttacagc caaatcccgt aaaacatagc gcaatttctc tggatgttct tttttagctt
     6781 cttcttccaa gtgttcaatc aaccaaggtg tatcaacgac aaagatatct gtagacatat
     6841 tgaacgtttc agctgttgac ttgctatcaa agagtttatg agaaagaaca tggtctgttt
     6901 catctacatc caagattgca tttacttctg aaatatcttt cttagctagt tttttataaa
     6961 ctacagtgat aggctctttt gttgtactat gtaggtggaa aacttggttc aaatcaatgt
     7021 taataagaac atcgcagttg agggcaaccg tttggtttga gccagaacgt ttcaaataag
     7081 taagaagctg ttggtagtat tcttttccaa ctgtactact ttctacacgg gtattgtaaa
     7141 ttcctagata gtaatggcta agaagggttg ataagcccca ctcgcgtcct gaacgaatat
     7201 ggtcaaatac tgagctgata ttatcctgct ggaaaatacc aaagacacta cgaacacctg
     7261 cattagcaag gcttgaaagt gggaagtcaa tcaaacgata tttcccacca aatggcaaac
     7321 ttgctactgg acggtggtcc gtcaatgtcg acatattgtg aaaaccaact gtatttccta
     7381 aaatggcaga atatttatca atcttcatct gttgctaccc ccactacttc attatatcct
     7441 acaacttgta cttcatctgt tccatcaatt tcgacaccgt cagaaataat cgcaccttca
     7501 ccaataatgg cacgtttaat cttagctcct tgaccaatga tagctccact catgataact
     7561 gaatcaagga cttccgctcc ttcgcgaact tgcgcgcctg ttgaaaggat agaatgttta
     7621 acagttccat caacgaaaca tccgtctaca actaatgagt cttccacatg agcatttgcc
     7681 ccgaggaagt ttggtggtga aatcaagttt cttgagtaaa tcttccattg acggttacga
     7741 ctatccaagg cattttctgg agaaatatac tccatgttcg cttcccaaag tgactcaata
     7801 gtaccaacat ctttccaata accactaaat tcgtaagcat aaacactttc acctgactca
     7861 aggtaatttg gaatgacatt tttaccaaag tctgacatgc caaccttgct cttttcagca
     7921 gcgactaaca tattacgaag gcgttgccaa tcaaaaatgt agattcccat agaagctttt
     7981 gtagatttag gttgagctgg tttttcttca aattcaacaa tacgattgtt agcatctgtg
     8041 ttcatgatac caaaacggct tgcttcttta agagggacgt ctaaaactgc tactgtcaag
     8101 ctggcattat tatccttatg agactggagc atatcatcat agtccatttt gtagatgtgg
     8161 tccccagaca aaatcaagac atactcagga ttgacactgt cgatatagtc gatattttgg
     8221 taaatagcgt gactagtccc ctcaaaccaa cgatttcctt cacttgcaga ataaggttga
     8281 agaatagaga cacctgaatt aataccgtct agtccccagc ttgaaccatt cccaatatgg
     8341 ttgttgagag caagtggttg atactgtgta acaaccccaa cattatgaat ccctgagttg
     8401 gcacagtttg atagggcaaa gtcaatgata cggtagcgcc caccaaattg cacagctggt
     8461 tttgcgatgc tttgagtgag tttaccgaga cgagttcctt gcccaccagc aagaatcaaa
     8521 gctaacattt catttttcat tttctactcc tttttggttt ttatttgtga cggttttagt
     8581 agatttcaag cgacgtttga ttttccatac acttgctccc atagccggta gggtaaaggt
     8641 taaggtctgc tcataatctt tccatagtcc ttcttgcgtt tgaacagttt gattatgttc
     8701 tttccaaacg cctccccact cttccaactc agtattccat acttcttcgt aaattcctgc
     8761 aacgggtagt ccgattgtaa aatctttccg ctcaacaggt accatattaa agatacagac
     8821 taacatttct ccctttttac ccttacgaat aaaggaaaga acactctggt ctcgattatc
     8881 cgcatcaatg atttcaatac catcatagct ggtatcaatt tcccacagac agcgatgatc
     8941 tttgtaaaac tggtttagct gagaagcgaa atacttcatc ttagcattca ttgggtcttc
     9001 taggttagac cattccaact gttcttcaga tttccattct agaaattgac cgtattcgct
     9061 acccatgaag agcaatttct taccagggtg acaaatttgg tacgtataga gattgcgcaa
     9121 gcctgcgaat tgattgtaac gatctcccca catcttatgc atcatactct tcttgccatg
     9181 aaccacttca tcgtgcgaga atggcaagag ataattctcc ttgaaaacat acataaagct
     9241 gaaagtcacc aggttaaagt catatttacg atagatcgga tcttcttcgt agaaacggag
     9301 gatatcattc atccagccca tgttccattt gtagtcaaat cctagaccac caatctcttt
     9361 cattcccgta atcttgatcg cagacgaact ttcttctgca atcatcatca catctggata
     9421 ttctaactta ataacctcat tcaagcgctg aaggaaataa taaccttcat agttgagatt
     9481 tccgccatct ttattaggtg tccatggagc atcatcatag tccaaataga gcatgttgct
     9541 aacagcatcc acacgaatac catccaaatg atagacatca atccaatgct taatgcaaga
     9601 aattaagaag gactggactt cattttttcc aaggtcaaaa ttaagggcac cccaaccatg
     9661 gttatgagcc ttattatggt cttggtattc aaaagtcggt gtcccatcat aataggctaa
     9721 ggcatcatcg ttgatggtaa agtgacctgg tacccagtcc acaataaccc caatattatg
     9781 ggtatgacac tcctcgacaa aatcttgaaa ctcctctggt cggccataag catgctctaa
     9841 agcgaagtaa cccataagct gataccccca actcaagccc aaaggatggg acatcaaggg
     9901 cataaactca atatgagtat agttcatttc aacgagataa ggaatgagtt catccttgag
     9961 ctgggcaaaa ctataaggac tgccatcaga atttcttttc catgatccag cgtgaacttc
    10021 ataaatattg acaggacgct cttcaaagcc ccaacgtttt cttcgtgcca gccaaagtcc
    10081 atccttccat ttcttctcag gaagctctgt tacgattgcc cctgttcctg gacgagcctc
    10141 atacctgaca gcaaaagggt caatcttcat cagttgatga ccattttgac gtgtgacatg
    10201 atatttgtaa atatgccctt cttgagccat attggtaaag acttcccaga ccccaaaatc
    10261 atttcttacc attggaatct gattttcaat ccagttggta aaatcaccaa ccaagtgaac
    10321 agcctgagca ttaggtgccc aaacacggaa ggtatagcca tgctctccat ttagttcttc
    10381 cctatgtgct cctagataat gttggagata aaaattttca cccgtcataa aggtttttaa
    10441 tgcttctcta ttatccatat actccccttc tcctgtaagc gttttctatg tttttattat
    10501 actacctttt tagagaagat tca
//
LOCUS       DAVMAH010000064        10498 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVMAH010000064 DAVMAH010000000
VERSION     DAVMAH010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.064"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(<1..1124)
                     /locus_tag="VYO94_001798"
     CDS             complement(<1..1124)
                     /locus_tag="VYO94_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1760388.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNVKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFPRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYYSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWLDG"
     gene            complement(1175..1339)
                     /locus_tag="VYO94_001799"
     CDS             complement(1175..1339)
                     /locus_tag="VYO94_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV1760389.1"
                     /translation="MGKIVAIDLFNGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            complement(1420..4071)
                     /locus_tag="VYO94_001800"
     CDS             complement(1420..4071)
                     /locus_tag="VYO94_001800"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV1760390.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VNLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPVFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ECDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(4083..5046)
                     /locus_tag="VYO94_001801"
                     /pseudo
     CDS             complement(4083..5046)
                     /locus_tag="VYO94_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
     gene            complement(5048..5605)
                     /locus_tag="VYO94_001802"
     CDS             complement(5048..5605)
                     /locus_tag="VYO94_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760391.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            complement(5592..6041)
                     /locus_tag="VYO94_001803"
     CDS             complement(5592..6041)
                     /locus_tag="VYO94_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEV1760392.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(6454..6849)
                     /locus_tag="VYO94_001804"
     CDS             complement(6454..6849)
                     /locus_tag="VYO94_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1760393.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASHFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(6945..7199)
                     /locus_tag="VYO94_001805"
     CDS             complement(6945..7199)
                     /locus_tag="VYO94_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV1760394.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7209..8543)
                     /locus_tag="VYO94_001806"
     CDS             complement(7209..8543)
                     /locus_tag="VYO94_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV1760395.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8543..8776)
                     /locus_tag="VYO94_001807"
     CDS             complement(8543..8776)
                     /locus_tag="VYO94_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV1760396.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            8807..8881
                     /locus_tag="VYO94_001808"
                     /pseudo
     CDS             8807..8881
                     /locus_tag="VYO94_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(9089..9229)
                     /locus_tag="VYO94_001809"
     CDS             complement(9089..9229)
                     /locus_tag="VYO94_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760397.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(9226..9408)
                     /locus_tag="VYO94_001810"
     CDS             complement(9226..9408)
                     /locus_tag="VYO94_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760398.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            complement(9410..10189)
                     /locus_tag="VYO94_001811"
     CDS             complement(9410..10189)
                     /locus_tag="VYO94_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760399.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT         3079 a         2306 c         1866 g         3247 t
ORIGIN      
        1 tctccatcaa gccaaaaata atggttatcg gaatctaaat acgatgagtt taaaatatta
       61 ttacaaatta tttgatttgc tccaccagga atatatctca ctactaaatt ctgtttaaga
      121 ttctcactac ctgaatgagt gataacaaac tctagaatat atttagctag tctatcttca
      181 acataaatca tcttcctaga ataatacaca tcacctaatt caaaaaatgc atcctgataa
      241 tcaatgtttt caataacatc taccttttct ccgtttttca ctaaaagttt cacggcttct
      301 ctaggaaaat cttttataag ttgtgtagaa tgtgtagtga taataatttg atgtttttta
      361 tttaaacact cttgaagtaa aaactcttta aatttataga ttgcactcgg atgaagtgag
      421 atttcaggtt catctattaa tattaatgaa tttgattgcg catttactat atcatttact
      481 aacaaaataa ttctagcctc acctgttcct gcaaaagcct cggaatattc ttttccagat
      541 tttttcatcc aaatagtttt ggaagctttt atatcatcac cttttgaata caacttatgt
      601 gttaaaattt gaatgtctgt ataagattca tccattattt cactaataat ttcacaaact
      661 ttatcatcaa ctttaacatt atctataacc atttcctttt tataacgcgt atagctactt
      721 gtattattct ttaaaatatc agcaactggt ttagatcgta atcttataaa atcttgttta
      781 ctacgttgag tagaaatttt tttaaaatta tagtgataga aaaataaatc aaaagcagaa
      841 acatattctt tacaatcaca aaagacaaca tttttttcaa tgccatccca tctgtctgtc
      901 gaagaacttc caatatattt atttttgggt aatctttcca tctcatattg tttttgagga
      961 gcatatggtt cccaataatc taatcctttt tttgttccag aacggccttt aagaacttct
     1021 acatttctag aagctttaac gttataatat gaatagatta aacattgttt cccatccact
     1081 tcatctattt gatcaacatt tgtactaaac caatattcag acacactttt attggctgga
     1141 gaaccatata aagcttgtaa aattgaagtt ttatttactc catatctatt acagacacct
     1201 caggattatt taacttataa gttttaacag ctacggaatc aatttcaaca gcaacttgaa
     1261 catctatgcc tgatttttta aggccacttg tagtgccacc tgcaccgtta aataaatcaa
     1321 tagcaacaat tttccccata gtattctcct aaagtttctc ctttttatta taacattatc
     1381 aaatgtaaaa cccaacccga tagggttagg tttttaacat catttcacca acttcttcat
     1441 ctcatcaata cgtgcgacgg tcgcgtcata tttagcttgg tagtcagctt gtttgtcgca
     1501 ttctttttgg acgacttctg gtttggcgtt ggctacgaag cgttcgttag agagtttctt
     1561 accaaccatg tccagttctt tttgccattt agcaagttcc ttgtcgagac gggccagttc
     1621 ttcttcaaca ttgaggagat cggccagtgg caggtagatt tctgctcctg tgatgacact
     1681 tgacatagcc agttcaggtg cagggatggt tgatgcgatt tccaaatgtt ctggatttgt
     1741 aaagcgtttg atgtagttga cattgctgtt aaagaaggct tccaagtcac tatcgctagt
     1801 cttaacaagg attgtgatag gtttgcttgg tgctacattt acttccgcac gcgcattacg
     1861 aacggcacgg atcaagtctt tgagactttc cacaccagtg tgggcagcaa ggtcctcaaa
     1921 gactgggttg acagttgggt atgctgctgt cacgatagag ccttcagcgt actgaccaaa
     1981 gatttcttct gtcacgaacg gcattattga gtgaaggaga cgaaggattt tatccagcgt
     2041 atagaggaga acagatcgag taattacctt atcgtcttca ttgtcgctgt aaagaacttc
     2101 cttggtcaac tcaacatacc agttggcaaa ttcttcccaa atgaagttgt aaaggatatg
     2161 accagccaca ccaaactcga acttatcaaa gttttcagta acttttgcaa tggtttcgtt
     2221 gagattgtgg agaatccagc ggtccgtcac attaccagcc tcacctgttg caacttttgt
     2281 gacattgtca tgcgccacat ccagcgtcaa acctccattg ttcatgagga tatagcgaga
     2341 aatgttccaa atcttgttaa taaagttcca tgaagcatcc attttctcat aagagaaacg
     2401 cacgtcttgt cctggcgcag aaccgtttga aaggaaccat cgaagggcat cggcaccgta
     2461 tttctcgata acatccattg ggtcaatccc gttaccgaga gacttagaca tcttgcgtcc
     2521 ttgctcgtca cgaataagac cgtggataag gacgttttgg aatggttgac ggcctgtgaa
     2581 ttccaatgac tggaagatca tacgagacac ccagaagaag atgatgtcgt aacctgttac
     2641 caaggttgaa gttgggaaat aacgtttaaa gtcttctgag tcgacttcag gccagcccat
     2701 ggttgaaaat ggccagaggg cagaactgaa ccaagtatcc aagacgtctt cgtcctgagt
     2761 ccatccgtca ccttctggag cttcttcgcc gacatagatt tcgcctgctt cattatacca
     2821 agcagggatt tggtgacccc accaaagctg acgagagata acccagtcgt ggacattttc
     2881 catccattga aggaaggtat cgttgaaacg aggtgggtag aattcgacct tgtcctctgt
     2941 gtcttggttg gcaatggcgt tcttagccaa ttggtccatc ttgacgaacc attgagtaga
     3001 caagcgtggc tcaactacga cacctgtacg ttctgagtga ccaacactgt ggacacgttt
     3061 ttcgattttg acaagggcac cgatttcttc caacttagca acgactgcct tacgagcttc
     3121 aaaacgatcc atgcctgaaa attcaaaggc aagctcattc atagttccgt cgtcgttcat
     3181 gacgttgact tgtggcaagt tatgacgttg gccaaccaag aagtcatttg gatcgtgggc
     3241 aggtgtgatt ttcacgacac cagtaccaaa ctcaggatct gcgtgctcat ctccaacgat
     3301 tgggatgagt ttattagcga ttggaaggat gacgttttta ccaatcaagt ccttgtagcg
     3361 cgggtcttct ggattaaccg caaccgcaac gtccccaaac atagtctcag gacgagttgt
     3421 agcaacttca agggcgcgtg aaccatcttc cagcatgtaa ttcatgtggt agaaggcacc
     3481 ttccacatcc ttgtgaatca cctcaatatc agaaagggct gtgcgagctg ctgggtccca
     3541 gttgatgata aactcaccac ggtagatcca gcctttcttg taaaggttca caaagacctt
     3601 acgaacagct tttgacaaac cttcgtcaag agtgaaacgc tcacgagaat agtctacaga
     3661 gagccccatc ttgccccatt gttccttgat ggtagtggca tattcgtctt tccattccca
     3721 gactttcgtc aagaaagact cacgaccaag gtcatagcgg gaaatgccct caccacgcaa
     3781 gcgctcctca accttagcct gagtggcaat ccctgcgtgg tccatcccag gaagccaaag
     3841 ggtatcaaaa ccttgcatgc gtttttgacg gatgataata tcttgcaaag ttgtatccca
     3901 agcgtgacca aggtggagtt tcccagttac gtttggtggt ggaatcacga ttgaataagg
     3961 cttagccttt tgatcgcctg aaggcttgaa aacatcggca tcaagccatt tttggtaacg
     4021 accagcctca acctcggctg gattgtattt agatgaaagt tctttagaca tgtgtgttct
     4081 ccttaattac ttttattgac aattttaacc aaaccaattt ttgaaagttc aatataaatc
     4141 tcttcaattt cagcaaatgc tgcaagtggt gacatagtat aatttccagg attatattta
     4201 agatcatact tgcttatctt tgaaatataa tacctagagt gtttcaattt taatgattcc
     4261 aactttgatt taatatctac taatgtatta tggtttaact ttaaaaacaa cttattataa
     4321 ttaccataga gctctgtaag agcattaaag tattctttca ctagagctat agcgtcaatc
     4381 ttagatgttt cttggtttag ttttatcaac tcccctttca attttttcca tttaaagttg
     4441 gaatttaaaa gataatctaa atcaatatag aaatctatta taacagtctc atcatctggg
     4501 ctaacagctt ttacctcatt tattggtaag tcagtatgtt gcgaataatt tctcaaagaa
     4561 tggcaaaatc gataagcaaa attggtatca tactgatagc ttgcaaaacc atgtatacaa
     4621 tcaaactcct cactatcttt ggaatatttt tgtttaattt ggttttcgtt aaaatcgaca
     4681 aacaattttc cactggataa taaatgaatc atgaaacgat ttacatctgc ctcttcaatt
     4741 tctaattcct ttgactcaag tttattttta atacttaaaa aaatccgaga catctgaaat
     4801 aaacaattcg aacatattct tgattttttg aaaattcttt tgaatctcaa aaatttggtc
     4861 cgagactgac attatttcct tggttggttc aatatcagag atgacaatac gtttttcatt
     4921 gttgttaatt tctaaataag ctaatcgctc gataatatca ctatcattta attcagcata
     4981 ctcaacatca atttggcgta actgcttctc agatagagag cttacttcct cttttacatc
     5041 gctcatctta ttcctcccac tcgctcttca gcaagccata tatcagactg tcacagcggt
     5101 ttccttgaac atcctttcgg tctcttatgc gagcttcgag ggtaaagcca agcttttccg
     5161 cgactcgttg actttgaagg ttatatccaa agcaagttag ttcaatcttg tgaagaccca
     5221 aatctttaaa ggctaagtca atcaaggcac gcgcagcttc tggcacataa cctcgccccc
     5281 aatagtctga gtgtaaggta tagccgattt ccatcacatc atcttcatgg cgatggttga
     5341 aatagataga gccaacgatc ttatccgttc ctttgacgac aatcccgtag cctgctggga
     5401 gattttcctt ttgattacgc tccggaagaa tgtgctccag ataataaatc tcatcttcca
     5461 aggtcttgac tggaggaaaa cctgctggat aggcgacctc tggcaaacta gcatagtcaa
     5521 agatatcctc agcatccgcc acagtacgga ctcgtaaaac gagacgttct gtttcgattt
     5581 tatctggcag ctcagttctt gccatccttc ttcctcgctt ttttgatgaa actgcccttc
     5641 atatctacac gcttgtccag atagcgataa acgcgctgat atccatctcc catgaaatag
     5701 gttggggcaa acagttgatt tttaaaatgt cccttttcat ccaggagttc tggggcaaca
     5761 agtcgctcaa gaatcttggc aaagatgtgg caaataccgt cttcctcaac aatcctatct
     5821 acccgacaat ctaaaacaag tggacaggcg tctaaaatag gagtctgagt tcgttcagaa
     5881 atttcataat gcactcccaa acgttccaat ttctcctgat gactgataaa accagcctgc
     5941 tccatcgcaa gcatagaagt ttcatcagaa atattcacag taaatttttg atactgtttg
     6001 atctgctctg cggcattctc tctcgcaacg actccaatca caacccaatc tcctagacta
     6061 taagaggaac tacaggtcgt gatgttatag ccaaaattct aatcttgata tcctaaaata
     6121 aaaacaggaa aaccataata tagtttactt gtgttaaaag attgcttcat aacaaccccc
     6181 tttgactaag acgtaaaaga aaagccctgc catctacatg acagggacga atgtgtttat
     6241 ccgcggtacc acccaatttc gggcagttgc ccgcaactct cgtctttaaa gcaaaaagac
     6301 acttttattt caatttttca tccattagca accagttttg acacatttgt ggacttctca
     6361 gcgccgccac tttctgtaaa atgtgggatt caaaacacct ctaatggctc tattgtagca
     6421 agattttttc ggaaatgcaa ggctcaagaa aaattacttg aacttgatgc cattttcttt
     6481 caatttcttg atggtagctg ggccgattcc tttcaagtca aggagttctt tttcagtcca
     6541 gtttttgaaa tgtgaagcag acttgattcc ttcatcatag aaagtcttgg cacgatcaag
     6601 tggaagtcca cccaaatttg ctgcaaaatc ttctacagaa ttagctactt tttgagcttg
     6661 ctctttggta gcttctactg cttgttcaac ttttttagaa acagccttac cagctgcgct
     6721 tgctgactgt tctgcacgct tcacgacttt ttttgtctca tctacaacct tagtcacagt
     6781 acttgaaaag gcacctgcgc gacggaggcc atttcgtaat tgttttttac gattgagttt
     6841 ctttgacatg ataaaatcct ttcaataaaa aatccctgct ctgacaagga tttaacataa
     6901 acattctatc aagattttag tgaaaaatca agaatctttc tcgtttaata atttcgctca
     6961 ccaaacaagc cttctggcaa atcatggaat cccttgccta ctttgaagtt ttcaaactta
     7021 ccaagcaaga actgataagc atccaagcga ctctcgtagc gaatcatggc atctttggca
     7081 cgctcgtcct ggtcttcttc gtaaactttt tgactttcct tgtgcgccat atcgttaatc
     7141 atgatttggg tattgaccca agcttcaaat tccttcataa attcttgttc gtaactcatt
     7201 ttttctcctt attctaatcc acgaaaatag tccgtatcaa tctcacggta gggctggata
     7261 tcctgaacat actccaacac tccttggaat tctccgtctt catcgtgtac tgcagcatag
     7321 gtgatgtgga caaacttacc tcgcgactca gacttgaacc acatttcata cttgtccttg
     7381 gtcccctcac gaagtccctt catgatagcc ttgaccttgt ccaaatactt aggcggatga
     7441 cagagttcga cattgcgccc gacttgggac ggcgtccgtt tgaaaatcat ctcatcagct
     7501 ggcgtattgt cattgtaata ctggaaaata tcttctttat tgacaaaggt aatctccata
     7561 gggagatgat tgaggatgag attggcctgc tcgactgaaa gatagccatt accaaaagcc
     7621 tgttgactat ggcggtccag cacagcttcc ttttccttag gggtaaaggt aatggtaaaa
     7681 tggccttctg gcgtatctat gacttgttga acttgacctt ctgccgtatc tagttgtaca
     7741 ggctcctctg caatcttttc ctcaataaag atctgtcgtt ctggcaccca tttctctgac
     7801 ggacggatga tggcatagcc ataggcatca ctctcctccg caatctgaag ccagtcatcc
     7861 tgagtaaaag actcaaggag aatcatgagc aggatggact cttccttgaa aatcatactt
     7921 tcaaactctg tcgcaaaagc ttcaaaagct tcctttacac tgctaattga cacttctggt
     7981 agtgacttgg ctgtcgttag agctgtttga aagagttccc taatctgatc atccactccc
     8041 cacataactt tgggaggtga atcgtgtcca tagcgctcca tgataggaaa gaagagttct
     8101 tccttacgtt ggtaatggat gtcaaattga cccacaagtc ccatctgacg caccaaaccc
     8161 ttacgcatct ccgccagcat ttcctcgtct tccatagact cataggtatc taacaatcta
     8221 cgaatgcgaa tcaaggccgc acggagagcc agattttctt ctttgaagac acgaactggg
     8281 tgacctggat gctcagtatc tgaaacttcg acacctttga tagcattttt aaaaagattg
     8341 gcatggacat cacagagttc cataacatct tcaaaagtga cgcccgaatc cgagttcatc
     8401 agctcgtgct ccataaggga aatctcaatg gctgagacac ccgcaaaggt cgcatcaaaa
     8461 cgctcctgaa ccgactcagg agaggcgcca ttatgcaatt ctaataaaat atcccgtagg
     8521 acatgaatcc gttcatctgc cattagtcta atccaatcac ttcgtagcca ttcgcttcca
     8581 gtgtgcgtac aatcttgtcc ataggagttc ctgctagctt agaaccctgt ttaagtgata
     8641 ctttacgacc aactgtattg cgcattaagg gattggcaag gggtttaaaa cccaactcca
     8701 ctagaatttc caagacttct ggatgcttgt ccaccacttc tgcaacagga attgacacat
     8761 cgatgatatt gtccatgacg acctccatta tatgttctaa tactcaatga aaatcaaaga
     8821 gcaaactagg aagctagccg caggttgctc aaaacagtgc tttgagattg tagatagaac
     8881 tgacgaagtc agctcaaaac accgttttga ggttgcggat agaactgacg aagtcagtaa
     8941 catatataca gcaaggtgaa gctgacgtgg tttgaagaga ttttcgaaga gtataaaatg
     9001 attttactgc ttatattata ccatatggaa agagaataaa aaactagcag tggagttcct
     9061 gctagttctc tgcgacttgg attaccatct agataagttt aaagaaccaa tccaatatct
     9121 tgtaaaacag caattggact gcaaaagaga tgatcatcca aaagaatttc acaatcccaa
     9181 taatcggttt gataaaaata atggcaagaa gtccccagaa aaatttcatt ttttatcctc
     9241 tggcttaatg agccaccgag ccgtatccat taacttgtcg gcaataaaaa gtttccccag
     9301 accgacaacg gcattatcat ctttctttat cgttttcatt acttttacac cttgcacggt
     9361 caaaaagtaa ttaccataaa ttttagcaaa agctttgata ggattcatat tactctcctt
     9421 tgatgatttc agcctctttt cggattgttt caacatcttc ttgatattga acttcactat
     9481 agttgactag cttggataat tctttctgca agctttcccc cattggtttc atagttgcaa
     9541 aggttaaacc acctgaaatg ataccaccca agataggaat aaatttcccc attcctttgg
     9601 ccagccctcc cttggtaaga ttcacaccaa atattcttaa gactttcttc aaaataggat
     9661 accaaagcgt ctttgttaaa gctttattag gtactgtttt cattacctgt ttggcaattg
     9721 ttataccacc agcacgtagc aaagcagcag ttccattcac ccccaacatg acgcctagat
     9781 aaagcaaaag ggtattttga gcatcttcac tcaactcatc gcgtgaagcc caaagatcct
     9841 cataaccata aatataacct aattcttggg ccaatttcag agagaaacca taaaattgag
     9901 ccacatcagc tggaatggta attgccatag caagccctcc aggtaatcct gccaaaacag
     9961 aagtcccact cgctaataaa acattatccc taatacaggc attagccact cgatctaaga
    10021 tttcttgaga taagagagac gttggacctt gttccaataa ggtaggaatg tcctgtggac
    10081 ccaattcttt ggaaaactta tccactaaaa atttcgaacg atcaacctta acaacaggta
    10141 gtttcaccac ttgttgcaat acttgcatag ctaagtcttg ttcagccata tacaaactcc
    10201 ttatttcttt tttgcacctt atcatattat atttcctaca aaaaaagcat tttctaatta
    10261 gataacatta aaaaatacag aacccctttt ttatagtaaa atgaaacaag aacaggacaa
    10321 atcgatcagg acagtcaaat cgatttctaa caatatttta gaagtagagg cgtactattc
    10381 tagtttcaaa ctattataaa agaatatttt tccatttcaa attcaaccta ttttcctcca
    10441 ccaaaaaagg gctctataat atttgtagtg ggtaaattcc ctatggatat tatggagc
//
LOCUS       DAVMAH010000065        10368 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVMAH010000065 DAVMAH010000000
VERSION     DAVMAH010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10368
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.065"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            221..2881
                     /gene="rrgA"
                     /locus_tag="VYO94_001812"
     CDS             221..2881
                     /gene="rrgA"
                     /locus_tag="VYO94_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus tip adhesin RrgA"
                     /protein_id="HEV1760400.1"
                     /translation="MKKVRKIFQKAVAGLCCISQLTAFSSIVALAETPETSPAIGKVV
                     IKETGEGGALLGDAVFELKNNTDGTTVSQRTEAQTGEAIFSNIKPGTYTLTEAQPPVG
                     YKPSTKQWTVEVEKNGRTTVQGEQVENREEALSDQYPQTGTYPDVQTPYQIIKVDGSE
                     KNGQHKALNPNPYERVIPEGTLSKRIYQVNNLDDNQYGIELTVSGKTVYEQKDKSVPL
                     DVVILLDNSNSMSNIRNKNARRAERAGEATRSLIDKITSDPENRVALVTYASTIFDGT
                     EFTVEKGVADKNGKRLNDSLFWNYDQTSFTTNTKDYSYLKLTNDKNDIVELKNKVPTE
                     AEDHDGNRLMYQFGATFTQKALMKADEILTQQARQNSQKVIFHITDGVPTMSYPINFN
                     HATFAPSYQNQLNAFFSKSPNKDGILLSDFITQATSGEHTIVRGDGQSYQMFTDKTVY
                     EKGAPAAFPVKPEKYSEMKAAGYAVIGDPINGGYIWLNWRESILAYPFNSNTAKITNH
                     GDPTRWYYNGNIAPDGYDVFTVGIGINGDPGTDEATATSFMQSISSKPENYTNVTDTT
                     KILEQLNRYFHTIVTEKKSIENGTITDPMGELIDLQLGTDGRFDPADYTLTANDGSRL
                     ENGQAVGGPQNDGGLLKNAKVLYDTTEKRIRVTGLYLGTDEKVTLTYNVRLNDEFVSN
                     KFYDTNGRTTLHPKEVEQNTVRDFPIPKIRDVRKYPEITISKEKKLGDIEFIKVNKND
                     KKPLRDAVFSLQKQHPDYPDIYGAIDQNGTYQNVRTGEDGKLTFKNLSDGKYRLFENS
                     EPAGYKPVQNKPIVAFQIVNGEVRDVTSIVPQDIPAGYEFTNDKHYITNEPIPPKREY
                     PRTGGIGMLPFYLIGCMMMGGVLLYTRKHP"
     gene            3105..5069
                     /locus_tag="VYO94_001813"
     CDS             3105..5069
                     /locus_tag="VYO94_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEV1760401.1"
                     /translation="MKSINKFLTMLAALLLTASSLFSAATVFAAEQKTKTLTVHKLLM
                     TDQELDAWNSDAITTAGYDGSQNFEQFKQLQGVPQGVTEISGVAFELQSYTGPQGKEQ
                     ENLTNDAVWTAVNKGVTTETGVKFDTEVLQGTYRLVEVRKESTYVGPNGKVLTGMKAV
                     PALIILPLVNQNGVVENAHVYPKNSEDKPTATKTFDTAAGFVDPGEKGLAIGTKVPYI
                     VTTTIPKNSTLATAFWSDEMTEGLDYNGDVVVNYNGQPLDNSHYTLEAGHNGFILKLN
                     EKGLEAINGKDAEATITLKYTATLNALAVADVPEANDVTFHYGNNPGHGNTPKPNKPK
                     NGELTITKTWADAKDAPIAGVEVTFDLVNAQTGEVVKVPGHETGIVLNQTNNWTFTAT
                     GLDNNTEYKFVERTIKGYSADYQTITETGKIAVKNWKDENPEPINPEEPRVKTYGKKF
                     VKVDQKDERLKEAQFVVKNEQGKYLALKSAAQQAVNEKAAAEAKQALDAAIAAYTNAA
                     DKNAAQAVVDAAQKTYNDNYRAARFGYVEVERKEDALVLTSNTDGQFQISGLAAGSYT
                     LEETKAPEGFAKLGDVKFEVGAGSWNQGDFNYLKDVQKNDATKVVNKKITIPQTGGIG
                     TIIFAVAGAVIMGIAVYAYVKNNKDEDQLA"
     gene            5116..6297
                     /gene="rrgC"
                     /locus_tag="VYO94_001814"
     CDS             5116..6297
                     /gene="rrgC"
                     /locus_tag="VYO94_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus minor pilin RrgC"
                     /protein_id="HEV1760402.1"
                     /translation="MISRIFFVMALCFSLVWGAHAVQAQEDHTLVLQLENYQEVVSQL
                     PSRDGHRLQVWKLDDSYSYDNRVQIVRDLHSWDENKLSSFKKTSFEMTFLENQIEVSH
                     IPNGLYYVRSIIQTDAVSYPAEFLFEMTDQTVEPLVIVAKKADTVTTKVKLIKVDQDH
                     NRLEGVGFKLVSVARDGSEKEVPLIGEYRYSSSGQVGRTLYTDKNGEIVVTNLPLGTY
                     RFKEVEPLAGYTVTTMDTDVQLVDHQLVTITVVNQKLPRGNVDFMKVDGRTNTSLQGA
                     MFKVMKEENGHYTPVLQNGKEVVVASGKDGRFRVEGLEYGTYYLWELQAPTGYVQLTS
                     PVSFTIGKDTRKELVTVVKNNKRPRIDVPDTGEETLYILMLVAILLFGSGYYLTKKTN
                     N"
     gene            6636..7538
                     /gene="srtC-1"
                     /locus_tag="VYO94_001815"
     CDS             6636..7538
                     /gene="srtC-1"
                     /locus_tag="VYO94_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-1"
                     /protein_id="HEV1760403.1"
                     /translation="MAKTKKQKRNNLLLGVVFFIGMAVMAYPLVSRLYYRVESNQQIA
                     DFDKEKATLDEADIDERMKLAQAFNDSLNNVVSGDPWSEEMKKKGRAEYARMLEIHER
                     MGHVEIPAIDVDLPVYAGTAEEVLQQGAGHLEGTSLPIGGNSTHAVITAHTGLPTAKM
                     FTDLTKLKVGDKFYVHNIKEVMAYQVDQVKVIEPTNFDDLLIVPGHDYVTLLTCTPYM
                     INTHRLLVRGHRIPYVAEVEEEFIAANKLSHLYRYLFYVAVGLIVILLWIIRRLRKKK
                     KQSEKALKALKAARKEVKVEDGQQ"
     gene            7525..8418
                     /gene="srtC-2"
                     /locus_tag="VYO94_001816"
     CDS             7525..8418
                     /gene="srtC-2"
                     /locus_tag="VYO94_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-2"
                     /protein_id="HEV1760404.1"
                     /translation="MDNSRRSRKKGTKKKKHPLILLLIFLVGFAIAIYPLVSRYYYRI
                     ESNEVIKEFDNTVSKMDKAELEERLRLAQAFNATLKPSEILDPFTDQEKKQGVSEYAN
                     MLKVHERIGYVEIPAIEQEIPMYVGTSEDILQKGAGLLEGASLPVGGENTHTVITAHR
                     GLPTAELFSQLDKMKKGDIFYLHVLDQVLAYQVDQIVTVEPNDFEPVLIQHGQDYATL
                     LTCTPYMINSHRLLVRGKRIPYTAPIAERNRAVRERGQFWLWLLLGAMAVILLLLYRV
                     YRNRRIVKGLEKQLEGRHVKD"
     gene            8405..9256
                     /gene="srtC-3"
                     /locus_tag="VYO94_001817"
     CDS             8405..9256
                     /gene="srtC-3"
                     /locus_tag="VYO94_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-3"
                     /protein_id="HEV1760405.1"
                     /translation="MSRTKLRALLGYLLMLVACLIPIYCFGQMVLQSLGQVKGHATFV
                     KSMTTEMYQEQQNHSLAYNQRLASQNRIVDPFLAEGYEVNYQVSDDPDAVYGYLSIPS
                     LEIMEPVYLGADYHHLGMGLAHVDGTPLPLDGTGIRSVIAGHRAEPSHVFFRHLDQLK
                     VGDALYYDNGQEIVEYQMMDTEIILPSEWEKLESVSSKNIMTLITCDPIPTFNKRLLV
                     NFERVAVYQKSDPQTAAVARVAFTKEGQSVSRVATSQWLYRGLVVLAFLGILFVLWKL
                     ARLLRGK"
     gene            complement(9329..10368)
                     /locus_tag="VYO94_001818"
                     /pseudo
     CDS             complement(9329..10368)
                     /locus_tag="VYO94_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT         3333 a         1721 c         2404 g         2910 t
ORIGIN      
        1 tactatattg tatacaagtg tgtcattgcc aggttgagaa gatagctata acgcactttt
       61 atacgctttt gctacgtttg ttagtgaacg gattaactca gtgagataaa ttttatcaga
      121 acataagtaa tccgtttctt cgtgtataca gattgaaagt acctatgaat catagaagga
      181 ttaacttgtt ctatgaataa tgcttaacag ggagacacac atgaaaaaag taagaaagat
      241 atttcagaag gcagttgcag gactgtgctg tatatctcag ttgacagctt tttcttcgat
      301 agttgcttta gcagaaacgc ctgaaaccag tccagcgata ggaaaagtag tgattaagga
      361 gacaggcgaa ggaggagcgc ttctaggaga tgccgtcttt gagttgaaaa acaatacgga
      421 tggcacaact gtttcgcaaa ggacagaggc gcaaacagga gaagcgatat tttcaaacat
      481 aaaacctggg acatacacct tgacagaagc ccaacctcca gttggttata aaccctctac
      541 taaacaatgg actgttgaag ttgagaagaa tggtcggacg actgtccaag gtgaacaggt
      601 agaaaatcga gaagaggctc tatctgacca gtatccacaa acagggactt atccagatgt
      661 tcaaacacct tatcagatta ttaaggtaga tggttcggaa aaaaacggac agcacaaggc
      721 gttgaatccg aatccatatg aacgtgtgat tccagaaggt acactttcaa agagaattta
      781 tcaagtgaat aatttggatg ataaccaata tggaatcgaa ttgacggtta gtgggaaaac
      841 agtgtatgaa caaaaagata agtctgtgcc gctggatgtc gttatcttgc tcgataactc
      901 aaatagtatg agtaacattc gaaacaagaa tgctcgacgt gcggaaagag ctggtgaggc
      961 gacacgttct cttattgata aaattacatc tgatccagaa aatagggtag cgcttgtgac
     1021 ttatgcttcc actatctttg atgggaccga gtttacagta gaaaaagggg tagcagataa
     1081 aaacggaaaa cgattgaatg attctctttt ttggaattat gatcagacga gttttacaac
     1141 caataccaaa gattatagtt atttaaagct gactaatgat aagaatgaca ttgtagaatt
     1201 aaaaaataag gtacctaccg aggcagaaga ccatgatgga aatagattga tgtaccaatt
     1261 cggtgccact tttactcaga aagctttgat gaaggcagat gagattttga cacaacaagc
     1321 gagacaaaat agtcaaaaag tcattttcca tattacggat ggtgtcccaa ctatgtcgta
     1381 tccgattaat tttaatcatg ctacgtttgc tccatcatat caaaatcaac taaatgcatt
     1441 ttttagtaaa tctcctaata aagatggaat actattaagt gattttatta cgcaagcaac
     1501 tagtggagaa catacaattg tacgcggaga tgggcaaagt taccagatgt ttacagataa
     1561 gacagtttat gaaaaaggtg ctcctgcagc tttcccagtt aaacctgaaa aatattctga
     1621 aatgaaggcg gctggttatg cagttatagg cgatccaatt aatggtggat atatttggct
     1681 taattggaga gagagtattc tggcttatcc gtttaattct aatactgcta aaattaccaa
     1741 tcatggtgac cctacaagat ggtactataa cgggaatatt gctcctgatg ggtatgatgt
     1801 ctttacggta ggtattggta ttaacggaga tcctggtacg gatgaagcaa cggctactag
     1861 ttttatgcaa agtatttcta gtaaacctga aaactatacc aatgttactg acacgacaaa
     1921 aatattggaa cagttgaatc gttatttcca caccatcgta actgaaaaga aatcaattga
     1981 gaatggtacg attacagatc cgatgggtga gttaattgat ttgcaattgg gcacagatgg
     2041 aagatttgat ccagcagatt acactttaac tgcaaacgat ggtagtcgct tggagaatgg
     2101 acaagctgta ggtggtccac aaaatgatgg tggtttgtta aaaaatgcaa aagtgctcta
     2161 tgatacgact gagaaaagga ttcgtgtaac aggtctgtac cttggaacgg atgaaaaagt
     2221 tacgttgacc tacaatgttc gtttgaatga tgagtttgta agcaataaat tttatgatac
     2281 caatggtcga acaaccttac atcctaagga agtagaacag aacacagtgc gcgacttccc
     2341 gattcctaag attcgtgatg tgcggaagta tccagaaatc acaatttcaa aagagaaaaa
     2401 acttggtgac attgagttta ttaaggtcaa taaaaatgat aaaaaaccac tgagagatgc
     2461 ggtctttagt cttcaaaaac aacatccgga ttatccagat atttatggag ctattgatca
     2521 aaatggcact tatcaaaatg tgagaacagg tgaagatggt aagttgacct ttaaaaatct
     2581 gtcagatggg aaatatcgat tatttgaaaa ttctgaacca gctggttata aacccgttca
     2641 aaataagcct atcgttgcct tccaaatagt aaatggagaa gtcagagatg tgacttcaat
     2701 cgttccacaa gatataccag cgggttacga gtttacgaat gataagcact atattaccaa
     2761 tgaacctatt cctccaaaga gagaatatcc tcgaactggt ggtatcggaa tgttgccatt
     2821 ctatctgata ggttgcatga tgatgggagg agttctatta tacacacgga aacatccgta
     2881 aagtgtagaa atgataatat ctatgttctg aacgatactt ttaagaagta gcactcaaga
     2941 agagatttaa gtttacttgg tgaaacctgt tttattcgta agtaaactat cattgaaagg
     3001 ggagatgttt tcgaaaactt gcacagaaaa aggattatta ttgtcatgtg taattcatta
     3061 cattgctcac agttgatttt aagagatatg aataaggaga aatcatgaaa tcaatcaaca
     3121 aatttttaac aatgcttgct gccttattac tgacagcgag tagcctgttt tcagctgcaa
     3181 cagtttttgc ggcggaacaa aaaactaaga cacttacagt tcataaatta ttgatgacag
     3241 atcaagagct tgacgcttgg aattctgatg cgattactac tgcaggttat gacggttcgc
     3301 aaaattttga acagttcaaa caacttcaag gtgttccaca aggagtaacc gaaatctctg
     3361 gtgttgcatt cgagttacag agttatacgg gtcctcaagg aaaagaacaa gaaaatttaa
     3421 cgaatgatgc ggtttggact gcggttaata aaggtgtgac gactgaaacg ggtgttaaat
     3481 ttgatactga agttttacaa gggacatatc gtcttgtcga agtacgtaaa gaatcgactt
     3541 atgtcggtcc aaatggtaaa gttttaacag gtatgaaagc tgttcctgct ttaattattc
     3601 tgccgcttgt aaaccaaaat ggtgttgtag aaaatgcaca tgtctatcca aagaattctg
     3661 aagacaaacc tacagcaacg aaaacatttg atactgcagc aggtttcgta gatccaggtg
     3721 aaaaaggttt agcaattggc actaaggtac cgtatattgt tacaacaact attccgaaaa
     3781 actcaactct tgcaacagct ttctggtcag atgaaatgac agaaggtcta gattataatg
     3841 gtgatgtagt tgttaattat aatggtcaac cgcttgataa ttctcattac acattagaag
     3901 caggtcataa tggctttatc ttgaagttaa atgaaaaagg tctggaagca atcaacggta
     3961 aagatgcaga agcaacaatt acgttgaagt atactgcaac tttaaatgct cttgctgttg
     4021 ctgatgtgcc agaagcgaat gatgtaacat tccattatgg aaacaaccca ggtcatggta
     4081 acactccaaa accaaacaaa cctaaaaacg gtgaacttac aattactaaa acatgggctg
     4141 atgctaaaga tgctcctata gcaggtgtag aagtaacttt tgatttggta aatgctcaga
     4201 caggtgaggt cgttaaagta cctggacatg aaacaggtat tgtattgaat caaacaaata
     4261 attggacatt tactgctaca ggtcttgata ataatacaga atataaattt gttgaacgga
     4321 caattaaggg atattctgca gattaccaaa caattactga aacaggaaaa attgctgtta
     4381 aaaactggaa agatgaaaat ccagaaccaa taaatcctga agagccacgt gtaaaaacat
     4441 atggtaaaaa attcgttaag gttgaccaaa aagacgaacg cttaaaagaa gcacaattcg
     4501 ttgtgaagaa tgagcaaggg aaatatcttg cactcaaatc tgcagcacaa caagctgtaa
     4561 atgagaaagc tgccgcagaa gcgaaacaag cgctagatgc agcgatagca gcctatacaa
     4621 atgctgcaga taaaaatgca gcacaagctg tagtagatgc tgcgcaaaaa acatataatg
     4681 acaattacag agcagctaga tttggctatg tagaagtaga gagaaaagaa gatgcgttag
     4741 ttcttacttc taacactgat ggtcaattcc aaatttcagg tcttgctgct ggaagctaca
     4801 cgttggaaga aacaaaagct ccagaaggct ttgcaaaact tggagatgtg aagtttgagg
     4861 ttggagcagg ttcttggaat caaggtgatt tcaattattt aaaagatgtt cagaagaacg
     4921 acgctacaaa agtagtcaac aaaaaaatca cgatccctca aacgggtggt attggtacaa
     4981 ttatctttgc tgtagcgggg gctgtgatta tgggtattgc agtgtacgca tatgttaaaa
     5041 acaacaaaga tgaggatcaa cttgcttaag taagagagaa aggagccatt gatgacaatg
     5101 cagaaaatgc agaaaatgat tagtcgtatc ttctttgtta tggctctgtg tttttctctt
     5161 gtatggggtg cacatgcagt ccaagcgcaa gaagatcaca cgttggtctt gcaattggag
     5221 aactatcagg aggtggttag tcaattgcca tctcgtgatg gtcatcggtt gcaggtatgg
     5281 aagttggatg attcgtattc ctatgataat cgggtgcaaa ttgtgagaga cttgcattcg
     5341 tgggatgaga ataaactttc ttctttcaaa aagacttcgt ttgagatgac cttccttgag
     5401 aatcagattg aagtatctca tattccaaat ggtctttact atgttcgctc tattatccag
     5461 acggatgcgg tttcttatcc agctgaattt ctttttgaaa tgacagatca gacggtagag
     5521 cctttggtca ttgtagcgaa aaaagcagat acggtgacaa caaaggtgaa gctgataaag
     5581 gtggatcaag accacaatcg cttggagggt gtcggcttta aattggtatc agtagcaaga
     5641 gatggttctg aaaaagaggt tcccttgatt ggagaatacc gttacagttc ttctggtcaa
     5701 gtaggtagaa ctctctatac tgataaaaat ggagagattg ttgtgacaaa tcttcctctt
     5761 gggacctatc gtttcaagga ggtggagcca ctggcaggct atactgttac gacgatggat
     5821 acggatgtcc agttggtaga tcatcagctg gtgacgatta cggttgtcaa tcagaaatta
     5881 ccacgtggca atgttgactt tatgaaggtg gatggtagga ccaatacctc tcttcaaggg
     5941 gcaatgttca aagtcatgaa agaagaaaac ggacactata ctcctgttct tcaaaatggt
     6001 aaggaagtag ttgtggcatc agggaaagat ggtcgtttcc gagtggaagg tctagagtat
     6061 gggacatact atttatggga gctccaagct ccaactggtt atgttcaatt aacatcgcct
     6121 gtttccttta caatcgggaa agatactcgt aaggaactgg taacagtggt taaaaataac
     6181 aagcgaccac ggatcgatgt gccagataca ggggaagaaa ccttgtatat cttgatgctt
     6241 gttgccattt tgttgtttgg tagtggctat tatcttacga aaaaaacaaa taactgatat
     6301 tcaatgtaca tcattatgaa aaagatagca ggctgaaggg aagaccagag tactctgagg
     6361 tgatgttaat caggaatcat ggtgatttgg catgaatcac aataacggat atgaggctgg
     6421 gcagattgtg ccagcctcat tgtgggttat tgtttgtaaa acgataggac tggtctggta
     6481 atcattttag gaatggacag gactgggatt ctgatttaaa atggatggtg aatcagaaag
     6541 aaatgagatt ttctcgtttc tcttagcaga taggattgtc tgttaggaaa agcgataaaa
     6601 tgatgagttt gaagttaaag gaatgctgat aaaaaatggc aaaaacaaaa aagcaaaaac
     6661 gaaacaatct cctattagga gtggtatttt tcattggaat ggcggtaatg gcgtatccgc
     6721 tggtgtctcg cttgtattat cgagtggaat caaatcaaca aattgctgac tttgataagg
     6781 aaaaagcaac gttggatgag gctgacattg atgaacgaat gaaattggca caagccttca
     6841 atgactcttt gaataatgta gtgagtggcg atccttggtc ggaagaaatg aagaaaaaag
     6901 ggcgagcaga gtatgcacgt atgttagaaa tccatgagcg gatgggacat gtggaaatcc
     6961 ctgctattga tgtggatttg ccggtgtatg ctggtactgc tgaagaggta ttgcagcaag
     7021 gggctgggca tctagaggga acttctctac cgatcggagg caattcgact catgcggtga
     7081 ttacggcaca tacaggtctg ccaacggcta agatgtttac ggatttgacc aaacttaaag
     7141 ttggggataa gttttatgtg cacaatatca aggaagtgat ggcctatcaa gtggatcaag
     7201 tgaaggtaat tgagccgacg aactttgatg atttattgat tgtaccaggt catgattatg
     7261 tgaccttgct gacttgtacg ccatacatga tcaataccca tcgtctattg gttcgggggc
     7321 atcggatacc gtacgtagca gaggttgagg aagaatttat tgcggcaaac aaactcagtc
     7381 atctctatcg ctacctgttt tatgtggcag ttggtttgat tgtgattctt ttatggatta
     7441 ttcgacgctt gcgtaagaag aaaaaacaat cggaaaaggc tttgaaggcg ctgaaagcag
     7501 caaggaagga agtgaaggtg gaggatggac aacagtagac gttcacgaaa aaaagggaca
     7561 aaaaagaaga aacatccgct gattcttctt ctgattttct tagtaggatt cgccattgcg
     7621 atatatccat tggtgtcccg ttattattat cgtattgagt cgaacgaggt aatcaaagag
     7681 tttgataata cggtttctaa aatggacaag gcagagcttg aagagcgttt gcgcttggca
     7741 caggctttta atgcgacctt gaaaccctct gaaatcctcg atccttttac agatcaggaa
     7801 aagaaacagg gagtttcaga atatgctaac atgctaaaag ttcatgagcg tatcggatat
     7861 gtagaaattc ctgcgattga acaggaaatc cccatgtatg ttggcacaag tgaagacatt
     7921 cttcagaaag gggcagggct gttagaaggg gcttcgctgc ctgttggagg tgaaaatacc
     7981 catacagtga tcactgctca cagaggattg ccaacggcag aattgttcag tcaattggat
     8041 aagatgaaga aaggggatat cttttatctt cacgttttag accaggtttt ggcctatcaa
     8101 gtggatcaga tagtgacggt ggagccgaat gattttgagc ctgttctgat tcaacatgga
     8161 caagattatg cgactttact gacttgtacg ccatacatga ttaacagcca ccgtttgttg
     8221 gtacgtggga aacggattcc atatacagcg ccgattgctg agcggaatcg agcggtgaga
     8281 gagcgtgggc aattctggtt gtggttatta ctaggagcga tggcggtcat ccttctcttg
     8341 ctgtatcgcg tgtatcgtaa tcgacggatt gtcaaaggac tagaaaagca attggagggg
     8401 cgtcatgtca aggactaaac tacgagcctt attgggatac ttgttgatgt tggtagcctg
     8461 tttgattcct atttattgtt ttggacagat ggtgttgcag tctcttggac aggtgaaagg
     8521 tcatgctaca tttgtgaaat ccatgacaac tgaaatgtac caagaacaac agaaccattc
     8581 tctcgcctac aatcaacgct tggcttcgca aaatcgcatt gtagatcctt ttttggcgga
     8641 gggatatgag gtcaattacc aagtgtctga cgaccctgat gcagtctatg gttacttgtc
     8701 tattccaagt ttggaaatca tggagccggt ttatttggga gcagattatc atcatttagg
     8761 gatgggcttg gctcatgtgg atggtacacc gctgcctctg gatggtacag ggattcgctc
     8821 agtgattgct gggcaccgtg cagagccaag ccatgtcttt ttccgccatt tggatcagct
     8881 aaaagttgga gatgctcttt attatgataa tggccaggaa attgtagaat atcagatgat
     8941 ggacacagag attattttac cgtcggaatg ggaaaaatta gaatcggtta gctctaaaaa
     9001 tatcatgacc ttgataacct gcgatccgat tcctaccttt aataaacgct tattagtgaa
     9061 ttttgaacga gtcgctgttt atcaaaaatc agatccacaa acagctgcag ttgcgagggt
     9121 tgcttttacg aaagaaggac aatctgtatc gcgtgttgca acctctcaat ggttgtaccg
     9181 tgggctagtg gtactggcat ttctgggaat cctgtttgtt ttgtggaagc tagcacgttt
     9241 actacgaggg aaataaaaag aaatgaaagg aaagctaagg ctgttccttt ttccggctct
     9301 ttgtcaactg tagtgggttg aaaaaaagct aagctcgaga aaggacaaat tttgtccttt
     9361 cttttttgat attcagagcg ataaaaatcc gttttttgaa gttttcaaag tttcgaaaac
     9421 caaaggcatt gcgcttgata agtttgatga gattattggt cgcttccagt ttggcattag
     9481 aatagtgtag ttgaagggcg ttgataatct tttctttatc tttgaggaag gttttaaaga
     9541 cagtctgaaa aataggatga acctgcttaa gattgtcctc aataagtccg aaaaatttct
     9601 ctggttcctt attctggaag tgaaaaagca agagctgata gagttgatag tggtgtttca
     9661 agtcttccga atagctcaaa agcttgttta aaatctcttt attggttaag tgcatacgaa
     9721 aaataggacg ataaaatcgc ttatcactca gtttacagct atcctgttaa tgagtttcca
     9781 gtagcgcttg atagccttgt attcatggga ttttcgatga aactgattca tgatttggac
     9841 acgcacacga ctcatagcac ggctaagatg ttgtacaata tgaaagcagt caagaacgat
     9901 tttagcatta ggagactgtt tcagcctgag cctagaaatt tgaaagcgaa gctgtttagc
     9961 caagtcatag taagggctaa acatatccat agtaatgatt ttgacgcgga catcggacgg
    10021 ctctatcata tttaagaaag tgatctcgga tgacagcttg tgttctacct tcaagaacag
    10081 tgatgatatt gagattgtta aaatcttgcg caataaagct catctccatc tcccgattga
    10141 aacagtcact ccccggactg tttcaacgtc ccaggacata atctcaggaa gacgcgaaaa
    10201 atcatgctca aagtgagaat cattgagctt gcgaatgaca gttgaagttg aaatggccag
    10261 ctgatgagca atatcggtca tagaaatctt ctcaatcaac ttttgcgcaa ttttttggtt
    10321 gataatacga ggaatttgat gattcttctt gacgatagaa gtttcagc
//
LOCUS       DAVMAH010000066        10326 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVMAH010000066 DAVMAH010000000
VERSION     DAVMAH010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.066"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..338
                     /locus_tag="VYO94_001819"
     CDS             <1..338
                     /locus_tag="VYO94_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1760406.1"
                     /translation="VSGNKGQKNNIELIAKQRSFIDYWAKYVSYLPFPTPEFFLANLC
                     NSVDREGYDFSKDGNGKEYFRKKTQVALGIENITSEDIFQEQRRAVSKIQPESSMFQC
                     IKEKLEALF"
     gene            718..1521
                     /locus_tag="VYO94_001820"
     CDS             718..1521
                     /locus_tag="VYO94_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV1760407.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1637..2907)
                     /locus_tag="VYO94_001821"
                     /pseudo
     CDS             complement(1637..2907)
                     /locus_tag="VYO94_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            3156..5744
                     /locus_tag="VYO94_001822"
                     /pseudo
     CDS             3156..5744
                     /locus_tag="VYO94_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            6044..6883
                     /locus_tag="VYO94_001823"
     CDS             6044..6883
                     /locus_tag="VYO94_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV1760408.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            6901..8739
                     /locus_tag="VYO94_001824"
     CDS             6901..8739
                     /locus_tag="VYO94_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1760409.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            8752..10167
                     /locus_tag="VYO94_001825"
     CDS             8752..10167
                     /locus_tag="VYO94_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1760410.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
BASE COUNT         3291 a         1530 c         2054 g         3451 t
ORIGIN      
        1 atgtttcagg taataaaggg caaaaaaata atattgaatt aattgcgaaa caaagaagct
       61 ttatagatta ttgggctaaa tacgtttctt atcttccttt cccaacccca gagttttttt
      121 tagctaattt gtgtaacagc gtagataggg aaggttatga tttttctaaa gatggcaacg
      181 gaaaagaata ttttagaaaa aaaactcaag tagcgttagg aatagagaat ataacttctg
      241 aagatatttt ccaggagcaa agaagagctg tttcaaaaat acagccagaa tcatcaatgt
      301 ttcagtgtat taaagaaaaa ttagaggcat tgttctaatt ccttagatta ggtactacat
      361 aacaaatttt ttaaattcaa acccgcacca aaaacaacat tgcaactttc ttctcaggta
      421 atgtgttggg atttgaacag accaacgagt tcatagaggt gtatgccaat gagtttgata
      481 agtatgcgcg tcagacttat tagttcattt atccagatat atctcgataa tcatattatt
      541 tagtcaaaga acatcccata tgagggcatg aaatgctaag tttagcttgc tcactattaa
      601 gatgaagtat atatatttca tagaacttat tgtgaaggat ttttataatt ttcgccaatt
      661 ccatacccat ttcaccattt accgatgaca cagaaaaaca attgaaagga tatttctatg
      721 caaccaactt acaacattga caatccaaac ttgtcttatg aagcgaagcg tgatttatgg
      781 cggataggtt ttggtctgca gaaagttgac aatctagtgc catcagcgta tatggaatct
      841 ttggctgaga aacagtcccg gggagaactg acttatgagc aggtttatga ggatgcaacg
      901 gcttatcacc atactattga tgcaagtacg gaagaggcag acttggtttc tctacgtatt
      961 gtagaactat tgtctcgaag aggctttagc tttagtcctg cgaccttact tgctattcat
     1021 aaggagttgt ttcaagatat atttgaaccc tctattccgg tggggcaatt tcgtcagacc
     1081 aatatcacaa agaatgaacc tgttttgaat ggtgaaagtg ttgtgtactc tgattactcc
     1141 atgattcaaa tgaccttgga ttatgatttt aatcaggaaa aacaagttgc atatgcgaca
     1201 ctaactcagg cggatgtggt taaacaaatc cagcatttta tttcaggaat ctggcagatt
     1261 catccatttc gcgaaggcaa cactcggaca gtaacggtct ttttgattca gtatcttcgt
     1321 gagtttggtt ttgatattga taatatacca tttcagcaac attccaagta ttttcgtgat
     1381 gccttggtat tagataatgc aaagatttta cagcgacgtc ctgagttttt aacagctttt
     1441 tttgaaaatc tcttgctcgg tggtcaaaat gatttgtctt cagaaaaaat gtatctagat
     1501 ttagaccttg atttttcata atccaaatac tgagtaaaca ttgaatttta ggcaaaaatg
     1561 aagtaaatat tctcacaaga aaacgtatat catcaaagtt ttaggtgtac tgaccccaaa
     1621 cagttagaca attaatttat ccgaaggatt tagttctgta ttgcacaggg ataagtcctt
     1681 ttagttttac cttaattcgt ttattgttgt agtaatcaat atagtctaca atagcttgtt
     1741 ccaattgctt aagcgactga aacgacttct cataaccgta aaacatttcc gatttcagaa
     1801 tcccaaagaa agattccatc ataccgttgt cttggctgtt tcccttgcgt gacatagatg
     1861 cttgaattcc cttaccctca agaaactgat gataagaatc gtgttgatat tgccagcctt
     1921 ggtcactatg gagaatcgta ttctcgtagt gcttctctgt gaatgcctgt tccaacattg
     1981 tttgtacttg ttctaagttg ggtgaagttg aaagattata ggcgataatt tcgctattaa
     2041 agccatctaa aactggtgat aagtaaagct tttgagtact tgctggaatg gcaaattctg
     2101 tcacatctgt gtagcactgt tccattgttt tagagccttc aaattggcct tgaatgagat
     2161 tctctgcctt cttgccaacg tctcctttat gagaagaata ttttcgtttc tgtcgcattt
     2221 tagcttgtaa attgagtact tcatcaagtg ttgaactctt ttatgattta ccagataacc
     2281 acgatttctt agttctaaat aaatccgacg ataaccataa tttcccttgt gttcgataaa
     2341 aatggattga atttcagctt taagctcttg gtccttatct gttttatcta gctgtttcaa
     2401 gtgatagtag taggtcgaac gagctagttt aatggctttt agaagaagat ctaacgaaaa
     2461 ctcagtcatt aattcttgaa caatttctgt ctttcttctt tctctttttt ctccttcaat
     2521 cggagttctc ttaacttttt taggatggca ttctccgctc tcaggtactc tccctcttgt
     2581 tttctcaaca atagtatacc cgtttttcct gtattgtgct agccagttaa gaagtatcgt
     2641 acgacttggg agaccgtatt caagagaaac tctatcttta gtccagcctt catgtcagac
     2701 tttattaatc atttcttgtt ttaaatcagg agaatagtaa cgattttttc cttttttgac
     2761 gaactctatt ccgtaacgat caatcaattt aatcatgtac ctaagattag aattgtttat
     2821 cccaaattta tttgaaagct tctctaagct atatccttgt tttctaagtt catagatctg
     2881 aactttatca tcataagtta atttcataat aaaaacaccc caaaaagtta gattttttct
     2941 gtctaacttt tggggtgtag ttcaaaacaa ccttggtaat atgcgttttt tgaattttat
     3001 agactgctcg tttaaactct atttacctcg tacattccgg agcgagatgg actattagtc
     3061 gcatacaaaa tgagtgctat tcggatttta ttttcgtgta caatttcagc tattcttgtt
     3121 ataatcagcc tataggaatc aaggaggtga ctcttatggc tgtttttgtg tctttggatg
     3181 gaattgtggt agaagtactt gatgtctttt cttcttttga tggggatagt gagtttttct
     3241 tgtgtaaacg tcttaaagac aagagtcagt ttgttatgga acgctctcag ttcgaggaga
     3301 tgttccaact tcaaagtagt cgcttgacga cgcaagaaaa attacaattg tttacctctg
     3361 tgtttgctgg ccgttatgat gtttatgcta agagttttat caatgatcaa gagaaaattc
     3421 agtattttcc ttcctatgat tatggttgga agcagttgct acctgaaaaa cggagtttcc
     3481 agacattgac ggattccgtt ttgaaatctc attttcgtgg ggagacagct atcggtatct
     3541 ttcctatgca cttagatgat agctgtcatt ttttggtact ggattttgat gaaggagatt
     3601 ggaaagaagc tggtttaacc attcgaagaa tagccaggga acgccagatg gaagcccatt
     3661 tagagatttc tcgttcgggt tacggactcc atatttggtt cttctttgag gaagcgattc
     3721 tgagtcgaaa ggctcgtctg tttggaaaga aactattaga attggctatg caggaaagta
     3781 tgcaactgtc ctttgattct tttgatcgca tgtttccaaa tcaggatgtt cttcctaaag
     3841 gtggatttgg taatttaatt tcctttcctt ttcaaggaga agcttatcat caagggcgaa
     3901 cggtccttgt ggatgaacat tttcaacctt atggagacca atggaggtat ctgcaaggaa
     3961 ttcagaagat ttcaactgct aaagtggcac tgttaatcca agaggagtta ggcaagcaag
     4021 aattggataa ggagttgaag gtcgttttat ccaatatgat ccaacttaaa aaatcgtctg
     4081 tgacacccaa gacactgttt ttcttgaaaa atatggcttc attttctaat cccgaatttt
     4141 atttaaagca ggctatgcga cagccaaact atcaaattcc tgagcgaatg tatttatttg
     4201 gagaatccga ttattattta tggctgccaa gaggcttgtt atatccattg caagataaat
     4261 ttaagcaggt agttgtggag gataggagaa aagtacaaag gtctattaga gtagcattta
     4321 agggagaact cacttttgag caagagttag ccctgtcaga tatgaattct aaagaaaatg
     4381 gtttacttca tgcgggacag gttttggaaa gagcgtttta ggtgctgctc ttatctctga
     4441 acgtaagaca aaaaccatta tcctagttca taataggcaa ctcttagacc aatgactgga
     4501 tcgtttaaag tgttttttga ctttcgaaga ggcagaagct acccgttata caccatcagg
     4561 tcgtgaaagg gtaataggct atgtcgggca gtacggtggg gctaagaaat gactgagtaa
     4621 actggttgat gttgttatga ttcaatctct atttaagttg gaaaatagtc aaagtctttt
     4681 ggatgagtat gagatgatga ttgtggatga gtgtcatcat atctctgcct tgatgtttga
     4741 aaaagttgtt gctcagttta gagggaagta tctttacggt ttgacggcta cgcctgagcg
     4801 taagaatggt catgaaccta ttgtttttca gagaaattga aaagaccaaa gcaagtaatt
     4861 ttatacagcc cagtgattgg attgctacag actcagcgag gaatcagttg attctcaagg
     4921 atattctagc ccaagtggca gaaggacgga atatcttggt tttagttaat cgaattcaac
     4981 agatagatgt ctttgaaaag ttattgaaag agaaagaggt tgatgactgt tacattatta
     5041 gcggaaaaac caaagtccga gaaagaacga gtttactgga gacgttagaa cagttagata
     5101 aagggtttgt tttgttgtct actggaaaat acattggcga aggttttgac ttacctcagt
     5161 tggacacgct tatcttggca gcaccctttt cttggaaaaa taatttaatt cagtatgcag
     5221 gtcggattca tagaaactac aaggataagt ctttggtgcg tattttcgat tatgtggata
     5281 ttcatgttcc ttatttagaa aagatgtttc agaaacgaca agtagcttat cgaaagatgg
     5341 attatcgtgt catcgagggt gaggagaaac aattcgttta tgttgatagt agatatgaga
     5401 aggtgttgag agaggactta gcaggggaaa gacaggaatg tctgcttatt ttaccttatg
     5461 tgcaccagac aaaactgatg aattttctaa aagaatttag gattagtcaa attgagatat
     5521 gtataccaga gacggttgca aataaagcat ggctagacca gttgaagagc cagaaaatta
     5581 aagtgtcttt tactcaatca aaaatagtaa cgcctattct tttggtgaat aagactattg
     5641 tttggtatgg tgcaatgcca ttattaggga aggtagatga gatgaccata ttacgtttgg
     5701 aatcagctag tatagtttct gaactagtgg caggtttacg atagagaaaa tttttaaaaa
     5761 tttctatgta tgattttcat ttctttagtg agactgttgc cattatcaca ttcgaatcac
     5821 acaaaataaa aaaattttta taagtacttg acaaatagat tgaaatatca taaaatgaaa
     5881 atggttacag agttattaat tatttaagct tcatgtcacc attaaaaatt gaaataaaag
     5941 gatgttatca ctaatacaag tgagcaggaa cctatttaat cacatcggaa gaagtttctt
     6001 gatgttttta agtaggttcc ttttatttta aaagggaaat tttatgatca taaaacgaat
     6061 actaaaccac aatgccgtaa ttgcgcaaag taaaaaagat atcgatattc ttctttttgg
     6121 aaggggcata gcttttggaa gaaaaactgg agataaagta aatccaattg atattgagaa
     6181 aagttttttt ctcaaaaata gagataatat gacccgtttt acagagatgt ttattaacgt
     6241 tcctttggag ttggtgtaca tcaccgaaaa aataattaac ctaggtaaaa taacattggg
     6301 taataatttt gatgaaatta tctatattaa tttaacggat catatttctt cgagcataga
     6361 acgttataaa gaagggatta ttatttcgaa tcccctacgc tgggaaatat cgaaatatta
     6421 taaagaagaa tttgaacttg ggaaaagggc tttacaaata ataaaaaaag agttaggtat
     6481 tgaacttcca attgacgaag ctgcattcat agcgctacat tttgttaatg ctaatttaga
     6541 aaataatttt caagagtcgt ataaaatcac tgaaataatt atgggaattg agaaaatcat
     6601 tcaagatttc tattgtactg agtttaacca agattctatt gattattata gattcataac
     6661 tcatataaaa ttatttgccc atcgcttggt tgaaaataca acttattgtg acgatgatga
     6721 tgaagacttg ttagcattaa tgaaaaataa atatcctaga gaatatgaat gtggtgaaca
     6781 ggtggcaatg tttatacaaa ctgagtacaa ttatttgctg acttctagtg aattagttta
     6841 tttgatggct catattcgtc gcttaacaaa aaatttagat taatagaata ggagaatacc
     6901 atgagttata aagatacggt acaaaaaatc ctcgatgtaa ttggaggtga aaaaaatgtc
     6961 aatagagtta cccattgtgt aacacgttta agattagaat taaaagatga aaatttagtc
     7021 aatgatgatg atgtgaagaa gataccaggt gtaataggta ttatgaaaaa gaatggacaa
     7081 tatcaaatta tacttggtaa tgatgtagct aattattata aagaattcgt taaacttggc
     7141 aattttgaat ccgattcagt tgttcaaggg cacaaaggga atattttaga aagaatcatt
     7201 gagtatatcg ctggttccat gactccaatc attccagcaa tgttaggggg aggtatgttg
     7261 aaagtcttgg taatcatttt accaatgctt ggtatattgc aatcagattc tcagactatt
     7321 gcttttttga cattttttgg ggatgctcca tattatttct taccgctgtt attagcttat
     7381 tctgcatcac aaaaattaaa agtaacatct acattagcta tgtctgtagc aggtgtactt
     7441 ctccatccaa attttgttca aatggtgcaa tcagggaatc ctcttagttt atttggtgca
     7501 cctgtgacac cagctagtta tggttcatca gtcgttccaa ttcttattat ggtttggttg
     7561 atgaaatata ttgaaaaaat aattgctaaa ttaacaccag ctattactaa gagttttttg
     7621 caacctacgc tagtattatt agtatcaagc tgtattgcct tagttgtagt cggacctatt
     7681 ggagtaattg ttggtgaagg attatcaaat ctagttgggc aaatgtatgg tgtagctgga
     7741 tggcttacat tagctattct tggtgctatt atgccattta ttgttatgac tggaatgcat
     7801 tgggcttttg cacctatttt tttggcggca tctattgcta ctccagacgt attaattctt
     7861 ccagcaatgt tagggtcaaa cttagctcaa ggggctgctt cgatggctgt tgcattaaag
     7921 agtaaaaata ataatacaaa acaaattgct tttgcagcag gtttctcagc cttacttgca
     7981 gggattaccg aacctgcatt atatggtgtg actttaaaat ataaaaaacc gctttatgca
     8041 gctatgattg gtggtggatt agcgggatta tttgcaggtc ttactagtgt taaagcatat
     8101 ctatttgctg tcccatcttt gatagcgttg cctcaattta tttattctga tgtgccatca
     8161 aatattgtaa atgctttaat tgtggcggtc atttcggttg ttattacctt tgtattagct
     8221 tatatatttg gaatcgatga agaagagagt tctagcaatt tagaagttaa agctggagtt
     8281 tcaaataaaa aaatgatatt ttctcctata tcaggagaaa tcattccgtt aagcgatgtc
     8341 caggataaaa cattttcaga taaactaatt ggagacggag tagcgattat tccaagtgaa
     8401 ggtaaggttt atgcaccatt tgatgggaaa attacaaata tttttccgac taagcacgca
     8461 attggattga agagtgatga gggtgttgaa ttactaattc atattggatt agatactgtt
     8521 gagctaaaag gtcaaggttt tattagtcat gtagaagaag gagacagagt tttcaaaaat
     8581 cagttgattt ttgaaatgga cttgaattta atcaagacta aaggctacga aacagttaca
     8641 ccagtaattg taacgaatac caatgatttt ctagatgtat tagtattacc taataatcag
     8701 acaatcgagc attctaagga attactggta atattataat ggaggaaagt tatgaccatt
     8761 tttccagatg attttctttg gggtggagct gttgcagcta atcaagtaga gggagcatat
     8821 aatgaagatg gtaagggctt atcagttcag gatgtgttac ccaaaggtgg attaggagaa
     8881 gcaacagaaa atcctacaga agataactta aaattgatag gtattgattt ttatcataaa
     8941 tataaggaag atatatcctt gttttctgaa atgggcttta atgtttttcg tacttctatt
     9001 gcatggagta gaatttttcc aaaaggagat gaggaagaac ctaacgaagc tgggttgaaa
     9061 tattatgatg aattgtttga tgaactacat gctcacggga tagaaccact tgtaactctt
     9121 tcacactatg agactccatt atatttagca agaaaatatc atggatggat tgataggaga
     9181 atgattcatt tttatgaaaa atttgctcga acagttttag aaaggtataa agataaagtt
     9241 aaatattggc ttacatttaa cgaagtaaac tctgttttgg aattaccgtt tactagtgga
     9301 ggaatagata tacctaagga gaatctttcg aaacaagaat tatatcaagc tatacatcat
     9361 gaattagtcg cctcgagttt ggttacaaaa attgctcgtg agattaattc agagtttaag
     9421 gtggggtgta tggtattagc tatgccagct tatccaatga ctccaaatcc aaaagatgta
     9481 tgggcgactc atgagtatga gaatctaaat tatctatttt cagatgtgca tgttagaggt
     9541 tattatccga attatgcaaa aagatatttt aaggaaaatg acattaacat agagtttgca
     9601 gctgaagatg cagagttatt aaaaaattat actgtagatt ttttatcctt tagctattac
     9661 atgagtgtga ctcaatctgc tcttccaaca cagtataatt caggagaagg gaatattatt
     9721 ggtggtttag taaatcctta tttagagtct tctgagtggg gatggcaaat tgatccaatt
     9781 ggactacgta taattttaaa tagatattat gaccgttatc aaattccatt atttatagtg
     9841 gaaaacggat taggtgctaa agatcaacta ataaaagatg aatttaataa cttaacagtc
     9901 caagatgatt atagaattca gtatatgaaa gaacatttat tgcaagtagc tgaagctcta
     9961 caagatggtg tggaaattat gggctatacg tcttggggat gtattgactg cgtttctatg
    10021 tccactgcac aactttctaa gaggtacggt ctcatttatg ttgatcgaaa tgatgatgga
    10081 aatggcacat tcaatcgata taagaaaatg tcctttactt ggtataaagg agtgattgaa
    10141 tcaaatggag aatccttatt caaatagttt gtttattgat gattagatat tatcacggtt
    10201 aaggcaacat ctcattaaat atgaaataaa gaggtttgga agacatcaaa ttctaaacct
    10261 ctttatttta tagggggatt aattaattta attttgttac agagagccga ttataaatag
    10321 ttaact
//
LOCUS       DAVMAH010000067        10306 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVMAH010000067 DAVMAH010000000
VERSION     DAVMAH010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10306
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.067"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            89..1264
                     /gene="mutY"
                     /locus_tag="VYO94_001826"
     CDS             89..1264
                     /gene="mutY"
                     /locus_tag="VYO94_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV1760411.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1319..2023
                     /locus_tag="VYO94_001827"
     CDS             1319..2023
                     /locus_tag="VYO94_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1760412.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2016..3365
                     /gene="vicK"
                     /locus_tag="VYO94_001828"
     CDS             2016..3365
                     /gene="vicK"
                     /locus_tag="VYO94_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV1760413.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3367..4176
                     /locus_tag="VYO94_001829"
     CDS             3367..4176
                     /locus_tag="VYO94_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1760414.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4267..4509
                     /locus_tag="VYO94_001830"
     CDS             4267..4509
                     /locus_tag="VYO94_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV1760415.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4511..4765
                     /locus_tag="VYO94_001831"
     CDS             4511..4765
                     /locus_tag="VYO94_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1760416.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4812..5585
                     /locus_tag="VYO94_001832"
     CDS             4812..5585
                     /locus_tag="VYO94_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEV1760417.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(5848..6834)
                     /locus_tag="VYO94_001833"
     CDS             complement(5848..6834)
                     /locus_tag="VYO94_001833"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV1760418.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7028..9496
                     /gene="gyrA"
                     /locus_tag="VYO94_001834"
     CDS             7028..9496
                     /gene="gyrA"
                     /locus_tag="VYO94_001834"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV1760419.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYDIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGFLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9496..10239
                     /gene="srtA"
                     /locus_tag="VYO94_001835"
     CDS             9496..10239
                     /gene="srtA"
                     /locus_tag="VYO94_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV1760420.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         3190 a         1744 c         2306 g         3066 t
ORIGIN      
        1 agtagataga aaagttatat actatctatt gaaaatatta taaatcagat acaaagacag
       61 gtgaaacctt ctgtgttata ctagagatat gttagatttg aaagaatacg gtatcgtcat
      121 gtggccggag gagaaagtca tttctttccg tgagaaactt ctcgcttggt atgatgaaaa
      181 caaaagagat ttgccttgga ggagaagtaa aaatccttat cacatctggg tatctgaaat
      241 catgcttcag cagaccaggg tggatacagt tatcccttac tacgaaagat tcctggactg
      301 gtttccaact gtcgaaagtc tggcaactgc gcctgaggag agtttactga aagcttggga
      361 gggcttgggc tattattctc gagttcgcaa tatgcaggct gcagcccagc agattatgac
      421 tgactttggt ggccaatttc caaataccta tgaaggaatt tccagcttga aagggattgg
      481 accttacaca gcaggagcca tttccagtat tgcttttaac ttgcctgagc cagctgtaga
      541 tggtaatgtc atgcgggtct tggcgcgtct gtttgaagtc aaccacgata ttgggattcc
      601 aagtaatcga aaaatttttc aggcaatgat ggagatcttg attaatccgg atcgtccggg
      661 tgattttaat caagccttga tggacttagg gtctgatatt gagtctcctg taaatcccag
      721 acctgaagaa agtccagtca aggactttag tgcggcatat cagaatggaa ccatggaccg
      781 ttatccaatt aaatctccta agaaaaagcc ggttcctatt tatcttaaag ccttagttgt
      841 gaaaaattct caaggacaat ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg
      901 tttttggcat ttccccttta tagaagttga taacttttcg caagaagagc agtttgacct
      961 ctttcatcag gttgcggaag aaagtgtgaa ctttggcccc agtccagaag agagtttcca
     1021 gcaggactat gacctagatg ttgattggct tgatgtttgt tttgatacag tccagcatgt
     1081 ttttagtcat cgaaaatggc atgtacagat tgtagcaggt caggtgagtg acttccatga
     1141 tttttcagat agggaagttc gttggctttc accagaagaa ttcaagaatt acccacttgc
     1201 caaaccccaa caaaaaatct ggcaggctta tgcacaagcc aacttagaca gtagccaaga
     1261 ctagctattg tgtcttctga ctattttttg gtataatagt agagaaaaag gtgaacatat
     1321 gaaaaaaata ctaattgtag atgatgagaa accaatctcg gatattatca agtttaatat
     1381 gaccaaggaa ggttacgaag ttgtaactgc ttttaatggt cgtgaagcgc tagagcaatt
     1441 tgaagcagag caaccagata ttattattct ggatttgatg cttccagaaa ttgatggttt
     1501 agaagttgct aagaccattc gtaagacaag cagtgtgccc attcttatgc tttcagccaa
     1561 agatagtgaa tttgataagg ttatcggttt ggaacttggg gcagatgact atgtaacgaa
     1621 acccttctcc aatcgtgagt tgcaggcgcg tgttaaagct cttctgcgtc gttctcaacc
     1681 tatgccagta gatggtcagg aagcagatag taaacctcaa cctatccaaa ttggggattt
     1741 agaaattgtt ccagacgcct acgtggctaa aaaatatggc gaagaactag acttaaccca
     1801 tcgtgaattt gagcttttgt atcatttagc atcgcataca ggtcaagtca tcacgcgcga
     1861 acacttgctt gagactgtct ggggttatga ctattttggt gatgtccgta cagttgatgt
     1921 gactgtacga cgtctgcgtg agaagattga agatacgccc agccgaccag agtatatctt
     1981 gacgcgccgt ggtgtagggt attacatgag aaataatgct tgatttactg aaacaaacca
     2041 tttttaccag agattttatc tttatcctga ttttgttagg tttcatcctt gttgtgaccc
     2101 tcttattact ggaaaataga cgtgataata ttcagttgaa gcaaatcaat caaaaggtta
     2161 aagatttgat tgcaggagat tattccaagg ttcttgatat gcaaggtggg tctgaaatca
     2221 ccaatattac caataatttg aatgacttgt cggaggttat tcgtctcact caggaaaatc
     2281 tagaacaaga gagtaagagg ctaaatagta ttctgtttta tatgacagat ggggttcttg
     2341 cgaccaaccg tcggggtcag attatcatga ttaacgatac agccaagaag caactggggt
     2401 tggttaagga agatgttctg aatagaagca ttttggaatt gctcaagata gaagaaaact
     2461 atgaattgcg tgatttgatt acccaaagtc cagaattgtt gctagattcc caagatatca
     2521 atggcgaata tttgaacctt cgagttcgct ttgccttgat acgtcgagag tctggcttta
     2581 tttcaggttt ggtggctgtt ttgcatgata cgacggagca ggagaaggaa gaacgcgaac
     2641 gaagactctt tgtttccaat gttagccatg agttacggac tcctctgact agcgtaaaat
     2701 cctatcttga agccttggat gagggggctt tgtgtgaaac tgtagcacca gactttatca
     2761 aggtttctct tgatgagacc aaccgtatga tgcgcatggt gacggatctc ctccatcttt
     2821 cacgtattga taatgctacc agtcacctag atgtggaact gattaacttc actgctttta
     2881 ttacctttat cctcaatcgt tttgacaaga tgaaaggaca ggaaaaggag aaaaaatatg
     2941 agttggtgag agattatccc atcaattcta tctggatgga aattgataca gataagatga
     3001 cgcaggttgt cgacaatatt ttaaataatg ctattaagta ttcgccagat gggggtaaaa
     3061 tcactgtcag aatgaagaca actgaagacc agatgatttt atccatttct gaccacggtt
     3121 tggggattcc taagcaggat ttaccacgta tctttgaccg tttctatcgt gtggatcgtg
     3181 ctagaagtcg tgcacaaggt ggtacaggtc taggactgtc tatcgctaaa gaaattatca
     3241 aacaacataa gggctttatt tgggccaaga gtgaatacgg caagggttca acctttacca
     3301 ttgtgctccc ttatgataag gatgcagtga aagaagaagt atgggaggat gaagtagaag
     3361 actagaatga gtgaaatagg ctttaaatac agtattttag cgtcgggttc cagtggaaat
     3421 tctttttatc tggaaacctc aaaaaagaag cttttagtag atgcaggctt gtctggcaag
     3481 aaaattacca gtctgctagc tgaaattaac cgtaagccag aagacctgga tgccatcttg
     3541 attacccatg agcattcaga tcatatccat ggagtaggcg ttttggctcg caagtatggt
     3601 atggatcttt atgccaatga aaagacctgg caagctatgg aaaatagtaa atatcttggc
     3661 aaggtggatt cttcgcaaaa gcatattttt gaaatgggta aaaccaaaac ctttggagat
     3721 atcgacatcg agagttttgg tgtaagccat gatgcagtcg caccgcagtt ctatcgcttt
     3781 atgaaggatg ataagagttt tgtccttttg acagatacag gttatgtcag tgaccgtatg
     3841 gcgggcattg tcgaaaatgc ggatggctat cttatcgagg ccaaccatga tgtagagatt
     3901 ttgcgatcag gttcttacgc ttggcgactc aaacaacgaa tcctatctga ccttggtcac
     3961 ctttctaacg aggacggtgc tgaagctatg attcggacgc taggaaatcg tactaagaag
     4021 atttaccttg ggcatttatc taaggaaaac aatatcaagg aactggctca tatgaccatg
     4081 gtcaatcagc tggctcaagc tgatctggga gtcggagtag actttaaggt ttatgatacc
     4141 tcaccagata ccgcaacacc attgacagag atatagaaag aacgctgaga aggtgttctt
     4201 tttatattga ctgaacacct aaaaagtaat acaatggtgt taccattaaa aaagggagca
     4261 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
     4321 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
     4381 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
     4441 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
     4501 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
     4561 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagaccc
     4621 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
     4681 taattatcga gttatcgtac aaattgtaga tgatgaatta gtcgttgcta ctctagaagt
     4741 tggtcatcgg agagatattt attaaattaa agctgagtaa taacagtata gaaagtaagg
     4801 agagtaaaaa tttgaagaaa aaatggtttt ttgcagatta ttatgacaca acaattattt
     4861 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg attgatttgg
     4921 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
     4981 gttggcgctt ttttacgact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
     5041 tattggctat tctcccttta aatgctattt ttacagtgtt tcgattaggg cgtatctttc
     5101 gtttagctaa actaacaaaa ttactgaaac tgactcgttt acttagaata attggactta
     5161 caggtaaatt agaaagaaaa attagtagat tcttacggac aaatggcctg atttatatct
     5221 tgtatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
     5281 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggatatgggg
     5341 atattgttcc tgcttccatt tttgggaaat ggctagcagt tttactgatg cttgtcggta
     5401 ttggaacaat agggatgtta acaagtgctt tgacgaactt ttttgtaaag gataatccag
     5461 atgaacagat aaaacttgat aaactcaaag atgaattatc gagccaaaga atattactag
     5521 agaaacaatc taaaaagata gaagaactac ataaaatgat acaagatttg attgaaaaaa
     5581 cataataaaa ataaagatga gacaaagttt gagctgagga gaaatcaagt aagttttgac
     5641 acaatagaac gcatattatc aggtataaaa acttgatact atgcgtttta ttgtgggaag
     5701 atgtataatg gattgaaata agatatgaac aaatcgatta ggaatttaaa gcattttata
     5761 acaacgtttt agagtaacgg ggtactattt catataatac aggaaaaaac aactccctga
     5821 tgattcaagg agttgtctat agttaaatta gtttttagaa gcttcttgga attctggatt
     5881 tttccatgct tcgtcaataa tagcttgcaa ttctttagca gatgcttgca ttttttgagt
     5941 ttctgcatcg ttcaatggaa tgtttactgg acgaacgata ccatgtgcac caacaacagc
     6001 tggttgaccg ataaagacat tctcaactcc gtattgacct tcttggaata ctgaaagtgg
     6061 aagtactgcg ttttcatcgt caaggattgc tttagtgata cgagcaaggg ctactgcgat
     6121 accgtagtat gttgcacctt ttttgttgat gattgtgtag gctgcatcac gaacaccttc
     6181 gaacaattca atcaattcag cttcttgaac attttgagtg tctttaagga attcttcaag
     6241 gtttacacca gcgatgttag cgtgtgacca aacagcgaac tcagagtcac cgtgttcacc
     6301 catgatgtag gcgtgcactg aacgagcatc cacatccaat ttttcagcaa gtgcttgacg
     6361 gaaacgagct gagtcaagtg aagtacctga accgataacg cgttctttag ggaaaccaga
     6421 gaatttccaa gttgagtaag tcaaaacgtc aactgggtta gcagcaacaa ggaagatacc
     6481 tttgaaacca gattcaacaa cttgagttac gattgatttg ttgatagcaa ggtttttacc
     6541 tacaaggtca agacgagttt cacctggttt ttgaggtgca cctgcagtga tcacaacaag
     6601 gtcagcgtct gcacagtcag agtattgagc tgcatagatt tttttaggtg aagtgaaggc
     6661 aagggcgtga ctaaggtcaa gcgcatcacc aacagctttt tcatgcaatt gtggaatttc
     6721 gataattcca agctcttgtg caattccttg gttaacaagt gcaaaagcgt aagatgaacc
     6781 tacagcacca tcaccgacaa ggataacttt tttgtgttgt ttagttgaag tcattgtttt
     6841 aaacatctcc ttaattttat taggggattt tccctagaca acttcattct atcactttta
     6901 aaaaactttg tcacgaatat gccttatagt tctcgatgta aacgttttag tggtttagag
     6961 gctgaaatag atgggaattt atggtataat gttgttactt actaattgtg aaatgaggca
     7021 tttattaatg caggataaaa atttagtgaa tgtcaatctg acaaaggaga tgaaggcaag
     7081 ttttatcgac tacgccatga gtgttatcgt agcgcgagct cttcctgatg ttcgagatgg
     7141 cttaaaacct gttcaccgtc gcattctcta cggaatgaat gaattgggtg tgaccccaga
     7201 caaaccccat aaaaaatctg ctcgtattac aggggatgtc atgggtaaat atcacccaca
     7261 cggggattcc tctatttatg aagccatggt ccgtatggct caatggtgga gctaccgtta
     7321 catgcttgta gatggtcatg ggaattttgg ttctatggat ggagatagtg ctgccgctca
     7381 acgttatacc gaggcacgta tgagcaagat tgctctggaa atgcttcgtg atatcaacaa
     7441 aaatacagtt gatttcgttg ataactatga tgccaatgaa cgggaaccct tggtcttgcc
     7501 agcgcgtttt ccaaaccttt tggttaatgg agcaactggt atcgcggttg ggatggcaac
     7561 caatattcca cctcataatc tgggtgaaac cattgatgca gtgaagttgg tcatggataa
     7621 tcctgaagtg actaccaagg acttgatgga agtcttgcct ggaccagatt ttccaactgg
     7681 tgctcttgtc atggggaaat caggtatcca taaggcttat gaaacaggta aaggttcgat
     7741 tgtcctacgt tctcgtacag agattgaaac gactaagact ggtcgtgagc gtatcgttgt
     7801 aacagaattt ccttacatgg tcaataaaac caaggtgcat gagcatattg ttcgcttggt
     7861 tcaggaaaaa cgcattgagg gtatcacagc agtacgtgat gagtcaaacc gtgaaggtgt
     7921 tcgatttgtt attgaagtca agcgcgacgc ctcagccaat gttattctca ataacctctt
     7981 caaaatgacc caaatgcaaa ccaattttgg tttcaatatg ctcgctatcc aaaatggtat
     8041 accgaaaatt ttgtctcttc gtcagatttt ggatgcttat atcgagcacc aaaaagaagt
     8101 ggttgttcgt cgtacacgtt ttgataagga aaaagcggaa gcgcgcgctc atatcttaga
     8161 aggtctcttg attgcgctag accatatcga cgaagtgatt cgtatcatcc gtgctagtga
     8221 aacggatgcg gaggctcaag ctgagttgat gagcaagttt aagctttctg aacgtcaaag
     8281 tcaagctatc cttgatatgc gtcttcgtcg tttgacaggt ttggaacgcg ataagattca
     8341 atctgagtat gatgacctct tggctctgat tgcggattta gcagatattc ttgctaagcc
     8401 tgaacgtgtt tctcaaatta tcaaagacga attggatgaa gttaaacgta aattttctga
     8461 taaacgccgt acagagttga tggttggaca gatcttgagt ctcgaggatg aggacttgat
     8521 tgaagaatcg gatgtcttga ttaccctttc taacagaggc tacattaagc gtttggatca
     8581 ggacgagttc actgctcaaa aacgtggggg tcgtggtgtc caaggaacgg gagtgaaaga
     8641 tgatgacttt gttcgtgagt tagtgtcaac tagcacccat gatcatctgc tcttcttcac
     8701 aaacaaggga cgtgtctatc gtcttaaagg ttatgatatt cctgagtatg gtcggactgc
     8761 caaagggcta ccagtagtca atctcttgaa attggatgaa gacgaaagta ttcagacggt
     8821 tatcaatgtt gagtctgatc gcagtgatga tgcttatctc ttctttacaa cccgtcacgg
     8881 tattgtgaag agaaccagtg ttaaggagtt tgccaatatt cgtcaaaatg gtctcaaagc
     8941 gctgaattta aaggatgaag atgagttaat caatgtcttg ttggcagaag gagatatgga
     9001 tattatcatt ggtaccaagt ttggttatgc agttcgcttt aatcaatcag ccgttcgtgg
     9061 tatgagtcgt atcgccactg gtgtgaaagg tgttaacctt cgtgaaggag acacagttgt
     9121 tggtgccagc ttgattactg atcaagatga ggttcttatt atcacagaaa aaggatatgg
     9181 taagcgtaca gtcgctactg aatacccaac aaaaggtcgt ggtggtaagg gaatgcagac
     9241 agctaaaatt accgaaaaaa atggctttct ggccggtctt atgactgttc aaggggatga
     9301 ggatttgatg attatcactg atacaggtgt catgattcga accaatcttg ccaatatttc
     9361 acaaacagga cgtgcaacta tgggagttaa agtaatgcgc ctggatcaag atgctcagat
     9421 agtgactttc acaacggttg cggtggcaga aaaagaagaa gttgggacag aaaacgaaac
     9481 agaaggtgaa gcataatgtc tcaaaaaaat aataaaaaga aaaacaagcg aaaaaatctg
     9541 ctgacaaata tcctagcagg atttctgata ttactgtcac tggctttgat ttttaatact
     9601 caaattcgaa atattttcat agtctggaat accaataagt atcaagttag ccaggtctca
     9661 aaagaaaaat tagaagaaaa tcaggataca gaaggcaatt ttgactttga ttctgtcaaa
     9721 gctatctctt cggaagctgt tctaacttct caatgggatg ctcaaaaatt accagttatt
     9781 gggggaattg caattcctga attggaaatg aatttgccga tttttaaagg acttgataat
     9841 gttaatctct tctacggagc tggtacaatg aaacgtgagc aagtaatggg agaaggaaat
     9901 tatagtctag ctagtcacca tatctttggt gttgataatg ctaataaaat gttattttct
     9961 cctttagata atgctaaaaa tggcatgaag atttatctaa ccgataaaaa taaagtttat
    10021 acttatgaaa tacgtgaagt caaacgtgtg acaccggatc gtgttgatga agttgatgat
    10081 agagatgggg tcaatgaaat cacattagta acctgtgaag accttgctgc tacagaacgt
    10141 attattgtca aaggtgattt gaaagaaaca aaagattatt cacaaacatc tgatgaaatc
    10201 ctaacagctt tcaatcaacc atataaacaa ttttattaat acaaatcagt gaaatcatgg
    10261 atttcactga ttttttaaga ttttcataaa aatatagtaa aatgaa
//
LOCUS       DAVMAH010000068        10291 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVMAH010000068 DAVMAH010000000
VERSION     DAVMAH010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.068"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            635..1018
                     /locus_tag="VYO94_001836"
     CDS             635..1018
                     /locus_tag="VYO94_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1760421.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVFYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            1070..1759
                     /locus_tag="VYO94_001837"
     CDS             1070..1759
                     /locus_tag="VYO94_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1760422.1"
                     /translation="MKKYQLLFKTSAILSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1801..2034
                     /locus_tag="VYO94_001838"
     CDS             1801..2034
                     /locus_tag="VYO94_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760423.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            2185..2796
                     /locus_tag="VYO94_001839"
     CDS             2185..2796
                     /locus_tag="VYO94_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1760424.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            2957..3751
                     /locus_tag="VYO94_001840"
     CDS             2957..3751
                     /locus_tag="VYO94_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV1760425.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3748..4383
                     /gene="trmB"
                     /locus_tag="VYO94_001841"
     CDS             3748..4383
                     /gene="trmB"
                     /locus_tag="VYO94_001841"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV1760426.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4509..4988
                     /gene="rimP"
                     /locus_tag="VYO94_001842"
     CDS             4509..4988
                     /gene="rimP"
                     /locus_tag="VYO94_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV1760427.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            5032..6168
                     /gene="nusA"
                     /locus_tag="VYO94_001843"
     CDS             5032..6168
                     /gene="nusA"
                     /locus_tag="VYO94_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV1760428.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            6190..6483
                     /locus_tag="VYO94_001844"
     CDS             6190..6483
                     /locus_tag="VYO94_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV1760429.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6476..6775
                     /locus_tag="VYO94_001845"
     CDS             6476..6775
                     /locus_tag="VYO94_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV1760430.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6792..9584
                     /gene="infB"
                     /locus_tag="VYO94_001846"
     CDS             6792..9584
                     /gene="infB"
                     /locus_tag="VYO94_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV1760431.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9835..10185
                     /gene="rbfA"
                     /locus_tag="VYO94_001847"
     CDS             9835..10185
                     /gene="rbfA"
                     /locus_tag="VYO94_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV1760432.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3132 a         1881 c         2334 g         2944 t
ORIGIN      
        1 atgcttactt tttaaatttt ttaacaattc aagatgtttc gatgacaatt caagatttgg
       61 atgaaaaatt ttaaaaaaca atgatatact aaacttgtca aagttgcaac gggtgctgct
      121 acattatgtt aaaaatcgct cttgattgat aagctggatt tgttaggaaa ggagtaagta
      181 attatggata agaaaaagat agtttcgact ataatatgta tagtatttct tgtagtgtca
      241 gtagataatt tttttagaga cttaaccccg ttactgttca ttttcaatat tattggcctg
      301 tcttgctttt cagtgctaac atacattaac ataaaagaga tactcttaaa tataagtaaa
      361 tgatgatttg gttagtccta gaaccaatca acttatgttt atcggcttgg cagattttat
      421 gtttgtcatt tgtttgtata gaggtatttc agaaacagaa ttctatcaac aactaatcgc
      481 ttatataggt gtattctctg cttgtttatc acgcttctgc tcatgtgggg cttgaagtat
      541 tataaaaagt agctttctat ccttttctga caggatattt gagtagaagg ctctattaaa
      601 ttgttagtga aataaatgaa tggaggtatt taatatgaaa tacagattat tttttgttat
      661 tttcttgagt agtgtgttgg atattctttt agggacattt ttacaaatct ctatcgtatc
      721 tattgggtgg cttgtttttt acagtggttt gtttgaagca ggagttttcc ttcttgctaa
      781 taaaggggtg gcggtaaaaa tcaaggaagt agatattcga aatcgcttta aatttatttt
      841 tggaaaaacc ttatggtttc aaattctttt gctcatcttt ttgataatca aactttatct
      901 tggtttggat gcgaggttga ttttattcta tggacatatt ttcattgtct ttaatgcctt
      961 aatgtatcta ttatctagta gtcaggttag ccttaaaaaa aacaaactgt cttcttaatc
     1021 ttacagtagt agagcctgac aaggtgaggt catagtaggg aggatttcta tgaaaaagta
     1081 tcagcttcta ttcaaaacaa gtgcaatttt atcctaccta tttttcgtat ttggtctttc
     1141 tcagctgacg cttatcgtcc aaaactattg gcaattttct tctcagatag gcaatttatt
     1201 ctggattcaa aatatcttga gtttactttt tattggagtc atgattgtgg ttcttgttaa
     1261 gacaggccat ggttatctct tccgcattcc aagaaaaaaa tggctttggt attcgatttt
     1321 gacagtatta gtggtagtgt tccagatctc ttttaacgtt cagacagcta aacatgttca
     1381 gtcaactgcg gaaggttggg ctgtattgat tggttatagt gggactaact ttgcagagct
     1441 aggtatttat atagccctgt tctttctggt tccactgatg gaagaattga tttatagagg
     1501 attactgcaa catgctttct ttaagcattc gcgatttggt cttgatttgc ttcttccttc
     1561 tattttattt gctctccctc atttttcaag cctgcctagt ctgttagata tcttcgtctt
     1621 tgcaacagtt ggaatcatct ttgctggttt gacccgctat accaagagca tttatccatc
     1681 ctatgcggtg catgtgatca ataatattgt agcgaccttc ccgtttttgc tcacttttct
     1741 acatagggtc ttggggtaaa aaaacaaaag gcttgctttt cagccataga ggaggtcatc
     1801 atgtataaac acttattttt cctagattcc aaaactttag atcggttgac accctatatt
     1861 ctagtcttgg cttctgacac cattgctttt aatgtttttg tgctaacctt tgtatctgcg
     1921 gtggttttta atttcctaaa ttccatgcta gctttaatgg ctatattcat aggggctggc
     1981 tatgtggtcg gattttggtt actaatactc aatgaaaatc aaagagcaaa ctaggaaact
     2041 agccgcaggc tgtacttgag tacggcaagg cgacgttgac gtggtttgaa tttgattttc
     2101 gaagagtata aaatggtttg ttttggaaag gctagaacta aagaatgacg tgtaggaagt
     2161 ctgtttgttg aggaggataa ttttatggag ttttttgata aatttcatgc cttgtgtttt
     2221 ggatttttag tactaataat tgtcattaca gttccttata cgattaacca tgggggtttt
     2281 tttcaaaatg aatctgcatt gattcttgta agtcttcttg taacctcgct gagtgttgct
     2341 tatgctagaa agtttgaaat gatttctttt gggatgttaa gcaagaaaca acttttgctt
     2401 ttcattgcaa tctttcttct aagtgtactt gagacgctgg tttatattca tttcttcgct
     2461 gtttcttctg gctcaggggt ccaacacttg gcggaagtca gcagaggaat ttccctgtct
     2521 ttgattttaa ctacctcagt ttttggcccc atccaggagg aactcatttt cagaggactt
     2581 cttcaaggtg cggtttttga caattcttgg ttagggcttg tgctaacttc ctctctcttt
     2641 tctttcatgc atggaccttc taatgtccct tcgtttattt tttatctact tgggggtttg
     2701 ttgctgggct ttgcttataa aaagagtcaa aacctatggg tttctactct agtccatatg
     2761 ctttacaaca gttggccact cttatattat ttataaaaat tatgaaaagg taagcagaag
     2821 acggtgctta cctttttcaa gctataatga tacccaagcc aatccagagg cttttctttg
     2881 agaatcgggt tagagtggtt gacgaatagg ccaaaaacta gtagaatagt aaggaaactt
     2941 tatacggagg aaagaaatgg atttgggtga taatgagcta acactgactc ccatacctgg
     3001 gaaaagtggc aaggcttata tgggtagcta tcctgatggg aagcgcatct ttgtaaaaat
     3061 gaacacctct ccaatcctac ctggtctagc tagagaacaa attgctccac aattattatg
     3121 gagtcgtcgt ttggcagatg ggcgtgatat gtgtgctcaa gaatggttga caggcaagat
     3181 attgaccccc tatgatatga atcgtaagca aatcgtcaat attttaaccc gtcttcatcg
     3241 ctcacgtccg ttgatgacac aattgagtcg tttgggctat gccatggaaa cacctgtaga
     3301 tttactacag tcttggcagg aaacggctcc agatgctttg cgtaaaaatc attttatcag
     3361 tgaagtgatg gctgatttac gtcagactat tccaggattt agagaggacc atgcgaccat
     3421 tgtccatgga gatgtacgac atagtaattg gattgagaca gatagtggct tgatttattt
     3481 agtagattgg gattcggttc gcttgaccga tcgcatgttt gatgtggccc atatgctctg
     3541 ccattatatt tcagaacatc agtggaagga atggttgacc tactacggtt acaagtacaa
     3601 tcaaacggta ttaagtaaat tgtattggta tggtcaattg tcttatttga gtcagatttc
     3661 caagtattat atgaaccaag atttagaaaa tgtcaatcgg gagattcatg gtttgcgtca
     3721 tttccgagac aagtatggaa agagaagatg agagttagaa atcgtaaagg ggcaacagaa
     3781 ttactagagg caaatcccca gtatgtggtc ctcaatccct tggaagccaa ggcaaaatgg
     3841 cgggacttgt ttggcaatga taatcccatt catgtggaag ttggaagtgg aaagggtgcc
     3901 tttgtttcag gtatggccaa gcaaaaccct gacatcaact atatcgggat tgatattcaa
     3961 aagtctgttt tgagctacgc tttggacaag gtgcttgaag ttggagtgcc taacatcaag
     4021 ctcttgtggg tagatggttc tgacttaact gactactttg aagacggtga gattgatcgc
     4081 ttgtatctga acttttcaga tccatggccg aaaaaacgcc atgaaaagcg tcgtttgacc
     4141 tacaagacct tcttggatac cttcaaacgt atcttgcctg aaaatggaga aattcatttc
     4201 aagacggata accgtggctt gtttgagtac agtttagtga gcttttctca atatggcatg
     4261 aaactcaatg gtgtctggtt agatttgcat gccagtgatt ttgaaggcaa tgtcatgaca
     4321 gaatacgagc aaaaattctc aaacaagggg caagttatct accgagttga ggcagaattt
     4381 taagagataa cctaaaatta ggctgtacaa gtgcttttgc tttacataag ttggcaaacg
     4441 tgctatactg atagtaagaa tatgaaaagt gaggcgggga aatatcttcg cctcttgctt
     4501 atgaggaggt ggacgcaatc gcaacaatcg tagaattagt cagagaagtt gtagaacctg
     4561 tcatagaagc tccttttgaa ctcgtggata tcgagtatgg aaagattggc agtgacatga
     4621 ttctcagtat ttttgtagat aaacccgaag gaattacctt gaacgacacg gcagacttga
     4681 cagaaattat cagtcctgtc ctagacacca tcaagccaga tcccttccca gaacaatatt
     4741 tcctagaaat taccagtcca ggtttggaac gtcctttgaa aaccaaggat gccgtcgctg
     4801 gagcggttgg aaaatacatc catgtcgggc tctaccaagc catcgataag caaaaggtct
     4861 ttgaaggaac cttgttggcc ttcgaagagg acgagttgac tatggaatat atggacaaga
     4921 cgcgtaagaa aaccgtccaa attccataca gtttagtatc aaaagcacgt ttagcagtta
     4981 aattatagaa aaagaaagga tagcttttga ggattcaaaa gtgaagaaaa catgagtaaa
     5041 gaaatgctag aggccttccg cattttggaa gaagacaagg gaatcaaaaa agaagatatc
     5101 atcgacgcag tagtagagtc gcttcgttcc gcttatcgca gacgctatgg tcagtcagac
     5161 agcgtagcta ttgacttcaa cgaaaaaaca ggtgacttta cagtttatac tgtccgtgaa
     5221 gttgttgatg aagtatttga tagccgtttg gaaatcagct tgaaagatgc tcttgccatt
     5281 aattcagctt atgaacttgg agacaaaatc aagtttgaag aagcaccagc tgagtttggt
     5341 cgtgtagcag cccaatctgc caaacaaacc atcatggaaa aaatgcgcaa gcaaacacgt
     5401 gccatcactt acaatactta caaagaacat gagcaagaaa tcatgtctgg tacagtagaa
     5461 cgctttgaca accgctttat ctatgtcaac cttggtagca tcgaagccca attgtcaaaa
     5521 caagaccaaa ttcctggaga agtttttgct tctcatgatc gtatcgaagt ttatgtttac
     5581 aaggttgaag acaaccctcg tggtgtgaac gtctttgtta gccgtagtca tccagaaatg
     5641 atcaaacgtt taatggagca agaaattcca gaagtttatg atggaactgt tgaaatcatg
     5701 agcgtggctc gtgaagcagg tgaccgtacg aaggttgctg ttcgtagcca caatccaaac
     5761 gtggatgcta tcggtacaat cgttggacgt ggtggtgcta atatcaagaa gattactagc
     5821 aaattccacc cagctcgtta cgatgctaaa aatgaccgca tggtaccaat cgaagaaaat
     5881 atcgatgtta tcgagtgggt agcagatcca gctgaattta tctacaatgc catcgctcct
     5941 gctgaggttg accaagttat ctttgatgaa aacgacagca aacgtgcctt ggtggttgtt
     6001 ccagataaca agctttctct tgccattggt cgtcgtggac aaaacgtgcg cttggcggct
     6061 cacttgactg gttaccgtat cgatatcaag tctgctagcg aatttgaagc catggaagac
     6121 gctgcttcag tagagttgga agtagaaaac gatactgtag aagaataaaa gctgctagag
     6181 gagggaaaga tgaaaacaag aaaaatccct ttgcgcaagt ctgttgtgtc taacgaagtg
     6241 attgataagc gtgatttgct ccgcattgtc aagaacaagg aaggacaagt ctttattgat
     6301 cctacgggca aggccaatgg ccgcggcgct tatatcaaac tagacaatgc agaagcccta
     6361 gaggcgaaaa agaagaaggt ctttaaccgc agttttagca tggaagtgga agaaagcttt
     6421 tatgacgagt tgatcgctta tgtggatcac aaagtgaaaa gaagagagtt gggacttgaa
     6481 taagcaaaag ataagtaatc tcttggggct tgctcagcga gcagggcgca tcatatcggg
     6541 tgaagaattg gtggtcaagg ccattcaaga cggcaaggcc aagttggtct ttctagctca
     6601 tgatgctgga cccaatctga ccaagaagat tcaagataaa agtcattatt atcaagtaga
     6661 aattgtaacc gtgttttcaa cactggaatt aagcatagca gtcgggaaat cgagaaaggt
     6721 tttggctgta acagatgctg gatttacaaa gaaaatgagg tctcttatgg aatagaagag
     6781 gaggacatga tttgtctaag aaaagattgt acgaaatcgc aaaagaactt ggaaaagaaa
     6841 gtaaagaagt tgtagcgcgt gcaaaagagt tgggcttgga tgtgaaaagc cactcatcaa
     6901 gtgtggaaga agctgtcgct gcaaaaattg ctgccagctt taagcctgca gctgctccga
     6961 aagtagaagc aaaacctgca gcaccaaaag taagtgcaga aaagaaagcc gaaaaatctg
     7021 agccagctaa accagctgta gctaaggaag aggcaaaacc ggctgagcca gttgctccga
     7081 aaacagaaaa agtagcagcg aaaccgcaaa gccgtaattt caaggctgag cgtgaagccc
     7141 gtgctaaaga gcaggcagaa cgacgcaagc aaaataaggg caataaccgt gaccaacaac
     7201 aaaacggaaa ccgtcagaaa aacgacggcc gtaatggtgg aaaacaaggt caaagcaacc
     7261 gcgacaatcg tcgctttaat gaccaagcta agaagcagca aggtcagcaa aaacgtagaa
     7321 atgagcgccg tcagcaagag gacaaacgtt caaatcaagt ggctccacgt attgacttta
     7381 aagcccgtgc agcagcccta aaagcagagc aaaatgcaga gtacgctcgt tcaagtgagg
     7441 aacgcttcaa gcagtatcag gctgctaaag aagccttggc tcaagctaac aaacgcaagg
     7501 aaccagagga aatctttgaa gaagcggcta agttagctga acaagcacag caagttcaag
     7561 cagtggttga agtcgtccct gagaaaaaag aacctgcagt ggatacacgt cgtaaaaaac
     7621 aagctcgacc agacaaaaat cgtgacgatt atgatcatga agaagatggt cctagaaaac
     7681 aacaaaagaa tcgaagtagt caaaatcaag tgagaaatca aaagaatagt aactggaata
     7741 acaacaaaaa gaacaaaaaa ggcaataaca agaacaaccg taatcagact ccaaaacctg
     7801 ttacggagcg taaattccat gaattgccaa cagaatttga atatacagat ggtatgaccg
     7861 ttgcggaaat cgcaaaacgt atcaaacgtg aaccagctga aatcgttaag aaacttttca
     7921 tgatgggtgt catggccaca caaaaccaat ccttggatgg ggaaacaatt gaactcctca
     7981 tggtggatta cggtatcgaa gccaaacaaa aggttgaagt ggataatgct gacatcgaac
     8041 gtttctttgt cgaagatggt tatctcaatg aagatgaatt ggttgagcgt ccaccagttg
     8101 ttactatcat gggacacgtt gaccacggta aaacaaccct tttggatact cttcgtaact
     8161 cacgtgttgc gacaggtgaa gcaggtggta ttactcagca tatcggtgcc taccaaatcg
     8221 tggaaaatgg taagaagatt accttccttg atacaccagg acacgcggcc tttacatcaa
     8281 tgcgtgcgcg tggtgcttct gttaccgata ttacgatctt ggtcgtagcg gcagatgacg
     8341 gggttatgcc tcagactatt gaagccatca accactcaaa agcagctaac gttccaatca
     8401 tcgtagccat taacaagatt gataaaccag gtgctaaccc agaacgcgtt atcggtgaat
     8461 tggcagagca tggtgtgatg tcaaccgctt ggggtggaga ttctgaattt gttgaaatct
     8521 cagctaaatt caaccaaaat atcgaagaat tgttggaaac agtccttctt gtagctgaaa
     8581 tccaagaact caaggcagac ccaacagtgc gtgcaatcgg tacggttatc gaagcgcgct
     8641 tggataaagg aaaaggtgcg gtcgcaaccc ttcttgtaca acaaggtacc ttgaatgttc
     8701 aagacccaat cgttgtcgga aataccttcg gtcgtgtccg tgctatgacc aacgaccttg
     8761 gtcgtcgtgt taaagttgct ggaccatcaa caccagtctc tatcacaggt ttgaacgaag
     8821 caccgatggc gggtgaccac tttgccgttt acgaggatga aaaatctgcg cgtgcagcag
     8881 gtgaagagcg tgccaaacgt gccctcatga aacaacgtca agctacccaa cgtgttagcc
     8941 ttgaaaacct ctttgatacc cttaaagctg gggaactcaa atctgttaat gttatcatca
     9001 aggctgatgt acaaggttct gttgaagccc tttctgcctc acttcaaaag attgacgtgg
     9061 aaggtgtcaa agtgactatc gtccactcag cggtcggtgc tatcaacgaa tcagacgtga
     9121 cccttgccga agcttcaaat gcctttatcg ttggtttcaa cgtacgccct acaccacaag
     9181 ctcgtcaaca agcagaagct gacgatgtgg aaatccgtct tcacagcatt atctacaagg
     9241 ttatcgaaga gatggaagaa gctatgaaag ggatgcttga tccagaattt gaagaaaaag
     9301 ttattggtga agcagttatc cgtgaaacct tcaaggtgtc taaagtggga actatcggtg
     9361 gatttatggt tatcaacggt aaggttgccc gtgactctaa agtccgtgtt atccgtgatg
     9421 gtgtcgttat ctatgatggt gaactcgcaa gcttgaaaca ctataaagac gacgttaagg
     9481 aagttacaaa cggccgtgaa ggtggattga tgatcgacgg ctacaatgat attaagatgg
     9541 atgatgtgat tgaggcgtat gtcatggaag aaatcaagag ataagatttt ttgctccttt
     9601 cttaggtggt gagggacgca agcaaaccga tggtttcatt gcttattttt gagcctaggg
     9661 tctcaaaaat cccctgtgat gggactgata aatcagttcc atcactttca ccacggcgaa
     9721 agaagcatat gacttcaaat tgaacttcgt ttcaatttaa actgaaaatc aagaagttta
     9781 aaatagctag gtctgctggc ctagcttttg gttcaaagta gagaaaggaa tatcatggca
     9841 aatcatttcc gtacagatcg tgtgggcatg gaaatcaagc gtgaagtcaa tgagattttg
     9901 caaaagaaag tccgtgatcc acgtgtccaa ggtgtgacca tcacagatgt tcagatgctg
     9961 ggtgacttgt ctgttgccaa ggtttattac accattttga gtaaccttgc ttcggataac
    10021 caaaaagccc aaatcgggct tgaaaaagca actggtacca tcaaacgtga acttggtcgc
    10081 aatttgaaat tgtacaaaat cccagatttg accttcgtca aagacgagtc catcgagtat
    10141 ggaaacaaga ttgacgagat gctacgcaat ctggataaga actaaagaag aggggttgcc
    10201 cctctttttc ggctctttgt caactgtagt gggttgaagt cagctaagct cgagaaagga
    10261 caaatttcgt cctttctttt ttgatattca g
//
LOCUS       DAVMAH010000069         8542 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVMAH010000069 DAVMAH010000000
VERSION     DAVMAH010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8542
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.069"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(<1..137)
                     /locus_tag="VYO94_001848"
     CDS             complement(<1..137)
                     /locus_tag="VYO94_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760433.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKHGFEVVDETDEVS
                     S"
     gene            265..663
                     /locus_tag="VYO94_001849"
     CDS             265..663
                     /locus_tag="VYO94_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760434.1"
                     /translation="MENKESYKSQEIGNLIRAYNRSKREEAESEPLNLYVEDEKGNLL
                     EGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAL
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            1108..2115
                     /locus_tag="VYO94_001850"
     CDS             1108..2115
                     /locus_tag="VYO94_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1760435.1"
                     /translation="MQDNYTTKAKHLTIYSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGTKKMTSKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            2190..2390
                     /locus_tag="VYO94_001851"
     CDS             2190..2390
                     /locus_tag="VYO94_001851"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV1760436.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            2425..3141
                     /gene="atpB"
                     /locus_tag="VYO94_001852"
     CDS             2425..3141
                     /gene="atpB"
                     /locus_tag="VYO94_001852"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV1760437.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNILEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            3155..3649
                     /gene="atpF"
                     /locus_tag="VYO94_001853"
     CDS             3155..3649
                     /gene="atpF"
                     /locus_tag="VYO94_001853"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV1760438.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            3649..4185
                     /locus_tag="VYO94_001854"
     CDS             3649..4185
                     /locus_tag="VYO94_001854"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV1760439.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            4200..5705
                     /locus_tag="VYO94_001855"
     CDS             4200..5705
                     /locus_tag="VYO94_001855"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV1760440.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            5721..6599
                     /locus_tag="VYO94_001856"
     CDS             5721..6599
                     /locus_tag="VYO94_001856"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV1760441.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            6685..8091
                     /gene="atpD"
                     /locus_tag="VYO94_001857"
     CDS             6685..8091
                     /gene="atpD"
                     /locus_tag="VYO94_001857"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV1760442.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            8102..8521
                     /locus_tag="VYO94_001858"
     CDS             8102..8521
                     /locus_tag="VYO94_001858"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV1760443.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
BASE COUNT         2635 a         1575 c         1846 g         2486 t
ORIGIN      
        1 tttgagctga cttcgtcagt ttcatctaca acctcaaaac catgctttga gctgacttcg
       61 tcagttctat ctacaacctc aaaacagtgt tttgagcaac ctgcggctag tttcctagtt
      121 tgctctttga ttttcattga gtattagatg tatagtgcat tgaagttaaa atagtacact
      181 ttgatttcta agacattgtt agaaattaga ttaaattcct taatcgattt gcgcatgttt
      241 tatttcattt cattatactt tagattggaa aataaggaat catataaatc gcaagaaata
      301 gggaatctga ttcgtgctta taaccgttca aaaagagaag aggctgaaag tgagccactt
      361 aatctttatg tcgaagatga aaagggcaat ctccttgagg gtttgatagc agagactttt
      421 ggaaattggc tagaaatcga gtatttgttt gtaaaagagg aactgcgagg gcaaggaatc
      481 ggttcaaaac tattgcaaca ggcagaaagt gaagctaaga atcgaaattg ttgttttgcc
      541 tttgtcaata cttaccagtt ccaggcactg gacttttatc agaaacatgg ctacaaggaa
      601 gttttttctt tgcaagacta tctctacatt aggcaaagat attattacca aaagaatctg
      661 taaggtgagt atggaggtat aatacaaaga gaggctcgca cataagtatg gaggtggact
      721 gatgtatatg agtaactatc gataaatacc agttataacc tagaaattgt gtctttctag
      781 acgatattga ggacaatata atcgtagccc caaaattagg aatcaagact tatcaggtta
      841 agaaaagaag tgatgttgtt gatattttaa acaatttatt taaactaaaa actctctatc
      901 tattaatccg agattcccct ctcggatttt gtgttgcttt cattaaattt acaggtaaga
      961 cttgctagct tcagtaaata tacacaagtt tttcagaata gagtgaaatc caaaagaaaa
     1021 tggaaataat gaaagctctt gtaggcataa gaaaacacct ctgtgttata cttgttgttc
     1081 aaccacaaac acaagaaagg cacagagatg caagacaatt atactacaaa agccaaacat
     1141 ttgacaatct atagccgtcg cttaatcgaa agatggaaaa aagaagggaa atcaaataga
     1201 gaaattgcct ctctgcttgg aaaagttcct caaactatcc acactgaaat caagcgtggg
     1261 acagtccgac aatgtcttgg aaaagggcgc ttcaaagagg tttattctgc cgactatgct
     1321 caacagtctt atgaaaacaa tcgcaagcgc tcggtcaaga aatcaagctt gaccaaggaa
     1381 ctaaaggaaa agattctcca ctatcataac caaaaatttt cgcctgaaat gatggtgatg
     1441 gctaaagggg ttaacgtggg aatttcaacc atttactatt ggattcatca tggaaaattg
     1501 gggttaagca aacaggatct gctttaccct agaaaaggaa aagcgcttaa gaaacaggct
     1561 agcaccaact ttaaacctgc tggtcaatcc atcgaacagc ggtctgaagc tatcaatctt
     1621 cgcttggaga atgggcatta tgagattgat acggttctac ttacgagagc gaaaaactac
     1681 tgcttgcttg tcttgacgga tcgaaagagt agacatcaga tcatccgatt gattccaaat
     1741 aaaagtgctg aggtggtcaa tcaggctcta aaactcatct taaaacaaca caagattctt
     1801 tccatcacgg cagataatgg aacggaattc aatcgcttgt ttgatgtatt ttctgaggag
     1861 cacatctatt atgcgcaccc ctatgcctct tgggaaaggg gaactaatga gaatcacaac
     1921 aggctcattc gtagatggtt acctaaggga accaagaaaa tgacttccaa agaagtcgca
     1981 ttcatcgaaa agtggattaa caactatcct aaaaaatgct tggactacaa gtcacccaga
     2041 gaagacttct ggatggctaa cttgaacttg aaatttagca aaatggaaat aatttttatt
     2101 aaacgcttcc aatagcggtt aaaagttgac aaatttaaat tttaggacta cactaagtaa
     2161 gtaaatttta ttttaaagga gaatttgtta tgaatttaac atttttaggc ttatgtattg
     2221 cctgtatggg cgtatctgtc ggtgaaggtt tattgatgaa tggactgttt aaatcagtag
     2281 cacgccaacc agatatgctt tctgagtttc gtagtttgat gtttttaggt gttgccttta
     2341 ttgaaggaac tttctttgta actcttgtct tctcatttat tatcaaataa atacatggaa
     2401 cgagaagaaa agggaggatt ttagatggaa gaaagtatta atccaatcat ctctattggt
     2461 cctgttatct tcaatctgac tatgttagcc atgactttgt tgattgtggg agttattttt
     2521 gtctttattt attgggcaag ccgcaatatg accttgaaac ccaaaggaaa gcaaaatata
     2581 cttgagtatg tctatgactt tgttattgga tttacagaac ctaacattgg ttcgcgctac
     2641 atgaaagatt actcactctt tttcctttgt ttattccttt tcatggtgat tgccaataac
     2701 cttggcttaa tgacaaagct tcaaacgatc gatgggacta actggtggag ttcgccaacc
     2761 gctaatttac agtatgactt aaccttatct tttcttgtca ttttgttgac acatatagaa
     2821 agcgttcgtc gtcgtggatt taaaaaaagt ataaaatctt ttatgagtcc tgtttttgtc
     2881 ataccgatga atatcttgga agaatttaca aacttcttat ctttggcttt gcggattttt
     2941 gggaatatct ttgcaggaga ggtcatgacg agtttgttac ttcttctttc ccaccaagct
     3001 atttattggt atccagtagc ctttggagct aatttggctt ggactgcatt ttctgtcttt
     3061 atttcctgca tccaagctta tgtttttact cttttgacat ctgtgtattt agggaataag
     3121 attaatattg aagaggaata gaaaggagta actgatgcac gtaacagtag gtgaattaat
     3181 tggtaatttt attttaatca ctggctcttt tattcttttg ctagtcttga ttaaaaaatt
     3241 tgcatggtct aatattacag gcattttcga agaaagagct gaaaaaattg cttcagatat
     3301 tgacagagct gaagaagccc gtcaaaaagc agaagtattg gctcaaaaac gcgaagatga
     3361 attggctggt agccgtaaag aagctaagac aatcattgaa aatgcaaagg aaacagctga
     3421 gcaaagtaag gctaatatct tagcagatgc taaactagaa gcaggacact taaaagaaaa
     3481 agccaatcaa gaaattgctc aaaataaagt agaagcttta cagagtgtta agggtgaggt
     3541 cgcagatttg accatcagct tagctggtaa aatcatctca caaaaccttg acagtcatgc
     3601 ccataaagca ctcattgatc agtatatcga tcagctagga gaagcttaat ggacaagaaa
     3661 acagtaaagg taattgaaaa atacagcatg ccttttgtcc aattggtact tgaaaaagga
     3721 gaagaagacc gtatcttttc agacttgact caaatcaagc aagttgttga aaaaacaggt
     3781 ctgccttctt ttttaaaaca agtggcagta gacgagtcgg ataaggaaaa aacaattgct
     3841 tttttccaag attctgtgtc acctttatta caaaacttta tccaggttct ggcctacaat
     3901 cacagagcaa atctttttta tgatgtgctt gtagattgct tgaaccgact tgaaaaagaa
     3961 acaaatcgat ttgaagtgac gattacgtct gctcatcctc taactgatga acagaagact
     4021 cgtttgctcc ctttgattga gaaaaaaatg tctctgaaag taaggagtgt aaaagaacaa
     4081 atcgatgaaa gtctcattgg tggttttgtc atttttgcca atcacaagac aattgatgtg
     4141 agtattaaac aacaacttaa agttgttaaa gaaaatttga aatagaaagt ggtgttcttt
     4201 tggcaattaa cgcacaagaa atcagcgctt taattaagca acaaattgaa aatttcaaac
     4261 ccaattttga tgtgactgaa acaggtgttg taacctatat cggggacggt atcgcgcgtg
     4321 ctcacggcct tgaaaatgtc atgagtggag agttgttgaa ttttgaaaac ggctcttatg
     4381 gtatggctca aaacttggag tcaacagacg ttggtattat catcctaggt gactttacag
     4441 atatccgtga aggcgataca atccgccgta cagggaaaat catggaagtc cctgtaggtg
     4501 aaagtctgat tggtcgtgtt gtggatccgc ttggtcgtcc agttgacggt cttggagaaa
     4561 tccacactga taaaactcgt ccagtagaag caccagctcc tggtgttatg caacgtaagt
     4621 ctgtttcaga accattgcaa actggtttga aagctattga cgcccttgta ccgattggtc
     4681 gtggtcaacg tgagttgatt atcggtgacc gtcagacagg gaaaacaacc attgcgattg
     4741 atacaatctt gaaccaaaaa gatcaagata tgatctgtat ctacgtcgcg attggacaaa
     4801 aagaatcaac agttcgtacg caagtagaaa cacttcgtca gtacggtgcc ttggactaca
     4861 caatcgttgt gacagcctct gcttcacaac catctccatt gctcttccta gctccttatg
     4921 ctggggttgc tatggcggaa gaatttatgt atcaaggtaa gcatgttttg attgtatacg
     4981 atgatctatc aaaacaagcg gtagcttatc gtgaactgtc gctcttgctt cgtcgtcctc
     5041 caggtcgtga agccttccca ggggatgttt tctatctcca cagccgtttg cttgagcgct
     5101 cagctaaagt ttctgatgaa cttggtggtg gatcaattac agccctacca tttatcgaga
     5161 cacaagcagg agatatctca gcctatatcg caaccaacgt gatttctatc actgatggac
     5221 aaatcttcct tggcgatggc ctcttcaatg caggtattcg tccagccatc gatgcgggtt
     5281 catctgtatc tcgtgtaggt ggttctgcac aaatcaaagc catgaagaag gttgctggta
     5341 cacttcgtat cgaccttgct tcataccgtg agttggaagc ctttactaag tttggttctg
     5401 acttggacgc agcaacacag gctaagttga accgtggacg tcgtaccgtt gaggtcttga
     5461 aacaacctgt tcacaaacca ttacctgttg agaaacaagt aaccattctt tatgctttga
     5521 cacatggttt cttggatact gttccagtag atgatattgt tcgtttcgag gaagagttcc
     5581 atgccttctt tgatgctcaa catccagaga ttttggaaac cattcgtgat acaaaagact
     5641 tgccagaaga agcagtcttg gatgctgcga ttacagagtt tctcaatcaa tctagcttcc
     5701 aataagaata gaggtgtcag atggcagtgt ctctaaatga tattaaaaca aaaatcgcct
     5761 caacaaaaaa tacgagtcaa atcactaatg ccatgcaaat ggtatcggct gctaagttag
     5821 gtcgctctga agaagctgct cgcaacttcc aagtttacgc tcagaaagtg cgtaaacttt
     5881 tgacagatat ccttcatggt aatggagctg gtgcttcaac taatccgatg ttgattagcc
     5941 gttctgtgaa gaagacaggc tatatcgtta tcacttcaga ccgcggtttg gttggaggtt
     6001 ataattcctc tattttgaaa gctgttatgg agttgaaaga agaataccac ccagacggta
     6061 aaggttttga aatgatctgt atcggtggga tgggagctga tttctttaag gctcgcggta
     6121 ttcaaccact ttatgaatta cgtggcttgg cagaccaacc tagctttgat caagttcgta
     6181 agattatttc aaaaactgtt gaaatgtacc aaaatgaact ctttgatgag ctttatgttt
     6241 gctacaacca ccatgtcaat acgctaacca gtcaaatgcg tgtggaacaa atgcttccga
     6301 ttgttgactt ggatccaaat gaagcggatg aagagtacag cttgactttt gaattggaaa
     6361 ccagccgaga agaaattctg gagcagttgt tgcctcagtt tgcagaaagt atgatttacg
     6421 gtgctattat cgatgccaag acagctgaga atgctgcggg tatgacagcc atgcaaacag
     6481 cgacagataa tgctaagaaa gtcatcaatg atttgacaat tcagtataac cgtgccagac
     6541 aggcggcgat tacacaagaa attacagaaa tcgtagcagg tgctagtgcc ttagaatagg
     6601 ctctagtcca gctcgtatga aaatgaactt aggacctagt tgagctagga accgacagta
     6661 tcttatatag aataggagaa ggagatgagt tcaggtaaaa ttgctcaggt tatcggtccc
     6721 gttgtagacg ttttgtttgc agcaggggaa aaacttcctg agattaacaa tgcacttgtc
     6781 gtctacaaaa atgacgaaag aaaaacaaaa atcgtccttg aagtagcctt agagttagga
     6841 gatggtatgg ttcgtactat cgccatggaa tcaacagatg ggttgactcg tggaatggaa
     6901 gtattggaca caggtcgtcc aatctctgta ccagtaggta aagaaacttt gggacgtgtc
     6961 ttcaacgttt tgggagatac cattgatttg gaagctcctt ttacagaaga cgcagagcgt
     7021 cagccaattc ataaaaaagc tccaactttt gatgagttgt ctacctcttc tgaaatcctt
     7081 gaaacaggga tcaaggttat tgaccttctt gccccttacc ttaaaggtgg taaagttgga
     7141 cttttcggtg gtgccggagt tggtaaaacc gtcttaatcc aagaattgat tcacaacatt
     7201 gcccaagagc acggtggtat ttcagtattt actggtgttg gggaacgtac tcgtgagggg
     7261 aatgaccttt actgggaaat gaaagaatca ggcgttatcg agaaaacagc catggtcttt
     7321 ggtcagatga atgagccacc aggagcacgt atgcgtgttg cccttactgg tttgacaatc
     7381 gctgaatact tccgtgatgt ggaaggccaa gacgtgcttc tctttatcga taatatcttc
     7441 cgtttcactc aggctggttc agaagtatct gcccttttgg gtcgtatgcc atcagccgtt
     7501 ggttaccaac caacacttgc tacggaaatg ggtcaattgc aagaacgtat cacatcaact
     7561 aagaagggtt ctgtaacctc tatccaggct atctatgtgc cagcggatga ctatactgat
     7621 ccagcgccag caacagcctt cgctcacttg gattcaacaa caaacttgga acgtaagttg
     7681 gtacaattgg gtatctaccc agccgttgac ccacttgctt caagctcacg tgccttggca
     7741 cctgaaatcg ttggagaaga gcactatgca gttgctgctg aagtaaaacg tgtccttcaa
     7801 cgttaccatg aattgcaaga tatcattgct atccttggta tggatgagct ttctgatgaa
     7861 gaaaagacct tggttgctcg cgcccgtcgt atccagttct tcttgtcaca aaacttcaac
     7921 gttgcggaac aatttactgg tcagccaggt tcttatgttc cagttgctga aactgtacgt
     7981 ggctttaagg aaatccttga tggtaaatac gaccacttgc cagaagatgc cttccgtggt
     8041 gtaggttcta tcgaagatgt gattgcaaaa gctgaaaaaa tgggatttta agaggtgacc
     8101 tatggctcag ttaactgtcc agatcgtgac accagatggt ctcgtctatg atcaccatgc
     8161 cagctatgta tcggttcgaa ctctggatgg tgagatgggg atcttgccac gacatgaaaa
     8221 tatgattgcg gttttagcag ttgatgaagt aaaggtaaaa cgtatcgatg ataaagatca
     8281 cgtgaactgg attgcagtaa acggtggcgt tattgaaatt gccaatgata tgatcacaat
     8341 cgtcgctgac tctgcagaac gtgctcgtga tatcgatatc agtcgtgcag aacgtgccaa
     8401 acttcgtgca gaacgtgcaa ttgaagaagc acaagacaaa catttgattg accaagaacg
     8461 tcgtgctaag attgctttgc aacgtgccat taaccgtatt aatgtcggaa atagactata
     8521 agaaaaaatg aacttgaaaa ta
//
LOCUS       DAVMAH010000070         8467 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVMAH010000070 DAVMAH010000000
VERSION     DAVMAH010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8467
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.070"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            61..1741
                     /locus_tag="VYO94_001859"
                     /pseudo
     CDS             61..1741
                     /locus_tag="VYO94_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            2009..2575
                     /locus_tag="VYO94_001860"
     CDS             2009..2575
                     /locus_tag="VYO94_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760444.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            2896..3084
                     /locus_tag="VYO94_001861"
     CDS             2896..3084
                     /locus_tag="VYO94_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1760445.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            3146..3904
                     /locus_tag="VYO94_001862"
     CDS             3146..3904
                     /locus_tag="VYO94_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1760446.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            3962..4816
                     /locus_tag="VYO94_001863"
                     /pseudo
     CDS             3962..4816
                     /locus_tag="VYO94_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
     gene            4928..5812
                     /locus_tag="VYO94_001864"
     CDS             4928..5812
                     /locus_tag="VYO94_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1760447.1"
                     /translation="MKKVMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            5975..7714
                     /locus_tag="VYO94_001865"
                     /pseudo
     CDS             5975..7714
                     /locus_tag="VYO94_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            7989..8444
                     /locus_tag="VYO94_001866"
     CDS             7989..8444
                     /locus_tag="VYO94_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760448.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNIIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
BASE COUNT         2956 a         1185 c         1801 g         2525 t
ORIGIN      
        1 tccaaagtta aattaaaaaa attatatatg atatagaaaa attatattga ggttaatact
       61 atgtcaaaag aaaaaataaa agtatacctc tatacacgag tatctacgtc aatacagata
      121 gaggggtatt cgttagaggc acaaaaatca cgaatgaaag cttttgctat ttacaacgat
      181 tatgaaattg ttggagagta tgaagatgcc gggaagtctg gcaagtctat tgaaggtaga
      241 atacagttca atcgaatgat ggaagatata aaatctggaa aagatggagt atcttttgtt
      301 cttgtgttta agttatcaag atttgcaaga aatgccgctg atgttctttc tacacttcag
      361 ataatgcagg attatggagt taatcttatc tgcgttgaag atggcattga ttcatctaaa
      421 gatgctggga aactaatgat ttctgtttta tcagctgtgg ctgaaataga aagagaaaac
      481 atccgtattc aaacaatgga aggtcgcatt caaaaagcaa gggaaggaaa atggaatggt
      541 ggctttggct ccgtatggat ataaacttga agacggcaag ctgtttataa atgaagaaga
      601 ggcagttgca ataagaacga ttttcgacca gtatgtaaat actacgatag gagccaatgg
      661 gatatctaaa tacttagaga atcatggaat tagaaaaatc ccaagacaga atggtaagaa
      721 tcctttgttt gatgcaggtc ttataagaaa gatattaaag aatcctgtat ataatgggaa
      781 aatagcattt ggaagaagaa ctttagaaaa agttcatggt acaagaaatg aatataagca
      841 ggttgaacaa gatgaatatc taatatctga agggatacat gaagctatag tttccgatga
      901 agtttggcaa gctgctcagg ttaagctaaa atctcaagca aagaaatatg agcatgtgaa
      961 taaaggaaaa gatacacgca cacacttgct ttctggaatt gtaaaatgcc cgatatgtgg
     1021 agtgggaatg tttgggaaca agtgtatcaa gaaaaagaaa gatggcacaa agtataaaga
     1081 tttttattac tatggttgta aacataggca gatgataaga ggtcataagt gtacattcag
     1141 taagcaaatt agagaagaat tgttagatga tgctgttgca gaggtgattg tcaagatagt
     1201 aagtaatccg aaatttgctt ctatgatgca agaaaaaatc aacatgaagg tggatacctc
     1261 tgaaatagaa aaagaaatag ataattacca aaaggaattg agaaagagtc attctacaaa
     1321 gtttaagcta attgaggaaa tagataattt agatgttgaa gataagcact ataagagaag
     1381 gaaacaggat ttagatgata gactatatcg tatgtatgac aaaatagatg aattagaatc
     1441 atcactaatt gatgcgaaag caaagaaaca gactattgaa gctgaaaaac ttacaggaga
     1501 taacatatat aaggttctga tctattttga taagctctat aaagtcatga atgatgtaga
     1561 gcgtaggcag ttaatttcag ctttgatttc tgaaattcaa gtttatgaag aaaaacaatc
     1621 taacggacaa tggctaaaat ccattacttt taagctacca attatagaag aaaatctcaa
     1681 catagatttg gacaatgatg aacaagttga atgtgtaagt ttattagaga aacgtagtta
     1741 atcctcaaaa ggttccccaa actttttgag tcccactgac gcatcacgct gaggcggtat
     1801 cactgcttgt acgagttgaa gcatcagcga agtaaaagta gatgttcagc caatgcgacg
     1861 aggtgagacc gaaggtcgat aaggtgtgtt ctgggtatag gactcgtaaa gtaagtagga
     1921 aatatgatga gatgatacag agagcctgaa ttggtcaggt gacgtgctta tttacattag
     1981 cctgataatg aaaatggaga gattatcgat ggttatattg gaattgtacc aaaatgatta
     2041 ttctaaagat ttagtagcat ttgattccat agaagatggg aaagcctttg tagctcaaat
     2101 cccgggatac actctggaaa cagaagatgg ttttgaagtg gagtatttta atcctaaaaa
     2161 cataccggat tatatggaaa ttatttttaa cggaaatatt gttcctttat ctaaatttat
     2221 gttcgatcct gaggaaaatg taaacattat ttggaaagag atttcaaatt tatccctcaa
     2281 aaatgataga gtgatcgaag gatattcaaa aattgatgca tatgtcgtta acaaccatga
     2341 agttaaagcc tatgtcgaaa caagagaaac gaactatcgt aaagcaaaag acttcttaga
     2401 aagccgcgga tatgaaatcg acagaagctt tttcggaagt gaagacggtg aagcgattct
     2461 ttacagaaaa aaagggatcg aagtttggca tttcttgtgt cacttagacc caatgtttgt
     2521 agagattgaa gatgtagaag gatatgttaa agaagaagtt ggagagattc aatagtcaac
     2581 caaagttcct tgtgagtata tacctttgct agtaaaagag tcaaaacgtt ataacgaagg
     2641 gggggagaaa atccttgagt gtaagtcttt ttcttgttta gagggaaagt attagagtag
     2701 ccgctcataa tttatactag atttgataac tgatttgaga cagattttat ttctataaat
     2761 attgtgaaaa ttttttaata ccaaagattt aaagttactg tgttaaaaat cctctccact
     2821 tttaaactaa tgtattataa aagccagttg acacaagtgt tacacctgtg atagaattaa
     2881 cttgaggtga tgaaaatggc aaccgataaa aatagaataa tgattagctt ggatgataaa
     2941 aatctagaga aacttgaaaa tttagtagaa gatgctagag atagaagggg aatgcgacta
     3001 acaaagtccc aggttattga attactccta aataccgttg attatttcga tgatattatg
     3061 ggagctattt actcaaaaaa ataagagcaa aattgctatt attttttaca aatcggtgta
     3121 acactagtga tataggagtg atgaaatggt tgtttatatt agacaaagta aattaccaag
     3181 tgaggtttca attaataaat acaatgctca agtaggtgcc tacttacaag gagaagaagt
     3241 tattttatat caatcttttt ctgaaataaa agagttaaca agtgaagata tagttgtaga
     3301 ttatataatg gagactagag cattactaaa aatgatgggc ttaaacgttc cggtttatga
     3361 ctatcctatt gagcttaaag agttttatgg tcgaaagatt tatgctggta ttttaggaga
     3421 gattgtgaat atacctgata attggggaaa atttattaag cctaaagctg gttcaaaagt
     3481 ctttactgga agagttgtta atggaaccca tgatttaata ggtattggtc tacctttcga
     3541 ctatcctata tggattagtg aggttgtaga attcatagct gaatggcgtt gttttgtgtt
     3601 agatggtcgc gtattagatg ttcgacccta tacaggtgat tatcatgcac aatttgatgc
     3661 aagtgtaatt gatgaagcga tatcatgttg gaaagatgcg ccaatagctt atggactaga
     3721 tatcggtgtt actcgcgatg gcagaacact tgttgttgaa gtaaatgatg gttatgcatt
     3781 gggaaattat ggcctatctc ctttaaaatc aatcaatttt catagagcta ggtggaaaga
     3841 aatggtaaaa ccctattttg aaaaaaatga aatttttaaa atccaacagg atgttatttt
     3901 ctaaaataaa tatggtagat aaccaatata aaaagcatca aaatgaacaa ggaggaatct
     3961 gatgcttgga gtaattattg gagatattgt cggttctgtt tacgaatgga acaatatcaa
     4021 aacaaaggac tttcctttat ttcggaagga ctgctttttt acagatgaca cggttatgac
     4081 ctgtgctgtt gcagaagcaa ttatgaatgg tggacaaaaa gacgatttca ttgacgcgat
     4141 gaagaaatat ggcagaatgt atccgaatgc tgattacggt gctcggttta atgcatggct
     4201 aaacagcgat aaccgtgagc cttataatag ctttgggaat ggatcagcta tgcgtatttc
     4261 tccatgtgct tggatcatgg actgtggttt ttatgcgaaa actggtatat ggccatcatc
     4321 tagaggactt acgagtcttt ctgcagaggt aactcataat catccagaag gtgtcaaagg
     4381 cgctatggct acagttgatg ctatctttct atgtcgtttt tactttggtg gttattgtag
     4441 agagtacgag caatcaatta acgacaatct tacagagtgt aaaagacgaa ttaaggatta
     4501 tatagaaaaa gaatacgatt acaatctatc tcaaacttta gatgaaatcc gtcctaacta
     4561 tcgttttaac gaaacatgtc aggaaactgt ccctcaagcc attatcgcct ttcttgaaag
     4621 tagagacttc gaagatgcga taagaaatgc catctcactt ggtggcgaca gtgatactct
     4681 cgcagcaatc acttgtagca tagcagaggc agcttacggt attcctgatt gaatcaagga
     4741 taaggcctat tcttacttgg atgaaccctt aaaggatgta gttaggcgat gggaaaatag
     4801 aataaaagcg tattaatctc cagtacgtca gatttctctt ttctgtattt tcattgtata
     4861 ataggattac atttacttgc atacgacgaa atgtaaacat ttctgtttaa aattaaggat
     4921 aaaatcaatg aaaaaagtaa tggtaattat caaccctact tctggtggcg agaaggcttt
     4981 ggattacaaa gaaaagctgg agaataaagc aaaagaatac tttgaatatg ttgaaaccaa
     5041 aattaccgaa aaagcgctgg atgcaacaca ttttgctgaa gaagcttctc gtgagcagta
     5101 tgatgcagtg gttgtgtttg gtggagatgg aactgtcaat gaagtcattt caggtattga
     5161 tgagagagac tacattccta agttagggat tatcccaggc ggtacgggta acctcattac
     5221 aaaacttttg gaaatcaatc aagacatcga tggcgcaatt gacgaactgg attttgattt
     5281 aaccaataag attgatatcg gtaaagcaaa tgacaactat tttggttata tctttagtat
     5341 cggttctctg cctgaggcga ttcacaatgt tgaaatagag gacaaaacaa aattcggtat
     5401 tttaacctat gctgtaaata ccatgaagtc tgtcatgaca gatcaggtct ttaacattaa
     5461 ggttgagaca gaaaatggaa attatgttgg tgaagctagc catgttttgg tccttttgac
     5521 aaattacttc gctgataaga aaatctttga agaaaacaag gacggctatg ccaacatttt
     5581 gattctgaaa gatgcctcta tattctccaa attatccgtc attcctgatt tattaaaagg
     5641 ggatgttgtc gcaaatgata atatcgagta tatcaaagcg cgtaatatta aaatctcttc
     5701 agatagtgaa ttggagtcag atgttgacgg agataaatca gataacctac ctgtagaaat
     5761 caaagtccta gctcagcgag tagaagtatt ttcaaaaccg aaagaggatt agtatataga
     5821 gaaagccttt tttaaggctt tttgtatact ttaaaagata gttcctttaa caacggacat
     5881 tccttgcaaa tagtttacaa aaatagtata ctggatttat tgagtttgaa aacgtttgcg
     5941 taaaatttga atgaatactt taggagacaa attgatggaa ttgagtgcta tttaccatag
     6001 gcctgagtcg gagtatgcct atctttataa ggataagaaa ctccatattc gaattcgaac
     6061 taagaaaggg gacattgaaa gcatcaactt gcactatggg gacccttttg tctttatgga
     6121 ggagttttat caggatacaa aagaaatggt caagataact tctggtacct tatttgacca
     6181 ttggcaggtt gaagtgtcag ttgactttgc acgtatccag tatctctttg agctcagaga
     6241 tacagaaggt caaaatattt tgtatggcga taaagggtgt gtggaaaatt ctctagaaaa
     6301 tcttcatgca attgggaatg gatttaagtt gccttatctt catgagattg atgcctgcaa
     6361 ggttcctgac tgggtttcaa atacggtatg gtatcagata tttcctgaaa gatttgccaa
     6421 tggcaatgct ctattaaacc cagaagggac tttagactgg gattcatctg tcacacctaa
     6481 gagcgatgat ttctttggtg gtgatttaca ggggattatt gatcatatgg attacttgca
     6541 agacttgggt attactggac tatatctttg tcccatcttt gaatctacaa gcaatcacaa
     6601 gtacaatacg acagattact ttgaaattga ccgtcatttt ggagacaagg agacctttcg
     6661 ggaactggtg gatcaagcgc atcatcgtgg catgaaagtc atgctggatg cggtatttaa
     6721 tcatattggt tcgcaatctc ttcaatggaa aaatgtcgtc aaaaatggtg aacagtctgc
     6781 ttataaggat tggttccata ttcaacaatt cccagtgaca actgaaaagc tagttaataa
     6841 gagagactta ccctatcatg tttttggttt cgaggactat atgcctaagc taaatacagc
     6901 caatccagag gtcaagaatt atcttttaaa ggttgcgact tattggattg aagagtttaa
     6961 tatcgatgct tggcgtttgg atgtggctaa tgagattgac catcagttct ggaaggattt
     7021 tcgtaaggca gttttagcta aaaatcctga tctttatatc ctaggagaag tctggcatac
     7081 atctcagcct tggctaaatg gagatgagtt ccatgccgtc atgaattatc ctttatctaa
     7141 tagtatcaag gactatttct tacgaggaat taagaagaca gaccagttca tcgatgaaat
     7201 caattgagag tctatgtatt acaagcagca gatttcagag gtcatgttta atctcttgga
     7261 ttcacatgat acagagcgaa tcctgtggac ggccaatgaa gatgttcaac tggttaaatc
     7321 agccttagcc tttctctttt tacaaaaagg aacaccgtgc atttattacg gaaccgagct
     7381 agccttgact ggaggaccag atccagattg tcgtcgttgt atgccttggg aacgtgtatc
     7441 aagtgacaat gatatgctga actttatgaa gaggctgatt aagattcgga aatacgcgtc
     7501 agtaatcatt tcgcatggca agtatagcct tcaagaaatc aaatctgatc tagtagctct
     7561 ggaatggaaa tacgaaggac ggatcctcaa agcaatattc aaccaatcaa cagaagatta
     7621 tcttttagag aaagaagcag tagcactagc aagcaattgc caagaattgg agaatcagct
     7681 tgtcatctct ccagatggat ttgtgatttt ctaaaaacta gttgatgaag attatggtac
     7741 atttcatatc ttatatagta taataaggct agttactaaa cttgtaaagg agaacttaaa
     7801 tgaattgtag aggacatgaa acaagacaaa gaattgttag agattttgaa gtttagccta
     7861 aagcacatat taagctgtta gcaaatcaac aaaaacatag tgatgtagga gcaactattg
     7921 aagatgaata ttatgtattt atcgctgaga gtaaaattga tggcaagaag gaagttattc
     7981 agtgttgcat gggtgcggca agggattttt tagaactaat taatcacaaa gggctacctc
     8041 tttttaatcc gcttgtaggt gattctcatg taaataatag acaagaatat gacaatacag
     8101 ggagtggaaa tttacaacct gaaaagtgga atgaaactgc aaagcagctt tataatatta
     8161 taatgtggtt gattatttta tggaatgcta agccggatac acctttattt aattttaaag
     8221 acgaagtaat taagtataaa acatatgagc cttttgaaag cagtataaaa agagtaaata
     8281 ctactataaa gaatggtagt aaagggaaaa ctctgactga gatgattaat ggctacagag
     8341 cggataacga tattagagat gaaatttgta actttaatat tctgaaaaat aaaattcgtg
     8401 atatgaaaga ccaacaagga aatacaatgg aatcttactt ttagttattg ttgaattttg
     8461 ggtattc
//
LOCUS       DAVMAH010000071         8290 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVMAH010000071 DAVMAH010000000
VERSION     DAVMAH010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8290
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.071"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            149..796
                     /locus_tag="VYO94_001867"
     CDS             149..796
                     /locus_tag="VYO94_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV1760449.1"
                     /translation="MVVGIAIASGYLNSHLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            927..1340
                     /locus_tag="VYO94_001868"
     CDS             927..1340
                     /locus_tag="VYO94_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760450.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            1359..1773
                     /locus_tag="VYO94_001869"
                     /pseudo
     CDS             1359..1773
                     /locus_tag="VYO94_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1812..2255)
                     /locus_tag="VYO94_001870"
     CDS             complement(1812..2255)
                     /locus_tag="VYO94_001870"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV1760451.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(2285..4507)
                     /locus_tag="VYO94_001871"
     CDS             complement(2285..4507)
                     /locus_tag="VYO94_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV1760452.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREVLV
                     DEVVTKLEEYTTERHLKGNIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            5523..6152
                     /locus_tag="VYO94_001872"
     CDS             5523..6152
                     /locus_tag="VYO94_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1760453.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(6275..8167)
                     /gene="pepO"
                     /locus_tag="VYO94_001873"
     CDS             complement(6275..8167)
                     /gene="pepO"
                     /locus_tag="VYO94_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV1760454.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         2254 a         1904 c         1587 g         2545 t
ORIGIN      
        1 cctttatttt cagggtttta tttctatcat tttattttac tttcatttgg tgggagaata
       61 tttgaaaaaa agaaaggtag tttaacctat gaaaaaatca ctaaaaattt ttgctacatc
      121 taaatagttt gacctcttcg gggttgcttt ggtcgttggg attgcgattg catctggtta
      181 cctcaactca cacctcgata aatttgtaga ctggggatca tggacagctc ttgtaccctt
      241 tggattgatt tccgtaacca acgttgggat ttccatgttg tccactcgtt tcacggggaa
      301 attaagcaaa tggggaaatt actttggtat tgttaatacc attttgtccg gtgctattga
      361 ttatatcctt ggaaataagg cggccatcat tacctatccc gtcaccttcc tcatttatac
      421 ctttgctata aagaagtggg aagcttcgca agaaggcaga cccaaccaaa tgagccaaaa
      481 acaggtaaaa ttggcggcca tcatcatttc catcatcgcc ttcctctttg cctttgtgac
      541 caactatatc ggatatgggg gcaagatgaa tctccttgcc tacgtaacaa ctattgcctt
      601 tgcactgtcc ctcattgcca atgctttgaa tgcattaaaa ctaacaactc agtggggctt
      661 ttggttgatt tacaatttcg ttcagctgac aaaagctggt attcaaggaa acttcgccaa
      721 tatcggtaaa tacatctttt atatcctcaa tgcaatcgga gctttatttg tctggaatga
      781 tgaagaagtt agataataga aggaaactca aataaagaat actagccaac ttaagagaat
      841 ctcccttctg ctatttttat cattttagtt gtaactccca ttcttttgga gtagaatgaa
      901 gttagataaa agaggaaggt cttgtcatga aaaaactcta tagaatccat tttatagcaa
      961 ttgcagttat tgatttgcta ctatttgcat tttttatcac tagactcgag acatcttttg
     1021 agtggctctt gctctctggt ttaattttct tccttgctca aggactcctg ctatttctct
     1081 tggtcgtccg actcaaacat caattcgctg agatttatcc tcaaatcaat aaaaagattc
     1141 gcttctacta tttaggggtt ctcaccattg attttctatt ttttgttctc ttagccttca
     1201 ttagttctca gcgtttttca tctcttatgc caatcatcac tgcttgccat tctacttttt
     1261 attatatgac agctgactac ctaagagaaa actatccaga cttttacgac aaacacatct
     1321 ctttatggga gtgtctctaa ggaaaaggag gttttagcat gaaaaaaatc atcttcatca
     1381 aaaccattca actccttgtc attgatggaa tcatgctggc atttttgaca tttaaaaggg
     1441 gggcttactt gggactggat tttgatttat agtggttggc tcattttctt tcatcctgtg
     1501 ctattgacct atctttcaaa ccaactttgt gaccacttta gtcaactcta ttcccagatt
     1561 agaccgagat tctggcgttt tgctttacaa attctcctat gggatagcct gatgattctc
     1621 tccttggtgt ctttaagtga tattccactt ttccttcagg gaactctcct catcatagga
     1681 catctcatcc cttcctatcg catctgccaa agcctgaaaa gagacttccc ccaagcatat
     1741 caagaaccga tttctttttg gagtatttta tgatcgatga gaaagaccaa gccgactggg
     1801 cttggtcttt cttatctctt tttagtatct aggataatgg taacaggtcc gttattaacc
     1861 agctcaacct gcatatctgc tccaaagata cctgtctgaa cgggcacttc ttgcgctaat
     1921 ttttgattga aagcatcata gaagtctgat gccatatcag gtttagctgc ccctgtaaag
     1981 gctggacgat tgcctttctt agtatccgca aagagggtaa actgagaaat agagaggatt
     2041 tctccttcaa tatctttgac agacaggttc atcttgcctt ctgcgtctga aaaaatccgc
     2101 atattgacca gttttctcac agcatagtcc aaatcttcct cttggtcctc tggtccaaca
     2161 ccaaccagca ataaaagtcc ctgattgatt tttccctgaa tctggccttc tatactcact
     2221 tgggcttttt taacccgttg gataatgatt ttcataatag cctttctagt aagagctagg
     2281 acaactagcc gttggtccgt ttgacagagt aaacttctgg cacactctta attttatcga
     2341 caaccgtggt cagtgtagag aggttggcaa taccgaagga cacatggata ttagcaaact
     2401 tcatatcctt ggttggttgg gcattgaccg ttgaaatatt cttggttgta tttgaaagaa
     2461 cttgcagtac atcgttcaac agtcctgtac ggttgagacc gtagatatcg atatgggcca
     2521 tatactcctt atttgagcta gagtactggt cttcccattc cacatcaagg agacgttgct
     2581 cgtagttttc ttgggcacgc aggttcatac agtccacacg gtgaatagcc acaccacgac
     2641 ccttggtaat gtagccaaca atatcgtcac caggtacggg gttacaacac ttagcaatcc
     2701 gcactaggag accagaagca ccttcaataa ccactccccc ctcatgcttg accttgagag
     2761 tttctttatt ttcaaccttg acctcgccac ctttgacaag ctcctctgcc tcagccttgg
     2821 ccttggcacg ctcttcctca cggcgctcct tttcagtcag acggttaaag acggtaatcg
     2881 caccgatttc cccaaaacca atggccgcaa agagggagtc ttctgtcttg taactggtct
     2941 tttgcagaac ttgatccatg tggcgcttgt ccataaattt atttgccaca tagccatttt
     3001 cttggaactg agccatcagc atctcacgac ccttgttgac agacaattcc ttatcttggt
     3061 ttttaaagaa ctggcgaatc ttattgcgcg ccttgctagt cttgaccata ttgagccagt
     3121 cacggctagg tccaaaggag ttcgggttgg cgataatttc aacctgatcc cctgtcttta
     3181 acttggttgt cagtggaacc atgcggccat tgaccttggc accagttgct ttttcaccga
     3241 ccttggtatg gatttcgtag gcaaaatcaa tcggtcctga atctttggga agggaacgga
     3301 cagctccatc tggggtaaaa acgtaaatct cctcagccag atagttttcc ttaacagagt
     3361 ccacaaattc cttagcatca tcagcctggt cttggagctc catcatctcc ttgatccagt
     3421 tcattccaat agctgattcc ttgctgttaa cttgcccctt tatacctttc ttataagccc
     3481 agtgagccgc aaccccgtac tcagccacct cgtgcatttc cttggttcga atctggaatt
     3541 caatcggccc ttttggccca taaacagtcg tatggataga ctgataacca ttggccttgc
     3601 ggttggcaat atagtctttg aagcgacctg gcatcggttt ccaaaattca tgcacgtaac
     3661 caagcatggc ataaacatca ctttgggtat ctaaaataca acgaatagca atcagatcat
     3721 agatttcctc aaaccgtttt ctcttgtcct gcattttgcg gaaaattgag taaatatgct
     3781 tgggacgacc ataaatattc cctttcaagt gacgttctgt cgtatactcc tctaattttg
     3841 tgactacctc atccaccaag acctcacgct ccctgcgctt ttccttcatc atatgggtaa
     3901 tcttgtaaaa ctccgttgga ttgagataac ggaaagacaa gtcttctaat tcccatttga
     3961 cactggaaat ccccaaacga tgggcaagtg gggcatagat ttccatggtt tctttggaaa
     4021 tacgctcctg cttgtctttt cgaagatgtt tcagggtccg catattgtgc aagcggtcag
     4081 acagtttgac caaaataacg cggatgtcct cagacatggc catgagcatc ttgcgatgat
     4141 tttccgctaa ttgctcctcg atcgatttgt actcgacctt gccaagcttg gtaactccgt
     4201 caacaatcac ccgcacatca ggaccaaact ctctttccaa atcgtccaag gtcgcatctg
     4261 tatcttccac cacatcatgc aagaatccac aagctactgt tacagcatcc agctttagct
     4321 tagctaaaat acctgccact tggatagggt gaatgatata aggctcgcct gatttgcgat
     4381 attgaccact gtggcattca acagcataga ccaaggcctt atggacaaaa tgaacatcct
     4441 cttccgttaa atattctttg gttaaagcga caacttcttc gcctgttaaa ttcacttctt
     4501 tcggcatctc tactctccaa ttcttcctac cattttatca cttttttaag aatatgaaaa
     4561 ctagattgga acagaataag aaaaaaataa ttcaaaattg cttgataatt ctgaattatt
     4621 ggcccataat atactacgaa gttagatttt aaacttaggt gatagaagga gagatagaag
     4681 aacggaaacc atattgtaac ccaaagactt tctgatttcc ccaattccat tgaagatacg
     4741 aaagataaac ggtggaactc gtatcacata cactggtacc ttgactggat tttggaatta
     4801 atactcaatg aaaatcaaag agcaaactag gaaactagcc gcaggttgct caaagcactg
     4861 ctttgaggtt gtagataaga ctgacaaagt cagtcacata tatacggcaa ggcgacgttg
     4921 acgcggtttg aagagattgt tgacgcggtt tgaagagatt tttgaagagt ataaaaatcc
     4981 tcaagatact ttcttctatc ctttagttta taaggagaat acctatgaaa aaaactgcta
     5041 tttctatctt tgctctccta atgttaggag tttgctgcct gttcctattc agccagcaaa
     5101 gctataaaaa actcgttcaa tactatgcta acgaccagaa cctgcccagt aggataactt
     5161 atagtgaata tagcgacaaa tgataagcca actacggtag cactctaaac atcacgtcta
     5221 tcaaacaagc taatgacgga gtttatgcaa cctatgaagg gcaattgaca cctttccaat
     5281 attgataaat tgataaccag cctgtcttca tctagtcatg ctggttttta agttcatttt
     5341 aaatccttac ctattctccc taactgtgct atacttaatt tatactcaat gaaaatcaaa
     5401 gagcaaacta gaaagctagc cgcaggctgt tcaaagcact gctttgaggt tgcagataaa
     5461 gttgacgcgg tttgaagaga ttttcgaaga gtattagtac attctttgag attggagcta
     5521 gtatgaaaat ccataaaacc gtgaatcctg ttgcctatga aaatacctat tatctagaag
     5581 gcgaaaagca cctcatcgtc gtcgatcctg gtagtcattg ggaagccatt cgtcagacaa
     5641 tcgagaagat caacaaaccg atctgtgcta ttctcttgac ccacgcccat tatgaccata
     5701 tcatgagtct ggacttggtt cgcgagacgt ttggcaatcc tcctgtctat atcgcagaga
     5761 gcgaagccag ctggctctac actcctgtcg ataatctctc cggtctccct cgccacgatg
     5821 atatggcaga tgtggtcaca aaacctgcag aacacacctt tgtctttcac gaagaatacc
     5881 aactagagga atttcgtttt aaggttctac cgaccccagg gcactctatc ggtggtgttt
     5941 ccctagtctt tcctgatgct cacctagtct tgacgggaga tgctctattc cgcgaaacta
     6001 tcggacggac cgaccttccg actggtagca tggagcaact ccttcatagt atccagaccc
     6061 aactcttcac cctaccaaac tacgatgtct atccaggaca tggtccagct actactatcg
     6121 ctcacgaaaa ggccttcaat ccctttttct agcaagatga tgacaatcga aatttaagta
     6181 aactatccag caaatctttc tattacaaaa ggcatcctat caaggttttc acacgtgatt
     6241 ggatgccttt tttctgatga ctagattttt tgtattacca aataatcacg cgctcctctg
     6301 gtgaacgcca cattccgtct ccttctttga catcataggt tgtaaagaaa tcgtcgaagt
     6361 ttggtacttg cacattgaca cggagtttgg ctggtgcgtg cacatcgacg ctagccaaaa
     6421 gtttcataaa ttctggtcga cctttcatgc gccagatgcg accgaagttg tagaagaact
     6481 cttctgctga gaagtctgct tctctcttag ctgcttcaag cgctgctgcg attcctccca
     6541 agtcagccac gttttctgat acagtcaatt taccgttaat ggttgctcca taagaatcct
     6601 gtccatcaaa ttggtcaatg actttttgtg ttttctcctt gaaggcagca tagtcgctct
     6661 ctgtccacca atccttgagg ctaccatttt cgtcaaagga agccccgtta gtatcaaagg
     6721 cgtgggaaat ttcatgggca atcactgccc caataccacc gtagttagca gaagatgact
     6781 gatgcaagtc atagaaaggc gcctgtaaaa tggccgctgg aaagacaatc aggttcttct
     6841 gaggattgta gtaggcattg accatatgag caggcatgcc ccattcctta tagtctacag
     6901 gctggttcca cttactccaa ctgtgcttga tttccacacg cgcaaaggct agagcattct
     6961 caaaaagact ggcagtttca ttcactacct tatccttgta acgtgcaggc aattcttctg
     7021 gatagccaat ataaggtttg atcacattga gcttcacgat agcctgttta caggtttctg
     7081 gagtgagcca gtcattctta agcagacgct ccttatagac atcaatcatg gttgccactt
     7141 ttttctccac atccgccttg gcttctggag agaacttctc acgggcgtac caaagaccca
     7201 gggcttgctt gaaaggttct tgtgctagat gataagctgc tttgacctta tcttttgcct
     7261 ctggaactcc agaaagggca cggctgtagg caccagacaa aacacggata tcctctgtta
     7321 aatagctggt tgaaagattg acaacactca aaatcaaggt tgctttaagg agagaccagg
     7381 cttcctcact gtagaattgc tctgctgctt gccagaaacg ttcctcgtct acaataacct
     7441 tgtctggtaa ttgcccaata actgctttga agaagtcatc caaaggtagg gcaggcgcga
     7501 atttcttaaa atcttcgtaa gaatatggat gatagagttt agcatattct gaactttctt
     7561 cattagagag caccactgcc gcaactcggc ggtccaattc aagtcttttt tctagcaagt
     7621 cttcaatttc ttcatcagag aaatcataag ccttgaggag atttgcgctg ctttctttcc
     7681 aaagagtcaa gagctcttcg cgctgaggat gttcttctgc atagtaggtc gtatctggca
     7741 agattgtgct tggagcgcta gcccatagaa cattgattct agcatccata aagtctggcg
     7801 atacaccaaa aggaaggaag tttggttttc ctgcaagctc aaactctgct agtttagctg
     7861 taaaatccgc aaaagtttcc aattcttgga attctttaag gagtggtaag acaggtgtga
     7921 taccgtcagc ttctctcttg tcaaaatcac gaactaggcg gtggtatttg acaaagtttt
     7981 ccaagatagc atcctcaggc acttcttcac ctgctaacca cttgtctgtt gtcgccagca
     8041 tcaggtcttc aatttcctgg tctaaatcaa caaaacctcc agtttgagac ttatctgctg
     8101 ggatttcagc tgtctgttgc cattctccat tgatagcatc ataaaaatca tcttgataac
     8161 gtgtcatctt gttctcgctt tcatttgtat ttgcatttat cttaacaaaa atcactaggg
     8221 aatgcaatta ataaccattt aactattatt ttttagctat tataaaaaat ctttccatga
     8281 taaaacgcat
//
LOCUS       DAVMAH010000072         8248 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVMAH010000072 DAVMAH010000000
VERSION     DAVMAH010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8248
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.072"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..161
                     /locus_tag="VYO94_001874"
     CDS             <1..161
                     /locus_tag="VYO94_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV1760455.1"
                     /translation="IEKKIMNYIFEDDGNVSEVIGALDIIHHLDKIAHTTQSIYKWIM
                     YRKYGNIN"
     gene            174..1649
                     /gene="galT"
                     /locus_tag="VYO94_001875"
     CDS             174..1649
                     /gene="galT"
                     /locus_tag="VYO94_001875"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1760456.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEENAIADYHLEWADQLKEKYPRINKEEVN
                     NVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1662..2672
                     /gene="galE"
                     /locus_tag="VYO94_001876"
     CDS             1662..2672
                     /gene="galE"
                     /locus_tag="VYO94_001876"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1760457.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            2856..3515
                     /locus_tag="VYO94_001877"
     CDS             2856..3515
                     /locus_tag="VYO94_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV1760458.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRVTEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVRFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3540..4607
                     /locus_tag="VYO94_001878"
     CDS             3540..4607
                     /locus_tag="VYO94_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1760459.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIPGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSISGLQGGTGRAILASILVRYLDDKGELGVSEKGWEVAKEYLKNAYTL
                     QKGESSIVKMLDKEDPIQYGMMWGSGALVGQKEQNVVFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKNFGSIPANKDALKDLPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            4710..5720
                     /locus_tag="VYO94_001879"
     CDS             4710..5720
                     /locus_tag="VYO94_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760460.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5732..7423
                     /locus_tag="VYO94_001880"
     CDS             5732..7423
                     /locus_tag="VYO94_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1760461.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7426..8136
                     /locus_tag="VYO94_001881"
     CDS             7426..8136
                     /locus_tag="VYO94_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV1760462.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2791 a         1145 c         1618 g         2694 t
ORIGIN      
        1 atattgaaaa gaaaataatg aattacatat ttgaagatga tgggaatgtt tctgaagtaa
       61 ttggtgcttt agatattatt catcaccttg ataaaattgc tcatactacg caatcaattt
      121 ataaatggat aatgtataga aaatatggga acataaatta gaaagaaaaa tatatgaaaa
      181 caattattga taattttgtt gatagagtaa ttgaatacgg aatgtataat gaaattgaca
      241 aaatatatgt gaaaaataga gtactagcgt taataggtga ggagggaact gatcgcattt
      301 ccgatgaaaa tgacctgaaa caaataaaag attacttagt ggaaatcgcc ttaaaaaacg
      361 gtaaaattaa agatttaatc gaggaaaagg aatgtttagg agcagagtta atgaatttca
      421 tagttccttt acctagtcga ttaaatgata ttttttggag ttcatatgat atatcacctc
      481 aagaagcagt tgaagagttt tataagttaa gtaaagatag tgattatatt aaaacttctg
      541 ctattgctaa gaatattgag tttcgagcat caactaaata cggagagcta gagattacga
      601 taaatttgtc aaaacccgaa aaagatccaa aaacaattgc tgctgaaaaa ttagtaaaag
      661 ccactaatta tcccaaatgt ttactatgta tggaaaatga aggatatcag gggcgaataa
      721 attatccagc acgttcgaat catagaatta ttcgattgaa acttggtgac gaagtatggg
      781 gattccaata ttctccctac ttatacttta atgagcatgc gatattttta aatagtcaac
      841 atgtaccaat ggctattacc tctaaaacat ttgaacaatt attggagatt gttgatattt
      901 tgccaggata ttttgctggt tcaaattctg atcttcctat ctcaggaggc tccattctta
      961 gtcataacca ctaccaggga gggaaacata ttttcccaat ggaaaaagca aaatttgaga
     1021 gtgaatttcg ttttaaagac tttgaggatg ttaatgctgg tattgtaaaa tggccaatgt
     1081 cagtaattag gttacaaagt gaaaataaaa atcgcttgtt agatttagct actaaaattc
     1141 taaataagtg gagagaatat tcagatttag aagtagacat cattgctatg actgaagatg
     1201 tcccacacca tacggtgact cctattgctc gtaaagtgga cgggagatat gaattagata
     1261 ttgttctaag agataatcat actactgaac agtacccaga tggtgttttc catcctcatc
     1321 aagatgtaca acatattaaa aaggaaaata tcgggttaat cgaagtgatg ggacttgcga
     1381 tattaccacc tcgtttgaaa ccagagttag aagaagtggg aaaatatctt ttaggagagg
     1441 aaaacgcaat tgcggattat catttagaat gggccgacca attgaaagaa aaatatcctc
     1501 gcattaataa agaagaggtt aataacgtag ttcaacacga agcaggacaa gtgtttgcga
     1561 gagttctgga agatgcagga gtttataaga atacaccgtc tgggcatgaa gcgtttatga
     1621 gatttgttaa gtcggttgga attaattagg aggaaaccca aatggcaata ttggtaacag
     1681 gcggagctgg ttatattggt agccataccg tagtagaatt actaaattta ggaaaggaag
     1741 tcatcattgt cgacaacctt tcgaactcta gcatcttggt gctagaccgt attgaagcaa
     1801 ttacaggaat acgtcccgtg ttttacgaat tagatgtttg tgataaacaa gcattgagaa
     1861 aggtatttga acaagaatcg attgatgctg caattcattt tgcaggttat aaagctgtcg
     1921 gagaatccgt gcaaaagcct gtgatgtact acaaaaataa tattatgagt acattggcac
     1981 ttgttgaagt gatgtcagaa tttaatgtta aaaagattgt cttttcttca agtgcgactg
     2041 tatatggaat taacaatcag tcacctctaa ttgagacgat gcaaacaagt gcgacaaatc
     2101 cttatgggta tacgaaagtg atgcttgagc aaattttaaa agatgttcat gtggcagatt
     2161 cagaatggag tattgcgttg cttcgttatt tcaatccaat tggtgctcat gagtctggtt
     2221 taattgggga agatccctca ggaattccta acaacttgat gccttatatt gcacaagtag
     2281 cggtaggtaa gctgtcagag ctaagtgtgt tcggaaatga ttatgatacg cttgatggta
     2341 ctggtgtgcg tgattatatc catgtagtag atttagcaat aggacatata aaagctttag
     2401 aaaaagtatc tgaaaaaaca gatgtttata tctataacct aggctcggga gaaggcacta
     2461 gtgtattaca acttgtaaat acatttgaaa gtgttaataa gatccctatt ccttataaaa
     2521 tagttccaag acgttcagga gacgttgcaa cttgttatgc aaatgcagac aaagcatata
     2581 aggaattaaa ttggaggaca acaaaatcga ttgaagacat gtgtagagat acatggaatt
     2641 ggcaatcaaa aaatcccaat ggctataatt gatgatactg tttatatgag tgctgtattt
     2701 tggaaaaatt acttaacctt ttaatgaaat tcatatttaa tgaaagataa atttttttaa
     2761 aaaaattttt gaaagcgctt gacaaaggaa acggtttcat tgtataatgt aaacatgatg
     2821 acaccgatgt caaatataaa aaagaaggtc tttatatgaa aaacttaaca aaaattaagt
     2881 tcaaagagaa tggggaattt aatcatttcc ctgggaatac agttgtagca aatctttata
     2941 ctaaacaaga tttgatggaa gttgttgata ttattcaatc acgttataga gaattaccat
     3001 ttatcgataa gtttacttta actccaagga attctattca catgactgta attgaattgt
     3061 tgtgccatga aaatcgtgaa acggagtttt ggagcagtaa tcttcctcta gatacacctt
     3121 tacaggaaat acacgattac tttgctaaac aacttgaaat ttttccattg ttggatgaag
     3181 aaattcatat gcgtgtaact gaaatgggaa aacaaaacat actagttgaa cctgcagatg
     3241 aagcttctgc aaagagatta gaagaaattc gtacttatgt ctcagaaaaa gcaggtgttc
     3301 gtttccctaa tcatgataga tatcaattcc atatttcaat tgggtatctt cggattcctc
     3361 taaccgaaga ggaggaagaa gagtttacta aagtcagagc agaattaact gaaattttat
     3421 tagagaagat tccaactatt actgtaaacc gtattgacta tactgtattt gaagatatga
     3481 gacaatttgt tccatatcac gaaaaattta aataaaataa taaaaaagga gaacttatca
     3541 tgaaaaaaat gaaagtttgg tctactgtac ttgcaacggg agttgctctt actacacttg
     3601 ctgcttgctc tggaggttca aattctacga ctgcttcttc atctgaagaa aaagctgata
     3661 aaagtcaaga actagtaatc tattcgaact cagtctcaaa tggtcgtggt gattggttaa
     3721 ctgctaaagc aaaagaagct ggttttaata tcaaaatggt tgatatccct ggcgctcaat
     3781 tagcagaccg tgttattgct gagaagaata atgcagttgc agatatggta tttggaattg
     3841 gtgctgttga ttcaaataaa attagagatc aaaaattact agtacagtac aagcctaaat
     3901 ggttagataa aattgatcaa tctttatcag ataaagataa ttattataat cctgtgattg
     3961 ttcaaccatt agttttaatt ggggcgcctg atgtaaaaga aatgcctaaa gattggactg
     4021 aattaggtag taagtataaa ggtaaatatt caatttctgg tcttcaagga ggtacaggac
     4081 gggcaattct agcaagtatc ttagttcgat accttgatga taaaggtgaa ttaggtgttt
     4141 ccgaaaaagg ttgggaagta gcaaaagaat atttgaaaaa tgcatacact cttcaaaagg
     4201 gagaaagttc aattgttaag atgttagaca aagaagatcc aatacaatat ggaatgatgt
     4261 ggggttctgg tgcattagtt ggacaaaaag aacaaaatgt tgttttcaaa gttatgactc
     4321 ctgagattgg tgtaccattt gtaactgaac aaactatggt tttaagcact agtaaaaaac
     4381 aagcgttagc taaagaattt attgattggt ttggtcaatc agaaattcaa gtagaatata
     4441 gtaagaactt tggatctatt cctgcaaata aagatgccct caaagatcta ccagaagata
     4501 ctaagaaatt tgttgatcaa gtgaaaccac aaaatattga ctgggaagct gttggaaagc
     4561 atttggatga atgggtagaa aaagctgaat tagaatacgt acaataagaa ataagagtta
     4621 atttttatgt ccaagtctct ctattatttc taaatttatg gaagaaataa agagaggctt
     4681 ttggtttagt aatagaggga gttagtgaga tgattaaatt tgataatatt caaattaaat
     4741 atggtgattt tgttgcaatt gataatctga atttagatat acatgaaggg gaatttttta
     4801 catttcttgg gccttcagga tgtggtaaat caactacttt gagagcattg gtaggttttc
     4861 tagatccatc atcaggaagt attgaagtta atggaacaga tgtcactcat ttggaacctg
     4921 aaaagcgtgg aattggtatt gtatttcaat cttatgcgct atttccaact atgactgttt
     4981 ttgataatat tgcatttggt ttaaaagtta agaaggtagc tccagatgtt attaaagcta
     5041 aagtatcagc agtggcagca aaaattaaga tctctgatca acaattacag cgtaatgtat
     5101 cagaattatc tgggggtcaa caacaaaggg tagcattggc tcgtgctctg gttcttgaac
     5161 ctaaaattct ttgtctagat gaaccattgt caaaccttga cgcaaaatta cgtgtagatt
     5221 tgagaaaaga gttgaaaaga cttcaaaaag agttaggtat tactacttta tatgttactc
     5281 atgatcaaga ggaagccttg actttatctg atagaattgc agtctttaac aatggataca
     5341 tcgaacaggt cggtacacca gtagagattt atcataattc tcaaactgaa tttgtatgtg
     5401 attttattgg agatattaat gttttgaccg atgaaacagt ccacgaagta ttattgaaaa
     5461 atacaagcgt tttcttagag gataaaaaag gatacattcg attagagaaa gttcgattca
     5521 atcgtgaaac tgaacaagat tttattctaa aagggacaat tattgatgtt gagttttctg
     5581 gagttacaat tcactataca ataaaagttt ctgaaagtca gattcttaat gtaacaagta
     5641 ttgatagtca ggctgctatt agatctgtcg gagaaagtgt ggaattattt atcacaccat
     5701 cagacgttct gcaattttaa ggaggtgcag tatgcgtcat aaattaaatt taaaagattg
     5761 gcttattcgt ttagggttaa tctggttctt agtaacattt attatttatc caaactttga
     5821 tctagtagtg aatgtatttg taaaaggagg agaattttcc cttgatgctg tacatcgtgt
     5881 tctaaaatct cagagggcac ttcagagtat tatgaacagt tttaagttag cattttcact
     5941 cattattaca gttaatgtcg taggtattct ttgtgttcta tttacagagt actttgatat
     6001 taaaggtgct aaaattttaa aattaggtta tatgacctct ttaatttatg gaggagtggt
     6061 tttagcgact ggatataaat ttgtctatgg tccttatgga ttgattacaa aatttttaca
     6121 aaatgttatc ccttctttag accctaactg gtttattggg tatggtgcag tcttattcat
     6181 tatgacattt tcaggaactg ctaatcatac attgttttta acaaatacaa ttcgaagcgt
     6241 tgactatcac actattgagg ctgctcgaaa tatgggagca aaaccattta ctgttttccg
     6301 aaaagtagtg ttaccaacct taattccaac tctatttgca cttactatta tggtttttct
     6361 tagtggttta tctgcagtag cagcacccat gattgttggt ggtaaagaat ttcaaactat
     6421 aaatccaatg attattacat ttgcagggat ggggaattct cgtgatttag ctgccttact
     6481 tgcaattatt ttaggtattg caactacaat tttgcttact atcatgaata agatagaaaa
     6541 aggtggaaat tatatttcta tctctaagac taaagcgcct cttaaaaaac aaaaaattgc
     6601 gtctaagcct tggaatatca ttgctcacat tgtagcatat ggattgttca cagttttcat
     6661 gcttccacta atttttatag tattatactc atttacagat ccagttgcaa ttcaaacagg
     6721 taacttaaca ttatcaaact ttactttaga aaattatcgc ttattcttta gtaatagtgc
     6781 ggcattctct ccattcttgg tcagctttat ttattctatt attgctgcga caacagcaac
     6841 aattctcgca gttgtatttg ctcgtgttgt cagaaaacat aaatctcgtt ttgatttctt
     6901 atttgaatat ggtgctctac ttccttggtt actaccaagt acacttttag cagtaagttt
     6961 attatttact tttaatcagc cacaatttct tgtcttgaat cagattttgg taggtagttt
     7021 ggtaattcta cttattgcat atatagttgt aaaaatccca ttttcttata gaatggtacg
     7081 tgctatttta tttagtgttg atgatgagat ggaagatgca gcaagaagta tgggtgcttc
     7141 acctttttat actatgatga aggttatcat tccatttatt ttaccggttg ttctctctgt
     7201 tattgcttta aactttaact ctttattaac tgacttcgac ttatctgtat tcctttacca
     7261 tcccctagct caaccattag gtattacgat tcgatctgca ggtgatgaaa cagcaacatc
     7321 taatgcacaa gctctggtat ttgtttatac aattgttctg atgattattt ctggaacggt
     7381 attatacttc acacaaagac cggggcgtaa agtaaggaaa taatcatgac agccactagt
     7441 cttgggttat caaatattga aatagttgtc aggattgttt tatcagtagt cattggtagt
     7501 ataattggtt tagagagagg gagcaaatcc cagcctgcag gcatccgaac ttatagtatt
     7561 gtttgtctag ctgcatgttt gattatgatg acgaatgaat acgtatctta taaatttggg
     7621 acaggagatc ctacacgatt aggagctcaa gttatatcag gtgtgggttt tctaggcgct
     7681 ggaacgattc ttattacaga taaaaagaaa attacaggtc tgacaactgc agcaggcatt
     7741 tgggcttcgg caggaattgg attagctatt ggagtaggtt tttatgaggg agctctttta
     7801 gtagccattt ctgtttgggg tgtgatatcc atgttccaac cactaaaaaa atatctgcaa
     7861 aatcgttcta aaatgattga attgtatata gtagttaaat ctacagaagc ctataatcgt
     7921 gtattggttt attgtgcaga aaatggtatc agaatgaccg attcaagaac agcgtttgga
     7981 gatgttaatt ctgacagaat tgaatacttt gatgttccgg acaaaaaaat agcgtcattt
     8041 attactctgg aattatcagg tagatttgaa catcttcgac tgatggaaga aattgctaat
     8101 attgtaggtg ttatttatgt cgaagaaatt agctgaaatt tagtaaacaa agggacagat
     8161 gtttttgtcc ttttgttttt tagatgtttt aatcatctaa tttttgagta gatttttgct
     8221 cagaggtttt tatgaaagat tataaaat
//
LOCUS       DAVMAH010000073         7277 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVMAH010000073 DAVMAH010000000
VERSION     DAVMAH010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.073"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            145..831
                     /locus_tag="VYO94_001882"
     CDS             145..831
                     /locus_tag="VYO94_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1760463.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            832..1764
                     /locus_tag="VYO94_001883"
     CDS             832..1764
                     /locus_tag="VYO94_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1760464.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1775..2704
                     /locus_tag="VYO94_001884"
     CDS             1775..2704
                     /locus_tag="VYO94_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1760465.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2718..4157
                     /locus_tag="VYO94_001885"
     CDS             2718..4157
                     /locus_tag="VYO94_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760466.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4226..5803
                     /locus_tag="VYO94_001886"
     CDS             4226..5803
                     /locus_tag="VYO94_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1760467.1"
                     /translation="MVKLNKVLKGSVALLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDQTLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSKHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5866..>7277
                     /locus_tag="VYO94_001887"
     CDS             5866..>7277
                     /locus_tag="VYO94_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1760468.1"
                     /translation="MYDVVVIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIEKGGTVFSSMEELMNVSDFYQITIPYQPE
                     VYESVLTEMLNESNVDILLNVEINNIVFDNNKIHSVEIISNQEVNYLESKVFIDATGN
                     ATIASASGANVYEKNSSYGCLMRVGGVDITKTLEHIEKTKQWEFEEGYNEWLDNVLAN
                     RKYRATGAVLRDPVSYDHAPMLTKDDHFMNEEKWSYIKERWERFGFIYTLEVSLFRNE
                     LREAVEAGDFEFEIYHDDESGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKS"
BASE COUNT         2497 a          990 c         1393 g         2397 t
ORIGIN      
        1 gcattaaatg ctaaaatatt tctataaatt aatttaactt tcctgatagg gctgttcata
       61 tcttatttca attcactata taaataaaat tgtagtagat gttattgaat tagtaaaaaa
      121 aataaaaaaa cggaggtttt ctgaatggaa actaaaaaaa ttaaaaattt aaaaggtcaa
      181 ataattgttt cctgccaagc gttagaagga gagccacttt atactccaaa tggaggagtg
      241 atgccgttat tagcaaaagc cgcctttcaa gcaggcgcta aaggtattcg tgctaattct
      301 gtccgcgata tttcagaaat aaaagaagaa gttgacttac caattatagg tatcataaaa
      361 agagattacg atggctttga accttttatt tcagcaacta tgaaagagat tgatgaatta
      421 gttagtgaag gagtagacat tttagctttg gattgtacta atcgttcaag accaggttat
      481 gataatatta ctgactttat tcatgatatt aaagtcaagt atccaaacca attattaatg
      541 gctgatattt ctacttttga agaagggaaa gtagctgctg aatcgggagt agattttgtg
      601 ggtacgacat tatctggtta tacaccatat agccctaaaa aagataatcc tgattttgag
      661 ttagttgaaa gattggtaaa agagcttgac gtaccagtta ttgctgaagg aagaataagt
      721 actccggaac aagctagaaa aatgttagat ttaggtgctt acgcagtggt tgttggagga
      781 gctatcactc gtcctttgga aatagcgaag aagtttattg aggtagttta gatgaatcaa
      841 gaaatattaa aaaagagtaa gattcaattg acagttgaac atattcaaaa atattggatt
      901 ttatatttaa tgatgattcc agcaactgtt ctactaattt tatttacgta tggaccaatg
      961 tacggcatta ttatggcctt tcaagacttt actgtcttca agggatatac tggaagtcca
     1021 tttgtcggtt taaaacattt tcaaagattg ttctcagatc ctttgtttta tagattgttc
     1081 aagaatacgt tcatggtagg ggttttagac tttttattct ctttcccagc tccgcttatt
     1141 tttgcactca tattaaacga agtcagaaaa gtaagattta agagtgtagt tcaatctatt
     1201 agttatcttc ctcattttat tcccctagtg gttatggttg gtattatttt tgaactattt
     1261 ggttcatatg gtattattaa cagtttactt tcatcacttg gaatggagcc aataagtttc
     1321 tttacaaaat ctgaatggtt cttgcctctc tacattggtt caggagtatg gaaaacaata
     1381 ggttggggtt ctatcattta tatgggagca ttaaccaata tagattcaac tttatatgaa
     1441 gcagcagata tggacggggc taatagatgg cacaaaatgt ggcatgtaac tctaccaagt
     1501 ttaagaccta cagtagttac tttgtttata ctaaatgctg gtggtatcat gcaagtagga
     1561 tttgaaaagg tattcttgat gtctagtcct gcaacatatg aagtatctga tgtattatct
     1621 acttatgttt atagacaagg tattttaaat tctgatttca gttactcagc tgcagtagga
     1681 ttatttaata acatagtagc tttgttattt gttttattag ctaataagat tgctaaaaaa
     1741 cttggcgaag aaggaattgt ataagggggg taaaatgatt ttttcaaaaa atacaaaaaa
     1801 gagtaataga gacaaagaaa ccttcgttga ttatctcttt atattcattt taataataat
     1861 aaccttactt atgttgtatc cattatggtg ggtagtgatg acgtcacttt cagaaccagt
     1921 ttggctatct aaaaacgttg ttaaattatt tcccttaaaa atagatatta ctgcatataa
     1981 gtttattttt ggggattcta aactatggca agcatatggt aatagtgtat tgtatgctgc
     2041 actatctaca attgttagtg ttgcggtatg tagtatgtat gcctatccac ttacaattcc
     2101 tgaaattagg ggtaaaaaat tctggaatac tcttattttg attccaatgt tctttagtgg
     2161 aggaatgatt ccgctttata tacaagttgc aaacctcggt ttattgaata ctgcttgggc
     2221 tcttgtttta cctggtgctg tttctacata ttatataatt ttgtttagaa cacagtttaa
     2281 atcaatccca atggagcttc gtgagtctgc tagaattgat ggggcaagtg aatttagaat
     2341 tttttggaat ttagtattac cattatcaaa agttattttc atgattatag cactttattg
     2401 catagttggt tcatggaata gttttactcc tccattactt tatttgaatg acgacactaa
     2461 gatgccttta tctatttatt tgagaaattt agttgttaca aatacaactg atactgctga
     2521 attatcactt tctgcaggta atacatatta ccaacaaatt gctgctcaag gtggaggtat
     2581 tggtatgcgt attgctatta agatgggtac tattgttgtt agtgttattc caattatgat
     2641 gatttatcca tttattcaga aacattttgt taagggaatc ctgctaggtt ctgtgaaagg
     2701 ttaataaggt aattattttg caaaatttaa aaaaatatct tttattagat agcggtttag
     2761 tagttgggta tacattagaa aatgctcaat taaaattaaa taagctaaaa aaagatactg
     2821 aaaacaatcc actatttggt gaagagtatt ttgccgaaaa tcctaaatta tgggaagttc
     2881 gttttgataa ttcatatcca aacgttatct atgataaaga attgaaatta tatagatgtt
     2941 ggtatcaaac atttgttagt gatgaagcaa gcgaagagac tcctttagca gaacgtggag
     3001 agaaggaata cattgtcaag tcatctagaa tgacagcact ttgctatgct gaaagtaaag
     3061 atggagtaaa atgggaaaaa ccaaatctca atctagtaaa atttaaaggt tcaaaagata
     3121 ataatattgt tctgatgcat gcacacggtg caggtatcat gctagatgaa caggagttgg
     3181 atcctaagaa acgatataaa ttagtttcaa aattagaatt ttctccgaat cttcattaca
     3241 tggttgttgt tttttcagaa gacggtattc attttgacga acctattcca tggaaaaaat
     3301 ggaatcctgc agcagatagt cataattttc catttagaga tccaaaaact ggtaaatacg
     3361 ctgttattac aagaacctgg gcaaataacg tacgtctaag tgcaattact ttcagtgatg
     3421 attttattaa ttggtcagaa cctaaagaaa tccttagggg agatggattt gaagatcaaa
     3481 tttattctat gccagtaatt tcatacgcgg atatctattt aggttttgct tcaatgtacc
     3541 acgaaggcga cactttaaat gaaaactatg ataaagtaga cttagaattg aaattctctg
     3601 ctaatttgga acaatgggat agtgtatgta agggcgacta tctcattgaa aggggaggtg
     3661 gagtataccc gcagaatgct gattttgatg ctagttgtat tttcacggct gctccaataa
     3721 ttgaagatga taagatttgg ttctactata tgggtggaaa tggtaatcac actggcttcc
     3781 gagaaagttc attagctaga ggatatatta agaaagacca atttgcttat tatactaata
     3841 agagagaagg aattccagct aaaatatcta cagttagctt ccaaacttac gatgatgaaa
     3901 tttatatctt agctgatatt cctgaaaatg gttatattaa agttgcggta ggtactaaat
     3961 acggtaatgc ttattcagat tttggtcagg aagatatctc tcttgttcaa gtttccgatg
     4021 gtaagtataa gttggaattt aataaaaaat ctatcttaga tttaggtaat tctccagttg
     4081 cgttcaaatt tgaaatcgag aatgcaaaat tgtatggtat tgaaggtagt attcagcaac
     4141 actatctcaa atattaacca gaataattcg ttaacaaata atctctatat tagtggagat
     4201 agatatataa aatggaggtc ttattatggt aaagcttaat aaggtattaa aagggagtgt
     4261 agcactcctg agtgcaagtt tattgctagc agcttgtggc aataacgcta attcaaagcc
     4321 tgctgaaaaa acagctgatg gtaaaacgaa aatttcgttt ctatctacat ggcaaattaa
     4381 tgatgttcgt ccacctaaag atcaaacact tgttggtcag tggttagaag aacagctagg
     4441 tattgatatt gatcttgtaa ctattcctgg cgagggagta agttctaaag taaattctct
     4501 tattactagt aaccagttac cgactgtttt gttgacaaca ggagataaga gtgatatcgc
     4561 tggtatcaac aaacttggta aacagggtgc attcttagat ttgtcaaaac acatggacaa
     4621 actaccaaac tataagaagt accttgaaaa aaataatgca ttagctcaaa tagaagatga
     4681 tgaaaaacat atttatgctt tcacaaaatt ctttactgat gagaatatca tgtatactac
     4741 accaattctg agaaaagact tacttgttgg ttcagaattt gaagatcttt caaaaattaa
     4801 aactgttgat gactatacaa aagttttgaa atatttgact gaaaaacaag gttctccagc
     4861 atttattcaa cgtaatggct atgaaggctt catgaagcga gttacaccat tgtggaattt
     4921 aagccatcgt acatactatg actatgaatc agattcatat aaacatccag ttgaacaacc
     4981 tcaattgaaa caattcgttg aatggttgaa agaattacgt aaagataacg tacttcaccc
     5041 tgactgggca gttatgaaag atgaaacttg ggaaggtcta ttggcttcta acaagggttc
     5101 attcactgtt gaccgtatga atatcattgg agataataac tttgataaat catttgattg
     5161 gcagccactt gtttatccag aaattaatgg aaaacgttat ttgcaaccga aaacaccgta
     5221 catttctgat tcaggttggg taatcaatgc caatgcacca aaagaagaaa ttgataaagc
     5281 gttagaattc tttaatttct tatacgctga tgaaaatcaa gaaaaacttg ctattggatt
     5341 tgaaggtaaa acatttacac gtgaaaaccc taatactcaa gcaggtatta aatggttgat
     5401 tcaaatttac ggtgaaaatg ctggaaatga taaagcagaa ctgctgttta aacatggtaa
     5461 ccaagcattt actcgcgttc aaactaaatt agatattgag gcacagccag gaacattccc
     5521 taaagttatg tatgatcaag tagataaaat taagaaagat ttaggtggtt ttagaccaga
     5581 tactccggtt ctttccttta caactgaaga attagatgtt ttaactaaat ctgaagcagg
     5641 attaaatact ttctttgatg aaaatattat taaattcatt gaaggacaaa gagatatgag
     5701 tgagtgggat tcatttatca atgaagctaa atctaaagac ttggataaag ttacaaaagt
     5761 atataatgat gcctacaaac gtgtcaaaga tagaatgaaa tagattaaat ggtagctctc
     5821 tgattattca gggagctact aagcctagaa agtgaatatt cgaaaatgta tgatgttgta
     5881 gttataggtg ctggtagttc aggtgctctt gcagcaattg cttctggtcg cctaggatta
     5941 aaaacctgtt taatcgaaaa agggagtcgt ataggtggcg taccgattaa tactctaatg
     6001 ggttcatttg caaatcttta cttcgatgat tctgggagag taaatgccag taagattgtt
     6061 ggtgagttaa ttgaacgtat tatagaaaaa ggtggaactg ttttttcttc gatggaagaa
     6121 ttgatgaatg taagcgactt ttatcaaatc acaatcccgt accaacctga agtctatgaa
     6181 tcagttctaa cagaaatgtt aaatgaatct aatgttgata ttcttctgaa tgtagaaatt
     6241 aacaatatag tttttgacaa caataagata catagtgtag aaatcatcag taatcaagaa
     6301 gtaaattatc ttgaatcaaa agtttttatt gatgctacag gtaatgctac gatagcttca
     6361 gcaagtggcg ctaatgtata tgaaaaaaat tcttcttatg gctgtttaat gagagtgggt
     6421 ggagttgaca tcactaagac tcttgaacat attgaaaaaa cgaagcagtg ggaattcgaa
     6481 gaaggttata atgaatggct agataatgta ttggctaacc gaaagtatag agctacaggc
     6541 gcagtattga gagatcccgt ttcttatgat catgctccta tgttaactaa agatgaccat
     6601 tttatgaatg aagaaaaatg gagttatatc aaggaaaggt gggagagatt cgggtttata
     6661 tatactttag aagtatcatt gtttagaaat gaattaagag aagcagttga agctggtgat
     6721 tttgagtttg aaatttatca tgatgatgaa tctggagtca ctatgaatgg cgacggtata
     6781 agctatggtt catggggtca aaatgtagca ttaattaatg ttgcaaaagc atttggattc
     6841 aatcccaaat atatggaaga tgaatcacat gctaatattc tttctagaaa atataattta
     6901 acatttttat cttttcttaa aaaatatgta ccaggttttg aaaattcttt tatccttgat
     6961 cagggaacta gagctactaa cagatcatgt aggcacattg ataattcatc tatgatggac
     7021 gaaattcttg attttccaat gtatacattt aagactatgt atagctatca aactcctaaa
     7081 gaaataacgt acaaatcaat tgtaggtgga aaattgaata atttgtttgt aataggtaaa
     7141 ggtgcttacc aatccgaaag ttttagatca caaattagtt gtatgttaat ggggatatca
     7201 tcagcagcag cggcaaaaac tattattgaa gataaaagca atactctaaa cattaataga
     7261 gatttgttta aatcgaa
//
LOCUS       DAVMAH010000074         6812 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVMAH010000074 DAVMAH010000000
VERSION     DAVMAH010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6812
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.074"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            4..1227
                     /locus_tag="VYO94_001888"
     CDS             4..1227
                     /locus_tag="VYO94_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011225314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase C family protein"
                     /protein_id="HEV1760469.1"
                     /translation="MLDNNIIDLLQRSCYTENRSYLSEYPSIIIYLSYRLANCDDNEH
                     SKLLYNRVNYYLHELLKSIKLNSRNNISMCYGFSGYVYALKLLPKRSKEYSKLLETLE
                     TILVSLTRDRLSEIKKSNKVKEEYIDVIQGVSSVGKYFLSKDKLTSNQELLLKGVLNY
                     LAGVINNKPTIYPEYMPNEKLKRKFPNGYINLGVAHGILGPLYVLALGFKKFNMPEYL
                     ISLKKGLSYYEKTFQTNKIGKIIGWNGRVSAEVESEKFEYNLSWCYGSLGMARVLYNI
                     SKIIDIPKLQELATDVFHSSIYYLNSSEILNNAICHGRSGIMLLFNLMYLDTGESQFK
                     AISDNLFKEIVNKATDSEYIFVERDIYFRGVNYDEVIEYIDFGLLNGVSGIVLALMAQ
                     RTGNASPLAEMFFMQ"
     gene            1256..2512
                     /locus_tag="VYO94_001889"
     CDS             1256..2512
                     /locus_tag="VYO94_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1760470.1"
                     /translation="MKKILNNKLYMKVLVSDLISNFGDTLYFIALMTYVTEIKSSNLA
                     ISIVNISETIPILFTIFFGIIADRTLNKVGMIIKTLWIRTILYLLVAVVMNFKESILV
                     VILASIVNLISDTLGQFENGLFYPISNRIVKKSDREETMAFRQTATSTMNIVNQSLGA
                     FLITFLSFFHLALINSLTFAISLLITLAIKSQINNFYIDKPPSTKVSKVDFKATFSDI
                     ISNLKLSLKHLFSLTNMKTVLLVIPILNGSLAIIIPLAVVNLSKSSALTIISSATTIS
                     VLGISTVSGGILGGTLILISKKFKNLSIENLLKMNLMTILLSFIAFYYQNIYFIVLTL
                     FLSSVFVSALNPKIGAIIFNNLDETKLATIFGGMVTYFQLGDVVSRLLFSTLVIYLSY
                     TYIAVIYMILVLIVAIYTFRRVQTTS"
     gene            2591..3268
                     /locus_tag="VYO94_001890"
     CDS             2591..3268
                     /locus_tag="VYO94_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1760471.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMAALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATNLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            3280..3945
                     /locus_tag="VYO94_001891"
     CDS             3280..3945
                     /locus_tag="VYO94_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1760472.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            4017..5243
                     /locus_tag="VYO94_001892"
     CDS             4017..5243
                     /locus_tag="VYO94_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1760473.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICMINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(5638..5715)
                     /locus_tag="VYO94_001893"
                     /pseudo
     CDS             complement(5638..5715)
                     /locus_tag="VYO94_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            5786..6442
                     /locus_tag="VYO94_001894"
     CDS             5786..6442
                     /locus_tag="VYO94_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV1760474.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWHNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGDLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLIVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            6432..6755
                     /locus_tag="VYO94_001895"
     CDS             6432..6755
                     /locus_tag="VYO94_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV1760475.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
BASE COUNT         1904 a         1127 c         1300 g         2481 t
ORIGIN      
        1 ctagtgttag acaataatat tattgattta ctacagcgct cgtgctatac ggaaaataga
       61 agttacttgt cggaataccc cagcataatc atatatttat catatagatt agctaattgc
      121 gatgataacg agcattctaa gttgctctac aatagagtaa actactattt acatgaactg
      181 ttaaagtcga ttaagttgaa cagtcgtaat aatatatcaa tgtgctatgg attttctggc
      241 tatgtatatg ccttgaaatt gttacctaag aggagtaaag aatatagtaa attgctagag
      301 acacttgaaa caattttagt atctttaact agagataggc taagtgaaat aaaaaaatcc
      361 aataaagtta aagaagaata tattgatgta atccaaggag tttctagtgt aggaaagtat
      421 tttcttagca aggataaatt gacttctaat caggaactat tattaaaagg agttttaaat
      481 tatttagcag gagtaataaa taataagcca actatttatc cggaatatat gccaaatgaa
      541 aaattaaaga gaaaattccc caatggctat atcaacctag gtgtagctca tggtatatta
      601 ggaccactat atgttttagc attagggttt aaaaaattca acatgccaga gtatttaatt
      661 tcgctaaaaa agggtttgag ttactatgaa aaaacttttc aaactaataa gattggcaag
      721 attattggct ggaatggtag agtaagtgct gaggtagaaa gtgagaaatt cgaatataat
      781 ttaagttggt gttatggtag tcttggaatg gcaagagtac tatataatat atctaaaata
      841 attgacatcc caaaattaca agagttagct actgatgtat tccactcatc tatttattac
      901 cttaatagta gtgaaatttt aaataacgca atttgtcatg gtcgctctgg gataatgctt
      961 ttgttcaact tgatgtattt agacacaggg gaatcacagt ttaaagctat ttctgataat
     1021 ttatttaagg aaatagtaaa taaagccact gattctgaat acatatttgt ggaacgtgat
     1081 atatatttta ggggtgtgaa ttatgatgaa gtgatagagt atattgattt tggcttgtta
     1141 aatggggttt ctgggatagt tcttgcacta atggcgcaga ggacaggaaa tgcttctcct
     1201 ttggctgaaa tgttttttat gcagtgaggg tttaaggtag atatagggat aacatatgaa
     1261 aaaaatttta aataataagc tatatatgaa agtcttggtt tcagatctga tatcaaactt
     1321 tggagataca ctatatttta tagctctcat gacttatgtg acggagatta agagtagcaa
     1381 tttggctatc tcaatcgtaa atatatcgga gactatacct atattgttca caatattttt
     1441 tggtatcatt gcagatagga cacttaataa agtgggaatg attatcaaaa cgttatggat
     1501 acggacaatt ttatatttat tagtggctgt tgtcatgaat tttaaggaat ccattttagt
     1561 agtaatactt gctagtatag ttaatcttat ttcagataca ttggggcaat ttgaaaatgg
     1621 tcttttctat ccaatttcta atcgaatagt gaaaaaatca gatagggaag aaaccatggc
     1681 gtttaggcaa acagcaactt ctaccatgaa cattgtaaat cagtcgttag gggcattttt
     1741 aatcactttt cttagtttct ttcacttagc tcttataaat tctctaacat tcgctattag
     1801 tttactaata acattagcta tcaaaagcca aattaacaat ttttatatag acaagccccc
     1861 atccactaag gtttcaaaag ttgattttaa agctacgttt tctgatatta tttcaaactt
     1921 aaaactttcg cttaaacatc tatttagtct cactaatatg aagactgtat tacttgttat
     1981 tccaattctt aatgggagct tagccattat cataccacta gctgtagtga atctttctaa
     2041 aagttctgct cttacaatta ttagttctgc aacaacaatt tcagttttgg gaattagtac
     2101 tgtttctgga gggattttag gtggaacttt gattctaatt agtaaaaaat ttaaaaatct
     2161 ttccatagag aacttattga aaatgaattt aatgactatt ttattatcat ttattgcgtt
     2221 ttattaccaa aatatttatt ttatagtatt aacattattt ctttcgagtg tatttgtcag
     2281 tgcattaaat cctaaaatag gagctatcat atttaataat cttgatgaaa cgaaactagc
     2341 tacaatattt ggaggaatgg ttacttactt ccagttggga gatgtcgtat caagattatt
     2401 gttttctaca ttggtaatct atttatctta tacttatata gcagtgatat atatgatatt
     2461 agttttaata gtggctatct atacttttag aagagtacag actacaagct gagagaattt
     2521 tgaaatttta actttattcc tccagtcctt gcaattagat ataaaatagg ctcttatagg
     2581 agataatagg atgaagaaaa tgaaagaagt gaaatttcac ctagcaactg gcttgttgat
     2641 tttgacttat tacctcattt ttaatgtcac atcagactta gattttatgg ctgctttgtc
     2701 tgataatatg tactatgtgt tccaagtttt attggtactt attctgggaa ctatagctac
     2761 aattgctttt gtcaaaagtg aacattggaa agagtgtggt cgtttccagt ttcgttggtc
     2821 ttacctgggt gttttccttc tttctttttt cttattgttc gtgtgggcaa atctaacaac
     2881 ctatatcttt cctcgtaccc agaatggaag tacagtcgta gaagtagcca ccaatttaac
     2941 aggaattagc tattttgtta cgcgaatact ttatactagt attatcgcac ctgtatcaga
     3001 agaggttgtt tgtcgtggtc ttttgatgac aagtttatct aaagttaaga gatactatct
     3061 tgatgttctt gtttccgctg ccatatttgg cgctatgcat gttttgcagt atggttggat
     3121 aacgacagat ttcataaagt attttggaat gggcttgata ttttgtatga tgtttcgcta
     3181 cacccgatcc atctattggg ctatagctct gcatgcttca tggaatagtt tcttactcat
     3241 tgttacttta ttggtatttg gatattagaa aggtgatata tgaaaaagat aatctcacac
     3301 cgctacttta ttatagtttt tctactagtt attgctgacc agaagttcag tgttttagtt
     3361 ttacgcagcg accttgttac tgggctatct gactttgcct attatctgtc ggatatgatg
     3421 ttgaattttc ttgtggtttt atttgctctt attgctatga tttggtcggg gaaatggcag
     3481 aaaatcaata gtagaaagtt taaaggatcc tatcttttct attccttcct agctctgctt
     3541 gcttttgttg tttggaattt cgttaccttt tttcttttcc cacctactcg aaatgaaatt
     3601 tcttatcaac atgctgctcc gacttttaca ggggctacag catttttgat gtattttttc
     3661 tatcctgtga ttgcaggtcc catttttgaa gagataatcc atcggggatt ggtgatgaca
     3721 gctctggaaa aaggaaagaa atgggggcta gatgtacttg gctctgctat tttatttggg
     3781 gtctcgcaca ttagtaatca cggttgggtc ttgacagact ttgtcttcta tatgggtgga
     3841 ggtcttatat ttgcagtctt atttagaatg acaaagtcaa tttattggcc tattggactg
     3901 catatagtct acaatggtat tggtcagctt ttgatgttac tgtaattttg gttgttagta
     3961 gtatcgcggt ctattcttgg ggaaagattc ccatttgaac ttaagaagga gttgtaatga
     4021 aagtatttct tcaaaataga gattttaggc aattaactat caaccagtgg atttcaacgc
     4081 ttggggatac gattttttat ctggccttcc tgaattatgt ggcagatgcg tcttttgccc
     4141 ctttggcgat tttacttatc acgatttcag aaacccttcc ccaagttcta caaatctttc
     4201 tgggagtttt ggcggatttt caacatcatc gtgtcttgaa atacacagtc attagtttta
     4261 caaaattttt gctttactct atagtgtccc tatcgctttc agggcagtct ttttccttgt
     4321 tgctagtaac ctttatttgt atgattaacc tcttgtctga cacattgagt tatttttcag
     4381 gcgccatgct cactccgatt ttcattagaa ttattgggca agatcatctg gcagaagcta
     4441 ttggatttaa acagtcaact gttagtttag tgaaaacaat cagtaatatc ctaggaggag
     4501 tcttactagg tattctatcc atccagttta tttccttact gaacgctctt acctttttaa
     4561 tcgcattttt aggtatcctc ttcataaaaa ctgacctctt gaaagtagaa aaaacgatta
     4621 gctatcaaga aggactctct gtaaaatcct tttgccagca tttgctccaa tcatcgaaat
     4681 tgatatggaa tatgaataag gtgctcttgg ttttgtttat tatctctact agtcaagcag
     4741 tgataaatgt tacagttcct gtctctactc tatttttgag gaatcaaccc tttttgaatt
     4801 tacaaacagg tcaatctctt gccttgctat ccacttttga actgtcagcc ctgattgtcg
     4861 gaagccttgt aagtggctat ctgcaacata ccatttccat aaaaacagct ctctatgcct
     4921 cacttgtcat ccagttgctt cttctagtag gatttgccac agttcgtttt gactggattc
     4981 tcatctttag taccttggat gcctttttcg caggtgttct ctctcctaga ttgcaagaac
     5041 tcgtctttaa acaaatacct gaggagtcaa tgggagcagt tcaatcttct atcagtgcca
     5101 ttacggttgt tttacctagc ttatttacaa tatctttggt aaccattgct actagctttg
     5161 gaactctggc agttagcttt gttttattgc tatttcttct agttgccttt gttatgcttc
     5221 tgaatattcg tgaaagtatt tagtggagaa tttctataat atatgtttga gactggattg
     5281 ccagtctttt tatgatggtc aaaatcaaca gactttttct cttttctgaa tgtgttatag
     5341 tagactgaat ctaaaatagt acgaaacaat tgctaaaaca tttatagaaa ttaattttac
     5401 tttcccaatc gatttgttct catcttattt caatctgcta tataatagtc catgctgtgg
     5461 ctggattctt ttcagcctac ttatactctt cgaaactctc ttcaaaccac gtcagcttca
     5521 ccttgccgta gtacggttac tgacttcgtc agttctatcc acaacctcaa aacggtgttt
     5581 tgagctgact tcgtcagttc tatccacaat ctcaaaacgg tgttttgagc tgacttcgtc
     5641 agttctatcc acaacctcaa aacggtgttt tgagcaacct gcggctagtt tcctagtttg
     5701 ctctttgatt ttcattgagt attattaaga caatatgagg agaaagatga aagaaaaagg
     5761 attttaggag ggggcgcagg cagccatgcc aacggctctt ggctatgtca gtatcggcct
     5821 ggcctgtgga attatcggtg cgccctatgt gacacctgtt gagatgggct tgatgagtct
     5881 ctttgtttat gctgggagtg cccagtttgc catgttggca ctgattgtgg ttcaagctcc
     5941 tgtggcagct attgctatga cggtttttct aatcaatttg cgtctctttt tgttgagctt
     6001 acacgcatcg acttatttcc gtcataccag tctttggcac aatatcggta tgtctagtat
     6061 cttgacagat gagacctatg gcgttttgat gggcgaatta gcccatacag ataaggtcaa
     6121 tccgatgtgg atgcacggga acaatctcaa cagctatgtg gcttggtttg tgggaacagt
     6181 ggtcggaacg gctctaggtg acctgttgcc aaatccagaa atctttggct tggattttgc
     6241 cctggttggg atgtttattg gtatttttgc ttcgcaattt cagattatgc aaagacggat
     6301 tcctgtccgc aatctgctca ttatcctagc agttgttgcg gtgtccttct ttttgctctt
     6361 gatagtggtg tctcagtcac tagctgttct gtttgcgacg ctacttggtt gtagcatggg
     6421 ggtggtttta gatggtcagt aagtatcttt tattagcagt tattttctct ggcttggtga
     6481 cttggattct ccgtatgatt cccttcatct tagtcaagta taagggcttg cctgcaatcg
     6541 ttgagcgttt tttgaagttc ttgcccgttt ccattatctt tgccttgatt ctttcaagcg
     6601 tagtgacagg taaggttggg agccttcctc aaattaaatg gctagacttc ttagccgtct
     6661 ttccaacagc ttgggtagcc tttcgctacc gcaatctagt cggaacagtt ctctttggag
     6721 tggtcttgat tgccatcttg cgtttggtct tttaaatcag ccataaagaa aacctatcac
     6781 agatatatat atcatataat ggtgtaaatg at
//
LOCUS       DAVMAH010000075         6502 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVMAH010000075 DAVMAH010000000
VERSION     DAVMAH010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6502
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.075"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            51..245
                     /locus_tag="VYO94_001896"
     CDS             51..245
                     /locus_tag="VYO94_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1760476.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(611..1921)
                     /locus_tag="VYO94_001897"
     CDS             complement(611..1921)
                     /locus_tag="VYO94_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV1760477.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEDQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2157..3029
                     /locus_tag="VYO94_001898"
     CDS             2157..3029
                     /locus_tag="VYO94_001898"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV1760478.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3160..4006
                     /locus_tag="VYO94_001899"
                     /pseudo
     CDS             3160..4006
                     /locus_tag="VYO94_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            4209..5068
                     /locus_tag="VYO94_001900"
                     /pseudo
     CDS             4209..5068
                     /locus_tag="VYO94_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857688.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            5245..6252
                     /gene="gap"
                     /locus_tag="VYO94_001901"
     CDS             5245..6252
                     /gene="gap"
                     /locus_tag="VYO94_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV1760479.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHNVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(6342..>6502)
                     /locus_tag="VYO94_001902"
     CDS             complement(6342..>6502)
                     /locus_tag="VYO94_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1760480.1"
                     /translation="PYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKER
                     TKFVLSRA"
BASE COUNT         2033 a         1112 c         1406 g         1951 t
ORIGIN      
        1 aatcatttaa aaaaatttta tttttttatt tttcattacg aataatatag atgaagggga
       61 aagagtatga aaacagaact gtttcttttg ctattagttc aaaaggagaa aaaatgaaag
      121 tagaaaatat ttcgtatagg gtggatcatc gtatattgtt tgataatatt tcttttgata
      181 cttcgagttc aggcgtgaca ttaattactg gtaaaaatgg tacaggaaag tcaactttac
      241 tatagtagat tgaaactaga atagtacaca tctgcttcta aaatattgtt agaaatcgat
      301 ttgactatcc tgatctattt ctcctgttct tatttcattt cactacatct caaattgagt
      361 atgacgaagt gcgctcccat gtcctgggaa cgcactttct tcatattttt catattcttg
      421 aatccatcga taaagactat tgggatgagt ttttaaagtt gaactaatca tttttacagg
      481 atgaggttta cagcagagag tttgaaggct ttatcaaagg tttttcttgg cataatgact
      541 tttcctcgtt tccgcttaat tttgtgtcta ctttatgata ccaagtccac ccttaagtta
      601 gataataaat ctaacttaag gaagctagaa ggatgagaat ccaggtggtc aagagtccca
      661 aacttaagct gatggggaca cccagaataa tttgcttttt gaaggcaagg ccacgttcct
      721 ctatattggg aagtgagagt tgaatgagag aaccagctga tgaaaagggt gagatattag
      781 tagatagagc gccaataacg gtggctgttg tgagtaagtg aatatcaatc tgaggatttt
      841 gagcactgat gatagcaatg atgggaaaga gggctggagc tacaacggat agggtggaac
      901 taaagagtga catcactccg gctatcacac aaaagaacag aggtaaccag aaatgaggaa
      961 tggatgttgt catgaggtgc cctatcagtg tgactaaacc tgacttgacc gctagagaca
     1021 ttagtaagct catgccgcag agcatgataa ttgtagccca gggaacttta gccaaaatgg
     1081 cttcttgctt ccctaatttg agccttaagg cgaggcagac cataagtatt gagacaaagc
     1141 caatatcaaa tgttttttga taagtagcta tccaggcgat gtttgggaaa atgagatgca
     1201 acaagggaaa aagccaaacc aaaaccatgc tgctgatcat gagcaaggtg gtttgtcttt
     1261 gaaccttgct gaggagtggt ggttggtcaa tagtcaagga tgagtttgtt cttcccttac
     1321 tatagtgact gtaacaggat aataaaagca agacgatgag tgggtagata atgctgacga
     1381 taaagatatg attgccaagt gaaaaagctt gatcttccca tcccatttgc ttaaacaggc
     1441 cttgaaagac aatgcctgag ctactggtta tcaaattagc ccctcctgaa gctccccaat
     1501 tgacggcttg agctccaatc aaagggtgtt tgtccgcttt ttgacagagg gtaatcgcta
     1561 gaggacagca aacggccata gtagtgaaaa atccagcacc taaagcagac aaaagggttg
     1621 ccatcaggta taaaatcatg tagagggcgt tagggtaggt gcgtgtgcgg tagagaatgt
     1681 gttgagccaa aacatcaaga gtaccgttag ttattgcaaa gttataaaag agagagacgc
     1741 taaaaatggt aaaaaagagt gaggttggcc aaaaatgaag aagttctttg gggcttaatc
     1801 ccatgagagt ggttgcgatg aggtaagaaa aagcaatagc cagcaggcca atattgattt
     1861 tggtgcggta accaattcca atggctagag caatggcgct aatcattatt aaatgaatca
     1921 ttgaattgtc ctttcagtta gaatatggaa ataggttggc aattttggcg ctcaaaagac
     1981 cacctgtttc ctattggtac ttgactatta tacacaaaaa aatacaattg tcttgacaat
     2041 tgtattgaca cttgttagaa ttaaaaatga ggtattcagg cttgtgattt cctatggaag
     2101 ttaatagtga ttgcctctaa tgcttacaag tgatattaaa aatagaggac ctagtgatgt
     2161 caatcatttc aactgattta accccttttc aaatagatga tacattgaaa gcagccttgc
     2221 gagaagatgt tcattccgaa gattacagta ccaatgccat ttttgatcat catggccaag
     2281 ccaaggtgtc gctttttgcc aaggaagctg gtgttttagc ggggctaacc gtttttcaaa
     2341 gggtttttac cctatttgat gccgaggtga ccttccagaa tcctcatcaa tttaaggatg
     2401 gggatcgttt gactagtggc gatttggttt tagaaatcat aggctcggtg agaagtctct
     2461 taacatgtga acgcgttgcc ttgaattttt tacaacattt atcagggatt gcttcgatga
     2521 cagctgctta tgtagaagcc ttaggcgatg attgcattaa ggtatttgat actcgaaaaa
     2581 ctactcctaa tttacgtctt tttgagaaat atgccgtgag agttggcggt ggctataatc
     2641 atcgctttaa tttatcagat gctatcctgc taaaagacaa tcacattgcg gcagtaggta
     2701 gtgttcaaaa ggcaattgct caagcgcgtg cctatgcccc ttttgtgaaa atggtcgagg
     2761 tggaagtgga aagccttgct gctgccgaag aagctgcggc ggcgggtgct gatattatca
     2821 tgttggataa tatgtcattg gaacagattg aacaggccat taccctaatt gcaggacgtt
     2881 ctcggattga atgttctgga aatattgata tgaccactat tagccgtttt cgtggtttag
     2941 cgattgatta cgtctccagt ggtagtttaa cccatagtgc taagagtctt gatttttcca
     3001 tgaaggggtt aacctacctt gatgtctaag ttgtaaaata aactaacttt ttaaaggatg
     3061 tctttcctct agaacgagtt ttatgtcaga tagtttaaac gcctcttcaa atatagtaaa
     3121 atgaaccaaa aatagtacac aatgtggtat aatcttctta tggcatattc aatagatttt
     3181 cgtaaaaaag ttctctctta ttgtgagcga acaggtagta taacagaagc atcacacgtt
     3241 ttccaaatct cacgtaatac catttatggc tggttaaagc taaaagagaa aacaggagag
     3301 ctaaaccacc aagtaaaagg aacaaaacca agaaaagttg atagagatag acttaaaaac
     3361 tatcttactg acaatccaga tgcttatttg actgaaatag cttctgactt tggctgtcat
     3421 ccaactacca tccactatac gctcaaagct atgggctaca ctcgaaaaaa aagaaccaca
     3481 cctactatga acaagaccca gaaaaagtag ccttatttct taagaattta atagtttaaa
     3541 gcacctagca cctgtttata ttgatgaaac aggattcgat acttattttt atcgagaata
     3601 tggtcgctca ttaaaaggtc agttaagaag aggcaaagta tctggaagaa gatatcagag
     3661 gatttctttg gttgcaggtc taacaaatgg tgagttaatc gctccaatga cttacgaaga
     3721 gatgatgacg agcgactttt ttgaagcatg gtttcagaag tttctcttac caacattaac
     3781 cacaccatcg gttattatta tggataatgc aagattccat agaatgggta agttagaact
     3841 cttgtgtgaa gagtttgggc ataaactttt acctcttcct ccctactcac ctgagtacaa
     3901 tcctattgag aaaacatggg ctcatatcaa aaagcacctc aaaaaggtat taccaagttg
     3961 caataccttt tatgaggctc ttttgtcttg ttcttgtttc aattgactat atatcacgga
     4021 tacagttggg aaagaagcta ttaaatattt ggagagtcct tttgggatga acatgtcaaa
     4081 tattactata gatgggcaag aaaagatggg caagaaaagg atctgagtca aacgatgctt
     4141 cttatgctca agtagtgagt ctttatgagg atacaagtat ctctgttagt aataatgaga
     4201 cggacaaagt gttggctgga tccctctata ctgatacaaa tgaacaggga ttaacgattc
     4261 caagcagttt actaaaaaat tggaatgaac agacaggaaa aaatttgaca gctaatgatc
     4321 ttattggcaa atcagtctca gccagcattg tagaaagtgc tgccgaagct agtaagattg
     4381 ctcaatttca aacgaagatt gtacgtgtaa tcaatgatga agatgacatg gaggacagca
     4441 acagtttcat gctgtcttat caaatggaaa cgattttgaa agaggctgga tttacgaaag
     4501 ctgtatctta ttttatcttg gaactcaaag atccatcaca gacaaaagta gtaacagaag
     4561 agttacagaa aaataagaag tatactgtgc tttctcaaca gagagttctt gatattgtga
     4621 ttacctttat tcgtgttatt cagggattat tgattgtgct ttcatcacaa gctattgtgg
     4681 tagcagcggt tatgattggt atcattattt acatcaatat catgcagcgt tccaaggaaa
     4741 taggtgtcat gaaggcagtt ggttatcaga atcgtgatgt caaaggaatt tttatttacg
     4801 aggctatctg gattgtaggc atcgccttgc tgctggcatt tttggttgca caaggggtgg
     4861 gaagtttggc gaatgcgatt gtaagtcact tttacccatc catcactaaa gtttttgaat
     4921 taaatctttt atctgtttta ggaactctag ttttcgctct attacttggt tatgtctcag
     4981 cctacttcta cttggttatg tctcagccta cttcccggcg cgtaagatta gtaaaatgga
     5041 tcctgtagaa tcgttacgct atgaataata agggattcct tgatttacag tcttaaaaag
     5101 aaactcacac agaaaaacaa tggccatact tgcaattcaa ctcaaatagt tgtataatag
     5161 gtttgttgaa aggtgatttg tagtgattca agttactctt ttcacaataa aaatttcatg
     5221 attttcataa ggaggaaatc actaatggta gttaaagttg gtattaacgg tttcggacgt
     5281 atcggtcgtc ttgctttccg tcgtatccaa aacgtagaag gtgttgaagt tacacgcatc
     5341 aacgacctta cagatccagt tatgcttgca cacttgttga aatacgacac aactcaaggt
     5401 cgtttcgacg gtactgttga agttaaagaa ggtggatttg aagttaacgg taaattcatc
     5461 aaagtttctg ctgaacgtga tccagaacaa atcgactggg ctactgacgg tgtagaaatc
     5521 gttcttgaag ctactggttt ctttgctaag aaagaagcag ctgaaaaaca ccttaaaggt
     5581 ggagctaaaa aagttgttat cactgctcct ggtggaaacg acgttaaaac agttgtattc
     5641 aacactaacc acaacgttct tgacggtact gaaacagtta tctcaggtgc ttcatgtact
     5701 acaaactgct tggctccaat ggctaaagct cttcaagaca actttggtgt tgttgaagga
     5761 ttgatgacta ctatccacgc ttacactggt gaccaaatga tccttgacgg accacaccgt
     5821 ggtggtgacc ttcgccgtgc tcgcgctggt gctgcaaaca tcgttcctaa ctcaactggt
     5881 gctgcaaaag ctatcggtct tgtaattcca gaattgaatg gtaaacttga cggatctgca
     5941 caacgcgttc caactccaac tggatcagtt actgaattgg tagcagttct tgaaaagaac
     6001 gttactgttg atgaagtgaa cgcagctatg aaagcagctt caaacgaatc atacggttac
     6061 acagaagatc caatcgtatc ttcagatatc gtaggtatgt cttacggttc attgtttgac
     6121 gcaactcaaa ctaaagttct tgacgttgac ggtaaacaat tggttaaagt tgtatcatgg
     6181 tacgacaacg aaatgtcata cactgcacaa cttgttcgta ctcttgaata cttcgcaaag
     6241 attgctaaat aattcttgag ttgatagaaa gcaaggcttt gtggtcttgc tttttatatg
     6301 gaaaaatggg ctctttgtca actgtagtgg gttgaagtca gctaagctcg agaaaggaca
     6361 aattttgtcc tttctttttt gatattcaga gcgataaaaa tccgtttttt gaagttttca
     6421 aagttccgaa aaccaaaggc attgcgcttg ataagtttga tgagattatt ggtcgcttcc
     6481 aatttggcgt tggaataagg ta
//
LOCUS       DAVMAH010000076         5476 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVMAH010000076 DAVMAH010000000
VERSION     DAVMAH010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.077"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(450..1310)
                     /locus_tag="VYO94_001903"
     CDS             complement(450..1310)
                     /locus_tag="VYO94_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV1760481.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1326..2603)
                     /locus_tag="VYO94_001904"
     CDS             complement(1326..2603)
                     /locus_tag="VYO94_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1760482.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2596..3147)
                     /locus_tag="VYO94_001905"
     CDS             complement(2596..3147)
                     /locus_tag="VYO94_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760483.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3163..4422)
                     /locus_tag="VYO94_001906"
     CDS             complement(3163..4422)
                     /locus_tag="VYO94_001906"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1760484.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT         1686 a         1247 c          883 g         1660 t
ORIGIN      
        1 tggtacgctg aacaccaaca agacgcttaa atcgtgcatc agttagttgt ttacttgctt
       61 catcattcat agaactacta taccatattt tgtttcgcag gaagtataat ataaaaaaat
      121 aaatttaaga ttggcaatac gaacgttaaa cagaattcca tttctctttt tagaatcaaa
      181 acgacaatat tgtggaatct ctacaggaac aatagactgc gacactaaaa tatcctccct
      241 tagttttact ttactaatag tatataggag gagagccctg aatcctagac cctttgttat
      301 gatgcgctta caaacagagt tggaaaaaat cttaaaagca gaaaaacgca tgatatcagc
      361 ccctaacact tgatacaatg cgttttatta tgaaaagatc tactggattt tttatcaaaa
      421 taaacttcca gtagtctttt cactttttat taataagttc cttcttcacc ttggctagtc
      481 aagataacag gtccatcttt cgtaatgaca aattggtgtt catactgaca tgacaatcca
      541 ccgtcaatgg tcttatgcgc ccaaccagtt ttcatatctg tatcaatttc ccaatcgcct
      601 gtattgatca ttggttcaat ggttaagacc attccttcac gaagacggag tccacgacct
      661 gcaataccat agttaggaac cattggttct tcgtgcatag ttgggccaac accatgacca
      721 accaaatcac gcactacacc gtaaccacga ctttcagcgt attcttgaat agccgcaccg
      781 atatcaccga tacgatttcc aacaacagct tgctcaatac ccttgtacat agcttctttg
      841 gttacatcca tcaagttttt gacttcttcg gacggtgtac caacagcata agcccaacat
      901 gagtctgcta aaccaccaga atagctctga gtgtattttt tcatttgttc aacattgttg
      961 aagtttaatt ttgagacatt taggtcagat ttagcaatgg gacctcccaa aaccatatca
     1021 actttgagca aatcaccatc tttcaagata taatgacgag ggaaagcgtg agccacttca
     1081 tcgttaagag agcaacaggt agcataagga tagtccatca tggcaccgtc aaccccaatc
     1141 tgaagtggaa ggaaattttc ttctttacaa cgacggcgga catattcttc aacttcccac
     1201 atatctacgc ctggcttaat caaatcacgt aagcctatat gaatacttgc tagaaaatca
     1261 ccagccttgt ccatagcttc gatttcacga gctgatttta atgttatcat cttttctcct
     1321 agtttctaat taattttaac agtcacattt gcttttgaaa caatctggtg accatgataa
     1381 atatcgtaat caattatagc tgaccgtctc gtatgatgaa taatccgtgc ctgaatgcgc
     1441 aatatatcat ctatctgaac agcctgcaaa aagtagatca gcatctgctc gataatgaga
     1501 ttgcgaccac tattaacaac taaatcttgg gtcatgtggg tcagaatttc tgccaataca
     1561 ccattagcca aaactccatt tttttctagc ataaagggtt ccactgtaat gactacttca
     1621 tcatggtgat aagagagctt ttgtccaatc tgctcagaaa aagttggtag agccgaaact
     1681 tgggaacggc tcatcttctc catgacatct cgtcgcgtca caacgccaag caaagtttga
     1741 ttgcttcgaa caactggtac catttcaaag tcttctgcga tcatccgttg actcacattg
     1801 gcaatatttg tcgataatcc aaccaaaaat agactacgag acataacctt atcaattgtc
     1861 gtgcttggtg atttatcacc agcgtctctc atggttacaa cgccaacaac gacctgatgt
     1921 tgattgataa cagggaaacg gctgctacga ttcttacgaa ccaagtccaa ataatcttta
     1981 actgtatctg tctctctcag aaaaccatac tcatgactag ggcgataaag tttctcaact
     2041 gtcagaatat cagtcttgat ttggacattt gacaaggctt tattgatcat ggtcgcgacg
     2101 gtaaaggtat catgcttact tcttagaaca ggaatccctt tttgattggc cagtttaagc
     2161 acatcatcat gaacctgaaa tccccctgta accagaactg cattttcatt ttccaaggct
     2221 agcaactgaa tacgggttcg gtctccgaca atcaagagcc ccccatcatg aaggtaagac
     2281 aagatatttt gttcagtcat ggcaccaatt gaaaacttac taaattctct ctctaaacct
     2341 tcttgcccag ccagaacctc agaagaagtc acttctgcaa tttcagcaaa cgttaatctc
     2401 tctatagcaa ctttctggga tttaacacga attgttccac ttctaggacg ggtctccaca
     2461 attccacggt tttcagcttc tttaatagcc cgataggctg ttccatcact aactcctaga
     2521 tgattcgaaa tgctacgaac actgaccctt ttacctactg gtaattcctc caaatagctt
     2581 agaatttcct gatgcttact cattgaactc tccttttaca taccgaaatt caagataatc
     2641 ccgcattttt cttgtgtaac gatcacttcc cttaaactga cgaaacaaac taaatccaga
     2701 cttaagagca actctttggc tagcttcatt ttcaaggtgg gtaatgatag ataattgttt
     2761 taagccaaat tcctcaaaag aaagctgaca aatttttcta acaacctctg tcataaatcc
     2821 ttgcgaccaa gcatcttttc tcaaaaaata gccaagctca gcttcttttt tgatttcatc
     2881 taacttctca aatttaatag aaccaatcat ttgttgattt ttctggtcac aaattgccca
     2941 cactcccaaa ggggacttca taaagtaatt ggccagtgca tattgacttt cttccagact
     3001 tgcctgcgtt gggaaaataa attgaagatt ttctggattt gaagctatct cgcggaagtc
     3061 ctgactatca ctaaaaaaga aaggacgcaa atacaagcga tccgtttcaa aaaaagaaaa
     3121 cattgctaat ttggtccaaa tattcataaa cacctctacg gtttaatcct caacaagtct
     3181 aatatccgct cctaaattac gtaatttttc gataatatca gaataaccac gtaagataaa
     3241 ctcgatattg gtaatttcag ttttaccttc agccataagc ccagcaatga ctagtgcagc
     3301 cccagctctt aagtcggtcg ctttaacact ggccccacgt aaatcacgtc cacccgtgta
     3361 caaaatatga ccatttgttg tcgaaatatc cgcatccatc tttgctagtt caaaaacatg
     3421 atttacacgt ttttcgtaaa tcgtatcgac aattgtacca cgaccattcg ctcttagtaa
     3481 aagaggggta agcggttgtt gcaaatcagt tgcaaagcct gggtaaggag ctgtcttaat
     3541 attgattgct ttcaaattag actgttcctc gacaaaaatg ctgtcttcag atacagtcat
     3601 tctcactccc atttcttcca acttagcaat aaacccttcc aggtgttcgt aaagaacatt
     3661 atttatacga attcctttac caactgcagc agctaaagat atatatgttc cagcttcaat
     3721 gcggtctgga atcacctgat gacgtgtccc atgtaatctt tcaacaccat caataatgat
     3781 gatattagtt cctgccccac ggatatgggc acccatatta ttcaagagag tagctacatc
     3841 aataatctca ggttcacggg ctgcattttc aataatagta cgaccatttg ctttaaccgc
     3901 agcaatcatc gtattaatcg ttgctcccac actaaccgta tccatgtaaa tacttgcacc
     3961 atgaagtcct gtatctttag cagataactt catgttatct ccctcgtagc tagcagtggc
     4021 acccatagct tcaaacgcct taaggtgtaa gtcaatcgga cgaggaccaa gatcacatcc
     4081 tcccggtaga ccaactgtcg cttcaccaaa acggcctaag aggctcccat aaaaataata
     4141 agatgcacga agactgttaa ttttaccata aggcattgga atattttgaa cacctcttgg
     4201 atcaatctcc aagacatcgt cataacgctt aacagtagct cccatcaatt ccatgatttc
     4261 gacaagactg gctacatccg aaatatctgg aacacaatcc aaagtcacca catcatcagc
     4321 caatataata gctggaatta aggccacaac actattttta gcaccactaa tagtaatttc
     4381 accttgcagt ggtaatccac cattgataac aatttttctc attctaagtt ttcaatactc
     4441 tttcaagatt tctaataagg tcttcaaaat aaagtatatc ataaatttat ccttttttcc
     4501 atccttttca attttattgg ataaatcaga gttgacgagt tagtaactga attactaata
     4561 ctcaataaaa atcaaagatc aaactaggaa actagccgca ggttgctcaa aacactgttt
     4621 tgaggttgta gatggaactg acgtagtcag tatcctacac gtacggcaag gcgatattga
     4681 cgtgatttga agagattttc gaagagtata atctttctcg aatcgctatt gccccttttt
     4741 tatcccctga aaccgagtag gagctaagac tagatctctt atctaaatat cggaatacgg
     4801 ctgttcaact aaattttagc aagaacctct cccccttctc tcagttcaca gaagcgtttt
     4861 atacataccg tcctatattt catgaacaag acgttttcag gctagcatcc tatcagacaa
     4921 tctattttaa agataaccgt gactcaggat cacttctatc tgtcgttttc tctttatagt
     4981 gatagacctc acgggataag tcgtacatct ttcctcgtgt atacaagata tgaggacgtt
     5041 aaaaggttac agtgaaaata gaaaatctta gtacgaattc aattactctc gtgatttacg
     5101 catataggtt acgactacct ttttggactt tagagtttga ggccctctta tccgctatat
     5161 acgctttatt atcacgttcc tgttcgtaga gccacgattt cgctatccct tcttctgaca
     5221 attcttattt ccagcgtcag acttaaaacg gtctatcccc agaccatttt aatccgctac
     5281 ctcacgatag tcaggcttgg gaatcgctat ttgactcgcc gagaactttg acatcagata
     5341 tactataaca aattgaaata agaatcaaac aatttaattt tgaaattcaa atcaatttat
     5401 aacaatattt tagaagatat gctgtgctat tccagattca gtttgctata catgcctgtc
     5461 gtaccacaaa atccgg
//
LOCUS       DAVMAH010000077         5465 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVMAH010000077 DAVMAH010000000
VERSION     DAVMAH010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5465
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.078"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            653..1330
                     /locus_tag="VYO94_001907"
     CDS             653..1330
                     /locus_tag="VYO94_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV1760485.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            1317..2114
                     /locus_tag="VYO94_001908"
     CDS             1317..2114
                     /locus_tag="VYO94_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV1760486.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQVSTNPFRHI"
     gene            2131..3234
                     /locus_tag="VYO94_001909"
     CDS             2131..3234
                     /locus_tag="VYO94_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV1760487.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            3235..3315
                     /locus_tag="VYO94_001910"
                     /pseudo
     CDS             3235..3315
                     /locus_tag="VYO94_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            3535..4554
                     /gene="galE"
                     /locus_tag="VYO94_001911"
     CDS             3535..4554
                     /gene="galE"
                     /locus_tag="VYO94_001911"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1760488.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            4556..>5465
                     /locus_tag="VYO94_001912"
     CDS             4556..>5465
                     /locus_tag="VYO94_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1760489.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLI"
BASE COUNT         1575 a         1050 c         1271 g         1569 t
ORIGIN      
        1 cacccttgtg caggcacctt atctgataaa taatagtaat tccaaatatc accctgttgg
       61 aaatttttat cacattttaa acattctttc tctaataaat ccataacaaa ctcctaatta
      121 ttaaaatagg ctagagacac agcactagcc tattccgtaa gtaaagctac ttattttata
      181 taaaatataa ctagcgacct gtaattaaac aagtaaaaga acaatactta gggagacctg
      241 tgacaatgac atcttcctct ggaagtagtt ctaattcaaa caatgtttgt tccatgactg
      301 tatcctcctg ttatgataaa ttccagaaag catagagcaa attcgtggtt cgtctgacta
      361 aatttcttat ctgaacacca ccttcaaata caaattttag tcaaactttt attttttcta
      421 actttctaat tatattctac catgtgtttt tatatgtcaa gaattttctg aataaactgt
      481 ttatttttta ttttttgaca tttttgcaaa ttgtttaaaa tctttcaatt ggattcactt
      541 attactttag gacattgaaa cttctttcgc cagaggtgct tatattactg ggaagttgaa
      601 gattgaaatg tggtataata agaggtaata gagttttgga aagtgagaga agatgatttc
      661 aaagagatta gaattggtag cttcctttgt gtcacagggg gctattttac tagatgtggg
      721 aagtgaccat gcttatctgc ctatcgagtt ggttgagaga ggccaaatca aaagcgctat
      781 tgcaggtgag gtggtggaag gtccctatca gtctgcggtt aaaaatgttg aggctcacgg
      841 cctaaaggag aaaatccaag tccgtttagc caatggcttg gcagcttttg aagagactga
      901 ccaagtgtct gtcattacca ttgctggcat gggtggtcgt ttgattgcta ggattttaga
      961 agaaggtttg gggaagttag ctaatgtaga gcgtttgatc ctccagccca ataatcgtga
     1021 agacgacttg cgtatctggc tacaggatca tggattccag attgtagcag aaagcatctt
     1081 agaagaagct ggaaagtttt atgagatttt ggtggtggaa gcaggacaaa tgaagctatc
     1141 agccagtgat gttcgctttg gtcccttctt gtccaaagaa gtcagtccag tatttgtcca
     1201 aaaatggcaa aaagaagctg agaagctaga gttcgccctc ggacaaatcc cagaaaaaaa
     1261 tctggaagaa cgtcaagttc tagtagataa gattcaagct atcaaggagg tgctccatgt
     1321 tagcaagtga agtgatccaa gcttatgaag ccttttgccc tcaggaattt tctatggagg
     1381 gagacagccg tggtctgcaa attggcactt tagacaaggg tatccaaagg gtcatggttg
     1441 ccctcgatat tcgtgaagag acggtggcag aggccattga aaagggtgtg gacttgatta
     1501 tcgtcaagca cgcgcctatc tttcgtccta tcaaggactt gcttgccagc cgtccgcaaa
     1561 atcagattta catcgacctg attaagcatg atatcgcagt ttatgtcagc cataccaata
     1621 ttgatatcgt tgaaaatggg ctcaatgact ggttttgtca gatgctagga atcgaggaga
     1681 cgacttatct gcaggaaaca ggtccagaac gtggaattgg acgtattggg aatattcagc
     1741 ctcagacatt ttgggaattg gcccaacagg tcaagcaagt ctttgaccta gatagccttc
     1801 gaatggtgca ttatcaagag aatgatttgc agaagcctat ttcaagagta gcaatttgtg
     1861 gtggaagcgg gcagtctttc tataaggatg ctttggcaaa gggggcagat gtctatatca
     1921 ctggcgacat ctactaccat actgctcagg atatgctgtc tgatggcttg ttagcattgg
     1981 atccaggtca ctatatcgaa gtgctttttg tggaaaaaat cgcagcactc cttactcaat
     2041 ggaaagagaa aaaaggctgg gaactagaga ttttacctag tcaagtatcg accaatcctt
     2101 tccgtcatat ctagttagaa agtgaagaca atgaaaaaag ttgccattat tggagcagga
     2161 attgtgggag caacagctgc ctactacctc tcgagagaaa gtgacctaga ggtgaccgtt
     2221 tttgaccatg agcaaggtca agccaccaag gccgcagcag gaattatcag tccttggttt
     2281 tccaaacgcc gtaataaagc ctggtacaag atggcgcgct tgggggctga tttttatgtg
     2341 gatttattag ctgatttaga gaaatcagga caaaaaatcg acttttacca gcgttcggga
     2401 gtctttctct tgaaaaagga tgaatccaag ttggaagaac tttatcaact ggccctccag
     2461 cgcagagaag aatctccctt gatagggcaa ttagccattc tggaccaagc ttcagctaat
     2521 gaattattcc ctggtttgca gggatttgac cgcctgctct atgcttctgg tggagcgaga
     2581 gtagatggcc aactcttggt aactcgtctg ctagaagcca gtcatgtcaa gctggtcaaa
     2641 gaaaaagtga ctctgacact cttatcatca ggctaccaga ttggcgaaga ggtgtttgat
     2701 caggttattt tggcaacggg agcttggttg ggggacatgt tagagccttt aggttatgaa
     2761 gtggatgtcc gtcctcaaaa aggacaacta cgagattatc agcttgccca agacatggaa
     2821 gcttaccctg ttgtcatgcc agaaggggag tgggatttga ttccctttgc aggtgggaaa
     2881 ttatccttgg gcgctaccca tgaaaatgac atgggatttg atttgacggt agatgaaccc
     2941 ttgctccaac aaatggagga ggcggccttg cctcattacc cagttttagc tagagcgact
     3001 tcaagggctg agcgtgtggg aatccgtgcc tataccagtg atttctctcc cttctttggg
     3061 caggtgccag aattggcagg tgtctatgca gccagtggac taggttcatc aggcctcaca
     3121 actggtccta tcattggtta ccatctagcc caactgatcc aagacaagga gttgaccttg
     3181 gaccctctaa attacccaat tgaaaactat gtcaaacgag taaaaagcga ataatactca
     3241 atgaaaatca aagaacaaac taggaaacta gccgcggatt actcaaagca ctgctttgag
     3301 gttgtggata gaactgacga agtcagctca aaacactgtt ttgaggttgt agatagaact
     3361 gacgaagtca gtaaccatac ccatggcaag gcgacgttga cgtggtttga attggatttt
     3421 cgaagagtat aagcatttta ctgaaatttt atcaggtagt ttaggatggc aaatgacatt
     3481 ccctgtcaaa aatggtaaaa taagaaaaaa taatctgaga atcgaggaaa aaagatgcaa
     3541 gaaaagattt tggtaactgg tggtgccggt tttattggaa cccacactgt tattgaattg
     3601 atccaagcag gccatcaagt tgttgtggtg gataatcttg tcaatagcaa tcgtaagagt
     3661 ttagaagttg ttgaaagaat cacaggagtt gagattcctt tctatgaggc agatattcgt
     3721 gacacagata ccctcagaga tattttcaag caggaagaac cgactggtgt cattcacttt
     3781 gctggtttga aggctgttgg cgaatcaaca cgtatccctc ttgcctacta tgacaacaat
     3841 atcgctggaa ctgtcagcct tttgaaagca atggaagaaa acaactgtaa aaacatcatc
     3901 ttcagttctt ctgcgacagt ttacggggat ccgcacacag tgcccatctt ggaagatttc
     3961 ccactttcag tgaccaaccc atacggtcgt actaagctca tgctagagga aattttgact
     4021 gatatttaca aagcagactc agaatggaat gttgtcttgc ttcgttactt taacccaatc
     4081 ggagcccatg agagtggtga tttgggagaa aatccaaacg gtattccaaa caatctcttg
     4141 ccatatgtga ctcaagtagc cgttggaaaa ttagagcaag tgcaagtgtt tggagacgat
     4201 tacgatacgg aagatggaac aggtgttcgt gactatatcc acgttgtcga tttggctaag
     4261 ggtcacgttg cagctttgaa aaaaatccaa aaaggttcag gactaaacgt ttataacctt
     4321 ggaactggta aaggttactc agttcttgaa attatccaaa acatggaaaa agcggtggga
     4381 cgtcctattc cttaccgcat cgtagaacgt cgcccaggtg atatcgctgc ctgctactca
     4441 gacccagcaa aagctaaagc agaactcggt tgggaagcag aactcgacat cacccaaatg
     4501 tgtgaagacg catggcgttg gcagagcaag catccaaatg gatttgaaga ctaagatgat
     4561 gatttcaatc atcgtccctt gtttaaacga agaggaagta cttcctcttt tttatcaggc
     4621 tctggaagct ttacttccag atttggaaac agaaatcgag tatgtctttg tcgatgatgg
     4681 atcaagtgat gggaccttgg aactcttaaa ggcctatcgg gagcaaaatc cggcagtcca
     4741 ttatatttct ttctctcgaa attttggcaa agaagcagcc ctttatgcag gcttgcaata
     4801 tgcgacagga gatttggtgg tggtgatgga tgcagacctc caagatcctc ctagtatgtt
     4861 gtttgagatg aaaaatgtac tagacaaaaa tgtagacttg gactgcgttg ggacacggag
     4921 aactagtcgg gagggagaac ccttctttcg cagtttctgt gctgttctct tttatcgcct
     4981 catgcaaaaa atcagcccag tagctctgcc gtcgggtgtc cgtgattttc gtatgatgag
     5041 aaggtctgtg gtcgatgcca ttttaagctt gactgagtcc aatcgttttt ctaagggact
     5101 ctttgcctgg gtcggcttta aaacccacta tctggactat ccaaatgtcg aaaggcaggc
     5161 tggcaagacc agttggagtt ttaggcaact ctttttttac tccattgaag ggattgttaa
     5221 tttttcagat ttccctttga ctatagcctt tgtagctggt ctcctatctt gttttctttc
     5281 tctgctgatg accttttttg ttgtggttcg gaccctcatt ttgggcaatc cgacatctgg
     5341 ttggacctct ctgatggctg ttattctctt tcttggaggc attcaactct tgaccattgg
     5401 gattctcggc aagtatatca gtaagattta tttagagact aaaaaaagac cactttatct
     5461 tatca
//
LOCUS       DAVMAH010000078         5295 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVMAH010000078 DAVMAH010000000
VERSION     DAVMAH010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5295
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.079"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            208..930
                     /locus_tag="VYO94_001913"
     CDS             208..930
                     /locus_tag="VYO94_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1760490.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILLASIA"
     gene            1042..2376
                     /gene="pepC"
                     /locus_tag="VYO94_001914"
     CDS             1042..2376
                     /gene="pepC"
                     /locus_tag="VYO94_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV1760491.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(2432..3343)
                     /locus_tag="VYO94_001915"
     CDS             complement(2432..3343)
                     /locus_tag="VYO94_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1760492.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3367..4170)
                     /locus_tag="VYO94_001916"
     CDS             complement(3367..4170)
                     /locus_tag="VYO94_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV1760493.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4198..5187)
                     /gene="manX"
                     /locus_tag="VYO94_001917"
     CDS             complement(4198..5187)
                     /gene="manX"
                     /locus_tag="VYO94_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV1760494.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
BASE COUNT         1627 a         1072 c         1148 g         1448 t
ORIGIN      
        1 gaggaataag caaagtgcaa ttagaataaa tggaagaatc tttaaaaata aagctattac
       61 tacaaaaata agaaataaat agattaacca catatggatg tttcctttta aacgaagtat
      121 atttatacta taccataaaa ttgataatag ttcacctaat aaaatgttag ttatgtacaa
      181 caataatttc catgatataa tagttctatg agattagata aatttttagt tgcctgtgcg
      241 gtgggaagtc ggactgaggt caaaaacttg ctcaaggctg ggcgcgtgac tgtaaatggt
      301 aaaaaagaaa aatcagctaa attgcagatt gatgaaaaaa tagatgagat tcgctttgat
      361 gggcaagtgt tggagtatga agagtttgtc tactacatga tgaacaagcc caaaggagtt
      421 atctcagcga ctgaggatcc caagcacaga accgttctgg acttgttgga tgacttggcg
      481 cggagtaagg aagttttccc agtaggacgc ttggatattg acacgcatgg tcttttgctc
      541 ttgaccaatg atggtcagct ggctcatgtt cttctttcgc ccaagcgtca tgtggacaag
      601 acttatctgg cacaagtcaa gggaatcatg acccaagaag atgtggagac atttgctgag
      661 ggtattcctc tcaaagactt tacctgtcaa cccgctatac tggagcttgt atccatagat
      721 acagaaaaga atcaaagcca aatccgtgtg accattgcag aagggaagtt tcatcagatc
      781 aagcgtatgg tgggctactg tggcaaggaa gtggtggact tgcaacgatt gactatggga
      841 actttagtat tagatgagaa cctggaacga ggggaatggc gtcgcttgac caaggaagaa
      901 ttagaaattc tccttgctag tattgcttaa tttgatttat attcgaaaaa ggtgagggag
      961 aatgtcctta ccttttatgt tttttagttg cttcctttgt gaaaagagtt ataatagact
     1021 gtagaataaa aggaggaatc tatgaacgcg attcaagaat catttactga taaactattt
     1081 gccaactatg aagcaaatgt aaaataccaa gcgattgaaa atgctgccag ccacaacgga
     1141 atttttgcag ctctggaatg tcgccaaagc catgtagaca acacacctgt tttctcattg
     1201 gatttaacca aggacaaggt cactaaccag aaagcgtctg gtcgttgctg gatgtttgcg
     1261 gctctcaaca ccttccgcca caaactcatc tcgcaataca aattggagaa ctttgagttg
     1321 tcacaagccc acactttctt ctgggataag tatgagaaat caaactggtt cttggagcaa
     1381 gtcattgcga cttcagacca agaattgact agccgcaagg ttagcttctt actccaaaca
     1441 cctcaacaag atggcggtca atgggatatg gtcgtttccc tctttgaaaa atacggtgtc
     1501 gtgcctaagt cagtttatcc tgagtctgtt tcatctagca gcagtcgtga gctaaatgcg
     1561 atccttaata aattgcttcg tcaagatgct caaatcttgc gtgatttgct tgtttctggt
     1621 gcagatcaag cgactgttca agctaagaaa gaagacctct tgcaagaaat ctttaacttt
     1681 cttgctatgt cattaggact tccaccacgc aagtttgact ttgcttatcg cgataaagat
     1741 aacaactata aaagtgaaaa aggaatcaca ccacaagagt tttacaagaa atatgtcaat
     1801 cttcctttag aagactacgt ttctgttatc aatgctccaa ctgctgataa accttacgga
     1861 aaatcttaca cagttgagat gttggggaat gtggttggta gccgtgcagt tcgctacatc
     1921 aacgttccaa tggagcgctt gaaagaattg gcgattgccc aaatgcaagc aggtgagact
     1981 gtttggtttg gttctgatgt cggccagctc agcaaccgta aggctggcat ccttgcgaca
     2041 gatgtttatg actttgaatc aagcatggac attaaactta ctcaagacaa ggctggacgt
     2101 ttggactata gcgaaagctt gatgacccac gccatggtct tgacaggtgt tgacttggac
     2161 gaaaatggta aatcaaccaa gtggaaggtt gaaaactcat ggggagacaa ggtcggtaca
     2221 gatggttact ttgttgcctc agacgcttgg atggacgaat acacatacca aatcgttgtt
     2281 cgtaaggaat tgctgacagc agaagaacaa gctgcctatg gagcagaacc aatcgtactt
     2341 gcaccatggg atccaatggg agccttggct gaataaaagc atagaaaaaa ggaatcagat
     2401 tttagaacct ggttcctttt tagttgcttg attacatgat gtgaagaaca tgtgccacaa
     2461 tacccactgc gaagagggca aggataatag tgattggaga tacttttttc ttaagtaagt
     2521 acatgcaaag taaagtaagg agtagtcctg ataatccagg aatcaacata tccaagtttt
     2581 gttggaaagt agtaactttt tcaggagttt gagacaatcc ttgtcctact tgtgcgaatg
     2641 cttcttggat acctttagac ccttctggca atttatccca atggatataa gccttttcat
     2701 ctagttgaac tttagaaaca tcgaaagcaa atttaatatt tacccaacgt tgaacaagga
     2761 cagcaagaat gaacatccca aggatagaag ctcctttagt gatatcttga aggataccac
     2821 cagacatatc tttagtgatt tctgatccag ccttgtatcc aatctcttga acataccaca
     2881 agaatgacat acgaatcaag ttccatgcaa caaagaagag gagtggcccc aagatattgc
     2941 cagtaagggc aagtgaagca ccgagagatc caaggattgg gcgtactgta aaccagaata
     3001 ctgggtcacc gataccagca agaggtccca tcataccgat tttaacccct tggatagcag
     3061 cgtcatcgat ttccacaccg ttagcacgtt cttcttcaag cgcaagagta acccccatga
     3121 ctggagcagc tacgtatgga tgagtgttga agaactcaag gtgacgctca agagcagcga
     3181 tttgatcttc ttttttagta tagagttttt tgatagctgg aatgagtgta taagcccagc
     3241 ccaagttttg catccgttca aagttccaag acccttgtaa gaaggttgaa cgccaccaaa
     3301 cttttttacg atctgattta gttaattgaa gtttttcagt catgatgttt tcagtccttt
     3361 cttatcttag tagtcttcta ggatatcgcc gattgggtcg ttagaagttg cggctcctcc
     3421 gccaccattt ccaccagttt tagaaaggtg aaggtagata agagcgatag caacaccgat
     3481 agcaccgaat ccgattagag taatatctga cacagcagcg agaacgaaac caagagcgaa
     3541 gaatggccat acttcacgag ttgccatcat gttgataacc atggcgtaac caacggcaac
     3601 gaccatacca ccaccgatag ccataccatc tttgagccag tctggcatgg cactaaggat
     3661 actttgtaca gtttcagttg gtaccataag gagaagagct gcaggaagcg cgatacgaag
     3721 tccttggaag agtagcgcaa tgaaatgcgc acgctccaca gcgccgaagt cacctttttt
     3781 agcggcagca tctgcagtat gaaccaaacc aactgaaatt gtacgaacaa tcattgtcaa
     3841 gaaaagtcca gctacggcaa gagggatagc aaccgcttgg gcaacaccga taccagtctt
     3901 ggtaaagtca ccaccaagaa ccatgataat ggcagcagcg acagaagcaa gtgcagcatc
     3961 aggagcgata gcagcaccga tatttgacca accaagggca atcatttgaa gcgatccacc
     4021 gaggataatc cctgcttcca agtgacctgt tacaagccca ataagggtac aggctacaag
     4081 tggttggtga aattggaact ggtcgaggat gccttcaaga cctgcaaaga aggctacaac
     4141 gactactaaa accatagaaa taatagacat gtttaaaatc ctttcataaa taatggctta
     4201 tttgacattg gctttgttaa tcaagtcaaa caaatctttt ttagaatcat ttggtacttt
     4261 acggacatca aattcaacac ccaagtcacg cattttttca aatgtagcaa catcttcttt
     4321 gtccatagac aaaacggtat tgaccaatgt tttacctgtt gagtgagcca tagaaccaac
     4381 gttaagagtc ttgattggca cgccgccttc gatggcacga agggcatctt gaggtgtttc
     4441 aaacaagata agggcatgtg tttctccaaa acgtgggtct tttgaaatct caatcagttt
     4501 ttgaattgga accacgttag ccttgacatt acctggagct gcttgtttaa tcaattcttt
     4561 acgaaggtcg tctttagcca cgttatctga agcaacgatg atacgatttg cttttgaatc
     4621 tggagtccaa gcagttgcaa cctgaccgtg aagtagacgt gtgtcaagac gggcaagatt
     4681 gattttcaat ttaccgtctc cgataacagt tccttctggg atagcagttt gggcaactgg
     4741 agcagctgca gcgcttgcaa cttcttcaac tggatttagc tcttctggaa gagctttgat
     4801 gccatctttg gcttctttaa tgatattagc agcgactttt tctacacctg cagcagcgtc
     4861 catgaggcgc tctgtgtagg cttgaatcaa catcggtaag ttaagtcctg tgatgatggc
     4921 aaacttacgc tcaggatttt ctcccatcac gcgactagct tggttaaatg gagaaccact
     4981 ccaaaggtca gccaaaacta gaacctcatc ttctgcgtca aatgcagcaa cagcgttatt
     5041 aaacttagcg tatagatcat caggaccttc atttggcata aaggtcacaa cttgaacctt
     5101 ttcttgttca ccaaagatca tagatcctga ctgatgaata cccgcagcaa attcgccgtg
     5161 gctcgcaata atgattccga tactcattat tgtcattcct ccttttttgt tttagttttc
     5221 atttaagaaa actttaagac tgtttaagta taaaccgttt tcataaaaaa agcaactatt
     5281 tatcataaaa aatta
//
LOCUS       DAVMAH010000079         4899 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVMAH010000079 DAVMAH010000000
VERSION     DAVMAH010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4899
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.080"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            88..669
                     /locus_tag="VYO94_001918"
                     /pseudo
     CDS             88..669
                     /locus_tag="VYO94_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164186.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            826..1194
                     /locus_tag="VYO94_001919"
     CDS             826..1194
                     /locus_tag="VYO94_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1760495.1"
                     /translation="MAVGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKAK
                     NMENAKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIK
                     NKSDIVKKYNEVFTDIQSKQ"
     gene            1207..1593
                     /locus_tag="VYO94_001920"
     CDS             1207..1593
                     /locus_tag="VYO94_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760496.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYAD"
     gene            1600..1689
                     /locus_tag="VYO94_001921"
                     /pseudo
     CDS             1600..1689
                     /locus_tag="VYO94_001921"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1675..2298
                     /locus_tag="VYO94_001922"
     CDS             1675..2298
                     /locus_tag="VYO94_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760497.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIRAIQHEVGITTVYVTHDQEEAMAI
                     SDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNIIPTNLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASK
                     IQVSEESTFEEELQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            2288..3933
                     /locus_tag="VYO94_001923"
                     /pseudo
     CDS             2288..3933
                     /locus_tag="VYO94_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(4036..4728)
                     /locus_tag="VYO94_001924"
     CDS             complement(4036..4728)
                     /locus_tag="VYO94_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1760498.1"
                     /translation="MVKVRLYLIRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
BASE COUNT         1536 a         1045 c          845 g         1473 t
ORIGIN      
        1 tagaattgta ggttttaaaa acgcttacat tgttttaaaa taaacttaaa taacacaacg
       61 gagatatcca tcatgaaaaa gaaatagatg tattatgctg cttgttcttc taatgaatct
      121 gccgatgaca gttcatctga taaaggagac ggtggttcgc tagtcgttta ttcaccaaac
      181 tcagaaggct taattggagc aactattcct gcctttgaag aaaaatatgg tatcaaaata
      241 gaactgattc aagctggtac tggagaactt ttcaaaaaac tagagtcaga aaaagaagtt
      301 cctgtagctg atgttatctt tggtggttct tatacacaat atgctaccca cggagaactc
      361 tttgaaaact atatttcaaa agaaaatgat aatgttatca aagaatatca aaacacaact
      421 ggcttctcta ctccttatac actagatggt agtgttttaa tcgtccaccc tgatttaact
      481 aaaggcatga acatcgaagg atatagcgac cttctcaaac ctgaactaaa aggaaaaatc
      541 gcaactgctg acccagcaaa ctcttctagc gcctttgctc aattaacaaa tatgctacaa
      601 gctcaaggtg gttacaaaga tgataaggct tggtcttatg taaaagatct tttcacactt
      661 attgatggta tagtaaaatg aaataagaac aggacaaatt aatcaggaca gtcaaatcga
      721 tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaataca ctataaaatc
      781 ggttcaagtt catctggtgt ctataaagca gtcgttgatg gagaaatggc tgttggtctc
      841 tcttatgagg atccagcagt taaactctta aatgacggag ctaacattaa agtagtctat
      901 ccaaaagaag gaaccgtctt cctacctgct agtgctgcta tcgttaaaaa agctaaaaat
      961 atggaaaatg ccaagaaatt tatcgatttt attatctctc aagaagtaca agatacactt
     1021 ggcacaacca ctactaaccg tcctgttcgt aaaaatgcta aaacaagcga aaacatgaaa
     1081 ccaattgaca aaatcaaaac actcactgaa gattatgatt atgtcatcaa gaataaatca
     1141 gatatcgtta agaaatacaa cgaagtcttt acagatatcc aatctaaaca gtaaaagagg
     1201 ttcactatga gtgagatcga aattattaac gccaaaaaaa tctaccacga tgtccctgtt
     1261 attgagaatt tgaacattac aattccaaaa ggaagtctct ttacccttct tggagcttca
     1321 ggatgtggga aaacgaccct tcttcgtatg attgcaggtt tcaacagtat caaagatgga
     1381 gaattttact tcgatgatac aaaaatcaat aatatggaac ccagcaaacg caatatcggg
     1441 ctggttttcc aaaactacgc tattttccca catttgactg tccgagacaa cgttgctttt
     1501 ggtcttatgc aaaagaaggt tccaaaagaa gaattgattc aacagaccaa caagtatctt
     1561 gaactcatgc aaattgctca atatgcggat tgaaagcccg ataaactcag tggtggacaa
     1621 caacaacgtg tcaccttggc atgcgcctta gcggttaatc caagtgttct cctcatggac
     1681 gagccactta gtaatctgga ggccaaactt cgcttggata tgcgtcaagc catccgagca
     1741 atccaacacg aagtgggaat tacaactgtt tatgtaaccc acgaccaaga agaagccatg
     1801 gctatttcag accaaattgc tgttatgaaa gatggggtga tccaacaaat cggccgacca
     1861 aaagaactct atcataaacc agctaatgag tttgtggcaa cctttatcgg acgcacaaat
     1921 attatcccta ctaatcttga aaaacggagc gacggcgctt atatcgtctt ttcagatggc
     1981 tatgcccttc gaatgccagc tcttgatcag gttgaggagc aagctattca tgtaagcatt
     2041 cgtcccgaag agtttatcaa agatgaatct ggagatattg aaggaactat tagcgatagc
     2101 gtctatcttg gactaaatac ggagtatttc attgagacag gttttgcctc aaaaattcaa
     2161 gttagtgaag aatcaacttt tgaagaagaa ctacaaaaag gcaatcgtat tcgtctacga
     2221 atcaatacgc aaaaattaaa catcttttct gcagatggtt cccaaaacct gataaaagga
     2281 gtcaaccatg gaatgtaaaa aactaaatat ttggacaacc tcctctttct tcatctttct
     2341 tacctatctt gtctttctcg tttatcctat cgttaccgtg ctcaagcaag cacttataca
     2401 tgaaggacaa ttctcactag ctaattttgt cactttcttt agtaaagtct actactctga
     2461 gacactagtc aacagtttca aggtttccat taccgctact gtcacttcct tagttgtagg
     2521 aaccctatta gcttatctct tctctatgta tgacttcaag gggaagaaat ttctacaaat
     2581 attgattatc attgcttcca tgtcagctcc tttcgtagga gcctactcct gggttctctt
     2641 gctaggacga aatggggtca tcactaaatt tttgacaaat gcccttcatc ttccagctat
     2701 cgatatttat ggattcaaag gaattgtact tgtctttaca ctgcaactat tcccactggt
     2761 atttctatat gttgctggaa caatgaacag tattgacaat tctctacttg aagcagctga
     2821 aagcatgggg tccttcggat ttaaacctat cgtaacggtt gttttacctc tcctagttcc
     2881 aaccttacta gcagctcctt gcttgtattt atgagagcat tctcagactt tggaacgcct
     2941 atgttgattg gcgaaggata tcggactttc cctgtcctga tttataccca atttattagc
     3001 gaggttggag gaaattctgc ttttgcaatt atggcgatta tcattgcctt ggcaattttc
     3061 cttatccaaa aacacattgc aaaccgctac agtttcagca tgaatctgct ccatccaatt
     3121 gagcctaaaa aaactacaaa aggaaaaatg gctgccattt atgcaacagt ctacggaatt
     3181 atctttatct ctgttttacc tcaaatctac ttaatttata cctctttcct aaaaacatca
     3241 ggtatggtat ttgttaaagg ttattctcca aacagttaca agctagcttt caatcgtatg
     3301 ggatctgcta ttttcaatac cattcgtatc cctttgattg ccttagttct agttgttcta
     3361 tttgcgacat ttatctccta cctagccgtt agaaaacgga atttgtttac aaacttaatt
     3421 gacagcctca gtatggtacc ttatattgta ccaggaaccg ttctagggat tgccttcatt
     3481 tcttccttca atactggtct atttggaagt ggatttctta tgattacagg gactgctttc
     3541 atcttgatta tgtctctatc tgtcagaaga ttaccgtata ctattcgctc atctgttgct
     3601 agcttacaac aaatagcacc aagtattgaa gaagctgctg aaagcttagg aagtagtcgt
     3661 ctcaatatct ttgctaagat tacaactcca atgatgctat cgggtatcat ttctggagcc
     3721 atcttatctt gggtcacaat gatttcaaaa ctctctactt ctatcctcct ctacaatgtc
     3781 aaaacaagaa caatgactgt agctatttat acagaggttc tcagaggaaa ttacggtgta
     3841 gccgcagcct tgtcaactat cctgactgtt ctaacagtag gttccttgct cttgtttatg
     3901 aaaatctcta aaagcaatag cattacactt tagttttcca catcaaaaac agccgaaagg
     3961 agtaccctca gctgtttttt cttatcttga tattcttatc aaatccctag ctcatggcaa
     4021 gcaagtctag actgattaaa tagagccttc ttccatcttc tcacgtccta gctctcggta
     4081 actacggtca ccgacaactt caaccctaaa ctgaccgtcc tcatattcaa gaatcgtcac
     4141 gctaccatta tctagaccat gcggatgcat gccattaatc agataaacaa tggttccaat
     4201 agtcattcca tggctgacaa caagggcgtt acctccacct tgatcttcca tttcttttgc
     4261 aatcatttca aagccttcct taattcggcc actgagtttt tcccagcctt cagcccaacc
     4321 agctgtatcg acctctacca agccctcagc cagttcagca taagacaatt ggtgaacgtg
     4381 gtccacatta aagatacgag gaataatgcc catgaaaaga tcgccatcat aggctccatc
     4441 aaaactaccg aaacaccatt ctctgatacg cttgtccatg cgataaggga ttttcccctg
     4501 caagccaagc tcttcaagga taattcccat ggtctgaatg gtacgaccag aatcactcga
     4561 ataagcgcgc tcaaactgta gatcagattc tcgcaaaccg attcctaact cttgaatccc
     4621 tcgttcacct tcagcagtta agggagtatc gctccaacct tgcgcgcgac caatcgtgtt
     4681 aaacatggtc ttgccatgac gtatcaaata caatcgtact tttaccattt tccgtcctcc
     4741 gtttgcttct attatatcat gaatgataaa ataaaagcca cccatacagg cgacttttga
     4801 aggagattat tatgaaaaag tttaggagtt cattaaataa agatattaga tgaaaatcaa
     4861 attcaaacta attcagtgtt atctgtttca aataatatt
//
LOCUS       DAVMAH010000080         4834 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVMAH010000080 DAVMAH010000000
VERSION     DAVMAH010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4834
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.081"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(86..253)
                     /locus_tag="VYO94_001925"
     CDS             complement(86..253)
                     /locus_tag="VYO94_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760499.1"
                     /translation="MSLIYSSAKKDFLYWNVLIFIMELPNDVKVQFYELRKKVQSFNQ
                     LSKRFGMDVSG"
     gene            complement(420..491)
                     /locus_tag="VYO94_001926"
     tRNA            complement(420..491)
                     /locus_tag="VYO94_001926"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(456..458),aa:Arg,seq:cct)
     gene            complement(534..881)
                     /gene="rplS"
                     /locus_tag="VYO94_001927"
     CDS             complement(534..881)
                     /gene="rplS"
                     /locus_tag="VYO94_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV1760500.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(1000..1329)
                     /gene="crcB"
                     /locus_tag="VYO94_001928"
     CDS             complement(1000..1329)
                     /gene="crcB"
                     /locus_tag="VYO94_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1760501.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1323..1697)
                     /gene="crcB"
                     /locus_tag="VYO94_001929"
     CDS             complement(1323..1697)
                     /gene="crcB"
                     /locus_tag="VYO94_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1760502.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(1694..1960)
                     /locus_tag="VYO94_001930"
     CDS             complement(1694..1960)
                     /locus_tag="VYO94_001930"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV1760503.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(2076..2519)
                     /locus_tag="VYO94_001931"
     CDS             complement(2076..2519)
                     /locus_tag="VYO94_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV1760504.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            2623..3558
                     /locus_tag="VYO94_001932"
     CDS             2623..3558
                     /locus_tag="VYO94_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV1760505.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3612..3896
                     /locus_tag="VYO94_001933"
     CDS             3612..3896
                     /locus_tag="VYO94_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV1760506.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(3953..4171)
                     /locus_tag="VYO94_001934"
     CDS             complement(3953..4171)
                     /locus_tag="VYO94_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760507.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(4195..4741)
                     /locus_tag="VYO94_001935"
                     /pseudo
     CDS             complement(4195..4741)
                     /locus_tag="VYO94_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1508 a         1049 c          845 g         1432 t
ORIGIN      
        1 tgttttaatt cagtggaata gtaacgattc ttcccttttt taacgctctc tgttcaataa
       61 cgatcaattc accttgtcac ataccttagc cagaaacatc cataccaaat ctttttgaaa
      121 gctgattaaa gctttgtact ttctttctaa gttcatagaa ctgaacctta acgtcatttg
      181 gcaattccat aataaaaata aggacattcc aataaaggaa gtccttttta gcactactat
      241 aaatcaaaga catttttatg atccatttta ttctataatc attgaccaaa atataatttt
      301 tggtcaaaat ttggtcaaaa aaattaaaaa tgctaaatta tttttaaaaa tgaacttgag
      361 aaaattgcct tcaaataaac attttgaatt ttctttgtct ttctttacat tactaaaaat
      421 gccccctgca ggaatcgaac ctgcaactac tccttaggag ggagttgtta tatccattga
      481 actaagggag ctagataaaa actctgctaa atgagcagag ttttttagtc gaattaacga
      541 cggatttctt tgatacgagc tgctttacct tgaagagcac gcaaatagta caatttcgca
      601 cgacgtactt taccgtaacg aacaacttcg attttttcaa cacgtggagt gtggattggg
      661 aagatacgct caacacctac accgttagag attttacgaa ctgtgtagtt ttctgagatt
      721 ccagcacctt tacgtgcgat aacaacacct tcaaaaatct ggatacgttc acggttacct
      781 tcgacaactt tcgcgtgtac acgaacagtg tcaccaggac ggaatgatgg gatatctgta
      841 cgaagttgac cttcagtcaa gctttggatt aatggattca ttttattctc ctatctttgt
      901 caatcttgag gaaacttcct cagcggataa actgtatttt tgtgcgtcca tcacacacaa
      961 gatacagtct accaaatttt cacaaaaaag taaagaaatt tatagcaaaa ttcctaaaaa
     1021 aatcgcaacc aaaccaccta tgtaagtcaa agtcaggtaa gaataaaaga ccttcttatc
     1081 acttagcagt ctttgaagtt cgtcattcaa ggtcgaaaaa gttgttaaac cgccacaaaa
     1141 tcctgttgct agaatagcat atacttcctt agactctaca tgattgtaga atactccaat
     1201 taaaaaacaa cctaaaagat tagctatgag cgttccaagt ggcaatttag aagcttgatt
     1261 gtagcgggaa aagaaatacc gtacgagtgc tcccaagcca caggcgattg caagatagac
     1321 gattaccatt tcttcctccc caaatagtaa gctaaaagca ggcctccacc gatactcaaa
     1381 agcaaataca gtatcaaact aagataacgc cctgtatcaa gcagcttcac agtatcaagc
     1441 attaggctgg aaaaagttgt taaacctccg caaaaacccg tccccagtgc taaaatcaag
     1501 cccttactag tccccttata gaccagatag cccttgacaa gataaatcaa gcagaaaatt
     1561 cccagatagt tgacaaagag agtgccccaa gggaaatctg gactggctgg taaccaagtg
     1621 gaaactaggt agcggacaag tccgcccaac atagcagcta gaaaaatccc tagcggataa
     1681 aattgttctt ttttcatttg atattttgat cctgataatc acgcgaacgt ttgagtatgt
     1741 ccgaaaaagt cgcgacaata gtctcctgat agcgcttgtc ctctacacga cttctaacct
     1801 tttcaaaaat aactgcttct ctcttagtat ctaaaatcgg tttccctgaa gccttcttat
     1861 aagcgacaac tccttcaact aagtgcattc gttcttctaa cagtttgaca atttggtcgt
     1921 cgatttgatc gatttcttga cgaataatat ctaaatccac acagtctcct cctttatttg
     1981 aattattgta tcaaaaagcc atcaattagg ctagtaaaat cccaactctc gataagaaaa
     2041 atgcactgat tgattacatc agcgcacttt tatgcttatc ctactttagc aaccaattct
     2101 tctgcgaatt gttccaagcg ttcaatatct tcttcctcgg cagaaagatc aactttaaca
     2161 cactctgaac ctttttctgc tcctgttgac acaaagacac ggtcaaagtc atcaacagcc
     2221 ttacagaatt catcgtagaa ggtatctcct gagccgacca ctccgtagat tttgccattc
     2281 aagttgagat ctgctaggtc ttcgtagaag tccatcatct catctggcaa ttcaccatca
     2341 ccataagtat aggtcgcaac gatagcgatg tctgcttcca agaagtctga agcgtcaaca
     2401 gttgtacatt catcaacatc aacatccaag cccaagtcac gtaatttgtc tgctacaata
     2461 tctgcaattt cttcggtatt accggtcata ctggcaaata caatttttgc taatgccata
     2521 tcgtcctcct caatttatct ttctccatta tatcacatct ttttcatttt aaaaataaaa
     2581 attcttgtgc tacaatgaaa tgagaaagaa ttgaggttat ttatggagat ttgccaacaa
     2641 attttagaaa aaattaaaga atacgacacc attatcattc atcgtcatat gaaaccagac
     2701 cctgatgcct tgggaagtca ggtgggattg aaagccttgc tggaacatca tttcccagaa
     2761 aaaaccatca aagccgtcgg ttttgatgaa ccaactctta cttggatggc tgagatggat
     2821 cttgttgaag atagggccta ccaaggcgca cttgtcatcg tctgtgatac agctaatact
     2881 gctcgtatcg atgataaacg ctatagtcaa ggtgattttc tcattaagat tgaccaccat
     2941 ccaaatgatg atgtatacgg tgacctgtct tgggtcgata ctagttcaag tagcgctagc
     3001 gagatgatta ccctatttgc ccaaacaacc caactagcct tggcagatcg cgatgctgag
     3061 ttgctctttg caggaattgt cggtgataca ggtcgcttcc tctacccttc taccactgca
     3121 cggactcttc gcctggctgc ttatttgaga gaacataact ttgactttgc agctctcact
     3181 cgcaaaatgg acactatgag ctacaaaatt gctaaactgc aaggctacat ctacgaccat
     3241 ctggaagtgg atgaaaatgg tgctgctcgc gttatcctga gtcagaaaat cttgaaacaa
     3301 tacaatgtaa ccgatgctga aactgcggcc attgtaggtg cacctggacg cattgacaga
     3361 gtgagtctct ggggaatttt tgtcgaacag gctgatggcc actaccgagt tcgcttacgc
     3421 agtaaagtcc atcctatcaa tgaaattgcc aaggagcatg atggtggagg ccaccctcta
     3481 gcaagtggtg ctaattccta tagcctagaa gaaaacgaaa tcatctacca aaagttaaaa
     3541 aacttgctta aaaactgata aaatacttgc caaacttttc agaatctgat agactagtat
     3601 ggtaacaatc tatggctcgc aaagagacca tggcagaaag gaaatattgc aaaatgaaaa
     3661 aagatatcca tccagaatat cgcccagttg tcttcatgga cacaactact ggttaccaat
     3721 tccttagcgg ttcaacaaaa cgctctaacg aaacagttga gttcgaaggc gaaacttacc
     3781 cattgatccg tgtggaaatt tcatcagact cacacccatt ctacactgga cgtcaaaagt
     3841 tcactcaagc agatggacgc gtggatcgtt tcaacaaaaa atacggtctc aaataatgat
     3901 aagagaacag tttcggctgt tcttttttgt ttcttgaaat caactgctgt tttcatgttc
     3961 cagactcatc tgtaggttcg gtttccatgc tactaggcag gaaggaaata gctgtttcaa
     4021 cacgtccata atgagctgta ctattgtcac gaaccacact ttcattgatg gtccaagtgg
     4081 aattcatttt cttaaaagct tctcggactt tttccaaatc tttggaggca atggcctgct
     4141 ctaaggtttc aaaacgagga cttatactca tctgctttca caaagcattc tagttcatct
     4201 ccgattaacg atggacttta tcacctcctt ctccagtcct tgtatgacat cttgaagttg
     4261 attcatgata tcttccaaag ttcgaaaggc tttattctta aatccacgtt tacgaatctc
     4321 tttccacact tgttcaatgg gttcatctct ggtgtgtatg gaggaataaa ggtaaaatca
     4381 atattagtcg gaatatttaa ggtacttgat ttatgccata tagcattgtc cataacgagt
     4441 aaaaggataa gcttgtgaaa gctcttctaa aaaggcgttc atccacactc ctttttataa
     4501 gcctgaaata aggcatcaat tgtaacaaat tctcctgcct ctgtagcctt caaatgacgg
     4561 gcaagaaagg ctttctcttc ctcaactgtc atatatgcat ggttacgacc accacgtgtt
     4621 tcttgaaaga gagagtcgag tccgaactcc tcatattttt tacatttcgc taaatcgttg
     4681 tttgattaca gtctaaaagt tctataatct ctttataaga tttgcccatc agacgaaata
     4741 tagtagattg aaactagaat agtacacctc tacttctaaa acattgttag aaatcgattt
     4801 gactgtccta atcgatttgt cctgttcttg tttc
//
LOCUS       DAVMAH010000081         4829 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVMAH010000081 DAVMAH010000000
VERSION     DAVMAH010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4829
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.082"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(386..1114)
                     /locus_tag="VYO94_001936"
     CDS             complement(386..1114)
                     /locus_tag="VYO94_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1760508.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1272..2681
                     /locus_tag="VYO94_001937"
     CDS             1272..2681
                     /locus_tag="VYO94_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1760509.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKKHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAIIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2699..3994
                     /locus_tag="VYO94_001938"
     CDS             2699..3994
                     /locus_tag="VYO94_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1760510.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3999..4307
                     /locus_tag="VYO94_001939"
     CDS             3999..4307
                     /locus_tag="VYO94_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1760511.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4304..4612
                     /locus_tag="VYO94_001940"
     CDS             4304..4612
                     /locus_tag="VYO94_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1760512.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEVHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1634 a          814 c          890 g         1491 t
ORIGIN      
        1 ttaaaagaag atatgaacaa ataaattggg agattgaaat tcatttctag caatttttta
       61 gaagtcacag tctactattc taacctcagt atactatatg tgttacaaga aaagactcaa
      121 aaacttctcg tcagtgtaag aatgtttgaa acactattta aaactaaata actataagaa
      181 gtagatcaag tgaacaattt cagtacctac tctataagct atacgaagat atttttcaac
      241 atgatggata aaacgatcac tcttttaaag ccatcttatt tagaaaagag aaaccattta
      301 agcatagatg gaaccttctt gccctgtttt aaatttttct taaactagag tctgtaaaag
      361 attggcttca ttttcacatt ttctcctagg aggaatgtcg taatgcaaaa gaattaaatt
      421 caaataaatc atagcgatga cgactaatcg agtactcaaa cggagttccg ttatccaaat
      481 aagccacttg ttctacttca aataccggtt ccgttggaag gagctgcaag taatgttgct
      541 cattttctga actagaagaa gctcgtaaga tttttgtagc actggcaata tgcaatccta
      601 actttccttc aatgtaattg taaatcgatt tttgtaaaat atcttcagta atacctggaa
      661 taacatcggt actcatataa gtttgttcca gaacataagg tttaccgtca ataatacgca
      721 ggcggtaaat attataaact ggactctgca aagcgacctg tagtttttct gctaaaaatt
      781 catttgcaaa ttctaatttg aagtgaataa tcctcgagtc aattgtagaa tgagcatctt
      841 cagatatttt tgtcagtccc cggatatctc tttctggaac gattaatttt ctttttgagc
      901 tgccacgaga gagaacaaag gttccctgcc cacgttttct aaaaattaag ccctcagaaa
      961 ctaacaagtc taaagctttt ttgatcgtca ttcgactaca ggcaaactgt ttagctaatg
     1021 tcatttcatc aggcaattgt tcgttcatgg tatatttatt acaaagaatc ttttcacgaa
     1081 tctcattgta aataaataaa tattttgtac tcatttaatc tggttctctc tataatattc
     1141 taatagtagt ataacaaagt tcaagaaatg aggcaaacac aagatatgta tcaacaattt
     1201 ttaaaattgt ctagacaaat tttaaaatta tgctatactt tatgtataga ataatagaaa
     1261 ggaggttgag catgaaaaaa aagttagtat ttcctaatct gttttggtgg ggagctgctt
     1321 ctagcggacc tcagacagaa ggtcaatatg gaaaagtaca tgaaaatgtg atggactact
     1381 ggttcaaaaa gcatccagaa gattttttcg ataatgtcgg acctcttgta gccagtaact
     1441 tttttcatac ttacaccgaa gatttccact tgatgaagga aattggagtt aattctttcc
     1501 gcacttccat ccaatggagt cgactcatca agaatttaga gacaggtgag cctgatccaa
     1561 aaggtattgc tttctacaat gccatcattg aagaagctaa aaagaaccag atggatcttg
     1621 tgatgaattt acatcatttt gatttaccag tggaacttct tcaaaaatac ggtggttggg
     1681 aaagcaaaca tgtagtggag ttattcgtga agtttgccaa gactgctttc acatgctttg
     1741 gagataaggt tcattactgg acaactttca atgagccaat ggtcattcca gaagcaggat
     1801 acttatatgc tttccattat ccaaatctaa aaggaaaggg aaaagaggcc gtacaagtca
     1861 tctataatct aaaccttgct agtgcaaaag tgattcaact atatcgctca ttaggacttg
     1921 atggaaagat tgggattatt ttaaacttga cacctgctta tccaagaagt aattctccag
     1981 aagacttaga agcaagtcga tttacagatg acttctttaa caaagtcttc ttgaatccag
     2041 ctgttaaagg aactttccca gaaagattgg taaaacagct agagagagat ggcgtgttat
     2101 ggagtcatac cgaaaaagag cttcaactga tgaaatcaaa tacggttgat tttcttggag
     2161 taaactacta ccatccaaaa cgtgttcaag cacaagcaaa tcctgaggaa tatcagacgc
     2221 cctggatgcc agaccaatac ttcaaagagt atgaatggct ggagcgtcgc atgaatccat
     2281 atcgtggttg ggaaattttt ccgaaagcca tttatgatat tgctataatt gtgaaggaag
     2341 aatatggtaa tatcccatgg tttatcagtg aaaacggaat gggtgttgaa aacgaagcac
     2401 ggtttatcga tgaaaatgga gttatcgatg acgtgtatcg tattgaattt tatgaagaac
     2461 atttaagatg gctacataaa gccattgaag agggaagtca ctgttttgga taccacgctt
     2521 ggaccgcatt tgattgctgg tcttggaata atgcatataa gaatcgttac ggatttatct
     2581 ccgttgattt agaaacgcaa aagagaacca tcaagagctc aggaagatgg tatcgcaaag
     2641 taagtgacaa taacggtttt gaagtagaaa ttgaggagta aagagaggag atattcatat
     2701 gaaaaactca aaatttatag accaatttgc cacctttgct ggtaaactag ggaaccaaat
     2761 tcatttaaaa accctaagag atgcattcgt aacagtaatg ccattatata ttttggcagg
     2821 tttaatcgtt cttttgaaca acacggtatt taagtggatt ttccaagggg atacattaac
     2881 aagattccaa tattggggaa taacaattgc aaacggtact ttaagtattt caggtatgat
     2941 tattgctgta atggttggtt atttcttagc taaaaacaga gatttcgaaa acccgttagc
     3001 agcatcaatg ctatcattag tttctttaat tgtgatgatg ccaaatacag tttctgtagt
     3061 tcctgacgga gcaaaagatg cggtaaacat ttcaggtgtt ctttcattca acaacacagg
     3121 tacaggcgca atgttcgccg gggttatcgt agcgattatt gcaacagaat tattcattga
     3181 attatcaaat gttaaagctt tacaaatgaa ccttggtgaa aatattccac cagctgttag
     3241 tagatcattt agcgtattac ttccagtcat gaccgtcatc tccttatttg gggttgtttc
     3301 agcattatta ttcaatataa ctggaatgaa cttaatctca atcattacaa tctttattca
     3361 agaaccaatt cgtcatattg gtacaagctt aatcggggtc attattattt actctttagg
     3421 aaatatgtta tggctatttg gtattcacca agcagttatt tacagtgcca tcctagaacc
     3481 attactatta attaacatta ctgaaaacat cactgcagca aataatggac aagccattcc
     3541 acacatcatc aacctatcac aaatacaaac attcgcttta atgggtggta gtggatctac
     3601 attatgttta ttaatagcaa cattcttagt gagtcgcaat gctgtctcta aaaacgtggc
     3661 taaattatct tttggacctg gtatcttcaa tatcaatgaa ccagtattat tcggttaccc
     3721 aatcgtttat aacatttcat tagctattcc atttatcaca gttccagtcc ttggtatttt
     3781 aatcagctac ttagcaacag ttacaggatt catgagtcct gcatttatac aagttccttg
     3841 gactacacca gtattcttaa atgcatggtt agcaacagca ggggacgtga gagcagttct
     3901 agttcaattc atcatctttg cacttggagt tcttctatac attccattta tcaaagttaa
     3961 tgacaaagtt gttgaacaag aaatggaagg ttaagattat gaaacaaatt ttattagtat
     4021 gtaatgcggg aatgtcgaca agtatgcttg ttaaaaaaat gcaacaaagt gcgactgaac
     4081 gtgggattga aatttctatc caagcaaaat caatgacaga agctaaaaag aatatccatg
     4141 aagcagatgt cattctaatt gggccacaaa ttcgttatga gttacttgct gtgaaagaaa
     4201 ttgcaggaaa tatccctgta gataccattg atatgcggga ttacggaatg atgaatggag
     4261 caaaagttct ggaacaagca cttgcatgga taggagaaat aagatgacag aagaaatgga
     4321 atatatctgt tttcagctca ttgccaatag tggagcagcc aaatcatcct ttattgaagc
     4381 catccaacta gctaaggcag gaaatttaaa agaagcgaaa attaaagttg aagaagcgga
     4441 agactcctta gtagaagtgc acaagattca ctctaatctc atacaaaaag aagctactgg
     4501 agaaaaaata ggattctcct tgctatttat gcatgcagaa gaccaaatgg cttcaacgga
     4561 gattattcag ttgctatcta aagaattcat cgatctctat caaaataaat aggaacactg
     4621 tcgttcccat ctgtctttat taatgacgac tacattgtag gaacctccaa aagttggaca
     4681 aaatgattga aaggattgga tcctgcatta cacaagatcc aatccttttc ttttactcta
     4741 gtttttataa tatgttgaat ctagaatagt ccactgtagt ttctaaaaaa ttgctggaaa
     4801 tggatgttaa gctccaattt atttgttta
//
LOCUS       DAVMAH010000082         4617 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVMAH010000082 DAVMAH010000000
VERSION     DAVMAH010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4617
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.083"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(287..838)
                     /locus_tag="VYO94_001941"
     CDS             complement(287..838)
                     /locus_tag="VYO94_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760513.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(1188..2012)
                     /gene="nadE"
                     /locus_tag="VYO94_001942"
     CDS             complement(1188..2012)
                     /gene="nadE"
                     /locus_tag="VYO94_001942"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV1760514.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAIEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGFHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(2009..3469)
                     /locus_tag="VYO94_001943"
     CDS             complement(2009..3469)
                     /locus_tag="VYO94_001943"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV1760515.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(3585..4073)
                     /locus_tag="VYO94_001944"
     CDS             complement(3585..4073)
                     /locus_tag="VYO94_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760516.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(4063..4272)
                     /locus_tag="VYO94_001945"
     CDS             complement(4063..4272)
                     /locus_tag="VYO94_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1760517.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
BASE COUNT         1318 a         1065 c          855 g         1379 t
ORIGIN      
        1 attccctaac tcgatagagg attctatttt aaatttaaca acagctagga ttacactata
       61 aaaagtacat taccacctgt tcggctggag aatctagtcg attagctccc tcttagttac
      121 aagcttaaag cgctttttta actaatacta aaccagatta aagaaggaac tagaacatct
      181 gtcttgtact aatcaatatg ctattttaaa attgcaaata aacttggaat gctaattatt
      241 atatttacaa taaatagttg acttcgatag aaacagaaaa tagaattcaa cattcttccc
      301 tacttatacc ataataaata agatccgcaa gatagccttt tctctctaca ccattaacaa
      361 tggtttgtag ataggacatt ccagcctttt ccatgacacg acctgaagct gggttgagac
      421 tggcataacg tgctctgacc ttttgaaaac ctgcttgagt aaaacaaaag tccaagacag
      481 ctttcaaggc ctctgtcatc ataccatgtc cccagtaagc cttgcctagc acatagccga
      541 tttcacagct taaatcagcc tcgtctatct taacgatgct gatatctcct atcacttgct
      601 ctgggttttc ttttagacaa atggcccatt tgtaatagtt gagattagta taggaagcaa
      661 cccaattgcg aatcgagttt cgagtgattt cgacatcagg atggggatcc caggtaacat
      721 aggtcagatt ctcagcggat gaagcccaat tttgaaacat ggcttctgca tcactctcca
      781 caaatcttct taaaatcaaa cgttctgtct gtaatatttg cgtaccgata gatttcatga
      841 tgctacctca cttccttatt tctatgctcg tagtaaaaag gctcaactca gtaacagcta
      901 gaaaacgagt ttgtcttcta atttcttgac gcagtcgctg cctggtttga aatgcgctct
      961 agcaagcttt ttcaaaccta gtcatcgttg caggggtaag acgatgaaat cgaactcttc
     1021 gagttaccga atctgcctca ttttcttatt tctaaactcg gggttcaaga tcccccagac
     1081 cttctctcac tttcttattt caagatgaga ggctgaaaac ctccaataga ggtttttctt
     1141 gctttttaat ttcagggcaa gaagctaaaa aggtcccccg gaccttttta ctcccaaaag
     1201 tcatcaaata cggtgatggg taagtggcgt ttgtgttggc ctttgtgcca ccagttttca
     1261 atggtcgctt gagcttctgg gctgattgtt ttgccttcta ggtagtcgtc aatctctgcg
     1321 taggtgactc caagtgcgac ttcgtcagct aggcctggtt tatcttcttc taggtctgct
     1381 gttgggattt tttcataaag ggctggctct gcgccaagtt tctgcaagag ctgttttcct
     1441 tggcgtttat tgaggcggta aagagggaga atatccgcac cgccgtcacc aaacttggta
     1501 aagaaacctg tgatattttc cgcggcgtgg tctgttccaa tgaccgctcc gctatggaaa
     1561 ccagcaaggg catactgagc aatcatacgg caacgtgcct tgatattccc cttgttgaag
     1621 tctgaaacag gactacctgt cgcttcaact gcagctgtca tagcatcagc tgactccttg
     1681 atattcacaa ccaagctgac atctggctgg atgaaggcta gggctttttg agcatctgct
     1741 tcatcagctt gcactccgta tggcaggcgg acagcgataa atttgtagct gtcgtctccc
     1801 gtttcagctc gcagttcttc tatagctaat tgcgccaaac gtcctgccaa ggttgagtct
     1861 tgtcccccag aaatccctag tacaaaggtt tttaggaagg gatgtttttt cagatatctt
     1921 tttaagaaat caatagaacg acggatttct tcctgggcat caatcactgg tttgacaccc
     1981 agctcttgga taatcgtttc ttgcaaactc attcttcttc tccttcacca agggcttcct
     2041 tgcgcatctt atcaatcaag tccatcttat cttgccatac atcacgtgcc aaatccactg
     2101 gatagtgctg cggattgagc acacgcttat actcatccca caacttgtca aattccttac
     2161 gggcataatc ctgaatgtca gtcaaactag gcaagttgta aactaatatt ccttctttga
     2221 agatatccac caagagagga acggcatcaa aattacgaac cgtcttcttg atgtatgtat
     2281 aggtcggatg gaacatcttg atttctgtca tgtcgctaat atccacacca tcataagtga
     2341 tatagtcgcc ttctgacttg cctttttcac gactggtaat gcgccacacc tgcttcttac
     2401 ctggcgtcga cactttttcc gcattattag acagcttaat cgtattgcgc atctgaccag
     2461 tttcatcttc aattgcaaca atcttgtaaa ctgcaccaag agctggctgg tcataagctg
     2521 taatcagctt ggtacccacg ccccagacat caatcttggc cttttgcatc ttgagattga
     2581 ggatagtatt ttcgtccaaa tcattagaag cataaatctt agcctctgta aatccagcct
     2641 cgtccagttg ctgacggact ttcttagaaa tgtaggcaat atccccagag tcaatccgca
     2701 cacccataaa gttaatctga tcacccagct cacgcgccac ctgaatggca gctggtacac
     2761 cgatgcgaag ggtgtcatag gtatccacaa gaaagacaca atttttgtgg gtcgcagcgt
     2821 aagccttgaa agcttcatag tcatttccat aaacctgtac caaggcatgg gcatgggttc
     2881 ccaaaacagg aatgtcaaag agcttacccg cacgcacgtt gctggttcca ttggcgccac
     2941 caatcaccgc tgcgcgtgtt ccccagatgg ccgcatccat ttcttgagcc cgacgtgtcc
     3001 caaactccat caagggttca tcttcgataa ccgaacgaat acgagctgcc ttcgtcgcca
     3061 ccaaggtctg gtagttgacg atgttcaaaa gagccgtttc gaccaactga cattgggcta
     3121 gaggtccttc cacctgcaca atcggttcat tagcaaaaac caaatcccct tcttgggcag
     3181 aacgaacggt caactccaac ttgaaattgc gaaggtaatc caagaacgcc ccatgataac
     3241 caagcgactc caaataggct atatcactat ctgaaaaacg caagtcttca agatagttca
     3301 caattctttc caaacctgca aaaaccgcat agccgttctt aaaaggctgt tggcggaaat
     3361 acacctcaaa gaccgccttc ttattgtgaa tcccttggtc aaagtaaacc tgcatcatgt
     3421 tgatctggta caagtccgtg tgcaatgtca aactatcatc tggatacata cttttcctac
     3481 ttccttagct agaaacccat gaaaattttc aagaactttc atgtattcca ataaattagt
     3541 actattatat cacattttag ctggattgag aaaagagtaa caagctattc tccactctcc
     3601 aattcatcca tatcttgttc aaattttttc tgagcccatt cgccatagct cttaagacca
     3661 agattgccaa taaagaccca cggaaggtaa atgacataag taatgaccca agcagacagg
     3721 tatttaaaat tcaaaggatt gtgctgataa atttctatgt tgaattgata attctgcaac
     3781 atcaaaagag ccgtaatagc caaggttagg aaaaaacaac ccaaaatcgt aaaatgaaaa
     3841 cgactatagt aggtcactcc cagataacgg gcacgattga aaaagtaaaa tgtccctatg
     3901 atgataacga ttagcagcat attagaatta aaaaggcttg gtgctaatac tgaaatgata
     3961 taagatagga gcgacaaagc aatgcagata tagaaacttt cagagcccgc tttattgaac
     4021 agttgttctt ctctttcgtc tagtaattga taataataaa atctattttt catcttcttc
     4081 ctcccaaaat agttggtcta gggttttccc taaacatctg caaatggact ggcagagcga
     4141 gagactggga ttgtatttcc ccgcctctat caaaccaata gtctggcgtg tcaccccgac
     4201 agcctctgcc agttgacctt gtgttaaatc acgctctacc cgagctaatt ttaattttaa
     4261 atttttagcc accttcgtcc tccttatagt tttaatactc atctactctt aaaaaatcca
     4321 aaaccaacac aagctatcag ctatttatta taaccccatt aatttgcact ccagtattat
     4381 cttcagccga aaatcagtat tttaggttgt ttgaaataaa cttcctagtt tactctttta
     4441 tttttattta gtattagctt tagtagaatc ttttaaacga gtttttattg cttatatttc
     4501 ttgtttagtt tagttggttt catatcacta ttatataatg cttttggaaa tgagcctagt
     4561 ataagtcaaa aacgtgttga atagtgaaag caggagcata ccaagatgac tgatttt
//
LOCUS       DAVMAH010000083         4379 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVMAH010000083 DAVMAH010000000
VERSION     DAVMAH010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.084"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            308..1594
                     /locus_tag="VYO94_001946"
     CDS             308..1594
                     /locus_tag="VYO94_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1760518.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMKELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     KGEILEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQNLVDEMWKVAQRELATGFYYGTPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            1609..1920
                     /locus_tag="VYO94_001947"
     CDS             1609..1920
                     /locus_tag="VYO94_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760519.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            2155..2883
                     /locus_tag="VYO94_001948"
                     /pseudo
     CDS             2155..2883
                     /locus_tag="VYO94_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            3318..4109
                     /locus_tag="VYO94_001949"
     CDS             3318..4109
                     /locus_tag="VYO94_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760520.1"
                     /translation="MNFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     IGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTKPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILISSHKL
                     EDIEEICERVLFLESGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            4125..>4379
                     /locus_tag="VYO94_001950"
     CDS             4125..>4379
                     /locus_tag="VYO94_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760521.1"
                     /translation="MKLNKQKNRMIYVLSNFLYAISVSIIYALNGIVLLVIVSKLGIP
                     GDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYKLKSGLVFG"
BASE COUNT         1430 a          674 c          899 g         1376 t
ORIGIN      
        1 taaaaaagcg atattctaga ctgtatcaat ccttttccat tataggagca acagagtggg
       61 agtagtcatc taaggactaa tttatgtatt tttacgagtc agtatctttg gatactggtt
      121 tttacttttc tagacttttt gactacttgt taaaactggg ataattttcg actgtttaac
      181 agttattatg caaagtctaa aagattagaa ttgtcaaaac aatccgtcta ggcttgattt
      241 tatcctttat ttactataaa atgagaagga aaaatgtcaa acttttatat tgcaaatagg
      301 agaaatcatg acaaaaacat taaaacgtcc tgaggtttta tcacctgcag ggactttaga
      361 gaagctaaag gtagctgttc agtatggagc agatgctgtc tttatcggtg gtcaggccta
      421 tggtcttcgt agccgtgcgg gaaactttac tttcgaacag atggaagaag gcgtgcagtt
      481 tgcggccaag tatggtgcca aggtctatgt agcggctaat atggttatgc acgaaggaaa
      541 tgaagctggt gctggtgagt ggttccgtaa actgcgtgat atcgggattg cagcagttat
      601 cgtatctgac ccagccttga ttatgattgc agcgactgaa gcaccaggcc ttgaaatcca
      661 cctttctacc caagccagtg ccactaacta tgaaaccctt gagttctgga aagagctagg
      721 cttgactcgt gtcgttttag cacgtgaggt ttcaatgaaa gaattagctg aaatccgcaa
      781 acgtacagat gttgaaattg aagcctttgt ccatggagct atgtgtattt catactctgg
      841 acgttgtact ctttcaaacc acatgagtat gcgtgatgcc aaccgtggtg ggtgttctca
      901 gtcatgccgt tggaaatacg acctttacga tatgccattt gggaaagaac gtaagagttt
      961 gaagggtgag attctagaag aattttcaat gtcagccgtt gatatgtcta tgattgacca
     1021 cattccagat atgattgaaa atggtgtgga cagtctaaaa atcgaaggac gtatgaagtc
     1081 tattcactac gtatcaacag taaccaactg ctacaaggcg gctgtggatg cctatcttga
     1141 aagttctgaa aagtttgaag ccatcaaaca aaacttagtg gacgagatgt ggaaggttgc
     1201 ccaacgtgaa ctggctacag gattttacta tggtacacca tctgaaaatg agcagttgtt
     1261 tggtgctcgt cgtaaaattc ctgagtacaa gtttgtcgct gaagtggttt cttatgatga
     1321 tgcgacacaa acagcaacta ttcgtcaacg aaacgtcatt aacgaagggg accaagttga
     1381 gttttatggt ccaggtttcc gtcattttga aacctatatt gaagatttgc atgatgccaa
     1441 aggcaataaa atcgaccgcg ctccaaatcc aatggaacta ttgactatta aggtgcctca
     1501 acctgttcaa gctggagaca tggttcgtgc attaaaagaa ggactcatca atctttataa
     1561 ggaagatgga accagcgtca cagttcgagc ttaagaaagg aaaaggaaat gatagaggca
     1621 cagggtttct tagtggataa gcaaacaaga tgcattcatt accatagcaa gctggatatt
     1681 attgctttac aatgctatga ttgtaaaaag tactatgctt gttatcggtg tcatgattca
     1741 ttagaaaatc acccttttga gccgtatccc ttatctttga tacaggataa gcctatttta
     1801 tgtggtgttt gtctaaaact actaacatat aagcaatata aagaaagctt aagttgcccc
     1861 ttttgttttt ctcgctttaa tccaggttgc caaaatcata aggaacgcta ttttaaatag
     1921 caaatcatct agttttgaag taggagaaaa ctcaattcca agagaaaatg aagtaaatct
     1981 tcccacaata aaacgcataa tatcaagatt gttcaatacc tgatactatg cgtttttaag
     2041 attttaaaga cttttttcct ttatctggta ttttgactac ttgttaaaac tgggttaatt
     2101 ttcaactgtt taacagttat tatgcaaagt ctaaaagatt agaattgcgt ctagagtatg
     2161 cgtgatgcca accgtggtgg atgttctcag tcatgccgtt ggaaatacga cctttacgat
     2221 atgccatttg ggaaagaacg taagagtttg cagggtgaga ttccagaaga attttcaatg
     2281 tcagccgttg acatgtctat gattgaccac attccagata tgattgaaaa tggtgtggac
     2341 agtctaaaaa tcgaaggacg tatgaagtct attcactacg tatcaacagt aaccaactgc
     2401 tacaaggcgg ctgtggatgc ctatcttgaa agtcctgaaa agtttgaagc tatcaaacaa
     2461 gacttggtgg acgagatgtg gaaggttgcc caacgtgaac tggttacagg attttactat
     2521 ggtacaccat ctgaaaatga gcagttgttt ggtgctcgtc gtaaaattcc tgagtacaag
     2581 tttgtcgctg aagtggtttc ttatgatgat gcgacacaaa cagcaaccat tcgtcaacgg
     2641 aacgtcatta acgaagggga ccaagttgag ttttatggtc caggtttccg tcattttgaa
     2701 acctatattg aagatttgca tgatgccaaa ggaaataaaa tcgaccgcgc tccaaatcca
     2761 atggaactat tgactattaa agtcccacaa cctgttcaag ctggagacat ggttcgagct
     2821 cttaaagagg ggcttatcaa tctttataag gaagatggaa ccagcgtcac agttcgtgct
     2881 taatgtagtt gtttagtttt aaaaaattat gcaaagctcc atatacaaca cttaaacgag
     2941 attaaagaat ggcgaaatcc cctgatgcgc aagagattag ctgtcttttt tattttttaa
     3001 gtgataaagt cggagcttag gtatcaaagc ctatcaaatt aaacaaagaa gcgatgtctt
     3061 agatattttg aaaaaaatta ataagcagaa aactctctat tattttgttg tagagagttt
     3121 tttgttaata aaattttaca aaatgacatt tatatattgc attaagttag atatatgata
     3181 taatgttgtt aaaaagaggc gcaacttttt aaactcaata agaatcaaag agcaaaccat
     3241 gaatattaat ggaggaataa aaaatgtaag ttataaatgt aagtaagcat tatggtcatt
     3301 caatcattct caaagatata aattttgcac ttaacaaggg tgaaattgtt ggtctagtag
     3361 ggagaaatgg agttggtaag agtacgttga tgaaaattct tgttcagaat aatcaaccga
     3421 cttcaggtaa tattataagc agtgataata ttgggtattt aatcgaagaa ccaaaattat
     3481 ttttatctaa aacaggttta gagaatttaa aatatttgtc aaatttatat ggtgttgact
     3541 acaatcaaga aagatttaga agtttgatcc aagagttaga tttgactcag tctattaata
     3601 aaaaagtaaa gacctattct ttgggtacaa aacaaaaatt agctttgctt ctaactctcg
     3661 ttacgaaacc tgatatattg attttagatg aaccgactaa tggtttagat attgaatcat
     3721 cacaaatagt tttagcggtt ctaaaaaaat tagctttaaa tgaaaacgtg ggaattttaa
     3781 tatcgagtca taaattagaa gacattgaag aaatttgtga gagggttctt ttcttggaga
     3841 gcgggctttt gacatttcaa aaagtaggaa aagatagtca taatttcttg tttgagatag
     3901 ctttttcatc agctacagat agagacattt tcattaccaa acaagaattt ggggatattg
     3961 ttcaggaaga gggactgaga attactatgt ctgggaatat tcaaagtagt gagcttttta
     4021 aattttttaa cgaaaactct attaaagtag ttgattttga aactaaaaaa gagacgctta
     4081 aagatattta cttaaatcgt tcaaaataaa ggaaggttat aatcatgaaa ttaaataaac
     4141 agaagaatcg gatgatttac gtcttgtcta attttctata tgctatctca gtttccatta
     4201 tttatgcttt gaatggcatt gtgttactag tcatagtaag taaattgggt attccaggtg
     4261 atttaggatt agattttata gtagctattg tagtcaatac aattttgtta gtcctgtttt
     4321 attttctatt atcttacatt ttctatttat acaaattgaa aagtggcttg gtatttggt
//
LOCUS       DAVMAH010000084         4279 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVMAH010000084 DAVMAH010000000
VERSION     DAVMAH010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4279
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.085"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..1022
                     /locus_tag="VYO94_001951"
     CDS             <1..1022
                     /locus_tag="VYO94_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1760522.1"
                     /translation="NKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDHAF
                     GQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKELN
                     GKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQTLW
                     RDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAADTS
                     KFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITYGD
                     DKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLGNA
                     CKNAK"
     gene            1012..2019
                     /locus_tag="VYO94_001952"
     CDS             1012..2019
                     /locus_tag="VYO94_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1760523.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2019..3026
                     /locus_tag="VYO94_001953"
     CDS             2019..3026
                     /locus_tag="VYO94_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1760524.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3026..3820
                     /locus_tag="VYO94_001954"
     CDS             3026..3820
                     /locus_tag="VYO94_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760525.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVMANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
BASE COUNT         1550 a          629 c          725 g         1375 t
ORIGIN      
        1 aaaacaaatt ttttctaata gctattttag ctatgtgtat agtttttagt gcttgttctt
       61 ctaattctgt taaaaatgaa gaaaatactt ctaaagagca tgcgcctgat aaaatagttt
      121 tagatcatgc tttcggtcaa actatattag ataaaaaacc tgaaagagtt gcaactattg
      181 cttggggaaa tcatgatgta gcattagctt taggaatagt tcctgttgga ttttcaaaag
      241 caaattacgg tgtaagtgct gataaaggag ttttaccatg gacagaagaa aaaatcaaag
      301 aactaaatgg taaagctaac ctatttgacg atttggatgg acttaacttt gaagcaatat
      361 caaattctaa accagatgtt atcttagcag gttattctgg tataactaaa gaagattatg
      421 acactctatc aaaaattgct cctgtagcag catacaaatc taaaccttgg caaactttat
      481 ggagagatat gattaaaatt gattcaaaag ccttaggtat ggaaaaagaa ggtgatgagt
      541 taatcaaaaa tactgaagct cgtatatcca aagaattaga aaaacatcca gaaatcaaag
      601 gaaaaatcaa aggaaaaaaa gtattattta ctatgattaa tgctgcagat acatcaaaat
      661 tctggattta tactagcaaa gatccaagag caaattattt aacagattta ggtctagttt
      721 tccctgaatc attaaaagaa tttgagagtg aagatagttt tgcaaaggaa atttctgcag
      781 aagaagcaaa taagataaat gatgctgatg taatcataac ttatggtgat gataaaactc
      841 ttgaagcttt acaaaaagat cctcttttag gtaaaataaa tgcaattaaa aatggtgccg
      901 ttgctgtaat tccagataat acaccgttag cagcctcatg cactccaaca ccactttcaa
      961 taaactatac tattgaagaa tatctaaatc ttttaggaaa tgcatgcaaa aatgcgaaat
     1021 aaaaaacaaa taaacctagg cataattttt gtaatctgcc taggtcttct tattacaata
     1081 tttttgtcat taaagcttgg aacaaaagaa attaatatca gagatttttt agcagctttt
     1141 ggaatgggta atacaaatga tgattttatt aaatcaatta tatataaaag aatacctaga
     1201 actatttttg caattttagc aggttctagt cttgccataa gcggtgtatt gatgcaatca
     1261 gttactagaa acccaatagc tgatccaggt atactcggta taaacacagg agcaagtctt
     1321 agtgtagtaa ttggtctttc ttttttagga atttcatcaa gcataagcca tataagtttt
     1381 gcaatcattg gtggcttagt aagtgcaatt tttgtatacg cgattgctgt aagcggaaaa
     1441 gcaggcctta cccctataaa acttgcctta tcaggaactt gtgttagtat ggctttaagc
     1501 agttttgtaa gttttttaat tttaccgaat aataacgtct tagacaaatt tagattttgg
     1561 caaataggta gccttggagc agctacatta tcttctatat ctacactact accttttata
     1621 attttaggtc acttgatagc tatatttatt tcatcagatt taaacgcttt agctatgggt
     1681 gatgaaatgg ctgttggtct tggagttaat gttaatagga taagatcact tgcaataatt
     1741 gcaagtgtgc ttttatgttc aagtattact gcaattggtg gacctattgg cttcgtaggt
     1801 cttatagttc ctcacttttg tggcttattt ataagcaaag atatacgcac aatgaccatt
     1861 tcttcatctt ttataggtgc agagctcttg cttatatgtg atataatcgg ccgtatgtta
     1921 ggtaaaccag gtgaaattga agtagggata attactgcaa taatcggggg tccagtactt
     1981 atttatgtaa ctatgaaaaa tagaggggtt aataactaat gcaaaattta attataggta
     2041 ttcaaaaaag aaaaaataga ataacactat tctcctcact atttttatta ataataatca
     2101 gtctatcatt tttcatttta cttatcggag atgaaagtta ttctttttca actttgatta
     2161 aagtcttaaa tagtgaaact gttcctggag ctagtttttc gattatggaa attagattac
     2221 caaaattatt agcaggaatt atagctggct ggtcttttgg attggcagga tttatctttc
     2281 aaactatgtt aagaaatcct cttgcaagtc ctgatataat cggtgtcaca agttcttcat
     2341 ctattgcagc ggtcttttgc atattggtat taaaaacaaa tagtttaact actggaatta
     2401 tttcaataac ttgtggacta acatcatctt taatattatt tttactagct aaaaaagatg
     2461 gtttttcagc agcaagactg ataatattag gtattggttt tcaagctgtc acaagagcag
     2521 gcacctcatt tttattgttg aaagtagcaa gatatgaatt acaagaagtt atgagatggc
     2581 tcagtggctc tttatctttt acaaagttag atgacatacc tcttgttcta atagtaagta
     2641 ttattgctac tatattagtt ttatttttta ataaaagact agaaattatt gaacttggtg
     2701 aagaaatagc aatcggactt ggagcaaatc ccgagctttc aaggcttgtt ttaatttttt
     2761 gcgctgtatc tttaactgct ttttctactt caattacagg accaatagct tgtatatctt
     2821 ttttagctgg tcccatagcc ttaaatattg gcaagaaaag aagcccaata ttagctggat
     2881 tggttggaat tttactagtt ttgttatcag acatattctc tcaaaatatt ttaccagcta
     2941 gatatccagt aggtgttgta actggcttgt taggttcacc atacttaata tacttactaa
     3001 taaaaatgaa caggagaaat atataatgaa aggtctgtgg tcaaataatc ttacctgcgg
     3061 ttatgatgaa aaaataatct tggaaaatat aaatataaaa atacctgaag aaaaaatatc
     3121 agttattatt gggtcaaatg gttgtgggaa atcaacactc attaaaacct tgtctcgact
     3181 tataaagcca ttagagggag aagtattgct tgataataaa tcaattaatt cttataaaga
     3241 aaaagattta gcaaaacaca tagctatatt acctcaatct ccaataatcc ctgaatcaat
     3301 aacagtagct gatcttgtaa gccgtggtcg tttcccctac agaaagcctt ttaagagtct
     3361 tggaaaagat gaccttgaaa taataaacag atcaatggtt atggccaatg ttgaagatct
     3421 agcaaataac ctagttgaag aactttctgg gggtcaaagg caaagagtat ggatagctct
     3481 agccctagcc caagatacaa gtatcctact tttagatgag ccaactactt acttggatat
     3541 ctcatatcaa atagaactat tagacctctt gactgatcta aaccaaaaat ataagacaac
     3601 catttgcatg attttgcacg atataaatct aacagcaaga tacgctgatt acctatttgc
     3661 aattaaagaa ggtaaacttg ttgcagaggg aaagcctgaa gatatactaa atgataaact
     3721 agttaaagat atctttaatc ttgaagcaaa aattatacgt gaccctattt ccaattcgcc
     3781 tctaatgatt cctattggca agcaccatgt tagctcttaa taattgaata ttggaattca
     3841 tttaaaagtc gcaaattttg aactgaccct caaaagttag gccaaaaaac taactaaagg
     3901 aggtcagttt tttaatggca aatacagcac agaatttaag ataaaattag taaaagaata
     3961 tcatgaatga aaaataggat atagagaata acagcaatat taaaaagatc aggactgata
     4021 ataaacaaaa agaaagtaca acgactagtt caaaagctaa aacttcaagt aaaaagttat
     4081 tcaagaaaat ctagaaaata ctcatcctac aaaggacagg taggaaaaat atcagacaac
     4141 aaaataaaaa gaaatattta ttaccgaaaa aaaggggaaa tcgagtcaag taccaacagg
     4201 ctcatctatt ccaaaaagat atttactcga tggaaaaact cctagaatta gtgttacaaa
     4261 tattgacaat ggtatctta
//
LOCUS       DAVMAH010000085         4194 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVMAH010000085 DAVMAH010000000
VERSION     DAVMAH010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4194
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.086"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..255
                     /locus_tag="VYO94_001955"
     CDS             <1..255
                     /locus_tag="VYO94_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760526.1"
                     /translation="LIFLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIVYLF
                     LGYLLVIQKAGYLFSVLLLFSNFSVPFIKEKEFELFKNSK"
     gene            1387..1626
                     /locus_tag="VYO94_001956"
     CDS             1387..1626
                     /locus_tag="VYO94_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760527.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLHKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            2182..4095
                     /gene="pspA"
                     /locus_tag="VYO94_001957"
     CDS             2182..4095
                     /gene="pspA"
                     /locus_tag="VYO94_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEV1760528.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTFVRAEESPQAVEKSSSE
                     KKYDEAKAKSDAAKKNYDEAKKKAAEAQKKYEDDQKRTEEKGALEEETSRKVNDATLE
                     VQNAYVEYGEANKKKAEEAKAEEAVAKEKSDKAAKEVEVAKKRVEAEEAELDKKVAEL
                     QNKVADLEKEIADAEKTVADLEKEVAKLEKDVEDFKNSNGEQAEQYLAAAEKDLVAKK
                     AELAEAKIKAATKKAELEKAEAELENLLSTLDPEGKTQDELDKEAAEAELNKKVEALQ
                     NQVAELEEELSKLEDNLKDAETNNVEDYIKEGLEEAIATKQAELEKTQKELDAALNEL
                     GPDGDEEETPAPAPKPEQPAEQPKPAPAPQPAPAPKPEKTDDQQAEEDYARRSEEEYN
                     RLPQQQPPKAKKPAPAPKPEQPVPAPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWY
                     YLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGWLQYNDS
                     WYYLNANGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGWAKVN
                     GSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTT
                     VDGYKVNANGEWV"
BASE COUNT         1499 a          634 c          851 g         1210 t
ORIGIN      
        1 cttatctttt tgataaaaat ttgtgtagat actacgataa aatttttatt catcagatta
       61 tttgacacaa gtactttaat gaagaggaga atattttttc ttttcgcatt ggatgttata
      121 gtttacttat ttttaggata tcttttagtg attcaaaaag caggctattt gttttcggtt
      181 ttacttcttt tttctaattt ttcagttcca tttatcaaag aaaaggaatt cgaattattt
      241 aaaaatagca agtaatagaa acataggtta aatcttagaa cggcttaaaa tcagatatga
      301 taaagggaaa tagtcttatc taggtaacta agtgctacaa acacagtcga ggatcacttg
      361 ttaggattac attttaatca tgcttaataa gaatggagaa ttcctatggg gattgtatta
      421 ctctgaactt tcgaatacct tagttctcgt gattttgagc tattctagct ttagaatcct
      481 tcagaatgta aaattttaag cagtcaaaga cttagaatag tccggaaaca tttattttat
      541 agcaattcta ggcttagaat tgctcatata tatgtatttg agctgctcga tagttaggac
      601 agctctattc tgagaaatct gagctatcaa tgcttcagaa tagtatttcg ccaatggttt
      661 ttattgaaga ggtgattgtt ttatgatagt ctaaaataaa actgatttaa tggagtaaat
      721 ggagaatcgt tacatgaaac atttttttgc aggaattggt gagataaaac ttgttggcta
      781 cttattgtat atatgtgtag gactagcccc tctttttcat atatatgtca taggttcgga
      841 actgagtttt gtgaaaatag tgttatctat tttgggagtt atatttgtaa gtatgttaac
      901 tattgctcga atttatcgga cttttctata aagaatagtt tggacttgaa ctgtatctaa
      961 aaacagaggt tggtagatta tcagcctctt tcttgtcgtt gaaaagagtg agatatattg
     1021 acttttgaaa aaaatgtcat aattgagttg ggataaacct aaaagtaata tagtagattg
     1081 aatctggaat agtccgttat gactgttaaa atatttctag aaattaattt gactttccta
     1141 atcgatttgt tcacatcttg tttcaatcta ctatactttc tcgttaaacc gttcggtaat
     1201 tcatggtgac atggacacat agtagtaagc acactatgtg gcttggcaga tctaaaaact
     1261 gttcccttgc gataagccta ataagcacaa catagggagt tagagaagcc gactctaatc
     1321 aaccactttg ggcagtagtg gtaactgccc cgtgcttttt attttgagaa aatatggagt
     1381 ttgtcgttga aattacttga ttgtattttg gattatcaag aaagattcaa tggaaaaaca
     1441 tgtcaagtat caacgaatta taagtattta gagattttca aagtgaattt ttgcttgact
     1501 gatttacatc atttatttga cttacacaaa atcacacgag attatgctag tcaaacaaaa
     1561 cctgctattc aagatggtgt ttttatttta gaagatttta gaaatatcct atgtacaatg
     1621 atgtaatcga aaggatatct ttatgtgagt ttatcggcga tatcttctat atctaagcta
     1681 gcaagttgtt gcatcgtagc taaggattta tctaaaaata ctatgaaatt ggacgtcata
     1741 ttttttgagg ataaaaataa aagatccgca gttttaggtt tacgaagaga caaaagcgga
     1801 gtatttaaac cagttactct acattttaca agcgctaaga aatatgctaa agttcgtaaa
     1861 acagatgtga aagaaatgaa atggctataa agattgtccg caggcttaag cttgcgtttt
     1921 ttgttgttta acgaaattaa aaaacaagct ctctcatcgg aaatgttttt ataggaatga
     1981 aggaagatga tgctatgttt aaaaagagaa tcgaaaaggg caaaagtagt atctttatct
     2041 attttttgga gtagaagctt atgatataga aatttgtaat aaaaatgtaa tataaaacat
     2101 ttgacaaata tttacggggg gagtatactt aatataagta tagtctaaaa atgactatca
     2161 gaaaagaggt aaataattta gatgaataag aaaaaaatga ttttaacaag tctagccagc
     2221 gtcgctatct taggggctgg ttttgttgcg tctcagccta cttttgtaag agcagaagaa
     2281 tctccacaag ctgttgagaa atcttcatca gagaagaaat atgatgaagc aaaagcaaaa
     2341 tctgacgctg ctaagaagaa ttacgacgaa gctaaaaaga aagcagcaga agctcagaaa
     2401 aagtatgaag atgatcagaa gagaactgag gagaaaggcg cgctagaaga agaaacttct
     2461 aggaaggtaa acgatgctac tttagaggta caaaacgcat atgtagaata tggagaagct
     2521 aataagaaaa aagcagaaga agctaaagca gaagaggcag tggctaagga aaaatctgat
     2581 aaggcagcta aagaggtaga agtagcgaaa aaaagagtag aggcagaaga agctgagttg
     2641 gataaaaaag ttgctgaact tcaaaataaa gttgctgatt tagaaaaaga aatagctgat
     2701 gctgaaaaaa cggtagcaga tttagaaaaa gaagttgcta aacttgaaaa agatgtagaa
     2761 gatttcaaaa actcaaacgg tgagcaagct gaacaatacc ttgctgcagc tgaaaaagac
     2821 ttagttgcta aaaaagctga attagcagaa gctaaaatta aagctgctac taaaaaagct
     2881 gaattagaaa aagcagaagc tgaacttgaa aacctattat ctacactaga ccctgaaggt
     2941 aagactcagg atgaattaga taaagaagct gctgaagctg agttgaataa aaaagttgaa
     3001 gctcttcaaa accaagttgc tgaattagaa gaagaacttt caaaacttga agataatctt
     3061 aaagatgctg aaacaaacaa cgttgaagac tacattaaag aaggtttaga agaagctatc
     3121 gcgactaaac aagctgagtt agaaaaaact caaaaagagt tagatgcagc tcttaatgag
     3181 ttaggtcctg acggtgatga agaagaaact ccagctccag caccaaaacc agagcaacca
     3241 gctgaacaac caaaaccagc gccggctcct caaccagctc cagcaccaaa accagaaaaa
     3301 acagatgatc aacaagctga agaagactat gctcgtagat cagaagaaga atataaccgc
     3361 ttgccccaac agcaaccgcc aaaagcaaaa aaaccagctc cagcaccaaa accagagcaa
     3421 ccagttcctg caccaaaaac aggttggaaa caagaaaacg gtatgtggta cttctacaat
     3481 actgatggtt caatggctac aggttggctc caaaacaacg gttcatggta ttacctcaac
     3541 agcaatggcg ctatggctac aggttggctc caatacaatg gttcatggta ttacctaaac
     3601 gctaacggcg ctatggctac aggttgggct aaagtcaacg gttcatggta ctacctcaac
     3661 gctaatggtg ctatggctac aggttggctc caatacaacg attcatggta ttacctaaac
     3721 gctaacggcg ctatggcgac aggatggctc caatacaacg gttcatggta ctacctcaac
     3781 gctaacggtg ctatggctac aggttgggct aaagtcaacg gttcatggta ctacctcaac
     3841 gctaatggtg ctatggctac aggttgggct aaagtcaacg gttcatggta ctacctcaac
     3901 gctaacggtt caatggcaac aggttgggtg aaagatggag atacctggta ctatcttgaa
     3961 gcatcaggtg ctatgaaagc aagccaatgg ttcaaagtat cagataaatg gtactatgtc
     4021 aatggtttag gtgcccttgc agtcaacaca actgtagatg gctataaagt caatgccaat
     4081 ggtgaatggg tttaagccga ttaaattaaa tcatgttaag aacatttgac attttaattt
     4141 tgaaacaaag ataaggttcg attgaataga tttatgttcg tattctttag gtac
//
LOCUS       DAVMAH010000086         4126 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVMAH010000086 DAVMAH010000000
VERSION     DAVMAH010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4126
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.087"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            1..286
                     /locus_tag="VYO94_001958"
                     /pseudo
     CDS             1..286
                     /locus_tag="VYO94_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822207.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            214..666
                     /locus_tag="VYO94_001959"
     CDS             214..666
                     /locus_tag="VYO94_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760529.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKARRQIILATHNATIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            1485..1844
                     /locus_tag="VYO94_001960"
     CDS             1485..1844
                     /locus_tag="VYO94_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760530.1"
                     /translation="MSGQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSSFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            1854..2219
                     /locus_tag="VYO94_001961"
     CDS             1854..2219
                     /locus_tag="VYO94_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV1760531.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIDKSHCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSRLISQEQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSH"
     gene            2206..4056
                     /locus_tag="VYO94_001962"
                     /pseudo
     CDS             2206..4056
                     /locus_tag="VYO94_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863411.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
BASE COUNT         1518 a          601 c          821 g         1186 t
ORIGIN      
        1 caagaatcat gggttaatca atgattaagt gaaaatatta taagtgagaa agatggaagt
       61 tatcaacatt cactgactat aatgaaggat ttcaataatc aaaaaatagt taactatatt
      121 gctcatttca atagttatga cattttgaaa aaaggttctc acttatcagg tgcatataaa
      181 cgaaaaattt tttctaaaga aaatacacga tttttggagt ttaatattaa ctcgaaagaa
      241 tcttcgcaac aacttgatat tctctataaa gaagttggtg tattaagttt gggacaaaaa
      301 gttgtagcca tgcttgattt tttattagca tatagtgact attctaaaga cttcagacca
      361 ttgattattg atcagcctga agacaatcta gacaatcgtt atatttacag gcatttagtt
      421 cagcagttta gagatgtgaa agctcgacgt caaattattt tagcaacaca taatgctaca
      481 attgtaacaa attctatgac agatcaagtt gttattatgg agtcagatgg agttaacgga
      541 tggattgaat cacagggata tgttagtgaa aaatatataa aaaatcatat catcaatcaa
      601 ttagagggag gaaaagattc cttcaagcat aaaatgtcta tatatgagac ggctttatca
      661 gagtagagtc agaaaaagta ggttagaaat ttagcctact tttttctttg ttcgacaggc
      721 atagtgtaca tctgaggtcc aagtcctctg tggatatttg ctgcagatga aaccaatagc
      781 gactcctaaa cctgaatatc gtgaggtagg ggggatagga aggaattagc gaaatcaagg
      841 ttctacaaac agaatcgtga cttgaagcca tatatagcgg atgaggaact ctaaaatcca
      901 aataggtgtc gtaacctata tacgtaaatt acgagagtaa actaggaaag atgtacggct
      961 tattccgtga gcgtttagga cgtagtacaa caaatcatgg gagtcagctg aacacatagt
     1021 attgaagaaa tttctgtaat ggaaatggag cgaagaagtg aacaattaaa tgaatacctc
     1081 tctaattaaa tttgtcaatt ctaattcctg gtatgaaaag acagtgacct aaaaatgtaa
     1141 acgatgggag ctgattataa atataggacg gtacatgcag tggtgttaga gattagtccc
     1201 tacttgattt gtgataactt ccccaacttt cttctgctat acttttctca acttttaaaa
     1261 atccaactaa gaattttacc tgggagtttg ggggcgtagc caccaagtta tcttatggtt
     1321 agctgtcaaa actggaaggt tttggttagc tggcgatatg attttttggg tattgtgacc
     1381 acaatgcctg agctcgcaaa gaccgaacaa ggactttaag aaatttcccg tatgacacac
     1441 ggggtcgggg tttacccgag aaaggatgaa agtgaggaaa agagatgtct ggacagtacc
     1501 gtgacattcg aaaagaggta aatctaaccg cagatgagct aaaacagatt gaaaaaatga
     1561 tggaggttga taattatcgt cacttttcat cattcgtcag ggataaaatt ttgatgactg
     1621 atgacaaaca gttagctgcc aaagaatggt tttccctttg gcagtctcaa aagtttgaac
     1681 agatcagtcg agatgtgcat ttggttttga ttatcgcaag agagaatcac caagtgactc
     1741 aagaacacgt gtcaatctta ttgacctgcg ttcaagaatt gattgcggaa gtcaatcaag
     1801 tacagtcact cagtcgtggg tttcgtgaaa aatacatgag ataggaggct actatggttt
     1861 atcgttatcg taccaatctc aaaaaagtat ttctaacaga ttcagaatta catcaattga
     1921 atgagcgaat cgataagagt cactgtcaaa atttttcagt ctatgccagg aaagtgttgc
     1981 tgaatcccaa tatgtcattt gtcaccatta atacggatac ctatgaccag ttagtatttg
     2041 aattgagacg gatcggaaat aacattaatc aaattgcgcg tgctatcaat caaagccgtc
     2101 tgatttctca ggaacagtta caagaattga gtaaaggagt cggagagttg atcaaggaag
     2161 tggacaaaga atttcaagtg gaagtgaaaa gattgaagga gtttcatggt agtcactaag
     2221 cattttgcga cacacggaaa aaaatatcgt aggcgtttaa ttaagtatat cctcaatcct
     2281 gataaaacgg acaatttgaa attagtatct gattttggta tgagcaatta cttagacttt
     2341 cctagctatg aagaaatggt agaaatgtac aatgtcaact ttaccaataa tgacaagttg
     2401 tacgaataca gaaatgaccg acaagaaaaa caccaacaaa atattcatgc ccatcacctc
     2461 attcaatcat tttctcctga agataatctg acacctgaag aaattaaccg cattggttat
     2521 gagaccatta tggaattaac aggaggccgt tttcgtttca tcgtagcgac tcatacagac
     2581 aaagatcata ttcataatca catcttaatc aacgccattg actgtaattc agataaaaag
     2641 ttgatatgga actatgctat agaaagaaat tttcgtatga tttcagaccg tatttctaaa
     2701 gtggctggtg caaaaattat tgagaaacgt tattcctacc gagattataa aaaatatagg
     2761 gaatctagtc ataagtttga attgaaacaa cgtctttatt ttttgctaca gcaatctaaa
     2821 tcgtttgatg attttttaga gaaagcaaag cagttgcatg ttcagattga ttttagtcaa
     2881 aagcatagcc gttttttgat gacagataga acgatgacaa aaccgattcg agggcgctaa
     2941 ctcagcaaac gagatcgata tgatgaagaa ttttttagaa cgcattttgc taagcaagag
     3001 attgaaagtc gtttagaatt tttgttgaac cgtgttaatt ctttagaaga gttaataaca
     3061 aaagcaaaag aattgaatct aaccattgac ttaaaacaaa aaaatgtaac ttttatcctg
     3121 gaagaaaata atcaaaagat aagtttgggt catcaaaaaa taagtgataa gaaattatat
     3181 gatgtcaaat tttttcaaga ttattttaaa aataaggaag tcgttgcttc agaaggatta
     3241 gagaatttac gggaacagta ccatgctttc caagaagaac gagataagga taaagtatcc
     3301 actgaagaga ttgaggaagc ctttaagaca tttaaggaaa aatgagatac cgttcgtgaa
     3361 tttgaagtgg aacttgcaga gaaccaaata gagaagctag ttgatgaggg aatttatatc
     3421 aaagtgtctt ttggtattaa gcagagtggt cttattttca ttcccaatta tcaattggat
     3481 actatggaag aagacaatca gaaaaaatat aaagtctaca tccgtgagac aaccttatac
     3541 tttgtctata acaaagaaca ttcggataaa aatcagtata tcaaaggtcg aaccttgatt
     3601 aggcagttaa ctaatgatag tcgagtgata ccatacagaa gacctacagt taagagtcta
     3661 caggaaaaga ttactgagat taacctcttc attgaattaa ctgaagcaga taagaaatac
     3721 caagacatta aagacgagtt agtaaaagaa atagcagaga tagatataaa actaaatcaa
     3781 attaatgaaa aaatcgtcaa tttaaataag atggcggaag tgtttatcaa tctaaagagt
     3841 gaagatgcga gcagccaaaa attagccagg tatgactttt caaaactgaa cttaacagaa
     3901 tcaacttcat tagaaaatgt gaacgaagaa ataagagtat tgcaagaaaa cttagactat
     3961 tatctttatg agtttgagaa aagagcaata agattagaaa tttttgtaag cacgttaaat
     4021 atggaaaaag atgttttcgt aattgacaaa ttttagagga gggataaagc tagaaatgct
     4081 ggattatgct tgatttaagg aactgcaata catggagcac actcat
//
LOCUS       DAVMAH010000087         4076 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVMAH010000087 DAVMAH010000000
VERSION     DAVMAH010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4076
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.088"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(555..1547)
                     /locus_tag="VYO94_001963"
     CDS             complement(555..1547)
                     /locus_tag="VYO94_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1760532.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            1707..3461
                     /locus_tag="VYO94_001964"
     CDS             1707..3461
                     /locus_tag="VYO94_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760533.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     TLLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSICDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            3427..>4076
                     /locus_tag="VYO94_001965"
     CDS             3427..>4076
                     /locus_tag="VYO94_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760534.1"
                     /translation="MNGGFQMKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAI
                     LLMIFAQEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTA
                     ENLSKLPLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAG
                     NVKMGLAVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKA"
BASE COUNT         1440 a          596 c          656 g         1384 t
ORIGIN      
        1 aatcgaaaaa tggttaagta aaagtcaaca gttactatag tttgcaaatt atttacagaa
       61 agaacaaaaa atgctctgaa acactgattt caaagcattt tttgttagtt taaaattact
      121 cccattcttc ttttccaaac gtacaatata tccaaaacca ttcaaaatac tagattctat
      181 tttttataat atcactaaat ccacctaatt ataggacgtt ttcagatttt tagtcccgtc
      241 ccagtcccag taccggagaa atattgtttt aatataatat ctctttttgt cttctaagct
      301 cttaaaagca aaagaacaag taaagagtca agacaaggat aaaaagtcca tattagggca
      361 aataaaaagc tttaagacag atgacaaatc taagtcaaat aagaaagacc atagcaaagg
      421 tgcagagaga taaatattgg cggtcttcgg actgccttta tttttttatc catttttcaa
      481 atcaaattta ttcagactat atatgcacat atacacttaa attcatataa aaacatggct
      541 tgtaaaaaat tactttaatc acaataatcg catttaaaat tgtgatgttt gcaagctaaa
      601 ttacggactt cacttggaag ttttcccttg tatcttttat aatagataga aaatttgctg
      661 gcagatgaat atccaacaga ttctgctatc tcttttatag gtagttcagt gtttaaaaga
      721 agagtttcag ctacattcat tctttttctt tgagtgtact ctgtaatgct ttgacaatat
      781 ttttccttaa ataaattttt taatttagta ccactcattt tagatatttt ttcaagcgtg
      841 ccttgattta cattcgttgc aaaatgatca tctaagaatc ttgctacatc ttcaagtgct
      901 ttatcatcat caatttcaat tttatatttt tttctattta agtatgtgtc aattactata
      961 cttatccatt catttgcctt tgctttaaag aaaaaatcag cggcaggagc gtccatctta
     1021 caatttaata tttccattgc cactctttct aaggcctttg taagtattat ttgattcggt
     1081 tgaagcaagg ttgaataaaa agattctgga ttaatgttaa tagatgctaa atgtttttct
     1141 attagctctt ttttaaaacc aatggaaaca gcaagataac aacaattctc gtgtaataaa
     1201 aaaacaaaat catcttttat attatcaaaa tcaaaagtac ataaagagtt tgcggtaata
     1261 gtttgatacg gattaaactt ttctccgttt gcactgacaa tgtaacttga ataaattgaa
     1321 acatagtctg acatactata agtgctattt tgaactactt cctctttgat ataaaaatca
     1381 tgtatatcga taatgaagct gcctccttca taaaaccaat ataggccttc tgcataagtt
     1441 gaattctctt ttttccaaca aaatgtatga cctgcacttg aatacttctc attgttttta
     1501 cattcatcta ctttcatata atcttttaca aaatcataat atgacataac atactatccc
     1561 ttttagacaa tattccaatt agccttatta attcaaaact attgtattag taattataac
     1621 agatgtataa tagaaaagca atgatagata ttatcaattc agcgaattta tatctaaaag
     1681 ggatattaaa gaaaggagat atgcttatga agatttacaa aaaactattt gcttatgtcc
     1741 aagataagaa atatcttggg gttttggcca taattttttc tgctatatct gctgcactta
     1801 cagtatatgg atattattta atctacaaat ttctagataa gttaataatt aattcaaact
     1861 tatccggtgc agagagtata gcattaaaat ctgttattac actaacaagt ggagcgatat
     1921 tttattttgt ctcaggaatg ttttcacata tcttgggatt taggcttgaa acaaatttaa
     1981 gaaaaagggg aatcgatggt ctggaaaaag caagttttag gttctttgac ttaaatccat
     2041 ctggtcaaat aagaaagatc atagatgata atgcagcaca aactcatcag gtggtagctc
     2101 acatgattcc agatagctct caggcaatag tcacacctat acttgtcctt gtactaggct
     2161 ttatagtaag tataagggtt ggtataactt tgcttgctct tactataatt ggcggcttaa
     2221 ttttaggggc aatgatgggc gagcaagaat ttatgaagat ataccaagaa tccctatcta
     2281 aactaagtgc tgaaactgtt gagtacgtga gaggaatgca agttgtaaaa atatttaaag
     2341 caaatgtaga gtcatttaaa agcttttaca aggctataaa agattactca aagtatgctt
     2401 atgattattc cctatcttgt aaaaggcctt atgttttgta tcaatggtta ttttttggac
     2461 tgattgcaat tttaattatt cctatagttt attttatgac tagcttagct agcgcaaagg
     2521 tgattttact tgagcttatc atgattttat ttttatcagg agttctcttt gtttcattca
     2581 tgagaatgat gtggtactcc atgtatattt ctcaaggaaa ttatgcagta gatactttag
     2641 aggcgcttta cgaagatatg caaaaagaca aattagtgca tggtaatgtc aataatttta
     2701 aaaactataa tatagaattt gagaatgtta gctttgctta taatgataaa gctgtcattg
     2761 aaaatttatc ctttaattta gaagaaggaa agtcctacgc acttgtcggt tcatctggat
     2821 caggcaaatc aacagtagca aaacttatat caggttttta caatgttaat aaaggaagca
     2881 taaagatagg cgggatagca ataagtgaat attctgacga agccttaatt aaagccattt
     2941 cctttgtttt tcaagattca aaattattta agaagagcat ttgtgataat gtagctttag
     3001 ctaataaaga tgcgacgaaa gatgacgtta tgagagcctt aaaattagca ggatgcgatt
     3061 taatattaga caaattccca gaaagagaaa atacaatcat aggctcaaaa ggtgtttatt
     3121 tatccggtgg agaaaaacaa agaattgcaa ttgctagagc aattttaaag gattccaaaa
     3181 ttattattat ggatgaagca tcagcatcta ttgacccaga taacgagttt gaattgcaaa
     3241 aagcttttaa aaatcttatg aaggataaaa cagttatcat gattgcacac aggctatcta
     3301 caattaaaga ccttgatgaa attattgtca tggatagtgg aaaaattata gaaagagggt
     3361 ctgacaaaga attaatgtca aaagatacaa ggtataagag cctgcaagag atgtttaaca
     3421 gtgcgaatga atggagggtt tcaaatgaaa gagttttata aaaaaagatt tgctcttaca
     3481 gatggaggag caagaaattt aagtaaagca acactggctt catttttcgt ttattgtata
     3541 aacatgcttc ctgccatatt acttatgatt tttgctcagg aagttttgga aaatatgggc
     3601 aaaagcaatg gcttttatat agtattctca gttttgactt tgatagcaat gtatattttg
     3661 ctttctatcg aatacgataa attatataac acaacctatc aagaaagtgc agatttaaga
     3721 ataaggacag cggagaattt atcaaaatta cctctatctt acttttctaa acatgacatt
     3781 tccgacattt cacaaacaat catggctgat attgaaggca tagagcatgc aatgagccac
     3841 tcaataccaa aggtgggcgg catggtactg tttttcccat taatatctgt aatgatgcta
     3901 gcgggcaatg tcaagatggg tttagctgta attattccat ctattttaag ctttatattt
     3961 atacctttat ctaaaaaata tcaggttaat ggacagaata gatattatga tgtcttaaga
     4021 aaaaactcag aaagctttca agaaaatatc gaaatgcaaa tggagattaa agcata
//
LOCUS       DAVMAH010000088         4041 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVMAH010000088 DAVMAH010000000
VERSION     DAVMAH010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4041
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.089"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            62..859
                     /locus_tag="VYO94_001966"
     CDS             62..859
                     /locus_tag="VYO94_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV1760535.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSLLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1007..2266
                     /locus_tag="VYO94_001967"
                     /pseudo
     CDS             1007..2266
                     /locus_tag="VYO94_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2362..3636
                     /locus_tag="VYO94_001968"
     CDS             2362..3636
                     /locus_tag="VYO94_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV1760536.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QLLENQLATLHLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3648..>4041
                     /locus_tag="VYO94_001969"
     CDS             3648..>4041
                     /locus_tag="VYO94_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760537.1"
                     /translation="MEDDLNYENLMDDVTEAIKKFNLVIFIGAGVSIAQGYPNWNNYI
                     EHLIKYWQGQVLSVSGEKRLGREHHVVFDLISKSSISNKRKVDLVNYELKKVFGEDFE
                     KRRLDFEKGYFKNLLPYSIVNQTVESLAS"
BASE COUNT         1258 a          708 c          874 g         1201 t
ORIGIN      
        1 cgcttcctaa aacctaaagt ttgtgatata attatcaaga aaaaagattt aggagtttat
       61 tatggtttct tcagaattta tctcaaagat tgaatttgct tgcaataaga aagaaagtct
      121 ttatagtcaa agcaaattta agtatgcgat tcgttcgatg ttcgcaggtg catttttaac
      181 cttcagtact gctgcaggtg cagttggggc tgacttgatt aataaaattg caccaggtag
      241 tggacgcttc ctctttccat tcgtttttgc ttggggcttg gcctacattg tttttttgaa
      301 tgccgagttg gtcacttcaa acatgatgtt cttgactgct ggtagtttat taaaaaaaat
      361 ctcttggaga aaaacagctg agattttact atactgtacc ttgttcaacc ttatcggagc
      421 cttgatagca gggtggggct ttgctcattc ggcagcctat gcgaatctga cacacgatag
      481 tttcatctca ggtgttgttg agatgaagtt aggccgctca aatgaattgg tcttgcttga
      541 ggcgattttg gcaaatattt tcgtaaatat tgcgattctg tcatttattt tggtcaaaga
      601 tggtggtgcc aaactttggc ttgtgttgtc agctatttac atgtttgtat tcttaacaaa
      661 cgagcacatt gcggcgaact ttgcttcttt cgcgattgtg aaattcagtg ttgctgcgga
      721 ttcaattgcc aacttcggtg ttggaaatat gcttcgccac tggggtgtga ctttcatcgg
      781 aaactttatc ggaggaggcc tcttgatggg tcttccatat gccttcctca ataaaaacga
      841 agatacttat gtagattaag aaaatgagca cgattgagtc gtgctttttt cattttcaaa
      901 ataaggtaat agctatttct tatatcaaaa tatagaaaac tgatatttgt aaactataac
      961 tcaaggtgct acaatatcct taataaaatg atatggaggt caccttatga cttgtgattt
     1021 taaatctgaa actctacaac tacatgctgg tcaagttgcg gctccagcta ctaagtctcg
     1081 tgcagtgccg atttatcaaa caacattttt tgtttttgat gacacgtagg aaggtgccga
     1141 tctgtttgcc ttgaggaaac cagggaacat ttatactcgt atcaccaatc ctacaacagc
     1201 tgcccttgaa ggtggtgttg aagcgctagc aacagcatca ggtatgactg cagtgactta
     1261 tacgattttg gcgcttgccc atgctggtga ccatgtagtg gctgcttcga ctatttacgg
     1321 tggaaccttc aatcttttga aagaacccct tcctcgttat ggtatcacaa caacctttgt
     1381 cgatgttgat aatttggagg aagtagaagc agctatcaaa gacaatacca agcttgtctt
     1441 gattgaaacc ttgggtaact ccttgattaa tattccagac ctggaaaaac tggcagagat
     1501 tgctcataaa catcaaatcc cacttgtgtc agacaatact tttgcaatac cttatttgat
     1561 taacgtcttc tctcatggcg ttgacattgc cattcactct gcgactaagt ttatcggtgg
     1621 gcatggtaca actattggag gaataattgt cgatagtggt cgttttgact ggatggcttc
     1681 agggaaattc cctcaatttg ttgacgaggg ttcaagctgc cacaatttga gctatactcg
     1741 tgatgtgggt gcagtagcct ttattatagc tgttcgagtt caattgcttc gtgatacagg
     1801 tgcagccttg tcaccattca atgctttcct cttgctacaa agacttgaaa ccctttcact
     1861 tcgtgtggaa cgccatgtac aaaatgctga gacaattgtt gattttcttg tcaaccatcc
     1921 taaggtagaa aaggtaaatt atccaaaact tgcagatagt ccttatcatg cattggctga
     1981 gaaatacttg ccaaaaggtg tcggttcaat ctttaccttc cacgtcaaag gtgacgagga
     2041 agaagcacgc aaggtcattg ataatttaga aatcttttct gaccttgcaa acgcggcaga
     2101 tgctaaatcg cttgttgtcc atccagcaac aatcactcac ggtcaattgt cagaaaaaga
     2161 cctagaagca gcaggtgtca caccaaatca aatccacttg tctatcggtc ttgaaaatgt
     2221 agaagatttg attgaagact tacgcttggc cttggaaaaa atttaaagta aaagaagata
     2281 aacagtgggt tttgactcac tgtttttgat tttccttcat gcatgatata atggttacag
     2341 aagtctagaa agaggaatgt aatgaacgaa atcaaatgtc ccaactgtgg ggaagtcttt
     2401 acagtaaatg aaagccagta tgctgaactt ttgtcccaag tgagaacggc agagtttgat
     2461 aaggaactac acgataggat gaggcaggaa ctggccttgg ctgagcaaaa ggctatgaat
     2521 gagcaacaga ctaaactggc tcagaaggat caagaaattg cgcaattaca gagtcagatc
     2581 caaaactttg atacagaaaa agaattggcc aagaaagaag ttgaacagac aagccatcag
     2641 gccttattgg ctaaggacaa ggaagtacag ctcttagaaa atcagttggc taccttgcat
     2701 ttggagcatg aaaatcaact acaaaagacc ctttctgacc tagaaaaaga acgggatcag
     2761 gttaaaaacc aactactttt gcaggaaaag gaaaatgaat tatctttggc ttctgttaag
     2821 caaaactacg aagcccagct caaggcagct agtgaacaag tcgagtttta taagaatttt
     2881 aaggctcaac aatctacaaa agcgattggg gaaagcctag aacagtatgc agagagtgag
     2941 tttaacaagg ttcgtagttt cgcctttcca aatgcttact ttgagaagga taacaaggtc
     3001 tcttcgcgtg ggtctaaagg ggactttatc ttccgtgagt gtgatgaaaa tggagttgaa
     3061 atcatttcta tcatgtttga gatgaaaaac gaagcagacg gaacagagaa gaagcacaag
     3121 aatgcagatt tttacaagga attggacaag gaccgtcggg agaagaactg tgagtatgcc
     3181 gttttggtga ccatgcttga ggccgataat gactacttta acacagggat tgttgacgtc
     3241 agccacgagt atgaaaaaat gtatgttgtt cgtcctcaat tctttatcca attgattggt
     3301 ctcttacgta atgcggcgct aaattcccta aaatacaagc aggagttggc cttggttcgc
     3361 gagcaaaata ttgacattac gcattttgag gaagacttgg atgcctttaa gctagctttt
     3421 gctaagaact ataattcagc ttcgactaac tttggaaaag ctattgatga aatcgacaag
     3481 gccatcaaac gcatggaaga ggttaagaaa ttcctgacta catctgaaaa ccaactccgt
     3541 ctagctaaca acaaattgga agatgtctct gttaaaaaat tgacccggaa aaatccaaca
     3601 atgaaagcga agttcgaagc actgaagggg gagtgaggaa ataagttatg gaagatgatc
     3661 ttaattatga aaatttgatg gatgatgtaa ccgaggctat aaaaaagttt aacttagtaa
     3721 tttttattgg cgcaggagtt tcaattgctc aaggttatcc taattggaac aattatattg
     3781 aacatcttat taagtattgg caaggacaag ttttatcggt aagtggtgaa aaaaggcttg
     3841 gaagagaaca tcacgtagtt tttgatttaa ttagcaaatc tagtattagt aataaacgta
     3901 aagtggatct tgtaaactat gaattaaaaa aagtttttgg tgaagatttt gaaaagcgac
     3961 gactagattt tgaaaaagga tattttaaaa atctattacc atattcaata gttaatcaaa
     4021 cagtagaatc tttagcaagt t
//
LOCUS       DAVMAH010000089         3873 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVMAH010000089 DAVMAH010000000
VERSION     DAVMAH010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3873
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.090"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            219..482
                     /locus_tag="VYO94_001970"
     CDS             219..482
                     /locus_tag="VYO94_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV1760538.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            488..2221
                     /gene="ptsP"
                     /locus_tag="VYO94_001971"
     CDS             488..2221
                     /gene="ptsP"
                     /locus_tag="VYO94_001971"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV1760539.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQCEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            2476..>3873
                     /locus_tag="VYO94_001972"
     CDS             2476..>3873
                     /locus_tag="VYO94_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1760540.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAKAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQSTTEPSPSPQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEKNGVSRYIPAKNLSAETAAGIDSKLAKQESLSHKLG
                     TKKTDLPSSDREFYNK"
BASE COUNT         1283 a          757 c          824 g         1009 t
ORIGIN      
        1 tgtgaaatag caatgattat cctataaatt gtttttgaag aaactatatc ctgtgttttg
       61 ttatctagga tagaagattt tcagcaagtt atctgaaagg aaattgaagg aaaatccaga
      121 aaatgcttga aaaaaatcct agaagatggt ataatactaa attgtaaggg ttatcacata
      181 taactcaaaa aaagaaagaa caaaaggaga gtcaaactat ggcttctaaa gatttccacg
      241 tagtggcaga aacaggtatt cacgcacgtc cagcaacatt gttggtacaa actgctagca
      301 aatttgcttc agatatcact cttgagtaca aaggtaaatc agttaacctt aaatcaatta
      361 tgggtgttat gagtcttggt gttggtcaag gtgctgacgt aactatctca gctgaaggtg
      421 cagatgcaga tgacgctatc gctgcaatct cagaaacaat ggaaaaagaa ggattggcat
      481 aagggaaatg acagaaatgc ttaaaggaat cgcagcatct gacggtgttg cagttgcaaa
      541 agcatatcta ctcgttcagc cggatttgtc atttgagact attacagtcg aagatacaaa
      601 cgcagaagaa gctcgccttg atgccgctct acaggcatca caagacgagc tttctgttat
      661 tcgcgagaaa gcagtaggta cgctcggtga agaagcagct caagtttttg atgctcactt
      721 aatggttctt gctgacccag aaatgatcag ccaaatcaag gaaactatcc gtgcgaagaa
      781 agtgaatgca gaagcaggtc tgaaagaagt tacagatatg tttatcacta tctttgaagg
      841 catggaagac aacccataca tgcaagaacg cgcagcggat atccgcgacg tgacaaaacg
      901 tgtattggca aaccttcttg gtaaaaaatt gccaaaccca gcttctatca atgaagaagt
      961 gattgtgatt gcacatgact tgacaccatc tgatacagct caattggaca aaaactttgt
     1021 aaaagctttt gtaaccaaca tcggtggacg tacaagccac tcagctatca tggcacgtac
     1081 acttgaaatt gcagctgtat taggtacaaa caacatcact gaaatcgtta aagacggtga
     1141 catccttgct gttaacggga tcactggtga ggttattatc aacccaactg atgaacaagc
     1201 ggcagaattt aaagcagctg gtgaagctta tgcgaaacaa aaagctgaat gggcgctctt
     1261 gaaagatgct caaacagtga ctgctgacgg taaacacttc gagttggctg ctaatatcgg
     1321 tactccaaaa gacgttgaag gtgttaacaa caacggtgca gaagctgttg gactttaccg
     1381 tacagagttc ttgtacatgg attctcaaga cttcccaact gaagatgagc agtgtgaagc
     1441 atacaaggct gttcttgaag gaatgaacgg taaacctgtt gtcgttcgta caatggatat
     1501 cggtggagat aaggaacttc cttacttcga tatgcctcac gaaatgaacc cattccttgg
     1561 attccgtgct cttcgtatct ctatctctga gactggagat gctatgttcc gcacacaaat
     1621 ccgtgctctt cttcgtgcgt ctgttcacgg tcaattgcgt atcatgttcc caatggttgc
     1681 gctcttgaaa gaattccgtg cagcgaaagc agtctttgat gaagaaaaag caaaccttct
     1741 tgctgaaggt gttgcagttg cggataacat ccaagttggt atcatgatcg agattcctgc
     1801 agcagctatg cttgcagacc aatttgctaa agaagttgac ttcttctcaa ttggtacaaa
     1861 cgacttgatc caatatacaa tggcagcaga ccgtatgaac gaacaagttt cataccttta
     1921 ccaaccatac aacccatcaa tcctacgctt gattaacaat gtgatcaaag cagctcacgc
     1981 tgaaggtaaa tgggctggta tgtgtggtga gatggctggt gaccaacaag ctgttccact
     2041 tcttgtcgga atgggcttgg atgagttctc tatgtcagca acatctgtac ttcgtacacg
     2101 cagcttgatg aagaaactcg acacagctaa gatggaagag tacgcaaacc gtgcccttac
     2161 agaatgctca acaatggaag aagttcttga acttcaaaaa gaatacgtta attttgatta
     2221 atcgaaaagt ccctgcaact cagttacagg gacttttttt gatattttaa aaagaatttt
     2281 caagaaaatc tttcttataa aaagtccaac cttgaaaaag tagtggtcag aacaaaaaat
     2341 acttaaatgg ttcataaaat tcttgacaag ttggagattt aggagtaaac tattaaccag
     2401 ttaagtaata gagaggagtt tctgcaattt agaaatgaat tgcaactaga aatatcaaat
     2461 agaaagagag tttcgatgaa aattaataag aaataccttg ttggttctgc ggcagctttg
     2521 attttaagtg tttgttctta cgagttggga ctgtatcaag ctagaacggt taaggaaaat
     2581 aatcgtgttt cctatataga tggaaaacaa gcgacgcaaa aaacggagaa tttgactcct
     2641 gatgaggtta gcaagcgtga aggaatcaat gctgagcaaa tcgtcatcaa gataacagac
     2701 caaggctatg tcacttcaca tggcgaccac tatcattatt acaatggtaa ggttccttat
     2761 gatgcgattt tcagtgaaga attactcatg aaagatccaa actataagct aaaagatgag
     2821 gatattgtta atgaggtcaa gggtggatat gttatcaagg tagatggaaa atactatgtt
     2881 taccttaagg atgctgccca cgcggataac gtccgtacaa aagaggaaat caatcgacaa
     2941 aaacaagaac atagtcaaca tcgtgaaggt gggactccaa gaaacgatgg tgctgttgcc
     3001 ttggcacgtt cgcaaggacg ctatactaca gatgatggtt atatctttaa tgcttctgat
     3061 atcatagagg atactggtga tgcttatatc gttcctcatg gagatcatta ccattacatt
     3121 cctaagaatg agttatcagc tagcgagttg gctgctgcaa aagccttcct atctggtcgg
     3181 ggaaatctgt caaattcaag aacctatcgc cgacaaaata gcgataacac ttcaagaaca
     3241 aactgggtac cttctgtaag caatccagga actacaaata ctaacacaag caacaacagc
     3301 aacactaaca gtcaagcaag tcaaagtaat gacattgata gtctcttgaa acagctctac
     3361 aaactgcctt tgagtcaacg ccatgtagaa tctgatggcc ttattttcga cccagcgcaa
     3421 atcacaagtc gaaccgccag aggtgtagct gtccctcatg gtaaccatta ccactttatc
     3481 ccttatgaac aaatgtctga attggaagaa cgaattgctc gtattattcc ccttcgttat
     3541 cgttcaaacc attgggtacc agattcaaga ccagaacaac caagtccgca atcgactaca
     3601 gaacctagtc caagtccgca acctgcacca aatcctcaac cagctccaag caatccaatt
     3661 gatgagaaat tggtcaaaga agctgttcga aaagtaggcg atggttatgt ctttgagaag
     3721 aatggagttt ctcgttatat cccagccaag aatctttcag cagaaacagc agcaggcatt
     3781 gatagcaaac tggccaagca ggaaagttta tctcataagc taggaactaa gaaaactgac
     3841 ctcccatcta gtgatcgaga attttacaat aag
//
LOCUS       DAVMAH010000090         3808 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVMAH010000090 DAVMAH010000000
VERSION     DAVMAH010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3808
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.091"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..418
                     /locus_tag="VYO94_001973"
     CDS             <1..418
                     /locus_tag="VYO94_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1760541.1"
                     /translation="KNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDETEIPQVENSVINAKIAEAEALLEKVTDSSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
     gene            628..3741
                     /gene="phtE"
                     /locus_tag="VYO94_001974"
     CDS             628..3741
                     /gene="phtE"
                     /locus_tag="VYO94_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV1760542.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVINLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKLSETGNSTSNS
                     TLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTGEA
                     PQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNKKPVKPENSTDNGMLNPEGN
                     VGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVIKK
                     NLSDLIA"
BASE COUNT         1430 a          622 c          744 g         1012 t
ORIGIN      
        1 taaaaataag gcagaccaag acagtaaacc tgatgaagat aagggacatg atgaagtaag
       61 tgagccaact caccctgaat ctgatgaaaa agagaatcac gctggtttaa atccttcagc
      121 agataatctt tataaaccaa gcactgatac ggaagagaca gaggaagaag ctgaagatac
      181 tacagatgag actgaaattc ctcaagtaga gaattctgtt attaacgcta agatagcaga
      241 ggcggaggcc ttgctagaaa aagtaacaga ttctagtatt agacaaaatg ctatggagac
      301 attgactggt ctaaaaagta gtcttcttct cggaacgaaa gataataaca ctatttcagc
      361 agaagtagat agtctcttgg ctttgttaaa aaaaagtcaa ccggctccga tacagtagta
      421 aaatgaatgg agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa
      481 aaacgtaaca gaaacttgac aaaagtaatt ttaaatagta aactatttac tggttaatta
      541 aatggttaaa taaccggttt agaaaactat ttaataaagt aaaagaagtt gagaaaaaac
      601 ttcatcattt attgaaatga gggatttatg aaatttagta aaaaatatat agcagctgga
      661 tcagctgtta tcgtatcctt gagtctatgt gcctatgcac taaaccagca tcgttcgcag
      721 gaaaataagg acaataatcg tgtctcttat gtggatggca gccagtcaag tcagaaaagt
      781 gaaaacttga caccagacca ggttagccag aaagaaggaa ttcaggctga gcaaattgta
      841 atcaaaatta cagatcaggg ctatgtaacg tcacacggtg accactatca ttactataat
      901 gggaaagttc cttatgatgc cctctttagt gaagaactct tgatgaagga tccaaactat
      961 caacttaaag acgctgatat tgtcaatgaa gtcaagggtg gttatatcat caaggtcgat
     1021 ggaaaatatt atgtctacct gaaagatgca gctcatgctg ataatgttcg aactaaagat
     1081 gaaatcaatc gtcaaaaaca agaacatgtc aaagataatg agaaggttaa ctctaatgtt
     1141 gctgtagcaa ggtctcaggg acgatatacg acaaatgatg gttatgtctt taatccagct
     1201 gatattatcg aagatacggg taatgcttat atcgttcctc atggaggtca ctatcactac
     1261 attcccaaaa gcgatttatc tgctagtgaa ttagcagcag ctaaagcaca tctggctgga
     1321 aaaaatatgc aaccgagtca gttaagctat tcttcaacag ctagtgacaa taacacgcaa
     1381 tctgtagcaa aaggatcaac tagcaagcca gcaaataaat ctgaaaatct ccagagtctt
     1441 ttgaaggaac tctatgattc acctagcgcc caacgttaca gtgaatcaga tggcctggtc
     1501 tttgaccctg ctaagattat cagtcgtaca ccaaatggag ttgcgattcc gcatggcgac
     1561 cattaccact ttattcctta cagcaagctt tctgccttag aagaaaagat tgccagaatg
     1621 gtgcctatca gtggaactgg ttctacagtt tctacaaatg caaaacctaa tgaagtagtg
     1681 tctagtctag gcagtctttc aagcaatcct tcttctttaa cgacaagtaa ggaactctct
     1741 tcagcatctg atggttatat ttttaatcca aaagatatcg ttgaagaaac ggctacagct
     1801 tatattgtaa gacatggtga tcatttccat tacattccaa aatcaaatca aattgggcaa
     1861 ccgactcttc caaacaatag tctagcaaca ccttctccat ctcttccaat caatccagga
     1921 acttcacatg agaaacatga agaagatgga tacggatttg atgctaatcg tattatcgct
     1981 gaagatgaat caggttttgt catgagtcac ggagaccaca atcattattt cttcaagaag
     2041 gacttgacag aagagcaaat taaggctgcg caaaaacatt tagaggaagt taaaactagt
     2101 cataatggat tagattcttt gtcatctcat gaacaggatt atccaagtaa tgccaaagaa
     2161 atgaaagatt tagataaaaa aatcgaagaa aaaattgctg gcattatgaa acaatatggt
     2221 gtcaaacgtg aaagtattgt cgtgaataaa gaaaaaaatg cgattattta tccgcatgga
     2281 gatcaccatc atgcagatcc gattgatgaa cataaaccgg ttggaattgg tcattctcac
     2341 agtaactatg aactgtttaa acccgaagaa ggagttgcta aaaaagaagg gaataaagtt
     2401 tatactggag aagaattaac gaatgttatt aatttgttaa aaaatagtac gtttaataat
     2461 caaaacttta ctctagccaa tggtcaaaaa cgcgtttctt ttagttttcc gcctgaattg
     2521 gagaaaaaat taggtatcaa tatgctagta aaattaataa caccagatgg aaaagtattg
     2581 gagaaagtat ctggtaaagt atttggagaa ggagtaggga atattgcaaa ctttgaatta
     2641 gatcaacctt atttaccagg acaaacattt aagtatacta tcgcttcaaa agattatcca
     2701 gaagtaagtt atgatggtac atttacagtt ccaacctctt tagcttacaa aatggccagt
     2761 caaacgattt tctatccttt ccatgcaggg gatacttatt taagagtgaa ccctcaattt
     2821 gcagtgccta aaggaactga tgctttagtc agagtgtttg atgaatttca tggaaatgct
     2881 tatttagaaa ataactataa agttggtgaa attaaattac cgattccgaa attaaaccaa
     2941 ggaacaacca gaacggccgg aaataaaatt cctgtaacct tcatggcaaa tgcttatttg
     3001 gacaatcaat cgacttatat tgtggaagta cctatcttgg aaaaagaaaa tcaaactgat
     3061 aaaccaagta ttctaccaca atttaaaagg aataaagcac aagaaaactc aaaacttgat
     3121 gaaaaggtag aagaaccaaa gactagtgag aaggtagaaa aactttctga aactgggaat
     3181 agtactagta attcaacgtt agaagaagtt cctacagtgg atcctgtaca agaaaaagta
     3241 gcaaaatttg ctgaaagtta tgggatgaag ctagaaaatg tcttgtttaa tatggacgga
     3301 acaattgaat tatatttacc atcgggagaa gtcattaaaa agaatatggc agattttaca
     3361 ggagaagcac ctcaaggaaa tggtgaaaat aaaccatctg aaaatggaaa agtatctact
     3421 ggaacagttg agaaccaacc aacagaaaat aaaccagcag attctttacc agaggcacca
     3481 aacaaaaaac ctgtaaaacc agaaaactca acggataatg gaatgttgaa tccagaaggg
     3541 aatgtgggga gtgaccctat gttagatcca gcattagagg aagctccagc agtagatcct
     3601 gtacaagaaa aattagaaaa atttacagct agttacggat taggtttaga tagtgttata
     3661 ttcaatatgg atggaacgat tgaattaaga ttgccaagtg gagaagtgat aaaaaagaat
     3721 ttatctgatc tcatagcgta aggaatagca gtagaaaaag tctgaatcaa aaatgaagtt
     3781 ctctcaaaag ttagaaataa aactctga
//
LOCUS       DAVMAH010000091         3774 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVMAH010000091 DAVMAH010000000
VERSION     DAVMAH010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3774
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.092"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            69..287
                     /gene="nrdH"
                     /locus_tag="VYO94_001975"
     CDS             69..287
                     /gene="nrdH"
                     /locus_tag="VYO94_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV1760543.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            368..2527
                     /gene="nrdE"
                     /locus_tag="VYO94_001976"
     CDS             368..2527
                     /gene="nrdE"
                     /locus_tag="VYO94_001976"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV1760544.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            2715..3677
                     /gene="nrdF"
                     /locus_tag="VYO94_001977"
     CDS             2715..3677
                     /gene="nrdF"
                     /locus_tag="VYO94_001977"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV1760545.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
BASE COUNT         1168 a          814 c          704 g         1088 t
ORIGIN      
        1 aaatcattga caaaatttta ttttctgata tactaagata gtattaaatt ttgaagagga
       61 gttacacaat ggtaaccgtt tattctaaaa acaattgtgt ccaatgtaaa atgaccaagc
      121 gtttcttgga cagtaataat gtctcttatc gtgaaatcaa tcttgatgag caacctgagt
      181 acgtcgatca agttaaagag ctcggtttta gcgcagctcc tgttatccaa acaccaactg
      241 aagtcttttc aggtttccaa ccaggaaaac tgaaacaatt agcataatct tagtacatca
      301 tccagaagaa actgctttta gggctaactt agaagccttt cttttgtaat tagataaggg
      361 aaattttatg ggattaaaac atcttgaaga cgtgacttac ttccgtctta ataacgaaat
      421 taaccgtcct gttaatggac aaatcatgct tcataaagat aaggaagcct tggatgcttt
      481 ctttaaagaa aatgtagttc caaacactat ggtttttgat tcaatcaaag acaaaatcaa
      541 ttacctcatt gaacacaact acatcgaaac agcctttatc aagaaatacc gtccagagtt
      601 cttggaagaa ttggctcaat ttatcaaaga ccaaaacttc caattcaagt cattcatggc
      661 agcttataaa ttttacaatc aatatgcctt aaagactaat gacggtgaat actatcttga
      721 aaatatggaa gaccgtgtct tcttcaacgc cctttatttc gctgatggga atgaagctgt
      781 tgcaatcgat attgccaatg aaatcatcca ccaacgctac caacctgcta ctccttcctt
      841 cttgaatgct ggacgtgctc gtcgtgggga gttggtatct tgtttcctaa tccaagtgac
      901 ggatgatatg aactctatcg gacgttctat caactcagct cttcaacttt cacgtattgg
      961 tggtggtgtg ggaattaccc tcagcaacct tcgtgaagct ggtgcaccta tcaaaggcta
     1021 tgaaggagct gcttcaggtg tcgttcctgt tatgaagctt tttgaagaca gcttctctta
     1081 ctccaaccaa ttggggcaac gtcaaggtgc cggtgttgtc tacctcaacg tctttcaccc
     1141 agatatcatc gctttccttt caactaagaa agaaaacgct gatgaaaaag tacgtgtcaa
     1201 gactctatca cttggtgttg tagtacctga taaattctac gaattggctc gtaaaaatga
     1261 agaaatgtac ctcttcagcc cttactctgt agaaaaagaa tacggtgtgc cattcaatta
     1321 catcgacatt actgaaaaat acgatgaatt ggtcgcaaat ccaaatattc gcaagacaaa
     1381 aatcaaggcg cgggatttgg aaactgaaat ctctaaattg caacaagagt ctggctatcc
     1441 ttatgtagtc aacatagata cggctaaccg tgcaaatcct gttgatggaa agattatcat
     1501 gagtaacttg tgttctgaga ttcttcaagt tcaagaacca agcttgatca acgatgctca
     1561 agaattcctt caaatgggaa cagatgtttc atgtaacctg ggttcaacca acgtggttaa
     1621 catgatgact tcacctgatt ttggtcgttc tatccgtgct atggttcgtg cccttacttt
     1681 cgttacagat agttcacata tcgtagctgt accaacgatt gaccatggaa atagccaagc
     1741 ccacaccttt ggtctcggtg ccatgggact gcacagctac cttgcccaac aactcattga
     1801 atatggttca cctgagtctg ttgaatttac aagcatctac tttatgctta tgaactactg
     1861 gaccttggta gagtcaaaca atattgcgcg tgaacgtggt attaccttcc acaactttga
     1921 aaaatcagac tatgctaacg gaagttactt tgacaagtat gtaactggtg aatttgttcc
     1981 aacatcagac cgtgttaaag aactcttcaa aaatgtcttt atccctggtg ttgctgattg
     2041 ggctgaactt cgcgacaagg ttcaagaaga tggtctttac caccaaaatc gccttgctgt
     2101 agcgccaaat ggttctatca gctatatcaa cgacgtttct gcttctatcc acccgattac
     2161 gcaacgtatc gaagaacgcc aagagaagaa aattggtaaa atctactacc ctgctgctgg
     2221 cttgtctaca gaaaccattc cttactacac ttctgcctac gatatggata tgcgtaaagt
     2281 catcgatgtt tacgctgctg cgactgaaca cgtggatcaa ggactttcac tcaccctctt
     2341 catgcgcagt gacattccaa aaggccttta cgaatggaag agggaaaata aacaaacgac
     2401 acgtgacttg tccatccttc gtaactatgc ctttaacaag ggaatcaagt ctatctacta
     2461 cgtccgtacc tttacagatg acggtggaga agtcggcgcc aaccaatgtg aaagctgtgt
     2521 gatttagttt ctagcataga aacactattt ttccctaagc agcactgata aaatcaaatc
     2581 tactatgtca taacataatt tatgtaacat tttaaaagtc gggcttccga ctttttgtgc
     2641 gatactccta tagaattatg gtaaagtaga aataattgtg agttcgcaat actaaacaca
     2701 gaaagagatt ttaaatggaa acttactaca aagccattaa ctggaatgcc atcgaagatg
     2761 tcatcgacaa atcaacttgg gaaaaactga cggagcaatt ttggctcgat acacgtattc
     2821 ccttatcaaa cgacttggat gactggagaa agctatctaa caaagagaaa gacttggtcg
     2881 gaaaagtttt tggtggttta acccttcttg acactatgca atctgaaact ggggttcaag
     2941 cccttcgcgc agacatccgt acaccacatg aggaagctgt cttcaataac atccaattta
     3001 tggaatctgt ccacgctaaa tcttactcat caatcttttc taccttgaat actaaggctg
     3061 agattgaaga aattttcgaa tggaccaata ccaatcctta cctacaaaag aaggctgaga
     3121 ttgtcaacga aatctaccta aacggcagcc cacttgaaaa gaaagttgcc agcgtcttcc
     3181 tcgaaacctt cctcttctac tctggtttct tcactcccct ctactatctc ggtaacaaca
     3241 aacttgccaa cgttgcagaa atcattaaat tgattattcg tgacgagtct gttcacggaa
     3301 cctacattgg ttacaaattc caacttggtt tcaatgaatt acctgaagaa gagcaagaaa
     3361 aactcaaaga atggatgtac gacctactct atactcttta tgaaaatgaa gaaggctaca
     3421 cagagagtct ttatgacggt gttggttgga ctgaagaggt taaaaccttc cttcgctaca
     3481 atgccaataa agctctcatg aacatgggac aagatccact tttcccagat tcagctgaag
     3541 atgtcaaccc aatcgttatg aacggtattt caacaggaac ttccaaccat gacttcttct
     3601 ctcaagtcgg aaatggttac cttcttggcg aagttgaagc catgcaagat gatgactaca
     3661 actacggttt ggactaatac tcttcgaaaa tcaaattcaa accacgtcag cttcgccttg
     3721 ccgtactcaa gtacagcctg cggctagctt cctagtttgc tctttgattt tcat
//
LOCUS       DAVMAH010000092         3747 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVMAH010000092 DAVMAH010000000
VERSION     DAVMAH010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.093"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(189..800)
                     /gene="rpsD"
                     /locus_tag="VYO94_001978"
     CDS             complement(189..800)
                     /gene="rpsD"
                     /locus_tag="VYO94_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV1760546.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(995..2047)
                     /locus_tag="VYO94_001979"
     CDS             complement(995..2047)
                     /locus_tag="VYO94_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1760547.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2044..2742)
                     /locus_tag="VYO94_001980"
     CDS             complement(2044..2742)
                     /locus_tag="VYO94_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1760548.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2909..>3747)
                     /gene="pavB"
                     /locus_tag="VYO94_001981"
     CDS             complement(2909..>3747)
                     /gene="pavB"
                     /locus_tag="VYO94_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1760549.1"
                     /translation="KPDLDNIVATKKVTININGLISKETVQKAVADNVKDSIDVPAAY
                     LEKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGE
                     NVKTKGQYFYQLALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIV
                     ATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTNTM
                     AGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNKKE
                     EN"
BASE COUNT         1015 a          837 c          735 g         1160 t
ORIGIN      
        1 ccataaaaga ttataccaca ttgtgtacta tttttggttc attttactat atcactttgg
       61 actatatcgg tctagttatg tctcaacgat tatagctgga tactaagaga aatcaaaaaa
      121 gcactaaggg agaacgtccc aaagtgctta atatcaaggc ctcaaagcct atcttattca
      181 ataaaatatt acaacatttt gttgtagaat tcaacgacaa gtgcttcgtt gatttctggg
      241 ttgatttcgt cgcgttctgg caagcgagtc aatgaacctt ccaacttttc agcgtcgaat
      301 gatacgaatg ctggacgtcc aagagtagct tctactgctt caaggattgc tggaactttc
      361 aatgattttt cacgaactga gatcacttga cctggagtta cgcggtatga tgggatatca
      421 acgcgtttcc cgtcaacaag gatgtgaccg tggtttacga attgacgagc ttgacgacga
      481 gtagtcgcga gaccaagacg gtaaacaacg ttatccaaac gacgttccaa aagaagcata
      541 aagttgaaac ctaggattcc gcctttgatt tttgtagctt gtacgaacaa gttacggaat
      601 tgtttttcac ctacaccgta agtgaaacga agtttttgtt tttcagccaa ttgcaaaccg
      661 tattctgaca atttagaacg gttgtttggt ccgtgttgtc ctggtacgta gttacgacgt
      721 gccaattctt tacctgtacc tgtaagtgaa aggccaaggc gacgagcttg tttccaagat
      781 ggtcctgtat aacgtgacat atgaatgtcc tcctgatata aataatattt cggtggaaat
      841 agtcacttag aaagccctga ttcgtgcaga tgcccttcgc ctaaacagcc aaggttactt
      901 gtcataagac acctgttgac gagcttcatg ctttcctgct gatatttcac acaaaatcta
      961 ttctaccatg aatagctgga tttgtaaagg ggttttaggc tttattttca ctaccagaga
     1021 ggttgagaac gagggtaaag gtacttccta gaccgtactg gctgctgact gtgatttccc
     1081 cacccaattg atgggccaat tcacgcgcaa tcgcaagtcc taatccatga ccacctgtct
     1141 tcatgttacg cgaagtttcg acacgataaa gacgtttgaa aatattttcc aaatcctctg
     1201 gggcaatacc ctgcccttca tcggtcacac tgattgaaag ctggtccttc tccagcttag
     1261 ccaccacttc cagcttggtt cctggagcag aatatttaaa agcgttatcg accagattca
     1321 ccaagatacg agaaagctta gcataatctc cctcaatccg ggcagactct gggattacct
     1381 gcaagtggac atctcttctc tcctgctcaa tcaaaaactg aaattcactc atgcactcaa
     1441 ttaagagctt gtccagaaaa atactgtctt tactggtagt ttccacctga tttctagctg
     1501 tgtttagggt caaaaaattc aactcctcaa ccagtttatt gagcctctcc gtctggcgtc
     1561 caatggttgc tagataatga gcttgctccg actccttgat aatcccatcc aaaatccctt
     1621 ctaccgtcgc ttgaatcgaa gtgatagggg tcttaatatc atgcgacaac tgggcaatca
     1681 tcaagccctt ttctcgttcg ctttcttcca aggaatcaaa gcttacctgc aaatcatggg
     1741 acatctcatt aaaagtttgc cctaattgct gaaattctac aggaccttga acctccaaat
     1801 ttgaaggaaa atccttggcc gctacccgct tggcatgctc cttgagtttg cccaacgacg
     1861 taaagactgg caataggaga aagagactaa tcccagcacc gacaaggctg gcaacgatgg
     1921 tcatcccaag caaaaagtaa atctcgcctt tcgcaatcag cattttttga acagcccaaa
     1981 aaacaaccaa aatggttaag agggttgaaa taatatatcc aaccaaaata taacttttta
     2041 gtttcatgtt tgtcctctcg gtttctctat cttatatccc aacccccaaa ctgtcttaat
     2101 agtgggcgtt tggtcactac tatattttgc cagctcctgt cgaagagcat ggatatgcac
     2161 attcaaggta ttggtgtcat ccacgtagtc ttctttccag atcttttcat agaggtctgt
     2221 cttggagaaa actcgctctg gattgctagc taaaatccac agcaattcaa atgatttaac
     2281 agttaaatcc agcatttctt ctcctatttg aacttcatga ctactatgat tcatttttag
     2341 attgccaagg gaaatcagct ctgtttcgcc cccacgatga aggcggcgca aaatattgtg
     2401 gacacgcaaa actagctcac gtgggctaaa aggcttagca ataaaatcat ctgctcccaa
     2461 gctcaggccg taaatcttgt cctgttcact ggtcttagca gtaataaata ggaaaggctg
     2521 ctctggtgat aagtattgaa cctcactgat taaatcataa ccatccatcc gaggcatcat
     2581 gacatctgtg ataatcaaat caatcggttt tttcttgaac agctctagcg cttccagtcc
     2641 atcatgggct accaagacct gataacctgc ctgaattaag tatctctgat gaatatctgt
     2701 gatttctacc tcgtcgtcaa cgagtaaaat tgtctttccc atctgtctct cctttgataa
     2761 aaacagtgct atactgcttt aagtataaca ctatttttat tgttttacga tgattttaat
     2821 ctgctattga aagaaagtcc tgattgctga ttgagttgtt aaactaatct tagtcagccc
     2881 actatccatc atttatttcc ttagctgatt agttttcttc ttttttgttt ttcaaaccta
     2941 gaccaccgag taaacctgca agcgcaagcc caaggaaacc aatacttgcc attgatgttt
     3001 gagtctcacc agtatttggt agcatagctt tatcctctga catcatcgta tcagacatct
     3061 tgttagcaga agcagccatg ttttcacctg ccatcgtgtt ggtagaactt gtcatggtgt
     3121 cagcaggcat gctatctgta gtacctgtag catgattgtg attcatcgga gtcacgccag
     3181 aaccagagtt agaaggtgat aatgaaccat ttgctgtgtc tgatgtttct ttaacattta
     3241 tcttaatagt gactttttta gttgctacga tgttgtccaa gtctggttta ccgtctttgt
     3301 taccatagac attgactgta gcgctgtaag tttgagtacc gtttgctcgg aactggtcaa
     3361 tgagcgcttg tttttctttg ccagctacat ttccgtccaa ggctaattga tagaagtatt
     3421 gacctttggt cttcacgttt tcacctagtg gagatagggc tgggttttta gcgtcaccgt
     3481 tatctgacca tggtgccttg tcagatgcct tgagcaagag acgagtcaac ataccatcac
     3541 ctgcgaagag ttcgtatgga atcacatggt tgacacctgc tgtgaatgga ccttcaccct
     3601 tggccttttc taggtaggct gctggaacat cgatactgtc cttaacgttg tctgcaacgg
     3661 ctttttgaac tgtttcttta gaaattaaac cgtttatgtt aatagtgact tttttagttg
     3721 ctacgatgtt gtccaagtct ggtttac
//
LOCUS       DAVMAH010000093         3670 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVMAH010000093 DAVMAH010000000
VERSION     DAVMAH010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3670
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.094"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..1022
                     /locus_tag="VYO94_001982"
     CDS             <1..1022
                     /locus_tag="VYO94_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1760550.1"
                     /translation="AEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLIGY
                     LLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKDVE
                     FAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDEGQILIDGKDI
                     KEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIEKM
                     DKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQESLN
                     NLVKDKTVVIISHRMKSIENTDKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTKMA
                     EEFIY"
     gene            1033..1617
                     /locus_tag="VYO94_001983"
     CDS             1033..1617
                     /locus_tag="VYO94_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1760551.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            1617..2312
                     /locus_tag="VYO94_001984"
     CDS             1617..2312
                     /locus_tag="VYO94_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1760552.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAEIKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            2300..3664
                     /locus_tag="VYO94_001985"
     CDS             2300..3664
                     /locus_tag="VYO94_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760553.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRVAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         1341 a          458 c          697 g         1174 t
ORIGIN      
        1 aggcggaagt aactacaatt ttaactttgt ctatatcttc aatatttagc tttatatctc
       61 ttgctgttgt gatatttgtc ggcgtaaatc taattattaa taaagagata aattctctct
      121 accttatagg atatttacta gctgctatga agataaaaga ctctttagat gcatctaaag
      181 agggcttgat ggaaatattt tatttatcgc ccaaaataga aagattaaaa gaaattcaaa
      241 atcaagatct acaagaaggc gatgactata gcttaaaaaa atttgatatt gatctaaaag
      301 atgttgagtt tgcctacaat aaagacgcaa aagttttaaa tggtgtaagt tttaaagcta
      361 agcagggaga ggtcactgct ttggtaggtg caagtggctg cggtaaaaca actatcttga
      421 aacttatatc aagactttat gattatgacg agggacaaat cttaatcgat ggcaaagata
      481 taaaagaaat atcaacagaa tctctttttg ataaggtctc tatagttttc caagatgtgg
      541 ttctctttaa tcaaagcgtt atggaaaata ttagaatcgg aaagcaagat gcaagtgacg
      601 aagaggttaa aagagcagca aaacttgcaa attgcacaga ttttatagaa aaaatggata
      661 aaggtttcga tacagttatt ggtgagaacg gagctgagct atcaggagga gaaagacaaa
      721 gattatcaat agccagagcc ttcttaaaag atgcgccgat attgatctta gatgagataa
      781 cagcaagcct tgatgttaac aacgagaaaa agattcaaga gtctttaaat aatttagtta
      841 aagataaaac tgttgtaatc atttcacata gaatgaaatc catagaaaat acagacaaga
      901 tagtagttct tcaaaacgga agagtagaaa gcgaaggtaa gcatgaagag cttttacaaa
      961 aatcaaaaat ttacaaaaat ttaatagaaa agacaaaaat ggcagaagaa tttatttatt
     1021 aggaggacta caatggataa taaaaaatta aaagtaaaag atttagtaag catcggtgtt
     1081 tttggcgtaa tttattttgc cttcatgttt ggagttggta tgatgggctt gattccaata
     1141 ttgttcttaa tatacccgac agtattagcc atagttgcag gaactgttgt tatgttattt
     1201 atggctaagg ttcaaaagcc atgggcacta tttatatttg gtatgatatc accacttgtg
     1261 atgtttgcag ctggtcatac ctacgtagtt gtggttttat cacttatagt aatgataata
     1321 gcagaattaa ttagaaagat tggtaattat aattcattta aatacaatat gctttcttat
     1381 gcaatcttca gcacatggat atgtagctct ttaatgcaaa tgcttttagc aaaagaaaaa
     1441 tatatggagt ggtctttgat gacgatggga aaagattatg ttgatgtatt agaaaagtta
     1501 ataacttatc ctcacatggc tttagtagcc ttaggtgctt tcttaggagg aattcttgga
     1561 gcatatatag gcaaggctct attgaaaaaa cactttgaaa aagcaggcat tgtataatgc
     1621 ctactttttc ttcaaatgct ccctttaatc ccaatccgat ctctaagata ttagtcgtat
     1681 ttatcacagg cttaactgtt atgcatagca taaacatccg ttttgagctg gcaattgttt
     1741 gtcttattgg tattttgctt tatttgaatg gatacaaaaa aacacttttc aaatggatta
     1801 tattgtgtgg gatactttac tccttgccta attttatggt gttatctgaa ttaaacccta
     1861 tagttaagat gtttttgagt atacctattg ttattagaat gtttatttta ccatttatgg
     1921 cagcaagctt tatgataaag acctcggatg taggcgcaat aatttcatcg atggataagc
     1981 ttaagatttc aaagaatgta tccataccta ttgcggttat gtttagattc ttcccatctt
     2041 ttaaggagga gaagaaaaac atcaaaatgg ctatgagagt aagagggata aattttaaaa
     2101 acccagtcaa atatcttgaa tatgtttctg tgccactact cattatatca tctaatatat
     2161 cagatgacat tgcaaaagcg gcagaaataa aggcaataga aaatccaatt gccaagacca
     2221 gatacattcg cgtaaagata cagctaattg attttgttta tgttttagcg gttgttggac
     2281 ttattgtggg aggcttaata tggttgaaat aaaaaattta agtcttgatt atggtgaaga
     2341 gcatatatta gatgatatat cactatccat agccgaggga gagtgcgtgc tatttacagg
     2401 aaaaagtgga aatggtaagt catctttaat aaattcaatc aatggactag ctgtaaggta
     2461 tgataacgca aagacaaagg gcgaaatcat tattgatggt aagaatataa aaaatttgga
     2521 actttatcaa atctcaatgc ttgtttcaac tgtttttcaa aatcctaaga cctatttttt
     2581 taatgtcaat acgacattag aattattatt ttatttggaa aatatcggtc ttgcaagaga
     2641 agagatggac aggcgtttga aggatatgct tgagatattc ccgataaaaa atcttttgaa
     2701 cagaaatata tttaatctat ccggcggtga aaaacaaatt ctttgcattg cagcttctta
     2761 tatagcaggt acaaagatta tagttatgga tgagccttca tcgaatttag atattaaaag
     2821 cataagtgtt ttggcaaaga tgctaaagat attaaaagag aaaggcataa gcataattgt
     2881 tgcagagcat agaatttatt atttgatgga catagttgac cgtgtatttt taatagataa
     2941 aggaaagctt aaaaaaactt atactagaag tgaattttta aagctagata aaaatgaatt
     3001 aaatgcttta agtttaagag ataaagaatt aagtaaatta aaagttcctt atttaaaaga
     3061 aggtggagag tatcagataa aaaatcttag ctacaaattt actgatgatg agtgtttaag
     3121 cttaaaagat atttcgttca agcttgggaa aatttatggc ataataggat ccaacggacg
     3181 aggaaaatca acgcttttaa gatgtttaat aggtcttgag aaaaaatcaa aagaagaaat
     3241 ttattttaag ggagagaagc tatctaaaaa agaaagactc aaaaactctt cacttgttat
     3301 gcaagatgta aatcatcaat tattcacaga tgaagtattc aacgagctta gattaggagt
     3361 aaagaatttt gatgaagaaa aggcgaaaat cattttaaaa gatttaggcc tggacgaatt
     3421 tattgaaagg catccgatga gtttatcagg agggcaaaag caaagggttg caatagcatc
     3481 tgttatgtgc aagaattctc catttgtctt ttttgacgaa ccttcaagtg gtatggatta
     3541 ttccaatatg ataaaaatat ctgaactgat taataagtat aaaaccatgg ataaaataat
     3601 ttttattgtt tcccatgata tagaattttt aaatgaagtg gcagatgaaa tttttgaatt
     3661 gtaaaataga
//
LOCUS       DAVMAH010000094         3460 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVMAH010000094 DAVMAH010000000
VERSION     DAVMAH010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.095"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            54..965
                     /locus_tag="VYO94_001986"
                     /pseudo
     CDS             54..965
                     /locus_tag="VYO94_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(998..1338)
                     /gene="tnpB"
                     /locus_tag="VYO94_001987"
                     /pseudo
     CDS             complement(998..1338)
                     /gene="tnpB"
                     /locus_tag="VYO94_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1657..1956)
                     /locus_tag="VYO94_001988"
     CDS             complement(1657..1956)
                     /locus_tag="VYO94_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV1760554.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            complement(2121..2528)
                     /locus_tag="VYO94_001989"
     CDS             complement(2121..2528)
                     /locus_tag="VYO94_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1760555.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATPFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKID"
     gene            2654..3460
                     /locus_tag="VYO94_001990"
                     /pseudo
     CDS             2654..3460
                     /locus_tag="VYO94_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; incomplete;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         1088 a          622 c          680 g         1070 t
ORIGIN      
        1 atttatagaa atattttagc agccaaggtg tactgttata gattcaatac actatagact
       61 gtaatcaaac aacgatttgg cgaaatgtaa aaaaatatga ggagttcgga ctcgactctc
      121 tccttcaaga aacacgtggt ggtcgtaacc atgcatatat gacagttgag gaagaaaaag
      181 cctttcttgc ccgccatttg aaggctgcag aggcaggaga atttgttaca attgatgcct
      241 tatttcaggt ttataaaaag gagttaggtc gttcctacac acgtgatgcc ttctatcaac
      301 tgttgaagcg ccatggttgg cgaaatatta cgccacgtcc agaacatcct aagaaagcag
      361 acgctcaaac cattgtcgcg tctaaaaata aaatctcaat tcaagaaaaa aagaaagcgc
      421 tttaaaacca gtagacgttt tcgtaaggtt cgcttgatgt accaagatga ggctggtttc
      481 ggtagaatca gtaaactggg atcttgttgg gctccaatag gagtaggtcc acatatccat
      541 agtcactata tatgagaatt tcgctattgt tatggagctg ttgatgccta tacaggcgaa
      601 tcatttttct taatagctgg tggatgtaat actgagtgga tgaacgcctt tttagaagag
      661 ctttcacaag cttatccaga tgattatctt ttactcgtta tggacaatgc tatatggcat
      721 aaatcaagta ccttaaagat tccgactaat attggtttta cctttattcc tccatacaca
      781 ccagagatga acccattgaa caagtgtgga aagagattcg taaacgtgga tttaagaata
      841 aagcctttcg aactttggaa gatgtcatga atcaactcca agatgttata caaggactgg
      901 agaaggaggt gataaagtcc atcgttaatc ggagatggac tagaatgctt tttgaaagca
      961 gatgagtata aaaagaaagt cctcatttca atagaaatca cgactttctg atggatttat
     1021 ttttggagtg atagaaaagc ccttcataag ccagtctact tgttcagatg tgagagcttt
     1081 gacatccttt tctgtactgg gccaagtcag tctgccgttc tcaaagcgtt tatatagtag
     1141 ccaaaatcct tgaccatccc agtaaagggc tttaaagcgg tctttacgtc caccacaaaa
     1201 gagaaagact tgaccggaga aaggatccaa ttcaaagtgg gttttaacta cataggctaa
     1261 tgagtctatt ccctgcctca tatctatctt gctacaaaca aggtgaactt gacctaaatc
     1321 acttagttga attatcatag tacaatacct ttcctccgat aattattttt tatctagtat
     1381 actggaagtt ggggaattag gatagatacc ttgttatgac gcgcttacgt aacttgtaac
     1441 tagctgccta gtttgatctt tgcttcttca ttgattagca gtagatttca aaatgataaa
     1501 aacgcataat agtgggtgta gaatgaactg ccccccaaaa agttagacag aaaaaatcta
     1561 actttttggg gtcagtacaa aactcttgct actatgcgtt ttattatgga aagacttatt
     1621 ggactttctc tcaaatcgag tttttactca attttcttac ttgattggga ttgaaattcc
     1681 aattaatttc tctgagtaga gtgtcttgat attggcttca tcaacagagg ccttatcaat
     1741 tttacgtttc aagaaaaatt cttgaatggt ttcgatttca ggctcacgaa tagcacggtg
     1801 tttgtttgag atgaggattt catagtgaag cggagcttgg gtaaaaataa catctgtatt
     1861 ccctgcagaa taaacctcaa caagggttgc atcggtactt tctagctgac tttttacaag
     1921 ttgcgagtgt gagtttgtcg tattgataag cttcataata tttcctccga ttttttaatt
     1981 ctattatagc actttttgaa taaagtcgct tgatttatac tcaatgaaaa tcaaagagca
     2041 aactaggaag ctagccgcag gctatacttg agtacggtaa ggcgacgctg atgtggtttg
     2101 aattttattt tcgaagagta ttagtcaatc ttatgctgtt ttttccaaga ttcaatggcc
     2161 catttatggc taccacgttt aaggttttgg atagcctcgt caatagggaa ccaggcaata
     2221 tgattaaagt tttctagtgg cttttgtact tctttgaaag gagttgcttc atagaggtag
     2281 gcaggattgt agtagtaggt atcacgatga cgagaataga aatattcgtc agcttgtccg
     2341 taataggtac caatttctgc tgtgaaacca agctcttcaa tcaactcacg ctttagggct
     2401 tcctgatgat tttcacctgc ttcaatttct ccacatggta ggaaccaagc accatttggt
     2461 tcttgaacaa gaacaatttg tttttgttca ggattaggga taactgcata tacgccatag
     2521 cgagcaatat agtctgtatt cgcttttttt ctccgaaagt tgggtttgcc attgcatttt
     2581 cctcattatc tagtatcgtt attattatag tgaaatgaac caaaaatagt acacaatgtg
     2641 gtataatctt cttatggcat attcaataga ttttcgtaaa aaagttctct cttattgtga
     2701 gcgaacaggt agtataacag aagcatcaca cgttttccaa atctcacgta ataccattta
     2761 tggctggtta aagctaaaag agaaaacagg agagctaaac caccaagtaa aaggaacaaa
     2821 accaagaaaa gttgatagag atagacttaa aaactatctt actgacaatc cagacgctta
     2881 tttgactgaa atagcttctg aatttggctg tcatccaact accatccact atgcgctcaa
     2941 agctatgggt tacactcgaa aaaaagaacc acacctacta tgaacaagac ccagaaaaag
     3001 tagccttatt tcttaagaat tttaatagtt taaagcacct agcacctgtt tagattgacg
     3061 aaacaggatt cgatacttat ttttatcgag aatatggtcg ctcattaaaa ggtcagttaa
     3121 taagaggcaa agtatctgga agaagatatc agagaatttc tttggttgca ggtctaacaa
     3181 atggtgagtt aatcgctcca atgacttacg aagagacgat gacgagcgac ttttttgaag
     3241 cttggtttca gaagtttctc ttaccaacat taaccacacc atcggttatt attatggata
     3301 atgcaagatt ccatagaatg ggtaagttag aactcttgtg tgaagagttt gggtataacc
     3361 ttttacctct tcctccctac tcacctgagt acaatcctat tgagaaaaca tgggctcata
     3421 tcaaaaagca cctcaaaaag gtattaccaa gttgcaatac
//
LOCUS       DAVMAH010000095         3399 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVMAH010000095 DAVMAH010000000
VERSION     DAVMAH010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3399
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.096"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            153..2786
                     /gene="polA"
                     /locus_tag="VYO94_001991"
     CDS             153..2786
                     /gene="polA"
                     /locus_tag="VYO94_001991"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV1760556.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYLQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKSYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            2871..3308
                     /locus_tag="VYO94_001992"
     CDS             2871..3308
                     /locus_tag="VYO94_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV1760557.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
BASE COUNT          925 a          598 c          862 g         1014 t
ORIGIN      
        1 ttatagattc aatatactat attatagcac atttttaaat ctaggtttac taaattctct
       61 ggctctatct atttattcgg aaaaagtttg aaaaatactt gctctagctc ttcccaatgg
      121 tattttttga ttctttcctt tataatgggt gtatggataa gaaaaaatta ttattgattg
      181 atgggtcttc tgtagctttt cgggcgtttt ttgcgctgta tcagcagttg gaccgtttta
      241 agaatgcggc tggtttgcat accaatgcga tttatggttt tcagttgatg ttgagtcatt
      301 tgttggagcg ggttgagccg agtcatattt tggtggcttt tgatgcggga aagacgacct
      361 tccggacaga gatgtatgcg gactataagg gtggtcgggc caagactcct gatgagtttc
      421 gtgagcaatt tcctttcatt cgtgagttgc tggatcatat ggggattcgt cactatgagc
      481 tggctcagta tgaggcggat gacatcattg ggacgctgga taagctagca gagcaggatg
      541 gttttgatat taccattgtc agtggggaca aggatttgat tcagctgacg gatgagcata
      601 cggtggttga aatttccaag aaaggtgtgg ctgagtttga ggcctttacg ccagattacc
      661 tcatggaaga aatgggcctc acaccagctc agtttatcga tctcaaggcg ctcatgggtg
      721 ataagtcgga taatatccct ggggtgacca aagtcggtga aaagacgggt attaagctct
      781 tgctggagca tggttcgctt gaggggattt atgaaaatat tgatggaatg aagacttcta
      841 agatgaagga aaatctcatc aatgacaagg aacaggcctt tttgtctaaa acactagcga
      901 ccattgatac caaggcaccg attgcgattg gtttagagga cttggtctat agtggtccag
      961 atgttgaaaa tcttgggaaa ttctacgatg agatgggctt caaacagctc aagcaggctt
     1021 taaatgtgtc gtcagctgat gtgtctgaga gtttggattt tactattgtt gaccaaatca
     1081 gtcaagatat gctgagtgaa gagtctatct tccactttga gctttttggt gagaattacc
     1141 atacggataa tttggttgga tttgcctggt cttgtgggga taagctctat gccacagaca
     1201 agcttgagct gttgcaagac ccgattttca aggatttctt agaaaaaaca tctctgagag
     1261 tttatgactt taagaaggtt aaagttcttt tgcaacgttt tggtgtggat ttgcaggcgc
     1321 ctgcttttga catccgtttg gctaaatacc tcctttcgac tgtggaggac aatgaaattg
     1381 cgaccatcgc tagtctttat ggtcagactt acttggttga tgatgaaact ttctacggta
     1441 agggtgttaa aaaggccatt cctgaacgtg agaaattctt ggaacactta gcttgtaaac
     1501 ttgctgtttt ggtagaaaca gagcctattt tacttgaaaa actcagcgaa aatgggcaat
     1561 tagagcttct ttatgatatg gagcaacctc tggcttttgt ccttgccaag atggaaattg
     1621 ctgggattat ggtcaagaaa gagaccttgc ttgagatgca ggctgaaaat gagcttgtca
     1681 ttgaaaaact gactcaagag atttacgagc tggctggtga ggagtttaat gtcaactcgc
     1741 ctaagcagtt gggcgtgctt ctctttgaga aattgggact tcctctagaa tacactaaga
     1801 aaaccaagac aggttattcg acagcagtgg atgttttgga gcgtctcgct cctattgctc
     1861 cgattgttaa gaaaatcctg gattaccgtc aaattgctaa gattcaatct acttatgtaa
     1921 ttggcttgca ggactggatt ttggctgatg gaaagattca tactcgctat ttgcaggatt
     1981 tgacccagac cgggcgtttg tctagtgtgg atccaaactt gcaaaatatt cctgcccgat
     2041 tggaacaggg gcgcttgatt cggaaggctt ttgtgccaga gtgggaggat agtgtgctac
     2101 tcagctctga ctattcacag attgaattgc gcgttttggc gcatatttct aaggatgagc
     2161 acttgattaa ggccttccaa gagggggcag atatccatac ttcgacagcc atgcgggtct
     2221 ttggcattga gcgtcctgat aatgtgactg caaatgatcg tcgcaatgcc aaggcagtta
     2281 actttggagt ggtttatggg atttcagact ttggcttgtc taataatttg ggaattagtc
     2341 gtaaggaagc caaagcctac attgatacct actttgaacg ttttccaggt attaaaaact
     2401 acatggatga agtggtgcgg gaggcgcgtg ataagagcta tgtagagacc ctctttaagc
     2461 gtcgccgtga gttgccagat atcaattcgc gcaacttcaa tattcgtggt tttgcggagc
     2521 gaactgctat caactcacct atccagggtt cggcagcaga tattctcaag attgccatga
     2581 ttcagctgga taaagccttg gttgcaggtg gttatcagac caagatgctg ttacaagtgc
     2641 acgatgaaat cgtccttgaa gtgcctaaat ctgaattggt agagatgaaa aaattggtga
     2701 aacaaaccat ggaagaagcc attcaactca gtgttcctct tatcgcagat gagaatgaag
     2761 gggcaacctg gtacgaggct aaataaaaag ggggctagtc ctcctttttt gtagtagaat
     2821 tctgcaaacc ttttcaaaat gtgctatact gatgaaaaag gaggatttct atgagtcaag
     2881 aatttatcaa tccaagtgat ggcgtgattc gtcagtatct cgcaacgagt aaaacccttg
     2941 ctgtggtggg tttgtctgac cgtgaagaaa caaccagtaa tcgagtaaca aaggaaatgc
     3001 aggctcgggg ctataaaatc atcccagtca atcccaaggc ggcaggtggc gaaatcttgg
     3061 gtgaaaaggc ttatgctagc ctcgctgaaa ttccttttcc tgtagatatt gtcaatgttt
     3121 atcgtcgcag tgaatttctg cccgatgtgg cgcgtgattt tctcaaagct gatgccaaga
     3181 ttttttgggc acagctagga cttgaaagtt tagaagcgaa agagattttg cgtgatggtg
     3241 gatgtgatga tatcgtgatg aatcgctgta tcaagagaga acatactcgc ttgattgagg
     3301 aagcataaga aaaaggtagc tgatgggcta ccttttgtgt tatactcaat gaaaatcaaa
     3361 gagcaaacta ggaaactagc tgcgggttgc tcaaaacac
//
LOCUS       DAVMAH010000096         3386 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVMAH010000096 DAVMAH010000000
VERSION     DAVMAH010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3386
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.097"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            227..958
                     /locus_tag="VYO94_001993"
     CDS             227..958
                     /locus_tag="VYO94_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760558.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            973..2124
                     /locus_tag="VYO94_001994"
     CDS             973..2124
                     /locus_tag="VYO94_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV1760559.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGNRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(2176..2835)
                     /locus_tag="VYO94_001995"
     CDS             complement(2176..2835)
                     /locus_tag="VYO94_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV1760560.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            2905..3351
                     /locus_tag="VYO94_001996"
     CDS             2905..3351
                     /locus_tag="VYO94_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760561.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
BASE COUNT         1244 a          496 c          680 g          966 t
ORIGIN      
        1 ttatagtgaa ttgaatctgg aatattacac tacggttcct aaaatatttt cagaaagcga
       61 tttgaatttc ccaataaatt tgttcagttt ttaattgatt ttactataga agatataatt
      121 ttctaaatta ctctgacaca gaactttaag aaaaagctaa ttattgtagt aatttattta
      181 agaaaatgat ataattcatt aaaaagtatt tggaggagga agaattatgt tgaatcagga
      241 tctctttgat tcgcttgagg cacaaaaaat tgtagatact ttgatgaaag ggcaaaaaga
      301 ttatgtagat gaacgtctag aaaaaagaga gacaatgata gtgtcgaatg gttatgcatg
      361 gacgcgacct aatcatattg atactgcatt tgcatcagca gatttgtttg agtataaatt
      421 acaattagca ggacagactt ggggatattt agaatttgaa acaaatacag aaaaatatgg
      481 gaaagtattg ttaattataa agggtaagaa gcgacttacg aaccaatttc ctttggtaca
      541 aaaaaataag agtggctact tatttgaata tgctcagatg aatacacttt atcttaatca
      601 acattcttcc tacaaaaatg atgaagatag tcattccttt ccaattcaga tggagttagt
      661 ttctgatgaa atgattcaag aaattgaaca agctactaaa aattcgaata tcgaaaaatt
      721 tatgatttta acttatgagg cggactcaga aaacaatatt atatctgtag atgttgttat
      781 gcctgatgca cgaactggtc agttacactt gattcaagat ttgtctgagt atattcaatc
      841 aagttcgtac catttcgaag aagctaaata ccaagatatt cctaattttt cagaattatc
      901 ggaaacagaa gattttgaaa ttattccaag aatagaaaaa caagaaggtc aaaagtagta
      961 aggagtatgt aaatgtttaa tggtcgggta ttgaaagaat tacggctgtt aaatggttta
     1021 agtagagcag aattagctca gagaattaat ttaacggaac aagccatttg gcagtttgag
     1081 tccaacgaaa cgaaacctaa attatcaacc aaaatgcatt tggccaacca atttcatgtt
     1141 gatttaactt attttgaaca ggaagaagag agcattcgat ttgattcttc tgtaattgcc
     1201 tttagaaatg cagacctagc aacacggaaa acaatagata ttcaaactat gtatttacat
     1261 aaggtagata gtttgattga ttattttgaa agttttgtaa ttatacctaa tattacaatt
     1321 catgacctaa gtaatgtagt gagtgaatct tatcataagg gagaatccat tgaggaattg
     1381 gctctttatg ccagggaaaa attaggtatt tcaaaagata atcatgattt gctttataaa
     1441 ttagaacgtt caggcatcta tatcgtggaa cgattaatta atggccaagc tgatgcttat
     1501 agcgcatggt caaaattggg aagaccttat attgtgttgg gaacgaataa atcatctgta
     1561 cgtcgaaatt ttgacttagc tcatgagcta ggacatattc ttttacacaa atataaagat
     1621 atgaatgaag atggcaatcg tttggagcaa gaagcaaatt attttgcatc atgtttttta
     1681 ttgccaaaag aagagttttt agtcaaattt gaagagaggg ttggcaagcg tgtcagcaat
     1741 cctgatagtt atattttatt gaagtcggat ttgaatgttt cgatacaggc tttagagtat
     1801 cgagctttta agttaggatt attgactcca aagcaacatt cttactttta tcgtcaaatt
     1861 gcgcaaaaag gttacaaaat gattgaacct ttggatgatc aaatttttgt taaaaaacca
     1921 agcaaagtaa agagtattct ggacgtcgtt ttgagtaatc atctagtcag tctagcgact
     1981 ataatgtcta aacaaagtat tcgtttacag tttataagcg aaatattttc agtcgaaatg
     2041 aaattttttg atcagtatca agaagataga agaacagatc gatttgataa catcatccct
     2101 ttgtacaaaa gaaataattt ataatttaac tgtgaaataa tttcatgaag gacatatggc
     2161 agaaattgga ttttatcaga caagcagtag cttaccaaaa ataatcaaac aagtagcaag
     2221 taagaggaaa ggcacgaaag gaagtctttc ctttttcttt tgcaggataa aggccaggat
     2281 acccgtcgca gaagcaaact gaatcaagat cagtaactcc gttacgctaa agacgagagc
     2341 acaagaagct aaaaagagga aatctcctgc gcccatgcgg atatcgataa aatgagccaa
     2401 aattccaaga gcaaggaagg agaccatgac cagattccag ccagaggaag ctattaggat
     2461 taggtggaaa gtcatccaga ccagtaaggg atattcctga tggtgaaagt cgtagatacc
     2521 caaggtcaaa ccagcggtga ttaggacgac ttgccccaag gaaagcaatt cccaagagta
     2581 aagcagaaag aggagtccta agactaattc aaagagggca taccagacag gatagcgaac
     2641 tttgcagtag cgacagcgaa agcgattgaa gacctgtgag agaatcggaa tcaaatctaa
     2701 gggacgcaag cgagtctgac aggaatcgca gtgactggct gaactgataa tggattgctc
     2761 tggaaaacgg tcaatgacca aaccaagaaa ggaagcgaga atgctcccga cgagaaaaaa
     2821 ataaaaatca atcatactta tctattcgta aaaaatggga gaaatagtat aatggagaaa
     2881 catagataag atggtgagga aaagatgaca attcgttttg aagaaaaggt gagtatagaa
     2941 aacgctcaat ttgtatgcca gtggtccaac tccctaggca aatcctttca agaacaatgg
     3001 atgggaccaa ggattccttt tctactgacc cttcaagcct tggaaggagt cttttcaatc
     3061 tttgatgaac aagagtttgt gggacttatc cagaaaatca ggctagaaga cagcaatctt
     3121 catatcggga gattttttat caacccccag aaacaggagc aagacttagg tagccaggct
     3181 ttaaggaaat ttgttagttt ggcctttgaa aatgaagata tagatagtat ttctctaaat
     3241 gtcttcgagg caaatcaaag agctcagaat ctttaccaaa aagaaggatt tgaaatcgtt
     3301 caaatggttg aagcacctgt acgaaaatat agtagattga aactagaata gtacacctct
     3361 acttctaaaa cattgttaga aatcga
//
LOCUS       DAVMAH010000097         3146 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVMAH010000097 DAVMAH010000000
VERSION     DAVMAH010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3146
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.098"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            74..556
                     /locus_tag="VYO94_001997"
     CDS             74..556
                     /locus_tag="VYO94_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009431600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickase"
                     /protein_id="HEV1760562.1"
                     /translation="MEDVEKKILYYEIYKAKKEVYEEYQKKNIFTKEAFYNKHKKDID
                     QYKVVSGKLKKLLSDKEKLSPKKWNEEKILLMSNLEEINKEKDKIKDEYQEINHIKYS
                     VDFVNKELGIDLSIEIDKLIKQGEKPSVIAQIKKFQDQVNKDNEYREMMKNKKMDQER
                     "
     gene            630..803
                     /locus_tag="VYO94_001998"
     CDS             630..803
                     /locus_tag="VYO94_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760563.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            989..1440
                     /locus_tag="VYO94_001999"
                     /pseudo
     CDS             989..1440
                     /locus_tag="VYO94_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
     gene            1567..2295
                     /locus_tag="VYO94_002000"
     CDS             1567..2295
                     /locus_tag="VYO94_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV1760564.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKS
                     TPIFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWY
                     EEDKDKLRQKGLNKKMNYDVGESL"
     gene            2979..3140
                     /locus_tag="VYO94_002001"
     CDS             2979..3140
                     /locus_tag="VYO94_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760565.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDSTPAKNQEMKNSFD
                     MAKTQIETD"
BASE COUNT         1500 a          402 c          535 g          709 t
ORIGIN      
        1 acaaacaaaa atagaaactt taaagtctaa tagttatagg ctaaataaaa aagcaaagac
       61 aatccataaa gaaatggaag atgtagaaaa gaaaattcta tactatgaaa tctacaaagc
      121 caaaaaagaa gtttatgaag aatatcaaaa gaaaaatata ttcacaaaag aagcatttta
      181 taacaaacat aagaaagata tagaccaata taaagtagta agtgggaaat taaaaaaact
      241 cctatcagat aaggaaaaac taagtcctaa aaagtggaat gaagaaaaaa ttcttttaat
      301 gtcaaatctt gaagaaataa ataaagaaaa agacaagata aaagatgaat accaggaaat
      361 taatcatata aaatattcag tagattttgt aaacaaagaa cttggtatag atttatccat
      421 agaaatagat aagctaataa aacagggaga aaaaccaagt gtaatagcac agattaaaaa
      481 gttccaagac caagtcaata aagataatga atacagagaa atgatgaaaa acaagaaaat
      541 ggatcaagaa agataagacc tggtaaaaat atcttatcca agctataata tgaccaaaca
      601 actaaagtca gatctaggag gtaatagaga tgaataaaag gcaagagcta atagatgaac
      661 tcataaaagc aaatgaagat ggaacataca aaacctataa aagcacagaa gaaataaaag
      721 caatgaacaa tgaagaaata cagattatat attccaacat gaaaaactat ctatcagaca
      781 aaagaacaca cataaactat taaaggtgga aaggtagtgt aagctatttt taaaagtata
      841 aaaggtacaa agacctaaga aatatataaa aacatcaaaa taaagtattc caccaccaag
      901 aacaataaaa taaaaacaag caaagggaag tatagaaaaa ttaaaaccta tacttccctt
      961 ttttaattca aacaaaggag agaaaagcat gataaacgaa gaaataagca aggaagcagg
     1021 tcaagcagca caaaccataa tatcatacac aataaaggca acaaaagaat caatcaattt
     1081 agaaaaagaa ataagaaaaa agatgaatga aactttagaa aaagcaaatg gaaacttaaa
     1141 aagtcttatg ggcgatgaaa tgaaaataaa agacctctac aagaaaggac aactagaaaa
     1201 tataagcata gatcaaatcg acctcaaaga cttaaaaaaa gaactaaaca aacttggagt
     1261 aagtttctca gtaatgaaaa acaaagaaag caaaaactat gaaatattct tccaagccaa
     1321 agacataaaa gtaatggaat atgcctttaa gcaagtcata gccaaggaaa agaaaaagga
     1381 aaaaggaaag taaaagaaaa agtaaaacca aacaaaaaag atatgaccag agaaatctaa
     1441 agggagtaac gaaaagttac acccttaaat aaccataata acaagacttc cgaaaaacag
     1501 aagtccagaa ttccgaaaat cggaaatcaa gaatttcgat tatcgaaaat caagaaagga
     1561 gcagatatgg caacaaacaa aagatactat tggataaaat taaaagaaga atttttcaca
     1621 gacaaaagga taaaaaggtt aaggagaata tctggaggag atacctatac gataatatac
     1681 ctaaaacttc tactactaag cctaaaagat gagggtaaac tctattatga cggagtagaa
     1741 agtgatttta taaaagagtt agcactaacc atagatgaaa cagacgatga tgtaatggta
     1801 acagtaaatt atttaatcaa tcaaggctta ttagaagttg taacagaaaa tgatgaatac
     1861 tacctaactg aaataccaaa cttaatcgga tcagaaacag cctgggcaga gaaaaaaaga
     1921 agatacagac aaaataaaca gaggacattg tccttaatga gtccaaccca tgtccgacaa
     1981 gagatagaga tagagaaaga tatagagata gataaagaga gagagggaga gatagataaa
     2041 aagtccaccc ccatttttta tggagaattc aaaaatgtaa ggttaagcaa agaagaatat
     2101 aaaaatctaa aagaaaaatt aaactcacac acagatataa tgataaataa actatccaga
     2161 tacatggaaa gcagtggtaa gacctatcaa aaccactatg tgacaatctt aaaatggtat
     2221 gaagaagata aagacaaact aagacagaaa ggtttaaata aaaaaatgaa ttatgatgta
     2281 ggagaatctt tatagataaa aagaggtgga aaggcactat taaagacttt aagtctaaaa
     2341 aggtatcaaa gtatgccaga gataaaaaaa tataaatatg acactttaaa ggcgattaga
     2401 aaattaaaga aatgctagaa gacttttaga tgacagttac caagagggtc taattttcac
     2461 tgctacttat gcagtgggaa ttggaccttt ttatataagc aaattctatt tcaaaattgg
     2521 ttaccaagaa agacttcttt tcactgttaa gtataagagg gtaatttata gaattttgtt
     2581 acatcaagat aaatattttc tgatggtcaa attttaaaaa gattaataac tctcgataaa
     2641 ttttgaacct taacaattga atagaccaag acaagacgtt aattattttt ggagcgtaat
     2701 aacctattcg tcaagatctt tcggctgaat aattcgacaa aaaaagttct gctaaacaaa
     2761 aagaaagtga gcgataagta agagtttgaa tatagggagg gataccctat ccgctatgaa
     2821 gaaaatgagg ataatgatac ttctaaggtt gaagccggct catccggaat agaggcggag
     2881 gtgagattcc tatgttgcta atccaaagca cttgtcaatg tcaaaaaact taattaaaca
     2941 aataattatt agatataaaa ctttagagaa ggtatatatt ggacaatgac tggaatggat
     3001 tggctgattt aatagcaaat ctgattgcaa aatatgctgg tgctttagat ttagataatc
     3061 tacccgattc aacgccagca aaaaatcaag agatgaaaaa tagttttgac atggcaaaaa
     3121 cacaaattga gacggactaa taaaag
//
LOCUS       DAVMAH010000098         2949 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVMAH010000098 DAVMAH010000000
VERSION     DAVMAH010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2949
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.099"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(132..665)
                     /locus_tag="VYO94_002002"
     CDS             complement(132..665)
                     /locus_tag="VYO94_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV1760566.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(754..1530)
                     /gene="recX"
                     /locus_tag="VYO94_002003"
     CDS             complement(754..1530)
                     /gene="recX"
                     /locus_tag="VYO94_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV1760567.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1568..2923
                     /gene="rlmD"
                     /locus_tag="VYO94_002004"
     CDS             1568..2923
                     /gene="rlmD"
                     /locus_tag="VYO94_002004"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1760568.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT          937 a          533 c          538 g          941 t
ORIGIN      
        1 ctgcataaat ctctttctag taatgtgttg taactctgct ataatggatt tattcctttt
       61 tgtgtttaca caatttattt tatactacca aaaaaacaag gtcaggattt tgttcctgac
      121 ctttgacaac tttaccgatt ctttagttct acatagcgct tgtaccaaat gtttacatag
      181 gcttctgaga aaggaccacg tccattgtta atccaatcaa caagaatttt gacatgttct
      241 tttaaaatat agtccaagtc atcagaataa ttcattttgc gtttgtgacg ctcgtactct
      301 tcaacgtcca agagacgttt ttccccatct gtaaaaattt taacatccaa atcgtaatca
      361 atatacttca gtgcttcttc atccagatag taggggctag ccatattgca atagtaagaa
      421 gttccattat cacgaatcat ggcaatgata ttaaaccaat atttcttgtg aaagtaaaca
      481 atagccggtt ctcgagtgac ccaacgacga ccatcacttt cggtaacaag tgtatgatcg
      541 ttgacaccaa taatggcgtt ttctgttgtt tttagtacca tggtgtcccg ccaagttcgg
      601 tggagactcc catcatgctt ataactttga attgtaataa agtcgccttc ttttggaagc
      661 ttcataacta accaactttc tacaatttat aagtttatca tttactattg taccataaaa
      721 ttacctaaaa tctgtgaatt tcacttggaa atattaaaga tattctctaa gagcgcttgc
      781 tatatccgaa aaatcgtagc cctttcgtgc taaaacttga gttaaacgct gcttcagttc
      841 gtatccttca tactttcgag catacttact atattgttta tcaagttcct tgaagatgag
      901 ttcttgagtc gtttcttggt caacttggct atctaagtcg tcaaaggcaa ttttagcatc
      961 agaataagag aagcccttgt tagtcaagtt ctggataatc ttatcttgca gggcacgaga
     1021 tggaagtttt ccctcatatt ttttcaatag tttattagct acacgttgag caacttcaga
     1081 aaaatcaaat tctttcaagt tctcttctat agtagatttt gaaatccctt tttgagctag
     1141 tttctgagtc agcacataag gacccttgtc tcctgaaagt tgattggtat tgatgatagc
     1201 ataagcgtac tgaccatcat taatccactt atcttcttta agattagcaa taacttgaga
     1261 aacgatgttt ttatcaatat cgtatttttt cagatattct ctgacttctt tttcagtgcg
     1321 tgctttaaag gataagtggt agagagcgag attcttacca taagaaaatt gagcaaagtc
     1381 ttgaatctct ttcaattcct cttcgcttat caccttatct ctcgataaca taaaacgaac
     1441 aattgtatct tcggtgatat agcatttgtc gccattatca agctccatca gatagagtct
     1501 ttttttcttt tcaagttttg tgattttcat agctctatta taactcaaaa tgtgataaga
     1561 taggggtatg aatctgaaag tgaaacaaaa aataccatta aaaatcaagc gcatgggaat
     1621 taacggtgag ggaatcggct tttaccaaaa aacattagtc tttgtaccag gagctctcaa
     1681 aggcgaagat atctattgtc agattacttc tattagacgc aactttgttg aagcaaaatt
     1741 actgaaggtc aacaagaagt ctaaatttcg aattgtgcca tcttgtacta tttataatga
     1801 atgcggaggc tgccaaatca tgcacctgca ttatgataag cagctggagt tcaagacgga
     1861 cttacttcat caagcgctga aaaaatttgc tcctgcagga tatgaaaatt atgaaattcg
     1921 tccaactatt ggaatgcagg aaccaaaata ttacagagct aagttacaat ttcagacccg
     1981 aaaatttaaa aatcaggtca aggcgggctt atatgcacaa aactctcact atttagtaga
     2041 gttgaaagac tgcctggtac aagataagga aacccaagtg attgctaatc gcttagcaga
     2101 attacttact tatcaccaga ttccaatcac ggatgagaga aaagttctag gtgtccgtac
     2161 tattatggtc cgacgcgcga gaaagaccgg acaggttcag attattattg ttacaaaccg
     2221 ccagcttaat ttaactcaat tggtaaaaga gttggttaaa gatttcccag aagttgtgac
     2281 agtagctgtt aatacaaata cagctaaaac cagtgagata tatggtgaaa agacagagat
     2341 tatctggggg caagagagta ttcaagaagg tgtactcaat tatgaatttt cactatcccc
     2401 tcgagctttt tatcaactaa atcctgagca aacagaagtc ctctatagcg aagcagtaaa
     2461 agcgctggat gttgataaag aagaccattt gattgacgct tattgtggag ttggaacgat
     2521 tggatttgcc tttgcaaaga aagtaaaaac actcagaggt atggatatta ttccagaagc
     2581 tattgaagat gccaagcgaa atgctaaaag aatgggattt gacaatactc attatgaagc
     2641 tggaacggca gaagagatta ttcctcgttg gtacaaggaa ggctaccgag cagatgcttt
     2701 gattgttgac ccaccacgta caggtctgga tgataagtta ttagatacta ttcttactta
     2761 tgtaccagaa aaaatggttt atatttcttg taatgtttcg accttggctc gtgatttggt
     2821 acgcttagta gaagtctatg atcttcatta tatccagtcg gtcgatatgt tcccacatac
     2881 agctcgaact gaagctgttg taaaattaat aaaaaaagtt taaaaaaggt gttgacaaaa
     2941 cataaaaag
//
LOCUS       DAVMAH010000099         2660 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVMAH010000099 DAVMAH010000000
VERSION     DAVMAH010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2660
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.100"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            158..1378
                     /locus_tag="VYO94_002005"
     CDS             158..1378
                     /locus_tag="VYO94_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HEV1760569.1"
                     /translation="MKKILLSTVALLSLVASLLANNPVSAQESSSQATYSKSSGSWIK
                     SGNRWWYKHSDGSYTTNGWEKINGTWYYFDSEGWMKTGWIKEYGKWYYLDDSGAMKTG
                     WCLVSGSWYYLNSSGVMQTGLQTINGKQYYLAAGGAMQTGWHNIGDDTYFFANSGENQ
                     NINRRALVLGETSTRAVPIADVNAMEKVFNNQNFSEVVRFPDRTKSEIIAKMQELFES
                     SSEGDVNYLYFTCHGGRDGRIYIGSDGLAFSGWELASVLKQYKGKFVVMLDCCHAGTI
                     ISKDNTGEGNEGASTEYFDLDEFVSGFSNMDGNEKSGEMIDSKFLVLCSSRGAEYSSG
                     GSLSLATKYWSLGSGWNPLQNSQAYLAADQNNNRRITLNELYTYSREQVLKQNSNQHI
                     EVYPDNSQFVLFKK"
     gene            1391..2572
                     /locus_tag="VYO94_002006"
     CDS             1391..2572
                     /locus_tag="VYO94_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1760570.1"
                     /translation="MKVSKKITLFSLSFAGFVLLTLPQAGKAFELKEDWAFKGGIRYE
                     NGKVSKINNGYEVNIKVLDLPSTSAIEWTVRLNGEKQNTNFLAEERTVSKTEDKGRFL
                     HFYIPYGYRGDIVVEAKSGNEVKTWSTKVVDDVYSDSAKSGYFILDGEQILESSWDSV
                     NESYIATLPTVTSGKTVVAWREKGTLNLIKPGRIARQYNSSGSYVELSPIFETASWLK
                     SNQNWYYQKQGQLVQNSWIKDQGSWYFMDDEGVMFNQTWLHQGGSWYAFKSSGAMISA
                     DWLYDNGSWYYLKDSGSMVTGWLKNGGSWYYLNKSGSMATGWIKDSGTWYYLKNSGSM
                     ATGWVKDSGSWYYLKNSGSMATGWVKDNGKWYYLASSGNMLRNTRTPDGYYVDGSGAW
                     K"
BASE COUNT          888 a          368 c          581 g          823 t
ORIGIN      
        1 aatctttaag gcgaaaattt tttgaaatac gaatatcctt taaaactgct ccgaaatttt
       61 ccataatgtt cctcttccat ttctgcaaaa aataaaacgc ttgtttttta tttatgatat
      121 gattatacaa aaataaaata gaaaggacaa taatatcatg aaaaaaattt tattgtcaac
      181 agttgcttta ttaagcttag tagcatctct gctagcaaat aatccagttt ctgctcaaga
      241 atcatcctct caagcaactt atagtaagtc aagtggaagt tggataaaat ctggtaaccg
      301 ttggtggtat aagcattctg atggttctta tactacaaat ggatgggaaa aaataaatgg
      361 tacctggtac tattttgata gtgaaggttg gatgaagaca ggttggatta aagaatatgg
      421 gaaatggtat tacctagatg atagtggtgc tatgaaaact ggatggtgtt tggtttctgg
      481 tagctggtat tatttaaata gtagcggtgt aatgcaaacg ggactacaga ctatcaatgg
      541 aaaacaatat tatttagctg ccggcggtgc tatgcagaca ggttggcaca atatcggaga
      601 tgatacctat ttctttgcta atagtgggga aaatcaaaat atcaatcgtc gtgctttagt
      661 tcttggtgaa acatcaacga gagcagtacc tattgcagat gttaatgcta tggaaaaggt
      721 ttttaataac caaaacttta gtgaagttgt tcgtttccca gatagaacaa aatccgagat
      781 aattgcaaaa atgcaagagc tttttgaatc ttctagcgaa ggcgatgtga actatcttta
      841 ctttacttgt catggaggaa gagatggaag aatctatatt ggtagtgatg gcctagcatt
      901 ttctggttgg gaattggcgt ccgttttgaa acaatacaaa ggtaagtttg ttgttatgct
      961 ggattgttgt catgctggaa caattatttc taaagataat acaggtgaag gcaatgaagg
     1021 agcctctacg gaatattttg atttagatga atttgtatca ggattttcta atatggatgg
     1081 taacgaaaaa tcaggtgaga tgattgactc taaattttta gtattatgct catcaagagg
     1141 tgcagaatac tctagtggtg gatcattaag tttagcgact aaatattggt ctttaggttc
     1201 aggatggaat cctctacaga attcacaagc atatttagca gcagaccaaa ataataatcg
     1261 cagaatcaca ttaaatgaat tgtatacata ctctcgtgaa caagttttga aacaaaattc
     1321 taaccagcat attgaagttt atcctgacaa cagtcaattt gtgttattta agaaataagg
     1381 gggcaataaa atgaaagtat caaaaaaaat tacactattt agtttgtctt ttgcaggttt
     1441 tgttttattg actttacctc aagcaggaaa ggcttttgaa cttaaagaag actgggcatt
     1501 taaaggtggc attcgatacg agaatgggaa agtcagcaaa attaataatg gatatgaagt
     1561 aaatattaaa gtgttagatt tacctagtac tagcgcaatc gaatggacag ttagattgaa
     1621 tggagaaaag caaaatacta acttcttagc ggaggaaaga actgtatcta aaactgaaga
     1681 taagggacgt ttcttgcact tttatatccc ctatggatat cgtggggata ttgtagtaga
     1741 ggctaagagt ggaaacgaag tgaagacttg gtctactaag gtagttgacg atgtttattc
     1801 agattctgct aagagtggct actttattct cgatggggaa caaatcttag aaagttcatg
     1861 ggattccgta aatgagtctt atattgcaac gcttccaact gtaacatcag gaaaaactgt
     1921 tgttgcttgg cgtgaaaaag gaactcttaa tttaattaaa ccaggaagaa ttgctcggca
     1981 atataatagc agtggatcat atgtagaact ttctccaatc tttgaaactg ctagttggct
     2041 aaaatcaaac caaaactggt actatcaaaa acaaggtcaa ttagttcaaa attcttggat
     2101 caaggatcag ggaagctggt actttatgga tgatgaaggg gttatgttta atcaaacatg
     2161 gctacaccaa ggtggaagct ggtatgcctt taagtcatca ggagccatga tttcagctga
     2221 ttggttgtat gataatggtt cttggtatta cctaaaggac tcaggttcta tggtaacagg
     2281 atggcttaaa aatggaggct cttggtatta cctaaacaag tcaggttcaa tggctacagg
     2341 ttggattaaa gatagtggaa cttggtatta tctaaagaat tcaggctcta tggcgacagg
     2401 ctgggtgaaa gatagtggct cttggtatta tctaaagaac tcaggttcaa tggcaacagg
     2461 ttgggtcaaa gataatggta agtggtacta tctcgcatca tctggtaata tgcttcgcaa
     2521 tacacgcaca ccagatggct attatgtaga tggcagtggc gcttggaaat aaatttttaa
     2581 aagagaaaat ctactgagaa ggtagatttt ctttttagtt aatgaatata gaataaagta
     2641 gatcaggact ggtctatttt
//
LOCUS       DAVMAH010000100         2625 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVMAH010000100 DAVMAH010000000
VERSION     DAVMAH010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2625
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.101"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..574
                     /locus_tag="VYO94_002007"
     CDS             <1..574
                     /locus_tag="VYO94_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1760571.1"
                     /translation="KIPSRLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLN
                     RSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIA
                     LARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIIAHRLSTIKDADIIFV
                     MKGGKIVESGNHKYLMTLGGEYYSLYTKRK"
     gene            587..757
                     /locus_tag="VYO94_002008"
     CDS             587..757
                     /locus_tag="VYO94_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760572.1"
                     /translation="MKKENEYVILTIASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(1253..2599)
                     /gene="gdhA"
                     /locus_tag="VYO94_002009"
     CDS             complement(1253..2599)
                     /gene="gdhA"
                     /locus_tag="VYO94_002009"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV1760573.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFNAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          847 a          457 c          508 g          813 t
ORIGIN      
        1 aaaaatacca tcaagattat ataagattga tacaggaaaa gttttatttg atggtgtaaa
       61 tattaatcaa atagataaaa aaatattaag tcaaaattta ggagtagttc cacaggattc
      121 gtttttattg aacagaagta ttcttgataa tataacttta aagcacgaag ttacttcaca
      181 aaagatagag gaagtttgta aagcagttca aatctatgat gaaatcatgg ctatgccgat
      241 gaaatttaat actatcatct cagagatggg gtcaaatatt tcaggtgggc aaaggcaacg
      301 gatagcactg gcacgtgcat taataaataa tcctagtatt gtaattttag atgaagcaac
      361 tagtgcatta gacactatta atgaggaaag aataacaaag tatatacaaa gtcagggttg
      421 tactcaaata attatagctc atagattgtc aacgattaag gatgcggata ttatttttgt
      481 aatgaaaggt ggtaagattg ttgagtcagg aaatcataag tacttaatga ctcttggtgg
      541 agagtactac agcttatata caaaaaggaa atgaggtgta aagaaaatga agaaagaaaa
      601 tgaatatgta attttaacaa tagcctcact aggggtgatg attggaatag tgtttgcaat
      661 ttttttagat tttccagttg aatatggtat ttctttaggc ttgttgaatg gaatagtatt
      721 gggttcgctg attgtttaca aaaacaataa gaattaagca taattttttg ctgtaaacta
      781 aggagtagag atggctatag ttgaaattat aactctaaca aaaagcttta aagatattga
      841 agttattcat aacacttaaa taatagagca actacagtag tagcttaaaa acatgattaa
      901 atcgctattc ttaggagtag cggtttttct ttttgtttaa tactctttga aaatctcttc
      961 aaaccacgtc agctttgcct tgccgtactc aagtacagcc tgcggctcgc ttcctagttt
     1021 gctctttgat tttcattgag tataaaaagg gttaagtaag tatagtaaat tgaaataaga
     1081 tatgaacaaa tcgattagaa aagtcaaatt aatttctaga agtatgttag aaattggttt
     1141 gaattccgca atcaatttgt tcagttttta tttcatttaa ttagaatttc ccaactgtct
     1201 aactcaacta aaaatcccca atcgtagtga ttgaggatta agcaaataaa tcttaaacaa
     1261 taccttgggc aatcatagcg tttgctacat tttcaaaggc agcaatgtta gctcctgcaa
     1321 ggtagtcttt atcaagaccg tatgtttctg aagtcgtttt agctgtgttg aagatgtttg
     1381 tcatgatgtc tttgagacgg ccatcaactt cttcacgagt ccatgagagg cgaagactgt
     1441 tttggctcat ttcaagagct gaaacggcta caccaccagc gttggcagct tttgcaggtc
     1501 cgtagaagat accattttct ttgtaaactt tgatggcatc aaggtcgctc ggcatgttgg
     1561 caccttcaga tacacagata acgccttgag caaccaaacg tttagctgct tcaccgttga
     1621 tttcgttttg agtggcacat ggaagagcaa tgtcatagtt tccagcgtaa gtccatacag
     1681 taccttcgtg gtaggttgca gttgcttttt cagctgcata ctcagtcaaa cgagcacgac
     1741 gtttttcttt aacatcaacc aaaagatcga agtcgatacc attttcatcg atgacataac
     1801 catttgagtc agaaacagaa ataacagttg caccgagttc agttgctttt tgaagagcat
     1861 attgagcaac gttaccagaa cctgaaataa cgactttctt accagcaaag ctgttaccgt
     1921 tagctttgag catttcttca gtatagtaaa ccaaaccgta accagttgct tctggacgaa
     1981 tcaagctacc accaaatcca agaggtttac cagtcaagac accagcatta aattggttaa
     2041 gacgtttgta ttgaccgtaa aggtaaccaa tttcacgtcc accaacaccg atatcaccag
     2101 caggtacgtc aagtgatggt ccgatgtgtt tttgcaattc agtcatgaag ctttggcaga
     2161 agcgcatcac ttcagcatct gttttacctt taggatcgaa gtctgatcca cctttacctc
     2221 caccgatagg aagtccagtc aagacatttt taaagatttg ttcaaatccg aggaatttca
     2281 agatcccttg gtttacagtt gggtggaaac gaagtccacc tttgtatggt ccaacagctg
     2341 agttgaattg aacacggtaa ccacggttta cttgaatttt tccatcacgg tcaacccaag
     2401 gaacacggaa agaaaccacg cgctcaggct cagtaatacg tgccaagata ttttcttcga
     2461 tatactcagg gtgtttttca aatacaggtt ccaaagtgtt gaaaaattct tcaacagctt
     2521 ggaggaattc agcctcgtgc ccgttacgag ctttcacagt ttcaaacacg ctttggatat
     2581 attctttagc agatgtcata tcgttctcct tttattgtca tattt
//
LOCUS       DAVMAH010000101         2600 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVMAH010000101 DAVMAH010000000
VERSION     DAVMAH010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2600
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.102"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..934
                     /locus_tag="VYO94_002010"
     CDS             <1..934
                     /locus_tag="VYO94_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEV1760574.1"
                     /translation="LPTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPIGFS
                     NKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSISTHST
                     ANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPR
                     IGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERK
                     PKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFE
                     LFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            1329..2192
                     /locus_tag="VYO94_002011"
     CDS             1329..2192
                     /locus_tag="VYO94_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1760575.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQGQMAETYRRLNAIVIKNALHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKSGFLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGNNQKEIENFIQSLQVLENPQLTSLFE
                     LRLQQYKALID"
     gene            2483..2587
                     /locus_tag="VYO94_002012"
     CDS             2483..2587
                     /locus_tag="VYO94_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011225312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1760576.1"
                     /translation="MENTEFSLELDVTEVATEQDYVSSGVTSTGCCKN"
BASE COUNT          903 a          385 c          491 g          821 t
ORIGIN      
        1 gcttccgaca gattatgatg agaaaattgg tagttttaat acatatgaaa tcgaacaaac
       61 ggtatcgaag attctgaggg taaaacctaa tggaaagatt attttaaagt caacagttcc
      121 gatcggcttt tcaaacaaat taaaaaggct gtttgataca aaaaatatca tttttgtccc
      181 tgaatttttg agagaaggtt gttctatata tgataattta tatccaagtc gcatagttgt
      241 tggagatgag acagttgaag gaagaaaaat tgcagagttg ttcctttcga ttagtactca
      301 tagtactgcc aatattaaaa atgttatgtt agtttctcct actgaagcag aagcaattaa
      361 gcttttttct aacacattct tagctctccg tgttgctttt tttaatgaac tagattcttt
      421 tgctgagagg agaagtttaa atgctgaagt tgtaataaaa ggtgtttgtt tagatccaag
      481 aattggaaat ttttataata atccttcttt tggatttgga ggatattgtc ttcccaaaga
      541 tactaaacaa ttaaaaaaag aatttataga aataaatgcc ccagtgatag aagcgattga
      601 tatttcaaac acaaatagaa aacagttcat agttaaacaa atattggaac gaaagccaaa
      661 gatagtagga atatataaat tggggatgaa atataattca gataattaca aagagtcagc
      721 tattttaagt ataattaatg aactattgat tgtcggtata aaaattttag tatatgaacc
      781 aaatttaaac gttagtatag ataacgtaat ttttgaaaag aattttgaac tatttacaaa
      841 acaaagcgat ctaattgttg caaatagatg ggataggggc cttgaagctt ataaagataa
      901 agtttacaca agggggatct ggataagaga ttaactattg atattaaaaa ggcaataatt
      961 tataaaattt gtacaaaaaa atgttaaatt ttcacatttt catagtatac tgtttaatag
     1021 aaagtaggtt ctttgtaacc gctccattat aaaatccttt cactcttccg gtatactatt
     1081 aggaaaaaca taactggagg atattttgag ctcacacctc atcgttccag tggctgttcc
     1141 ccaagctcgt gtactgccca aaaaagttag acattctatt tagaacgagg attgagttct
     1201 gtattgtaca aggctcggtc cttttagagt cagcttaagg ctggcttttt taatcaccaa
     1261 agtgtcagaa tgttttgaca aatgaacaca aataatgata taatatgcaa aagctaggag
     1321 gtggtaggat gattgaaaaa atggaactgg gggaatttta caaggaattg cgtttggcga
     1381 gaaagctcaa gcagtcagat gtggcttgtg ctggactaac agcttctcag ctatccaagt
     1441 tcgaactagg gcagtctatg ctgtctgcgg ataagctcat actagccatc caagggatca
     1501 atgtgacctt tgatgagttt gggcacaagc tcaacaacta tcaagaatct ccacatatgc
     1561 agattggtag aaaggttgtg gatcgctttg ctcatcaaga tatagctggc ttagagcaac
     1621 tgttggagga agtcgagcaa ggacagatgg cggagaccta tcgtcgtttg aatgctattg
     1681 tgattaaaaa tgcactccat tccttagata aaagctatcc gctagcagag gaggatagcg
     1741 agtttttgac tacctacctc tatgctattg agtcttggac ctggtttgaa ctctatcttt
     1801 tttgcaatac catgcccttc ttgagcaatc aagatctgat ctttttatca acctctttgc
     1861 ttgaaaaatc caaggaattt aaagagttgg tacataatag actgtatatg aaaagtggct
     1921 ttctgaatat tatatcagag ctcatggagc gcaagctttt ctcctatatc ccaatctttg
     1981 aagcagagct ggagagcatg ttgcgtccgt acgatgtttt tgaaaaagta ttgtggcaat
     2041 ttttaaagaa aatgagtatt ttccttcaaa ccaaaggaaa caatcaaaaa gagattgaaa
     2101 attttatcca atctctgcaa gtattagaaa atccacaatt aacatccctt tttgaactac
     2161 gcttacagca atacaaagca cttatcgatt agttagaaat gggaaaaaga taataatctc
     2221 agcaacgatt gtcaataatg ttaaaacttg tttcttcata tgacttccac tcctcattag
     2281 taataacttt attataccag ggaaatgatc aaatctacta aaatcgcaaa tgtgaaattt
     2341 ttataagaaa aaatatcaaa tatgcgattt tctaaaataa gccaattttc gtgttatact
     2401 gtacttataa agcacttgaa gcaaatccta ggtcgcagaa gtggtttata agtaaaaata
     2461 attggaggag gaatcgttta ttatggaaaa tacagaattt tcattggaac ttgatgtgac
     2521 tgaagttgca actgaacaag attatgtttc tagtggtgtt acatctacag gttgttgtaa
     2581 aaactaattt aataattgat
//
LOCUS       DAVMAH010000102         2515 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVMAH010000102 DAVMAH010000000
VERSION     DAVMAH010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2515
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.103"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..260
                     /locus_tag="VYO94_002013"
     CDS             <1..260
                     /locus_tag="VYO94_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760577.1"
                     /translation="VGFLGIIYDNEALRDLSKQYLNKNISELQDGSFEGGIQDAVASK
                     QIVVINEFIACLNSRCMPSQYDRFFYKDRPYIFSRKSPIKG"
     gene            575..1552
                     /locus_tag="VYO94_002014"
     CDS             575..1552
                     /locus_tag="VYO94_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760578.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGVAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLNKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            1929..2303
                     /locus_tag="VYO94_002015"
     CDS             1929..2303
                     /locus_tag="VYO94_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV1760579.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
BASE COUNT          855 a          318 c          447 g          895 t
ORIGIN      
        1 aggttggatt tttgggaatc atttacgata atgaagcatt aagagatttg tcaaaacaat
       61 atttaaacaa aaatatttcg gaattacaag atggttcttt cgagggcggt atacaagatg
      121 ctgttgcctc taaacaaata gtagttataa atgaatttat agcttgttta aattccagat
      181 gcatgccatc ccaatatgat agattttttt ataaagatag accttatatt ttttccagaa
      241 agagtcctat taaggggtga aaatttgtta catttggatt aacaagtgtc ctagagatta
      301 gaaataactc tagtatagct agatattttt gagtaactag aaatatcatt agtctaccca
      361 tatgattgcc agaaaagatg gctgatgaat cttatttata ctgttgcagt aggcattgtc
      421 taggataaat aagctatctt gatgggggag attggaataa ttttagtaga aacattaaag
      481 gattatggac aagtagcgca ggattaggtg atgcaatgtg ttaagttggc ttggtgttag
      541 cagtagtatt atttaacaat ggaaagtaga ctaaatgaaa aataaacgtt atttttttga
      601 cacaatttta ataattttac tgcttataag cacgatattt tgtgtcagcc cagtatttat
      661 aaaattggac atcttaggaa ctccctctca tgccatctta acctttgtat tggcgatacc
      721 gttattctat attttgtctc aatgcttaca tactttgcta ttactagttt cctcaatctt
      781 ttgtaaatta agaccaattt atttttattt tatatttgtg atcattatag gagctaggaa
      841 atactatcga attctctttc accaactaat gggatttagt ccaggagtag cagtgtttta
      901 taaggagagt caaacaacta agaatctgtt taaattttac tacttcttgt actttacaac
      961 actaatttca tactattttt tctttacttt tgtgtatgac aaaccgttgc ttttgcctct
     1021 tattccattt tctattatca tagcattagt acaaaaactt tatagaattg agaatcaaca
     1081 attatttctg ttaaaatcaa aggtactaac aatactggaa tctaagaaga attgtgagtt
     1141 taatcttcag gattatcatg aaatttggaa attgcaatca aaatctgagt tgccatgcgt
     1201 ggctttatct tatatcagtt tgatcaagcc atatctttca gagagcgtgc gtgaacaaat
     1261 tgatttatta gaagttaagc gatttaaaaa aataaatcat ccaatatcac tttatggtat
     1321 gttggatgtt ataaaattaa atctatattt acggcattat aatgaaaaaa ataaatatga
     1381 atcaatgtta aataaaattt tagaggtaag accagacttt gttttaatcg agcagaatat
     1441 tgatgatagt ttaaatagct cgcaaccatt atctttatct ttagccattt cagaaatcca
     1501 acttttgctt gaagtgtata tggggatcaa acatgtttca attaggagat aaaaccagaa
     1561 taatatttgc cattataggg gcaagttgca tattagtcag tatgtatctt attccactta
     1621 ttaaaactga gaataaattt tgggaaatac ttttatttat attaggtgta ttgctaattg
     1681 gaattgcgtt attaagtcaa aaaaaataaa ttttgaaata gtattagtga gttcgcaatc
     1741 atttattgct agtggtttag aactgttaag tttcaaacaa taattgattt taaaccttag
     1801 gtaacctata aaaacaaata aggtagagaa aggatatctt atctaggtag ctaagtgata
     1861 aaaacacagt cgtctatcac ttgttaggaa actatcctaa ctatgcttaa taaaaaagga
     1921 gaaaataaat ggaactcgta ttaccaaata attatgttgt tcttgagcaa gaagagatga
     1981 tgtatcttga tgggggattt tctattccga gatggcctgt tgcaacagcc attaatatag
     2041 cttttaatgg tgttttaggt ggaggagcaa tcagtctagt tagaaattat attcgtaatt
     2101 atggtttgcg gcgagttaca agcgcaattg ctggagcagc tgcaagatat gttggggtac
     2161 gagttgcaaa tagagtggca ggatttgcac tgtctgctat taatggattt gcagcttgga
     2221 tgtcaattgg cgatgctatt acaacaatct gggccaataa tgatgtaaat aggagagacc
     2281 caaatttaaa cgccttgtgg taactagata tgggtattaa aatggaaaaa atttttgtta
     2341 ttattttttt tgtatgtcta tttatatcat ccataacttt tttagcctat gattttgtta
     2401 gcgaagaaat aaaaaagttg attatttgga ttaatgtcgt ttttttgatt ttaatcatag
     2461 caatgatgat ttatccaaaa ttaagaaaat gataaggaca ctgtaaaatt atgat
//
LOCUS       DAVMAH010000103         2474 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVMAH010000103 DAVMAH010000000
VERSION     DAVMAH010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.104"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(<1..744)
                     /locus_tag="VYO94_002016"
     CDS             complement(<1..744)
                     /locus_tag="VYO94_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760580.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLIQNQSKVDLDIFYKVLPLLYK"
     gene            complement(1625..1837)
                     /locus_tag="VYO94_002017"
     CDS             complement(1625..1837)
                     /locus_tag="VYO94_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760581.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQTK"
     gene            complement(1845..2216)
                     /locus_tag="VYO94_002018"
     CDS             complement(1845..2216)
                     /locus_tag="VYO94_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEV1760582.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
BASE COUNT          915 a          459 c          300 g          800 t
ORIGIN      
        1 tttataaagc aaaggtaaaa ctttataaaa aatatctaag tcaaccttac tctgattctg
       61 aatcaagtag gagtcaagca aattttcaaa aatagctaac aatatgattg gtgtaaagtt
      121 tttgtattca catgtcaagt attctgagta tcgtgcagat gatatttctt ttatataact
      181 ttttgaaagc aagatttttt caaattcatc atctattatt aatcttctat ttccaatcca
      241 aacggtatta ccacccaaat aagattgtgc aaatagcaat atgtaagaaa atatgaacgt
      301 aaatactgaa agaggtagaa ttctatgcgt aaaaaaatag acgataatag tagccaggag
      361 taaagatatc tctcgtgaca atcgaattct tttcagcatc ttttttaaca gtccgtaagg
      421 ttgtccttgg caatattctt gaactaaatt aatcggaatg acatctctca ccatttctgg
      481 aaagtagagt aagtttatag gttgaaatct ccagctccca tcataagtaa atggatatag
      541 aaccaaatac ttaaaagatt tttttcttat aaacttaatt atcacaatat gaatgactgt
      601 tgcaatgaag tatattaaat ataaaagtaa aaccgccatc aatatactta caaaaatccc
      661 cttggactca atcaatggaa aataaaatat tgcaactaga agcgaataaa gtcccgctaa
      721 taaatatttc tgatcatctt tcattcaaaa caccatatta tttactaaga atacatcaat
      781 acaatagagc aactctgtaa gtcaatattt gataaagcaa agctttaacc ccttccccag
      841 acgttagctt ttcttcaacc cactacagtt gacaaggagc ccaaattatt gataaaaact
      901 ttagtcatca tcgtctctat aaaaatattt tctatacact cttgataata ccaaaattaa
      961 tgccaatatc ataccaagag ctataataat agaatttatt agatttattt tagtatatcc
     1021 aatcactagt ccaataattg gactagcaga catgcttaga tataataaaa ataacaaaaa
     1081 atgaatttca ccaattcctg caaaaaaatg tttcatagct atagttttac gcccataaat
     1141 acccatcaaa tttaccgtct acgatatcta aaccatatgc aatggctcct cctaatgaga
     1201 agacttcagc aacagtagcc gcaatattaa gagcattagt aatagttgcc atactaactc
     1261 caccaatata tcttgttata gcacttagtt acctagataa gatatccttt agcttgcttc
     1321 caaaatttaa gtctacacct ataatatgag ttcatattag tactgctaaa tcctatctat
     1381 agtaatgtca aacacctaaa tcaagtcatc tctccaattc atccaagaaa tgaagaaagg
     1441 caaaaaatct ttaaaataag aaaagtgcat attatcaggt gttcaaaaat cttgataata
     1501 tgcgttatat aatagaaaaa tttactcaat ttcattttca aattgagttt tttcccagcc
     1561 tcatttttaa tttatatctt caatagaatc taatgaccga gctactgtat tacacagatt
     1621 aatattattt agtctgtaat ttttttaaaa aacttaatag taaatttgct ccactgattg
     1681 ctatcaatat ttcaattggt aaaaaatagt aattccaaat aaaatgagaa atcagcaatg
     1741 atagaaaaat aacaatatca attttcctgt tgttgacata ctctgtaatt ttatgataca
     1801 ggaatgcaac aataactgaa attaaaacaa tcaacataag attattaacc tattctcaat
     1861 tgattatcac gtcgcccatc ccagccatca ataatattgg taaaaatcca atcagctcca
     1921 gcaccaattc cagcagatgc aatacttcta ataacagtat ttgcaaaagc atttccaata
     1981 tgaattccta atactcctaa acctttaaca atcccagcta ccagtgcgga gcgtaatcca
     2041 taagatgcaa gaactagttg aaggcctcca cctcctgctg ctgctaatgc tgcatatgct
     2101 gcaccagtaa tggctcctgt aattgcccac ctgggtatat atatagcccc cccatcaagg
     2161 tacatcatct cttcttcatc aatcacaaca taattatttg gtaatacaag ttccatttat
     2221 tttctccttt tttattaagc atgcttagga tggtttccta acaagtgatc gcaggctttg
     2281 tttagttacc taaattagac ttccttcctt tatcttattt taaatattta aaaccagtta
     2341 ctgcttgaag cttaacagtt tacttaattc aaataacagc taatcactga ttccctgatt
     2401 ttatcaaata tactaataac aacaattgtg atacgatcat cattataaga acaacattta
     2461 acgaatcaaa gttt
//
LOCUS       DAVMAH010000104         2416 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVMAH010000104 DAVMAH010000000
VERSION     DAVMAH010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2416
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.105"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            12..>2416
                     /locus_tag="VYO94_002019"
     CDS             12..>2416
                     /locus_tag="VYO94_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011225313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HEV1760583.1"
                     /translation="MLMVANPRFFNELTKEKIYQNSTFRNYAKRSLTRATPFGLFSSV
                     GVGSFSKVSYPQQIRENYSKKVSVSGEWISSLCMMLENEDSVLLQLHLQWNQKVLELS
                     DKYQLNNINYWGVSEQSRDILIKKTALLEFIKKLTYKSEVSVLDLVQEIQTKSPNLET
                     QKIIDYLRNLIISEFLFTNLRKVVINHNCLDNLIYILSSINEQTKLTTDLLQLKSCIE
                     KYSKSELGEGILQYAEICEKMSHIFNEEKQRYLKVDLVNSYDSLLPKDLKKTLEDFVN
                     FISRINLGKDYRNKELISYTEKFVEKYGEYVEVPIKQLLDSKLGLGIPKQNLEPYSIL
                     SSVAEQTFLSYLSKEIFKAVKNNKKEIDISNIPPELLYPNLDRFAVNQFELYCEMKNF
                     GEQPVISIVPNTGSDMIGKSIGRFASYFLNSNIELDSRVDNVELIEFPSDNKNLNVMS
                     SHHGHSKKLLLSYEDDFDIDSLELDFLVVGVERVNEHYKLYFRDLRTDLIVNFVTTSM
                     LNHKSIGVFSHLARFLLTVSLEWQDNPFSLFRVIENLDFLPYIPRIKYKNIILSEEKW
                     ILSDVDKKDMSTISQWKKFFDVPSLLYFHKDDERLLIDLKNSLDVQWILKQNVDKLHF
                     TRFDKIDGKNCEFIFGFENPRNSVYPHSVSEKTVRRIENDFYKDYVKTFSSDWIYFKL
                     YGINSSTMPELRENLLIFTDELLAEKLVSDFHFVNYNDGGDGSIRLRFKIMNEDDFEK
                     LRYRIIHWIDFLLNHYFCKDVSFNLYEREVERYGGIGFLTVCERIFSIDSYLVLKLFS
                     KKV"
BASE COUNT          859 a          262 c          441 g          854 t
ORIGIN      
        1 tatttcaaga gatgttgatg gtggcgaatc cacgattttt taatgaatta actaaggaaa
       61 aaatatatca aaattctacg tttagaaatt atgcaaagag gtcgcttaca agagcaactc
      121 catttggatt gtttagttca gttggtgttg gttctttttc aaaagtttca taccctcaac
      181 agattagaga gaattatagt aaaaaagtgt ctgttagtgg agagtggatt agttcgcttt
      241 gtatgatgtt agaaaatgaa gattcagttt tattgcaatt acatttacag tggaatcaaa
      301 aagtactgga gctatcagat aagtatcaat tgaataatat caactattgg ggtgtttccg
      361 agcagagtag agatatactt atcaagaaaa ctgccctttt agaatttatt aaaaaattga
      421 catataaatc ggaagtaagt gtattagact tggtacaaga aattcaaact aagtctccta
      481 atttggagac acagaaaatt attgattatt tacgtaattt aattatcagt gaatttttat
      541 ttacaaactt acgaaaggtt gtaataaatc acaattgttt agataattta atttatattt
      601 taagttctat taatgagcaa acaaaattaa ctactgattt gttacaactt aaatcatgca
      661 tcgagaagta ttcaaaatca gagttaggag aaggtattct tcaatatgct gaaatttgtg
      721 aaaaaatgtc tcatattttt aatgaagaaa aacagcgcta tctgaaggtt gacttagtga
      781 atagttatga ttcgctatta cccaaagatt taaaaaagac attggaggac ttcgttaact
      841 ttatttcgag aattaatctg ggtaaagatt atcgaaataa ggaattaatc tcgtacacag
      901 aaaaatttgt cgaaaaatac ggagagtatg ttgaagttcc tattaagcaa ctactggata
      961 gtaagttagg gttggggata ccaaaacaaa atttggaacc ttatagtata ttatcaagtg
     1021 ttgcagaaca aacttttttg tcttatctaa gtaaagaaat ctttaaagca gtgaaaaata
     1081 ataaaaagga aattgatata tcaaatattc cgcctgaatt attgtatcca aatttggata
     1141 gatttgctgt gaatcagttc gagttgtatt gtgaaatgaa gaattttgga gaacaacctg
     1201 ttatatcaat tgtgccaaat actgggagtg atatgatagg aaagtctatt ggtagatttg
     1261 cttcatattt tctaaattct aatatagaat tagattcgag ggttgataat gtagaattaa
     1321 tagaatttcc aagtgataat aaaaatttaa atgttatgtc ttctcaccat ggacattcta
     1381 aaaagttatt actatcttat gaagatgact ttgatattga ctcgttagaa ttagatttct
     1441 tagtagtggg tgttgagaga gtgaatgagc attacaaact atattttaga gacttacgaa
     1501 cagacttgat tgttaatttt gtaacaacct caatgctgaa tcataaatct atcggagttt
     1561 ttagccattt agcgagattt ttgttaacag tttcgttaga gtggcaagat aatccatttt
     1621 ctctatttag ggtaattgag aatcttgatt tccttcctta tattcctaga attaaatata
     1681 agaatattat tttaagtgaa gagaagtgga ttttatcaga tgtcgataaa aaagatatgt
     1741 ctactattag tcagtggaaa aaattttttg atgtacctag ccttctatac tttcataaag
     1801 atgatgagcg tttactgatt gacctaaaga atagtttaga tgttcaatgg attttaaaac
     1861 aaaatgttga taaattacat tttacgcgtt ttgataagat tgatggtaaa aattgcgagt
     1921 ttatctttgg atttgaaaat cctcgaaata gtgtataccc tcattcagta agtgaaaaaa
     1981 ctgtcagaag aattgaaaat gacttttata aagattatgt aaaaacgttt tcgagcgatt
     2041 ggatatattt caaattatat ggaattaact cctcaacgat gcctgaacta agagaaaatc
     2101 ttcttatatt cactgatgag cttttagctg agaaattagt tagtgatttt cattttgtaa
     2161 attataatga tggcggggat ggttctatta gattaaggtt taaaattatg aacgaagatg
     2221 attttgaaaa gctaagatat cgaattattc attggataga tttcctatta aatcattatt
     2281 tttgtaaaga tgtaagtttt aatttatatg agagggaggt tgagagatat ggaggtattg
     2341 gctttttaac agtatgtgag aggatatttt ctattgatag ttatcttgtt ttaaagttgt
     2401 tttcaaagaa agtatt
//
LOCUS       DAVMAH010000105         2397 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVMAH010000105 DAVMAH010000000
VERSION     DAVMAH010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.106"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            47..1591
                     /locus_tag="VYO94_002020"
     CDS             47..1591
                     /locus_tag="VYO94_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760584.1"
                     /translation="MLIYAATINALVLNELIAMNLERFLKLSIYQMIVWCGIIFLDWV
                     VKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHSKSSGTYLSWLNNDVQTLNDQAFKQ
                     LFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLMIMLLVPKIFASKMREVSLNLTNQN
                     EAFLKSSETILNGFDVLASLNLLYVLPKKIKEAGILLKMVIQRKTTVETLAGAISFFL
                     NIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTGVIFTALGELGGQLSSIIGTKPIFL
                     KLYSINPIESNKMNDIEPNEVNRDFPLYEAKNICYKYGDKEILKNLNFCFQRNEKYLI
                     LGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIKKTSYLNMVSNVLYVDQKAYLFEGT
                     IRDNILLEENYTDEEILQSLEQVGLSVKDFPNNILDYYVGDDGRLLSGGQKQKITLAR
                     GLIRNKKIVLIDEGTSAIDRRTSLAIERKILDREDLTVIIVTHAPHPELKQYFTKIYQ
                     FPKDFI"
     gene            1611..>2397
                     /locus_tag="VYO94_002021"
     CDS             1611..>2397
                     /locus_tag="VYO94_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760585.1"
                     /translation="MRFYCEAYEVITEEKKVYFNDIELEVKYSSVEELFIICEKLLDK
                     KKVSFFYVDEKPLRYLLFDYIFLLVLAKKNIPILDGVSNKQVDPTLLHHFSLEIEKNF
                     IDFCYKNMDLILKTQSISLCHREELIIVDVSDDSKFGVFYKRFRTLVDKNNGKYVCVY
                     NFSRVSDILQNWKNYCNRKFSVTFTESQFELFKLLYNQKNFKTISLLFGKKIVAGGII
                     YYSDLTNIEYFCIFWWDSMFGKDSIGKYVYVEEISRCHFLDRNY"
BASE COUNT          839 a          270 c          438 g          850 t
ORIGIN      
        1 aaaaaaattt agtttattaa cgatatttat tgttgctggt caattattgc taatttatgc
       61 agcaactatt aatgctctgg tgttgaatga attaattgcg atgaatttag agcggttttt
      121 gaaattgtca atctaccaaa tgattgtctg gtgtgggata atattccttg actgggtagt
      181 gaaaaattat caggttgaag tgatccaaga gtttaatcta gagattcgaa atagagttgc
      241 cacagacatc tctaactcta cctatcaaga atttcatagt aaatcatcag gaacatatct
      301 ttcgtggcta aataatgatg ttcagacttt aaatgatcag gcttttaaac aacttttttt
      361 agtaataaaa ggaatttctg gtactatatt tgcagttgtg actcttaatc actatcattg
      421 gtcattgact gtagccacct tgttttcatt aatgattatg ctacttgtac caaaaatctt
      481 tgcatcgaaa atgcgagaag ttagtctaaa tttaactaac caaaatgaag cttttttaaa
      541 atctagtgag actatattga atggatttga tgtgttagcg tccttgaatc ttttatatgt
      601 attgcctaag aaaattaaag aagcaggaat tttattaaag atggttatac aaagaaagac
      661 aactgtagaa acgttagcag gcgctattag cttctttctc aatatttttt ttcagatatc
      721 tctcgttttt ttaacaggct atcttgcaat aaaaggaata gtgaaaattg gtactattga
      781 agcaatagga gcactaacag gtgttatttt tacagcgcta ggtgaattag gaggtcaatt
      841 atcctctatt attggtacga agcctatttt tttaaaattg tattcaatta atccaattga
      901 gtcaaataaa atgaatgata tcgaaccaaa tgaggtgaat agagattttc cgttatatga
      961 agcaaaaaat atttgctata agtatggaga taaagaaata ttaaaaaact taaatttttg
     1021 ttttcaacgt aatgaaaagt atttaatttt aggtgaaagt ggaagcggga aatctacatt
     1081 attaaaatta ttgaatggct ttttgagaga ttatagtgga gaattgcgat tctgcgggga
     1141 tgatataaaa aaaacctcct atttaaatat ggtttcgaat gttctatatg tagatcaaaa
     1201 agcttatttg tttgaaggta cgattagaga taatatttta ttggaagaaa attatactga
     1261 tgaagaaata ctacagtctt tagagcaagt tggtttgagt gtaaaagatt ttcctaataa
     1321 cattttagat tattatgttg gtgatgatgg gagattactg tcaggagggc agaaacaaaa
     1381 aattacttta gctagagggc taattagaaa taagaaaata gtattaattg acgagggaac
     1441 ttctgctatc gataggagaa cttcgttagc gattgaacgt aagatattag atagagagga
     1501 tttgactgtc attattgtta cccatgctcc gcatccggaa cttaaacaat attttactaa
     1561 gatatatcaa tttccaaagg attttattta agaatatagg ggagggaaac atgagattct
     1621 attgtgaagc ttatgaggta attactgaag agaaaaaagt atactttaat gatattgagt
     1681 tagaagttaa gtattcctct gtcgaagaat tgtttataat atgtgagaaa ttattagata
     1741 agaaaaaagt atcatttttt tatgtagatg agaaaccctt aaggtatctg ttatttgact
     1801 atatatttct actagttcta gctaaaaaaa atatcccaat cttagatgga gtttccaata
     1861 agcaagttga tccaacgttg ctgcatcact tttctttgga aattgaaaag aattttatcg
     1921 atttttgcta taaaaatatg gatctcatcc taaaaactca aagtatatct ttgtgtcata
     1981 gagaagagct tattattgta gatgtttcag atgactctaa atttggtgtt ttttacaagc
     2041 gttttagaac actggttgat aaaaataacg gaaaatatgt ttgtgtttat aatttcagtc
     2101 gtgtttcaga tatactgcaa aactggaaaa attattgcaa tcgaaaattt tcggttacgt
     2161 ttactgaaag ccaatttgaa ttatttaagc ttttatataa tcaaaaaaat tttaaaacaa
     2221 tttcgttgct atttggaaaa aaaattgttg ctggaggaat tatctattat agcgatctta
     2281 ctaatataga atacttttgt attttttggt gggatagtat gtttgggaaa gattctattg
     2341 gaaaatacgt atatgtagaa gagattagta gatgtcattt tttagataga aattatt
//
LOCUS       DAVMAH010000106         2360 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVMAH010000106 DAVMAH010000000
VERSION     DAVMAH010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2360
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.107"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(<1..203)
                     /locus_tag="VYO94_002022"
     CDS             complement(<1..203)
                     /locus_tag="VYO94_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760586.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNKAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLV"
     gene            complement(217..930)
                     /locus_tag="VYO94_002023"
     CDS             complement(217..930)
                     /locus_tag="VYO94_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV1760587.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1327..1557)
                     /locus_tag="VYO94_002024"
     CDS             complement(1327..1557)
                     /locus_tag="VYO94_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEV1760588.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAIKC"
     gene            complement(1979..>2360)
                     /locus_tag="VYO94_002025"
     CDS             complement(1979..>2360)
                     /locus_tag="VYO94_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1760589.1"
                     /translation="RNKNGQADTNQTEKPNEEKPQTEKPEEETPREEKPQSEKPESPK
                     PTEEPEEESPEESEEPQVETEKVKEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLL
                     FGTQDNNTIMAEAEKLLALLKESK"
BASE COUNT          714 a          463 c          380 g          803 t
ORIGIN      
        1 ttgactaatg atggagattt ccaagtaaaa attaaatcgc cagagaaatt tttcttatca
       61 aaaaacttaa aaagagattg ataaatacta tttgctaatt gacaagtgtc agatgtaaat
      121 tcataattaa cagctttatt aaaatcaact tcagacattt caatgtactc ttcaatagta
      181 atattagctt tttttgtagt cattagctaa tctcctttaa aatgtgatct tttcaagaat
      241 atttttatct aaacaatcca gcaagtcttg gtaagaatag acttcgtaag tcggctgggc
      301 ttgtgtgtga ttttcgaggt gatgaggatt ataccagata gtgtcaatcc ccgcattatt
      361 gccaccttga atgtcggcgg ttagagaatc tccaatcatc agcgtctttt ctttactaaa
      421 tccagcaatt tgctggccaa tcttttcata aaagagagca tccggctttt gagtttgcaa
      481 ctgttctgag ataaagactt gattgaaata aggtactaga ccagattgag ccaaacgtcc
      541 tgtctgaatg gcagtaatgc catttgtcgc agcatacaag ttataatcac gctcaatgag
      601 gctgtccaag agatcatgag cgcccgatag tgtttgtccc tgctgggcga ggtaaaattg
      661 gtaacgctgg gcaagaaaac taccgtcttt ttcctgtcca aaatgagcaa ataaacgaga
      721 aaatcgcgtg ttaaccagct cttgtttact gattttcttc agctccaagt ctttccagag
      781 agccttgttc ataggaacgt aataatcttt ataagcctga atatccgcaa ctccttcttc
      841 ttttagaagt tgggtcaaag ccacatcctc agcagcatca aaatcaagaa gagtgtggtc
      901 gaggtcgaag agtagaaatt tgtagaacaa tttgaggttt tcctttctga aaattcatta
      961 agaacattat atcataaagc acctcataca attaactaat ttaatcactt aaaaaaaatt
     1021 cgaacacttt ctatacaact gacagctcaa atctttcaga atagaacaat actaactatc
     1081 gaacaccccg tcttcataaa tacatatgta attctaggcc tagaattcct ataaactaaa
     1141 tgctttcata ctcttccaag taattgattg ccttaaattt taatttttga aggtttctaa
     1201 agctagaata gccccatcac aatcagtttt gattgattca caatttagaa acactatagt
     1261 ttcactcctg ttaaaataaa aaggaactgc ataaagcaat ccctttctga ttttgaaatc
     1321 atttacttaa cattttatag cagaacctag gtcaaaaaag gcaagtaaag tatctgctgg
     1381 attttcggaa acaaccctat ctacttgatc aaaactcgtt ccaattcctc cgccctcggt
     1441 tcctcctaca taagtaatcg gaacatcttt agctacttta ctaatcagtt caacaacacc
     1501 ttctgcaatg tgtttggaat gtgaaacgat aacaagacca ataccaatac tttccatcaa
     1561 accaccccag tttctaaaat agcagtaaag agtaatcctg atgagaatga tccaggatca
     1621 atatgtccaa gaaaccacat gctcctaaga caagagctaa cagactggcc atcaataata
     1681 gtattgttct ttttttcatc attactcctt aactagtgtt taactgatta attagccagt
     1741 aaatagttta tctttattta cactatctgt taagatatag taaaatgaaa taagaacagg
     1801 acagtcaaat cgatttctaa caatgtttta gaagtagagg tatactattc tagtttcaat
     1861 ctactatatt ttgcacattt tcatgaaaaa aatgagaact agaactcaca ttctgctctc
     1921 atttttcgtt ttcccgttct cctatcctgt ttttaggagt tagaaaatgc tgctaccttt
     1981 acttactctc ctttaataaa gccaatagtt tttcagcttc tgccataata gtattgttgt
     2041 cctgggtgcc aaatagtaaa ttatttttta atcctgtgag agtctctttg gcattggact
     2101 tgataattgg atcctggatt tttccaagta aatcttcagc ctctctcagt ttttctttaa
     2161 ccttttcagt ctcgacctga ggttcttctg attcctctgg tgattcttct tctggttcct
     2221 ctgttggttt tggagactct ggtttctcgc tttgcggttt ctcttctcga ggggtttctt
     2281 cctcaggttt ttctgtctga ggtttctcct cgtttggttt ttccgtttga ttggtatcag
     2341 cttgaccatt tttgtttctt
//
LOCUS       DAVMAH010000107         2242 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVMAH010000107 DAVMAH010000000
VERSION     DAVMAH010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2242
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.108"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..415
                     /locus_tag="VYO94_002026"
     CDS             <1..415
                     /locus_tag="VYO94_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760590.1"
                     /translation="YTHRVLGIVNFFKYYESSKFHLFFGDAELAFGDMTKGYTHNIRS
                     VLGWDGTVEMPLLSVMIKNGYVGLIGYGVVLFKFISSVLSMEDRRVKNIGLSILIPLL
                     LSAMVENYIVNISFVFMPVCFCILCSIKNIEFKNN"
     gene            425..1393
                     /locus_tag="VYO94_002027"
     CDS             425..1393
                     /locus_tag="VYO94_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1760591.1"
                     /translation="MKKVSIILPVYNVEQYIKKCLESIQQQTYPNLEVIIVNDGATDK
                     SVEYCEQICKIDSRFSVTHKENGGLSDARNVGIDKAKGDYLIFVDSDDFVSQDMVSYL
                     VSSMENNEADIAICDPAHYYSDRQNNDLNIFYPASSVKVYEKTEALCEMFYQKSFLVS
                     AWAKIYKKELFDDIRFPVGKLFEDSAVMYLLFEKCEKIVYSNAKLYAYVHRDNSITTK
                     KFSDKDLDILDISNTILDHYSGNFRVYKAAVSYKVSACFRILLNSSSEKKYNQIQKDC
                     MTYILRNWRNVLFDKNVRLKNKLALISITLFNPFVKFIYSKVNRWE"
     gene            1400..>2242
                     /locus_tag="VYO94_002028"
     CDS             1400..>2242
                     /locus_tag="VYO94_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001045980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 61 protein"
                     /protein_id="HEV1760592.1"
                     /translation="MNKYEERYQEDLSKNDFEKLINRRYLSDKELQVEYVKKGTVLPP
                     KVFEMKLSNKLGLQKALHGKGGVVDSKGNYVELSEQKAVGMRNRVYGSYKFNHKNLAI
                     RNEKVIYLNYFINQWGHFLLDVVGRLWYPLLKDTDTKLDYTCYAGTETKLEGNYLEFL
                     ELLGIDKSRLILINRPTQFSEIIIPESSILPGEYYTKEYKMLFNSLVANVKLDNNLES
                     KKIYCSRARLDLAKGKEFGENGIEKVFLKNGYTPVYMETMSLKEQIRTLLSATTIVLT
                     SGSLA"
BASE COUNT          807 a          281 c          406 g          748 t
ORIGIN      
        1 ctatactcat cgtgttttgg gtattgttaa tttttttaaa tactacgaat ctagcaaatt
       61 tcatttattt tttggtgatg ctgagttagc ctttggtgat atgacgaaag gttatactca
      121 caatataaga agtgttttag gttgggatgg aactgtggaa atgccgttgc taagtgttat
      181 gataaaaaat ggttatgtcg gcttaatagg gtatggagta gtcttattta aatttatatc
      241 ctctgtatta tctatggaag atagaagagt aaaaaatatt ggcttatcca ttctaatacc
      301 tctacttcta tcagcaatgg ttgaaaatta tatcgttaat attagctttg tattcatgcc
      361 ggtctgtttt tgtattttat gctcaataaa aaatatagaa tttaaaaata attgaaagtg
      421 atttatgaaa aaagtaagta ttattctacc tgtctacaat gttgaacagt atataaaaaa
      481 atgcttagaa tcaattcaac aacaaactta tccaaatttg gaagtaatca ttgttaatga
      541 cggagcaacc gataaaagcg ttgaatactg tgagcaaatt tgtaagatag attctaggtt
      601 ttctgtcact cacaaagaaa atggtggact ttccgatgca agaaatgtcg gtatagataa
      661 agccaaggga gattacctca tttttgttga cagtgatgat tttgtctctc aagatatggt
      721 atcttattta gtatctagta tggagaacaa tgaggcagac attgctattt gcgatcctgc
      781 tcattattat agtgaccgtc aaaacaatga tcttaatatt ttttatccgg catcaagcgt
      841 taaggtttac gaaaaaacgg aagctctatg tgagatgttt tatcaaaaat cttttttggt
      901 atctgcttgg gctaagatat ataaaaagga actatttgat gatatcagat tccctgttgg
      961 gaagttattt gaagatagtg ctgttatgta tctgcttttt gaaaaatgtg aaaagatagt
     1021 atattctaat gcgaaattat atgcctatgt gcatagagac aatagtatta caacaaagaa
     1081 gttttcagat aaagatttag atattttaga catttcaaat actattcttg atcactatag
     1141 tgggaacttt agagtttata aagcggcagt ttcctataaa gtttcggcat gttttagaat
     1201 tttgttgaac tcatcttcag aaaaaaaata taatcaaata caaaaagatt gtatgacata
     1261 tattttacga aattggagaa atgtgttatt tgataaaaat gtccgattaa agaacaagct
     1321 tgccttgatt tctataactc ttttcaatcc ttttgttaaa tttatctata gcaaagtaaa
     1381 cagatgggaa taatagcaaa tgaacaaata tgaagaaaga tatcaggaag atttatctaa
     1441 gaatgatttt gagaaactaa tcaatagaag atacctatcg gataaagaac tacaagttga
     1501 atatgtaaaa aaaggaacag tgttacctcc caaggtcttt gaaatgaaac tatcaaataa
     1561 acttggtcta caaaaagctt tgcatgggaa aggtggtgtt gtagattcaa aggggaatta
     1621 tgttgaactt tctgaacaaa aagcagttgg gatgagaaat cgagtctatg gatcttacaa
     1681 atttaaccat aaaaatttgg ctatcagaaa tgaaaaagtt atttacctaa actatttcat
     1741 aaatcagtgg ggacattttt tactagatgt tgtggggaga ttatggtatc cattactaaa
     1801 agatactgat actaaactgg attacacatg ttatgctggt acagaaacga aacttgaagg
     1861 aaactattta gagtttttag aactcctcgg tatagataaa tcacgcttaa ttttgataaa
     1921 tcgcccaact caattctcag agataattat acctgaaagt tcaattctgc caggtgaata
     1981 ttatacaaaa gaatataaaa tgctttttaa ttctttagta gcaaatgtta aattagataa
     2041 caatttagaa tcaaaaaaaa tttattgttc acgagctagg ctagatttag caaaaggtaa
     2101 agagttcggt gagaatggta ttgaaaaggt cttcttaaaa aacggttata ctccagttta
     2161 tatggaaaca atgtctttga aagaacaaat aagaacgcta ttatcagcta caacaatagt
     2221 attaactagc ggttcgttgg ct
//
LOCUS       DAVMAH010000108         2194 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVMAH010000108 DAVMAH010000000
VERSION     DAVMAH010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2194
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.109"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(236..640)
                     /locus_tag="VYO94_002029"
     CDS             complement(236..640)
                     /locus_tag="VYO94_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1760593.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQLIAYIGAVLCLIIMLLLMWGLKYYKK"
     gene            complement(637..801)
                     /locus_tag="VYO94_002030"
     CDS             complement(637..801)
                     /locus_tag="VYO94_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760594.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            complement(1098..1217)
                     /locus_tag="VYO94_002031"
     CDS             complement(1098..1217)
                     /locus_tag="VYO94_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1760595.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(1321..1470)
                     /gene="blpO"
                     /locus_tag="VYO94_002032"
     CDS             complement(1321..1470)
                     /gene="blpO"
                     /locus_tag="VYO94_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV1760596.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCTAGVAYGAIDG
                     CATTV"
     gene            complement(1714..1917)
                     /gene="blpN"
                     /locus_tag="VYO94_002033"
     CDS             complement(1714..1917)
                     /gene="blpN"
                     /locus_tag="VYO94_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV1760597.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(1933..2187)
                     /gene="blpM"
                     /locus_tag="VYO94_002034"
     CDS             complement(1933..2187)
                     /gene="blpM"
                     /locus_tag="VYO94_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV1760598.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
BASE COUNT          778 a          460 c          292 g          664 t
ORIGIN      
        1 cgtgcatcag ttagttgttt acttgcttca taattcatag aactatagta aaatgaaata
       61 agaacaggat aaatcgatca ggacagtcaa atcgatttct aacaatgttt tagaagtaga
      121 ggcgtactat tctagtttca atatactata ccatattttg tttcgcaggg aatctattat
      181 aaaagagtaa gtattgcaaa aacacttacc cttttctttt atacttcatt aagctctact
      241 ttttataata cttcaagccc cacatgagca gaagcatgat gattaagcag agaacagcgc
      301 caatataagc gattagttgt tgataagatt ctcctgctgt gatacctcta tacaaacaaa
      361 taatagacat aaaacctgtc aagccgataa acataagttg attggttcta ggactaacca
      421 aatcatcatc ttcaaactct cttatcctca tttccctagt gagataaaca gtaaccaaaa
      481 tagaagccaa gttaataact actaaaagaa attggaaaac tacggaaaaa tttaaaaact
      541 gacgagatag aaatagataa gtagaaacaa gcaagggcaa ctgacctaag aacaatctcg
      601 caaggaagat gttccgtttt ttagcaagaa aagttttcat ttcttttctc ctttcttttt
      661 attgatagca aaatagatca taactgcaat cacataggct atggtataaa atagctgata
      721 ccaagcactc tccctaagcg gatatagaaa gatggacatg attagataca gaacgaaaat
      781 aatcagtatt tttttcttca taagatttcc tcctaaatgt gcgatttatc ttagttgagc
      841 aagaacattt acactgctag tatagcactt attttgacct tggatcactc aaatcataaa
      901 tggtcatcaa aacctcttga attgtaaaaa ttaaaaaagc aagcatgaaa aacatacttt
      961 cctctttata ttgtattgat accaacttgt ttgtagactt ttcatcctgc tatcacatat
     1021 cattttgaca ggcgaaacaa tattaaagaa actcccctgt aaattaagct agcaaataca
     1081 ggggagaaat ttatttttta gagagtacta tccgtatcct ttttggaaga ttttgaaaat
     1141 atttttctaa ttaagtcatc catataagga ccaaatatac caactactaa accaataata
     1201 aaacttttaa aatccataat taccaccaac atattgctgc ataggctaca cctccaagta
     1261 tagctccacc tgcagcacca gttacaccta ttcctatagc aaatggtccc aatagaaatg
     1321 tcaaaccgtt gttgcacacc catcaattgc gccatatgca acccctgctg tacaactaat
     1381 ttttcttccc caatcaatat ctccaccttc aacgcaagca agcatttcat tatccataac
     1441 tgcaaattgt gacatcattt ttgtatccat atagtatatc acttttcagt tacggaacaa
     1501 gtttaatata aaaattatca aaaaaacata ggcaataaag agaaaaatta atttatcata
     1561 gattagaaat aatatgacaa aacaattcaa tgatgttaat tcaatagtct tttgtttttt
     1621 atcggagata cttatggata gataaataag ataggtttga aaagcgaaga gaataataaa
     1681 gaatatagcc ttcataaaat ttagctttca tttttatgat gtagcggtat aggctaaata
     1741 tccacaaacc actgctcctc caattcctcc tattgcagcg ccccatggtc ctagaagtct
     1801 cccatatttc actccacccg ctgcacaacc taaagcagca actacagctg ctcctccgga
     1861 attacctcca taaacctcac tcagcattgt ttcatttata ttacaataag tattcataca
     1921 agtctccttt tattaaaatc cacccgttgc ccctgttact cctgcccaaa gatccacacc
     1981 aaatttagct cctatgtatc cacatgctcc cataaatggt gctccaacac cactcgcagc
     2041 acaaatagct gtccctagcc cccagccacc aaaagcagca ccaccacctt ctaagacatt
     2101 agtttgccaa ttattcttgc ctccttcaat actagataac atagttatat ccatttcatg
     2161 aaattgttcc ataatttttg tatccatgac aaat
//
LOCUS       DAVMAH010000109         1977 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVMAH010000109 DAVMAH010000000
VERSION     DAVMAH010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1977
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.110"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(<1..506)
                     /locus_tag="VYO94_002035"
     CDS             complement(<1..506)
                     /locus_tag="VYO94_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1760599.1"
                     /translation="MKDLVSVVIPVYNVENYLEECIQSVLNQTYTNLDIVLVNDGSTD
                     ASAEICDRFAEIDGRVRVFHTENRGAALSKNFGVTQALGEYVLFVDSDDIAEKRMVET
                     LYRQVEETGADIVIGNYFLYDENDGQCKFYVLERDFCIEELSAQELIDRQAGKWHLNA
                     SAFIMPMF"
     gene            complement(1221..>1977)
                     /locus_tag="VYO94_002036"
     CDS             complement(1221..>1977)
                     /locus_tag="VYO94_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1760600.1"
                     /translation="SASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSAST
                     SASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSA
                     STSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSAST
                     SASISASTSASTVTSASDTMSTSTSVSTSESTSTSGSTNSRPQEQETTTKSRQELPNT
                     GEKQSVKSGLLGLILGLTGLGLVAKRRKRDDED"
BASE COUNT          559 a          418 c          328 g          672 t
ORIGIN      
        1 ttaaacatag gcataataaa agctgaagca tttaaatgcc actttccagc ttgacgatca
       61 atcaattctt gagcggataa ttcctcaata caaaaatctc tttccaaaac ataaaactta
      121 cactgaccat cattttcatc ataaagaaaa taatttccaa ttacgatgtc cgctccagtc
      181 tcttctactt gtctataaag cgtttctacc attctttttt cagcaatatc gtctgaatct
      241 acaaagagta catactcccc cagtgcttga gtaacaccga agtttttgga tagagctgca
      301 cctctattct ctgtatgaaa cacacgaaca cgaccatcta tttcagcaaa tctatcacat
      361 atttctgctg aagcatctgt agaaccgtcg tttaccaaaa ctatatccag atttgtatag
      421 gtctgattca gaacactttg aatgcactct tccaaataat tttccacatt atacacaggt
      481 ataacaacac taactaaatc tttcaattct actccttttc atacttactc tcattccctc
      541 aacttcgttt aactaccgca agtgaagaaa cacaatatcc aatcacgatt tgagaaatcc
      601 atgaatttct aggatatgtt ttgataccgc cacattctct ctttatacct caactaaaac
      661 aactcgataa actaactcac tctcacaaaa atagcattca aaacaattat accaagtaaa
      721 aaaacgaata ttaaaaatta gctccattag aactcatttt atgactacct agttctgagt
      781 aagtattatc ttaaaactga actactagaa ctttttctct cattttgtaa aacagaaaat
      841 agttcaaatt attttaatga aaaggtattc actaaaaaat catacttaat taaaatcaaa
      901 gtgtactttt taatcgacag ttgcttcaga aatagcctag tccaagtata tactttaaca
      961 tccaacagtt cttataggta tgattatatt ctggagagtc aacaaaaggc tcctaatcaa
     1021 gactataatt tatgtgtcta caaggcgcaa atttataatc tttttgattt ttaatgagta
     1081 gcaatataaa acttcctact ataaactata ccattttttg tctaatcata aagaagtatc
     1141 tacgctatat tttccatcaa aaaaactcca aaagtttttc tatttagtct agcaatctct
     1201 ttcaactgcg aaagtcaata ttagtcttca tcatctcttt tacgacgttt ggcaaccaat
     1261 cctaaacctg ttaaaccaag tatcaatcca agaagtcctg atttcacaga ctgtttctct
     1321 cctgtatttg gtaattcctg tcttgatttt gttgttgtct cttgttcttg tggtcgagaa
     1381 ttagttgatc cacttgtact tgttgactca gaggtactta ctgacgtact tgtactcatt
     1441 gtgtctgagg cacttgtaac tgttgaagct gatgtgctgg cacttattga tgctgatgta
     1501 cttgcacttg ttgatgccga tgtacttgct gacgtacttg ccgatgtgct tgcacttgtc
     1561 gatgctgacg tgcttgccga tgtacttgct gatgtacttg ctgatgtact tgcgctcgtt
     1621 gaggctgatg tgctagctga cgtgctggcg cttgttgatg ctgacgtact tgctgatgta
     1681 cttgcacttg ttgatgctga tgtacttgct gacgtacttg cacttgttga tgctgacgtg
     1741 cttgccgatg tacttgcgct tgttgatgcc gacgtgcttg ctgatgtgct tgctgacgta
     1801 cttgcacttg ttgatgccga cgtacttgct gacgtacttg ccgacgtact tgcacttgtt
     1861 gatgctgatg tacttgccga cgtgcttgcg cttgttgatg ctgaagtgct tgcgcttgtt
     1921 gatgcggacg tgcttgctga cgtgcttgct gaggtcgacg cgcttgttga tgccgac
//
LOCUS       DAVMAH010000110         1854 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVMAH010000110 DAVMAH010000000
VERSION     DAVMAH010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1854
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.111"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            70..207
                     /locus_tag="VYO94_002037"
     CDS             70..207
                     /locus_tag="VYO94_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV1760601.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDEMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            502..1853
                     /locus_tag="VYO94_002038"
     CDS             join(502..943,943..1853)
                     /locus_tag="VYO94_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1760602.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLQQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNSMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
BASE COUNT          645 a          285 c          414 g          510 t
ORIGIN      
        1 tggtggagag aatataatga gggtggataa agtacttaat cccaaaaatt taaataggag
       61 gagctagcta tggcagaaga agtattaaat cttcaattag tatctgttca agttgacgaa
      121 acagatgaag ttgatgaaat gcgatttagt acattcagta caaaccgttg cggtaactgg
      181 agtgctttta gttgggaaaa ttgttaattc atttaaattg taaactttag ggattctctg
      241 gagttatgga tgtcgttcca atatgtgtac gttggaatgt tagtgcttat atgggggaac
      301 agaatcctct cttgattgaa gacaagttag ccattaggct ggtttgtctc tttgtcaact
      361 gtagtgggtt gatataatag tattagtgag tgggataaaa gtttcattta gtttattcag
      421 tacaaattta acgggtcaag attttatgaa ctgcacccca aaagttagac agaaaaaatc
      481 taacttttgg ggtgttttat tatgaaattg agttatgaag ataaagttca gatctatgaa
      541 ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa gatttggtgt ggatgtttct
      601 ggtctaaagt acatggtgaa attaattgac cgttatggca tagaaatcgt taaaaaaggg
      661 aagaatcgtc actattcttc taaattgaaa caagaaatga tggataaagc cttactggaa
      721 ggttgttcac aaagaagtat tagtcttgat tatgccctcc caaaccaagg aatgctttca
      781 ttttggccgg cacaatacaa gaaaaacggg tatactattg ttgagaaaac aagagggaga
      841 ccagctaaaa tgggacgtaa acggaagaag acttgggaag aaatgacaga actagaacga
      901 ctccaggagg agaatgaacg cttacggact gaggtggcct acctaaaaaa gttaaaagag
      961 ttagaggaaa gggacgaagc cctagagcga gaaaggcaga gacagttaga gaaatggttt
     1021 caggaggatt tcgactagat tttcttcttg aaacagcacg tttagctcgc tcgacttact
     1081 attatcagtt gcaacaactg gatggggttg ataaagataa agagattaaa accgaaattc
     1141 agggcattga taatgaacat aaaggcaact atggctatcg tcgaatccat ttagaactaa
     1201 ggaatcgtgg ttttgtggtc aatcataaga aagttcaacg gttgatgaga attcttggtt
     1261 taacggctcg aattcgccgt aaacggaagt attcttccta ccaaggagag attggcaaga
     1321 aagcagagaa tctcattcaa cgccagttcg aagcatcgag gccaatggaa aagtgctata
     1381 cagatgtgac agagtttgcc attccaaata gcacacagaa actctattta tcaccagttt
     1441 tagatggttt taacagtgaa atcattgctt atcatctttc tacttcgcca aacttagaac
     1501 aagtgaagag tatgttagaa caggccttta cagagaaata ctatgagaat acgattctcc
     1561 atagtgacca aggctggcaa taccaacacg attcttatca tcggttccta gagagtaagg
     1621 gaattcaagc atccatgtca cgcaagggca acagcccaga caacagcatg atggaatctt
     1681 tctttggcat tttaaaatcc gaaatgtttt atggctatga gaagaacttt agatctttag
     1741 aaaaccttga acaagctatt gtggactaca ttgattacta caacaacaaa cgaattaagg
     1801 taaaactaaa aggacttagt tctgtgcagt acagaactaa atcctttgga taaa
//
LOCUS       DAVMAH010000111         1853 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVMAH010000111 DAVMAH010000000
VERSION     DAVMAH010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.112"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(269..553)
                     /locus_tag="VYO94_002039"
     CDS             complement(269..553)
                     /locus_tag="VYO94_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760603.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(1167..1337)
                     /locus_tag="VYO94_002040"
     CDS             complement(1167..1337)
                     /locus_tag="VYO94_002040"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1760604.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
BASE COUNT          557 a          276 c          315 g          705 t
ORIGIN      
        1 tgataaaatg taattgttcc atatgaatct ttctaatgag ttgttttgtc gcttttcatt
       61 ataggtcata tgggactttt tttctacaca aaaataggct ccataatatc cataggggat
      121 ttacccacta caaatattat agagccataa aagcatcaac atcttgtgtg gcacgtaaac
      181 catgatattc taagacataa ccataattgt taaagtcaga ttttcctgaa ttaatttctt
      241 atttagggct tggaagaccg gtttcatttt atccatgttt gtatttctcc atcaattttt
      301 gaacattggt taacttagca ggtttattta atgaaatcac atatttatga gttggagtat
      361 gctcttgaaa ggcatacttc aagctaattt tttgaaaacg ggttagttct ttggagtcta
      421 gcaacttttc tacatcttgg tttgttaaat aagaatagtc ttcaaaaata acttttcgca
      481 aatagcgaaa ccaatggctt gcgttgaatt gtgattgttt ggatgcctgt atcatataat
      541 cgtaccaatc cattgtcttc ctcctataaa atttagttta tattattgta gtttatattc
      601 aaaaatgtag tttttcttaa ttagctcgta tctataggat gatactgaaa atcttcttgt
      661 tgctttaaat cacaatcgaa aaattctgtt tttcatctta gaaaagaatg tttagaaatg
      721 taaaatgaac cttttttctt atccgaaaac cttactaaag tatataattt aggcagtcaa
      781 ttctgtatga taatgtttgt actatcgtcg agtttttgct tgattgccta acgagataaa
      841 ttttagaaga gttttcggtg tgatttgaca agtttctgac tggaaggata gttacactag
      901 tattgtttat taaaatgagc agatagagaa aatttggaat ctatttgctt attatcaatc
      961 gtttttttag cttatttgtc ttagattggt atagaactga gctatggatt aatcttcttc
     1021 tatcttatcc tgttcctaaa tatgttggta gaaaaatgaa gcagttgtta ggagtgtctg
     1081 tattggaaaa aaaattttgt ctatacaatt ctttaaatga tatgaagact aggaatgcca
     1141 aaacactgac atatttcgtt taaagcctat ccagtctctt caattgtatt tgtagaaatg
     1201 ctatcagtaa tatattcgcg aacactatga tttacaacag tgtggtcgta catctttgta
     1261 actttattat acaacaacca tttacaggtg taaagttgag cagtgtcttt agtaaattta
     1321 gggacttgtt ttgtcacagt tttgatacct gtattcgttg tttcatgagc atttaacgtt
     1381 tcttttcatg taggcatttc aataattaga atgatatttt tccgaggatg aacttatata
     1441 ttgtgacttt ttagagttat gatgcctctt gatttgacta tcgctatcaa tttcatccac
     1501 ttttacagtt tcatggtttt atgaaccgaa acatctaggt acaggtttta gcatcaattg
     1561 attgtttttg agctatatga agttgaaacg tggagatgct tttcttgtga taacgcccta
     1621 ttcaaagagg cataaccgtt tttggagaga gttcagtact atgtggcgct aaataatata
     1681 tgtaaaatag tatggtgtag agatattaaa caagatttaa ctaatacttt tcgaaaatct
     1741 cttcaaacca cgtcagcgtc gccttaccgt atagatgtta ctgacttcgt cagttctatc
     1801 tacaacctca aaacagtgtt ttgagcagcc tgcagctagc ttcctagttt gct
//
LOCUS       DAVMAH010000112         1798 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVMAH010000112 DAVMAH010000000
VERSION     DAVMAH010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1798
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.113"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            372..848
                     /locus_tag="VYO94_002041"
     CDS             372..848
                     /locus_tag="VYO94_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1760605.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            848..1609
                     /locus_tag="VYO94_002042"
     CDS             848..1609
                     /locus_tag="VYO94_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEV1760606.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
BASE COUNT          661 a          239 c          349 g          549 t
ORIGIN      
        1 aaatatcagt aaaaacaaca ctttattgag gtattggata cgctttgcta atagcctaat
       61 aatcacatgt ggagtgttgc tacaacgaaa aaggtgataa tccttgattt caagctattt
      121 tataagcatt ttgtctttgt agataaaggc aattttgaca ataaaaatcc taaaaggtga
      181 atcgttatag atgtatttgt agatatcgtt tgcgcatcga aaaaattaat acaagaataa
      241 atatttatgg ctctttaggt gacttttata gaagtaaagt ttaggataga aaaacaagaa
      301 ataacgcacc atttttggtg cgttatgctt ttttatgcta taatggattt ataaaaataa
      361 aggagtttgc tatgattgga aagaacataa aatccttacg taaaacacat gacttaacac
      421 aacctgaatt tgcacgaatt ataggaattt ctcgaaatag cttgagtcgt tatgaaaatg
      481 gaactagttc agtctctacg gaattaattg acatcatttg tcagaagttt aatgtatctt
      541 atgtcgatat tgtaggagaa gataaaatgc tcaatcctgt tgaagattat gaattgactt
      601 tgaaaattga aattgtgaaa gaaagaggtg ctaatctatt atctcgactc tatcgttatc
      661 aagatagtca gggaattagc attgatgatg aatctaatcc ttggatttta atgagtgatg
      721 atctatctga cttgattcag acaaatatct atttagtaga aaattttgat gaaatagaga
      781 gatatagcgg ctatttggat ggaattgaac gtatgttaga gatatctgaa aagcggatgg
      841 tagcttaatg gaaatccaag attatactga tagtgaattc aaacatgctt tagcaaggaa
      901 tcttcgttca ctgacaagag gaaaaaagtc cagtaaacaa cctatagcga ttttgcttgg
      961 aggtcaaagt ggtgccggta agactacaat tcatcgtatt aaacagaaag aatttcaagg
     1021 aaatattgtt atcatagatg gtgatagttt tcgttctcag catccacact atttagaact
     1081 gcagcaagaa tatggcaaag acagtgtaga atataccaaa gattttgcag gaaaaatggt
     1141 agagtcttta gtaaccgaat tgagtcattt gagatacaat cttttgatag agggaacttt
     1201 acgaacagtt gatgttccaa agaaaacagc acaactcttg aaaaataagg gatatgaagt
     1261 acaattggcc ttaattgcga caaagcctga attgtcgtat ctaagtactc ttatccgtta
     1321 tgaagaactg tacattatca atccaaatca agcacgcgca actccaaaag aacatcatga
     1381 tttcattgta aatcatctag ttgataatac acgacaattg gaagaactgg ctatctttga
     1441 aagaattcaa atttaccaac gagatagaag ttgtgtatat gattcaaaag aaaatacaac
     1501 ttcagcagca gatgttcttc aagagttact gtttggggag tggagtcagg tagagaagga
     1561 gatgttgcag gtgggggaaa agagacttaa tgaattactt gaaaaataaa caattgatat
     1621 ttttaggaga gtagaaatga gagggtttaa taacaagata aagtctgttt atcaagaact
     1681 aacaaattcc aaagagaaat tcggtagctt tcacaagact ttaattcatt tgcatacacc
     1741 tgtttcttat gattacaagc tattttctaa ttggactgca acgaaatata gaaaaatt
//
LOCUS       DAVMAH010000113         1771 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVMAH010000113 DAVMAH010000000
VERSION     DAVMAH010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1771
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.114"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            1..822
                     /locus_tag="VYO94_002043"
                     /pseudo
     CDS             1..822
                     /locus_tag="VYO94_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            815..1690
                     /locus_tag="VYO94_002044"
     CDS             815..1690
                     /locus_tag="VYO94_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1760607.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLF"
BASE COUNT          670 a          164 c          345 g          592 t
ORIGIN      
        1 attttttata tatgttaaaa aacttgacaa gaatggattt ggaaaggtta agacagtgat
       61 aacatgccat ggatgggttg aatataactt aaaaaagaaa ttcttgactt attttgattt
      121 ttggacatat tctatgggag atgcttttat ttgtgtatct gaaactatga aaaaaagatt
      181 ggagagtata ataaaaaaat aagaagatag ttgcaataaa taacggaatt aatgtatcaa
      241 atagcgattt agatgtagta ggtgttcaag actttaaaaa agaattttgt attccaaata
      301 acaaaaaaat catttgttat gttggaaggt tggatccaga aaaaaggccg gatagattcc
      361 ttgaatttgc agaaaaatta tttttagtca gagaagatgt gatttttatt atgactggaa
      421 atggtagtat gtgggctgct ttgaaagaaa aaatttgcca tttgaaatgt agagataatt
      481 tcaggttact tggtgaaatc tatccagcta ctatagttta ccaaatatcg gatttattgt
      541 atattccttc tgatacagaa ggaataccta tgtgtgtttt agagtcaatg tcacaaggaa
      601 ctccggtttt agctagtaat gttggcgggt taagtgaaat tattgaacat agggttgatg
      661 gatttttatt tgagaaggaa gatgttgagg gagtgtgtgc ttgtgctaat tttttactca
      721 atgattctga gtatttgaaa tatataggtg agaatagtaa atcaaaaata agaaaacatg
      781 agagtatatg atgaattatt agagaagagt agtcatggat aggaatatag atcaagaatt
      841 agtaagtatt ataataccaa cacataatag gtatgaatct ctgattagag ctgtgaaaag
      901 ttgtttacat caaagttata aaaatatcga agttataatt attgatgata attatagtaa
      961 tgtaaattta agaaataaaa ttatccatca atttggctat accaatcata gaattaagtt
     1021 aattttaagt aatgaagatt taggtgcaac taatgccaga aacataggta tcaaaaattc
     1081 tagaggtaag tatatatcat ttttagacga tgatgatgaa tatatgccag atcgaatttt
     1141 aaagttgatg gcttgtttta aaaagagtag aatgaagaat ttagctttag tttatagtta
     1201 tggcataata atttatccaa atggtacacg agaagaggag aagaccgatt ttgttggaaa
     1261 tcccttgttt gttcaaatgg ttcacaatat agcaggtacg tcattttggt tgtgtaaaaa
     1321 agaggtgcta gaattaatta atggttttga gaaaatagat tcacatcagg acggtgttgt
     1381 tttattaaaa ctacttgctc aaggatacca aattgatata gtgcgagaat tcttggtgaa
     1441 ttactacgct cacagtaaag aaaacggtat cactggagtg acacaaaaaa caattaatgc
     1501 agatgaagaa tattataatt actgtaggaa atattttaat ttattgagtt tcaacgagag
     1561 aatattggtt acaaagaaat attattcttt aaacataaag cggttactat taataggaga
     1621 caaatgcaag gctttaaaag taatcaagaa ggcaagagaa gaaaaaattt ttaacgaatt
     1681 tcttttttga aatatatgtt attatatcat tttggctttt tctattgtat atatgacaac
     1741 tatgttcaat taaaatttag aaagtgagaa a
//
LOCUS       DAVMAH010000114         1747 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVMAH010000114 DAVMAH010000000
VERSION     DAVMAH010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.115"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            1..261
                     /locus_tag="VYO94_002045"
                     /pseudo
     CDS             1..261
                     /locus_tag="VYO94_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            276..1016
                     /locus_tag="VYO94_002046"
     CDS             276..1016
                     /locus_tag="VYO94_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1760608.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            1019..>1747
                     /locus_tag="VYO94_002047"
     CDS             1019..>1747
                     /locus_tag="VYO94_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1760609.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQMSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPF"
BASE COUNT          582 a          220 c          334 g          611 t
ORIGIN      
        1 aatgtggtga aaatggtagt aatttgtctg gaggtcaaaa acaaaaaata gctttagcta
       61 gagctctgat tagaaataat aaagtgtact tatttgacga aatatcagct aatttagata
      121 atgataattc aaattccata catgatattc tgttcaattt aggtatttca tttattgaag
      181 tttcacatca ttatgactta aatgacaaga gatacactga tatataaatt ggaaaatgga
      241 acacttttca aaattaagtg attggaggca agaatatgga taaagattat atattaaaag
      301 tgaaagggct gtatcatcaa tttttactgg gaaacaataa aacgttgcaa gtgctgaaaa
      361 atgtttctct ttctgcttcg agaggagaat ttataagtat tctaggaatt agtggttctg
      421 gaaagtcaac tttattaaaa tgtatttcta gtttgcttga accaacaagt ggggaagtaa
      481 ttttaaatgg aatcaacccc tataaaatca gaaatgcaaa attatcaagt ataagacgta
      541 atgaagtatc ttttatattt caagcatata atttaatacc ttccctgccg gtaatagaaa
      601 atatagcact tcctttgcga ttatcacaaa aaaaattaac tattaaaaat gtagaaaact
      661 tactcaaaag aatgaagttt aatgctggct taaacgattt tgttggaact ctgtctggtg
      721 gagaacaaca gaaggttgct atagctagag cggttattgc tgatagtgat ataatatttg
      781 ctgatgagcc aactggggct ttagacagcg tttctcgtga agtaattttt gaattattga
      841 gagagttagt aggggcgggt aagtgtgtaa ttatggtaac gcacgatata gaattggcct
      901 cgaaaactga tcgtgcatta atattgaaag atggaaaaat tttcaaagaa cttcatagac
      961 ctagcgggga agagttgtat aaaatcttag aggtacaatc aactacggag gaatagagat
     1021 gctcagatta gtttactatc aatttttaca taataagaaa caatggttag gcgtttcacc
     1081 agtaattttt gtttcgagtt tagttatggg attggctgtt aatggggtaa ttaatgttga
     1141 gaataattcg caagtatttg tcggacttcc agatcctaaa ccaattttta tgtttccgat
     1201 agtattcgga ggagtaacat tattctttgt gctctctaac ataataaata tgttggttga
     1261 aatttttaga gatgattacg aacttctgga ggtgttggga gcaagtcgcc ttcaactatc
     1321 atttcttgtg gggggacaga tttttatcat ttcctcgatt attagtttta ttgcatatct
     1381 atgctctata tttgttacgt caaattatta ttatttttta caatactttt tcggggaaaa
     1441 tatattacct gatatccaat ttcaaatgag tgctgttgga tgtatcatta cagtagtgtt
     1501 gatttcattt ttagcctttc taagtggttg cttttatacg ttcaagaaga ttagaaatag
     1561 gaagagttct aaaataaggc atgttctttc aatagtaaaa agaatactgc tattggctgg
     1621 ttttagtgtt atctggttgc tttctttgca acaaattttc caagatagca caattttagc
     1681 gaaggcccag ataatattca atattgtaat cttagatatt gtgattattt atcaattatc
     1741 tcctttt
//
LOCUS       DAVMAH010000115         1665 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVMAH010000115 DAVMAH010000000
VERSION     DAVMAH010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1665
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.116"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            18..1019
                     /locus_tag="VYO94_002048"
     CDS             18..1019
                     /locus_tag="VYO94_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1760610.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT          556 a          226 c          336 g          547 t
ORIGIN      
        1 cgtaatggag gactgaaatg aaaaatataa atgggaaaaa ggtaactatt tatgatattg
       61 cacgtttatc aggtttttct ccaaaaacag tttcacgagt tattaatggt ggagtaaatg
      121 ttaaagaaga aacttatcaa gcgattcaaa aagttataga ggaattgtcg tatattccaa
      181 atgcgtatgc aaaaaattta actaaaaaag aagctataaa tatattgatt tctgtaaaaa
      241 aaatcgactc ttttccttta atttggtttc atacgctgtt agataaagtg ttacggacgt
      301 gtaaagaatt tggtgttaat gctatagttg agtactttgg agaggaggat acaattagta
      361 attcaattat atcaagcaca ggtagcctag tagatggtgt tattgttttt tatgaaagtg
      421 tagatgatat cagaattcag tatttaaaga agaaccatat gccttttctt gttttcggtg
      481 aatctcaaac gtctggagta gtctatgtat ctaataataa ttttcaagct acttatgata
      541 tgatgaaagc tgtaactgaa gaaaaattta aaaatatgtg gttgcttatg ggaggagaat
      601 cccatgttaa taaggatcgt gaaagaggtg tgcgttcttt tctgaatgat aaaaattact
      661 ttatggattt aaaagtcatt tatggcttat ctacaattga ttcagtttat tcttatgcaa
      721 tgcagcactt gactacccaa aattatccgg acattatttt tgtttcagga gatgaaaagg
      781 ttcagggctt gattcgtgcg tgctatgaga aaggaattct tattccagat gatatttcta
      841 tcattggatt tgataatatt cctatttctc agtattatac tccagctttg tctacaattg
      901 ctcccaatta tgttaaattg gctaaagaaa tgatagaagg tgttttagca attattaaag
      961 gggaaagtgt cacatctgtt gaagtttctc ctaaatttgt taggagacag agtttctagt
     1021 attgtttaat tcttgaaaat cctagtggaa aagatggagt gttctaaaat aagttctgtt
     1081 tagcctccat tcagtttcta ttgagttgga tccaatttct aacgagtggg acatgttcat
     1141 gttcgatcta aggaagacat ggtcacattc gaatgatatt ttcaaaaaaa tcgtaaaaaa
     1201 gtcttgacaa agaaaaaaca aagtattaaa ataagttcaa caaatcagaa aagtaactat
     1261 ttttgatctt cagggagcct gtggtgattg tgaataggtg gttggaagta gtgaaagtgg
     1321 gctgattttg aaaatgaatt tgaaacaatg aaaattcggt gcgcacacct tacagtgcag
     1381 cttgttgtta aacaaggcag agatgtaaag ggatagtccc tttataattg aggtggcacc
     1441 gcgttaccaa cgccctcaca cggaagtata ttctgtgtgt gggctttttt ctatccgtcg
     1501 tttggtttat cttttattag ggccttaagt cgctttgatg aacttgagtt ctatctacag
     1561 ctccttgcct actactaaaa gcaaacaaaa aggctggact aatacgaaaa aagctagtaa
     1621 tactcaatga aaatcaaaga gcaaactagg aaactagccg caggc
//
LOCUS       DAVMAH010000116         1584 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVMAH010000116 DAVMAH010000000
VERSION     DAVMAH010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1584
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.117"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..458
                     /locus_tag="VYO94_002049"
     CDS             <1..458
                     /locus_tag="VYO94_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEV1760611.1"
                     /translation="DLFSEEEKRIYFQTTCEVSSKDSAINKYKMEKIIKRSNKGNVYR
                     AIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDIKNEAHMLKKLADKSYTTNLTDEFYI
                     VDDYFLVQEQVDGLNFEEFIRETEHSLNIREKTLYNIVNIVSDIHKLGI"
     gene            complement(532..1584)
                     /locus_tag="VYO94_002050"
                     /pseudo
     CDS             complement(532..1584)
                     /locus_tag="VYO94_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          481 a          280 c          275 g          548 t
ORIGIN      
        1 tggatttatt ttcagaagaa gaaaaaagga tttattttca aaccacatgt gaagtttcaa
       61 gtaaggactc tgcaataaat aaatacaaaa tggaaaaaat tattaagaga tcaaataaag
      121 gaaatgttta tcgggcaatt agaaaatcgg acgggcaaaa agtaatcatc aagcagtcaa
      181 gaccttttgt gaattatgat gctgaaggag aatggacagc tcttgatgat ataaaaaatg
      241 aagctcacat gctaaaaaaa ttagccgata aaagttatac tactaattta actgatgaat
      301 tttatatcgt ggatgattat tttcttgttc aggaacaagt tgacgggtta aactttgaag
      361 aatttattcg agaaacagaa cactccttaa atattagaga aaaaacactg tataacattg
      421 tgaatatagt aagtgacatc cataaactgg gaatataaaa ttgtagatat agctcctaca
      481 aattttatat ataccaaaaa tgtactgcac cccaaaagtt agacaattaa tttatccgaa
      541 ggatttagtt ctgtactgca cagggctaag tccttttagt tttaccttaa ttcgtttatt
      601 gttgtagtaa tcaatatagt ctacaatagc ttgttccaat tgcttaagcg actgaaacga
      661 cttctcataa ccgtaaaaca tttccgattt cagaatccca aagaaggact ccatcatacc
      721 attgtctggg ctgttaccct tacgtgacat ggatgcttga attcccttac tctctagaaa
      781 ccgatgataa gaatcgtgtt gatattgcca gccttggtca ctatggagaa tcgtattctc
      841 atagtgcttc tctgtgaatg cctgttccaa cattgtttgt acttgttcta agttgggtga
      901 agttgaaaga ttataggcga taatttcgct attaaagcca tctaaaactg gtgataagta
      961 aagcttttga gtacttgctg gaatggcaaa ttctgtcaca tctgtgtagc acttttccat
     1021 tgttttagag ccttcaaatt ggccttgaat gagattctct gccttcttac caacgtctcc
     1081 tttatgagaa gaatattttc gtttctgtcg cattttagct tgtaaattga gtactttcat
     1141 caagccttga actcttttat gatttaccag ataaccacga tttcttagtt ctaaatgaac
     1201 ccggcgataa gtataatttc ccttgtgttc gataaaaatg gattgaattt cagctttaag
     1261 ctcttggtcc ttatctggtt tatctagctg tttcaagtga tagtagtagg tcgaacgagc
     1321 tagtttaatg gcttttagaa gaagagctaa cgaaaactca gtcattaatt cttgaacaat
     1381 ttctgtcttt cttctttctc tttttcctcc ttcaatcgga gttctcttaa cttttttagg
     1441 atggcattct ccgctctcag gtactcattt tctgcttgaa gatgttctaa ttctgtcctc
     1501 tcttcaggtc tcgtttttgg cttacgtccc attttaggta ctctccctct tgttttctca
     1561 acaatagtat acccgttttt cctg
//
LOCUS       DAVMAH010000117         1556 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVMAH010000117 DAVMAH010000000
VERSION     DAVMAH010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1556
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.118"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(127..214)
                     /locus_tag="VYO94_002051"
     tRNA            complement(127..214)
                     /locus_tag="VYO94_002051"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(178..180),aa:Ser,seq:gct)
     gene            complement(221..294)
                     /locus_tag="VYO94_002052"
     tRNA            complement(221..294)
                     /locus_tag="VYO94_002052"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(258..260),aa:Ile,seq:gat)
     gene            complement(330..400)
                     /locus_tag="VYO94_002053"
     tRNA            complement(330..400)
                     /locus_tag="VYO94_002053"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(366..368),aa:Gly,seq:tcc)
     gene            complement(420..492)
                     /locus_tag="VYO94_002054"
     tRNA            complement(420..492)
                     /locus_tag="VYO94_002054"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(457..459),aa:Phe,seq:gaa)
     gene            complement(496..569)
                     /locus_tag="VYO94_002055"
     tRNA            complement(496..569)
                     /locus_tag="VYO94_002055"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(533..535),aa:Met,seq:cat)
     gene            complement(583..672)
                     /locus_tag="VYO94_002056"
     tRNA            complement(583..672)
                     /locus_tag="VYO94_002056"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(634..636),aa:Ser,seq:tga)
     gene            complement(683..756)
                     /locus_tag="VYO94_002057"
     tRNA            complement(683..756)
                     /locus_tag="VYO94_002057"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(720..722),aa:Ile,seq:cat)
     gene            complement(770..843)
                     /locus_tag="VYO94_002058"
     tRNA            complement(770..843)
                     /locus_tag="VYO94_002058"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(807..809),aa:Met,seq:cat)
     gene            complement(849..922)
                     /locus_tag="VYO94_002059"
     tRNA            complement(849..922)
                     /locus_tag="VYO94_002059"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(886..888),aa:Pro,seq:tgg)
     gene            complement(938..1011)
                     /locus_tag="VYO94_002060"
     tRNA            complement(938..1011)
                     /locus_tag="VYO94_002060"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(975..977),aa:Arg,seq:acg)
     gene            complement(1021..1106)
                     /locus_tag="VYO94_002061"
     tRNA            complement(1021..1106)
                     /locus_tag="VYO94_002061"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1070..1072),aa:Leu,seq:taa)
     gene            complement(1114..1185)
                     /locus_tag="VYO94_002062"
     tRNA            complement(1114..1185)
                     /locus_tag="VYO94_002062"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1151..1153),aa:Gly,seq:gcc)
     gene            complement(1208..1280)
                     /locus_tag="VYO94_002063"
     tRNA            complement(1208..1280)
                     /locus_tag="VYO94_002063"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1245..1247),aa:Thr,seq:tgt)
     gene            complement(1299..1380)
                     /locus_tag="VYO94_002064"
     tRNA            complement(1299..1380)
                     /locus_tag="VYO94_002064"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1344..1346),aa:Leu,seq:tag)
     gene            complement(1386..1458)
                     /locus_tag="VYO94_002065"
     tRNA            complement(1386..1458)
                     /locus_tag="VYO94_002065"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1423..1425),aa:Lys,seq:ttt)
     gene            complement(1483..1555)
                     /locus_tag="VYO94_002066"
     tRNA            complement(1483..1555)
                     /locus_tag="VYO94_002066"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1520..1522),aa:Asp,seq:gtc)
BASE COUNT          434 a          436 c          337 g          349 t
ORIGIN      
        1 aaactttgaa aacttcaaaa aacggatttt tatcgctctg aacatcaaaa aagaaaggac
       61 gaaatttgtc ctttctcaag cttagctttt cttcaaccca ctacagttga caaagagcca
      121 ttaaaacgga gaataaggga ttcgaaccct tgcgccagtt acccgaccta acgatttagc
      181 aaaccgtcct cttcagcctc ttgagtaatt ctccaattaa tgggcacgag tggactcgaa
      241 ccaccgacct cacgcttatc aggcgtgcgc tctaaccacc tgagctacgc gcccaagtta
      301 aaaaacttgg taatttgaac aaagttcaaa gcgggtgacg agaatcgaac tcgcgacaac
      361 agcttggaag gctgtagttt taccactaaa ctacacccgc ataaatacta tcaataaaat
      421 ggcgcgagac ggaatcgaac cgccgacaca tggagcttca atccattgct ctaccaactg
      481 agctaccgag ccttattgcg ggagcaggat ttgaacctac gaccttcggg ttatgagccc
      541 gacgagctac cgagctgctc catcccgcgt taataatata aaaggaggat gtgggattcg
      601 aacccacgca cgcttttaca cgcctgacgg ttttcaagac cgttcccttc agccggactt
      661 gggtaatcct ccaatattca aatggacctt gtaggacttg aacctacgac cactcggtta
      721 tgagccgaga gctctaacca gctgagctaa aggtccgaca agatcattat agcggcgaag
      781 gggatcgaac ccccgacctc ccgggtatga accggacgct ctagccagct gagctacacc
      841 gccatgaatc gggaagacag gattcgaacc tgcgacacct tggtcccaaa ccaagtactc
      901 taccaagctg agctacttcc cgagttaaat agaaaaatgc accctagagg agtcgaacct
      961 ctaaccgcct gattcgtagt caggtactct atccagttga gctaagggtg ctccatatta
     1021 tgccgaggac cggaatcgaa ccggtacgat cgttaccaat cgcaggattt taagtcctgt
     1081 gcgtctgcca gttccgccac cccggcctct ctaagcgaac gacgggattc gaacccgcga
     1141 cccccacctt ggcaaggtgg tgttctacca ctgaactacg ttcgcactgt tttcttctat
     1201 ctaaaaatgc cggctacatg acttgaacac gcgaccctct gattacaaat cagatgctct
     1261 accaactgag ctaagccggc tcatttgtta tatcttaatg cgggttaagg gacttgaacc
     1321 cccacgccgt taagcgccag atcctaaatc tggtgcgtct gccaattccg ccaaacccgc
     1381 atatatgacc cgtactgggc tcgaaccagt gacccattga ttaaaagtca attgctctac
     1441 caactgagct aacgagtcta aaataacttg cgttacctta aacggtcccg acgggaatcg
     1501 aacccgcgat cttcgccgtg acagggcgac gtgataaccg ctacactacg ggacct
//
LOCUS       DAVMAH010000118         1548 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVMAH010000118 DAVMAH010000000
VERSION     DAVMAH010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1548
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.119"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            376..1071
                     /locus_tag="VYO94_002067"
     CDS             376..1071
                     /locus_tag="VYO94_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760612.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            1083..1499
                     /locus_tag="VYO94_002068"
     CDS             1083..1499
                     /locus_tag="VYO94_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760613.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPIYQRQGIGSALMKEALKDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
BASE COUNT          476 a          237 c          377 g          458 t
ORIGIN      
        1 tatttttatt cgcaggtaaa agttgtagat aaacttactg attctgaatc gaaaaaatac
       61 ggtgaatata ttgatttgta cgaatcgtgt cgtcagaaca atttaagtgt tctacttaac
      121 tttcttcaaa attcggatga taaacgagga gttattgcta gtaactcagt gagaattatg
      181 tttgaatctt tggataaagc agaccaaatt gcggccctga atatttgtag aaactatgta
      241 gcacgagaaa atgttttaaa taaagaagat gcagaaaatt gttaaatgaa attgataaaa
      301 aacttgaaat tagcagatag gacaattcaa atagagttga gtaaaaagtt tgaaaagtga
      361 aacaaggaga aagctatgcc agtaaatgaa tatggtcaga tgattggtga gtcaatggaa
      421 ggttatacac ccggtgcact gccttctatt gatttcttag aagggcgtta tgctaggata
      481 gaggctctct cggtagaaaa acatgcggag gatttgctag ctgtttatgg cccggatact
      541 cctcgggaga tgtggaccta tctttttcag gagccagtag cagatatggg ggagctggtt
      601 agccttttaa atcagatgtt ggctcgtaag gaccgttttt actatgcaat catagacaag
      661 gcgactggta aggctttggg aactttttct ctcatgcgca ttgaccagaa taaccgagta
      721 atagaagtcg gagcagtcac tttttctcca gagctaaggg gtacacggat aggaactgag
      781 gctcagtatc tcctagctcg ctatattttt gaggagctaa actatcgtcg ctacgagtgg
      841 aaatgcgatg ccttaaatct gccatccaga cgagttgcgg agcgtttggg atttgtctat
      901 gaaggaacct tccgccaggc ggtggtttat aaggggcgta cgagagatac ggattggttg
      961 tctatgattg atatggactg gcctcaagtc aaagatcgtt tggaaacatg gctgcgtcct
     1021 gaaaattttg ataaaaatgg acagcagtac aagagcttga gagaacttta agaggtgttg
     1081 agatgattac tattaaaaag caagaaattg tcaagctaga ggatgttttg catctctatc
     1141 aggctgtcgg ttggacaaat tatacccatc aaccagagat gctggagcat gccttatcgc
     1201 attcattagt aatttatctg gcacttgatg gtgatgctgt ggtgggcttg attcgtttgg
     1261 ttggagatgg attctcatca gtttttgtac aggatttgat tgttttacca atctatcagc
     1321 gtcaagggat tggtagtgcc ctaatgaaag aggccttaaa agattacaaa gatgcttatc
     1381 aagtccagct ggtgacagaa gagacagaaa aaaacgtggg attttatcgt tctatgggct
     1441 ttgaaatctt atccacctat aattgtatag ggatgacttg ggcgaatcga gaaaaataac
     1501 aaaacttgtt ttttcttaag caaaatttaa ggatggtcta gtattata
//
LOCUS       DAVMAH010000119         1504 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVMAH010000119 DAVMAH010000000
VERSION     DAVMAH010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.120"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            10..303
                     /locus_tag="VYO94_002069"
     CDS             10..303
                     /locus_tag="VYO94_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEV1760614.1"
                     /translation="MEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNKRLIEKGAV
                     FESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKDEIT"
     gene            617..1504
                     /locus_tag="VYO94_002070"
                     /pseudo
     CDS             617..1504
                     /locus_tag="VYO94_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836677.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
BASE COUNT          710 a          183 c          266 g          345 t
ORIGIN      
        1 agattaagta ttgaagaaca gattgaaaag aaagaagaaa gcattaagca attacaaaat
       61 caaaaaagac agttgaagaa aaaacttaat gaacaagaaa gaaaagcaag aaacaaaaga
      121 cttatagaaa aaggtgcagt gtttgaaagt atttttgaag aaagtattga tttaacaaaa
      181 gatgaatttt ataagttaat aaaaacgtta aatgatgaag aaataagatt aaacataatg
      241 gaaattttag aagaaagaat agatgataat gtagaaaaat catctaaaga tgaaataaca
      301 taattgtccc ttggttacaa gggcgcaatt atacacccta aagggtgctt gcgtcctgcg
      361 gagtcaaacc cttgcaggga gcaacaacca ttcgcttttt aaaagtcaag ggtaaataaa
      421 ctcgctaagg ctcgcccttg acttttaaaa tttgaaatga aagtaacgat taagccgaca
      481 tactgaaaca acaaaaatta attcagtagt cggctttttt aattctatca tttcaaaacg
      541 ctcattcaca aagaggatat aaaaaaacta ttaagcctcc acctaaaaca acaaagaaag
      601 aaaggaagtg ataaaaatgg cagacagttt tcatttttca gtaaacataa tatcaagagg
      661 aaaaggcaaa agtgcagtag caagtgcagc atatataagt ggagaaaaaa taaaaaatga
      721 atgggacgga gtaacccatg actacacaag aaaagaaaaa atattagtaa aaaatataat
      781 attgcctgat catataccaa aagaatttaa tgataggtct accttatgga ataaagtaga
      841 aatggcagaa aaaaattcta atgcacaact agcaagacaa ttcataatag gactaccaaa
      901 agagttatct ttaagtgaaa ataaaaacct ggttgaaaga tatataaaag aaaatttaac
      961 atcacaagga atgatagtag attatgcaat tcatgatgag agtcaagata aaaatggaaa
     1021 tatccattgt catataatga ccataatgcg accaataaac gaaaaaggag agttcttagc
     1081 caagtcaaaa aaaagaatat atcctagatg aaaaaggaga aaaagtatta aacaaaaatg
     1141 gaaaaccaaa gacaagaaaa gtagaactaa caacctggaa cgatacaggc aatgtagaaa
     1201 aatggagaga aaatttttca gatctttgta acaaatattt agaaagagca ggagcagaaa
     1261 aaagagtaga ccatagagtt ttaaaagaca aaattcagat tatctaccga caatccattt
     1321 aggatcagca gcaagtgcaa tggaaagaaa gggaatagaa actgacaagg gaaactataa
     1381 tagagaaata agaaaatata atcaacttgt aaaaacaata aaagaagaga taaaaacatt
     1441 aaagggttgg ataggaaatt tattagataa cttatctact gcttatgaaa aatttaagga
     1501 tata
//
LOCUS       DAVMAH010000120         1492 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVMAH010000120 DAVMAH010000000
VERSION     DAVMAH010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1492
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.121"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            134..1312
                     /locus_tag="VYO94_002071"
     CDS             134..1312
                     /locus_tag="VYO94_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1760615.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT          558 a          267 c          213 g          454 t
ORIGIN      
        1 tattttttat tatcaatata taataaaaag agaccagtaa gcaatgaaaa gcttaaaaag
       61 attaacatct acatttatcc atagcaaaaa atcataggat tttaagaatc tgacaactag
      121 gaagaaaact aatatgacct tatctaagaa acaattacaa ctaagagcta aaatactgga
      181 aacagtttac acattaggtc ccatttcacg aattgaaatc gctactaaaa caggaataac
      241 acctgcaaca actagcagta tcacaaatga tctgattaaa gaaaatattc tcttagaact
      301 tggtgaagac gaacacgata caagcgtagg gagaaaaaaa atcctgctag acattcaagc
      361 taaacgattt tactacattg gttgtgaact atctgaaaaa catttcactt ttgctttagg
      421 agataatcta ggaaatatct taaaggaaga gaaagaaatt gttactaaac agttaatcca
      481 agaaaaggga aatcaactca ttaaccagac actaaagcaa ttcttaaata actgctctga
      541 ttatgaaata gaagcaattg gaatcgcgct acctggtcgc tatttagata attataaaat
      601 aacaacaaac aatcctttat ggcaacatat cgacttagaa atgattcaat cccactttga
      661 taagcctttg tttttctcta acaatgttaa ctgtatggct ataggtaaac gcctatttag
      721 tcgccaacag aatgacccta attttgctta ttttcatttt gctagaggta tgcactgttc
      781 ttatatctac gacggaaaca tttatgggaa aggaaatcta atgattggag aaatagggca
      841 tacagttgtt tcatctgagg gagaagaatg tagctgcggg cgcaagggat gcttacaaac
      901 ttttgctgga gaatcttggt taatcaaaaa atcaaaaatt ctatatcatc aatctcccta
      961 ttctctactt cctagtttag tcaaaaatgc cgatgatatt gatatccaag ttattttaac
     1021 cgcttatcaa ttaggtgaca ctggaataat cacacttatc catcaagcct tactctatct
     1081 tagtcaaacc attttaaata tcagtatgat gattgactct caaaaaatct acctacatag
     1141 tcctttacta acaaatcaac acatcatcca aaaactatat agtgaaatga actacaaacc
     1201 caaactgctc tataatcgcc tacctgaagt cattattgaa ccttacaatg attttacagc
     1261 cgcacactca gctattgcac tttgtttgta tcatacaatt ctacattctt aattttctat
     1321 tacatttaat aaataggcta aaaagaggga gtatatcata aaaagcgaat aaacctgttt
     1381 tctgaaaatc agaattctgt tttgttcgct ttctttatat ttggaattat actcctatct
     1441 cccctttttc ataatgtata ataaaatgaa ataataacag gacgaatcgc tc
//
LOCUS       DAVMAH010000121         1221 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVMAH010000121 DAVMAH010000000
VERSION     DAVMAH010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1221
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.122"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(<1..405)
                     /locus_tag="VYO94_002072"
     CDS             complement(<1..405)
                     /locus_tag="VYO94_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760616.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLE"
     gene            complement(402..734)
                     /locus_tag="VYO94_002073"
     CDS             complement(402..734)
                     /locus_tag="VYO94_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1760617.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            complement(790..>1221)
                     /locus_tag="VYO94_002074"
     CDS             complement(790..>1221)
                     /locus_tag="VYO94_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760618.1"
                     /translation="NQNKWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQ
                     STFLTDSELFEDILKKIEDSHNTLLCTGLVELLLYEISISNNNNWSNKVDKIRIHLIR
                     INQLDFFYYTSWLRQNFDFCMNREYHKMKSRKLLLSNKKIV"
BASE COUNT          417 a          222 c          163 g          419 t
ORIGIN      
        1 ctctaaatat tttatccaag gagattgaga caccttgctt ctaaactgac taattttctt
       61 atattcgtta gtcaatttag tagcaaaatc ttccccaatt aaatgaaaga ttgctaactc
      121 taggataaaa acacttatta atacggtata agtcaaaaaa ctttctggga aaaacttatt
      181 gattaaaatg gggaaactca ttaacagaat cgaatttatg gctagacaga tagatactat
      241 tttatttttc acagaatata gaggtagtga tactattgag tagataaaag ctaaaaaaat
      301 aagcaaaaaa tactccgtgt catttataat cgccctgaat gataaaaata tatacatcca
      361 acatacgata atatgtattt ttcgaatctt atctacatta ttcatcttac tgtcgcagat
      421 ataaatccat cccaaggata agggttcccg ctaatatcac aacctctatt aagagcacca
      481 tatccaatac agtaagctat ttttcctgct gctgcaccaa taagccagcc tccaagacct
      541 ccaaccttaa tatagtttat tagttttttg gttaaaactg cagctccagc taatgctata
      601 aaagttcctg aactcatagc taaagctacg caaattcctt gacaagcacg cttgcttaaa
      661 taagctcccc catcaagata catcatttct tcttcatcaa tcacaacata attatttggt
      721 aatacaagtt ccatttgttt tctcctcctt agttgaaatt gtttcatttg ttttacaaat
      781 aggacgaact taaactatct ttttattact cagtaataat ttccgagatt tcattttatg
      841 atactctcta ttcatacaga aatcaaaatt ttgccttaac caacttgtat aatagaaaaa
      901 atctaattga ttgattctga tgaggtgtat cctaatttta tcaaccttgt tggaccagtt
      961 gttattgtta ctaatagaaa tctcatacag cagtaactcg acaagacctg tacacagaag
     1021 ggtgttatga gaatcttcga tttttttcaa aatatcctca aaaagttcac tatccgttaa
     1081 aaaggtggat tggttcatcg catcatagag aagaagggac attaagtcag aatagcttaa
     1141 ttctgatttt tgtattttgt ccatcaatat cttatgcaaa ttactttcaa atgaatcttc
     1201 tttttgccat ttgttttgat t
//
LOCUS       DAVMAH010000122         1184 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVMAH010000122 DAVMAH010000000
VERSION     DAVMAH010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1184
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.123"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(<1..274)
                     /locus_tag="VYO94_002075"
     CDS             complement(<1..274)
                     /locus_tag="VYO94_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1760619.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDIPKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEEIILYNFLSQME"
     gene            complement(287..693)
                     /gene="cdd"
                     /locus_tag="VYO94_002076"
                     /pseudo
     CDS             complement(287..693)
                     /gene="cdd"
                     /locus_tag="VYO94_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            complement(780..>1184)
                     /locus_tag="VYO94_002077"
     CDS             complement(780..>1184)
                     /locus_tag="VYO94_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diadenosine tetraphosphate hydrolase"
                     /protein_id="HEV1760620.1"
                     /translation="FVEMSYSQFFEGYCILFSKEPYPSLSDMPMEFRKEFLMEMSILG
                     DAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRKTVVHRYDSSVFSNPEFE
                     FTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
BASE COUNT          416 a          211 c          140 g          417 t
ORIGIN      
        1 attccatttg agacaagaaa ttatataaaa ttatttcttc tccatttaac agataatgga
       61 catcataata ttccttatga ctttcccacg gtctattttc ttcagttgta gtttccatat
      121 caattatatt gtaaaagaaa tcagtagaaa ttttatgtat gccaccttta tcttttggta
      181 tatcatgatt atttagaaac tcttttactt tcgttattgc gatatgctca tgaaccgtat
      241 taacatgtcc atttttaaat tcaactaatt ccatagttcc ctcctgttat aaattttctt
      301 gattaaaact aactggtagt agttctttaa gtttatatac tttataagta tcaacatcac
      361 tagccaatat aactacaaat gaatcaagat tacaaaattc tatcattacc tggcgacaca
      421 ctccgcaagg tgctataaaa gatgataaga taccattttt tccacctaca atacatattc
      481 ttgaaaacga acgttctcct ttaaatacag ctttataaaa agatactcgt tctgcacagc
      541 aagtaggaga aaaagcagca ttttctatat tacatccaga aaaaattttt tatcttcagt
      601 tactaacgca gctccaacct taaaatcaga ataaggagca taagctttgg ccattgattt
      661 aatagcctct gatataattg ctttataagt cattcctaaa atatattttt caaaaaatta
      721 tatcatccac aacctagttg taatatacaa ggtattaaat ctaatcgaaa atgtggagtt
      781 cagtttgaat catctaataa ttgttgatac tctctataat gtctatcaat agcagacctc
      841 agttttttaa taattggtcc atgcttttct atagtaaatt caaactcagg attgctaaaa
      901 actgaagaat catatctatg aactacagtt tttcttctct cttcctcttc ccacatgtat
      961 cgcggaaata aatgagcatg aagtacaggt gttgaatttc ctaagatatc ataattaatt
     1021 ctataggcat ttaacacttc aagcatcgca tcacctaata tactcatttc cattaaaaat
     1081 tcttttctaa attccattgg catatcagat aaagaaggat agggttcttt tgaaaaaaga
     1141 atacaatatc cttcaaaaaa ctgagaataa gacatttcta caaa
//
LOCUS       DAVMAH010000123         1014 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVMAH010000123 DAVMAH010000000
VERSION     DAVMAH010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.124"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            90..440
                     /locus_tag="VYO94_002078"
     CDS             90..440
                     /locus_tag="VYO94_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1760621.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSNIHVLLSMPYSVQDFYTNIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            763..996
                     /locus_tag="VYO94_002079"
     CDS             763..996
                     /locus_tag="VYO94_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760622.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT          316 a          202 c          221 g          275 t
ORIGIN      
        1 tgctaaaata tttctataaa ttaatttgac tttcctgata gagttattca catcttattt
       61 caactcacta tagaaggagg aataggagga ttctcagaca tccgggcatc agcccaacta
      121 atgatttgat tgctaagaaa atattcagca atccagaaat cacttgtcaa tttattcgcg
      181 atatgctgga tttgccagcc aaaaatgtga ccattttgga gggtagcaat attcacgtat
      241 tactctccat gccttactcg gtgcaggatt tttataccaa tatagacgtc ttggcggagt
      301 tggataacgg tactcaagta attattgaga ttcaagtcca tcatcagaat tttttcatca
      361 atcacttgtg ggcttacctg tgcagtcagg ttaatcaaaa tcttgaaaaa attcgtcagc
      421 gagaaggtga tactcactag agctacaaac acatcgctcc tgtttacgcc attgctatcg
      481 tggatagtaa ttatttctca gatgacctgg cttttcatag ctttagtatg cgcgaagaca
      541 caacaggtga ggtattggcg attaccaaca atggacagga aaaccatctg gttaagatgg
      601 cattcttgga attaaaaaat acagagaaac cagcaaagac aaggttcgca agccatggtt
      661 ggagtttttc gggaacaagc cctttaccca gcaaccgcaa cgagccatta cccaagcaaa
      721 tcaactgctg gactacaaga gctggtccga ggggacagga aaatgtttag tcaactacat
      781 atgcgagaag aacaagtctt gttagcacag gactatgcct tggaaaccgc tagggctgaa
      841 ggccttgaac aaggactaga gcgtgggaaa gttgaaggaa gggcagaaag gaaacttttt
      901 gccttcctag acatagtacg ccaaggtctt ctgacttctg aggttgccag ccagcaatta
      961 ggtatgtcag tatctgaatt tgaggcactg ttgtaaaatg gctccataat atcc
//
LOCUS       DAVMAH010000124          952 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVMAH010000124 DAVMAH010000000
VERSION     DAVMAH010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.125"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(<1..98)
                     /locus_tag="VYO94_002080"
     CDS             complement(<1..98)
                     /locus_tag="VYO94_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEV1760623.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSV"
     gene            complement(111..860)
                     /locus_tag="VYO94_002081"
     CDS             complement(111..860)
                     /locus_tag="VYO94_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV1760624.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYESQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          332 a          189 c          107 g          324 t
ORIGIN      
        1 acagaatcta tatcatatgc aacaacttta tatttagatg caaatagtaa cgcgtaggcc
       61 agcccaacat gccccaaacc aattactgct atattcataa aactacttcc ttatttctta
      121 atccaaaatc taatagaata agctgcccca ttccttaaat acaactcttt aatattgttt
      181 aaaagttttt caactgattt ccagattatc aaaatctgag attcatagca caatattgat
      241 gatattctat caatataatg tttttcatca agttcctctt gatacatttt taattcttta
      301 gtttttccca tataactaac catactacta tcacttacat atgggaagtc ctcataatat
      361 attactttat aacgcataaa ttcaagcgcc cttccaatac tattcacaaa aacatgatca
      421 acatggtcac caagtgaaag cggacaatat acgacacatt tgtcgtctaa atgcattaac
      481 agctctttta tgatatcatt ctttaatgtg tcctcatttt ttaattcact atagatatga
      541 cggtatagaa aattgccatt tctatctttc ctatagagac attcatagta cgataagtgt
      601 ctaaaatcac actgtagacg ttcacaagct aacctgtctt ctttcttcct ttcttcaatc
      661 ggatatttcc caaggttaca caacttatga aattgcttag cagagggctg tagctgttgg
      721 ctcaaagggt aaccagaaaa tatagtaata acaagtacaa tttctccttc tgaagttaat
      781 tttgaaatat aatcaccaca ggaaaaaatt gcgtcatcta aatgtggaga taaaaatata
      841 tacttagtat tgttactcat aaccattccc tctacaattt atctaaaaat tcactaagtg
      901 tctgattaaa ttccacatca tcaaaaaaat tcaccttatt cttaataatg aa
//
LOCUS       DAVMAH010000125          909 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVMAH010000125 DAVMAH010000000
VERSION     DAVMAH010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..909
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.126"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            18..807
                     /locus_tag="VYO94_002082"
                     /pseudo
     CDS             18..807
                     /locus_tag="VYO94_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          305 a          155 c          183 g          266 t
ORIGIN      
        1 aatcattcta tagtaaaatg aaacaagaac aggacaaatc gatcaggaca gtcaaatcga
       61 tttctaacaa tgttttagaa gtgggggtgt actattctag tttcaatcta ctatatttcg
      121 tctgatgggc aaatcttata aagagattat agagctttta gactgtaatc aaacaacgat
      181 ttagcgaaat gtaaaaaaat atgaggagtt cggactcgac tctctccttc aagaaacacg
      241 tagtggtcgt aaccatgcat atatgacagt tgaggaagag aaagcctttc ttgcccgtca
      301 tttgaaggct gcagagtcag gagaatttgt tacaattgat gccttatttc aggcttataa
      361 aaaggagtta ggtcgttcct acacacgtga tgccttctat caactgttga agcgccatgg
      421 ctggcgaaat attatgccac gtccagaaca tcctaagaaa gcagacgctc aaaccattgt
      481 cgcgtctaaa aataaaatct caattcaaga agacaagaaa gcgctttaaa atcagtagac
      541 gttttcgtaa ggttcgcttg atgtaccaag atgaggctgg tttcagtaga atcagtaaac
      601 tgggatcttg ttgggctcca ataggagtag gtccacatgt ccatagtcac tatatacgag
      661 aatttcgcta ttgttatgga gctgttgatg cccatattgg aagatgtcat aaatcaactt
      721 caagatgtca tacaaggact ggagaaagag gtgataaagt ccatcgttaa tcggagatgg
      781 actagaatgc tttttgaaaa cagatgagta ttaaatattt taaaattctt aatccctgaa
      841 agtactttca gttaaatttt taccttaaaa acaactttct taatattaat tggttcttca
      901 accaatagg
//
LOCUS       DAVMAH010000126          880 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVMAH010000126 DAVMAH010000000
VERSION     DAVMAH010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.127"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            1..711
                     /locus_tag="VYO94_002083"
                     /pseudo
     CDS             1..711
                     /locus_tag="VYO94_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(807..880)
                     /locus_tag="VYO94_002084"
     tRNA            complement(807..880)
                     /locus_tag="VYO94_002084"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(844..846),aa:Asn,seq:gtt)
BASE COUNT          289 a          204 c          133 g          254 t
ORIGIN      
        1 gctgaaactt ctatcgtcaa gaagaatcac caaatccctc gtattatcaa ccaaaagatt
       61 gctcaaaagt taattgaaaa gatttctatg accgacattg atcatcagtt gtctatttca
      121 acttcaactg tcattcgcaa gatcaatgat tttcactttg agcatgattt ttcgcgtctt
      181 cctgagatta tgtcctagga cgttgaaaca gtctggggag tgactgtttc aatcgggaaa
      241 tagagatgag ctttattgct caggactttg ataagctcaa tatcataact gttcttgaga
      301 gcagaacaca agccatcatc cgaaatccca tgaatacaag gctatcaagc gatactgaaa
      361 gctcattcaa caagatagtc agaaactgag tgataaacga ttttatcgcc ctacttttcg
      421 tatgcacttg actaataaag aaattctaaa taaacttttg agctattccg aagacttgaa
      481 acaccactat aatctctatc agctcttgct tttccacctc tttttcagac tttgtttaaa
      541 accttcctca aagataaaga gaaaatcgtc aacgcccttc aattacctta ttccaacgcc
      601 aaactggaag ccaccaataa tctcatcaaa cttatcaagc acaatgcctt tggttttagg
      661 aactttgaaa acttcaaaaa agaaaggacg aaatttgtcc tttctagatc ttcgctttct
      721 tcaacccact acatcttcgc tttcttcaac ccactacagt tgacaaagaa ccacaaaaaa
      781 gaggtctaaa cctcttaact caattactcc gccagtagga ctcgaaccta cgacatcatg
      841 attaacagtc atgcgctact accaactgag ctatggcgga
//
LOCUS       DAVMAH010000127          719 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVMAH010000127 DAVMAH010000000
VERSION     DAVMAH010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..719
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.128"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            57..266
                     /locus_tag="VYO94_002085"
                     /pseudo
     CDS             57..266
                     /locus_tag="VYO94_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943159.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            321..>719
                     /locus_tag="VYO94_002086"
     CDS             321..>719
                     /locus_tag="VYO94_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1760625.1"
                     /translation="MEGSLFECGVILQYYLGRLLFQKGNTSILCGESADEIMTFKYHS
                     VNYNQFCNDKQKSVYFSYSDYPFYVTNSIVLKKNSLLLHSFGIHPRYPYKMSEIVEMS
                     KKISDLNDKKEFHKKNCELRFQDSVLDNINS"
BASE COUNT          263 a           84 c          127 g          245 t
ORIGIN      
        1 attataatga ttcaaacaat tttactaaag aacaagtatt aaagaattgg gactctatgc
       61 tacgtgaatc tatattaaga gtgtatagtg aagcaggaga ggctaatatt acactatcat
      121 ctggttttga ttcaaattat atattatata cattagcgaa ttatacgaat tcttcaatta
      181 atgcattttg cataggagga gaaaaaggaa ttaatgagat tcctgaagta actaaaattg
      241 caaaatttta tggtataaat ttattagttg atactgtaat gagccaagat ttagaatatt
      301 ttcccgatat agtatggaga ttggaaggaa gtctctttga atgtggtgtc atactgcagt
      361 actatttagg caggttgttg ttccaaaaag ggaacacaag tattctttgt ggcgagtcag
      421 cggatgaaat aatgactttt aagtatcatt ctgtgaacta caatcaattt tgtaatgata
      481 aacagaagtc agtatatttt agttattccg actatccatt ttatgttaca aattcaattg
      541 ttttaaagaa aaatagccta cttttgcata gttttggcat tcatcctaga tatccatata
      601 aaatgtctga gattgttgaa atgtctaaaa aaatatcaga tctaaacgat aaaaaagaat
      661 ttcacaaaaa gaactgtgag ttgaggtttc aagatagtgt tcttgataac ataaatagt
//
LOCUS       DAVMAH010000128          699 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVMAH010000128 DAVMAH010000000
VERSION     DAVMAH010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..699
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.129"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            <1..>699
                     /gene="phtB"
                     /locus_tag="VYO94_002087"
     CDS             <1..>699
                     /gene="phtB"
                     /locus_tag="VYO94_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV1760626.1"
                     /translation="HQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVEDILAFLAP
                     IRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTH
                     SHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVP
                     LDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYY
                     VEHPNERPHSDNGF"
BASE COUNT          222 a          139 c          155 g          183 t
ORIGIN      
        1 ttcaccaaga tttacttgat aataaaggtc gacaagttga ttttgaggct ttggataacc
       61 tgttggaacg actcaaggat gtctcaagtg ataaagtcaa gttagtggaa gatattcttg
      121 ccttcttagc tccgattcgt catccagaac gtttaggaaa accaaatgcg caaattacct
      181 acactgatga tgagattcaa gtagccaagt tggcaggcaa gtacacaaca gaagacggtt
      241 atatctttga tcctcgtgat ataaccagtg atgaggggga tgcctatgta actccacata
      301 tgacccatag ccactggatt aaaaaagata gtttgtctga agctgagaga gcggcagccc
      361 aggcttatgc taaagagaaa ggtttgaccc ctccttcgac agaccatcag gattcaggaa
      421 atactgaggc aaaaggagca gaagctatct acaaccgcgt gaaagcagct aagaaggtgc
      481 cacttgatcg tatgccttac aatcttcaat atactgtaga agtcaaaaac ggtagtttaa
      541 tcatacctca ttatgaccat taccataaca tcaaatttga gtggtttgac gaaggccttt
      601 atgaggcacc taaggggtat actcttgagg atcttttggc gactgtcaag tactatgtcg
      661 aacatccaaa cgaacgtccg cattcagata atggttttg
//
LOCUS       DAVMAH010000129          651 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVMAH010000129 DAVMAH010000000
VERSION     DAVMAH010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.130"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            complement(252..632)
                     /locus_tag="VYO94_002088"
     CDS             complement(252..632)
                     /locus_tag="VYO94_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HEV1760627.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
BASE COUNT          231 a          149 c           73 g          198 t
ORIGIN      
        1 taatctacca acctcttgtt tttaaataca tttcaagtcc aaactattct ttatagaaaa
       61 aagtcctata aattcgagca atagttaaaa tacaaacaaa tataattccc aaaatagata
      121 acactatttt cacaaaattc atttcagaac ctattatata tacgtgaaaa aaaggggcta
      181 ttcctacaca tatatacaat aaataactta caaagtttat ttcaccaatt cctgcaaaaa
      241 aatgtttcat tttaagcaaa aatataacca tctaagctac cgtcagccca atcagcccca
      301 tatgcgattg ctccacctag tgaaaatcca gtaacagtta gtgcaacgtt tagtgcagta
      361 ttgactaaat ggccagctgc actacctaca tgtttaatta ttaaactacg taatgttctc
      421 gtaatagccc ctctattagc tgagatagct ttttttatcg cataagcaga ataaattgtt
      481 gcaccaccac tatagatggc caaacctaca tccagaactg ttgcaaaact acctctacta
      541 ttccaccagt tacgaccaac accaccccca tcaagataca tcatctcttc ttgctcaaga
      601 gcaacataat tatttggtaa tacgagttcc atttgttttc tcctccttag t
//
LOCUS       DAVMAH010000130          616 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVMAH010000130 DAVMAH010000000
VERSION     DAVMAH010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..616
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.denovo.131"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            15..616
                     /locus_tag="VYO94_002089"
                     /pseudo
     CDS             15..616
                     /locus_tag="VYO94_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          214 a          113 c          132 g          157 t
ORIGIN      
        1 ccacttttga agagatgtta gctgtattaa aaacagctta tcaacttaaa cacgcaaaag
       61 gtggacgaaa acctaaatta agcctagaag accttcttat ggccactctt caatatgtgt
      121 gagaagaccg cacttatgaa gaaattgcgg ctgatcttgg tattcacgaa agcaacttaa
      181 tccgtcggag ccaatgggtt gaagtaactc ttgttcaaag tggtgttacg atttcaaaaa
      241 ctcatcttag tgctgaggat acggtgattg tggatgcaac agaggtaaaa ataaatcgtc
      301 ctaaaaaaat caactagcca attattctgg taaaaagaaa tttcacgcta tgaaggctca
      361 agcgattgtc acaagtcaag ggagaattgt ttctttggat atcactgtga actattgcca
      421 cgatatgaag ttgttcaaaa tgagtcgcag aaatatcgga caagctggaa aaatcttggc
      481 tgacagtggt tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc
      541 cagcaaactc aagccgctaa cagttgaaga taaagcctgt aatcatgcgc tatctaagga
      601 gagaagcaag gttgag
//
LOCUS       DAVMAH010000131         5658 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00069809
            SAMN33607393-rid17955553.guided.076, whole genome shotgun sequence.
ACCESSION   DAVMAH010000131 DAVMAH010000000
VERSION     DAVMAH010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607393
            Sequence Read Archive: SRR23725467
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721344.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721344.1
            Genome Coverage       :: 391x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 00:30:39
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,095
            CDSs (total)                      :: 2,047
            Genes (coding)                    :: 1,915
            CDSs (with protein)               :: 1,915
            Genes (RNA)                       :: 48
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 42
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 68 of 132
            Pseudo Genes (incomplete)         :: 53 of 132
            Pseudo Genes (internal stop)      :: 49 of 132
            Pseudo Genes (multiple problems)  :: 32 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607393-rid17955553.guided.076"
                     /strain="AUSMDU00069809"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
     gene            307..735
                     /locus_tag="VYO94_002090"
     CDS             307..735
                     /locus_tag="VYO94_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1760628.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            804..1391
                     /locus_tag="VYO94_002091"
     CDS             804..1391
                     /locus_tag="VYO94_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEV1760629.1"
                     /translation="MGGNPPIKNYTIVNKIVSSRKIERIVIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            1631..1909
                     /locus_tag="VYO94_002092"
     CDS             1631..1909
                     /locus_tag="VYO94_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HEV1760630.1"
                     /translation="MEKVASLGVPMCKPISIELCDDEVHSLHEWIDGRDAIDSILTYS
                     ENQQYTYGVEAGKILRKIHTIPATEVCEDWEIFFNLKIDDKISNEMIW"
     gene            2014..2343
                     /locus_tag="VYO94_002093"
                     /pseudo
     CDS             2014..2343
                     /locus_tag="VYO94_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            2471..3700
                     /locus_tag="VYO94_002094"
     CDS             2471..3700
                     /locus_tag="VYO94_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1760631.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            3720..>5658
                     /locus_tag="VYO94_002095"
     CDS             3720..>5658
                     /locus_tag="VYO94_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV1760632.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNL"
BASE COUNT         1846 a          907 c         1180 g         1725 t
ORIGIN      
        1 atacacacaa ggaaatcatc gccaaactgg actacgacgc accatgttga ggcagtatca
       61 ctgcttgtac aagctgaggc atcagcgaag tagaagtaaa tgatctccca tacgatagga
      121 ctcgtagaat gaggagggaa accgacgaaa tgataaggta agtccgaacc gctgagtgcg
      181 tggctctgct cttccgatct gagacagtcg aaaagtagaa ggggatggta ttggtatcaa
      241 tcaatgagta acaaagtatc agcatgattc gaaacattta cttgtaattt gcggaggaac
      301 atcaatatgg atggaataac aaaagatttt ataaaaacgg ctaaactaat gaaacaatta
      361 tggccccaat tgaccgataa agaagctatt gatgaagtaa aaaaatatac gaatggcaaa
      421 aatactgcaa tctttactga agttgaaggt gacacaattg taggtctagc actatgttca
      481 ctcagatttg attatgttga aggttgtaaa tatagtcctg ttggattctt agaagggatt
      541 attgttgacg aggaatatcg tttaaaggat attgctaaaa atctctgtac aaaatgtgag
      601 gaatgggcga aaaataaagg atgtaaggaa tttgcaagtg actgtacttt aacgaatacg
      661 gattctataa gatttcatct caatattgga tttcaggagg caaatagaat tattcatttt
      721 aagaagaaat tataatttca gaacgtggtc aaaatttatg tatctttaga aagcgtgaaa
      781 gattggacga acaaattttt ttgatgggtg gaaatccgcc gataaagaac tatacaattg
      841 ttaataaaat tgtgtcatca aggaagatcg aaagaattgt catttttaca gtttttcgag
      901 aaaattggga accgtacatg aaaaagtaca cggaagtttt tcaaagtcaa tttcctaatc
      961 taaacattga ttacttgctc ctggacactg agcagattga tcttgatagc tatctagatg
     1021 ctgacataat tatcatcggt ggtggaaata cggaaaaata tattgctact tatgttaatc
     1081 aggagttcaa aagttatatc gatcatatgc ttaataaaga ggcaaaaatt ataggatttt
     1141 ctgcaggagc cctactatta ggagaaaaag tctatgtctc acctaatgat aattcagatc
     1201 atcagataaa gataaaaaat ggattaggac tctttagtca gtttttaatt agtgtccatt
     1261 atgattcctg gaatgataaa gcaaataagg atagagctga agaactcgtt aatgttccca
     1321 taattccact aaatgatcat tcttgtcttg tattggataa acttggaaac atcatagaga
     1381 aaattgacta actttcataa tgtaaaaatg gatctaggaa ataaaagtgt agacgaactg
     1441 gataggttac tagtgaaaac tgcaaaaagt gttgtaaagt gaatcggagt gttttagtag
     1501 taagatagcc ataaataaag gctggtcaga tgataaaaaa tattgtgtga cagttcaaaa
     1561 tcagtaaaca tatttcttgc gtgtttctga taagtcgaag ttagattata aaaaaattga
     1621 atttgatacg atggagaaag tagcttctct tggagttccg atgtgtaaac caattagcat
     1681 tgaactctgc gatgacgaag tacattcttt acacgaatgg atagacggaa gagatgcaat
     1741 agatagcatt ttaacttatt cagaaaacca acaatacaca tatggtgtag aagcaggaaa
     1801 gatacttaga aagattcata caattcctgc tacagaagtt tgtgaagatt gggaaatctt
     1861 ttttaatcta aaaattgatg ataaaatctc caacgaaatg atatggtaag tccgaaacgc
     1921 tcagtgtgta agcttgttgc taaaagcgta aaaaccttgg aacgaaagga ataatagact
     1981 tcctgcgaaa caaaaataca atacaataaa actatggatg atgaagcaag taaacaattg
     2041 agcgatagcc gtttcaagat ccttgtaggt gttcagcgca cgacttttga agagatgtta
     2101 gctgtgttaa aaacagctta tcaacgtaaa cgcgcaaaag gtggacgaaa aaccaaatta
     2161 agcctagacg atctccttat ggtaactatt caatacatgc gagaatagcg cacttatgaa
     2221 caaatttcgg ctgattttgg cattcacgaa agcaacttaa tccgtcggag tcaatgggtt
     2281 gaagtaactc ttgttcaaaa tggttttacg atttcaaatt ctgctctaat tatgaaaaac
     2341 agtaaaattc gaaggattat aaggtaagag tttttttctt tctgaaaaaa tggtataata
     2401 gcaatcaaaa ctagaaaata aaacggaatt tggaacagat ttgtctgtat cctagtagag
     2461 tggtgatgct atgaagatta gtaagaggca cttattaaat tattccatct tgattcccta
     2521 cttgctttta tctattttgg gcttgattgt ggtctattcg accaccagtg ctattttaat
     2581 tgaagaaggc aagagtgcct tgcagttggt tcgaaaccaa ggaatctttt ggattgttag
     2641 tttgatactg attgccttaa tttataaatt gagactagat tttttgagaa atgagcgact
     2701 aatcatttta gttatattaa tagaaatgct tttattgttc ttggctcgtt ttattggtat
     2761 ttcagtaaac ggggcatacg gttggatttc ggttgcagga gtaactattc agccagctga
     2821 gtacttaaaa atcattatta tttggtattt agctcaccga ttctccaaac agcaagaaga
     2881 aatagctact tatgattttc aagttttgac tcaaaatcaa tggcttcccc gtgcttttaa
     2941 tgattggcga ttcgttctcc tagttctgat tggaagtttg ggaattttcc ctgatttagg
     3001 aaatgcgact attttagtct tggtttcctt gattatgtat acagttagtg gaatcgctta
     3061 tcgctggttt tcaaccattc tggcgctcgt atctgccgct tctgtctttg tcttgaccac
     3121 tatcagccta atcggtgttg agaccttttc aaaaattcca gtattcggct atgtagccaa
     3181 gcgctttagt gcctttttta atccttttgc cgatcgtgct gatgcaggtc accagttagc
     3241 taattcttat tttgccatgg tcaatggcgg ttggtttggt ctaggtcttg gaaactcgat
     3301 tgaaaaacga ggttatttgc cagaagctca tacagacttt gtcttttcta tcgtgattga
     3361 agaatttggc tttgttggtg ccagtcttat tttagctctc ttgtttttca tgattttgcg
     3421 gattatcttg gtcggtatcc gagcggagaa tcctttcaat gccatggttg cactcggtgt
     3481 cggagggatg atgttggttc aggtatttgt caatatcgga gggatttcgg gcttgattcc
     3541 atctacagga gtgactttcc ccttcttatc ccagggtgga aatagtcttc tagtcttatc
     3601 agtggcagta gcctttgtct taaatattga tgccagtgaa aaacgcgcta aattgtaccg
     3661 agaattggaa aatcaaccaa tgaaccttct gttgaagtag gataaagaaa ggatagttta
     3721 tgtctcttca aaaattagaa aattatagta ataaaagtgt tgtgcaagaa gaagtcttga
     3781 ttctaacaga attactggaa gatattacta aaaatatgct tgccccagag acctttgaaa
     3841 aaataataca gttgaaagaa ttatcaacgc aggaagatta tcaaggtcta aaccgtctag
     3901 tgactagctt atcaaatgat gaaatggtct atatttcacg ctatttctct atcttgcctc
     3961 ttttgattaa tatttcagag gatgtggatt tagcttatga aatcaatcat caaaataata
     4021 ttgatcagga ctatttaggt aaattatcta caacgattaa attggtagca gaaaaggaaa
     4081 atgccgttga gatcctagaa cacttgaatg ttgtccctgt tttgacagcc catccaacac
     4141 aagtgcaacg caaaagtatg ttggatttaa caaatcatat tcatagtctt ttgcgtaaat
     4201 accgtgatgt taagttgggg ttgatcaata aagataaatg gtacaatgat ttgcgtcgtt
     4261 acatcgaaat tatcatgcag acagacatga ttcgtgagaa aaaattaaaa gtgactaacg
     4321 aaatcacgaa tgctatggaa tattataaca gctccttttt gaaagctgta cctcatttga
     4381 cgacggagta taagcgctta gcgcaagcgc atggtctgaa tttaaaacag gctaaaccaa
     4441 tcaccatggg tatgtggata ggtggtgatc gtgatggaaa tccatttgtt acagcaaaga
     4501 ccttgaagca gtctgcactc actcagtgtg aagtcatcat gaactactat gataaaaaga
     4561 tttaccaact ttatcgtgaa ttttctcttt caactagcat tgtcaacgtc agcaagcaag
     4621 tcagagaaat ggctcgtcaa tccaaggata actcgattta ccgcgaaaaa gagctttacc
     4681 gtcgtgcctt gtttgatatt caatcaaaaa ttcaggcaac taaaacctat ctgattgagg
     4741 atgaagaagt tgggactcgt tatgaaaccg ccaatgattt ctacaaggat ttgattgcca
     4801 ttcgagattc tctactagaa aataagggcg agtccttgat ttcaggtgat tttgtggaat
     4861 tattgcaggc agtagagata tttggttttt acttagcatc aattgatatg cgacaagact
     4921 ctagcgtcta tgaagcctgt gtggcagaac tcttgaaatc agcaggaatt cattctcgtt
     4981 atagcgagtt gagcgaagaa gaaaagtgtg accttctctt gaaagaatta gaagaagatc
     5041 cccgaattct ttctgcgact cacgcagaaa aatcagaatt attagcaaaa gaattagcta
     5101 tttttaagac ggctcgtgtt ttgaaagata agttgggaga tgatgtcatc cgtcagacca
     5161 tcatttcaca tgcaaccagc ctttctgata tgctagaatt agctattctg ttaaaagaag
     5221 taggactggt ggatacggaa agggcgcgtg ttcagattgt tccccttttt gaaacaattg
     5281 aagacttgga tcattcagag gaaacaatga gaaaatatct ttctcttagc cttgccaaaa
     5341 aatggattga ctcacgaaat aactaccaag aaatcatgct tggctactct gacagtaata
     5401 aagatggcgg ttacttgtca tcatgttgga ccctctacaa ggctcaacaa caattgactg
     5461 ctattggaga tgaatttggc gttaaggtta ccttcttcca tggtcgtggt ggtactgtcg
     5521 gtcgtggtgg tgggccaacc tatgaagcca ttacatctca accgctcaag tctatcaagg
     5581 atcgtatccg cttgacggag cagggtgaag taattgggaa taaatacggt aacaaagacg
     5641 ccgcttacta taaccttg
//
